RESTRICTED JND O. M-AB MEDICAL TAROTS REFERENCES FROM FOR THE TECHNICAL AND SURVEY OF JAPANESE ACTIVITIES SCIENCES p.S. NAVAL TECHNICAL MISSION TO JAPAN- U. S. NAVAL TECHNICAL MISSION TO JAPAN NS/ews CARE OF FLEET POST OFFICE SAN FRANCISCO, CALIFORNIA 5 December 194-5 RESTRICTED From; Chief, Naval Technical Mission to Japan. To : Chief of Naval Operations. Subjects' Target Report - References from the Committee for the Technical and Scientific Survey of Japanese Activities in Medical Sciences. References (a)"lntelligence Targets Japan" (DNI) of 4- Sept. 194-5. 1. Subject report, enclosing references from the Committee for the Technical and Scientific Investigation of Japanese Activities in Medical Sciences, in addition to targets outlined in Fascicle M-l of reference (a), is submitted herewith. 2. The report was prepared by Commander P.B. Ayres, (MC) USNR, C. G. GRIMES Captain, USN RESTRICTED M-AB REFERENCES FROM THE COMMITTEE FOR THE TECHNICAL AND SCIENTIFIC SURVEY OF JAPANESE ACTIVITIES IN MEDICAL SCIENCES "INTELLIGENCE TARGETS JAPAN”(DNI) OF 4 SEPT. 1945 FASCICLE Ml, ADDENDUM M-AB DECEMBER 1945 U.S. NAVAL TECHNICAL MISSION TO JAPAN RESTRICTED M-AB INTRODUCTION MEDICAL TARGETS REFERENCES FROM THE COMMITTEE FOR THE TECHNICAL AND SCIENTIFIC SURVEY OF JAPANESE ACTIVITIES IN MEDICAL SCIENCES The five enclosures submitted are rich reference sources, supple- menting the designated target reports of the Medical Section of the Technical Department, NavTechJap. Japanese medical research, practice, procedures, opinions of medical and scientific authorities in JAPAN, and materiel gathered in the field are all noted. It is felt that these references form a compact body of material which will be of value in indicating the amount and degree of Japanese medical research and the present levels of medical education in JAPAN. NTJ*L»M-AB M-AB RESTRICTED TABLE OF CONTENTS Introduction Page 1 List of Enclosures Page 3 Enclosure (A) Page 3 Enclosure (5) , Page 97 Enclosure (C) Page 147 Enclosure (D) Page 173 Enclosure (E) Page 253 2 RESTRICTED M-AB LIST OF ENCLOSURES (A) Final Report of the Committee for the Technical and Scientific Investiga- tion of Japanese Activities in Medical Sciences. (B) Research Projects and Findings of the Army Medical College, TOKYO. (C) Organization of Japanese Army Medical Department. (D) Translation of titles of articles in various Japanese Medical Journals which have been submitted to WDC for forwarding to the Army Medical li- brary. (E) Materiel and Equipment collected by Field Unit #4, 5250 Technical Intel- ligence Company, Medical Section. 3 RESTRICTED M-AB ENCLOSURE (A) RESTRICTED M-AB ENCLOSURE (A) FINAL REPORT OF THE COMMITTEE FOR THE TECHNICAL AND SCIENTIFIC INVESTIGATION OF JAPANESE ACTIVITIES IN MEDICAL SCIENCES TABLE OF CONTENTS Letter of 5 December 1945 from Committee Chairman to the Chief Surgeon, GHQ., AFPAC. Appendix "A" - Reports Listed Under Institutions . Page 8 I Tokyo Imperial University . Page 8 II Tokyo Imperial University Medical College Page 15 111 Tokyo Army Medical College Page 18 IV Keio University Medical College Page 23 V Okuba Army Experimental Station Page 25 VI Kitasato Institute for Infectious Disease, Tokyo ... Page 26 VII Institute of Physical and Chemical Research Page 26 VIII Tokyo Municipal Hygienic Laboratory Pago 2? IX Tokyo Naval Medical College ..... Page 2? X Technical Intelligence Page 30 XI Tokyo Institute of Public Health Page 31 XII Nagao Institute, Tokyo Page 32 XIII Chiba Government Medical College Page 32 XIV Niigata Government Medical College Page 33 XV Tohoku Imperial University Medical College, Sendai , Page 36 XVI Hokkaido Imperial University Medical College, Sapporo Page 41 XVII Hokkaido Imperial University, Sapporo Page 46 XVIII Ministry of Health and Social Affairs, Tokyo Page 48 XTX National Research Council of Japan Page 49 XX Kanazawa Government Medical College Page 54 XXI Kyoto Imperial University Medical College Page 56 XXII Kyushu Imperial University Page 60 XXIII Nagoya Imperial University Page 65 XXIV Okayama University Page 72 XXV Osaka Imperial University Page 76 XXVI Tokyo Jikeikal Medical University Page 79 XXVII Agricultural Experimental Station Page 80 XXVIII Yoga Medical Supply Depot, Tokyo Page 80 tyty Research Institute of Tuberculosis Page 81 XXX Wartime Research Commission Page 82 TXTT Educational Requirements for Medical Degree, Igakushl Page 83 Appendix WB" - Alphabetical List of Persons Whose Activities Have Been Examined Page 84 Appendix "C" - Items of Interest Uncovered During the Investiga- tion of Japanese Medical Activities Page 91 Appendix "D" - Alphabetical List of Institutions Screened (All Roman Numerals Refer to Appendix "A") Page 95 5 M-AB RESTRICTED ENCLOSURE (A) FINAL REPORT OF THE COMMITTEE FOR THE TECHNICAL AND SCIENTIFIC INVESTIGATION OF JAPANESE ACTIVITIES IN MEDICAL SCIENCES GENERAL HEADQUARTERS UNITED STATES ARMY FORCES, PACIFIC OFFICE OF THE CHIEF SURGEON (Advance Echelon) 5 December 45 TO: The Chief Surgeon, GHQ, AFPAO, APO 500, Manila THRU: The Chief Surgeon, Adv. Ech., Tokyo INFO: The Surgeon General, Washington, D.C, SUBJECT: Final report of the Committee for the Technical and Scientific Investigation of Japanese Activities in Medical Sciences. 1, This committee was established at Manila by Order No. 640 of the Chief Surgeon’s Office, GHQ, AFPAC, APO 500, dated 22 August 45, with the ex- pectation of benefiting from independent Japanese research and development in the field of medicine and thus gaining in the overall knowledge in this sci- ence. The delegated functions of the committee were; a. Examine and evaluate such Japanese installations and personalities associated with the medical sciences as may be practical during the occupation. b. Correlate the activities of the medical section of the Enemy Equip- ment Intelligence Units Attached to the armies. o. Engage in the investigation of such other phases of Japanese Medical activities as may be directed by the Chief Surgeon. 2. The Committee arrived in Japan in two sections. One came with an Eighth Army unit (4 2nd General Hospital) to Yokohama, arriving at the same time as the advanced echelon of GHQ, and the other approximately a month lat- er, with the Sixth Army (135 th Medical Group) to Wakayama, then to Tokyo. The committee operated as a section of the Chief Surgeonfs Office, Adv. Eoh,, Tokyo. 3. The plan for carrying out the investigation, as set up at Manila, was changed through force of circumstances and through prescribed procedure developing from the peaceful occupation and general cooperation from Japanese officials. The method of investigation that developed was, in general, as follows: Activities of the committee followed command channels, keeping in touch with the surgeons of the various echelons. Full cooperation was receiv- ed from each. Official liaison channels were utilized in dealing with the Japanese. In many oases the Japanese Central Liaison Office, on request through 0-2 Japanese Liaison, made available a representative to facilitated arrangements. 6 RESTRICTED M-AB ENCLOSURE (A), continued / 4. In the above manner, over the past 3 months, every city of import- ance in medical education and every first class medical institution associated with research and developments in Japan, was visited. The heads of the insti- tutions and professors of their departments were interrogated. Reprints and manuscripts were secured to supplement information gained during the interro- gation. It is believed that a complete screening of Japanese Medicine for new developments and methods was accomplished. 5. A vast amount of literature and information concerning all sorts of medical activity over the past 20 years became subject to examination. This forced the committee to become a "screening" rather than an "investigation" agency. During the screening procedure, new developments, original research since 1940, unfamiliar procedures and theories evolved, and literature produc- ed since 1940, were sought. 6, Through necessity, imposed by the scope of the mission, the commit- tee accepted statements and reports from persons interrogated which it was un- able to examine and properly evaluate. Many claims, some of them of definite scientific interest, were made by the Japanese, These claims, though not ac- cepted as factual have been reported in the periodic reports. They were con- sidered of interest and reported with that in view. 7* During the investigation other agencies, with somewhat similar in- terests, began their activities. These activities were coordinated with those of the committee as far as was possible. Information secured by the committee was made available to other agencies, when it seemed to be of primary interest of the other agency and to be reported upon by that agency. Thus, matters pertaining to Aviation Medicine were turned over to ATIG, FEAT; those pertain- ing to BW, to the BW officer, AFPAC; those of naval interest, to NavTechJap, SOAP, including research projects report from the Naval Medical College; those concerning the Atomic Bomb to the Atomic Bomb Survey; Technical Intelligence to G-2, AFPAC; and the Chairman acted as medical member of the Scientific In- telligence Survey, 8. Staff supervision of Medical Technical Intelligence was exercised through G-2, AFPAC, Plans, for the completion of technical intelligence cov- erage of Japan, were implemented. 9, The screening of Japanese Medical Activities in the Home Islands, with the exception of certain "Class B" institutions, which are considered of little consequence, it now completed, and such has been reported upon. 10., Attached, as Appendix "A", is a complete list of reports on institu- tions and special subjects. Attached, as Appendix “B", is a list of individu- als whose activities have been examined. As Appendix ”0”, is a list of items of interest, with reference to sections of the report, and Appendix "D" is a list of institutions screened. 11. Composition of the Committee was as follows: Lt. Col. William S. Moore, M.C. Lt. Col. James A. French, M.C. Lt. Col, Dan Tucker, M.C. Maj. Ray E, Trussell, M.C. Maj. Theodore G. Anderson, SnC. Maj. Arthur Stull, SnC. Maj. Charles L. Looker, M.A.C. Capt. John E. Toble, SnC. Capt. Edgar J. LaLonde, M.A.C. W. S. MOORE Lt. Col., Medical Corps Chairman 7 M-AB RESTRICTED ENCLOSURE (A), continued Appendix "An - Reports listed under Institutions. Appendix "B" - Persons whose activities have been examined, listed alphabeti- cally and by geographical areas. Appendix "C" - List of Items of Interest. Appendix MD" - Alphabetical list of Institutions screened. Distribution: Chief Surgeon, GHQ AFPAC, Manila 3 copies Surgeon General, Washington, D.C 5 info copies AC of S, G-2, GHQ,, AFPAC 7 " " Economic & Scientific Section, SCAP...I ” " Public Health & Welfare, SCAT 3 " " NavTeehJap - Comdr. Ayres 2 " " ATIG, FEAF - Capt. Castor 1 ” ” U. 5.5.8.5., Medical Section 1 " " APPENDIX "A" Reports Listed under Institutions I. TOKYO IMPERIAL UNIVERSITY Government Institute for Infectious Disease Manufacturing Department Parasitology Department Colloidal Preparations of Various Metals and Biologicals I. Vaccine - Japanese B. Encephalitis (Kitsoka) 11. Epidemiology of Japanese B, Encephalitis. 111. Dengue Acute Liver Necrosis Due to Infection of Shell- fish (Oysters and Mussels) The Action of Immune Serum on the Japanese En- cephalitis Virus Cultured in Vitro Infectious Hepatitis Virus Isolation and Culti- vation Dysentery of Unknown Etiology Occurring on Shikoku 8 RESTRICTED M-AB ENCLOSURE (A), continued TOKYO IMPERIAL UNIVERSITY Government Institute for Infectious Disease Manufacturing Department Director: Dr. Saburo Kojima Assistant: Dr. Hidetake Yaoi This department is responsible for the production of serum, vaccines, toxoids, and other biologic products. Results attained in the Research Dep- artment are immediately applied in this department. The laboratories have not been modernized. Samples of the products of this institute as well as cultures of strains of bacteria used and description of methods used will be forwarded under sep- arate cover. Attached is a list and description of blologicals prepared. TOKYO IMPERIAL UNIVERSITY Government Institute for Infectious Disease Parasitology Department Dr. Nobutaro Ishii The laboratory facilities are fairly good in this institute. Dr. Ishii does strictly research work and is probably doing the most important work in Tokyo on medical parasitology. The following subjects were studied: Kala-azar: Transmission studies. Has transmitted leishmania forms to barnsters by the oral and cutaneous routes. Reprints attached. Paragonimiasis: Dr. Ishii states that Dr. Yokogawa in Formosa has ob- tained good results in the treatment by means of emetine plus sulfanilamide. Drugs: 4, 4* - Diguaanidine-didhenylsulflde has proven very effective in the treatment of Kala-azar. Sulfadibrom-benzene found effective in the treat- ment of bird malaria (reprint attached). Sulfapyridine in experimental spir- ochmetesis recurrentis (reprints attached). * Animal helminthology: Reprints attached. TOKYO IMPERIAL UNIVERSITY Government Institute for Infectious Disease Colloidal Preparations of Various Metals and Blologicals Summary of Work of Drs. Yoneji Miyagawa and Y. Moriya I, Dealing with preparation of antimony powder colloid, silver powder colloid and other metal powder colloids. Antimony, silver or other metals (Cu, Au, Mg, Zn, Cd, Hg, In, Si, Sn, Pb, As, Bi, S, Se, Te, Mn) are evaporated in vacuum by an electric heating unit and dispersed on the surface of crystalline dextrose. Photographs of the dia- grams of the apparatus are attached. 9 M-AB RESTRICTED ENCLOSURE (A), continued The dry powder is stable in vacuum, heat resistant for five hours at BQOq and one hour at 100° C, It readily forms collodial solutions in water having the same solubility as that of dextrose alone (40$ or more). The aqueous preparations of the antimony colloid change color slowly due to oxidation of the antimony. These various colloidal preparations have been used intravenously in both humans and experimental animals in the treatment of certain protozoan, metazo- an and rickettsial infections as described below. 11. Dealing with the treatment of trypanosomiasis, leishmaniasis, schis- tosomiasis, clomorchiasis, filariasis, rickettsial disease and "lymphogranulo- matoisls ingrlmalis” with antimony or silver powder colloid. (1) Trypanosomiasis. It is reported that intravenous administration of 1,0 cc of 0,007-0.009 antimony powder colloid solution to mice infected (pre- sumably with Trypanosoma gambiense) at a time when the mice’were definitely ill resulted in rapid degeneration of the flagellates and their complete dis- appearance from the blood after two hours. Clinical recovery was complete in one day. Comparable results were claimed in the treatment of horses suffering from surra (T, Evansi) or dourine (T. equiperdun), with doses of from 50 to 200 cc of a one percent colloidal preparation. Excellent mlorophotographs show the reported degenerative changes in the trypanosomes. (2) Leishmaniasis. Data is submitted on the treatment of leishmaniasis in dogs and squirrels. Good results are claimed. The protocols suggest that there were fewer leishmania demonstrable in smears from the organs of the treated animals, that their spleens were smaller and the body weight greater. One human case of kala-azar, eight months duration, was reported cured in 66 days by intravenous injections of the antimony colloid. Apparently the powder used was three percent and was given in doses of 1,0, 1.5, 2.5 - grams in 50 cc of water. There were no toxic manifestations. A total of 10 doses were given in 24 days. A progressive improvement in the blood picture is tab- ulated. (3) Fliffrlasis. Treatment of eight cases of human filariasis using var- ious doses of one percent or three percent antimony colloid powder resulted in disappearance of the microfilaria. The higher doses employed sometimes caused anorexia, nausea, vomiting or coughing. The antimony preparation given to dogs infected with Dirofilaria immitis is reported to have killed not only the microfilaria but also the parent worm leading to embolic occlusion of the pulmonary artery. (4) Schistosomiasis. Five human oases of Schistosomiasis japonica suf- fering from diarrhea and malnutrition but without splenic or hepatic enlarge- ment were treated with the antimony preparation. The three percent powder was used in doses of 0.5. 1.0, 1.5, and 3.0 grams dissolved in 50 cc of water and injected intravenously every other day. Theeffs in the feces disappeared after the fourth and eighth injection and did not reappear within a month and one half. Nausea, vomiting and coughing were occasionally observed. The pa- tients gained weight and overcame their anemia. Seventeen similar patients treated with tartar emetic did not show such a favorable response although they were somewhat improved. Treatment of experimentally infected dogs followed by post-mortem exam- inations showed that adult worms and eggs had either completely disappeared or were degenerate. 10 RESTRICTED M-AB ENCLOSURE (A), continued Four severely infected cattle were treated; three recovered completely and one died during the course of therapy. At autopsy adult worms could not be found and eggs in the tissues were degenerate. (5) Clonorchlasls. Both dog and human cases are reported to have been cured. (6) Typhus. During a small typhus outbreak (type not stated) in Tokyo in 1943, seventeen patients were treated with a silver colloidal preparation. One (5.95) patient died. Among ill not treated 30 (29%) died. It was claimed that treated patients showed rapid clinical improvement. Antimony colloidal preparations were less satisfactory, since 10 (34.5%) among 29 patients so treated, failed to survive. (7) Lymphogranulomatosis Ingrlmalls, One case was treated with the antimony preparation with good results. 111, Dealing with the preparation of dry plasma, dry sera and bacterial toxins. This deals with drying plasma, serum and tuberculin by vacuum at 37" Centigrade, Dextrose is added for reasons which are not self-evident. The following had been successfully maintained at room temperature for at least one year: a. Suspensions of B. coli (mixed with silicates) b. Lymphogranuloma venereum c. Cod liver oil d. Red blood cells e. Colloidal suspensions of antimony f. Colloidal suspensions of silver g. Tubercle bacilli h. Tuberculin (for skin testing) i. Human sera (immune and normal) Hyperimune serum (diphtherium; antitoxin titres checked before and after) k. Plasma l. Quinine m. Plasmochine n. Ricketesia IV. Describing preparation of fat powder colloid and its use. By inter- mittently spraying fine droplets of oil on warm dextrose crystal kept under a low vacuum, powdered preparations of cod liver oil, butter, neutral fat, etc., were prepared. They contained from one to three percent of fat and could be added to water as 10 to 20$ mixtures. No fat globules were visible under the microscope. If the aqueous preparations were left at room temperature in the open air some visible separation of fat occurred after 10 hours. The 10 to 20$ mixtures were used for intravenous injections in humans in doses of 50 to 150 cc every fourth day. An interesting series of weight curves were accumulated showing considerable Improvement in malnourished pat- ients. V. Describing preparation of a "powder colloid of whole blood" and its use. Small amounts of whole blood are added repeatedly to dextrose and dried in a vacuum between each addition. This mixture of dried powdered whole blood and dextrose has been put into solution and given to humans by the intravenous route for the treatment of anemia, both acute and chronic. With use of the larger doses, hemoglobinuria "occurred with no harm." 11 M-AB RESTRICTED ENCLOSURE (A), continued VI, Describing preparation of "powder colloid of bacteria" and its anti- gonic properties. Bacteria disintegrated by various procedure such as freez- ing and crushing, "colloid mill method" "Weimarus" method and the supersonic wave method, are dispersed on the surface of dextrose crystals in the same amount to dextrose powder, thorough mixing, drying in a vacuum and repetition of the same process. The preparations are readily soluble in water, forming "typical milky turbid suspended solutions". It is claimed that studies in both humans and animal a show the preparations to be more antigenic and less toxic than bacter- ial emulsions. Also the dry powder is more stable than the usual liquid prep- arations , Samples of these preparations are being forwarded under separate cover. TOKYO IMPERIAL UNIVERSITY Government Institute for Infectious Disease Prof. Yoneji Miyagawa and Staff I. Vaccine - Japanese B Encephalitis (Kltsoka) Vaccine consists of 10$ of 0,2$ formolinized (suspension) of mouse brain, (in saline). Two subsutaneous injections of 0,8 and 1.0 cc are given. One thousand individuals in test area vaccinated. However, no outbreak occurred so no human evaluation was possible. Serum from a greater portion of those vaccinated showed 1.000 or 10,000 neutralizing antibodies (per cc), (Neutralizing antibodies against 1.000 to 10,000 M.L.D. of virus). Vaccine standardization: Three doses of vaccine 0.3, 0.5, and 1,0 cc given to 20 gram mice at five day intervals. Two weeks later mice resist 100 or 1000 intracerebral doses, (of virus?) Five-tenths cc of serum from vaccinated individuals inoculated subcutane- ously protects mouse 12 days later against 100 or 1000 intracerebral doses. Monkeys receiving 10 cc similarly protected in five days. 11. Epidemiology of Japanese B, encephalitis, Kitaoka (1938) Tokyo Iji Shinshi (weekly medical journal) reports isola- tion of virus in the field from culex popiens var, pallens and aedes albopie- tus. Anopheles sinensis found on laboratory experimentation to be a vector. Tranovarian transmission was noted. In regions where disease provalent-antibodies were found in a '’normal" man (80-90$), dog and pigs (85$), horses (98$), cattle (88$). These observa- tions were in the Tokyo area. Sera from Hokkaido was negative. Sera from Kobe and Osaka showed a lower percentage of positives. The percentile differ- ence showed a relation also to mosquito incidence. Active infection has not been noted in horses and cattle. 111. Dengue. Claims for the isolation of a phenol susceptible dengue virus, some years ago, with the same filtration size as the yellow fever virus have been made. A sample of this virus is to be forwarded under separate cover. 12 RESTRICTED M-AB ENCLOSURE (A), continued Japanese studies with this virus showed no difference between it and the Java and Malayan strains. A strain of dengue virus, isolated in 1943 by injecting patients whole blood intra cerebrally into mice, is now in its 200 th mouse transfer. (With this virus) two to three percent of mice show paralysis two to three weeks after injection (no encephalitis). Thirty-five hundredth co of a 10$ emulsion of the brain from the tenth mouse passage Inoculated subcutaneously into humans, caused fever (39°) in 11 days that lasted for five days, A maculopapular rash lasting 20 hours appear- ed 13 days post-inoculation. Patients serum 12 days after illness, produced (?) encephalitis in 100$ of the injected mice. Patients serum three weeks after inoculation neutralized mouse virus. The potency of the virus is con- stant between 10-4 (.0001 cc) to 10-5.5 (.00005 cc). One experiment on human vaccination with 10$ of a 0,25$ formolinized mouse brain suspension (in saline) given in three doses of 0.5 cc, 0.8 cc, and 1,0 cc at weekly intervals, protected against 0.2 cc and 0.7 cc subcutaneous injections of infected human serum. The animal came down with a typical case of dengue. TOKYO IMPERIAL UNIVERSITY Government Institute for Infectious Disease Acute Liver Necrosis Due to Infection of Shellfish (Oysters and Mussels) Toxin has been extracted from liver of the poisonous mussels and oysters by Dr. Akiba (Bacteriology Department of Tokyo Imperial University). It is water and alcohol soluble and thermostable. Immune responses were not studied. Toxin injected into mouse, cat, dog, rabbit, reproduced hepatic lesion; not in rat. Cause of rat resistance not known. Transplantation of normal mussels and oysters to affected regions of spring induced toxic properties; conversely toxic shellfish, transplanted to other regions, lost their toxic properties after a few weeks. Studies of plankton, in affected regions, were unreward- ing. Reprints on the pathology and clinical findings are attached. TOKYO IMPERIAL UNIVERSITY Government Institute of Infectious Disease The Action of Immune Serum on the Japanese Encephalitis Virus Cultivated in Vitro Yoshio Kawakita A "so-called” Immune Horse Serum prepared by inoculation with 10$ mouse brain virus (Strain Kalinina isolated in 1935) over a period of five months, a total of approximately 2,230 cc was injected, inactivated virus in vitro and protected mice (8 to 10 gm) in a dilution of 1-10,000. (100 M. L. D.). The Immune Serum also inactivated the virus in a culture flask - after 24 to 48 hours Incubation at 35 #C. Virus cultivated in chick embryo (9 day old) were likewise inactivated by the Immune Serum. (0,3 co of serum in 2.7 co Tyrodes solution inoculated with one drop of infected chick brain tissue.) 13 M-AB RESTRICTED ENCLOSURE (A), continued The possibility of serum therapy in Japanese encephalitis is indicated. No human experimentation is reported. TOKYO IMPERIAL UNIVERSITY Government Institute for Infectious Disease Infectious Hepatitis Virus Isolation and Cultivation Dr. Masami Kitaoka Experiments were conducted involving numerous animals and techniques which resulted with claims for the isolation of the virus and mouse infection (subolinioally) with transmission from generation to generation. This virus appears to be about the size of the herpes virus. The active agent produced some degree of immunity in mice, and the neutralizing antibody was detected in the sera of human convalescents. This new virus does not belong to the spon- taneous pneumo-tropic mouse viruses, nor has immunological relation to the influenza-A-virus through cross immunity tests. Cultivation of the virus in fertile eggs is claimed. Good-pasture Tech- nique is utilized. TOKYO IMPERIAL UNIVERSITY Government Institute for Infectious Disease Dysentery of Unknown Etiology Occurring on Shikoku Dr. S. Kojina Dr. Kojima is an authority on Enteric infections and Director of The International Salmonella Center for Japan. Recently several new species of Salmonellae have been isolated in his laboratory. Cultures of these are being obtained. The new species were not isolated in conjunction with any large outbreaks of disease but were from individual cases. Questioned concerning dysentery, whooping cough and gonorrhea vaccines, Dr. Kojlma did not consider them very effective. Concerning Influenza vac- cination, he felt that the Japanese vaccine was effective for three months. He has an "A" influenza virus but his "B" virus is no longer viable. A cul- ture of the "A” virus was requested from him. He in turn would like to pro- cure the "B”. An epidemic of dysentery of unknown etiology that first occurred in Taka- mat su-Kagawa Prefecture, Shikoku Island was thoroughly discussed. The disease has only been encountered on the one island and there only in the one prefec- ture and in that mainly in the city and towns surrounding Takamatsu. The dis- ease first was brought to his attention in 1944, at which time there were 4,000 cases, with a 30% mortality. In 1945 there were 3,000 cases, with a 20% mortality. The disease is most prevalent from June to October, though oases occur up into December. Clinically, the disease is like Shiga Dysentery, and exhibits the follow- ing symptoms: Tenesmus, frequent stools OO to 100 per day); stool bloody with mucous; severe headache; coated tongue; loss of appetite; fever, as high as 103; onset sudden; the incidence by age groups is high - in children under 10 and in the group over 30. A typical curve would be as follows: Incidence: Age 10 20 30 14 RESTRICTED M-AB ENCLOSURE I A), continued The course of the disease is severe in children and in the older groups. Mild oases occurring and not being reported in the middle aged group, may account for the curve presented. The duration is from one week to ten days. Those with the severe type infection die within 10 days. Shigella shiga was not isolated from any patients. However, a paracolon- like organism, now called the "Obayashi strain", was isolated from 20 pa- tients, This organism is agglutinated by the patients serum in a dilution of 1 - 800. Shiga and Flerner strains, of known origin, are agglutinated only in the low dilutions of sera (1 - 100.), The Obayashi strain is considered as the possible etiological agent, by the above. Cultures of this strain are being procurred. In therapy an oral vaccine, prepared with this strain, was tried in a few instances without success. A limited amount of sulfaquanidlne, available and used, seemed to be effective. However, insufficient drug did not permit large scale use. 11. TOKYO IMPERIAL UNIVERSITY MEDICAL COLLEGE Institute of Pharmacology and Pharmacy Pathology Department, Serology Section Brain Research Institute Opthalmology Department Division of Physiotherapy and Internal Medicine TOKYO IMPERIAL UNIVERSITY MEDICAL CQLI3SGE Institute of Pharmacology and Pharmacy Head by Prof. Kenzo Tamura Associates; Prof. Ryotaro Asuma, Morizo Ishidate, Yoshito Kobayashi, and Kikuji Chikita The last five years, due to limited laboratory equipment and supplies, very little new research was conducted. The following subjects were studied; Digioorin: A glucozide of Digitalis isolated and structure determined by Tamura, Ishidate, Kobayshi and Tokita. Use: Cardiac stimulant Action: Less toxic than digitalis Reprints and samples attached. Vitacamphor: "P-oxocamphor" Synthesized by: Tamura, Kihara, Ishidate Use:4 Cardiac stimulant Action: That of stimulation Reprints and samples attached. 15 M-AB RESTRICTED ENCLOSURE (A), continued Bufotalis: "Senao” Extracted by Kobayashi Use: Cardiac stimulant Reprints attached. Estrogenic substances and Pituitary preparations. Reprints attached. Copy of Japanese Pharmacopoeia is being forwarded under separate cover. TOKYO IMPERIAL UNIVERSITY MEDICAL COLLEGE Pathology Department, Serology Section DrT Tomio Ogata I. ’’Communin’1, a new drug studied by Dr. Ogata is of bacterial origin and used in the treatment of pyogenic infections and eczema. The clinical use of bacterial filtrate was suggested by the fact that small doses of such filtrates will inhibit the Shwartzman phenomenon and Dr. Ogata believes the active substance producing the Shwartzman phenomenon stim- ulates the reticulo-endothelial cells to produce a substance harmful to bac- teria. The preparation of the filtrate is as follows, B. Coli are grown on Agar plates for 20 hours and washed off with saline. The Saline suspension is cen- trifuged and the supernate filtered through a Sietz or Berkefeld filtre. This concentrated filtrate is diluted about 100 times and given in one oc subcutan- eous injections daily for three to seven days. Approximately 1,000 patients have been treated with good clinical results and there are case protocols on about 300 cases. Dr. Ogata believes the saline material is a carbohydrate and he and his associates are working on its isolation. Attached is reprint with a local translation of same and one vial of the drug. Reference is made to Journal of Experimental Medicine, Jan, 1, 1936, Vol, 63, No. 1, page $9-68, Inhibition of the Shwartzman Phenomena, by Tomio Ogata, M.D. 11, Studies on the Precipiton Reaction are also undertaken in the Serol- ogy Section. Attached is a reprint on same. TOKYO IMPERIAL UNIVERSITY MEDICAL COLLEGE Brain Research Institute This institute appears to be a very loose knit affair; an institute in name only. It is directed by the professor of psychiatry, Dr. Yushi Uohimura. Research work is divided into three fields - Anatomy, psychology, and hereditary Biology. The pyschiatry and neurosurgical wards of the University Hospital afford clinical material in connection with projects of the insti- tute, Current projects are: 16 RESTRICTED M-AB ENCLOSURE (A), continued Effects of the Atomic bomb on the Brain and Nervous System. Electroencepholographery studies on epileptics, on effects of drugs on the brain, and comparative studies of waking and sleeping states. Mental development of twins. Histology of the brains of genius. TOKYO IMPERIAL UNIVERSITY MEDICAL COLLEGE Opthalmology Department Projects for Improvement of Vision (National Research Council) Prof. Yoshiharu Shoji The major objectives and accomplishments of the National Research Council program are summarized in the attached reports submitted by Dr. Shoji, Ac- cording to Dr./Shoji the myopia problem in Japan involves 15% of the popula- tion. Within this group about 20% have a myopia of three diopters or more and these are all due to elongated eyeballs and are incurable. Eighty percent have a myopia of less than three diopters and among this group one in five is due to spasm of accomodation which can be alleviated by atropine. At present fewer people are developing myopia and this is related apparently to the fact that there have been fewer students doing close work. Professor Nakejima has been working with a hormone known as ’’melanophoren hormon" which is said to improve night vision in humans. Under separate cover, three books and a set of reprints representing the the work of Dr. Shoji, are being forwarded. TOKYO IMPERIAL UNIVERSITY MEDICAL COLLEGE Division of Physiotherapy and Internal Medicine Prof. Takayoshi Misawa Investigations were conducted on allergic diseases and hot springs thera- py, There is very little hay fever in Japan, probably due to lack of wind- blown hay fever producing pollen. There is no ragweed pollen. Food allergy is not uncommon and the most common allergy producing foods in Japan were Egg- plant, Bamboo sprouts, spinach, sea fish and buckwheat. Prof. Mi-sawa be- lieves the histamine content of their foods is the cause of their producing allergic symptoms. Treatment used is Vitamin D and Calcium Salt therapy. Injection treat- ment with antigens is not used, but Histamine injections are thought to bene- ficial. Reprints of Dr. Misawa’s research work, published since 1940, are for- warded under separate cover. 17 M- A B RESTRICTED ENCLOSURE (A), continued 111. TOKYO ARMY MEDICAL COLLEGE Clinical Division Biologic Manufacturing Division Parasitology Section Physical and Chemical Laboratory Penicillin Research Committee Manufacturing Division, Niigata Department of Pharmacology Kanazawa Branch Field Manuals Research Projects and Findings (Enclosure (B), this report) Organization of Japanese Army Medical Department (Enclosure (C), this report) TOKYO ARMY MEDICAL COLLEGE Clinical Division Chief of Surgery - Colonel Nagaw (Mayo 1935-1936) Surgery is done according to accepted procedures and no new techniques have been devised. There has been no experimental or clinical research of im- portance or of an original nature. Opthalmology - Colonel Yagamoto Original work carried out during the war consisted of studies of color perception and extending the work of Ishahara by development of a new color chart for the detection of fatigue in color vision. Some work has been done on the use of the color blind to detect camouflage. Some thought has been given to the development of the so-called "6th sense" in the blind. Maxilo-facial surgery - Lt, Col. Matsuki Plastic surgery - Col• Toda Urology and dermatology - Col. Tanahashi Radiology - Maj. Misanou Internal Medicine - Col, Hirobunii Osuzu The department of internal medicine has been working mostly on clinical research in tuberculosis and in carrier detections in typhoid fever. No sig- nificant research has been conducted. Orthopaedic Surgery - Col. K. Takigawa Battle fractures are handled by skeletal wire traction and casting with windows. Wounds are left open and not packed. Secondary suture is used in suitable cases. 18 RESTRICTED M-AB ENCLOSURE (A), continued Department of Neuro-Psychiatry - Col, Keisaburo Suwa Located in separate building, called the "Konodai Insane Hosptial". Bed capacity about 700. Patients mostly psychotics with a few war neuroses and organic neurological cases, including brain injuries. It is worth mentioning that paresis accounts for only five percent of admissions as contrasted with 19$ in civilian mental hospitals. Treatment was being carried out along the line of accepted principles. Careful records and statistics were being kept but there were no research projects worthy of note. TOKYO ARMY MEDICAL COLLEGE Biologic Manufacturing Division Director: Col Inouye Due to destruction of the buildings, this section has moved its plants to Niigata and Kyoto. However, Col. Inouye and part of his staff remained in Tokyo. Vaccines used in Japanese Army are: {innoculations are given as indicat- ed below) Typhoid, paratyphoid A, paratyphoid B - Mixed - routine Smallpox - routine Typhoid - Control measure in face of an outbreak Paratyphoid A - Control measure in face of an outbreak Paratyphoid B - Control measure in face of an outbreak Cholera - Control measure in face of an outbreak Plague - Control measure in face of an outbreak Meningitis - Control measure in face of an outbreak Typhus - Control measure in face of an outbreak BCG - to all tuberculin negative soldiers Tetanus - Toxoid in experimental stage Gas Gangrene - Toxoid in experimental stage Cholera strains used were three isolated recently from an outbreak in Shanghai, Plague cultures were isolated from four human cases in Burma and Manchuria. Tlje BCG immunization program has been in effect since 1942. Approximate- ly 20-30$ of all men joining the Army received BCG. In 1945, the vaccines were prepared in a dry form to prolong their poten- cy. They never came into practical use. Vaccines were manufactured in Japan, Manchuria, North China, South China and Singapore, Procedures employed in producing vaccines are attached. Visits of the Niigata and Kyoto plants are anticipated. 19 M-AB RESTRICTED ENCLOSURE (A), continued TOKYO ARMY MEDICAL COLIEGE Parasitology Section Dr. H. Osuzu Very little research work has been done on parasitic disease. The fol- lowing subjects were studied; Fllarlosls; Treatment of cases of heniatoohluria with colloidal antimony plus oral administration of picric acid. Good results reported. Complement Fixation Reactions in Malaria; Specific antigens for P. Vivax, P. Malarial and P, Falicparun are prepared from the paasmodia obtained from human cases. Antigen prepared in an Na OH solution and left at ice box temperature - good for one week. Claim test is specific with no cross react- ions. Treatment of Malaria; Sheet attached. These subjects are covered in "A new Book on Tropical Medicine”, edited by Prof. Dr. Miyagawa, 1945, which is being forwarded under separate cover. TOKYO ARMY MEDICAL COLLEGE Physical and Chemical Laboratory Director: Col. Goro Tatsui Assistant; Major Yoshikaru Yamoshina The laboratory equipment in general is very poor. This laboratory is primarily a control lab for the Japanese Army. Rou- tine tests are made on water, milk and all drugs and chemicals bought by the Army for their use. Very little research is done. The attached report indicates some syntheses attempted in the laboratory. None of this-material has been tried clinically. A copy of Japanese Army Pharmacopoeia will be forwarded under separate cover. TOKYO ARMY MEDICAL COLLEGE Penicillin Research Committee This committee was organized in February 1944 and its Direction appears to come from the Army Medical College. Outstanding Japanese scientists from many fields are associated with it. i The Nagao Institute did most of the original culture work. Where more than 1000 strains of P. Notatum were isolated, 11 of these were productive. Two strains (#233 and 176) have been utilized. Total commercial production was reputedly 1500 gms, of finished penicillin per month with smaller aiaounts produced in research laboratories and some crude local production in other places. 20 RESTRICTED M-AB ENCLOSURE (A), continued Commercial production is done in the Morinaga plant at Mishina (capacity 1000 gm. per month). The finished product is crude according to our stand- ards. Attached are photographs of the Mishina plant and a local translation of a report on research and production by Dr. H, Umezawa. TOKYO ARMY MEDICAL COLLEGE Manufacturing Division, Niigata An alum precipitated polyvalent toxoid-containing V. septique Cl, histo- lytica, Cl. wolchii, Cl, noryii may have some merit. Report of this work in reprints to be submitted upon receipt by this committee. Gas Gangrene Vaccine The attached formulae was furnished this office by the Japanese in lieu of the original reports which have been sought but not secured. Also attached is formulae for preparing Tetanus vaccine. TOKYO ARMY MEDICAL COLLEGE Department of Pharmacology Col. G, Tatsui Insect Repellents Worked on the production of D.D.T, Less than one kilo was prepared due to shortage of chlorine and benzene. It was found very effective against lice, but only sufficient quantity was available for experimental purposes. Information, of use of D.D.T. by the American Army, was obtained thru News Agency from Germany in August, 1944, when Germans discovered it was being used on the skin of war prisoners. Prof. 0. Kaburaki and Prof. H. Mori at the Agricultural Department of Im- perial University, prepared a small amount (a few hundred grams) with which the Navy experimented. The medical department employed pyrethrium as the main insecticide, Dor- ris was not available to any great extent. The repellents used were Lemon grass oil, Citronella and a mixture of Benzopheriene and Thymol, which were found very effective against mosquitos. Paris green and a non-arsenic compound Ferric Arsen were used against mosquito larva. Attached is a summary of research on Synthesis of D.D.T. 21 M-AB RESTRICTED ENCLOSURE (A), continued TOKYO ARMY MEDICAL COLLEGE Kanazawa Branch Director: Dr. M. Yabe The use of B.C.G. in the Army and the preparation of a better B.C.G. has been the prime duty of the above in his connection with t he Army. Reprints of data have been procurred. Further data is to be submitted by mail. These items will be forwarded under separate cover. TOKYO ARMY MEDICAL COLLEGE Field Manuals Manuals for distribution to Japanese medical officers, staff officers and enlisted personnel, dealing with the subjects listed below, have been col- lected and delivered to A.T.1.5., GHQ, AFPAC, for translation and forwarding: 1. Bacteriological examination methods for contagious diseases and for food poisoning. 2. Methods for inspecting meat. 3. Immunizations, 4. Field medicine. 5. Unit dental care handbook for medical officers. 6. Tropical hygiene and sanitation, 7. Psychiatric examinations. 8. Chemical Warfare detection methods. 9. Toxicologic examinations. 10. Sanitation and hygiene in cold areas. TOKYO AHMY MEDICAL COLLEGE Research Projects and Findings Attached (see Enclosure (B) of this report) is a list of the research projects of the Japanese Army Medical College and an English summary of the findings. Reference is made to the report on Wartime Research Commission, Section XXX. 22 RESTRICTED M-AB ENCLOSURE (A), continued TOKYO ARMY MEDICAL COLLEGE Organization of Japanese Army Medical Department Attached (see Enclosure (C) of this report) is information from the CG, Japanese Army Medical College on: 1. Total number of doctors, scientists, nurses and other officers and enlisted personnel. 2. Total number of hospital, laboratories and other fixed and mobile units. 3. Distribution of medical personnel and units in Japan and in occupied areas, 4. Medical education, before and during war, in the Army. $. Tables of organization and equipment and of medical units. 6. Lists of casualties during the war, with breakdown as to cause and effect. and the curriculum of civilian medical schools before and during the wax, for doctors, dentists and nurses. Answers to questions 2, 3, and 4 are in the process of translation and will be forwarded under separate cover. IV. KEIO UNIVERSITY MEDICAL COLLEGE Chemistry Department Department of Parasitology Anatomy Department Journal of the Faculty KEIO UNIVERSITY MEDICAL COLLEGE Chemistry Department Director. Dr. Yojl Sueyoshi Main investigations carried out on Transformation of carbohydrates from fats, on coagulation of blood, and on Vitamin and nutrition studies. Laboratories were destroyed during the war. Attached are reprints of recent research work. Importance of Linollc acid in Nutrition 23 M-AB RESTRICTED ENCLOSURE (A), continued C - Ajitaminuse Transformation of Carbohydrate from fats Blood Coagulation Miscellaneous KEIO UNIVERSITY MEDICAL COLLEGE Department of Parasitology Prof. Dr. T. Koizumi Dr. Koizumi and associates have done most of their work for the past 14 years on the properties of the toxic substances of Ascaris, Subject covered were; Ascariosis: Collected papers on this subject being forwarded under separate cover. Provocative Measures in Malaria; It was stated that stivisan is very ef- fective in bringing malaria parasites into the peripheral circulation. Much better adrenalin. Fever Therapy in Paretics: Plasmodium ovole utilized. Stated to be more effective than P. vlvax or P. malarial. Also easier to control and to effect a cure of the malaria infection. KEIO UNIVERSITY MEDICAL COLLEGE Anatomy Department - "Okajlmas Folia Anatomlca Japonica" The attached is a catalogue of the volumes of this journal published since April 1941. Journals are being forwarded under separate cover. KEIO UNIVERSITY MEDICAL COLLEGE Journal of the Faculty - "Keio Igaku" The attached is a catalog of the volumes of this journal published since December 1940 issue. Publication was discontinued after the April 1943 issue. The journals are being forwarded under separate cover. 24 RESTRICTED M-AB ENCLOSURE (A), continued V. OKUBA ARMY EXPERIMENTAL STATION General Information Medical Section OKUBA ARMY EXPERIMENTAL STATION General Information This is an Ordnance installation; however, it appears that ordnance was an overall Technical service to the Japanese. This station is divided physically and by fields of work. For instance, ffb Section is CWS (Screened by CWS representatives), #7 Section is Medical. Its delegated function pertains to weapons relating to physics. The director is Major General Matsusaki (Medical). As a sideline Gen. Matsusaki was inter- ested in increasing the individuals vigor and sensual acuity. It is reported by other Japanese that he accomplished little. Reference is made to Appendix "A", Section V. #lO Section is Shipbuilding, There was a medical staff but it is report- ed that it accomplished nothing. These are the only sections having medical groups. Weapons pertaining to physics have been reported upon by the Scientific Intelligence Survey. OKUBA ARMY EXPERIMENTAL STATION Medical Section Presentation of work by Surgeon Major General Matsusaki and staff. The only subject of interest was "Neocyamine". This chemical is employed in photography as sensitizing agent to infra- red, The basic idea advanced by General Matsusaki et. al. is that if more infra-red rays can be brought into the body a beneficial effect will be pro- duced. They have administered neocyamine to experimental animals and to ap- proximately one million humans. It is claimed that the drug is beneficial in the treatment of frost bit, uninfected and infected wounds, carbuncles, ery- sipelas, pyemia, burns, tuberculosis, lymphademltis, and leprosy. The drug is known here as Koha A (Neocyamine). Approximately 300 chemi- cal derivatives have been prepared. Of these about 100 have been tested in animals. Koha A is reportedly non-toxic. The usual dose is one or two ta- blets by mouth daily or two cc (0,3 mg) of a solution intravenously. A number of laboratory and clinical reports were submitted in support of the claims made. Most striking are the claims for the successful treatment of the leprosy. Among 371 lepers treated 81$ were said to have shown evidence of improvement. A lengthy series of photographs to support the claim were pre- sented. Attached are reports in Japanese script concerning Koha A. Samples of the drug are forwarded under separate cover. 25 M-AB RESTRICTED ENCLOSURE (A), continued VI. KITASATO INSTITUTE FOR INFECTIOUS DISEASE, TOKYO KITASATO INSTITUTE FOR INFECTIOUS DISEASE, TOKYO Director: Dr. T. Kitashima Assistants: R. Kobayshi, Bacteriology; Y. Kusana, Preventive Medicine; K. Nagano, Parasitology; Y. Watanabe, Bacteriology 1. Bacteriology Principal research work has been done on Tuberculosis, Leprosy, Typhoid and Para Typhoid Fever, and Dysentery, Work on Tuberculosis has been chiefly differential studies on bovine, human and attenuated strains. Leprosy studies have been on the pathogenicity and transmission based upon Watanabe’s "so- called" filterable rat strain. Typhoid and paratyphoid studies have been on prophylaxis, attenuate strains for vaccination and innooulation versus oral vaccination. Dysentery studies were on prophylaxis, oral vaccination, and differentation. 2, Parasitology Very little research has been done in the last 10 years. Concerning schistosomiasis, the cow is the most important resevolr host and is more important than man in the transmission of S, Japonicum. Lime nitrogen has been found effective in the control of snails. Concerning mosquito control, the breeding of Aedes Albopictus in pools in Tokyo Area has been controlled by means of a minnow Oryaius Latlpus, Attached is a list of studies published during the last five years. Archives of the institute since 1940 will be forwarded under separate cover. It appears that such eminence as this institute once had is rapidly fad- ing into the past. VII. INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH Physiological Chemistry and Nutrition INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH Physiological Chemistry and Nutrition Ur. Waro Nakahara (From a report, Chemical Research carried out at the Institute of pysical and Chemical Research, dated 25 September, 1945, of Scientific Intelligence Sec- tion GHQ, AFPAC.) 26 RESTRICTED M-AB ENCLOSURE (A), continued No military research was carried out. Dr. Nakahara stated that he had discovered a new specific dietary re- quirement; a lactation factor made up of two constituents, one an adenylic acid compound and the other, peculiarly enough, or the,amino benzoic acid. Estimate by the interrogating officer was that Dr. Nakahara was a scien- tist of high order and truthful. VIII. TOKYO MUNICIPAL HYGIENIC LABORATORY Bacteriological Laboratory TOKYO MUNICIPAL HYGIENIC LABORATORY Bacteriological Laboratory 1. Hygenic laboratory and director Dr. Fusao Ishiwara, is a governmental and municipal institution serving public agencies, physicians, and private citizens. It is divided into four sections - one for water analysis, an one for food analysis, another for clinical analysis including X-ray, and the other chemical analysis. Production of biologies is limited to diptheria toxoid and dried plasma. Laboratory appears to be in a "rundown" condition. 2. Bacteriological Laboratory, directed by Dr, S. Kanno, is a governmen- tal and municipal institution which prepares biologies and conducts surveys. Typhoid, Typhoid Para Typhoid A and B, Cholera, and Dysentery vaccines were prepared. Surveys for carriers of Typhoid, Para Typhoid A and B, Dysentery, Cholera, Diptheria, Meningicocoi, and Plague were carried out. Research work was unimportant. DC. TOKYO NAVAL MEDICAL COLLEGE Organization Preventive Medicine Department of Pharmacy 27 M-AB RESTRICTED ENCLOSURE (A), continued TOKYO NAVAL MEDICAL COLLEGE Organization Director; Vice Admiral Y, Kanbayasi Research Organ, Kenkyubu in Naval Medical College was established in Autumn, 1943. Object. The study of the medical science and pharmacology which is necessary for the sanitation and hygiene of the navy. Organization. Chief of research. Surgeon Rear Admiral Osuka, Kanai, Yokokura. Staff of general affairs. Surgeon Commander Watanabe, Ota. Section Department Head Number of members System of Education Surgeon Capt, Yoshida, Murakama 3 Medicine S, Cap, Kanai, Arlga 3 Surgery S. Cap, Tomita 2 Oto-rhlno-pharyngology S. Gap. Nakamura, Yoshida Opthalmology S. Cap. Funakawa, Comm. Tanaka Dermatology S, Comm, Nakauchi Roentogenology S, Rear Adm. Yokokura, Comm. Norioka Bacteriology S, Cap. Miyao, Arima, Kawai, Comm. Hatakeyarns 6 Hygiene S, Comm, Kiyohara, Toda, Nakamura 4 Pathology S, Cap. Murakami, Comm. Ota 1 Pharmacology S, Cap, Murahara 4 Departments. Plan of Study At the beginning of the financial year each departmental head makes a plan over the thesis of the practical studies; viz; Sanitation and hygiene of the Navy, Prevention and Treatment of sickness and wound, Prevention of gas casualties. Publication of the result of studies> (1) Kenkyubuho, Med, Journal 28 RESTRICTED M-AB (A), continued (2) Kaigun Gunikai Zasshi, Research record. It is claimed that records were destroyed. The preoeedlng is extracted from a local translation. Education in the Naval Medical College 1. Type of students (1) The surgeon education (I class - beginning course) six months. To educate young doctors, who graduated at a medical college in that year, basic naval medicine, (2) Education for chief surgeon (II class - junior course) six months. To educate the surgeon lieutenant, to become the chief surgeon of the naval ship. (2) Education of a special medical course. (11l class - senior course) two years. To educate a medical officer as a specialist. 2. Research at the college. (1) The department of research was established in the August 1943. Naval sanitation and hygiene were studies, (2) Classification of the studies. Infectious disease and paraslton disease in the tropic, prevention and treatment of the tuberculosis, battle wound, alrial hygiene and hygiene of the submarine were prin- cipal topics. (3) The results of Research. The results of these studies were publish- ed in the Kaigun Guniksi Zasshi, The proceeding is extracted from a local translation. TOKYO NAVAL MEDICAL COLLEGE Preventive! Medicine Surgeon Rear Admiral S. Yokokura, Associate Chief of Research (This report complements Appendix "A", Section IX of report covering period from 22 Sept, to 8 Oct. 45.) Navy personnel received the following vaccines as indicated: Typhoid, paratyphoid A, paratyphoid B - mixed Cholera Smallpox Diphtheria - anatoxin given to Schick positive young men BCG *- to all tuberculin negative men Tetanus - not routine - used antitoxin Typhus - mouse lung preparation - not routine Meningitis - used as a control measure Dysentery - oral vaccine of little value, if any The diseases regarded is most troublesome in the Navy were Meningitis and Dysentery. No satisfactory control method for Meningitis was followed; sul- fagumidine was of some use in the treatment of Dysentery. 29 M-AB RESTRICTED ENCLOSURE (A), continued Capt, Kawai denied any important research developments in the Navy Medi- cal College during the war. Attached are memoranda issued by the Japanese Navy Department for the control of contagious disease during the war. Of interest are the use of oral vaccine for Dysentery (admittedly ineffective) and the spread of epidemic typhus among naval personnel. Under separate cover copies of the following are being forwarded: a. Instructions given to Japanese Navy Medical Officers for the control of contagious disease. b. Copies of research publications from the Naval Medical College for the years 1940 - 1945. TOKYO NAVAL MEDICAL COLLEGE Department of Pharmacy Dr. Ryozo Hayashl, Lt, Comdr., Acting Chief Investigation of interest are: The preparation of a sodium hypochlocite solution by electrolysis. Re- print attached. Study of 2-Methoxy-6-chlor-9 (4-diethylamino-cyclohexyl-amino-acridin) as a substitute for atdbrine in the treatment of Malaria. Reprint attached. The preparation of drinking water from sea water by utilization of elec- tric charge of synthetic resin "Orgacid", At first Supply Depot (Naval Arsenal) work was accomplished in the use of pituitary gland extract from fish and cattle. Claims have been made that when this hormone is injected, it improves night vision. Reprint attached and sam- ple of drug under separate cover. Outline of training program in Pharmacy attached. X. TECHNICAL INTELLIGENCE TECHNICAL INTELLIGENCE (Accession list submitted in periodic reports) 30 RESTRICTED M-AB ENCLOSURE (A), conttnued XI. TOKYO INSTITUTE OF PUBLIC HEALTH Outline of Institute "Myopic Problem" Chemotherapeutic Institute, Ichikawa, Chiba TOKYO INSTITUTE OF PUBLIC HEALTH Outline of Institute Attached Is a general outline of this Institute giving its history, phys- ical installation, organization, staff, duties and responsibilities. TOKYO INSTITUTE OF PUBLIC HEALTH "Myopic Problem" Director; K. Nobeohi Dr. Ishikawa, Tomoyoshl (Physiologist) Member of Institute of Public Health within which is a "Committee for the study of the Myopic Problem" headed by Dr. Ishikawa, The committee was formed in 1939 to study five problems; I. Relation between myopia and constitution. 11. Influence of poor lighting on development of myopia. 111. Influence of general hygiene on myopia, IV. Hereditary factors in myopia. V. Nutritional factors in development of myopia. Kondo, Tadao (died 1944) opthalmologist did a great deal of work on the eye- sight problem. Much of his work was published and is in the attached journals and papers. Ishikawa (above) studied the effect of the various type characters and has shown that square type is less fatiguing than the cursive type. Attached are new Journals and Papers which deal with the problem. TOKYO INSTITUTE OF PUBLIC HEALTH Chemotherapeutic Institute, Ichikawa, Chiba Director; Dr. Shuji Hasegawa Secretary; Dr. Iwao Nishlmura Chief Attached Hospital: Dr. Sheichi Arifuku Outline of Activities of Institute is attached. The curative and preventive properties of Cepharanthin are outlined in the attached summary. It is claimed that this drug is effective in the treat- ment of leprosy, whooping cough, as well as Tuberculosis. Recent work has in- dicated its value in the treatment of allergic conditions, particularly Asth- ma. A summary of this more present work is also attached. Under separate cover is a book on the experiments carried out at the Institute, as well as samples of the drug. 31 M-AB RESTRICTED ENCLOSURE (A), continued XII. NAGAO INSTITUTE, TOKYO NAGAO INSTITUTE, TOKYO Director: Dr. Komiami Chemist: Dr. Yabata Ass't. Chemist: Dr. Hatsuta Botanist: Dr. Kawamura Manager; Mr. Okabo This is a commercially supported laboratory for maintaining fungus and yeast cultures for use in industrial fermentation processes. It appears to be modern, Abstracts of methods and research since 1940 is attached. Reference is made to Report Penicillin Research Committee attached to periodic report of 22 Sept. 45 to 8 Oct. 45 Appendix "A" Section 111, Attachments; Report on NAGAO Institute. The View of NAGAO Institute, The stock cultures at NAGAO Institute, The sorbose fermentation (II) by T. NEHIRA, at the NAGAO Institute. The sorbose fermentation (I) by T. NEHIRA, at the NAGAO Institute, The extraction of Flavin (Vitamin B2) from Elemotheslum. Ashbyii. R. OKABE, Y. HATSUTA, and 2, Veda, at the NAGAO Institute, XIII. CHIBA GOVERNMENT MEDICAL COLLEGE CHIBA GOVERNMENT MEDICAL COLIEGE Dean Koike Staff Associated With University; T. Seo, Prof, Surgery A. Minato, Prof, Pharmacological Chemistry K. Also, Prof. Hygiene K. Tanlkawa, Prof. Hygiene K, Sato, Prof. Dermatology and Syphology Y, Ito, Prof, Opthalmology S. Akamatsu, Prof. Biochemistry T. Takuma, Prof, Pediatrics H. Hazato, Prof, Bacteriology 7. Kagaya, Prof. Forensic Medicine Research Projects Include; Intra-arterial shook injection treatment by Seo, et al - sodium iodide, glucose, sulfonimidO, Sodium salicylate were injected in a variety of clinical diseases resulting in good reports. However, Specific results are questiona- ble. 32 RESTRICTED M-A8 SNCLOSVRS (A), continued Vitamin A extraction form subcutaneous fat of seals by MINATO yielding 180 International units per gram of fat. The liver contained only one third as much in contrast with whole liver. Preservation of meat and fish with a culture of B. Butyercus for one and one half years; however, the accompanying odors from the preserving agent has defeated the method for practical use. Research on penicillin has been carried out by TANIKAWA in connection with the Penicillin Research Committee. Reliable syphilis rates were secured from SATO which were higher than those in U.S. There has been no sensitivity to Atabrin encountered. Research on Enzymes has been done by AKAMATSU. Attachments: Results on 70 cases of intra-arterial shook injection treatment (Reprint in Japanese and English Summary). Penicillin Study. XI7. NIIGATA GOVERNMENT MEDICAL COLLEGE Cepharanthln Pathology (and Parasitology) Department Pathology Department Department of Biochemistry Clinical Division NIIGATA GOVERNMENT MEDICAL COLLECT Cepharanthln BrTTakashi Hashlmoto (Dermatologist) - Dean of School Extensive work was accomplished on the use of in skin T. 8.. particularly Lupus vulgaris, with prolonged remission or apparent cures. No definite results determined in its use in chest T.B. ”Cephaianthln” is an alkaloid of Wisteria Root grown in Formosa, It is manufactured by Kaken Selyaku Mfg. Co., Tokyo, under the supervision of Prof, Hasegawa of Institute for Infectious diseases, Tokyo, Raprint attached. Samples under separate cover. 33 M-AB RESTRICTED ENCLOSURE (A), continued NIIGATA GOVERNMENT MEDICAL COLLEGE Pathology (and Parasitology) Department Dr. T. Ito, Head of Department Dr. Ito serves in the capacity of pathologist and parasitologist. No parasitological research work has been conducted by him in the past few years. Clonorchlasls: A large Clonorchis area exists in Niigata prefecture but only a few clinical cases are new being seen. People are familiar with the infected fish and do not eat them, Paragonimasis: There are four rather restricted areas in Niigata prefec- ture ,ncameiy~TlT~lDiar-mura (Higashi Kubiki district), (2) Ookambara-mura (Na- kakambara district), (3) Nanatani-mura (Nakakambara district), (4) near Toka- machi (Nakauonuma district). Wet tissues of Paragenimus infected brain are being sent in under separate cover. NIIGATA GOVERNMENT MEDICAL COLLEGE Pathology Department Prof. T. Ito, Pathologist Prof. K, Akazaki, Pathologist The department has been praticularly interested in brain tumors and re- ticulum cell Sarcoma, Dr. Ito studied under Dr, Stevenson at New York Hospi- tal untill 1941. Approximately 100 autopsies and 300-400 surgical specimens are examined each year. Of this material about one half is received from the Medical School Hospital and the remainder from outside sources. Approximately l/ 4 of the cases examined at autopsy were tuberculosis and l/ 4 psychiatric, during 1944. Tsutsagamachi fever is indemic in this area. Publications were suspended in 1943 but prior papers and selected inter- esting autopsies were requested and will be submitted under separate cover. NIIGATA GOVERNMENT MEDICAL COLLEGE Department of Biochemistry Prof. N. Ariyama, Head of Department No research work was done during war, but before the war the department had 10 to 12 assistants. Prof. Ariyama spent two years at Washington University, St, Louis, study- ing with Dr. Shaffer and has been at his present post for 15 years. Prof, Ariyama claims to have isolated a blood forming substance from bone marrow. The work was done before the war, has not yet been published, since the starting material, marrow, was not abailable in Japan in sufficient quan- tity during the war. From over 100 kg. of fresh marrow, about a gram of mate- rial was isolated. Experimental aenemia, caused by bleeding in animals, is cured by a single injection of 0.1 mg. per kilo. He believes it stimulates the bone marrow. 34 RESTRICTED M-AB ENCLOSURE (A), continued The bone marrow is extracted by water of dilute alkali, and precipitated many times by alcohol and acetone, and color removed by bone black. The mate- rial, a white powder, is nitrogen free, produces reducing sugar on hydrolysis, part of which is fermentable, is dialyzable thru a semipermeable membrane and is thought to be a carbohydrate. It is non-toxic. Prof. Ariyama desires to repeat the isolation of the material and test its action on humans before pub- lishing, as insufficient pure material is available at present to complete the determination of the chemical structure. Attached is a summary of this work, prepared by Dr. Ariyama as a prelim- ary report for publication. Ten reprints from the department, published since 1940, are attached. Attachments: (TJ Biochemical studies on d-Ribose, with special reference to the mech- anism of Absorption of Sugars from Intestinal Tract. (2) Studies on N-Glycosides. Part 11. (3) Studies on N-Glycosides. Part I. (4) Studies on Metabolism of a-Ketonic Acids. (5) Studies on the Pasteur Reaction in Muscle. (6) Über Einen Inhabitor der Glyoxalase. (7) The Reactions of Sugars with Amino Acids under Mild Conditions. (8) Studies on Hydrolysis of Desoxyrlbo-Nucleotides and Nucleosiaes. (9) Precipitation of Nucleotides and Nucleosises with Salts of Heavy Metals. (10) Studies on Tumour Glycolysis, NIIGATA GOVERNMENT MEDICAL COLLEGE Clinical Division Department of Internal Medicine Prof. I. Shibata Investigated and published a report including the typing of pneumonia in Japan. (Reprint attached.) Studied the daily Vitamin B requirements on Japanese prisoners of war. Findings agree with American workers. Summary attached. Prof. Tasaka Conducted extensive studies on body temperature including influence of environmental temperature on cardiac and respiratory activity, on skin temper- ature of extremities and reaction of the body to fever in various diseases. Attached are summaries of unpublished work, on vitamin and temperature studies and the effect of acute hemmorage on velocity of blood flow. Department of Surgery - Prof. M. Nakata Department of Radiology - Prof. S, Nosaklo No research work has been done in these departments. 35 M AB RESTRICTED EECLOSURE (A), continued XV. TOHOKU IMPERIAL UNIVERSITY MEDICAL COLLEGE, SENDAI Department of Pathology Parasitology Department Bacteriology S. Osato Institute of Tuberculosis and Leprosy Institute of Tuberculosis and Leprosy (Investi- gation relating to Diabetes) Clinical Division Medico-Chemical Institute Pharmacology TOHOKU IMPERIAL UNIVERSITY MEDICAL COLIZGE, SENDAI Department of Pathology Dr. S, Nasu, Associate Prof, of Pathology Dr. T. Hoshida, Prof, of Pathology (absent in Tokyo) Dr. S. ISatsuoka, Neuro-pathologist Dr. S« Yatsuyanagl, Assistant Dr, Hoshida has been active in experimental research related to chemical Carcinogens. Special tissues including example of beri-beri heart was selected and will be forwarded under separate cover with department research project re- ports. TOHOKU IMPERIAL UNIVERSITY MEDICAL COLLEGE, SENDAI Parasitology Department Dr. £>. Nasu, Parasitologist Dr. S. Yotsuyanagi gives the lectures in parasitology at this school but was sick at the time. Dr. S. Nasu, a pathologist was interviewed. No parasi- tological research was being done at this school - only lectures to students. Paragonimiasis: Three cases of paragonimiasis in this institution in three years. Malaria: No malaria but five species of Anopheles in Niyaga prefecture. Glonorchlasls; Twenty years ago there was an area a little north of Sendai in which there were numerous cases of clonorchis infection. Infections were obtained from a small variety of carp, known as Funa, People discontinu- ed eating of this fish so tnat there are now practically no cases. Wet tis- sues on clonorchis cases are being sent in under separate cover. 36 RESTRICTED M-AB ENCLOSURE (A), continued TOHOKU IMPERIAL UNIVERSITY MEDICAL COLLEGE, SENDAI Bacteriology Masahiko Kuroya, Prof, of Bacteriology Working on the fractionation of E, typhi, by chemical means. Has isolat- ed a polysacchlride toxic fraction. Antigenicity undetermined beyond precipi- tin tests. Possible purpose of work, in nature of other fractionating work done, to use fractions for immunogenic purposes. Working on fractionation of T.B. (This latter completely covered in U.S.) Reprints of previous work are cataloged by title and will be forwarded under separate cover. Working on isolation of penlclllium notatum and preparation of penicil- lin. Teaches Bacteriology in the University, TOHOKU IMPERIAL UNIVERISTY MEDICAL COLLEGE, SENDAI Prof. S. Osato Dr. Osato has only recently Joined the staff of the Sendai School. Be- fore this, he was working in the Kanazawa Medical College and all of his pub- lished research work will be obtained in the journals of this college when they are collected. At present Dr. Osato is interested in the following: 1. Experimentally produced insomnia Animals which are kept awake to the point of exhaustion and death, can be kept alive several days longer than usual by the administra- tion of Vitamin B^. 2. The Effect of Hot Springs on the animal body When experimental animals are exposed to natural hot springs, the retioulo-ondothelial system of the subcutaneous tissues can be shown to have an increased phagocytic activity. 3* Treatment of Tuberculosis Dr. Osato observed more than 100 tuberculous patients showing all types of pulmonary involvement who were treated with oepharanthin. In his opinion, the treatment was either of no benefit or was injur- ious. He is now observing the effect of rhodinio acid on tuberculosis. This ten carbon chain acid comes from the bark of a tree commonly known as "Taiwan Shinokl" in Formosa. According to Dr, S. Katsura in Formosa the acid was effective in healing 20$ of patients with open tuberculosis. Dr. Osato states that the preparation has some value in the treatment of tuberculosis. The drug is irritant to the gas- tric mucosa and is dispensed in cod liver oil or some aromatic oil to offset this effect. It is given in a dose of 2-3 oo by month, every day for six months or more. 37 M-AB RESTRICTED ENCLOSURE (A), continued A specimen of the commercially prepared drug was secured and is being forwarded under separate cover. TOHQKU IMPERIAL UNIVERSITY MEDICAL COLLEGE, SENDAI Institute of Tuberculosis and Leprosy Director; Dr. Taizo Kumagai (also Pres, of Univ.) The Institute of Tuberculosis and Leprosy is housed in a new building donated by a private industry and completed in 1943. Although small, the In- stitute is modern in appearance and equipment. The staff, under Dr. Kumagai, is chiefly concerned with tuberculosis but leprosy is studied by Dr. Saburo Sato, whose work is mentioned below. Dr. Kumagai discussed several salient features of the tuberculosis prob- lem in Japan: 1. The peak death rate in Japan proper lies between the ages of 1$ to 25. Formosans, however, have a tuberculosis mortality curve of the same character as that of Americans, Dr. Kumagai points out that Japanese eat less fat than any other people in the world. He offers the opinion that the tuberculosis death rate in Japan is a reflection of the dietary habits of the people and he stresses the need for a high fat diet in treatment. 2. Twenty five years ago the tuberculosis death rate among rich Japanese was two and one-half times that among the poverty stricken masses. At present this situation is completely reversed and is related to industrialization of the nation. 3. Cepharanthin administered to both tuberculous animals and humans was of no value in the treatment of the disease in the experience of the staff of the Institute. Dr, Saburo Sato presented two findings of interest: 1. Koha A, referred to in a previous report under Okuba Experimental Station as a therapeutic agent for leprosy, was without value in the experience of Dr. Sato, who gave one milligram intravenously twice a week for six months to 60 lepers. 2. Dr. Sato had previously reported localized infections in chickens in- u ooulated with leprosy bacilli. During the war Dr. Sato demonstrated that by repeatedly inoculating excised and emulsified leprotic nod- ules from humans into the breast muscles of a chicken, a generalized formation of nodules containing acid fast bacilli resulted in six months, Reprints from the Institute are being forwarded under separate cover. TOHQKU IMPERIAL UNIVERSITY MEDICAL COLLEGE, SENDAI Institute of Tuberculosis and Leprosy (Investigation relating to Diabetes) Director; Dr. Taizo Kumagai In addition to the work on tuberculosis and leprosy which he directed and which is described in another report, Dr. Kumagai is also interested in dia- betes. He claims to have demonstrated the insulin effect of pancreas before 38 RESTRICTED M-AB ENCLOSURE (A), continued the work of Banting. He has since been interested In finding other substances which will lower the blood sugar level in diabetics. This year Dr. Kumagal presented to the Tohoku Medical Association his finding on a chemical which he extracted with other form the leaves of a plant specified as Sathyrus palustris L. var macranthus (white) Pornald. When this chemical is given by mouth to animals it lowers the blood sugar. Dr. Kumagal also gave it to 25 diabetics. In mild cases the blood sugar was lowered. In severe oases no effect was noted. A report was requested to be forwarded. TOHOKU IMPERIAL UNIVERSITY MEDICAL COLLEGE, SENDAI Clinical Division Y. Koga, Prof, of Radiology Dr. Koga is well known in Japan for having developed the Japanese use of photoroentgenography in mass chest surveys. Most of his work in this field was done before the war, particularly in 1938. During the war, his research activities were out down considerably by a great reduction in the size of his staff. His department has been working however, on research into: 1. Tissue culture methods 2. The effect of irradiation on tissue culture 3. Effect of irradiation on inflamatory lessions and on tumor cul- tures. General Surgery Prof. M. Muto. General Surgeon Prof. A. Katsure, Neurosurgery Clinical research has been done during the war. Dr. Muto has, together with his staff, worked on the surgery of Tuberculosis of the lung and on gas- tro intestinal operations for malignancy. Prof. Katsure and his staff have been working on the surgical aspects of epilepsy. They have done many pre and post operative electro-encephalograms. Prof. I, Mlki, orthopedist, has been conducting clinical investigations of chronic shoulder disorders. Reprints of all their papers since 1940 are being forwarded under separ- ate cover. However, none of the work seems important. Medical Department Dr. Toyojiro Kato, Prof, Emeritus of Medicine, 63, one of the leaders in Japanese medicine, retired in 1942 to direct the Institute of Aviation Medi- cine at Tohoku. Was founder of aviation medicine in Japan and has worked on the problems of aviation medicine for many years. The work of the Institute was done in cooperation with the military au- thorities and financed by the government. They have been working on the usual problems, using animals (dogs and rabbits). They have a large pressure cham- ber and a centrifugal apparatus and numerous laboratories for the study of blood chemistry. 39 M-AB RESTRICTED ENCLOSURE (A), continued Their work has been published, with the exception of the most recent in- vestigation in the Japanese Journal of Aviation Medicine, copies of which were obtained. (This info passed to ATIG.) Dr. F, Kurokawa, Prof, of Internal Medicine, specializes in gastro-enterology, is one of the best workers in this field in Japan and has published a text book (1936) on X-ray diagnosis in gastro-enterology. Is now wording on a study of the treatment of liver toxicities using levulose and Vitamin K, Has developed a micro method for liver glycogen determination. Reprints of all his published work were obtained including a review of Japanese gastro-enterology, published in 1943, which will be forwarded under separate cover. TOHOKU IMPERIAL UNIVERSITY MEDICAL COLLEGE, SENDAI Medico-Chemical Institute Director: Prof. H. Masamune Extensive studies of biological activity and structure of carbohydrates and the glycoproteins. More recent work on the isolation of a toxic glycidamine from human can- cer tissue, which is also believed a product of normal tissue. Structure not yet completely determined. Summary attached. Blood group substances have been isolated which are believed to be of carbohydrate nature related to chondridin. Attempts at the synthesis of blood group substances have been made. Summary attached. Attached are reprints of recent work as well as a summary of his carbo- hydrate chemistry given in 1943 before the Japanese Chemical Society. TOHOKU IMPERIAL. UNIVERSITY MEDICAL COLLEGE, SENDAI Pharmacology Motoo Terasaka, Prof, of Pharmacology Came to Sendai, March 1945, was previously Professor of Pharmacology at Nagasaki University of Medicine, where his research work was done. Research work on Pharmacology of Uterine Action, Effect of digitalis on the heart, Pharmacology of Ephedrine, and Chemotherapy of (bird) Malaria, and a study of the action of diphtheria toxin. Attached are 15 reprints of work published since 1941. (Suggest titles be translated and listed.) 40 RESTRICTED M-AB ENCLOSURE (A), continued XVI. HOKKAIDO IMPERIAL UNIVERSITY MEDICAL COLLEGE. SAPPORO Bacteriology Pharmacological Laboratory Bacteriology and Immunology Hygienic Laboratory Clinical Division Hot Springs Research Institute Pathology Department Biochemistry HOKKAIDO IMPERIAL UNIVERSITY MEDICAL COLLEGE, SAPPORO Bacteriology Yutaka Nakamura, Prof, of Bacteriology Complement Fixation Reactions in Malaria Tested 30 patients with induced P. vivax malaria. All cases were either positive or doubtful. Antigen prepared from human cells infected with P, vivax. Method of preparation being summarized and sent under separate Cover. HOKKAIDO IMPERIAL UNIVERSITY MEDICAL COLLEGE, SAPPORO Pharmacological Laboratory Prof, Takeo Masakl, Head of Department The following studies were conducted under his direction: Subjects of Investigation 1. Pharmacologic studies on Dihydrochavlbetol. Object To apply to medicinal purposes. Duration 1943 A substance similar to Gualacol and found less toxic than creosote. Pre- pared from Cinnamomum Camphora. Use: Abdominal disinfectant such as dyspepsia. Externally as skin disin- fectant. No clinical study made, laboratory studies only on rabbits and mice, and frog. Action; Similar to gualacol and less toxic. Incl: Reprints and sample. 2. Skin irritant action of the principles of peppermint oil. Rational use of pep- permint oil as skin irritant. 1943 Incl: Reprint of studies. 41 M-AB RESTRICTED ENCLOSURE (A), continued Subjects of Investigation 3. Skin Irritant action of the volatile oils and their principles. DDjeot To study the relation between the physico- chemical properties and the skin irritant effects. Duration 1943-1945 Result: The active principle of volatile oils causes the irrltantion. The more volatile an oil the more irritating. Physical proper- ties include the melting points, solubility and volatility. Volatility is essential for the skin irritation action. 4. The anthelmintic action of the principles of the pep- permint oil, especially of menthol. of peppermint oil as anthelmintic 1938-1943 Studies made on dogs, and oats found to be very effective. Found more effective than santonin. Large doses may be given and less toxic than santonin in large doses. Found 100# effective on Ascaris. 5. Action of drugs on louse. To study the mech- anism of louse-kill- ing action of drugs. 1944 Result: Essential Oils found effective, mixed with Boris Alba. This powder is found in Hokkaido, Talc may be used similarly, Boris Alba as a powder is found very porous, adding to its absorption properties. Use: Dusting powder. Inol: Reprint (Essential 011-25$ Sample; Lausan (Naphthalene-25$ (Boris Alba-50$ 6. Benzene-Naphthalene method, for the extermination of lice. Exterminate lice. 1944 Naphthalene in Benzene 25$ solution. Clothing sprayed and put in chest for 12 hours. Use: Spray, Most effective and convenient for use, Inol: Reprint 7. Comparison of the louse- killing effects of various evaporable substances. To study the relation between the physico- chemical properties and the louse killing effect. 1944-1945 Inol: Reprint. 8* Pharmacologic studies on Lucidusoulin, a principle of Aconitum Lusidusculum (Nakai) To study Its clinical applicability. 1940-1941 Study made on rabbits. No olinioal studies. Use: As an anti-diuretic Incl: Reprint 42 RESTRICTED M-AB ENCLOSURE (A), continued Subjects of Investigation 9. Pharmacologic studies on the diuretic principles of Stigmata Maydis. Object Valuation of stigmata maydis as a diuretic. Duration 1942-1943 Stigmata Maydis. is a powdered extract prepared from corn silk. Use: Diuretic, Being used in Europe, Incl: Reprint 10, The influence of quinine upon the function of ret- iculo-endothelial system. Research into the cause of the preventative effects of quinine on in- fection. (Respiratory) 1940-1942 Small doses stimulates, large doses acts as a depressant. Average dose: 0.003 - 0103 mg/Kg per OS Incl: Reprint 11, On the influence of the room temp, upon the quantity of urine in a whole day. To judge exactly the diuretic action of drugs on the rabbit. (Particularly Stigmata Maydis) 1942 High temp: Little diureses Low temp: Increase in diuresis. Constant temp: Necessary when studying action of diuretic drugs. Incl: Reprint Inolosures: Reprints 1, Pharmakologisehe Studien Über Dlhydroohavibetol. 2, Über die hautreizende Wirkung des Pfefferminzols. 3. Vergleiohende untersuohungen über die pharmakologisohen Elgenschaf- ten elniger Anthelminthika und der zur Terpenreihe gehenlgen Sub- stanzen; sowie Wurmabtrelbungsversuohe mittels Menthols an Hunden. 4. Action of various drugs on the louse. 3. Ueber eine neur "Benzol-Naphthalin" Methods zur Bekampfung der % Kleiderlaus. 6. Comparison of the louse-killing effects of the various evaporable substances. 7. Pharmacologic studies on Lucidusculin, a principle of aconitum lusidusoulum (Nakai). 8, Pharmocologic studies on the diuretic principles of stlgmate maydis, 9, The influence of quinine upon the function of reticuloendothelial system. 10, Study on the effect of room temperature upon the urine output in a day, 11. Manual on Drugs of Northern Japan (2). HOKKAIDO IMPERIAL UNIVERSITY MEDICAL COLLEGE t SAPPORO Bacteriology and Immunology Dr. Yutaka Nakamura, Prof, of Bacteriology and Immunology Has visited the United States twice, most recently in 1922, at which time he visited In Boston and New Orleans, following studies on Yellow Fever, under Rockefeller sponsorship, in a Japanese Colony in South America. 43 M-AB RESTRICTED ENCLOSURE (A), continued Primary interest is in Immunology and especially in Tissue Immunity (has the book of Kahn, "Tissue Immunity", but has not read same.) Recent research on viruses diseases (vaccinia) and rickettsial diseases. Claims that by cataphoresis an antigenic immunogenic protein fraction can be obtained from vaccinia. Claims that innoculation of blood of Tsutsugamushl patients testicularly into rabbits isolated virus which may be serially transfered, enhancing vir- ulence. Has applied cataphoretic studies to some members of the Salmonellae group especially gaertner’s bacillus and Sal enteritidis. Is working on penicillin Isolation of strains, A weak, impure product has been produced, experimentally. Research in general hampered by a lack of animals. Reports on work published in the journal of the university are to be for- warded separately. HOKKAIDO IMPERIAL UNIVERSITY MEDICAL COLLEGE, SAPPORO Hygienic Laboratory Dr. Zenjuro Inouye, Prof, of Hygiene Dr. Inouye has been primarily Interested in the physiological effects of air ions and has devoted much of the past 10 years to studying various phases of this problem. He has also been interested in the factors influencing the efficiency of the production of immunity by BCG Vaccine in guinea pigs. Some of his observations include the following: A. That the efficiency of BCG in protecting guinea pigs against human tubercle bacilli subsequently innoculated, is reduced in the presence of; 1. Low temperature 2. High temperature 3. Low atmospheric pressure 4. Malnutrition 5. Low calcium intake 6. Vitamin B^deficiency 7. Vitamin 0 deficiency 8. Fatigue 9. Acidosis B. That the efficiency of BOG is maintained or increased by; 1. Administration of Vitamin B^, 2. Exposure to an increased contratlon of air ions for short periods daily, C. That exposing factory workers to an increased concentration of air ions for short periods daily increases their efficiency and enhanced their re- covery from fatigue, A list of titles of research publications from the Hygienic Laboratory during the past five years in attached. A complete set of reprints has been furnished by Dr. Inouye and is being forwarded under separate cover. 44 RESTRICTED M-AB ENCLOSURE (A), continued HOKKAIDO IMPERIAL UNIVERSITY MEDICAL COLLEGE, SAPPORO Clinical Division Surgical Department - Prof. S, Yanaji A list of Investigations is attached. Psychiatry Department - Prof. T. Ishibashl Some research work was done during the war on the Aborigine Aimx, who are susceptable to the peculiar hysterias of primitive peoples, A list of publications is appended. Pediatrics Department - Dr, K, Nagl A list of publications is appended. Medicine Department - Dr, S. Nakagawa Experiment on the effect of cold on the bodies of man and animals, both in health and disease, have been conducted for the past 15 years without sig- nificant findings. Serological test and chemical test for malignaoy have been investigated for several years. Also, test on liver function have been done. A German drug, Benzylimidazolin, developed in 1941, a vogus stimulator, has been tested. List of publication also attached. Opthalmology Department - Dr. Sadami Ochi Principal work has been done on histopathologic studies of tracoma. Staining technique for inclusion bodies has been developed here. Procedure is described in the accompanying reprints. HOKKAIDO IMPERIAL UNIVERSITY MEDICAL COLLEGE, SAPPORO Hot Springs Research Institute Dr. S. Saeto, Medical Director Experimental work was done on the effect of mineral waters on wound heal- ing and also on intra-arterial injection of sterilized mineral water on dis- eases such as arthritis, and on acute and chronic infections. Good results were claimed. Reprints will be forwarded under separate cover. 45 M-AB RESTRICTED ENCLOSURE (A), continued HOKKAIDO IMPERIAL UNIVERSITY MEDICAL COLLEGE, SAPPORO Pathology Department Dr. I. Ken, Prof. Emeritus Dr. K. Takeda, Prof. First Pathology Department Dr. H, Ambo, Prof. Second Pathology Department Dr. K. Shimpo, Assistant Dr. K. Omata, Assistant Attached are reports of research projects undertaken by the two depart- ments of pathology at Hokkaido Imperial University, The high altitude studies will be reported in detail under separate cov- er. Tissues and abstracts of research projects and routine autopsies will be forwarded under separate cover. HOKKAIDO IMPERIAL UNIVERSITY MEDICAL COLLEGE, SAPPORO Biochemistry Prof. Biochemistry Morio Yasuda, M.D., Ph, D. (Came to Sapporo in 1942) Investigated metabolic and nutritional studies in connection with the Physical Culture Institute, Tokyo (Now closed). Investigated the structure of phorpholipids, particularly plasmalogen and amino acid kephalln derivatives. Recent reprints attached. A summary of more recent studies of the structure of phospholipids as well as nutritional and metabolic studies of inhabitants of cold regions as attached. XVir. HOKKAIDO IMPERIAL UNIVERSITY, SAPPORO * Veterinary Faculty Departments of Agriculture and Science Department of Agricultural Chemistry, Applied Mycology Cryological Institute HOKKAIDO IMPERIAL UNIVERSITY, SAPPORO Veterinary Faculty Prof. K. Ichikawa - Chief of Veterinary Medicine Dr, Ichikawa stated that Dr, Ono in Manchuria has developed a method of collecting Babesia parasites from blood. It is a sedimentation technic using calcium citrate (lOjfc) solution. The infected cells rise to the top, are pi- 46 RESTRICTED M-AB ENCLOSURE (A), continued petted off and sedimented two or three more times. Dr. Ichikawa said that it might be utilized in the concentration of malaria parasites. Dr. R. Kurosawa - Prof, of Obstetrical Veterinary Medicine Has done considerable work on the diagnosis of pregnancy in the horse. Published papers are being sent in under separate cover. Dr. S. Hamada - Bacteriologist in Veterinary Medicine Has done considerable work on Salmonella infectious producing abortion in cattle produced by Trichomonas, but upon treating cows with washings of Mercu- rochrome and Mercuric chloride, or a 0,5% solution of Lysol, this was prevent- ed. Dr. C. Kohanawa - Hematologist Dr. Kohanawa has done considerable work on infectous anemia in horses. He has also done hematological work on rabbits, cows and other animals. Attached is a list of publications. Reprints are being forwarded under separate cover. HOKKAIDO IMPERIAL UNIVERSITY, SAPPORO Departments of Agriculture and Science Prof. Agricultural Chemistry, Eigi Takahashi Assft Prof. Nulo Ito Investigations of nutrition of animals. No research was done during the war. Prof. Biochemistry, Yukihiko Nakamura Chemical and physical chemical studies of starches. Work published prior to 1940. Department of Science Prof. Organic Chemistry, Harusada Suginome Isolated "Kobusin" a new alkaloid from aconite. A summary of more recent study of the structure of aconite alkaloids is attached. HOKKAIDO IMPERIAL UNIVERSITY, SAPPORO Department of Agricultural Chemistry, Applied Mycology —Dr. Jun Hanzawa - Prof. Applied Mycology (Retired) Dr. Y. Sasaki - Prof. Applied Mycology Dr. Hanzawa, retired Prof, of Applied Mycology, after 39 years on the faculty, has worked mainly in the application of microorganisms to agricul- ture, industrial fermentations, and the preparation of fermented foods. (1) A fermented soybean food nNatto” widely used in Japan, is the result of his re- search. (2) The application of the flax retting principle (pectinase break- down by microorganisms) to mulberry bark (waste from silk industry) to cotton 47 M-AB RESTRICTED ENCLOSURE (A), continued plant stalk and to Manchurian Phiblscus in the preparation of a strong durable fiber for gunny sack (burlap) production, is an outgrowth of his research. (3) During the war, glucose has been derived from potato starch for use in the work in the laboratory. (4) As in most other laboratories work on the isola- tion of Penioillium metatum and the preparation of Penicillin has been and is in progress. Attempted isolation of other molds with antibiotic capacities is underway. The laboratory at the University is old and unkempt. As in most insti- tutions reagents are lacking and the knowledge of research being done in the States is meager. Requests for Information on Penicillin production are con- tinually sought. Dr. Y. Sasaki is now the Prof, of Applied Mycology carrying on the work reported above. He is a former student of Dr. Hanzawa. His present interest is in the classification of the mycoderms. HOKKAIDO IMPERIAL UNIVERSITY, SAPPORO Cryological Institute Prof. N. Nakamura, Medical Director Low temperature chambers capable of producing 25 °G and 40° C temperature are in use. Considerable emphasis was placed upon the studies begun in 1943 bo alle- viate frostbite. No practical applications were developed. Rapid freezing of meat and vegetables is being studied at present. Detailed abstracts and related reports will be submitted under separate cover, A list of research projects undertaken during the past two years is at- tached. XVIH. MINISTRY OF HEALTH AND SOCIAL AFFAIRS, TOKYO Bureau of Hygiene and Sanitation MINISTRY OF HEALTH AND SOCIAL AFFAIRS, TOKYO Bureau of Hygiene and Sanitation The following officials of the Bureau of Hygiene and Sanitation were in- terviewed: Dr. Maseyoshi Yamaguchi Division for Prevention Dr. Taizo Ashida of Chronic Diseases Dr, Yushlchi Minamizaki Chief of the Division for Prevention of Communicable Diseases Dr. Yokiharu Miki Chief of the Division of Health 48 RESTRICTED M- A B The Bureau of Hygiene and Sanitation according to these officials is an— administrative organization whose relationship to research is one of coopera- tion and application. Thus, for research, the Division for Prevention of Chronic Diseases depends largely on the Tuberculosis Research Institute under Dr. H. Oka (reported separately); the Division for Prevention of Communicable Diseases depends on the Government Institute for Infectious Diseases (reported separately) and the Division of Health is chiefly concerned with problems of nutrition which are investigated by the National Nutrition Institute. A list of projects which were under investigation in this Institute have been review- ed by the committee chemist, who has indicated no further action is necessary. XIX. NATIONAL RESEARCH COUNCIL OF JAPAN Projects Reports on Projects NATIONAL RESEARCH COUNCIL OF JAPAN Projects Director: Dr. Haruo Hayashi The Medical Section was Supervised by Dr. Y. Miyagawa Funds are granted by the Bureau of Education to the National Research Council which recives and passes upon applications for financial support from investigators. Average yearly grants amount to 18 million yen of which 10 million was devoted to war work. Approximately four million yen went to medi- cal and related research. Completed reports up to 1943 are published in journals of the council with the exception of those investigations carried out for the Army and Navy. Results of work for the Army and Navy were not made known to the council. A list of projects relating to medicine is attached. Investigation of \hese projects is under way. SUBJECTS RESEARCH AIM NAME OF CHIEF RESEARCHER Flight medicine ¥260,000 Study of high altitude fly- ing and diving for purpose of trying to increase abil- ity to withstand these and to prevent dangers. Kato, Toyojiro and 70 others. Tohoku Imp, U. Underwater medicine ¥100,000 Study to improve living con- ditions in submarine and to increase operating effic- iency. Hisano, Nei and 15 others, Nagoya Imp. U. 49 M-AB RESTRICTED ENCLOSURE (A), continued SUBJECTS RESEARCH AIM NAME OF CHIEF RESEARCHER Ability to stand heat and acclima- tization. ¥110,000 Study to promote working efficiency and to direct way of living by examining individual differences in ability to stand heat and suitability for life in tropics. Hlsano, Nei and 17 others. Acclimatization to low temperature. ¥120,000 Study on method of protect- ion against cold, precaut- ions against frostbite and further to find a method of increasing ability to stand cold. Toda, Masazo and 8 others, Kyoto Imp. U. Nutrition in the tropics and in cold regions. ¥45,000 Study on selection of food stuff suitable for climate and on method of increasing production and of storage. Toda, Masazo and 15 others. Kyoto Imp. U. Physical power ¥30,000 Study on maintenance and pro- motion of physical power of people and on individual’s suitability to various man- ual work. Umamoto, Masa- zaburo and 30 others. Gioftikai Med. Sch. Sight strengthen- ing, ¥54,000 Prevention of nearsightedness and strengthening of sight in daylight and night. Shioji Yoshiji and 15 others. Tokyo Imp. U. The health of in- fants . ¥50,000 Study on nutrition of infants in wartime, prevention of sickness, motherly care, me- thod of keeping health of work- ing women. Kuriyama, Shig- enobu and 24 others, Tokyo Imp. U. Blood transfusion substitute. ¥180,000 Study of blood transrusion substitute medicine, method of storing of blood, method of blood transfusion. Nakazumi, Masa- toku and 12 others. Tokyo Imp. U. Physical constitut- ions. ¥20,000 To study ability and change in ability to resist var- ious diseases from stand- point of constitution and type of body. Koiko, Kyuji and 23 others, Chiba Med. Col. Hot Springs ¥38,000 To study effect of natural hot springs and to apply this in recovery from fatigue. Misawa, Keigi and 11 others. Tokyo Imp. U. Hormone Vitamins ¥60,000 Study of mechanism of action and method of use of (vitamin hormone), Shimizu, Tayei and 17 others. Okayama Med, Col, 50 RESTRICTED M-AB ENCLOSURE (A), continued SUBJECTS RESEARCH AIM NAME OF CHIEF RESEARCHER Infectious cerebro- spinal meningitis ¥50,000 Various chemotherapeutic methods parallel use of in- noculation serum, measures against carriers, and improv- mont of vaccine. Miyakawa, Yoneji end 5 others. Tokyo Imp. U. Digitalis ¥27,000 Submitted on report from 22 Sept, thru 8 Oct. 45. Kobayashl and Ishidate Tokyo Imp. U, Prevention of malaria and treatment. ¥60,000 Prevention of malaria, malarial mosquitoes, san- itary installations, treat- ment test of efficacy of new medicines. Hayashi, Haruo Preparation of anti- malar ials ¥60,000 Synthesis of new anti-Mal- arial compounds. Asahina, Haruhlko Prevention of dengue fever and treatment ¥50,000 Culture of dengue parasite, animal innoculation method of diagnosis, experiment with human being. Koizumi, Tan Leprosy ¥50,000 Animal innoculation, cul- ture of bacteria, now chem- othera phy. Ota, Masao Breeding of small animals for experi- ments . ¥25,000 Finding best method for quickly increasing number of small animals for ex- periments. Okada, Kaname and 9 others. Tokyo Imp. U. Regulating mechanism in living body and its military application ¥40,000 Aim to create new type of equipment. Alda, Tokusuke and 8 others, Tokyo Imp. U. Emission Ray ¥120,000 Study on method of indirect X-ray photography, on its application to group exam- ination for tuberculosis and on effects of various emission rays on living matters. Nakazumi, Masa- toku and 12 others, Tokyo Imp. U. Tuberculosis ¥140,000 Study on innoculation against tuberculosis, im- provement in method of treatment, and on problem of work for tuberculosis patients. Imamura, Arao and 63 others. Osaka Imp. U. 51 M-AB RESTRICTED ENCLOSURE (A), continued SUBJECTS RESEARCH AIM NAME OF CHIEF RESEARCHER Filterable viruses ¥20,000 Study of influenza, small pox, traehoma. Takeuchi, Matsu- ,3 iro and 21 others. Osaka Imp. U. Immunity ¥50,000 Study on innooulations against various infectious diseases, mass production of innoculation serums, methods of storage and use. Tamiya, Takeo and 28 others, Tokyo Imp, U. Fatigue ¥94,000 Study of nature, diagnos- tic method, prevention of and recovery from fatigue. Katsunuma, Seize and 36 others. Nagoya Imp. U. Nutrition effic- iency ¥78,000 Study on nutritional value of wartime food in Japan, Korea, Manchuria, and deter- mination of minimum amount required for different pro- fessions . Toda, Masazo and 13 others. Kyoto Imp, U. Eruptive typhus ¥96,000 Study on innoculation against diagnosis extermination of er- uptive typhus and also on prob- lems concerning mass living sanitation. Miyakawa, Yoneji and 20 others. Tokyo Imp. U, Brain Waves ¥38,000 Study on picturization of brain wave and its application. Katsunuma, Seizo and 11 others. Tokyo Imp. U. Enzymes ¥40,000 Chemical research on various enzymes and quantity production of those which can be used to increase physical power and heat standing ability. Kobu, Yashiro and 16 others Osaka Imp. U. Physical Standards for Japanese ¥40,000 Determination of physical Standards by measuring young and old male Japanese. Nishi, Naruko and 24 others. Tokyo Imp. U. Insects. ¥35,000 To make clear the cycle of diseases such as mal- aria and eruptive typhus which are carried by in- sects and to study prevent- ion of these diseases. Bokuzawa, Sanji and 13 others, Tohoku Imp. U. Military horses and animals Study on increasing prod- uction of military horses and other animals for military use and on their sanitation so that source of military horses in wartime can be maintained. Emoto, Osamu and 14 others. Tokyo Imp, U. 52 RESTRICTED M-AB ENCLOSURE (A), continued NAME OF CHIEF SUBJECTS RESEARCH AIM RESEARCHER Domestic animals To plan to increase number Masui, Kiyoshi and domestic fowls of best domestic animals and and 11 others. ¥44,000 fowls by applying principles of heredity in present sit- uation of insufficient feed. Tokyo Imp. U. Parasites of To exterminate harmful para- Yoshimura, Ishiro domestics animals sites of domestic animals, to and $ others. promote efficiency of mili- tary horses and general domestic animals. Vet. College Wartime food for Treating of food stuff; Yabuta, Teijiro health. rationalization of combin- and 28 others. ¥89,000 ation and cooking; preparing food from things not used as food but which are edible, making inedible substances edible; grains powdered food; country food stuffs; search and use of natural vitamin Tokyo Imp. U. sources; effects of vitamin and others in a limited food supply. Electronic micro- To study to improve elect- Seto, Shozo scope, ronic microscope itself and and 8 others. ¥30,000 to give basic assistance in Tokyo Imp. U. solving various problems which require early solution. NATIONAL RESEARCH COUNCIL OF JAPAN Reports on Projects The following NRG projects have been turned over to other sections, as indicated, for investigation; since the subject indicated that the project would be of primary interest to that section. 1. Wartime Water Works and Sewage - To Office of Chief Engineer - Major Block. 2. Flight Medicine - To ATIG, FEAT - Capt. Castor. 3. Underwater Medicine - To NAVTECF-T4T> - Comdr. Ayres. The following projects have been reviewed by the committee and it is con- sidered that no further action is required. Many have been reported upjn un- der the institute where the work was done. 1, Studies on the regulatory function in the animal body. 2„ Factors influencing the growth and fermentation of microbes. 3. Nutrition Projects. 53 M-AB RESTRICTED ENCLOSURE (A), continued 4. X-Ray indirect radiography, 5. Electro-encephalograms. 6. Balneotheraph. 7. Studies on Vitamins, 8. Substitution Method for Blood Transfusion. 9. Studies on Epidemic Cerebrospinal Meningitis, 10. Studies on Epidemic Typhus, 11. The metabolism and the action of Vitamins under hot temperature. 12. Section for the preparation of Anti-Malarial Remedies. 13. Chemotherapy of Tuberculosis, 14. Malnutrition. Is. Electron-Miscroscope. 16. Studies on Architectural Hygiene and Equipment. 17. X-rays. 18. Projects relating to Physical Strength. Attached are reports from the Japanese on the above subject. XX. KANAZAWA GOVERNMENT MEDICAL COLLEGE Biochemistry Department Internal Medicine Bacteriological Institute Department of Pharmacy Department of Pharmacology KANAZAWA GOVERNMENT MEDICAL COLLEGE Biochemistry Department Prof. Ken Iwasaki Investigated and developed gasometric methods for chemical analysis. Has particularly studied and developed methods for determination of urea, uric acid, creatinine, gurnidine, etc. in blood. Has developed a gas measuring ap- paratus in which 10 micrograms of Nitrogen can be determined, forwarded under separate cover. He also studied methods for the determination of lodine, 54 RESTRICTED M-AB ENCLOSURE (A), continued The laboratory was very well equipped and organized and the reviewer be- lieves the qualify of work to be good. Attached are a list and reprints of the work of the department. KANAZAWA GOVERNMENT MEDICAL COLLEGE Internal Medicine Dr. M. Suzuki, Prof, of Internal Medicine Considerable work has been done by Dr. Suzuki .on chemotherapy in tuber- culosis. A study is now in progress on the treatment of tuberculosis with oaminophenal, Of 60 patients treated, 10$ showed a disappearance of the org- anism from sputa, urine, or gastric washings, and on x-ray examination, heal- ing of the lesions. This is a preliminary report. No ill effects were reported in any of the patients up to this time. Reprints of the work on tuberculosis will be forwarded under separate cover. Reference is made to report on the Pharmacology department of this col- lege . KANAZAWA GOVERNMENT MEDICAL COLLEGE Bacteriological Institute Dr, Tani, Director of Bacteriological Institute The main interest of the institute has been in spirochaetal studies. Ef- forts are being directed principally in all effort to culture T, pallidum in- vitro and to prepare a vaccine. Seventy four reprints of the work in this Institute have been obtained. A translated listing of this work from 1940 to 1945 is attached. These art- icles are published in the faculty organ. KANAZAWA GOVERNMENT MEDICAL COLLEGE Department of Pharmacy Prof. Yoshio Bakurai Investigated certain alkaloids and found one (Nupharidin) useful as a local anesthetic. Attached are two reprints and a list of publications with titles which were published in the Tokyo Journal of Japanese Pharmaceutical Society (re- prints were not available). 55 M-AB RESTRICTED ENCLOSURE (A), continued KANAZAWA GOVERNMENT MEDICAL COLLEGE Department of Pharmacology Director: Dr. N, Ishizaka Investigated and synthesized new compounds for chemotherapy of pneumonia. Developed a compound (Decasulphone) which is claimed to be more effective a- gainst streptococcus pneumonia. Reprints attached, samples (2) under separate cover. Tested numerous alkaloids and new synthetic compounds for treatment of bird malaria, Dirnethozy-8-diethylaminocthylamino-q.uinoline was found the most satisfactory (sample under separate cover). A list of compounds and sum- mary of tests conducted are attached. A list of papers from the department, with titles and reprints are at- tached. Dr. H. Okamoto, Prof, of Pharmacology A product o-aminophenol is being used after in-vitro and in- vivo (animal tests) - in human therapy in tuberculosis. The at- tached digest of this work is self expanatory. Samples of o-aminophenol and another product. Three-aminophen-oxazon - (2) have been procurred. Also an ampule of the o-amlnophenol in solution, as used in therapy, will be forwarded under separate cover. Reprints on the work on o-aminophenol and on Prof. Okamoto's work on streptolysin will be forwarded under separate cover. XXI. KYOTO IMPERIAL UNIVERSITY MEDICAL COLLEGE Leprosy Institute Microbiology Pharmaceutical Department Department of Pharmacology Research Projects Tropical Diseases Laboratorium for Chemical Research 56 RESTRICTED M-AB ENCLOSURE (A), continued KYOTO IMPERIAL UNIVERSITY MEDICAL COLLEGE Leprosy Institute Director; Dr. Noboru Ogasawara Studies were carried out on 10 patients in the institute, principally clinical work in relation to metabolism and leprosy. Some work is being done on the use of gold preparations. No direct microbiological work or work on transmission or amimal inoculation is being done. KYOTO IMPERIAL UNIVERSITY MEDICAL COLLEGE Microbiology Dr, Kimura, Microbiologist and Dean of School Dr, Kimura is the pioneer in electronic microscopy in Japan, using an in- strument which he constructed. His photographs of microorganisms are the equal of any done in the U.S.A. (Mudd). His most pertinent observations in this field are on the intracellular granular materiel of the paratyphoids - other gram negatives and on C, diphtherias. The exact nature and importance of the bodies brought to light by the electronic microscope has not yet been observed elsewhere and is in corroboration with American and German work. The other studies by Dr. Kimura include the following: Fowl pest - The development of a formolinized vaccine (virus) giving good immunity. Experimental inoculation of dogs with bovine and human T.B. - Dog is re- sis tanli^to“Tomeir The dog, as a possible car- rier, is indicated. Differentiation of human and bovine T.B. - By chick embryo inoculation. Embryo more susceptible to the bovine strains. Dengue fever - Cultivation of virus on chick embryo and in mouse brain, A mouse brain vaccine showing good protection in animals prepared. Endemic typhus - Attempted animal infection intranasally, in open wounds, and on the conjunctiva. Resultant infection by any of these routes succes- sfully done. Two unpublished manuscripts on endemic typhus were picked up by Lt. Col. Sanders, GWS, Further data on this work could not be obtained. Bangs disease (Undulant fever) - Serum of dairy workers (Kyoto) showed two of 116 men with agglutinin titer one to 100, Of 29 cows tested, 11 gave positive reactions (reactors). Analysis of toxin by peptic and other enzyme digestion. A study on the nature of toxin. (Chemical) Tmimmologioal Properties of Cultured Leishmanla donovanl. Four rabbits were inoculated with killed (by heat) leptomanas forma of L. donovani. In the serum of these rabbits were found agglutinating substances, precipitins, complement-fixing antibodies and anaphylactic antibodies. All of these various reactions were said to be strain specific could tell the dif- ference between two strains of L. donovani. 57 M-AB RESTRICTED ENCLOSURE (A), continued Skin Reactions for the Diagnosis of Kala-Azar Antigen prepared from cultivated leptomonas forms. Injected 0,1 cc in- tradermally. Tested 16 Japanese soldiers infected with L. donovani and ob- tained positive results in all. The height of the reaction was from 12 to 24 hours. Some positive reactions were as much as 55 mm in diameter. Four con- trols were negative. About 30 cases of leishmaniasis in Japanese soldiers in Kyoto Hospital and many more in Himeji Hospital, near Kobe. All soldiers were from North China. Chemotherapy of Kala-Azar with Five Antimony Preparations. He found that all five drugs would cure striped squirrels infected with L. donovani. In vitro and toxicity studies were conducted. These drugs were also injected into a normal animal and then an emulsion of livers infected with L,donovani was inoculated intraperitoneally. All drugs prevented the squirrels from acquiring leishmaniasis. All controls contracted the disease. Injection of L. Donovani into Rabbit Testicles. Dr. Kimura injected leishmania and leptomas forms into the testicles of rabbits. In some animals the leishmania could be found in the liver, spleen and bone marrow but could always be found in the testicle. Reprints of the above publications are attached. KYOTO IMPERIAL UNIVERSITY MEDICAL COLLEGE Pharmaceutical Department Torizo Takahashi Synthesized numerous sulfur-pyridine containing compounds, list of com- pounds, as well as reprints are attached. KYOTO IMPERIAL UNIVERSITY MEDICAL COLLEGE Department of Pharmacology Prof. Klkuo Ogin Ass't. Prof. H, Yamazokl Takeka Seki, Assistant Investigated many compounds (list attached) for treatment of bird malar- ia. All were found less effective than atabrine with the exception of two methyl-mercapto six chlor - 9 - (diethylamino pentylamino) pyridino 3’2* : 2;3 quinoline chlor hydrate which was better than atabrine. Method of preparation attached, sample under separate cover. Investigate an antimony compound (antimonyl hexonate) prepared by Prof. Nakai at the National Chemical Institute, Tskatsukl. Method of preparation attached and samples under separate cover. It was found very effective in treatment of 10 human cases of Kala-azar (reprints attached) and has also been recently found of decided value in 30 human cases of Schistosomiasis. The compound is relatively non-toxic, given in a course of 25 to 50 intravenous injections of 0,5 to 0.6 gm. Lethal dose for 10 gm. mouse is 40 gm. 58 RESTRICTED M-AB ENCLOSURE (A), con tinned Investigated certain antipyretics and one was synthesized with properties similar to morphine. Three reprints attached. Attached is a list of 63 publications with at- tached reprints. KYOTO IMPERIAL UNIVERSITY MEDICAL COLLEGE Research Projects Attached is the report of the research projects in medicine that have been pursued by the members of the staff since 1940. Reprints of the articles which appeared to be of most interest are being forwarded under separate cover. Specific reports on most pertinent projects are submitted under separate title. KYOTO IMPERIAL UNIVERSITY MEDICAL COLLEGE Tropical Diseases Dr. S. Yamaguchi, Prof, in Department of Science Dr, Yamaguchi was a Captain in the Japanese Navy. From August 1943 to December 1944, he was doing research work in the Macassar Navy Institute for Tropical Disease in Macassar, Celebes. Malaria Most of his work was done on experimental bird malaria. He worked on the theory that a lowered oxygen tension, in the circulating blood, might help de- stroy the malaria parasites. Ten birds infected with a species of malaria (probably Plasmedium praecox) were first injected with quinine, then put in a glass dessicator and the air evacuated. They were kept at this negative pres- sure for 30 minutes. The treatment of birds in this manner was found more ef- fective than by the simple administration of quinine. During the past five years, he has published many papers on the parasites of fish and other animals. Reprints are being sent under separate cover. KYOTO IMPERIAL UNIVERSITY MEDICAL COLLEGE Laboratorlum for Chemical Research Director; Prof, S, Uchijino Prof. Uchijino, until 1942, was Director of Medical Chemical Institute, Imperial University, Sendai, and came to Kyoto in 1942. Extensive investigations were carried out on digestive proteolytic en- zymes. Enzymes from the kidney and liver of whales were recently studied. Attached are 44 reprints covering work done at Sendai and Kyoto since 1940. 59 M-AB RESTRICTED ENCLOSURE (A), continued XXII- KYUSHU IMPERIAL UNIVERSITY Faculty of Medicine Bacteriology Department Hygiene Department Orthopedic Surgery Pharmacology Pathology Department Public Health Department Clinical Division KYUSHU IMPERIAL UNIVERSITY Faculty of Medicine Bacteriology Department Dr. Tadao Toda, Prof, of Bacteriology and Protozoology Dr. Toda and his assistants have carried on an extensive research program during the war. of publications of the Department are being forward- ed under separate cover. Among the problems studied are included the follow- ing; 1. BCG immunization - Dr. Toda claims to be the first to have used BCG Immunization in Japan. He is the author of a monograph on the vaccine. He is in complete agreement with all other investigators in claiming marked reduc- tion of tuberculosis morbidity and mortality among immunized individuals. His laboratory is the production center of BCG for use in Kyushu. 2. Leprosy - all attempts at cultivation of or animal infection with human leprosy bacilli failed. 3. Dengue - while the primary objective of Dr. Toda’s studies on dengue was to determine size of the virus, the interesting point is that he claims to have grown the virus on the chorioallantoic membrane of the developing chick embryo. A specimen of this virus in dried human blood, preserved in the frozen state since 1943, was infective to humans in 1945. A sample of the dried blood has been secured for forwarding under separate cover. 4. Chemotherapy of malaria - experimental antlmalarial compounds were received from Prof. Takahashi of the Kyoto Imperial University for study. Among the group of compounds studied, one was regarded as having merit: 7 chlor 6 methoxy - 4-(a diathlamino S—p«nty— amino)— ( pyrldlno —3— 2* =2 • 3 chinolin) chiorhydrat 60 RESTRICTED M-AB ENCLOSURE (A), continued 3. Penicillin - an experimental product was obtained which was the -apeu- tioally effective but produced reactions. No commercial production of ■ -,ni- cillin was undertaken. No investigations of influenza, typhus or encephalitis were undertaken during the war. KYUSHU IMPERIAL UNIVERSITY Faculty of Medicine Hygiene Department Dr, Kiomi Atsubo, Prof, of Hygiene (and Parasitology) Dr. Atsubo has interested himself in climatology but also has sponsored some research on the identification and distribution of helminths. Reprints of publications of the Department of Hygiene are being forwarded under separate cover. KYUSHU IMPERIAL UNIVERSITY Faculty of Medicine Orthopedic Surgery S. Jirinaka, Dean of the Medical School and Prof, of Orthopedic Surgery "Prosthetic Limb Studies" 1. This department was asked early in the war to make researches into the problem of limb prosthesis and much work has been done along this line. The whole problem has been reviewed and the mechanies of various types of art- ificial limbs have been improved. Several new upper limb attachments have been devised to assist the crippled farmer in his occupations. Three papers axe appended. 2. Many studies have been conducted on the handling of trauma* amputa- tions and joint injuries. Studies on the case of histamin and choline inject- ed locally to prevent anklyosis and also on the use of fascia lata to prevent joint ankylosis have been made. 3. Much work has been done on the prevention of infection in traumatic joints and in compound fractures. He has developed no new techniques on ajus- tive proceedure, 4. The professor has just started a study on the effect of the atomic bomb on bone growth in children. The bone tissue from autopsies is being studied. KYUSHU IMPERIAL UNIVERSITY Faculty of Medicine Pharmacology Dr7~Tokushi Fukuda, Prof, of Pharmacology Research was conducted in three phases: Ist Phase; Digitalis and digitalis-like substances. Extensive studies were made on Nerium Odorum, habitat; South Asia, a powdered extract was prepared and experiments conducted in frogs and 61 M-AB RESTRICTED ENCLOSURE (AJ, continued rabbits. Action is the same as digitalis and found less toxic. Reprint attached. 2nd Phase: Pharmacology and Physiology of heart and blood vessels. Study of no significance. Reprint attached, 3rd Phase: Toxicological study of Globe fish (Japanese). A toxic sub- stance known as "Tetradotoxin" was found in liver and ovary of fish and sometimes in the skin. Muscle of fish not poi- sonous . Reprint attached. KYUSHU IMPERIAL UNIVERSITY Faculty of Medicine Pathology Department Dr. Tamaki Imai, Ass’t. Prof, of Pathology (Substitute for Dr. Kosaku Ono, Prof, of Pathology and Dr. Yukizo Ono, Emeritus Prof, of Pathology) Dr. Imai, who will succeed Dr. Yokizo Ono as Professor of Pathology, dis- cussed the work of the Department as follows: 1. Dr. Ono has spent many years studying the lymphatic system. His studies have been concerned chiefly with anatomy and physiology, the blood supply of the spleen, the etiology of splenomegaly and the pathogenesis of tuberculous lymphadenitis. 2. Dr. Ono has studied the problem of jaundice for 20 years. He is re- sponsible for the unitarism theory of icterus which implies that jaundice does not occur in the absence of liver pathology. 3. The autopsies performed on atomic bomb patients (24 total) are being reported to Colonel Oughterson, of the Atom Bomb Commission. Reprints have been requested for forwarding under separate cover. KYUSHU IMPERIAL UNIVERSITY Faculty of Medicine Public Health Department Dr. Harvo Mizushima, Prof, of Public Health Dr. Mizushima, who holds a degree of Doctor of Public Health from Johns Hopkins University, has devoted most of his research to population problems in Japan, Korea, Manchuria, and Mongolia. He has reported on population increa- ses in cities and rural areas, and has developed life tables for Japanese, Koreans, and Manchurians. In addition Dr. Mizusima has sponsored research in industrial hygiene, Vitamin G content of foods, purification of water by the oligodynamic action of silver, construction of houses for maximum comfort, ef- fects of ultraviolet irradiation, effect of high temperature on the develop- ment of tuberculosis, effect of low pressure on the development of tuberculo- 62 RESTRICTED M-AB ENCLOSURE (A), continued sis, bacteria which utilize carbon monoxide and the influence of fluorine in water on mottling of teeth in Koreans. Reprints of publications are being forwarded under separate cover. KYUSHU IMPERIAL UNIVERSITY Faculty of Medicine Clinical Division I. Y. Nakashima, Prof, of Radiology and Director of the University Hospital This is an active department and the professor has an excellent staff in- cluding Dr, K. Inouye {now K. Ishikawa) an international authority on the bio- logical effects of irradiation. The most important work of this department has been done quite recently on the Nagasaki atomic bomb study. This work is nearly completed and is to be published in the very near future. The department has been and will continue to cooperate with the Atomic Bomb Commission. The department is completely German in training and viewpoint and much work has been done on the roentgen treatment of tuberculosis and gastric ul- cer. A study has also been conducted on the treatment of hypertension with negative ions. Reprints are appended, 11. S. Tamura, Prof, of Ophthalmology H. Ikui, Assft. Prof, of Ophthalmology 1. The deT' ant sees about 1000 cases of tuberculosis of the eye a year and has h work on the disease. Studies have been conducted on the diagnosi .*apy and on the histopathology of ocular tuberculosis. A specially raction of Old Tuberculin and x-ray are used in their treatment which they claim is efficacious, 2. They have also been studying the problem of myopia. They have been making a comparative study of the effect of treatment by the use of convex lens and atropine installation. In advanced, severe cases operative removal of the lens is employed, 3. They have made an extensive study of the clinical and histo-patholog- ical aspects of trachoma. 4. They have worked in conjunction with the department of surgery on the ophthalmologlcal aspects and complications of neurosurgery. Reprints are appended, 111. Dr. T. Mltsuya, Prof, of Urology A large part of the work of this department, together with the apparatus used, was lost in the bombing and burning of the urological laboratory. 63 M-AB RESTRICTED ENCLOSURE I A), continued They have made a study of the normal physiology of the urinary tract using x-ray cinematographic methods. Peristaltic movements of the kidney, pelvis, ureters and bladder were studied. Reprints were requested for forwarding under separate cover, IV. Dr. F, Ishiyama, Prof, of Surgery The professor has the reputation of being one of the best surgeons in Japan. He is carrying on the work of his deceased predecessor, Prof. H. Miyakl, on gall stones. He has collected stones from Japanese living in China, Formosa, Korea and other parts of the world in an attempt to explain the high Incidence of bilirubin stones in Japanese. The professor has studied the composition of gall stones, using micro- copic, clinical, spectrographic and x-ray disfraction methods. He feels that the figures given in text books and in the literature for the incidence of various types of gall stones will have to be revised in the light of his re- searches. He feels that all the various analytical methods must be employed to determine the true make up of the calculus. He is now applying his methods to the analysis of urinary stones. His paper on X-ray crystalography is appended. 2. His department has used the Fuoh*3, Kurten and Sakai methods of diag- nosis in early gastric carcinomas. In their hands the tests are about 82% ac- curate and are falsely positive in about 15%. 3. Ishiyama has done over 500 gastric resections for cancer and does not hesitate to take the hepatic artery if he feels it is necessary. He has done this in about 10 cases and has been successful in all. They have shown by animal experimentation, that the liver blood supply is readily taken over by the gastrohepatico-duodenal artery. 4. He has done 40 frontal lobectomies in epileptics with discouraging results. He has resected the bronchial ganglia in 60 cases of asthma with mediocre results. His paper on post-operative pulmonary complications is appended. V. Dr, Shigeru Umayahara, Prof, of Obstertrlcs and Gynecology The Department of Obstetrics and Gynecology has Investigated such prob- lems as blood supply of the embryo, liver function in toxemia of pregnancy, action of various hormones, roentgen pelvimetry, physical measurements of the newborn, insufflation tests for tubal patency, Vitamin 0 excretion and sodium taurocholate as a treatment for sepsis. Reprints of publications are being forwarded under separate cover. VI. Dr. G. Kusunaki, Prof, of Internal Medicine The department of medicine of this university has an excellent reputation in Japan and is active in experimental and clinical research. 1. Studies have been conducted on the autonomic nervous system using the plcrotoxlc and section method. 64 RESTRICTED M-AB ENCLOSURE (A). continued By this method a small area in the ventral part of the pons has been shown to be the center for tonic control of the intestine and the spinal cord and peripheral paths have been worked out. Reprints are attached. 2. Studies have been and substance are now being conducted on the effect of gastric and duodenal and human saliva and serum on polycythemia and per- niceous anemia in the white rat. These studies have not been completed and have not been published. 3. They have shown that the use of gastric and duodenal substance in conjunction with typhoid vaccine causes a marked increase in the production of immune bodies and a higher titer is obtained than results from the use of the vaccine alone. A reprint of their paper on this reaction is appended. 4. The staff has conducted much experimental and clinical research on the problem of bronchial asthma. Many reprints on this problem are attached. They have used fever therapy and insulin shock therapy with claimed ex- cellent results. VII. Dr. M. Sasaki, Prof, of E-N-T. The professor has published numerous papers on his method of tonsilecto- my, on the clinical problem of tonsilitis, and on the removal of foreign bod- ies in the bronchial tree. Reprints are appended. VIII. T. Takeda, Prof, of Roentgenology The only study conducted in this department recently has been one on the use of X-Ray therapy in the treatment of leprosy. Good results have been claimed for the maculous form of the disease. The results in the nodular form of the disease. The results in the nodular form of the disease are not good. Reprints will be forwarded under separate cover. XXIII . NAGOYA IMPERIAL UNIVERSITY Faculty of Medicine Anatomy Department Bacteriology Department Hygiene Department Pharmacology Department Pathology and Parasitology Department of Pediatrics 65 M-AB RESTRICTED ENCLOSURE (A), continued Supplement to Section IX Clinical Division Comments on Medical Education NAGOYA IMPERIAL UNIVERSITY Faculty of Medicine Anatomy Department C. Togari, Prof, of Histology and Embryology The department has made many investigations in the histology and histo- genesis of various organs in rodents. Similar studies have been conducted on the sweat glands of the human ax- illa and on the nasal muscous membrane of man. Reprints will be submitted under separate cover. Dr. K. Yamado, Prof, of Anatomy (Micro) The professor has been interested in the variations and anatomical abnor- malities of trunk muscles of man, particularly of the levator scapulae. He has made exhaustive studies. Reprints will be submitted under separate cover. Dr. H. Nagamatsu, Prof, of Anatomy (gross) The professor is conducting, in conjunction with all Japanese anatomists, a comprehensive study of the Japanese body types. This work has not been published. NAGOYA IMPERIAL UNIVERSITY Faculty of Medicine Bacteriology Department Dr. Kazuo Ogasawara, Ass’t. Prof, of Bacteriology (Substitute for Dr. Mitsuzo Tsuruml, Prof, of Bacteriology) During the war the Department of Bacteriology concerned itself with stud- ies of the influenza virus. English, American and Japanese strains available for study were all type A. The few sporadic outbreaks of influenza in Japan during the war were identified by neutralization tests with patients sera as also due to type A virus. Experimentally, four types of influenza vaccine were prepared: 1. Emulsion of infected mouse lung tissue. 2. Tissue culture. 3. "Purified” suspensions of virus from mouse lung tissue. 4. Chick embryo preparations. 66 RESTRICTED M-AB ENCLOSURE (A), continued The first of these caused severe reactions in humans; the second was less drastic in its effect; the third was most acceptable to recipients. None was produced on a large scale and none was properly evaluated because there were no extensive outbreaks of the disease. In addition to the above, studies were made of the feasibility of using the Manchurian hamster (Gitellus mongolicus) as an experimental animal for Japanese encephalitis virus. It was found that the virus survived only three to four intracranial passages. According to Dr, Ogasawara, no Japanese encephalitis virus vaccine was produced in Japan for control purposes. The entire bacteriological laboratory and all equipment, data and cul- tures were destroyed during the first bombing attack on Nagoya. NAGOYA IMPERIAL UNIVERSITY Faculty of Medicine Hygiene Department Dr. Bogo Koinuma, Prof, of Hygiene During the war Dr. Koinuma studied the problem of industrial dusts. He tested a variety of face masks and decided that a mask consisting of fine lay- ers of "habutai” grade silk was most feasible for production in Japan. This mask, however, did not come into commercial production. In addition to silicosis occurring in coal and copper miners, foundry workers and sand blasters, Dr. Koinuma also listed dermatitis, carbon monoxide poisoning and pneumoconiosis in people grinding duraluminum as common indus- trial health problems. In addition, tuberculosis was reportedly common in the last named group. According to Dr. Koinuma, the protective creams used as preventives a- gainst dermatitis were of the cosmetic type and non specific in their effect. In addition, Japanese laborers were reluctant to wear proper respirators as a protection against dusts. Ventilation equipment to remove both dusts and other atmospheric contaminants were limited in use because of a lack of mater- ial , NAGOYA IMPERIAL UNIVERSITY Faculty of Medicine Pharmacology Department Dr, Makoto Miwa, Prof. Pharmacology Research carried on over period 1940 to 1945« 1, Action of Adrenalin on the secretion of the stomach. Conclusion: Adrenalin does not directly increase secretion of the stomach, but stimulates activity of the stomach, which in turn stimulates secretions, 2. Effects of oxygen and air on movement of intestines. 67 M-AB RESTRICTED ENCLOSURE (A), continued Conclusion: When oxygen content is reduced to nine percent, a marked decrease is noted in movement of intestines, from 20% to nine percent reduction. No change is noted. 3. Effect of acid on secretion of suprarenal glands. Conclusion; Injection of five cc. one percent Hel. showed an in- crease in secretion. 4. Action of caffeine as a heart stimulant. Conclusion: Caffeine stimulates heart by direct stimulation and not by increasing circulation of blood. This was proven by keeping blood pressure and rate of circulation constant. Blood pressure was held constant by withdrawing blood as circulation increased. Circulation of blood was held constant by withdrawing blood as blood pressure increas- ed. NAGOYA IMPERIAL UNIVERSITY Faculty of Medicine Pathology and Parasitology Dr, Fukuzo Oshima, Prof, of Pathology and Parasitology Dr. Oshima has devoted many years to the study of the distribution, path- ology and epediraiology of clonorchis sinensis, metagonimus yokagawai and Di- bothriocephalus latum infections. All three parasites are endemic in the pre- fectures surrounding Nagoya due to the native custom of eating raw or partial- ly cooked fish. Since there are no satisfactory therapeutic measures, the only practical procedure at present is to educate the people to cook fish be- fore eating. A reprint outlining some of this work is attached. During the war Dr, Oshima also studied the pathology in soldiers who died of malaria. Reprints of this work are attached. Before the war Dr. Oshima was studying carcinomas but was forced to dis- continue the work due to lack of supplies. At present he is interested in the etiology and transmission of chicken sarcoma. NAGOYA DOERIAL UNIVERSITY Faculty of Medicine Department of Pediatrics Dr. Kyoichi Nakae, Ass't. Prof, of Pediatrics (Substitute for Dr, Okira Sakamoto, Prof, of Pediatrics) ’TSKIRI” During the war the Department of Pediatrics was largely concerned with the study of "ekiri" (diarrhea in young children). The studies conducted by the staff show that the disease is prevalent in children between the ages of two and seven. Untreated patients have a 44% mortality rate. Death appears to be due to cardiovascular collapse. Experimented, observations seemed to show that intravenous saline and glucose combined with the administration of strophanthin was the therapeutic procedure of choice. RESTRICTED M-AB ENCLOSURE (A), continued The disease apparently is due to a variety of bacterial etiologic agents. A reprint is attached which describes the experimental observations made in- cluding etiology and therapy. NAGOYA IMPERIAL UNIVERSITY Faculty of Medicine Supplement to Section IX Dr. M. Nakashlma, Prof Ophthamology Dr. R. Hagino, Ass't, Prof. Ophthamology Work was accomplished on the use of Posterior Lobe of Anterior Pituitary Gland, where a Melanophalen Hormone was extracted and used in night blindness. This hormone was extracted from fish and prepared by Aoyama Institute, Tokyo (Commercial Pharmaceutical house). Dose: One cc, became effective after two hours and duration was about 24 iiours, Results: Night vision was improved, especially objects on the horizon. Fish glands were used only because of the supply. NAGOYA IMPERIAL UNIVERSITY Faculty of Medicine Clinical Division I. Dr, U. Kikukawa, Prof, of Obstetrics and Gynooology This is a busy clinical department and they have been conducting several clinical and experimental studies in the last five years: 1. A study of tuberculosis in pregnancy. 2. A clinical investigation of malignant chorionepitheloraa. 3. An extensive study of foetal bone ossification. 4. A study of placenta praevia, particularly its X-ray diagnosis. $. The use of laparoscopy in AZ tests. 6. A study of so-called foetal respirations by roentgenograpnic methods. Reprints will be forwarded under separate cover. 11. Dr. M. Akune, Prof., Oto-rhino-lar The experinemtal investigations of this department have been concerned with the physiological effects of industrial noises and of total body vibra- tions of high frequency: 1, The effect of noise on the Bj_ content of the livers of rabbits. 2! Histological changes in the organ of Corti of white mice subjected to factory (airplane riveting) noises. 3. A study of the effect of industrial noises on factory workers. 4. The effect of high frequency total body vibrations on the utrical sac of animals. Reprints will be forwarded under separate cover. 69 M-AB RESTRICTED ENCLOSURE (A), continued 111. A. Katsunuma, Prof, of Internal Medicine and Director of the Hospital. The professor is the leading figure at the school and hospital and is in- terested in hematology. 1. He devised the sterual puncture apparatus used by the Army and Navy. 2. He has made a study of the histology of marrow tissue in lead poison- ing. 3. He has devised a method of extracting cattle bones and uses the ex- tract in the treatment of emaciation due to starvation. 4. He has written a vdry interesting statistical paper on the incidence of the various types of brain tumor in Japan, showing the relative infrequence of gliomas and the high Incidence of parasitic cysts and tuberculosis. 5. Recently he has been working on the problem of fatigue in factory workers and has developed several fatigue tests. Reprints will be submitted under separate cover. S. Okada, Prof, of Internal Medicine The professor has made extracts of various carcinomatous lesions and uses them in the treatment of cancer. He also has an extract from inflamed gall bladders which he uses in the treatment of gall bladder disease. Reprints will be forwarded under separate cover. Oral Insulin Dr. Okada has prepared insulin for oral administration as follows: Eosin 0.01 gm. Acid pigment Methyl Violet 0.01 gm. Alkaline pigment Saporim 0.1 gm. Insulin - as required Insulin given in this manner requires three times the quantity of insulin as when administered hypedermlcally. Acid pigment prevents action of Pepsin Alkaline pigment prevents action of Trypsin Insulin prepared this way is absorbed by intestines Clinical study was made on 50 cases. IV. Dr. W. Saito, Prof, of Surgery The professor is one of the best known surgeons in Japan and has been very busy during the war with his practice and running the surgical wards at the hospital. He has done clinical research in spinal anesthesia and has directed a study of the oesophagus by roentgen kymography and tomagraphy. Reprints will be submitted under separate cover. 70 RESTRICTED M-AB ENCLOSURE (A), continued S, Kirihara, Prof, of Surgery The professor is head of the Second Surgical Service at the university hospital. He has done considerable experimental work in nerve suture and on surgical shock. He has also done considerable gastroscopy and has devised an improvement of the Wolf shindler flexible scope. Reprints forwarded under separate cover. V. U, Sugita,. Prof. of Psychiatry Has made an extensive study of the character and personalities of war factory workers and find that 20% of them are abnormal. He belives that poor leadership of factory foremen is responsible for most of the variations. He has also done considerable work with the use of the electroencephalo- gram in various psychosis. Attached are reprints on recent work. Other reprints will be forwarded under separate cover. VI. S, Uagura, Prof, of Orthopaedic Surgery The professor is world known for his studies of congenital dislocation of the hip and has seen over 1500 cases in his clinic in the last 20 years. He has continued his studies during the war. Reprints will be forwarded under separate cover. NAGOYA IMPERIAL UNIVERSITY Faculty of Medicine Comments on Medical Education Dr. H. Tamura, Prof. Dermatology and Dean of the Medical School The doctor’s work has been confined to administration of the medical fac- ulty and school. The medical college graduated the same number of doctors during the war as before (400 per class) but the curriculum was shortened from four to three years. There are (according to Dr. Tamura) 70,000 doctors in Japan and only about 20,000 of them are graduates of the full four year or four and one half year courses. He does not feel these men are properly trained and hopes many of them will return for graduate instruction. Like other Japanese doctors with whom this matter has been discussed, Tamura's main concern is that the profession is over-crowded. 71 M-AB RESTRICTED ENCLOSURE (A), continued XXIV. OKAYAMA UNIVERSITY Faculty of Medicine Anatomy Department Bacteriology Department Hygiene Department Clinical Division Pharmacology Department Pathology Department Physiology Department Department of Biochemistry OKAYAMA UNIVERSITY Faculty of Medicine Anatomy Department Dr. Masajl Seki, Prof, of Anatomy and President of the Japanese Anatomi- cal Society Dr. Seki and his staff have concerned themselves primarily with the hist- ological changes due to hot springs therapy. Available reprints detailing these and other studies are being forwarded under separate cover. All buildings and practically all equipment and publications of the De- partment of Anatomy were destroyed during an air raid. OKAYAMA UNIVERSITY Faculty of Medicine Bacteriology Department Dr.Sakae Murakami, Ass't, Prof, of Bacteriology (Substitute for Dr. M. Suzuki, Prof, of Bacteriology) s The Department of Bacteriology, which also teaches parasitology, has in- vestigated four major problems during the war. Available reprints are being forwarded: 1. Typhus vaccine - attempts were made to produce typhus vaccine from the peritoneal membranes of experimentally infected animals. This project never reached a practical conclusion. 2. Distribution of fluke infestation in fish - extensive surveys of the extent of metagonimus, clonorchis and other fluke infestations of fish have been made, using a digestion technic to liberate the encysted stages for iden- tification. 3. Salmonella types in Japan. 72 RESTRICTED M-AB ENCLOSURE (A), continued 4. Experimental therapy of R. prowazeki Infections in guinea pigs - a- mong a series of "chinon" derivatives prepared by the~Hayashi Pharmaceutical Company in Okayama, three have shown promise in the treatment of guinea pigs experimentally infected with Rickettsia prowazeki: Xyiochinon 2-6 Dimethoxychinon 2 Acetamlnochinoo OKAYAMA UNIVERSITY Faculty of Medicine Hygiene Department Dr, Masuo Ogata, Prof, of Hygiene Practically all research sponsored by Dr, Ogata has been concerned with fundamental immunological phenomena. A large number of reprints are being forwarded under separate cover. OKAYAMA UNIVERSITY Faculty of Medicine Clinical Division S. Inada, Prof, of Medicine I. K. Kitayama, Prof, of Internal Medicine 1. Professor Kitayama has directed a study in the clinical and immunolo- gical aspects of influenza. They have been unsuccesful in their attempt to develop a good immunization. 2. The department has done a great deal of work on the problem of ence- phalitis Japonium. They have used a mouse brain antigen but production was curtailed due to the war. 3. The professor (Kitayama) claims to have clarified the relationship between the mid brain and the hypophesis coribri. He has made, extensive stu- dies of the blood vessel and nerve fibres anatomy in the region of the tuber- cenerium. He claims to have demonstrated a much closer neurovascular rela- tionship between the pituitary gland and the mesencephelon than other workers. 11. Dr. Hideo Yagl, Director of Gynecologic and Obstetric Clinic Dr. Yagi has sponsored research programs dealing with problems of female sterility, treatment of carcinoma of the cervix and prevention of prenatal and neonatal deaths. Reprints of staff publications are being forwarded under separate cover. While studying the diagnosis of the causes of sterility, Doctor Yagi developed a modification of the Rubin test for tubal patency. His method con- sists of installing sterile saline into one tube at a time, through a special- ly designed instrument which blocks off the tube not being tested. The volume and rate of flow through each tube are charted and the graphs obtained furnish comparative data on the patency of the tubes. Diagrams of the apparatus and sample charts are given in one of the above mentioned reprints. 73 M-AB RESTRICTED ENCLOSURE (A), continued Dr. Yagi also maintains an excellent pathology museum for teaching pur- poses. , v. 111. E. Eamamato, Prof. of Paediatrics. The professor’s staff was greatly curtailed during the war and he has been busy with clinical work. Recently he has become interested in the study of certain sulphur pro- teins in milk and serum. Reprints have bean requested and will be forwarded under separate cover. IV. B, Hata, Prof, of Opthalmology M. Kajiura, Ass’t, Prof, of Opthalmology This department has been conducting investigations into the problem of myopia. They are conducting clinical and animal experiments to show the ef- fect of general diseases on the development of near sightedness. Reprints will be forwarded under separate cover. V. M. Hayashi, Prof, of Psychiatry The department of psychiatry has been conducting a clinical investigation of schizophrenia. They have shown the C02 tension of cerebral blood to be low in aggravated dementia praocox and rises on amelioration of the patient’s condition. They have also shown the temperature of the brain to be subnormal in schizophrenics. Reprints will be forwarded under separate cover. VI. H, Negishi, Prof, of Urology and Dermatology The professor’s clinical researches have been on the therapy of syphilis. He has also conducted many animal experiments on bismuth absorption and elim- ination and on the spinal fluid concentration of the metal. He has been at- tempting to find a method of improving the spinal fluid absorption. He has also done some experiments with auto transplanted dog kidneys and on the effect of Vitamin C deficiency on the suseptibility of the rabbit skin to infections. Reprints will be forwarded under separate cover. VII. S. Tsuda, Prof, of Surgery The professor has been working chiefly on various serum and urine tests for cancer. He has confirmed the work of Fuchs and other German and Japanese workers in this field. He has also revised interest in the use of a colibacillus antivirus in the treatment of peritonitis. The professor has always been interested in the problem of pancreatitis and he has continued his studies on the condition. Reprints will be forwarded under separate cover. 74 RESTRICTED M-AB ENCLOSURE (A), continued OKAYAMA UNIVERSITY Faculty of Medicine Pharmacology Department Df, Kanichiro Okushima, Prof, of Pharmacology Research for past five years was conducted in tv/o phases. First Phase constituted functional and morphological studies of various organs, and the action of drugs, especially on the central nervous system. Second Phase constituted experimental and chemotherapeutic studies upon various infectious diseases, particularly Typhoid Dysentery, by the Aromatic Guanidin derivatives, especially P. oxybenzyl-guanidin. Reprints attached. OKAYAMA UNIVERSITY Faculty of Medicine Pathology Department Dr. Hlroshi~Tanabe, Prof, of Pathology Dr. Tanabe has been interested in the following problems and has fur- nished available reprints to be forwarded under separate cover: 1. Effects of the atomic bomb explosion in Hiroshima - Dr. Tanabe autop- sied 19 patients in Hiroshima and 10 in Okayama. Reports are being sent to the Atomic Bomb Commission. 2. Pathology of Japanese virus encephalitis. 3. Pathological changes in endocrine glands associated with hydrogen sulfide or carbon disulfide poisoning. 4. Physiology and pathology of endocrine glands. 5. Pathology of interstitial pneumonia. 6. Pathology of pukmonary tuberculosis. Dr. Y, Hamazaki, Ass't. Prof, of Pathology Dr. Hamazaki has published an extensive series of histopathologic studies dealing with virus inclusion bodies and various intracellular structures dem- onstrated by special stains. Reprints are being forwarded under separate cover. OKAYAMA UNIVERSITY Faculty of Medicine Physiology Department Dr. Kanae Hayashi, Prof, of Physiology Prof. Hayashi concentrated his studies on the effects of various condi- tions on blood vessel walls, for the protection and cure of Arteriosclerosis. 75 M-AB RESTRICTED ENCLOSURE (A), continued He claims that Vitamin C, upon Epinephrine-Arteriosclerosis protects tho blood vessel walls and cures arteriosclerosis. Reprints attached. OKAYAMA UNIVERSITY Faculty of Medicine Department of Biochemistry Dr. Shimizu Tael, Prof, of Biochemistry Dr. Kazuno Taro, Ass’t. Prof, of Biochemistry Study on the physiology and chemistry of bile and, especially the origin and the formation of bile acid with 24 carbon atoms. The gall-bladder of different kinds of animals.(fish, the water lizard, the snapping turtle, birds, otter and buffalo) were studied and separated var- ious kinds of sterols {C2S C 27 or sterochalic Acids (Cp6 C 27 which have a constitution 6f cn6lic acid or cholic acid itself** Furthermore, it was established that the other bile acids are formed from the cholic acid under oxyd-reduction in the animal body. Studies made on relation between the cancerous disease and the abnormal production of nucleic bases. (1) Nucleic base Uracil stimulates the growth of cancer tumor of the rat. (2) Nucleic base Uracil decreases Carbohydrate Metabolism of the rabbit. (3) The cancer tissue shows a remarkable decrease of Vitamin Bi. (4) The Uracil content is found abundantly in young rabbits and it is increased in cases of rats with growing implanted cancer tumor or in case of Vitamin A deficiency. Reprints attached. XXV. OSAKA IMPERIAL UNIVERSITY Faculty of Medicine Department of Biochemistry Microbiological Institute Department of Pharmacology Physiology Laboratory Surgical Clinic Takeo Institute for Microbial Disease Internal Medicine 76 RESTRICTED M-AB ENCLOSURE (A), continued OSAKA IMHSRIAL UNIVERSITY Faculty of Medicine Department of Biochemistry Prof. K. Ichlhara Investigated enzymatic reactions, particularly the production of indol from Tryptophane by bacteria. Studied the enzymatic oxidation of ascorbic acid. An outline of the work as well as reprints are attached. OSAKA IMPERIAL UNIVERSITY Faculty of Medicine Microbiological Institute Dr. Tenjl Taniguchi, Director, Microbiological Institute Directly interested in virus and virus-like diseases from the standpoint of the elementary bodies and inclusion bodies. Principally the relationship to pathogenicity, etiology and the life cycle. A listing of research for the past five years is appended. Reprints on the completed phases of this work will be forwarded under separate cover. This institute has been engaged in the production of vaccines, antisera and antitoxins. None are different from those produced in other government laboratories. Buildings and laboratory facilities exhibit the unkemptness observed elsewhere. The director, Dr. Taniguchi, from his works, is an internationally recog- nized individual in the field of microbiology. A listing of his research pub- lications to 1941 is included in the reprints. Has done work on exo evythrocytic malaria in chickens (gallinaoeum). OSAKA IMPERIAL UNIVERSITY Faculty of* Medicine Department of Pharmacology Prof. M. Okagawa Assistants: I. Yamamoto; E. Nichikawa; J. Ando; F. Ito Professor Okagawa and his four assistants were interviewed. His most im- portant investigations were studies on the pharmacology of adrenalin. He has studied the effect of vitamin C on adrenalin content of suprarenal gland and has published a paper on the formation of adrenalin from dioxyphenylalanine (the mother substance). He studied over 100 drugs and essential oils as repellents for mosquitos. Those of value were capronic acid, caprilic acid, Shiso oil (from the shiso plant, grown in Hokkaido, containing 35% Pelliraldehyde) benzaldehyde, benzop- henene, citronellaldehyde, and citronellyl acetate. The last three were the best. This work is not yet published. Attached is a list of more recent studies, as well as reprints of their studies. 77 M-AB RESTRICTED ENCLOSURE (A), continued OSAKA IMPERIAL UNIVERSITY Faculty of Medicine Physiology Laboratory Prof.H. Kubo Investigation of oxidation-reduction potentials of various Biologic and Chemical systems. Attached is a list of papers published and three reprints. OSAKA IMPERIAL UNIVERSITY Faculty of Medicine Surgical Clinic Director: N, Takebayashi Investigated the detoxification of Sulfanilimides in the animal body. Evidence submitted that nicotine acid may assist in the acetylation of Sulfan- ilimides. Three reprints attached. Hideo Sei; Investigated the physiology of the spleen and has prepared a spleen pre- paration which caused an increase in red blood corpuscles. This preparation is in the experimental stage, but is prepared as follows: Crushed fresh cows spleens are washed with acetone and ether and stored in sealed containers. Ten such spleen treated with BKg acetone, containing a trace of and then 1.8 Kg ether. The dried material is extracted five times with two percent Na Cl at 38* C for one hour, centrifuged and filtered. An equal amount of glucose is added and the solution is refrigerated 24 hours, crystals separate which are claimed when given in one gram doses to cause the rapid production of red blood cor- puscles, A second method for production of active material is to add 10 cc of water plus 10 cc of Alcohol, containing O.5jS H Cl to one gram of dried spleen material. Crystal like material forms on the surface. Attached is an outline of this work. H. Iwanaga, Chief Surgeon M. Hama, Assistant Investigated a blood clotting material prepared by treating cows blood with one percent hydrogen peroxide. The foam is skimmed off dried, dissolved in salt solution and prepared for injection. Ampoules forwarded under separ- ate cover. One or two ampoules of a two percent solution are said to stop bleeding from serious wounds. Investigated and prepared a hemicellulose (Sulfuric Acid ester) which was found useful as a substitute for blood plasma. Sample under separate cover. Developed Histaminase and found it very useful in treating allergic con- ditions. Sample under separate cover. 78 RESTRICTED M-AB ENCLOSURE (A), con*'.nued OSAKA IMPERIAL UNIVERSITY Faculty of Medicine Tekeo Institute Microbial Disease Dr, Arao Imamura, Director, Third Clinic for Internal Medicine, Osaka University; Director, Takeo Institute for Tuberculosis, Osaka University. Dr. Imamura is primarily working in tuberculosis, as director of the in- stitute. He has been instrumental in the initiation of the B.C.G. vaccination program in Japan. From his statistics, over al5 year period, a definite re- duction in the incidence of tuberculosis among the vaccinated is shown. By means of a mobile laboratory, over 700 thousand individual examinations of civilians from infancy to old age have been made, in determining further the prevalence of tuberculosis. The work in progress at present is principally directed toward developing new attenuated M. tuberculosis Hominis strains by cultivation on a glycerine- gall-potato medium. Four strains showing a high degree of attenuation by ani- mal experimentation, have been developed. These have not been used in humans. A so-called spectroscopic diagnostic method for cancer, using an extract of cancerous tissue and serum, has been developed. Reprints of research will be forwarded under separate cover. A digest of the cancer diagnostic method is appended. OSAKA IMPERIAL UNIVERSITY Faculty of Medicine Internal Medicine Dr. Arao Imamura, Prof. Internal Medicine A specific Acid Turbidity Reaction Test for cancer diagnosis has been de- veloped. The method, in Japanese hands, shows promise. The procedure is at- tached. Also, attached are reprints of 111 Clinic for Internal Medicine. XXVI. TOKYO JIKEIKAI MEDICAL UNIVERSITY Department of Forensic Medicine TOKYO JIKEIKAI MEDICAL UNIVERSITY Department of Forensic Medicine Prof. Mitsuteru Ishlkawa Professor Ishikawa investigated Anaphylaxis in animals since 1934, with the object of its application to the prevention and treatment of allergic dis- eases. though no clinical application has been made to date. Little attention to date has been made by the clinicians to allergic diseases and their treat- ment . 79 M-AB RESTRICTED ENCLOSURE (A), continued Recent work has been on sensitization of animals to drugs and chemicals, somewhat similar to that of Landsteiner*s work. He has attempted to differen- tiate between chemicals causing skin sensitivity alone, or those causing skin and intestinal muscle sensitivity in guinea pigs. For example, aspirin and barbital, quinine, chromium compounds, cresols caused only skin reactions while iodine, such as lugols solution produced both skin and muscle sensitiv- ity. He was unable to sensitize animals to thyroxin. Attached is an outline of the research activities of Jikelkai Medical University, also the collected research papers of Prof. Ishlkawa on Anaphyl- axis. XXVII. AGRICULTURAL EXPERIMENTAL STATION Director of Research AGRICULTURAL EXPERIMENTAL INSTITUTE Director of Research Dr. Teijiro Yabuta, Chemical Engineer, Director of Research Investigations of interest were the studies made on Vitamin Bq and C: Vitamin Bq was obtained from peanut skins and Dr, Yabuta states that it contains about 7000 units of Vitamin Bq in 100 Gme. as compared to rice embrlo which contains 4500 units of Vitamin Bq in 100 Gms. Vitamin C was found present in Persimmon Leaves and in Walnut Leaves from one percent to two percent on the basis of dried leaves. Reprints attached. XXVIII. YOGA MEDICAL SUPPLY DEPOT, TOKYO Research Department YOGA MEDICAL SUPPLY DEPOT, TOKYO Research Department Lt. Col, T, Yamanouchi, Director of Research Research Plan since 1940 constituted studies on Cardiotanics, disinfect- ants, anesthetics, sulphanamides, Vitamins, anti-malaria remedies, and inves- tigations for substitutes of chemicals and provision against lowering of spec- ifecatlons. 80 RESTRICTED M-AB ENCLOSURE (A), continued Investigations of interest are as follows; 1. Caffeine sodium acetate and sodium naphtaline-sulphate were produced experimentally to economize the usage of toluene, the raw material for caffe- ine sodium benzoate. 2. Synthesis of dimethyl ester of phthalic acid. 3. Simplified method of obtaining local anesthetic by the combination of p-aminobenzoin ethyl ester and p-phenol-sulphonic acid. 4. Synthesis of sulphabenzotriazole for a new chemotherapeutic medicine, 5. Synthesis of thiazole nucleus for vitamin without the use of phos- phorus compounds. 6. Utilization of butyl ester of gallic acid to prevent oxidation of vitamin A. 7. Promotion of the therapeutic effect by the modification of quinine (seven new effective compounds have been obtained). 8. Simplified method of manufacturing disinfectant from pine root oil, 9. Simplified method of obtaining vitamin from rice and wheat germs or rice bran. 10. Examination of the use of Nerium Odorum, a cardiotonic. 11. Manufacture of vitamin from the waste liquor obtained during starch production. 12. Manufacturing method for intestinal medicines by antiseptic butyro- bacteria. Reprints and sample of bacillus Butricds enclosed. XXIX. RESEARCH INSTITUTE OP TUBERCULOSIS RESEARCH INSTITUTE OF TUBERCULOSIS 1005 Shimakiyoto, Kiyose, Kitatama County, Tokyo Director: Dr. Harumlta Oka, This modern appearing laboratory is one of the Important centers for tu- berculosis research. Dr. Oka has headed a 24 man committee which has been re sponsible for giving BCG vaccine to more than nine million people, exclusive of the Army and Navy. This committee has studied a group of 100,000 Japanese receiving the vaccine and another equal sized group in another area which served as a control. 81 M-AB RESTRICTED ENCLOSURE I A), continued Using repeated tuberculin tests as the basis for X-ray examination during a five year period of observation completed in 1943, the following general conclusions were drawn: The 100,000 people receiving BCG in certain areas showed only 50$ of the X-ray evidence of infection seen in the control areas, l/ 4 the clinical evidence of infection and l/ 7 the death rate. In the group receiving BCG, the percentage of extra pulmonary lesions was reduced and the usual peak death rate between 20 to 25 years of age was flattened. The vaccine is made from the original BCG strain brought from France. This culture is maintained on potato bile medium. When vaccine is to be produced, the organisms are cultured two weeks in Sauton's fluid, dried somewhat on sterile filter paper, weighed, suspended by shaning in Saline and gelatin and dispensed for immediate use. The vaccine is outdated after seven days. It is administered intracutaneously in a dose of 0.1 cc which contains 0.04 to 0,06 mg. of tubercle bacilli. It is only given to tuberculin negative individuals. It is not given subcutaneously because of the dan- ger of abscess formation. The age groups most extensively studied have been 15 to 25. Dr. Oka has furnished English summaries of research publications, copies of the publications and reports pertaining to BCG and a stock culture of the BOG culture used to produce the vaccine. (Additional reports on work with BCG vaccine, have been accumulated from other sources and reported under other in- stitutions .) Stock culture carried to Surgeon General's Office by Lt. Col. Henry Cot- ton, on 18 November 45. Reprints are attached. English summaries will be forwarded under separate cover. XXX. WARTIME RESEARCH COMMISSION Board of Technical Science WARTIME RESEARCH COMMISSION Board of Technical Science This appears to be an overall scientific development and research organi- zation which is responsible to the Cabinet. Its governing section is The Chamber for Technical Sciences. The Chamber for Technical Sciences is composed from the Vice Ministers of Cabinet positions and from Technical services such as Aviation, Shipbuilding, and Ordnanace Administrative Headquarters. In all there are 25 members. This chamber decides upon what projects shall be undertaken, allots funds, decides upon priority, and delegates the work. However, the chief of each project is appointed by the agency for which the project is undertaken. 82 RESTRICTED M-AB ENCLOSURE (A), continued Most of the scientists working on WRC projects are also those associated with the NRG, It is said that this results from the lack of qualified men. Reference is made to Research Projects of Army Medical College of Appen- dix "A”, Section 111 of the periodic reports. XXXI. EDUCATIONAL REQUIREMENTS FOR MEDICAL DEGREE, IGAKUSHI EDUCATIONAL REQUIREMENTS FOR MEDICAL DEGREE, IGAKUSHI (From interrogations of responsible members of the Ministries of Education and of Public Health and Welfare and Dr. Tamiya, Dean of Tokyo Imperial University Medical College.) Curriculum requirements are set by the Ministry of Public Health and Wel- fare, and the Ministry of Education sees that they are met by the colleges. SCHOOL YEARS AGE Elementary School 6 Years 6-12 Intermediate School '4 or 5 Years 12 - 16 or 17 (Semmon Gakko or Class B Medical College requires an extra year in lieu to Higher School Course) Higher School 3 Years 19 (Reduced to 2 years during the war) Medical College 4 Years 23 (Reduced to 3 years during the war) Upon graduation from Medical College, a student may apply for license; no special examination is required, Faculties of the Universities, other than Medicine, require three years for graduation. Internship is not required but is customary. Though clinical work is in- cluded, the greater effort goes toward study and preparation of a thesis which usually requires two to three years to complete. Then the student is granted a higher degree, termed ”Hakushi". The Semmon Gakko (class B school) was designed about 1937 to produce med- ical men for the forces exploiting East Asia. Semmon Gakko students entered after Intermediate school. Course was for three years in contrast to four years for the University course. During the war it was reduced to two years. In this manner a large group of poorly educated men was produced. The Japan-, ese say that these men ”lack culture”. The above appears to mention two of the factors tending to lower stand- ards of medicine; 1, The mass production of the Semmon Gakko. 2. The large proportion of University graduates seeking a higher degree rather than going into clinical work. This also tends to ”pad the literature” with worthless papers. 83 M-AB RESTRICTED ENCLOSURE (A), continued APPENDIX "B" Alphabetical List of Persons Whose Activities Have Been Examined NIIGATA AREA XIV NIIGATA GOVERNMENT MEDICAL COLLEGE Name Associated with: AKAZAKI, K. Pathology AMANO ARIYAMA, N. Biochemistry HASHIMOTO, Takashi Dermatology - Dean of school ITO, T. Bacteriology KAITO, R. Bacteriology and Serology KHiARA, K. Pharmacology NAKATA, M. Surgery NOSAKIO, S. Radiology SHIBATA, I. Internal Medicine TASAKA Internal Medicine YASUDA, M. Biochemistry SENDAI AREA XV TOHOKU IMPERIAL UNIVERSITY MEDICAL COLLEGE EBINA, T, Bacteriology KUMAGAI, Taizo Director of T.B. and Leprosy Institute. President of Tohoku University. KATSURE, A. Neurosurgery KATO, Toyojiro Emeritus Prof, of Medicine KOGA, Y. Radiology MASAMUNE, H. Biochemistry MATSUOKA, S. Neuro-Pathology MIKI, I. Orthopedics MUTO, M. Surgery NASU, S. Pathology OSATO, S. General Research (formerly at Kanazawa) SATO, S. Bacteriology TERASAKA, M. Pharmacology YATSUYANAGI, S. Parasitology 84 RESTRICTED M-AB ENCLOSURE (A), continued SAPPORO AREA XVI HOKKAIDO IMPERIAL UNIVERSITY MEDICAL COLIEGE Name Associated with: AMBO, H, Pathology ARIMA, H. Medicine INOUYE, Zenjuro Hygiene ISHIBASHI, Toshima Psychiatry IWASHITA, K. Urology and Dermatology KODAMA, S. Anatomy - Dean of school KON, I. Pathology - Pres, of school MASAKI, Taklo Pharmacology MIKAMI, J. Surgery MINOSH3MA. T Physiology NAGI, K. Pediatry NAKAGAWA, S. Medicine NAKAMURA, Yutako Bacteriology ONO, S. Gynecology OCHI, Sadami Emeritus Prof, of Opthalmology SAETO, S. Director, Hot Springs Re- search Institute. SASAKI, Y. Mycologist SAWATARI, J. Otology SUGINOME, H. Organic Chemistry TAKEDA, K. Pathology UYENO, S. Legal Medicine YAMASAKI, H. Anatomy YANAGI, S. Surgery YASUDA, M. Biochemistry XVII HOKKAIDO IMPERIAL UNIVERSITY HAMADA, S. Bacteriology in Vet. Medicine HANZAWA, M. Applied Mycology ISHIKAWA, K. Veterinary Medicine - Dean ITO, Nubo Ass't• Prof, of Agricultural Chemistry. KOHANAWA, C. Hematology in Vet. Medicine KUROSAWA, K. Obstetrics in Vet. Medicine NAKAMURA, N. Medical Director, Cryologioal Institute. TAKAHASHI, E. Prof, of Agricultural Chem. 85 M-AB RESTRICTED ENCLOSURE (A), continued KANAZAWA AREA XX KANAZAWA GOVERNMENT MEDICAL COLLEGE Name Associated with: AKIMOTO, H. Psychiatry HEKI, M. Internal Medicine HIRAMATSU, H. Physical Therapy INOUE, T, Forensic Medicine ISHIKAWA, T. Pathology ISHIMARU, S. Anatomy ISHIZAKA, N. Dean of school IWASAKI, Ken Biochemistry IZUMI, S. Pediatry KISAMORI, S. Gynecology KUMANOMIDO, S. Surgery EUROCHI, Y. Opthalmology KURU, M. Surgery MATSUDA, K. Otolaryngology MIYATA, S. Pathology NAMIKI, J. Dermatology OTANI, S. Hygiene OKAMOTO, H. Institute of T.B. SAGUCHI, S. Anatomy SAKURAI, Yosio Pharmacy TANI, T. Bacteriology TANINO, F. Internal Medicine UENO, K. Physiology KYOTO AREA XXI KYOTO IMPERIAL UNIVERSITY MEDICAL COLLEGE AKACHI Biochemistry AMONO, S. Pathology ARAKI, Neurosurgery FUJINAMI, A. Pathology FUKITANI, A. Pathology FUNAOKA Anatomy HATTORI, S. Pediatry INOUE, G. Pathology KIMURA, R. Microbiology, Deem of College MATSUMOTO, T. Pathology OGASAWARA, Noboro Director, Leprosy Institute and Microbiological Institute. OGUI, Kikuo Pharmacy SEKI, Takeka Pharmacology SHIMANOTO, M. Pathology TAKAHASHI, Torizo Biochemistry TODA Physiology DNNO, G. Pathology UCHUXNO, S. Director Uohljino Laboratory - Chemistry YAMAZOKI, H. Pharmacology YAMORI, T. Pathology YOMAGUCHI, S. Science, Parasitology 86 RESTRICTED M-AB ENCLOSURE (Aj, continued KYUSHU AREA XXII KYUSHU IMPERIAL UNIVERSITY, Faculty of Medicine Name Associated with; ATSUBO, Kiomi Hygiene and Parasitology FUKUDA, Tokushi Pharmacology EIROHATA, R. Biochemistry IKUI, H. Opthalmology IMAI, Takami Pathology IHOUYE, K. (K. Ishikawa) Radiology ISHIYAMA, F. Surgery J3RINAKA, S. Orthopedics - Dean of school KUSANAKI, G, Medicine MITSUYA, T. Urology MITSUSHIMA, Haruo Public Health NAKASHIMA, Y. Radiology OGATA, D. * Physiology SASAKI, M. E. E. N. T. TAMURA, S. Opthalmology TODA, Tadao Bacteriology and Protozoology UMAYAHARA, S. Obstetrics and Gynecology NAGOYA AREA XXIII NAGOYA IMPERIAL UNIVERSITY, Faculty of Medicine AKUNE, M. E. E. N. T. HAGINO, R. Opthalmology HOTTA, K, Biochemistry KATSANUMA, A. Internal Medicine - Director of Hospital KUCUKAWA, U. Obstetrics and Gynecology KXRAHARA, S. Surgery KOINUMA, Bogo Hygiene KUNO, I. Physiology MIWA, M. Pharmacology NAGAMATSU, H. Anatomy NAKAE, Kyoichi Pediatry NAKASHIMA, M. Opthalmology OGASAWARA, Kazuo • Bacteriology OKADA, S, Internal Medicine OSHIMA, Fukuzo Pathology and Parasitology SAITO, W. Surgery SUGITA, U. Psychiatry TAMURA, H. Dermatology - Dean of school TOGARI, C. Histology UAGURA, S. Orthopedics YAMAHA, K. Histology 87 M-AB RESTRICTED ENCLOSURE (a), continued OKAYAMA AREA XXIV OKAYAMA UNIVERSITY, Faculty of Medicine Name Associated with: HAMAMATO, E. Pediatry HATA, B. Opthalmology HAYASHI, Kanae Physiology HAYASHI, M. Psychiatry HAYASHI, S. Director of Research, Hayashi Pharmaceutical Co., Ltd. INADA, S. Medicine KITAYAMA, K. Medicine MURAKAMI, Sakae Bacteriology NEGISHI, H. Urology and Dermatology OGATA, Masuo Hygiene OKUSHIMA, K. Pharmacology SEKI, Masaji Pres., Japanese Anatomy Society TAEI, Shimizu Biochemistry TAKE DA, T. X-Ray TANABE, Hiroshi Pathology TARO, Kazuno Biochemistry TSUDA, S. Surgery YAGI, Hideo Gynecology and Obstetrics OSAKA AREA XXV OSAKA IMPERIAL UNIVERSITY MEDICAL COLLEGE FUCHUSHIMA, K. Internal Medicine FUSE, N. Internal Medicine IMAMURA, Arao Director, Takeo Institute for Tuberculosis ICHIHARA, Biochemistry KAGIWARA, S. Hygiene KUBO Biochemistry KINOSHITA Director, Cancer Institute - Pathology KUROTSU, T. Anatomy MABUCHI, H. Physiology NICHIZAWA, Y. Pediatry OMURA, T. Forensic Medicine OKAGAWA, M. Pharmacy OTANI, S, Director, Bacterial Chemistry Institute SATANI, Y. Director, Institute of Leprosy TANIMURA, T. Dermatology TAKABAYASHI, H. Surgery TAKAGI, K. Anatomy - Dean of Med. School TANIGUCHI, Tenji Bacteriology - Director, Microbiological Institute YAMAKAWA, K. Otolarynology YOSHIMATSU, N. Gynecology and Obstetrics YOSHIDA, S. Parasitologist (Retired) 88 RESTRICTED M-AB ENCLOSURE (A), continued TOKYO AREA Name Associated with: Institution AIDO, K. Hygiene XIII AKAMATSU, S. Biochemistry XIII AKIYA, Satire Toxicology II ARIFUKA, Sheichl Chemo-therapeutics XI ASANO, Mitizo Biochemistry - Reg, Member I ASHIDA, Taizo XVIII AZUMA, Ryotaro Pharmacology II HASEGAWA, Shuji Biochemistry - Reg. Member I, XI HATSUTA, Y. Ass't. Chemist XII HATASHI, H. Director II HAYASHI, Ryozo Lt, Comdr. IX HAZATA, H. Bacteriology XIII HIRAGA, Minoru Urology and Dermatology III HIRAI, Masahito Maj. Gen. - Deputy Director III HONDA Expert I HOSOYA, S. Serology - Reg. Member I IBUKA, Kenji Lt. Gen. - Director III ISHII, Nobutaro Parasitology - Reg. Member I ISHIKAWA, Mitsuteru Medicine XXVI ISHIKAWA, Tomoyoshi Physiology XI ISHIWARA, Fusao Director, Hygienic Lab. VIII ISIDATE, Morizo Chemical Analysis II INOUE, Takatomo Col, - Biologic Mfg. Div, III ITO, Y. Opthalmology XIII KAMBAYASHI, H. Lt. Gen. - Surgeon General III KAMBAYASHI, Y. Vice Admiral - Director IX KANNO, S. Director, Bacteriological Lab. VIII KAWAI, Samae Captain IX KAWAKITA, Yoshio Bacteriology - Reg. Member I KAWAMURA, S. Botany XII KAWAMURA, Rinya Pathology IV, VI KITAOKA, Mas ami Virology - Reg. Member I KITASHIMA, Taiohi Director IV, VI KOBAYASHI, Rokuzo Bacteriology IV, VI KOBAYASHI, Yoshito Pharmacology II KAGAYA, Y. Forensic Medicine XIII KOIZUMI, T. Parasitology IV, VI KOIKE, K. Dean of College XIII KOJIMA, Saburo Reg. Member - Editor, Journal of Experimental Medicine I KOMINAMI, K. Mycologist XII koyama, t. Clinical Medicine II KURIMOTO, Uzuhiko Bacteriology - Reg. Member I KUSANA, Yoshio Hygiene IV, VI KDTSUKAKE, r. Pathology IV matsuki, m. Lt. Col. - Maxillo-faolal III MATSUMOTO Pathology II MATSUSAKI, Akira Maj. Gen. - Director V MIKI, Yukiharu XVIII MINAMIZAKI, Yushiohi XVIII MINATO, A. Pharmacological Chemistry XIII MISANOU Major - Radiology III 89 M-AB RESTRICTED ENCLOSURE (A), continued Name Associated with; Institution MISAWA, Takayoshi Allergy II MIYAGAWA, Yonegi Reg. Member - Dojinki Society I MIYAKE Pathology II MORIYA, Y. Electrical Engineer I NAGAE, D. Col. - Surgery III NAGANO, H. Parasitology VI NAKAHARA, Waro VII NIATO Major - Biology III NISHIMURA, Iwao Chemo-therapeutics XI NISHINO, Cnujlro Dean IV NOBECHI, Kejio Director XI OGATA, Tomio Serology II OGAWA, Teizo Brain Research Inst. II OMURI, K. Internal Medicine IV OKA, Harumita Director XXIX OSUZU, Hirobunll Col. - Internal Medicine III OTANI, Shoichi Maj. General XXVIII SAITO, S. Medicine Nihon Univ. Med. College SAKURASAWA, F. Director of Hospital Nihon Univ. Med. College SATO, K. Dermatology and Syphology XIII SEO, T. Surgery XIII SHIMIZU, Kentaro Brain Research Inst. II SHOJI, Yoahlharu Opthalmology II SUEYOSHI, Yuji Biochemistry IV SUWA, Keisaburo Col. - Pathology Neuro-psychiatry II, III TAHAKI, Y. Dean XXVI TAKANO, Rokuro Bacteriology VI TAKIGAWA, K. Col. - Orthopedic Surgery III TAKITA, Kikdjl Pharmacology II TAKDRA, T. Pediatry XIII TAMIYA, Takio Dean and Director of Tokyo Imperial University, Medical College. I. II TAMURA, Kenzo Pharmacology II TANIKAWA, K. Hygiene XIII TANAHASHI Col. - Urology III TATSUI, Goro Colonel III TODA, K. Col. - Plastic Surgery III TSUZUKI, M. Surgery II UCHIMDRA, Yushl Director, Brain Research Inst. II UMEZAWA, H. Penicillin Research III, II YABE, M. "BCG" Work III, XV YABUTA, T. Agricultural Chemistry XII YABUTA, Teijiro Director of Research XXVII YAMAGATA, S. Col. - Opthalmology III YAMASHIMA, Hoshika Major III YAMAUCHI, T. Lt. Col. - Director of Research XXVIII YAMAGUCHI, Maseyoshi XVIII YAOI, Hidetake Bacteriology - Expert I YAZAKI XXVI YOKOKORA, S. Rear Adm. - Assoc. Chief of Research IX WATANAHE, Yoshimasa Bacteriology VI 90 RESTRICTED M-AB ENCLOSURE (A), continued APPENDIX "C" Items of Interest Uncovered During the Investigation of Japanese Medical Activities The numbered items are specific ones considered to be of interest to med- ical men in general. This list does not necessarily include all items uncov- ered, for the available literature was incompletely reviewed, due to language difficulties; some items that are not listed may be of interest to certain medical specialties. These numbered items are followed by references, indicating the section of Appendix "A" and the report in which it is mentioned. 1. Dysentery of unknown etiology ooouring on Shikoku, Section I - Report of the same title. 2. Myopic Problems. Section II - Opthalmology Department Section XXIII - Clinical Division - Opthalmology Section XXIV - Opthalmology Section XI - Myopic Problem 3. "Melanophoren hormone" in night vision. Section II - Opthalmology Department Section XXIII - Opthalmology Section IX - Pharmacy 4. Insect Repellents, Section 111 - Pharmacology Department Section XVI - Pharmacological Laboratory (5» 6, & 7) Section 111 - Research Reports - Studies on Communicable Diseases (2b) Section 111 - Research Reports - Other studies, Prophylaxis and Treatment of Malaria, 5, Gas Gangrene Vaccine. Section 111 - Manufacturing Division, Niigata 91 M-AB RESTRICTED ENCLOSURE (A), contlnued 6. B.C.G. Vaccines, Section 111 - Army Medical College - Kanazawa Section 111 - Biologic Manufacturing Division Section VI - Kltasato Institute (1) Section 111 - Research Reports - Studies on Internal Medicine (1). Section 111 - Research Reports - Other studies. Tuberculosis. Section XXII - Bacteriology Department Section XXIII - Clinical Division - Opthalmology Section XXV - Takeo Institute for T.B. Section XXIX Section XVI - Hygienic Laboratory 7. Use of "Cepharanthln" in Treatment of T.B, Section H - Chemotherapeutic Institute Section XIV - Cepharanthin Section XV - S. Ota Section XV - Institute of T.B. and Leprosy Section 111 - Research Reports - Studies on Internal Medicine (2) Section 111 - Research Reports - Other studies, Tuberculosis. 8. Toxic glycidamine from Human Cancer. Section XV - Medico-Chemical Institute 9. National Research Council Projects of Japan. Section XVX 10. Gas Measuring apparatus for Measuring Minute amounts of Nitrogen. Section XX - Biochemistry 11. O-Aminophenol Treatment of Tuberculosis, Section XX - Chemotherapy in T.B, Section XX - Pharmacology 12. Anti-Malarial Drugs. Section XX - Pharmacology - Dirnethozy-8-diethylamino- cthylaminoquinoline. Section XXI - Pharmacology - 2 Methyl-Meroaxto 6 ohlor-9-pyridino 3f2T and 2:3 quinoline chlor hydrate. Section XXI - Tropical Disease - Use of Lowered Oxygen Tension in Treatment of Malaria. Section XXII - Bacteriology - 2-Mothoxv-6-ohlor-9 (4-diethyiamino- cydohexyl-amino-aoridin)• Section IX - Pharmacy - Sulfadibrombenzene. Section I - Parasitology Section 111 - Parasitology Section IV - Parasitology Section 111 - Studies on Internal Medicine (3b & o). 13. Electronic Microscope Studies. Section XIX - (15) Section XXI - R, Kimura 92 RESTRICTED M-AB ENCLOSURE (A), continued 14. Dengue Virus - Cultivation and Vaccines. Section XXI - R. Kimura Section XXII - Bacteriology Department Section I - Dengue. 15. Leishmaniasis. Section XXI - R. Kimura - Treatment of Leishmaniasis with Antimonyl hexonate Section XXI - Pharmacology Section I - Parasitology Department Section II - Colloidal Preparations of Various Heavy Metals (2). Section 111 - Research Reports - Studies in Pathological Fields (5). 16, Schistosomiasis. Section XXI - Pharmacology - Treatment of Schistosomiasis- with Antimonyl hexonate. Section II - Colloidal Preparations of Various Heavy Metals (2). 17. Prosthetic Limb Studies. Section XXII - Orthopedic Department 18. Treatment of R, Prowazekl Infections, Section XXIV - Bacteriology 19. Leprosy Treatment. Section XXIV - Clinical Medicine Section XV - Institute of T.B. and Leprosy Section V - Okuba Army Experimental Station (Neooyamlne) Section VI - Kitasato Institute (1) 20. Wartime Research Commission. Section XXV 21. Education Requirement for Medical Degree - Igakushl Section XXXI Section 111 - Organization of Medical Department, Japanese Army (6). 22. Comments on Medical Education Section XXIII 23. Conversion of Sea Water to Drinking Water. Section IX - Pharmacy Department 24. Intra-Arterial Shook Injection Treatment. Section XIII - Chiba Government Medical College Section XVI - Hojcicaldo - Hot Springs Research Institute 93 M-AB RESTRICTED ENCLOSURE (A), continued 25, Bone Marrow Extract for Anemia. Section XXV - Biochemistry 26. Complement Fixation Reactions in Malaria. Section XVI - Bacteriology Section 111 - Parasitology Section 111 - Research Report - Studies on Internal Medicine. 27. Colloidal Preparations of Various Heavy Metals. Section I - Colloidal Preparations of Various Heavy Metals (1). 28, Dried Biologic and Fat Preparations. Section I - Colloidal Preparations of Various Heavy Metals (3, 4» 5, A 6). Section 111 - Biologic Manufacturing Division Section 111 - Research Reports - Studies on Communicable Diseases (11-l, 2, 3, 4, & 5). 29. Japanese 5 Encephalitis. Section I - Japanese B Encephalitis Section I - Encephalitis Virus Cultured in vitro 30. Infectious Hepatitis. Section I - Infectious Hepatitis Virus 31. "Coramunin"• Section II - Pathology Department (1). 32, Ishihara Color Charts. Section 111 - Clinical Division - Opthalmology 33* Peneoillin. Section 111 - Peneoillin Research Committee Section XII - Nagao Institute 34* Army Medical College Research Reports. Section 111 - Army Medical College Research Reports 35. Studies on Water Supply Apparatus. Section 111 - Research Reports - Studies on Communicable Diseases (IV - 1, 2, 3, & 4). 36. Typhoid Fever. Section 111 - Research Reports - Studies in Pathological Fields (9). 37* Treatment of Sea-sickness and Air-sickness. Section 111 - Research Reports - Studies in the Field of Otolaryng- ology. 94 RESTRICTED M-AB ENCLOSURE I A), continued APPENDIX "D" Alphabetical List of Institutions Screened (All Roman Numerals refer to Appendix "A”) Agricultural Experimental Station * XXVII Army Depot for Medical Materials, Yoga ITVIII Army Experimental Station, Okuba V Army Medical College 111 Chiba Government Medical College XIII Educational Requirements for Medical Degree XXXI Hokkaido Imperial University, Medical School, Sapporo XVI Hokkaido Imperial University XVII Institute for Infectious Diseases (TIU) I Institute of Physical and Chemical Research VII Institute for Public Health II Jikei-Kai University, Medical College XXVI Kanazawa Government Medical College XX Keio University Medical College IV Kitasato Institute for Infectious Diseases VI Kyoto Imperial University XU Kyushu Imperial University, Fukuoka XXII Ministry of Health and Social Affairs XVIII Municipal Hygiene Laboratory, Tokyo VIII Negao Institute HI Nagoya Imperial University XXIII Navy Medical College IX National Research Council XIX Niigata Government Medical College XTV Okayama Government Medical College XXXV Osaka Imperial University XXV Research Institute for T.B. XXIX Technical Intelligence I Tohoku Imperial University, Sendai XV Tokyo Imperial University II Tokyo Imperial University, Government Institute for Infectious Diseases I Wartime Research Commission XXX 95 M-AB RESTRICTED ENCLOSURE (A), continued Institutes Associated With Universities and Reported Under University Heading Morinaga Penicillin Plant 111 Army Medical College - Niigata 111 Army Medical College - Kanazawa 111 Criologioal Institute XVII Aeronautical Medical Institute IV Research Institute for Acid Fast Bacillus IV Institute for Hot Springs Therapy IVI Chemotherapeutic Institute H Medico-Chemical Institute IV Bacteriological Institute H Leprosy Institute HI Uchijino Laboratory for Chemical Research HI Microbiological Institute HV Take© Institute for T.B. HV No Reports Rendered Morioka Medical College Aomori Medical College Tokyo Pharmaceuticl College Tokyo Charity Hospital Showa Isen Hospital Nippon university, Medical College Nippon Medical College 96 RESTRICTED M-AB ENCLOSURE (B) RESTRICTED M-AB ENCLOSURE (B) RESEARCH PROJECTS AND FINDINGS OF THE ARMY MEDICAL COLLEGE, TOKYO TABLE OF CONTENTS Part One - Studies Regarding Sanitation and Hygiene Page 98 Part Two - Studies on Communicable Disease Page 103 Part Three - Studies in Pathological Fields Page 111 Part Four - Studies of Internal Medicine Page 121 Part Five - Studies in the Field of Otorhinology Page 123 Part Six - Studies in the Field of Ophthalmology Page 124 Part Seven - Dermato-Urological Studies Page 125 Part Eight - Studies in Oral Surgery Page 127 Part Nine - Studies in the Field of Surgery Page 129 Part Ten - Studies in the Field of Psychiatry Page 133 Part Eleven - Other Studies Page 140 97 M-AB RESTRICTED ENCLOSURE (B) RESEARCH PROJECTS AND FINDINGS OF THE ARMY MEDICAL COLLEGE, TOKYO Part One STUDIES REGARDING SANITATION AND HYGIENE Anti-cold preparations in the extreme cold region. 1, Manufacture of anti-cold raiment of which particular sections are specially protected. Purpose. As the anti-cold raiment heretofore in use is very heavy and inconvenient to move, we try to increase the efficiency of it by protect- ing particular sections of our body. Resume of methods. There are two sorts of sections in our body, one is sharp and the other is insensible to coldness. We made a special study of moxibustion, which has been utilised therapeutically in Japan, and warmed the moxa points concerned with coldness. Then we measured the respiratory metabolism, the skin temperature and the condition of tremb- ling. Results. We find that the warming of "Kengai" and "Melmon" is most favorable. By warming these two points, our body is indeed protected, but our fingers and toes it has no effect. So we made the portable heater with hand-dynamo for warming of body ends. With this heater we can protect our toes from freezing I}y using it once an hour. 2. Manufacture of anti-cold shoes for ski troops. The aim of this manufacture is as follows; As toe frostbite in the snowed land is chiefly caused by penetration of slush into shoes, we intended to keep them dry. We used for this purpose rubber-covered waterproof shoes, and stud- ied the condition of perspiration and the influence upon protection of the foot which was caused by increase of thermic conductivity of shoes, but its details are still unfinished. Nevertheless, the rubber-covered shoes are worthy of recommendation for frostbite protecting, as there is no noticeable influence of the shoes. ). Study of accommodations for wounded in the extreme cold zones and of camping in snow covered regions. 98 RESTRICTED M-AB ENCLOSURE (B), continued As in the extreme cold and snow covered zone it is insufficient to send camping materials and is impossible to operate on the wounded completely, we tried to find its preparations. Resume of methods. f (1) We examined a snow-cave, which a mountaineer used - if it is available for our troops or not, (2) Portable tent - now under study. (3) We made a hood-shaped tent of the rubber-covered thick clothes with heater tube in order to warm it for treating of the wounded. Results. (1) A snow cave with accommodation for about 10 men is most favor- able. Under 30° C we can encamp in it with only anti-cold raiment. (2) From portable tent we made no records. (3) With above mentioned tent we can keep the temperature about 4CPc under atmospheric temperature of 30° C and are able to treat the wounded. But for practical use there are many to be improved. 4. Study of treatment of frostbite. Concerning the treatment of frostbite of men it is best to soak in warm water the same as our body temperature. But as in a fighting operation this method is practically Impossible, we studied this treatment. Experimental procedure. We took advantage of the above mentioned tent in order to obtain warm circumstances. We generated the damp in the tent. Results. We had to interrupt this experiment at its entrance. Neverthe- less a good result' is promising. 11, Study of supplies, 1. Actual conditions of supplies. Purpose. In war time our supplies were decreasing gradually. We tried to know its actual conditions and to contribute to their development. Procedure. We gathered menus which extended over one week or ten days in different regions and examined the supplied calories and articles of food,. Results. Dec. 1941 May 1943 Dec. 1944 Total Mean Max. Min. 3262 calories 3709 calories 2739 calories 3186 calories 3688 calories 2542 calories 2933 calories 3260 calories 2320 calories Number of the articles of side dish in 10 days. 27-53 36 24 99 M-AB RESTRICTED ENCLOSURE (B), continued 2. Study of reaction of reduced diet on the physical condition. The aim of this study is to know the course of depreciation of our phys- ical ability by reduced diet. Methods, We observed the change of weight and working ability of a sub- ject who was taking 300gm. of rice, Bgm. of sugar and 30gm. of powdered "miso" perday and was working as hard as an ordinary soldier. Results. After a month continuance we find that the weight was decreased 10$, the running time of 200 meters with a 40 kilogram mud-bag pro- longed by 13 seconds (from 60 to 73 seconds) and lifting ability of a 25 kilogram mud-bag decreases from 17 times to 14 times. Afterwards he took the same food with sufficient supplies of vitamins and salts for a month without any decrease of working ability, although his weight reduced by 17$ in comparison with the original one. 3. Elements contained in the food supplies. We examined the elements contained in our foods by means of spectro-photo- graphy. Results. We found that beans contain comparatively many kinds of salts, but the intention of further study was interrupted with the termination of the war. 4• Study of physiological value of protein. We measured the physiological value of protein contained in rice, sar- dines and soya-beans. Method and results. After taking these proteins we compared the absorbed nitrogen within urine excreted one. As to each protein it is the same results with generally convinced, but the physiological value of proteins oonbined with each other is above the original one. 5. Study of the value of hulled rice from the utility view point. From the economical and nutritious view point we examined the former re- sults and made an experiment of absorption of hulled rice and polished rice. Results. (1) If we pay sufficient attention on cooking methods and mastica- tion, etc., there is no particular injury in the hulled rice diet, (2) The hulled rice diet has no value from the economical and nu- tritious view point, if we can supply sufficient subsidiary articles of diet. 111. Improvement of barracks and field positions. 1. Study of continental fortresses. We had the Intention of improving the hygienical equipment in building the fortresses near Manchurian boundary lines. 100 RESTRICTED M-AB ENCLOSURE (B), continued At the fortification planning, we expressed our opinion concerning the medical affairs and contributed to improving them, but not to a sufficient degree. 2. Study of double accommodations in the barracks. Purpose, To know the conditions of environment of double accomodations in summer time. Methods. We examined the environment at night in the cases of either the room being normally occupied with soldiers, or of its maximun accommoda- tion by measuring its temperature, humidity, and 002 quantity. Results. (1) At night while sleeping the average room temperature shows 7° or B°C higher than the outdoors, the humidity 70-75% and the CO2 quantity reached 0.1-0.2%, The conditions of upper sections are far worse than lower. (2) By the maximun accommodation the rising of mercury is far faster than in the ordinary case and so the ventilation was Increased, The humidity and cooling power showed the same conditions with the temp- erature. 3. Investigations of the living conditions in field positions. As we had a little experience of living in field positions, we intended to examine the living conditions in many positions and to take hygienic lead. Procedure. We studied its environment, air conditioning etc. and taught how to settle and build lavatories or drainage. Thus we developed gradually hygienic interest by these examples and teach- ings in actual Improvement gained after observation and study. 4. Elimination of carbon monoxide gas developing while fighting in a cave. » Methods. We studied how to eliminate carbon monoxide gas developed by firing of machine gun and others. Therefore we measured CO concentration in cases of loopholes let open or shut while firing continues and also observed influence on little birds previously settled. Results. Generally speaking the faster we fire, the more carbon monoxide gas developed but never became over 0.2%, because by firing the fresh air came into the room through the loopholes and gave an impetus to ventila- tion. IV. Study regarding efficiency of soldiers work. 1. Suggestions about Investigation of mental efflolenoy of group as unit. Purpose. By this investigation we intended to grasp the mental strength of soldiers at the beginning of their enlistment and to make it a supple- mentary method to bringing up of healthy soldiers. 101 M-AB RESTRICTED ENCLOSURE (B), continued Methods. We simplified the method of Investigation of mental efficiency devised by the psychiatry department, the Imperial Univ. of Tokyo, and used to examined 6000 new soldiers. Results. We devised the more simplified methods, named No. 303. This was also used to examine several forces. We find by means of this examin- ation many feeble minded soldiers who made a record of poorer than 10 mark when the full mark is 30. 2. Study about soldiers’ fatigue. Purpose. We tried to find a good method of Judging soldiers fatigue. Methods. After physical actions such as marching or other soldiers’ work we examined the Donaglo’s reaction with 50 men. Result, We find that the reaction is of no use for our army. 3. Simplified method of physical examination. Formerly we Judged physical strength by the distance of walking with a 120 kilogram burden. So we made this as standard and researched the cor- relation between this result and those of different physica] examinations. Results. We acknowledged that it is best to Judge from the time required in running of 200 meters with a 50 kilogram burden. 4. Study about burdens. Purpose. In order to promote the efficiency of marching we studied about the most fitting weight of burden and its bearing method. Methods. At first we measured the oxygen consumption in cases of walking with burdens of 20%, 25%, 30%, 35%, 40%, 45%, and 50%, of weight. By this experiment we know that the case of 40% is the best burden. The second time we measured also the 0 consumption by different methods of carrying a burden of 40% of weight. This time we find that the closer the center of gravity of the burden comes to our body and the higher it lies the more efficient it is. 5. Study regarding climbing. Purpose. To know the most efficient method of climbing high mountains and steep slopes. Procedure, For mountaineering we selected Mt, Fuji and Mt. Yatsugadake and for slope climbing we use a escalator. Here we measured also oxygen consumption. 102 RESTRICTED M-AB ENCLOSURE (BJ, continued Results. (1) The burden should be under 35$ of body weight. (2) The center of its gravity as low as possible. (3) Legs fasten. (4) Better not to take lodging above 3000 meters high. 6. Study of hygiene of mechanized forces. To know the characteristics of working in mechanized forces and to pro- mote its efficiency we made the following investigations: (1) We made an investigation of mental efficiency, of character, psychological experiment, and physical measuring about chariot men. Thus we sought the correlation between these results to those of firing, managing, and of total records made after termination of ed- ucation. But to our sorrow we cannot find a noticable relation be- tween them. (2) Examined some trial manufacture of electric clothes, esntl-heat undershirts and cap, avoid the heat and cold in chariot. (3) Measured the energy required by soldiers working in the mech- anized force and made a table out of this. 7. Study of the efficiency of the different arms of the army. For reference to the soldier training we measured the intensity of diff- erent arms. Methods. We gathered expiratory air in Douglas's bag while his actions we analysed by means of Haldane-Koizumi's method and calculated consumed calorie out of respiratory metabolism. This result is used as a table of efficiency and as material for education. Part Two STUDIES ON COMMUNICABLE DISEASES I. Prevention of malaria. 1. V Investigations of malaria mosquitoes. To prdaote the knowledge of the medical officers about malaria prevention, illustrated tables for the anopheline identification had been prepared. These tables were all burnt to ashes before distribution. 2, protection measures against mosquitoes and the studies of anti-mo- squitoes and the studies of anti-mosquito chemicals. 103 M-AB RESTRICTED ENCLOSURE (B), continued a. Anti-larvae chemicals, Phenothiazine and parisgreen are reported to be more effective than the infusion of tobacco leaves (about 20$) and the feces of the horse. b. Anti-mosquito liquid. Anti-mosquito liquid we made proved effective about 6 to 8 hours after application, and has been used by the Army at large. 3. Cultivation of malaria plasmodla. Kept in the refrigerator, birds-malaria plasmodla in the defibrinated blood of infected birds proved to be alive about 5 days. 4. Prophylactic use of malaria specifica. According to the statistical studies of oral prophylactic measures done by the army in the field, CHININUM HYDROCHLORICUM, taken 0,2 gram every day, seemed to be able to reduce the cases of manifest malaria Infection by 30 to 50$. But this observation, being based on the Individual reports of soldiers, may lack in the exactness of laboratory experiment. Combined application of atebrine and plasmochin with chinine, seemed to be more effective, but not having sufficient cases, it cannot be assured. Studies on the improvement of vaccines, 1. Dry vaccine. Typhoid and 6 other kinds of vaccine were prepared dry and the virulence was reduced to 1/20 of the ordinary liquid vaccine, where the growth of immune body was proved better. Adopting the method of Dr. Miyagawa, Professor of the Tokyo Imperial Un- iversity, dry vaccine was prepared by drying, in lower temperature, the bacterial emulsion which was made by adding double quantity of glucose. The period of observation is not long enough to assure the prophylactic effect on the soldiers. Kinds of dry vaccine prepared are as follows; (1) Typhoid Para A*-B mixed vaccine (2) Typhoid vaccine (3) Paratyphoid A vaccine (4) Paratyphoid B vaccine (5) Cholera Vaccine (6) Plague vaccine (7) Epidemic cerebrospinal meningitis vaccine (8) Typhus vaccine (9) Tuberculosis vaccine (10) Smallpox vaccine (11) Wound infection vaccine (Tetanus and gas gangrene) 104 RESTRICTED M-AB ENCLOSURE (B), continued 2. Dry B.C.G. Emulsion of B.C.G. in 5% lactose solution, will be frozen and dried in vaocuum. This was proved effective about 5 months, while the B.C.G. in liquid form will reduce its antigenicity within 7 days. Tuberculin reaction on both animal and human bodies showed this preparation not inferior to the fresh prepared B.C.G, 3. Dry smallpox vaccine. Glycerin vaccine used hither to has been expected effective only 2 months after manufacture. To prolong the period of preservation, 0,1% trypaflavln solution was added to the vaccine and dried after freezing. No change was seen in quality and the period of preservation was prolonged to 1 to 2 years at least. 4. Dry gas gangrene vaccine (Aluminous toxoid). Applying the method of Dr; Hosoya, Professor of the Tokyo Imperial Uni- versity, the liver-liver-Bouillon culture was changed aluminous toxoid and was dried in a vacuum. No uncomfortable reaction was seen and the antibody was proved to have been well produced. This preparation was used only in certain areas of the field and the ef- fect on the inoculated soldiers has not been reported. 5. Typhus vaccine. We could not succeed until today, in preparing a large amount of typhus vaccine made of Rickettsia prowazeoki, while Rickettsia manchuriae vaccine was easily prepared by utilizing the lung (mice) and peritoneal tissue. Lately, repetition of culture 7 generations from egg to egg brought us success, in getting good amount of R. prowazeoki. 0.1 to 0,2 cc of Blood of an infected guineapig will be Injected into the yolk sack of the egg which has been Incubated at 37°G for 7 days, R, prowazeoki will be rarely found in the first egg, and with the repetition of culture it will increase its quantity. Yolk sack, chorioalantols membrane and foetus (excluding eyeblub, bill, wing and leg) will be measured and ground, then* by adding physiological saline solution which contains 0.1% formalin and 0.3% carbolic acid, 5% emulsion of the tissue will be prepared, Centrifugallzed at 3000 rot. per minute this emulsion will produce the upper clear layer which is to be used as vaccine. Dry vaccine will be prepared. Yolk sack, chorioalantols membrane and foetus will be taken out and the same amount of physiological saline solution with 0.2% formalin will be added, then ground to gruel and centrifugallzed. 105 M-AB RESTRICTED ENCLOSURE (B), continued Upper clear layer will be mixed with glucose and dried. This preparation shows distinguished antigenicity in animal-examination and its period of preservation will be 2 to 3 years, while in the liquid form can be preserved only 1 year in a dark, cool place. Having had no epidemic of typhus among us, we have had no chance of assuring the effect. 111. Other miscellaneous studies. bacillus. With the aim to detect open tuberculous patients in the Army, the follow- ing researches have been tried. a. Comparative studies of culture media. Lowenstein, Petroff and other culture media have been studied and Oka-Katakura culture medium was proved to be the best. Oka-Katakura culture medium: I solution KH2PO4 5.0 gram 5,0 gram Ajinomoto 10.0 gram Aq. dest. 1000,0 gram warmed 30 minutes at 100° C. I solution 100.0 cc glycerin 6.0 cc 2% malachite green 6.0 cc Egg (whole eggs 4, yolk 1) 200.0 cc Distributed to the test tubes and sterilized on first day at 85° C 40 min., 2nd and 3rd day at 80° C 40 min. b. Substitute of tuberculous bacillus culture medium. Shortage of eggs compelled us to look for some other material which could be used in its place. Infusion of soya beans was found to be usable, though a little in- ferior to an egg itself. Colonel Masuda succeeded in separating the tuberculous bacilli from the patient’s sputum, using the medium composed of water solution with serum (10%) and glycerin ($%). This cannot be applied for the successive culture. c. Non-pathogenic acid-fast bacteria in sputum. In certain examinations of 1000 soldiers we found 18 strains of acid- fast bacteria, of which 12 were proved non-pathogenic. d. Simple method for collection of tuberculous bacilli in sputum. Sputum will be mixed with spit and will be incubated about $ hours at 37° C (autolysis) to produce sediment at the bottom. This sediment will be used for microscopic examination, even if a little inferior to that made by ordinary method of bacteria collection. 106 RESTRICTED M-AB ENCLOSURE IB), continued 2• Culture media for Salmonella. Because of the difficulty in getting bile, we tried to use 1% glucose solution (in cases when we have no glucose, sterilized water only can be used also), by adding the blood to be examined l/ 2 to l/ 3 volume of the solution (or sterilized water). This medium will be well used, though a little inferior to the ordinary bile medium. 3. Cholera vibrio. Differentiation of cholera vibrio from the non-pathogenlc vibrios has been studied and Pfeiffers phenomenon is concluded to be the only method for this purpose. 4. Penicillin. By the experiment to use infusion of soya beans in place of glucose and pepton in Zapeck-Dox culture medium, we could presume that the amount of glucose and pepton in this medium could be reduced. But this experiment was given up this August. Raw penicillin made of this medium showed one time about 500 times as much anti-staphylococcus value as that of the ordinary media. IV. Studies on water supply apparatus. 1, Materials for filtration tubes and burning process of porcelain fil- ter. Diatom earth is the main component of the filtration tubes. The quality of the diatom earth in respect to fitness for filtration tubes, will be determined by the quantity of meloslra contained. We made comparative studies of the diatom earth produced in various dis- tricts of Japan and found well qualified earth in Hokkaido and Korea, Mixture of Diatom earth (70%), clay (20%), and orthoclase (5-10%) makes the most efficient filtration tubes. Burning must be done at 1160° C at least. 2. Examination of filtration tubes, their preservation and chemical treatment. Inspection and measurement will be followed by an examination of the abil- ity for filtration of water and detention of bacteria (B. prodigiosus), Water bubble examination must be done also, by sending the air at pressure of 1 kg. from inside the tube. Explanation. The bubbles coming out of the surface will indicate the fis- sures or the defects in the wall of the filter. As a result of these examinations, 1+5% of the products was used to be dis- qualified. To prevent the growth of mould on the surface of the tube, treatment by CaCl2 solution with carbolic acid was applied. 107 M-AB RESTRICTED ENCLOSURE (B), continued 3. Handling of filters. Kinds of filters now in use in the Army are as follows: Type Size & Conveyance Capacity p.h. Weight Distribution A. 20 Filtration sets Truck 36 kiloliter 5 tons 4 to each Divs. B. 2 Boxes Transport vehicle 1000 liter 100 kgram 1 to each battalion C. 2 Boxes Horseback 700 liter 70 kgram 1 to each company D. 1 Box Human back 100 liter 20 kgram 1 to each section E. Personal equipment 20 liter 5 kgram 1 to each squad Filtration waste, deposited on the surface of the tube, will be brushed off for 3 to 5 minutes after each filtration process, so as to prevent the lowering of capacity of filtration. As the substitute for the metal part of the filtrations set, various kinds of wood have been applied in vain. 4. Instruments for conveying water, (water distribution in the field) For transportation by trucks, a water bug (capacity 180 liter) or a wooden vessel, and for transportation by personnel a rucksack, bamboo stem and other various kinds of bottles were used. Y/aterbugs and other vessels were furnished with nozzles through which the water was distributed to the soldiers. In certain areas, to provide many soldiers with water at one time, 2 meter long bamboo stems with 10 nozzles were applied. Studies on disinfection processes In the field. 1. Field disinfection vehicle. Composed of 2 trucks - A and B, A Truck Water vessel (capacity 1 cubicmeter) boiler*, turbin pump for spray shower. B Truck disinfection bug hot air producer (run by gasoline) Process of disinfection for personnel (1) disinfection (2) bathing for clothing (3) steam sterilization (dried by hot air) for horses and vehicles (1) medicament disinfect- ion Capacity 100 personnel p.h. (in summer, 200 p.h.) 2. The effect of substitute of disinfection chemicals. Nothing to be especially reported, 2.5% lysol, 5% carbolic acid, milk of lime, 1% formalin, and 0,1% corrosive sublimate have been applied in the usual way. 108 RESTRICTED M-AB ENCLOSURE (B), continued 3. Atomizing and vaporizing disinfection. a. atomizer (nothing new) Pump is fixed to the vessel and run by 2 personnel, as the disinfect- ant lysol and carbolic acid will be used. (This is contained in the Booeki-kyuu-suibu-ikyuu set for the prevention of communicable dis- eases in the field, which is provided to the G.H.I. already.) b. Steam sterilization. Field sterilizer is planned for this purpose. Iron pots, drums cans and other steaming baskets were used in the field. 4. Formaldehyde. Nothing has been practically planned. Before the war formaldehyde was used for the disinfection of rooms, books and clothing. Sometimes it was used as 1$ water solution also for the disinfection of rifles and other utensils. 3. Insecticide. (D.D.T, manufacture and examination of D.D.T.) In Japan D.D.T. was first made by the pharmacological department of the Army Medical Academy and later was manufactured by the Dai-ich-seiyaku- kaisha, trade mark of which is P. The examination was done in respect to the insecticidal effect of D.D.T. powder for lice and flies, 10 to 20 minutes after exposure to the powder, insects showed certain changes in movement and 2 to 3 hours later or sometimes $ to 6 hours later all of them were killed. Concerning the mosquitocide effect we have had no experiment. To econo- mize, we tried to use a mixture composed of 10$ of D.D*T. and 90$ of mag- nesium carbonate or magnesia usta. Since, by governmental order the nec- essary materials for this preparation were directed to meet the other urgent demands of war, both manufacture and experiment were given up. VI, Miscellaneous. 1. Dry serum (convenient for transportation and can be preserved 2 to 3 years.) Applying the lyophile process of Prof, Flosdorf and Mudd, U.S.A., we suc- ceeded in drying the blood type test serum, bacteriological diagnostic serum, serum for the treatment, and plasma for the transfusion. 2. Examination of water. V/e assumed 3 ways for the examination of water in the fields, a. Immediate water test. This test is only a simple toxicological examination for HCN, HgCl, and As. Test paper in the set reacts to a toxicant of a density of 1/100,000 and will be preserved 1 year. 109 M-AB RESTRICTED ENCLOSURE (BJ, continued b. Field water test. Simple examination for the temperature of the air and water, turbid- ity, chlorine ion, ammonium, nitric acid, nitrous acid, hardness of water and isolated chlorine. The set for this test will contain. Object to be examined Materials for examination CL Silver chromate powder, comparator Ammonium Nessler’s reagent, Seignette salt powder Nitrous acid Gries-Romin reagent, Nitric acid Metal magnesia Hardness Medical soap Isolated chlorine Orthotoluidine solution c. Thorough (precise) water test. To secure permanent water resources all kinds of examinations of the quality and quantity of water including chemical and bacteriological examination must be done. Materials for this examination are contained in the "Booeki-kyuu- suibu-ikyuu" which is already provided to the G.H.I, 3. Studies on the water-supply on Iwo jima Island. Having no drinking water resources on Iwo jima, the Army was obliged to drink the mineral water, the magnesia in which cause many cases of diar- rhoea. Titan yellow was used for the quantitative analysis of magnesia. To get rid of Mg the following methods were applied: a. Lime method, A certain amount of quick lime, equivalent to that of Mg in the water, will be added to the water and then the water will be filtrat- ed. Ca(OH)2+MgS04=CaS04 + Mg(OH)2 b. Baryta water method Either Mg or or both will be taken out. Only the medical offic- ers are allowed to use this method, because of the toxicity of Ba to the human body. Ba(OH)2 + MgS04 = + Mg(OH)2 c. Lime and Baryta water method, a. and b, combined. d. Others, About 5 to 6 times quantity of rain water will be added to the min- eral water. 110 RESTRICTED M-AB ENCLOSURE (B), continued We assume that these methods were applied in the island and must have been useful, but the Army there having been annihilated, we have no exact knowledge about the result. 4. Studies on the substitute media. The want of food caused a shortage of materials for media. a. As a substitute for bouillon, the residual liquid produced by the process of "Tofu" manufacture proved to be amply useful. b. Infusion of bones and skins of fishes (10-20%) will be also useful, Part Three STUDIES IN PATHOLOGICAL FIELDS 1. Field Autopsy Car A field autopsy car was built for the purpose of carrying out autopsies in the field in good conditions. It was planned in 1937 and finished in 1939. Only one set was made, and sent to Middle China, but no report concerning its ability was obtained. The autopsy oar consisted of two trucks. The first car is for tissue research, simple bacteriological and biochemical research, and to this oar a tent is pitched to carry out autopsies under. The second car used to transport various stock for autopsies as well as collected materials. About 200 autopsies can be done without any supply. 2, Pathology of War Injuries. The following cases of war injuries which were examined in a certain period after the injury, are of Interest. (1) Brain shot. Out of 30 brain injuries examined, three died due to injuries other than head injuries. Brain injuries were found as the direct cause of death in the rest. Table 1. shows the outline of the observation. (2) Spinal cord lesion and renal stone. Much attention was paid by workers in this field to the combination of kidney stone with spinal injury or with fracture of femur and with head injury (Bastiian, Smith, Lediard, Bick, Oliver, Muller). We found also 24 cases (68$) out of 35 autopsy cases of spinal cord lesion, (a) The regional relation of spinal cord lesion to the kind of am- munition. The lesion (a considerable number of its cases was caused by bullets) occurs mainly in thoracic portion and otherwise in the lumbal portion. M-AB RESTRICTED ENCLOSURE (B), continued (b) Renal stone and renal abscess. We observed 24 cases out of 35, where urinary calculus exists micro- scopically in urinary passage. The portion of its existence is as follows; pelvis of kidney urether urinary bladder total + ■+ + 9 + - + 12 — + + 1 4- 2 The quality of calculus varies and the size is from a grain of rice to renal gravel, but sometimes larger than the tip of the thumb. It must be taken into account that we had 23 cases of renal abscess out of 24 cases of nephrolithiasis observed. (c) Histological consideration in the formation of renal stone. There are so many different views that it is difficult to determine the cause of formation of stone in urinary, especially in renal pas- sages. In 24 of the 35 oases, calculus was microscopically observed, being further recognized histologically as deposit of lime in renal parenchym. We had 20 cases of spinal cord shot as the direct cause of death. Examination of the location and the grade of injuries, in addition to the tracing of advancement of degeneration leads to the hodologi- cal studies. (3) Lung shot. We studied 26 oases of lung shot (period maxim. 1145 days, min. 59 days, average 465 days after injuries). According to past literature it had been mainly discussed in connection with the causes of death and histological studies in shot canal. But it is necessary in Japan to research its influences upon tuberculosis. (a) The canal of lung shot usually heals well to a scar except for particular complications and we recognized no complete regeneration alvaoli in the scar which Borst had once reported. (b) The abortus is enclosed with thick connective tissues and divid- ed into two parts, one sticking firmly together and the other packed by capsule. The capsule is divided histologically into three strata and rarely causes purulent changes, (c) - In 12 of 26 cases of lung shot we recognized tubercular changes in lung parenohyn. (d) We observe rarely that tuberculosis reappears directly following lung shot. ' The correlation of lung shot with lung tuberculosis may be very close to the state of existed tuberculosis. 112 RESTRICTED M-AB enclosure (b), continued (e) On the contrary there were 7 cases of formation and reapperance of tuberculosis indirectly caused by lung shot, and 6 cases of them complicated the empyema. It should be noted that "circulus vitiosus" was found between the chronical empyema and the lung tuberculosis, (Literatural Societatis Pathologlcae Japonica liber 33, 1942) (4) Heart shot It is evident that a soldier whose heart is shot dies instantly or very rarely survives. We had 3 rare cases of this kind and found in one of them a piece or broken shell remaining in the heart muscle. case number 1 2 3 days of process 24 38 1023 kind of shot wounds direct pericar- dial shot indirect pericardi- al shot a piece of broken shell re- mained beside peri- cardium direct heart shot a piece of broken shell remained in heart muscle pericardium 1, purulent pericarditis 2, purulent- blooding fluid 500 cc 3* defect as large as soy- bean 1. fibrinous peri- carditis 2. adhesion between pericardium and pleura 1, shot wound of pericardium (?) 2, remarkable thick- ening of peri- cardium heart 1. purulent pericarditis 2. atrophy and vacolde gene- ration of heart muscle 1. fibrinous thick- ening of peri- cardium 2. atrophy of heart muscle 3. intima not abnormal 1. thickening of heart-pericardium 2. little atrophy of heart muscle 3. cicatrization and lymphcellular in- filtration around broken shell 4* intima not ab- normally 113 RESTRICTED ENCLOSURE (B), continued (5) Aneurysm Lieutenant-Colonel Fukuda studied aneurysm in detail clinically and also pathologically. Outline of 6 section cases of them are as follows: case number days of process nature of aneurysm size of aneurysm wall of aneurysm cause of aneurysm 1 253 traumatic aneurysm {aerta abdominalis) as big as a fist connective tissue rupture of aneurysm 2 196 traumatic aneurysm (a, axi- llaris) as big as a fist connective tissue brain-embolism 3 86 traumatic aneurysm (a, ver- tebral! s) as big as a hens’ egg connective tissue rupture of aneurysm 4 165 traumatic aneurysm (a, sub- clavia) as large as head of foetus connective tissue haemorrhage after operation (?) 5 126 traumatic aneurysm (a. sub- clavia) as big as a hens’ egg connective tissue rupture of aneurysm 6 238 traumatic aneurysm (aorta thoracica) as large as man’s head connective tissue weakness 114 RESTRICTED M-AB ENCLOSURE (B), con tinned (6) Intestines Most of intestinal injuries are found in cases of instantaneous death on the battlefield but we have several cases of healed liver, spleen and kid- ney shot by cicatrization. case number 1 2 3 days of process 253 627 clinical diagnosis penetrative gun- shot wound of thorax penetrative gunshot wound of abdomen scarlet fever case of death rupture of abdo- minal aneurysm death through sickness scarlet fever part of shot wound left lobe left lobe between left and right lobe histological state of liver remarkable cicat- rization of shot wound, embolism of gall in cicat- rical tissue remarkable cicatrization of shot wound cicatrization of shot wound in- filtration of neutro- and eoslnophilous leucocyte in Glisson’s sheath (7) Legs and arms. We have been studying the end of amputated limbs or pseudoarthros, neuroma at the amputated nerve ending and the recovery of nerve function, but it is regrettable that many materials were lost during our study. 115 M-AB RESTRICTED oase number days of process cause of death purlent Inflammation or absoess of brain substance purulent meningitis purulent inflammation i 40 purulent inf- lammation of brain + 4- + 2 81 purulent inf- lammation of brain + + + 3 149 purulent inf- lammation of brain + 4 113 brain aboess +■ + 5 228 brain aboess +• + + 6 23 brain aboess +■ + 4- 7 176 brain aboess 4* + 8 266 brain aboess •f + 9 317 brain aboess +■ + 10 116 brain aboess 4- - - 11 141 purulent inflam, and hemorrhage of brain + 4- hemorrhage 12 108 purulent inflam, of brain + + + 13 178 purulent inflem. of brain + + + 14 338 brain aboess + + + 15 387 purulent inflam, of brain + 16 365 purulent inflam. of brain .+ - - 17 197 purulent inflam, of brain + + - 18 91 purulent inflam, of brain + + + 19 206 purulent inflam, of brain + + + 20 343 purulent inflam, of brain t- + - 21 444 brain aboess + + - 22 91 softening of brain substance + 4- + 23 1 213 purulent inflam, of brain + + 24 387 purulent inflam. of brain + 4- + 25 135 purulent inflam. of brain + + - 26 123 purulent inflam. of brain + - 27 56 brain aboess + - - 28 206 purulent inf lam. (pleura, bladder kidney) + - - 29 99 8 Miliary tub- erculosa - - 30 553 gas phlegmons +■ - - 116 RESTRICTED M-AB ENCLOSURE (B), continued 3* Pathological Studies of Frostbite. We did research on the pathology and treatment of frostbite of soldiers in the cold-regions. The first research on tissue was attempted in connection with amputated frost-bitten limbs of soldiers, but no result was obtained from it, and then basic experiment was made under a unique condition. We put a rabbit in a small glass chamber and placed dry ice directly on her hind leg for 30 minutes. The affected part turned into anemic pallor, then after 3 hours changed to congestive flush and edematic swelling. And after 12 to 24 hours it became dark purple and necrotic. After 72 hours the demarca- tion line was formed at the place which was nearer to the heart than to the affected part. Thereafter the necrosis progressed and bone was exposed and amputated along the demarcation-line. When the affected part was irradiated repeatedly by ultra-red rays, the demarcation line moved to periphery and ne- crosis become small and light. These facts showed that the formation of necro- sis was due not only to the death of cells through the cold, but to cramp of the vessels. 4. Pathological Study of Burns. The problem of burns is already well-known, but recent air-raids and bombard- ment entailed a rapid increase in patients, and consequently more elaborate study became necessary for their treatment. We have studied with the help of Dr. Fukuda (Professor of Surgery, Tokyo Imper- ial University). First fundamental pathological change of tissue is the intoxical changes of vessels and all other changes in each organ are considered as secondary changes. Capillary changes are collapse, rise of permeability for the plasma, leakage of red blood corpuscles and consequently perlcapillary oedema which contains a great deal of albumen. There fore, the space between capillary and parenchym- atous cells is magnified. The changes of small vessels are oedematic swelling of the wall of vessels, myolyse, leakage of red blood corpuscles, formation of toxical thrombus. The perivascular oedema and the wide space between capillaries and parenchyma- tous cells bring about anexemia of tissue and then necrobiosis of parenchyma- tous cells and their disappearance. First organic changes is encephalitis, hepatitis and nephrosis. Myolyse of myocard is a post change. Generally these changes of burns very much resembles the sun stroke and consequently we consider sunstroke as the burning of organs. (Sooietatis pathologicae Japonicae, Liber 33* 1943). 5. Pathological Studies of War Diseases. Kala-azar: The disease, Kala-azar, which could hitherto rarely be observed outside limited areas, has been observed In abundance since the Chinese affair. According to the pathological studies on twenty-five cases at the Pathological Faculty, A.M.S., what was found hardly differed in general form the reports by Marchand, Ledlngham, and Christophers. Although it was clear that in many cases the causes of death were complications, it was necessary to re-examine the causes of death of those who died apparently due to marasmus. It is worth paying special attention to the fact that in these cases, intense regressive degenerations in the liver involving wide-spread degeration, necrosis and des- olation of liver cells were observed. However, it has not been clarified as M-AB RESTRICTED ENCLOSURE (B), continued yet whether such degenerations were due to chronic poisoning of antimony prep- arations or based on the toxic action of Leishmania donovani. (Literature: Societatis Pathologicae Japonicae Liber 33, 1942) Malaria; Many valuable results have been obtained from pathological investi- gations in Japan, the number of which since the outset of World Y/ar II has in- creased in a leap to a very high figure, and even many cases of malaria tropica have popped out to be ours for the observing. According to the studies made by V/atanabe and Tauchi abroad, whose findings do not vary much form the de- scriptions of past literature, it should be noted that in the field of the brain remarkable cases of typical malaria granulom of Durck, Prof. Wake and others were few, and fibrinous degeneration of coat of vessels and "Entmark- ungsherd", mainly in the area of occiput, were observed. According to recent findings in the domain of pathology, it is suggested that causes of death in malaria cases be reexamined in the light of identification, distribution and morphology of plasmodium in corpses. Journal of Japanese Army medical Corps 344. 1942, 359. 1943. Malnutrition; In view of the fact that many cases of a disease with a kind of marasmus as its main symptom were experienced during the Chinese affair, our faculties have made researches along the line of determining its nature and finding out counter-measures against the evils of the disease. Pathologically speaking, most cases of so-called malnutrition are due to in- testinal diseases caused by amoebic and bacterial dysentery and trichomonas. According to the writer’s way of classification of the disease basing on its genetic factors, it can be divided into two groups, one with ulcers in the instestine and the other without, the former being further sub-divided from the histological viewpoint of ulcers into one with new and slight ulcers and one with serious ulcers. In bacteriological studies we did identify neither dysenteric bacilli nor entamoeba. Since the War of Great Eastern Asia, this disease has been observed in southern territories, and malaria has been taken for an important, fundamental disease for malnutrition, but seeing pathologically, it is regarded as a type of disease with total atrophy based on nutrition failure. However, its exact /pathological nature is yet unknown. 16. Pathological Studies on Sudden Death, (1) Studies on the heart tissues in various diseases. We found disturbances of the heart, especially cell infiltration in the heart muscles, in cases of the sudden death. We investigated about 380 autopsy cases, 1938-40, and concluded as follows: (a) In the cases of tuberculosis, one finds often lymphoid cell in- filtration and it does not form an intermediate link to the tubercu- lous tubercle. The Aschoffs tubercle or its similar granuloma changes directly to the tuberculous tissues, (b) In the oases of infectious diseases except tuberculosis and of some others: (i) In the oases of cholera, scarlet fever, Kala-azar, pneumo- nia and uremia, one finds the infiltration of the neutrophile or cosinophile leucocytes, but they are not of an enormous grade- (ii) Round cells, especially lymphatic cells, are often found and peculiarly in the case of well conditioned men. 118 RESTRICTED M-AB ENCLOSURE (B), continued (iii)We found the typical Aschoffs tubercles in one case of rheumatism, entirely similar granuloma in one of uremia, and regarding scarlet fever it differed a little. The granuloma in the case of Kala-azar is without connective tissue, so it is quantitatively different from that of rheumatism. (2) Studies on the cause of sudden death. Studies on sudden death in the army differ from that of the old forensic medicine and offer many interesting questions to studies on the constitu- tion etc. According to the Japanese Army statistics of accidental death, so-called sudden deaths numbered 10 cases in 1937 and 12 cases in 1938. We had 27 autopsy cases, and 10 of them died in bed and 7 died during or shortly after heavy work. Autopsy shows that 10 cases had disturbances of the heart, which were mainly acute or chronic inflammation of the heart muscles, 3 cases of brain lesion, and 2 of the endocrine organ lesions. Other 12 cases had no remarkable changes except persistent thymus. (Liter- ature: Journal of Japanese Army Medical Corps, 1943; Societatls Patholog- icae Japonicae Liber 30, 31, 1940, 1941.) 7. Studies on Tuberculosis, (1) Pathological study of t.b. in army. The pathological studies of tuberculosis in army have to be linked with matters, namely initial and reinfection, especially because there are many new recruits who give a negative result in Mantoux-reactlon. It is so important a problem to study the modes of infection, frequency, and degree or type of disease etc. that we have collected as many mater- ials as possible. Meanwhile we also tried to get a collection of the cases in primary pulmo- nary comple, in which an investigation about the frequency and type of illness was made in detail. But in the course of our study, all materials were burned. Accordingly we could not arrive at a conclusion", but merely followed the following two important guesses; (a) There are many tuberculous cases of perfectly chronic processes. (b) Relatively many cases of infantile tuberculous type in the sol- diers, is developed from a primary tuberculous foci. (2) Treatment and histopathologlcal figures. As soon as a few new prophylaxises or medicines were prepared in our scientific circle, we tried to determine its effect through animal experi- ments, but no new information. But recently, as a precautionary measure serotherapy seems to be the best one, and in the Initial stage of tuberculosis some chemotherapeutics may be useful. While for more serious cases than ordinary ones, only surgical applica- tion is responsible. 119 M-AB RESTRICTED ENCLOSURE IB), continued IS. Patho-Anatomical Studies on Kashin-Beck Disease. About one hundred years ago Kashin-Beck disease was discovered in Siberia, For more than ten years it has been discovered without member in Manchuria too. Prof. Ogata at Tokyo Imperial University has turned his attention to the rela- tion between this disease and abnormality of internal secretion in the salivary gland, and to drinking water in an aetiological sense. Also he expounds that there may be a fear of suffering from the sickness if a Japanese stays for a long time in Manchuria; therefore we have helped him in the work. Kashin-Beck diseases are epidemics which are distributed from areas neighboring the south- ern part of Lake Baikal through Sanga to south-east Manchuria, especially densely (60-80$) all over Toohendo, further more extended to north Korea. The variation appears in the joints in boyhood, and halts the condition for life of which grows less serious at the age of about twenty years. In initial stage there are the subjective symptoms such as a slight articular pain. In serious cases the variations appear in all joints, in most serious cases patients become pygmy. These are "Artrltls deforciant" in boyhood from the patho-anatomical point of view, large ulceration in a cartilage and "Osteopo- rosis" in a epiphysis. On this etiology there are conflicting theories, vitamin - A deficiency (Taka- mori), iron in drinking water (Hieda), hormone disturbance (Ogata). As these theories, except Ogata’s, are concluded in outline, we have been studying to- gether with Prof. Ogata. Prof. Ogata pays attention to the manifest desolation in intercalary portion of parotid salivary gland which secretes hormornes that the disolution of salivary gland may be due to some organism in drinking water. 9. Typhoid Fever. Typhoid fever is one of the most frequent infectious diseases in Japan, even in peace time. In this war many victims of typhoid fever had high mortality and the character- istic features of so-called "war typhoid fever" in Japanese Army. It is a very interesting and important problem to study the cause of death, modes of infection and immunity, in order to prevent and cure this disease. In Japan there is a foundation of Keitokukai, as an institute for typhoid fever. Many explorations about its pathological anatomy are mainly made by the above mentioned laboratory and by Prof, Suzuki, in the pathological laboratory of Tokyo Imperial University. Our most important purpose lies in systematic studying, with the advantage of course of illness, of all the non-specific lesions in various viscerae and tis- sues, and at the same time, in one which has a connection with the searching for the histogenesis about the so-called "Typhoma". According to the results of patho-histological investigation on about 100 cases of typhoid fever, the typhoma may be, in early stages recognizable in liver, spleen, bone-marrow, lymphatic glands, kidney and lung etc. With the progress of the course of the disease, the typhoma shows various al- terations, for example, degenerative and reparative ones. All typhomae in reconvalescent stadium seem to disappear completely except in the spleen, in which a frail granulation tissue is left. 120 RESTRICTED M-AB EfvCLOSURE (B), continued It is also a very interesting question to study the relation between typhoma formation and immunity, but obscure as yet experimental pathology. About the modes of infection we have no certain conclusion, but recently we had some rare cases, which had no lesions in the intestinal tract. There is ample scope for further investigation about the state of bacteriolog- ical localisation in various tissues. Part Four STUDIES OF INTERNAL MEDICINE 1. Prevention of Tuberculosis by Means of B.C.G. (a) On inoculating persons with anamnesis of tuberculosis and tubercular animals with 8.C.G., it was found that their sensibility was to the same degree as that shown in the case of the tuberculin test now in widespread use (Kosaka, Journal of the Army Medical Corps No. 374 - Hereafter abbrev- iated J.A.M.C.). Hence it can safely be said that B.C.G. inoculation is not dangerous without previous tuberculin test. (b) By means of the time of appearance and disapperarance of erythema in tuberculin intracutaneous reaction and the highest stimulation value of tuberculin allergy, it can be determned whether positive conversion of tuberculin reaction is due to natural infection or B.C.G. inoculation (Kosaka, J.A.M.C. No. 375). (c) In six month*s observation of over 1,000 boy soldiers who were inoc- ulated with 8.C.G., it was ascertained that few of the inoculated group fell into tuberculosis, and that with comparatively good progress. (d) B.C.G. is at present Inoculated 0.04 milligram intracutaneously, al- though some recommend that B.C.G. should be inoculated 0,2 milligram sub- cutaneously on the armpit. Those inoculated on the armpit are, however, apt to be affected by by-effects, such as abscess. 2. Tuberculosis Therapy. (a) Cepharantin. Effective to some extent against productive phthisis. Harmful to serious cases (Suzuki, Baba, J.A.M.C. No. 369). (b) Promin. Effective to some extent. Causes haemolytic anaemia as by- effect when given per os, (c) Rhodinlc acid. Ineffective. (d) Spirochaeta morsus muris. Ineffective against phthisis. Its trial use in the therapy of lymphatic tuberculosis, serosa tuberculosis and dis- seminated tuberculosis through circulation is now under consideration. (e) X-ray therapy. Effective to some extent (Yoshlda, J.A.M.C, No, 373). (f) Cavern sucking therapy. Effective to some extent (Makadate, J.A.M.C. No. 365). M-AB RESTRICTED ENCLOSURE (B), continued (g) One-sided artificial pneumothorax in the case of complete adhesion of pleura on the other side may possibly cause serious disturbance in cir- culation (Koizumi, J.A.M.C. No. 373). 3. Malaria Therapy. (a) Plasmodium collecting method and complementary combination reaction, Plasmodiums are collected in the following process: Removal of blood platelets Formaline fixation Removal of leuco- cytes by centrifuge. The complementary combination reaction with the alkaline extract of plas- modium thus collected as antigen is specific not only to malaria, but also to the plasmodlum (Sasaki, Koyama, J.A.M.C. No. 358, 365, 366). (b) "Antimalarien", i.e. 6-methoxy-8-3-diethylamino-2, 2-dimethylpropyl- aminoquinoline hydrochloride, is as effective as plasmochin, but somewhat less toxic than the latter. As more plasmochin was produced and supplied, "Antimalarien" ceased to be used (Sasaki, Koyama, J.A.M.C. No, 334). (c) Of all therapies of malaria heretofore in use, the one with the least recidivatlon rate is a combined usage of quinine, atebrln and "Antimalar- ien". Simple and effective is the way of "a fortnight of quinine and plasmochin" (Sasaki, J.A.M.C. No. 355). 4« Wartime Nutrition Failure. Wartime nutrition failure is the name given to groups of symptoms as a whole, which are basea on malnutrition for a comparatively long period, and qualita- tive hunger, especially of proteins and fats, and in addition complicated by malaria, bacterial dysentery, amoebic dysentery and beri-beri, etc., it has such symptomatical features as emaciation, oedema, anaemia, diarrhoea, polyuria, and slow pulsation, and resists every therapy, making recovery from it all the more difficult. Therapies for the complications are to take vitamin B, liver preparations or raw cow’s liver preparations. 5. Kala-azar. (a) On examining liver function of Kala-azar patients, it was found out that the function of excreting "Azorbin-S" and "Congo red" fluctuates parallel to the sizes of liver and spleen tumors. (Kobayashi, J.A.M.C. No. 369). (b) Antimony preparations were effective on those mice previously treated with alcohol in order to be easily infected by plasmodiums (Furukawa, J. A.M.C. No. 371). 6. Dengue-Fever. (a) Observations on clinical statistics of dengue fever prevalent in Nagasaki in the summer, 1942 (Nagao, Ota, J.A.M.C. No. 359). (b) Transitory plasmachytosis in reconvalescence stadium of dengue fever (Takahashi, J.A.M.C. No, 367). 7. Diseases of Circulatory Organs. (a) Effect of regulation of venous pressure on nerves and hormones (Ta- kahashi, J.A.M.C. No. 367). 122 RESTRICTED M-AB ENCLOSURE (B), continued (b) Irregular pulse with good prognosis (Takahashi, J.A.M.C. No. 354). (c) The so-called aeroneurosis (Osuzu, Toroi, J.A.M.C. No, 362). (d) Obturation of vena cava inf. (Yano, H.A.M.C. No, 362). Note: Reports on the items with no reference have not been published, due to burning of manuscripts and memoranda, etc., making numerical data unavailable. Part Five STUDIES IN THE FIELD OF OTORHINOLOGFY J Research Concerning Prevention of Sea-sickness and Air-sickness by Col. K. Toda (Otorhinolaryngological Department) At present all sorts of medicine are used for means of preventing sea-sickness and air-sickness, but the effect is not only inaccurate, but also the duration time is temporary. Therefore they are just negative measures. The functioning condition of the vestibule and the tension of the vegetative nervous system plays a very important part in developing sea-sick- ness and air-sickness, as is recognized by everyone today. We too, have made investigations on these points and have proved them to be correct. The majority of those who are subject to sea-sickness and air-sick- ness show that they have a very sensitive vestibule and an over-tension vegeta- tive nervous system. While on the other hand, the majority of those having absolute tolerance towards sea-sickness and air-sickness show that they have a low sensitive vestibule and a stable type vegetative nervous system tension. According to this Investigation, to those who are subject to sea- sickness and air-sickness, by lowering the sensitivity of the vestibule by positive means and by stabilizing the tensioning conditions of the vegetative nervous system, we were able to prove experimentally that the tolerance towards sea-sickness and air-sickness could be strengthened by positive means. There- fore there are three ways of lowering the sensitivity of the vestibule and stabilizing the over-tension of the vegetative nervous system. The three ways are as follows: 1. By giving exercises for a limited time and proscribed of rotat- ing movements of the body near the semicircular canal (superior, posterior, lateral) and adding to this the jolting training. 2. Swing movements training for a limited time and presecribed. 3. Radiation of the middle brain (diencephalen) by X-ray. Each one of these three ways will lower the sensitivity of the vestibule and stabilize the tensed conditions of the vegetative nervous system of persons subject to sea-sickness and air-sickness. By it, we were 123 M-AB RESTRICTED ENCLOSURE (B), continued able to prove that they were able to acquire a high tolerance towards sea-sickness and air-sickness. We are confirmed that these were the most logical methods towards the prevention of sea-sickness and air- sickness. Part Six STUDIES IN THE FIELD OF OPHTHALMOLOGY 1. Experimental research on the effect of some vitamins and medicaments on normal light "judgment "In white lower'"lllumination . In order to study the methods of strengthening the light-sense of a man of nor- mal health, the examinations of influence upon normal light judgment under low- er illumination were made with a man of normal health by means of either in- jections or dosing of various medicaments and vitamines, and the result are as follows. The various chemicals and vitamins employed in this experiment do not give any remarkable influence upon the light sense, and slight influence was considered as the effect through the exercise. 2, Manufacture of a simplified quantitative table of examination of color senses. Researches were made with the object of examining easily the degree of abnorm- ality of color sense. The color charts were made in accordance with "Anomalo- skop" while on the other hand, color charts were made with pigment color, whose value is determined to be as similar as possible to spectrum color. These charts were rectified by means of application to the man of unusual color sense, the degree of which was previously determined. 3• Experimental study of the function of accommodation and convergence by side-vision. The researches were made in order to give the optico-physiological rationality to the arrangement of instruments used by aeroplanes, and to contribute to the safety of aeronautics, by eliminating the causes for aeronautical obstacles such as dizziness produced by head movements during action in attitud or ad- vance flying. The results are as follows; The instruments used by aeroplanes are to be arranged within a sphere of vision of aviators extending 30 degrees each right and left, 20 degrees upward and 30 degrees downward with his root of nose in the center, and it is appropriate to Install a concave sphere facing the aviator, those of most importance being placed near as straight forward and horizontal as possible, and these of less importance being by degree placed around the field of fixation. 124 RESTRICTED M-AB ENCLOSURE (B), continued Part Seven DERMATO-UROLOGICAL STUDIES 1. Studies of burn scar. Lt. Col. M. Hiraga. (1) Keloid; We studied the nature of keloid histologically. The over- growth of scar exists in the growth of the connective tissue, whose origin is the endothelial cells in the vessel walls. The degree is individually very different. (2) Treatment: We used radium on the great keloid, and the dose averaged 20 to 50 miligram hours per 1 cm 2. They were all cured in about 3 to 6 months. Other methods of treatment are to cut off the keloid, sew up and afterwards to irradiate with radium or the skin-transplantation (method of Thiersch, Krause or Filatow). We treated about 100 cases of burn scar in this way, and cured almost completely the disfigurement and the dis- turbance of movement. 2, Treatment of trichophytosis, Lt. Col. M. Hiraga. Purpose: We wanted to see the results and mechanism of the various treatments, which have been hitherto used. Method; The majority of the cases were trichophytia interdigitalis, and the local states are wet, crusted, erosive and purulent. The pain and itch are very severe. The medicaments are Tinct, Jod., Kal. permanganicum, Mercuro- chrome, Methylenblue, Thymol, Rivanol, Kal. bichrom., Tar paste, Salicyl alco- hol, Bioform etc. Result; On the wet and erosive surface, we find that one of the most useful methods is the bath with the 5000X-20000X Kal, permangan.-solution. The sur- face becomes dry on the next day. To powder Bioform is also useful. On dried surface we used the following solution, Tinct, jod; 100,0 Thymel 2,0 Methylen- blue 0.5 Acid, salicyl. s*o For the treatment or Trichophytosis the strong oxydating medicaments are most effective. 3. Studies of skin diseases caused by rays. Major I, Yumino. Purpose: The author studied the photosensibilisation and purposed to prevent skin diseases caused by rays. Method; Clinical studies of Porphyria congenita and of eczema solare and ani- mal experiments of photosensibilisation caused by some plants (so-called Fago- pyrism and Atriplicism). Author studied physiologically, chemically and pathologically and especially on the porphyrin circulation, but is very influenced by liver function. The nature of Porphyria congenita and of Hydroa vacciniforme is different and they are other diseases. In the body of the patient of Porphyria congenita, were great deal of uropor- phyrin I, which is the cause of photosensibilisation, but other causes must be looked for. 125 M-AB RESTRICTED ENCLOSURE (B), continued In eczema there was found not only the excretion of porphyrin, but also the disturbance of liver function, and the latter is more important. In the photosensibilisation, the rays of green and yellow are stronger than the ultraviolet rays. The fagopyrism is seen most severely in guinea pig but and in rabbit and mouse is not so clear. The so-called atriplicism is not so distinct in animals. 4. Studies of dermatological medicine as fit for the pending emergency status. Lt. Col. M. Hiraga. The purpose is to find good substitutes for ointments, zinc oxide and medica- ments against scabies and so forth. Results: (1) Substitutes for zinc oxide: Silica and Bentnite are useful. In some cases, we see irritability, but generally they are useful. (2) "Cetanol" ointment; This is made from whale wax and is fit for the basal ointment. (3) Medicaments against scabies: As the substitute for Mitigal Bayer (Scabol) we used flowers of sulphur, Unohana and Kalium sulphide as oint- ment, Liniment and solution. These are effective. (4) Tar-paste: We used the mixture of the tar, which is made from pine- root-oil, and silica or Wilson Paste. (5) "Chlsoko": We used "Shikon" as a substitute for mercurochrome mixed with honey wax and zinc oxide. This is effective on the purulent, crust- ed and erosive surface. 5. Studies of stones in the urine passage originating from wounds. Lt. Col. M. Hiraga. (1) Statistical observation: An account of the sorts of injuries of 114 battle injured patients, who had stones in their urine passage, is as follows: Injury of spinal cord 40.3$ Injury of uric organ 23.7% Fracture of pelvic bone 17.5% Fracture of inferior extermity ... 16.6% The urinary stone were found among 43.5% of the spinal cord injured pati- ents who lived, and by antopsy 72.1% were found. Among the 510 patients, who were injured on the upper half of the body, only one patient had a urinary stone. (2) Cause: The uric dam, disturbance of urination and uric infection are the more important causes of formation of stones that Ca-or vitamin circulation. (3) Components of stones; By chemical analysis the elements of stones are as follows: 126 RESTRICTED M-AB ENCLOSURE (B), continued Phosphate 1+6,6% Carbonate 26,6% Urate 6,6% Oxalate 8,9% Xanthln 1.1% (4) Prophylaxis: To avoid uric dam, disturbance of urination and uric infection, the patients must move their body as early as possible, drink much water and take disinfecting medicaments. 6. Studies of wound in urogenital apparatus. Lt. Col. Mv Hiraga. (1) Treatment of rupture of the bladder. \ Purpose: In animal (dog) experiments, in the cases of intra- and extra- peritoneal bladder injuries, we observed the time which is enough to save by operation, and the cause of death. Results; The cases of the intraperitoneal rupture of the bladder is to be secured witnln 12 hours after injury. Some of the intraperitoneal rupture of the bladder died with 20 hours, and we investigate now chemi- cally and bacteriologlcally the cause of their death, (2) Plastic operation. (i) In all the cases of posterior urethra injuries, we use the end- less catheter and they are very effective, (ii) Artificial penis plastic: In 6 patients who lost their penis, we made artificial penis with Bogoras* method. In the five cases, we used the Pilatow-flap of the abdominal skin, and in one case used the skin of the thigh and sartorius, thereby we used the fascia for urethra, but the latter method is not so good, (iii) the injuries of the bladder and urethra, we found that the continued use of the suprapelvic catheter is harmless and effective. , Part Eight STUDIES IN ORAL SURGERY 1• Studies on the jaw-splint used in the battlefield. Various kinds of splints for fixation of the fractured mandible have been in the beginning of Manchurian Affair and .Sino-Japanese Conflict, but since 1937 we have chiefly used a kind of special hooked splint, the so-called "Jaw-splint used in the battlefield", for this purpose. Since the splint is made of nickel-chrome alloy, we have been looking for some other metals for the reasons of shortcoming of the material and its character which is easily hardened by cold-working. After -various experiments, special alloy was made which chiefly consisted of silver, containing S% copper and some other elements. By this newly made alloy, we could almost accomplish our purpose to fix the fractured bone rigidly and the hardness of this metal {Brinell ca. 40) was re- 127 M-AB RESTRICTED ENCLOSURE (B), continued covered (Brlnell 70-80) by heat treatment between 6000-700° C, after bended easily to the form of dental arches, Tfie study to simplify the production of the splints by way of modifying the fibrin of the splint was forced to discontinue due to the termination of war. 12, Studies on the homoplastic transplantation of bone in mandible. For the purpose of studying whether the homoplastic transplantation is practi- cally possible or not and whether the periosteum (macrosconically) is indispen- sable or not for this purpose, experimental operations were carried on in 11 cases with defects on the mandible due to gunshot wound. There being two cases being operated on at the same time, we divided the bone from the tibia which is to be transplanted into two halves, and one half was transplanted in the same individual and the other half to the other. Of course the transplanted bones were divided into two groups, the one with periosteum, the oth> r without periosteum. The results are as follows; Operations Number Intention Resorptj on Suppuration Periosteum With 5 k 3 1 Without 6 6 0 0 Conclusions from these experiments are as follows: (1) Homoplastic transplatation of bone in mandible is possible, result- ing in 10 out of 11 cases perfectly united with bone, (2) Bone without periosteum also were united with bone perfectly without / any disagreeable (Sic). p. Studies on the transplantation of preserved bone In mandible. Experiments on the transplantation of preserved bone were carried on in 10 cases with mandibular fracture, the defects measuring from 0.5 to 2,0 cm. The bones used for this purpose were taken from the tibia of different individuals and most of them were preserved in physiological saline solution or in Ringer's solution for a few days. If it is necessary to keep specimens longer than 12 hours, it is recommended to keep them in Ringer's solution at 2°C - 3°C. The results of this experiment on 10 cases show clinically and roentgenologic- ally quite perfect unity of the transplanted bone with the healthy one, though the observation period differed from 7 months to 12 months. In order to make more exact observation, a longer period of observation is re- quired, but from these experiments we can positively say that bone preserved for a week is available for the transplantation. 128 RESTRICTED M-AB ENCLOSURE (B), continued Part Nine STUDIES IN THE FIELD OF SURGERY 1. Injury on head. In accordance with the late progress of neurosurgery, the more active, opera- tive treatment is adopted for battle injuries to the head. Pneumoencephalo- graphy and arteriography is very highly valued as the method of examination. (1) Foreign body (mainly bullet and fragment) in the brain {1) (2). If possible, extraction is tried in all cases, to prevent the development of abscess as well as epilepsia afterwards and to remove the nervous un- rest of the patient. The wound in the soft part is to be healed, before extraction is planned. Extraction usually is by means of osteoplastic craniotomy. Not seldom we succeed in fishing the foreign body from the small orifice in the skull (3). No accident during the operation and un- eventful aftercourse. (2) Traumatic epilepsia (4). With the conception that traumatic epilepsia is caused by traction of the scar upon the brain tissue, we try to resect the damaged, unhealthy part of brain or meningeum as wide and deep as possible, until the brain cham- ber in few cases. On the defect of meningeum, fascia is transplanted. About half of the operated cases shows improvement or healing. (3) Brain abscess (5) (6). In those patients who got injuries on head, the development of brain ab- scess is frequently fatal, especially when it perforates into the chamber. Varous kinds of study are done on the initial symptoms and X-ray pictures of brain abscess, for the purpose of knowing the development and localis- ation. It is often true that the foreign body in the brain stimulates latent brain abscesses, whose diagnosis is not easy. 2. Injury on chest. (1) Projectile in the lung (7) (8). About five hundred cases were treated in our clinic. Our principle of operation for the extraction of a projectile is as follows. (i) Cases in whose pleura no adhesion exists (including adhesion in little grade) . Preliminary artificial pneumothorax is necessary, two or three times, with the interval of three or four days, and the amount of air is from 800 cc to 1500 cc. The pleural cavity is to open without any arrangement of pressure control usually the lung is collapsed already so well, that the respiration is not disturbed remarkably. As the operator could grasp the lung in the pleural cavity with his own hand, inserted from the incision wound, the extraction of projectile is not so difficult, except in the lung hilus. 129 M-AB RESTRICTED ENCLOSURE (B), continued (ii) Cases, in whose pleura marked adhesion exists. Preliminary artifical pneumothorax is useless. An operation-table with X-ray apparatus is very helpful. After the surface of the lung appears in the operation, we probe the projectile with the needle under the fluoroscopic control. If the needle catches the object, the lung tissue is dissected with the electric knife. The influence of the operation upon temperature, pulse and respira- tion disappears within one week and the reduced vital capacity re- covers in the course of several weeks. (2) Empyema after chest injury (9) (10) (11). Causes Per cent Unproper site of drainage 19% Wrong method of drainage 22% Bronchial fistual 14% Foreign body 52% Mixed infection of tuberculous bacillus 44% Foreign bodies found are generally: The rubber tube for drainage, a frag- ment of the projectile, bone, gauze or piece of cloth. These oases, how- ever, take an uneventful course after the extraction of the foreign body. For the diagnosis of mixed infection an examination, clinical as well as bacteriological, is to be carried out. We must confess that an average of six microscopic examinations was re- quired to find the T.B. bacillus for the first time and the inoculation test was necessary in 65% of all cases. The cavity of T.B. empyema is known to locate posteriorly near the spinal column, reach to the first rib and to contain the bronchial fistual in 40% of the cases. Treatment is not easy but we get good results by extrapleural thoracoplasty. The operation is divided into two or three stages, according to the phys- ical condition of the patient. Caution must be paid to keep the operat- ing field sterile, protecting it from the discharging wound. About 50% healing of one hundred operated cases. 3. Injury of blood vessel - aneurysm -(12) (13). The main points of many valuable studies about aneurysm in our clinic will be abridged here. (1) Method of operation. As the natural healing of aneurysm is not to be expected, operation is to be recommended. Though the ligation of blood vessel with the complete exstirpation of the sac is estimated as a good method, the arteriography after exstirpation of the sac, if possible, is concluded by us to be bet- ter, Even when we are obliged to leave the sac behind, the inside of the sac is to be opened and obliterated. The ligation of the vessel alone is not proper, causing the reappearance of aneurysm. (2) X-ray examination. For diagnosis of aneurysm, the x-ray examination especially arteriography, 130 RESTRICTED M-AB ENCLOSURE (B), continued is very important, by means of which the sort, site, size and from of aneurysm, the anatomical relationship between the sac and the blood ves- sel, the damage of the blood vessel condition inside the sac, and the de- velopment of the coagulated mass as well as the collateral vessel are clarified. (3) Pathologic anatomical finding (14). All cases were proved to be false aneurysm. On the damaged part of the vessel, the thickening of the vessel wall, most markedly of adventitia, next intinia. The wall of the sac consists of the fibrous tissue. 4. Peripheral nerve lesion (15). About four thousand cases of peripheral nerve lesion have been treated. Lesion of sciatic nerve is most frequent (45%) lesion of the median nerve, ulnar nerves, and combined lesion of the median and ulnar nerves occurred, in this order of frequency. Upon operation we find complete defect of nerve tissue in 25%, partial defect in 15%, formation of scar tissue (neuroma) in 14% and ad- hesion with adjacent tissue in 46%. The results of operations follow; Method of operation Number of cases Healing Improvement Unchanged Neurolysis Excision of scar- 664 54.8% 29.5% 15.7% tissue neurography 277 60.3% 27.1% 12.6% Nerve graft 152 41.4% 40.8% 17.8% The shorter the time from injury to operation, the better the result of the operation, —83% healing if operated on within two months as against 44% heal- ing if operated on after six months. The fat is most suitable for the protection of the lesion part, though we should avoid the use of a foreign body, if possible. For paralysis of the peripheral nerve many kinds of orthopedic operation as well as the application of prosthesis are done. 5. Injury of extremity (16) (17) (18) (19) {l} Nonunion and jnalunion of long bone: About three hundred cases have been treated. The main causes of these cases are early removal of bone fragments, bad fixation severe infection, imperfect reposition, large defects in soft tissue, etc. For treatment bone grafting is considered to be best. Until the operation three or four months should be waited after the wound begins to heal completely, A bed for the graft bone is built between the upper and lower fragment at first. No sign of infection is permitted for the graft operation. The one graft is cut out of the Croat of tibia and held in place with silver wire, which is to be tried one week later after the preliminary operation. Perfect fixation of the operated on extremity should be con- tinued for three months. Good results in 89.8%. 131 M-AB RESTRICTED ENCLOSURE (BJ, continued (2) Deformity after fracture: About one thousand and three hundred cases have been treated. For treat- ment, traction with Kirshner’s wire is continued after the oblique osteo- tomy in or off the callus. We succeed in lengthening five or six cm. on the average and in correcting the bending of the bone. In some cases a bone splint from the tibia crest is applied. Caution for the resting in- fection cannot be paid too much. *6, Artificial limb and prosthesis. (1) Artificial limb for the upper extremity: Some modification is added to Brandenburgs' prosthesis as the working arm. An elbow joint is used which is a universal spherical joint which can be locked at any direction. The weight is 1710-1730 gr. for the upper arm amputated and 920-1250 gr. for the forearm amputated. At the ending, var- ious kinds of app]icances for the artificial hand are connected, of which a "C"-hook, four cm. in diameter with an opening of three cm. arc-length, is most useful. The ornamental cover is usually furnished. Sauerbruch’s hand and Kruchenberg's operation is out of usage. (2) Artificial limb for the lower extremity: Every amputates practises the training to walk with the provisional pro- sthesis for three months before he uses the permanent prosthesis. The permanent prosthesis has a butterfly joint and patella as a substitute for knee joint, but lacks the ankle joint. It looks just like the healthy leg and can be flexed as much as 90 degrees in the sitting position, but cannot help tottering during walking. The socket is made of aluminium. Only the artificial limb of standard type is delivered to the amputated in the army, while many kinds of prosthesis are manufactured in accordance with his profession by the welfare ministry, (3) Prosthesis: In paralysis of peripheral nerve s.p. fibular nerve and radial nerve suit- able prosthesis is applied to hold the* dorsiflexion of the wrist and right angle position of the ankle. For the shortened leg a prosthesis like Grossmith's is used, to compensate for the lost length. Bibliography (including the principal literature only) (1)(7) K. Ibuka Nippon Gekagakkai Zasshi - Vol. 42, No. 7 - 1941 S. Idezuki (Journal of the Japanese surgical association) (2) H. Shimada in printing (3) M. Fukuda personal communication (4) N. Aizawa in printing (5) H. Yoshloka Gunldan Zasshi (Journal of the Military Surgeon) 1939 (6) N. Aizawa Gunidan Zasshi - 1942 (8) K. Tamamura Gunidan Zasshi - No. 339 (9) G. Achiwa Gunldan Zasshi - 1941 132 RESTRICTED M-AB ENCLOSURE (B), continued (10) D. Nagae Nippon Gekagakkal Zasshl - Vol. 43, No. 9 - 1942 (11) T. Nakamura Gunidan Zasshi - No. 322 (12) K. Hosomi Nippon Gekagakkal Zasshl - Vol. 41, No. 7 - 1940 (13) M. Fukuda Gunidan Zasshl - No. 330-333 (14) M. Fukuda Gunidan Zasshl - No. 338-379 (15) A, Nakamura Nippon Gekagakkal Zasshi - Vol. 43, No. 9 - 1942 (16) K. Haniude Nippon Selkeigekagakkal Zasshi - No. 4 K. Takigawa (Journal of the Japanese orthopedic association) (17) S, Tokuoka Nippon Seikelgekagakkai Zasshl - 1943 (18) H. Kinoshita Nippon Selkeigekagakkal Zasshi -in printing (19) T. Nishiwaki Gunidan Zasshi - No. 374 Part Ten STUDIES IN THE FIELD OF PSYCHIATRY Summaries of Psychoneurological Treatises Konodai Army Hospital 1. Manifestation and Development of Aspect of War Neurosis, 2. Psychiatric Observations on War Neurosis. 3. On Psychiatric Judgment of Punished Soldiers. 4. On Psychiatric Judgment of Criminal Soldiers, Expeslally Viewed from Med- ical Standpoint for Prevention of Crime. 5. Investigation on Soldiers of Psychiatrically jLow Disposition. 6. Therapy of Schizophrenia. Manifestations and Development of Aspects of War Neurosis (J.A.M.C, Special number 2-3 l Lieut. Akira Kasamatsu War neurosis cannot, when regarded as a psychogenetic reaction, be treat- ed with a conception that it forms a unit of diseases in medical -science, as is the case with many other functional diseases. It should be diagnosed from all the aspects it shows, which are separated from each other by analyzing the composition formed by them. The author had made investigations on this subject from the following two viewpoints. The first is the question of what change may be brought forth on the aspect of disease by change of environment, such as front line and rear zone, or entry to hospital-army hospital abroad-returning voyage-army hospital at home-depar- ture from hospital. In the light of this viewpoint, there are more symptoms chiefly of psychiatric nature, such as the reaction of fright, in forward zones, and more hysterized physical symptoms in the rear. War neurosis exhibits an uninterrupted transition of aspects of the disease. For example, the nearer to the front, the more obvious the reflex self-defen- sive instinct, and the nearer to the rear, the greater the so-called tendency of wish. 133 M-AB RESTRICTED ENCLOSURE (B), conllnued The second is the question of how the elements, war and race, are pathoplasti- cally shown on the aspects of disease. (1) Contrary to expectation, there are not many cases in wartime where neurosis is diagnosed as neurasthenia, in comparison with peace, (2) Few patients show reactions akin to that of fright. Many cases ex- hibit reactions of inner conflict, (3) There are many cases showing more or less disturbance of conscious- ness at first. (4) Even those symptoms to be regarded as Ganser's dazed condition are more of a stimulating, agonizing and depressive nature than comic and Jesting. (5) The symptoms display the following mode of development: Feeling of responsibility - Depression - Disturbance of consciousness - wish of death It presumbaly denotes the racial characteristics that there are many cases where tendency of wish as the basis for the development is not recognized, (6) Such physical symptoms as paralysis of power of locomotion and tremor, etc., coming promptly after being frightened, are few. (7) Hysteric symptoms are much affected by the special circumstance of being transported over the sea by hospital ship. After all, war offers opportunities to examine the strong and weak points of races. Psychiatric Observations on War Neurosis. ■*( J.A.M.C. No. 243 - 245, 249 - 251) Lieut. Tsunao Sakural The so-called war neurosis first named and described at the time of World War I involves too many aspects to come under the same category with what the author has had as the object. The author has tried to make sharp the focus of the problem with particular emphasis laid on the fact that war neurosis is a type of psychogenetlc reaction. War neurosis is characteristic in the fact that besides obviously neurotic pat- ients there is a group of many patients who have a latent tendency toward neu- rosis. It is pointed out that here lies the complication and the vastness of this problem. This disease is brought forth chiefly by the interaction of the patientfs bad disposition due to his character and circumstantial and external factors. It was clarified that the three important factors, preparedness, impulse and spec- ial self-experience, take part in provocation of the disease, which is second- arily aggravated by appearance of a utilitarian sense. The author assumed a stratified composition of character to locate the group of the ideas forming causes of diseases in these character strata. He has tried to explain clarity of consciousness and purposefulness in symptoms with the foregoing assumption, and to find a law on the aspects covering from pure neurosis to simulation and transition into each other of these symptoms. In conformity with this idea, the author classified war neurosis into five forms, hypochondric form, paranoid form, utilitarian form, bright form and escape form. He believes that this classification is not only scientifically interesting, but practically useful for deciding treatment and anticipating prognosis of each symptom. 134 RESTRICTED M-AB ENCLOSURE (B), continued The secret of this therapy is first, to detect psychical causes and to remove them. Second, in case these causes cannot be removed, to smash feelings of wishes or expectations accompanying them and rectify patient’s psychical atti- tude. To realize this, such measures as persuasion, suggestion and compulsion should be taken as demanded by each case. However, the author has applied the newly established convulsive treatment of electrification to neurosis .with distinguished result and has recommended widespread use of it in the descript- ion of its application and mechanism of effectuality. It has been generally believed that Naegeli's so-called "Kapitalabfindung" (Capital paying off) meth- od is the only therapy for traumatic neurosis, but it was impossible to intro- duce it into army therapeutical system without changing its form due to var- ious circumstances. A substitute method had been badly needed, until the auth- or and his co-workers took up a new method based on this convulsive treatment of electrification, breaking down to the field of therapy of neurosis. On Psychiatric Judgment of Punished Soldiers (Accompanied by Psychiatric Investigation of Soldiers under Surveillance) Lieut. Tadashl Tanaka and his two co-workers According to the authors investigation made on 11 regiments belonging to the Eastern Army (Soldiers investigated totaled 11,656), 83 punished soldiers were found, amounting to a percentage rate of 0.71%. From them, those who were supposed to be psychiatrically normal, having been punished on account of their subordinates’ misconducts or automobile accidents, totaling 20, are excluded. The remaining 63 comprise 42 normal soldiers and 21 abnormal, the latter being one third of all the punished. The 21 abnormal comprise the following cases; Imbecility 5 Debility 3 Weakness of intellect Anomaly of character 9 Otherwise 4 On inspection of 31 soldiers, unpunished but under constant surveillance, there were only two normal soldiers and the remaining 29 abnormal comprised: imbecility 15 Debility 3 Weakness of intellect Anomaly of character 2 Schizophrenia 5 Maniac-depressive psychosis 2 Epilepsy 1 Postmeningitic state 1 From both investigations it is summarised that at least 50 psychiatrically ab- normal soldiers served in the 11 regiments of the Eastern army, and they were apt to commit crimes and constitute a great hindrance to education and train- ing. The author advocates that the first importance should be given to examining soldiers1 mental health to ensure early discovery of abnormalities and the tak- 135 M-AB RESTRICTED ing of measures to cope with them in order to prevent crimes and maintain dis- cipline. ENCLOSURE (B), continued On Psychiatric Judgment of Criminal Soldiers, Especially Viewed from Medical Standpoint for Prevention of Crime. Lieut. Tadashi Tanaka The following results and suggestions were obtained from an investigation from various points of view of forty criminals who had been put to psychiatric judgment at Konodai Army Hospital. (1) The crimes cover nearly all categories of crimes, of which desertion from barracks is most remarkable in number. Most of the deserters are second privates. (2) Of the 40 cases, 38 (95%) were mentally abnormal. This shows that crime and misconduct are in close connection with mental abnormality. Hence extremely speaking, it is desirable that all criminals should under- go psychiartic judgment, (3) Two soldiers of the normal group are new recruits who had not been loved in their own homes. This should be kept in mind by those who occupy leading positions, (4) The 38 mental abnormalities are classified, according to kind of disease, as follows: Schizophrenia 14 (36.9%) Psychopathia 8 (21.1%) Hysteria 6 (15.8%) Weakness of intellect 5 (13,2%) Paranoia 1 ( 2.6%) Progressive paralysis 1 ( 2.6%) Malaria 1 ( 2.6%) Psychiatric disturbance 1 ( 2.6%) Pathological drunkeness 1 ( 2,6%) Depressive reaction 1 ( 2.6%) (5) In the classification according to rank and kind of disease, antici- pated results were obtained in general, except one officer was hysteric and all cases of non-commisioned officers, four in all, were psychopathic. (6) According to the classification from the viewpoint of kind of crime and kind of disease, profound crimes, such as lese majesty, disobedience killing or wounding a superior and murder; were commited exclusively by psychosis in a narrow sense, comprising for the most part schizophrenic crimes of weakness of intellect and hysteria. While crimes of psychopaths ia include considerably malignant ones, such as intimidating a superior, arson, etc. (7) The psychiatric symptoms which constituted the direct causes for commitment of crimes are divided into the following; Clouding of consciousness 9 cases Delusion 9 cases Weakness of Intellect and dementia 10 cases Depressive feeling 1 case Self-indulgence, indignation 6 cases diseased desire etc. Fitful impulse 3 cases 136 RESTRICTED M-AB ENCLOSURE (B), continued All the crimes committed by the above-mentioned psychoses were brought about by various delusions. (8) The period from the begining of the disease to commitment is, apart from 13 oases of weakness of intellect and psychopathia, over several months in 14 cases of other kinds of mental disorder, numbering 25. Dur- ing this period most of the criminals were suspected of their abnormality by the people surrounding them, who, notwithstanding, did nothing with them, because of their poor knowledge of psychiatry. (9) Of the 38 cases, 14 cases are ex-convicts. Even the sinless group involves over seven cases of misconduct of such kinds as getaway or the breaking of furniture. From this, also, it is obvious that the psychia- trically abnormal tend much to frequent offence, (10) Except one each case of malaria, psychiatric disturbance and depres- sive reaction, all cases were so aggravated that exemption from military service was necessary. (11) Psychiatric Judgment would be almost of no value, if it is used only for reference in deciding whether Article 39 of the Criminal Law should be applied. It is obvious as afore-mentioned that criminals of psychia- tric disturbance would most probably take to further offence, no matter whether they be punished or not, if they are freed into the world at large. Accordingly, psychiatric judgment would be practical, if it is used in this way. First, if it tells exactly what the disease is and points the way to the future of the disease. Then, medical treatment should be given to those needing it. Isolation from the world should be forced upon those who ought to receive it and maintained until there is no fear of offence (even life time Isolation for those whose offence is probable all their lives!). If necessary, vocations appropriate to each case should be taught to patients who are to be at large, lest they live in idleness. Only 40 cases of psychiatric Judgment are referred to here, and presumably there are many mental abnormalities with crimes not undergoing psychiatric Judgment as yet. Measures to cope with this should never be neglected. Investigation on Soldiers of Psychatric Low Disposition Konodai Army Hospital As the war dragged on and expanded with the upward trend of mobilization rate, soldiers of psychiatric low disposition increased in number, as physic- ally weak soldiers did, constituting grave causes of crimes and misconducts and lowering the efficiency of education. In accordance with this situation, we have made several investigations of men of psychiatric low disposition in the army to offer help in the prevention of crime and misconduct and in the promotion of the efficiency of education. The results of the Investigations are summarized in the annexed lists No. 1 (Distribution of Men of Psychiatric Low Dispostion) and No. 2 (Distribution of Men of Low Intellect). As shown in them, of those found to be psychiatrically low disposed, the worst cases were sent to the hospital and advice on educat- ion and training for slight cases was given to those in charge of them. 137 M-AB RESTRICTED ENCLOSURE (B), continued Individual inspection Result of individual inspection Treatment Category of troop Tear Total of the inspect- ed Person- nel in- spected Method of se- lection Weakness of intellect Psycho- pathic Other Psycho- neurosis No re- markable findings Hospital Protection Artillery 1941 1943 total 1,067 676 1,703 25 32 77 (4.511) Mental health test Mental test 13 43 38 (3.40%) 4 4 8 8 7 7 7 6 (0.74%) 18 39 (3.34%) Army Hospital 1941 1942 1943 1944 96 360 156 875 10 24 14 87 Mental test and Mental health test 8 20 14 84 1 1 1 1 2 3 4 3 6 18 14 78 total 1,487 135 (9.07 %) 126 (8.4.7%) 3 5 3 d.o2n) 116 (7.80%) Air Defense Corps 29,16 28l (0.96%) Mental health test (0.93%) 7 53 4 (0.62%) 96 (0.33%) Technical Corps (tank, engineer, artillery, communica- tion etc.) 1944 1,697 100 Mental test and Mental health test 73 2 1 22 13 63 Medical privates’ training Corps 1944 total 323 2,020 17 117 (5.80%) 13 9° (4.50%) 2 1 2 1 23 2 13 (0.75*) 14 (,!&) Infantry, Cavalry, artil- lery Engineer (Reservist Militia) 1944 7,089 419 (3-91%) Mental test and Mental health test 217 (3.82%) 17 17 114 32 (0.45%) (3^85%) 2 troops in a certain divisional district 1945 12,691 190 (1.49%) Mental health test 141 22 23 4 79 (0.62%) 107 Total 34,157 1,219 901 53 108 133 336 (0.12%) 728 Distribution of Men of Low Disposition (Result of Individual Inspection) 138 RESTRICTED M-AB ENCLOSURE (B), continued Distribution of Men of Low Intellect Category of Personae! Investigator Investigated personnel Inbeoluty (%) Debility (1) Total of the weakly Intellectod 2 \ Lieut. Colonel V [} Major xi\ >2 V i 'n f 1( phar- macist in ad- V2 ditional post) J Captain > fX. \ piiCLL— j macist) / J >2 Lieutenant r 2 > 2(phar- macists ) Second Lieut. J J A. Non-commissioned medical officers 5 7 4 2 Medical men 3 3 2 Orderly men in duty for officers 3 4 2 Men in duty for horses • 2 Total 16 20 14 5 Kin addi- tional post) Riding horses 2 1 Equipment of the Army Medical Department-Office Medical Stores: Medical trunks for the unit Officer’s carrying bag the sane as the officers number Bags for treatment the same as the non-commissioned officers number Bags of bandages the same as the medical men one net 152 RESTRICTED M-AB ENCLOSURE (C), continued Table of Organization of the Array Hospital (Inland) The first class The second class Tiie third class A B 1.1 aj. General l(the chief) Colonel 1 l(the chief) Lieut. Colonel 1 \ >1( the j chief) Major 2 Captain 8 }2 l(the chief) Second Lieutenant 16 8 1 Lieut. Colonel or Wa j or(pharmac is t) 1 Captain!pharmacist) 2 1* Second Lieutenant {pharmacist) 4 % 1 Medical officer (not specialist) 3 2 1 Non-commissioned medical officer 52 26 3 2 Non-commissioned technical officer 3 2 Medical man 290 150 30 2 Intendant officer 4 2 Non-commissioned intendant officer 6 4 2 1 Total 394 204 40 17 153 M-AB RESTRICTED ENCLOSURE (C), continued Table of Organization of the Section of the Ambulance Corps Captain l(the leader) Sergeant-major (Sergeant, corporal) l(the secretary) (Medical) Captain 2 (Medical) Lieutenant or Second Lieut, 4 Non-commissioned medical officer 9 Medical men 36 Non-commissioned intendant officer 1 Total $4 Equipment of the Section of the Ambulance Corps 1. Medical stores: Amounts Medical trunks for the unit 6 sets Stretchers 240 Officer’s carrying bag 6 Bag for treatment 9 Bag of bandages 36 2. Others: Utensils Table of Organization of the Headquarters of the Commissariat Ambulance Corps Colonel or Lieut, Col. (Medical) l(the chief) Major (Medical) 1 Captain, Lieutenant and Second Lieut. (Medical) 1 Sergeant-major, Sergeant or Corporal l(the driver) Men 8 Non-commissioned medical officers 3 Medical men 10 Intendant officer 1 Non-commissioned intendant officer 1 Total 2? ! 154 RESTRICTED M-AB ENCLOSURE (C). continued Equipment of the Headquarters of the Commissariat Ambulance Corps 1. Medical stores Medical trunks for the unit 1 set Officer’s carrying bags 3 Bag for treatment 1 Bags of bandages 2 2. Cars Riding cars 2 Trucks 1 Table of Organization of the Commissariat Hospital Lieut. Colonel or Major (Medical) 1 (with a horse) Captains (Medical) 5 Lieutenants and Second Lieut's (Medical) 25 Captains, Lieutenants, or Second Lieut’s (Pharmacist) 2 Captains, Lieutenants, or Second Lieut’s (not specialist) 2 1 (engaged in Non-commissioned medical officers 67 supply) Non-commissioned technical officers 2 Medical officers 250 Intendant officer 1 Non-commissioned intendant officers 2 Men in duty for horses 1 Total 359 persons and one horse Equipment of the Commissariat Hospital 1. Medical stores Medical trunks for hospital use 4 sets Sterilizer with operation-lamp for field use 8 sets Operation-bed for field use 4 sets Miscroscope and its case 2 sets Stretchers 20 sets Water-Supplier (B) 2 sets X-ray apparatus for field use 1 set Officer’s carrying bags 31 Bags for treatment 14 Bags of bandages 50 Dental trunks 1 set 2. Others Utensils, Patient-clothes, etc. 155 M-AB RESTRICTED ENCLOSURE (CJ, continued Table of Organization of the Divisional Water-Supplying Corps Lieut. Colonel or Major (Medical) Captains, Lieutenants and Second Lieut's (Medical) Captain (pharmacist) Medical officers (not specialist) Special medical sergeant-major Non-commissioned medical officers Non-commissioned technical officer Medical men 1 6 1 2 1 20 1 90 Total 112 Special sergeant-major (of Army Service Corps; 1 Non-commissioned officers (of Army Service Corps) 4 Men (of Army Service Corps) 108 Intendant officer 1 Non-commissioned intendant officer 1 Non-commissioned technical officer in mechanical engineering 1 Non-commissioned technical officer in electrical engineering 1 Total 117 Sum, total 239 Equipment of the Divisional Water-Supplying Corps 1. Medical trunks for the unit 1 set Trunks for the Water-Supplying Corps 1 set Officer's carrying bags 7 Bags for treatment 4 Bags of bandages 10 2. Cars Riding cars 1 Trucks 28 Water-supplying Cars (A) a 156 RESTRICTED M-AB ENCLOSURE (C), continued Table of Organization of the Army Water-Supplying Corps Lieut, Colonel (Medical) Major (Medical) Captains (Medical) Lieutenants and Second Lieut*s (both Medical) Pharmacist Officers Medical officers (not specialist) Special medical sergeant-major Non-commissioned Technical officers Medical men 1 1 2 10 2 2 1 2 150 Total 205 Special sergeant-major 1 Non-commissioned officers 4 Men 114 Intendant officers 1 Non-commissioned intendant officers 2 Non-commissioned technical officer in electrical engineering 1 Technical expert 1 Non-commissioned technical officer in mechanical engineering 1 Assistant experts 3 Total 128 Sum total 333 157 M-AB RESTRICTED ENCLOSURE (C), continued Equipment of the Army Water-Supplying Corps 1. Medical Stores Medical trunks for the unit 1 set Trunks for the Water-Supplying Corps 1 set Appending trunks for the Water-Supplying Corps 1 set Trunks for physico-chemical use 1 set Officer’s carrying bags 14 Bags for treatment 7 Bags of bandages 1$ 2. Cars Riding cars 5 Trucks 34 Water-supplying cars (A) 6 Table of Organization of the Circulating Infirmary of the Commissariat Ambulance Corps Major (Medical) 1 (the chief) Captains (Medical) 2 Lieutenants and Second Lieut’s (Medical) 6 Captain, Lieutenant or Second Lieut. (Medical) 1 Non-commissioned medical officers 8 Non-commissioned technical officer 1 Medical men 50 Sergeant-major, Sergeant or Corporal 1 Men 23 Total 93 Equipment of the Circulating Infirmary of the Commissariat Ambulance Corps 1. Medical stores Motor-car for treatment 1 set Motor-car for removing poisonous gas 1 set Officer’s carrying bag 9 Bags for treatment 2 Bags of bandages 10 2. Cars Riding cars 1 Trucks 4 158 RESTRICTED M-AB ENCLOSURE (C). continued Table of Organization of the Medical Section of a Hospital-Ship A. Organization Major (Medical) * 1 Captains, Lieutenants and Second Lieut's (Medical) 6 Captain, Lieutenant (Pharmacist) 1 Non-commissioned medical officers 13 Non-commissioned technical officer 1 Medical men (superior privates) 20 Medical men 60 Total 104 ♦ The Senior Officer B. Organization Major (Medical) * 1 Captains, Lieutenants and Second Lieut’s (Medical) 3 Captain, Lieutenant (Pharmcaist) 1 Non-commissioned medical officers 9 Non-commissioned technical officer 1 Medical men (superior privates) 12 Medical men 34 Total 61 * The Senior Officer Equipment of the Medical Section of a Hospital-Ship (for A, and B Organization) 1. Medical stores Amount Medical trunks for the unit 1 set Trunks for physico-chenlcal use 1 set Medical trunks for the hospital-ship 1 set Sterilizer with operation-lamp for field 1 set use 1 set Microscope and its case 1 set Officer’s carrying bag some Bag for treatment some Bag for bandages some 2. Others Patient-clothes some 159 M-AB RESTRICTED ENCLOSURE (C), continued Table of organization of the Ambulance Corps of the Front Line Headquarters Company Cart Company Stretcher Company 05 a o 05 a © 05 © 05 a o 9S to a o 2S 05 © a a o a o N 0) P4 •n u as © o O XI *4 © P4 KS U as *4 © 04 •b *4 as f4 U © O O X3 u © P* >4 S Lieut. Col. or Major l(the head) i 1 1 Captains Lieutenants or Second Lieut's Special sergeant-majors l(the adjutant) 2(the secretary) i l(the leader) 2 1 3 l(the leader) 3 i 3 17 8 Sergeant-majors 1 1 38 Sergeants (corporals) Men (superior privates) Men 2(engaged in supply) 10 8 12 162 6 17 549 Men (of Army Service Corps) 46 56 246 36 Total 16 2 187 1 74 4 36 851 45 NCO (of Army Service Corps) 3 3 3 3 Men (of Army Service Corps) 96 6 70 96 76 Intendant officers 2 2 NC intendant officers 2 NCO in sewing-work 1 1 NCO in installation-work 1 1 Major (Medical) Captain (Medical) Lieutenants or Second Lieut's (Med.) l(the chief med- . ioaJ officer) 5 3(engaged in £ removing gas) 1 6 1 14 1 6 Officer (Pharmacist) 3 3 NC medical officer Medical men 22 6(engaged in g£ removing gas) 28 88 Veterinary officers 1 1 1 NC veterinary officer 1 1 1 Men in duty for horses 10 1 4 17 Total 249 17 70 1 4 258 87 Sum total 265 19 70 188 1 78 4 36 1,109 132 Equipment or the Ambulance Corps of the Front Line 1. Medical stores Amount Medical trunks for the Ambulance Corps 3 sets Sterilizer with operation-lamp for field use 6 sets Operation-bed for field use 6 sets Stretcher 285 sets Operation-tent 3 sets Medical trunks for removing poisonous gas for Ambulance use 3 aets Oxygen inspirator 3 sets Oxygen respirator t qflfq Auto-respirator 3 3ets Water-supplier (B) 3 sets Officer's carrying bag 15 Bag for treatment 9 Bag of bandages 190 160 RESTRICTED M-AB EVCLOSDRE (C), continued 2. Cars Motor-car for removing poisonous gas 1 set, con- Boiler 1 sisting of Ambulance 36 three cars Cart 70 3. Baggage Tent for army use 6 sets Utensils Utensils Clothes in reserve Rice, wheat etc. Patient-clothes Table of Organization of the Ambulance (Field) Hospital Persons Riding horses Cart- horses Major (Medical) Captain (Medical) Lieutenants and Second Lieut’s (Medical) Captains, Lieutenants or Second Lieut’s (Pharmacist) Captains, Lieutenants or Second Lieut’s (not specialist) Non-commissioned medical officers Non-commissioned technical officers Medical men 1 (the chief) 3 3 10 2 2 1 (engaged in 30 supply) 2 126 1 2 Total 180 3 Non-commissioned officer (of Army Service Corps; 1 1 70 Men (of Army Service Corps) 89 5 Intendant officer 1 Non-commissioned intendant officers 2 Non-commissioned veterinary officer 1 Men in duty for horses 3 Total 97 6 70 Sum Total 9 70 277 79 M-AB RESTRICTED ENCLOSURE (CJ, continued Equipment of the Ambulance (Field) Hospital (table next page) 1, Medical stores Medical trunks for hospital use 2 sets Sterilizer with operation-lamp for field use 4 sets Operation-bed for field use 4 sets Stretchers 20 sets Operation tents 2 sets Microscope and its case 1 set Medical trunks for removing poisonous gas for hospital use 2 sets Oxygen inspirator 2 sets Auto-respirator 2 sets Water-supplier (B) 1 set X-ray apparatus for field use 1 set (only in the Fourth Hospital) Officer's carrying bags 17 Bags for treatment 10 Bags of bandages 26 Dental trunks 1 set 2. Cars Carts 68 Boilers 2 3. Baggages Patient-clothes 6 Tents for Army use Utensils Table-ware for patients Rice, wheat, supplementary food and horse- forage patient-food F. Some statistics with relation to the Second World War: (Statistical data of war-diseases as to areas, annuals, and kinds of sickness.) I Remarks: 1. The chief infective diseases include the following; plague, cholera, typhoid, paratyphoid, meningtls epidemica, dysentery, small-pox, scarlet- fever, diphtheria, eruptive fever and dengue-fever. 2. These statistical data have been made by investigating total numbers and percentages of cases as to areas all precise statistical materials being burned up by air-raids. It is regretful that we could not do otherwise at present, 3. Any disease more severe than drill-repose was Included in war di- seases, about 40$ of which were treated at hospitals. 162 RESTRICTED M-AB ENCLOSURE (C). continued Outbreak of war diseases in China Classification 1942 1943 1944 1945 Total % Main infectious diseases 13,903 13,360 14,296 13,010 54,569 2.0 Malaria 69,515 '66,800 71,480 65,050 272,845 10.0 Lung-T.B. 97,314 93,520 100,072 91,070 381,976 14.0 Pleuritls 55,612 53,440 57,184 52,040 218,276 8.0 Other T.B. 13,903 13,360 14,296 13,010 54,569 2.0 Beriberi 62,560 60,120 64,332 59,545 246,557 9.0 Other diseases relating to general condition of body 41.709 if0,080 42,888 39,030 163,707 6.0 Mental diseases 20,853 20,040 21,444 19,515 881,858 3.0 Other nervous diseases 34,755 33,400 35.740 32,525 136,420 5.0 Other diseases of resp. organs 41,709 40,080 42,888 39,030 163,707 6.0 Diseases of circulatory organs 27,806 26,720 28,592 26,020 109,138 4.0 Diseases of nutritive organs 55,612 53,440 57,184 52,040 213,276 8.0 Urinary and genital organs 10,426 10,020 10,722 10,737 40,926 1.5 Venereal diseases 4,170 4,008 4,211 3,903 16,369 0.6 Ophthalmic diseases 13,903 13,360 14,296 13,010 54,569 2.0 Otological diseases 2,780 2,674 2,859 2,602 10,915 0.4 Cutaneous diseases 10,426 10,020 10,722 9,757 40,925 1.5 Diseases of kinetic organs 20,853 20,040 21,444 19,515 81,852 3.0 Wounded 1,706 40,080 42,888 39,030 163,704 6.0 Other injuries 55,612 53,522 57,261 51,041 217,436 8.0- Total 695,127 668,O84 714,876 650,500 2,728,587 100.0 163 M-AB RESTRICTED ENCLOSURE (C), continued Outbreak of war diseases in south areas Classification 1942 1943 1944 1945 Total % Main Infective diseases 18,510 22,982 21,744 11,014 74,250 2.0 Malaria 185,100 229,820 217,440 110,140 742,500 20.0 Lung-T.B. 64,735 80,437 76,104 38,549 259,875 7.0 Pleuritis 37,020 45,964 43,488 22,028 148,500 4.0 Other T.B. 9,255 11,491 10,872 5,507 37,125 1.0 Beriberi 101,805 126,401 119,592 60,577 408,375 11.06 Other diseases relating to general condition of body 92,500 114,915 108,725 55,070 371,260 10.0 Mental diseases 27,765 34,473 32,616 16,521 111,375 3.0 Other nervous diseases 55,604 67,837 64,145 32,491 220,077 5.9 Other diseases of resp. organs 56,455 70,095 66,219 33,592 226,361 6.1 Diseases of circulatory organs 74,040 91,928 86,976 44,056 297,000 8.0 Diseases of nutritive organs 64,040 80,437 76,104 218,549 439,130 7.0 Urinary and genital organs 9,225 11,491 10,872 5,507 37,125 1.0 Venereal diseases 4,628 5,749 5,436 2,753 18,566 0.5 Ophthalmic diseases 10,180 12,640 11,959 6,057 40,836 1.1 Otological diseases 8,329 10,341 9,784 4,956 33,410 0.1 Cutaneous diseases 4,628 5,749 5,436 2,753 18,566 0.5 Diseases of kinetic organs 18,510 22,982 21.744 11,014 74,250 2.0 Wounded 46,275 57,490 54,360 27,530 185,655 5.0 Other Injuries 36,071 45,928 43,639 22,028 147,666 4.0 Total 924,805 1,149,150 1,087,255 730,692 3,891,902 100.0 164 RESTRICTED M-AB ENCLOSURE (C), continued Outbreak of war diseases in Manchuria Classification 19 k2 1943 1944 1945 Total % Main Infective diseases 9,100 8,000 8,180 4,100 29,380 2.0 Malaria 18,200 16,000 16,360 8,200 58.760 4.0 Lung-T.B. 113,750 100,000 102,250 51,250 367,250 25.0 Pleuritis 54,600 48,000 49,080 24,690 176,280 12.0 Other T.B, 9,100 8,000 8,180 4,100 29,380 2.0 Beriberi 27,300 24,000 24,540 12,300 88,140 6.0 Other diseases relating to general condition of body 31,350 28,000 28,630 14,350 102,830 7.0 Mental diseases 13,650 12,000 12,270 6,150 44,070 3.0 Other nervous diseases 2,750 20,000 20,450 10,250 73,450 5.0 Other diseases of resp. organs 27,300 24,000 24,540 12,300 88,140 6.0 Diseases of circulatory organs 18,200 16,000 16,360 8,200 58,140 6.0 Diseases of nutritive organs 22,750 20,000 20,450 10,250 73,450 5.0 Urinary and genital organs 5,460 4,800 4,908 2,460 17,628 1.2 Venereal diseases 3,135 2,800 2,863 1,435 10,283 0.7 Ophthalmic diseases 3,640 3,200 * 3,272 1,640 11,752 0.8 Otological diseases 1,365 1,200 1,227 615 4,407 0.3 Cutaneous diseases 6,825 6,000 6,135 3,075 22,035 1.5 Diseases of kinetic organs 11,375 10,000 10,225 5,125 36,725 2.5 Wounded 18,200 16,000 16,360 8,200 58,760 4.0 Other injuries 36,400 32,000 32,720 16,400 117,520 8.0 Total 455,000 400,000 409,000 205,000 1,469,000 100,0 165 M-AB RESTRICTED ENCLOSURE (C), continued Statistics of casualties as to cause in various places , by rifle by gun or cannon by explosion by close combat other total „ i China Wounded % nos. 60.8 53,504 21.4 18,83 2 11.3 9,944 0.5 440 6.0 $,280 100 88,000 Dead % nos. 77.2 33,968 11.1 4,88 4 8.1 3,564 1.0 440 2.6 1,144 100 44,000 South Wounded arn /° nos. 55.0 107,197 24.2 47,16 7 12.0 23,388 0.5 58$ 8.$ 16,$67 100 194,904 Dead lo nos. 58.2 262,119 14.6 65,75 5 24.3 109,442 0 0 2.9 13,061 100 4$0,377 Manchu- ria Wounded * nos. 4,641 Dead $ nos. 0 w V. « ode i 1,635 Results of the Wounded ; I Recovered Dead ] Repatriated Remained Total China 32.9/o 32.4% 14.7 20.0 100 South 17.1% 49.5% 19.3 13.1 100 Manchu- ria $0.2% 28.8 ~/o 18.1 2.9 100 Remark;: Results in Manchuria could not be considered to be exact. ■: 1 I i olmlfidldqC Results of War Diseases 1. Sum total during the war. 2. Results of in-patients only. r r\ . C* /S recovered dead sent to Japan proper remained China 87.7$ 0,8% 10.4$ 1.1$ Manchuria 91.5$ 0.6% 5.0$ 1 • 4$ South 88.0% 1.6 yo 5.9$ 4.5$ The materials concerning to Manchuria were presumed. 166 RESTRICTED M-AB ENCLOSURE (C). continued Result of repatriated patients from China Number of patients Recovery (*) dead d (£) ischarged MS) i leave hospital unrecovery (*) remain number Wounded 1 20,367 2,352 (11.55) 111 (0.54) 5,935 (39.39) 4,715 (23.15) 1,204 (35.37) 1941 Sick 69,980 23,120 (33.04) 2,563 (3.66) 14,009 (20.02) 12,605 (18.01) 17,683 (25.27) Wounded 11,834 877 ( 7.4D 111 (0.94) 3,444 (29.10) 2,548 (21.53) 4,854 (41.52) 1942 Sick 35,743 7,436 (20.30) 2,061 (5.77) 8,038 (22.49) 7,098 (19.81) 11,110 (31.08) Wounded 7,196 384 ( 5.34) 37 (0.51) 2,286 (31.77) 1,661 (23.08) 2,828 (39.30) 1943 V* Sick 26,239 5,354 (20.4 ) 1,784 (6.8 ) 6,023 (22.95) 6,525 (24.87) 553 (24.97) Wounded 8,563 687 ( 8.02) 71 (0.82) 2,418 (28.24) 2,017 (23.55) 3,370 (39.36) 1944 Sick c g c 29,048 8,289 (28.54) 11,921 (6.61) 7,120 (24.51) 5,338 (18.38) 6,380 (21.91) Wounded- 4,790 235 ( 4.91) 24 (0.5 ) 910 (19.0 ) 538 (11.23) 3,083 (64.36) 1945 until April Sick 14,895 2,582 (17.33) 310 (2.08) 2,043 (13.7D 2,020 (13.56) 7,940 (53.3D ‘Wounded 52,750 4,535 ( 8.60) 254 (0.67) 15,043 (28.52) 11,479 (21.76) 21,339 (40.45) total Sick 175,905 46,781 (21.59) 8,639 (4-91) 37,233 (21.17) 33,586 (19.09) V9,666 (23.23) total 228,655 51,316 (22.44) 8,993 (3.93) 52,276 (22.86) 40,065 (19.71) 71,005 (31.05) 167 M-AB RESTRICTED ENCLOSURE (C), continued Results of repatriated patients from southern territories Number of patients Recovery (*) dead it) discharged w leave hospital unrecovery i%) remain number on V/ounded 5,193 811 (18.6 ) 51 (0.98) 122 ( 2.35) 264 ( 5.08) 3,950 175.97) 1942 Sick 12,486 2,900 (23.78) 203 (1.63) 255 ( 2.04) 993 ( 7.95) 8,066 (64.60) V/ounded 8,570 1,306 (15.24) 49 (0.57) 1,430 (16.69) 2,210 (25.79) 3.575 (4i.72) 1943 Sick 37,131 13,223 (35.61) 853 (2.3 ) 2,488 ( 6.7 ) 6,911 (18.34) 13,656 (36.78) V/ounded 7,417 1,104 (14.88) 54 (0.73) 1,610 (21.71) 1,634 (22.03) 3,015 (40.55) 1944 Sick 37,169 15,260 (14.88) 992 (0.73) 2,573 (21.71) ,6,737 (22.03) 11,607 (40.65) V/ounded 4,208 828 (19.68) 41 (0.97) 233 ( 5.H) 328 ( 7.7 ) 2,773 (69.50) 1945 until April Sick 18,085 7,284 (40.08) 187 (1.02) 1,702 ( 1.41) 2,820 (15.59) 6,082 (33.69) Wounded 25,393 4,049 (15.95) 195 (0.77) 3,400 (13.39) 4,436 (17.47) 13,313 (52.43) total Sick 104,871 38,736 (36.94) 2,235 (2.13) 7,015 ( 6.69) 17,461 (16.65) 39,421 (37.59) total 130,264 42,785 (32.84) 2,430 (1.87) 10,418 ( 8.0 ) 21,897 (16.81) 52,734 (40.48) 168 RESTRICTED M-AB ENCLOSURE (CJ, continued Classification of diseases of repatriated patients froxa Manchuria Classification 1941 1942 1943 1944 1945 Total °/oo Infectious diseases 159 104 218 173 42 699 9.1 Malaria 37 43 86 30 17 213 2.3 Phthisis (T.B.) 4,272 7,731 6,472 6,987 1,404 26,868 349-8 Consumptive diseases except T. B. 1,729 1,968 1,586 1,724 304 7,311 95.2 Beriberi 391 507 437 473 67 1,875 24.4 Other diseases relating to general condition of body 257 381 344 367 52 1,401 18.2 Mental diseases 80 149 121 129 18 497 6.5 Other nervous diseases 745 1,220 699 970 128 3,762 49.0 Pleurisy 4,037 4,747 3,707 441 532 17,464 227.4 Other diseases of respiratory organs 335 539 695 480 129 2,228 29.0 Diseases of circulatory organs 168 348 266 277 41 1,100 14.3 Diseases of nutritive organs 502 764 610 721 73 2,670 34.3 Urinary and genital organs 165 233 259 252 38 1,002 13.0 Venereal diseases 100 143 126 127 22 518 6.7 Ophthalmic diseases 196 437 246 342 37 1,258 16.4 Otological diseases 115 147 94 121 28 505 6.6 Cutaneous diseases 73 85 80 72 8 318 4.1 Diseases of kinetic organs 145 198 180 161 23 707 9.2 Wounded 44 41 23 23 8 139 1.8 Accident injuries 796 1,171 1,093 972 177 4,209 54.8 Other injuries 594 291 692 370 121 2,063 26.9 Total 14,990 21,302 18,034 19,212 3,269 76,807 1000.0 169 M-AB RESTRICTED ENCLOSURE (C), continued Classification of diseases of repatriated patients from South-Areas Classification 1942 1943 1944 1945 Total °/oo Infectious diseases 111 621 793 67 1,592 18.7 Malaria 3,305 10,937 10,827 2,434 27,553 324.5 Phthisis (T.B.) 1,932 3,948 2,417 1,272 9,569 112.7 Consumptive diseases except T.B. • 420 1,024 710 184 2,333 27.5 Beriberi 487 1,634 2,003 224 4,353 51.3 Other diseases relating to general condition of body 282 633 477 198 1,590 18.7 Mental diseases 136 422 384 73 1,015 12.0 Other nervous diseases 513 860 930 207 2,515 29.6 Pleurisy 1,022 1,38 4 1,723 634 5,263 62.0 1 Other diseases of respiratory organ 489 565 472 189 1,715 20.0 ; Diseases of 1 circulatory organs 100 185 173 41 499 5.9 Diseases of the nutritive organs 620 1,207 1,479 218 3,524 41.5 Urinary and genital diseases 104 215 224 34 577 6.8 Venereal diseases 70 133 82 23 30 8 3.6 Ophthalmic diseases 164 342 193 52 751 3.8 Otologlcal diseases 104 204 172 . .. 37 517 6.1 Cutaneous diseases 63 141 69 21 299 3.5 Diseases of hinetic organs 198 334 243 113 888 10.5 Wounded 5,148 4,179 3,723 1,326 14,876 175.2 Accident injuries 1,181 1,335 1,401 293 4,215 50.C Other injuries 143 447 297 63 950 11.2 Total 16,602 31,250 23.797 3.253 34.907 1000.0 ... , | 170 RESTRICTED M-AB ENCLOSURE (C), continued G. Curriculum of Civilian L'edical Schools before and during the 'Jar for Doctors, Dentists and Nurses. 1, Doctors. a. middle school -- medical academy (4 years before the war, 3 years and a half during it.) b. middle school -- scientific section of high school medical college or medical section of university. (4 years before the war, 3 years and a half during it.) 2, Dentists. middle school dental academy (3 years before and during the war.) 3, Nurses. national school nurses* training school (both public and private, 2 or 3 years.) 171 RESTRICTED M-AB ENCLOSURE (D) RESTRICTED M-AB ENCLOSURE (D) TRANSLATION OF TITLES OF ARTICLES IN VARIOUS JAPANESE MEDICAL JOURNALS WHICH HAVE BEEN SUBMITTED TO WDC FOR FORWARDING TO ARMY MEDICAL LIBRARY TABLE OF CONTENTS Japanese Journal of Medical Sciences Page 174 The Japanese Journal of Urology Page 193 Bulletin of the Naval Medical Association Page 206 The Journal of Biochemistry Page 230 Acta Serologlca Et Immunologies Page 239 The Japanese Journal of Dermatology and Venereology Page 248 Japanese Journal of Zoology Page 250 The Japanese Journal of Experimental Medicine Page 252 173 M-AB RESTRICTED ENCLOSURE(D) TRANSLATION OS’ TITLES OF ARTICLES IN VARIOUS JAPANESE MEDICAL JOURNALS WHICH HAVE BEEN SUBMITTED TO WDC FOR FORWARDING TO ARMY MEDICAL LIBRARY JAPANESE JOURNAL CF MEDICAL SCIENCES Part 11, Biochemistry Vol. IV, No. 4 March, 19A1 CONTENTS AUTHOR ARTICLES TACHI, Y. ; Beitrage zur Bedeutung der Lipoide im tierischen Organismus. 1. Studien über den Gbolesteringelialt der Organe einiger Wildvogel. P. 233 TACHI, Y. : Beitrage zur Bedeutung der Lipoide im tierisciien Organismus. 2. Unterschied des Cholesteringehalts der verschiedenen Organs zwlscden Hausratte und weisser Ratte. P. 251 TAGHI, Y. : Beitrage zur Bedeutung der Lipoide im tierischen Organismus. 3. Über den Unterschied zwischen dem Ciiolesteringehalt des Beuge- und des Streckrnuskels einiger Tiere. P. 261 SATO, K. : ’A'achstum des Fettkorpers des amerikanischen Rlesenfroaches und dessen Inhalt. P. 273 SATO, K. : Effect on the blood oxalic acid of factors influencing the excretion of the acid into the urine. P. 277 KOYANAGI, J. FUKASAKO, T. : Biockemische Untersuchung über die Wirkung der Ultrakurz- wellen. I. Mitteilung. Einfluss der Durchflutung auf die Ausscheidung von Gesamtsticketoff, Harnstoff und Gesamtscii- welelsaure im Harn. P. 281 KAN, S. : Biochemische Untersuchung über die Wirking der Ultrakurz- wellen. 11. Mitteilung. Einfluss der Durchflutung der Milz des Hundes auf Lipoid-Phospber des Blutes. P. 291 End of Vol. IV, No. 4, March 1941 JAPANESE JOURNAL OF MEDICAL SCIENCES Fart 11, Biochemistry, Vol. V, No. 1 January, 1942 CONTENTS AUTHOR ARTICLES YOSHIMUHA, T.: Über die Veranderungen des Gehaltes an verscbiedenen phosphor- haltigen Verbindungen des Hubnerblutes wahrend der Entwicke- lung. P. 1 174 RESTRICTED M-AB ENCLOSURE ID), continued YOSHIMURA, T.: Über den Unterschied in dem Nukleoproteidphoephorgebalt der kernhaltigen und der kernlosen roten Blutkorperchen. P. 23 YOSHIMURA, T.: Über den Nukleoproteidphospborgebalt verschledener Organs von einigen Tieren. P. 33 OKUDA, H. : On the effect of heavy metallic salts upon the autoiidation of fruit juice vitamin C. P, 41 AMADA, Y. : Über die Pistelgalle des Kanincbens. 3. Mittellmg über Gallensaurestoffweobsel. P. 49 AMADA, Y. ; ITber die choleretische Wlrksamkeit einiger Oxycholansauren. U. Mitteilung über Gallenaaurestoffwechsel. P. 57 AMADA, Y. : Tiber die cholerotische Wirksamkeit einiger Ketocholansauren und deren Ausscheidung in die Galle. 5. Mitteilung über Gallensaurestoffwechsell. P. 71 End of Vol. V, No. 1, January, 1942 JAPANESE JOURNAL OF MEDICAL SCIENCES Part V, Pathology Vol. V. No. 1 March, 1940 CONTENTS AUTHOR ARTICLES OGATA, T. : liber die Systems into Hung der bamatopoetiscben Gewebe. P. 1 YA, S. : liber elnen Fall von Zystenlunge. F. 13 OGATA, T. ; The Shwartzman Type of Skin Reaction by Means of Various Body Fluids. P. 25 OGATA, T. : Über die Weedselbeziehungen zwischen der lokalen Hautwirkung von Diptberietoxln und der Gewebsumstimmung durcli Shwartzman- Filtrate. P. 49 YOSHIDA, T. : Über die Myokardveranderung bel der progressive!! Muskeldys- trophie. End of Vol. V, No. 1, March, 1940 175 M-AB RESTRICTED ENCLOSURE (D), continued JAPANESE JOURNAL OF MEDICAL SCIENCES Part V, Pathology Vol. V, No. 2 August, 1940 CONTENTS AUTHOR ARTICLES MATSUDA, K. : Über eigenartige, Retoenolsubstanz fuhrende braunliche Kor- perchan in den menschlichen Adergeflechten. P. 69 MARUYA, H. : Morphological Studies on the Development of Liver Cancer by Butter Yellow. P. 83 HAMAZARI, Y. & MATSUDA, K. : Über das Retoenolsubstanz fuhrende Kanalchensystem im Epithel des Plexus choriodie. P. 107 IWASAKI, T. : Studien über die Pleuraverwachsung, insbesondere die der so- genannten idiopathischen Pleuritis. P, 115 OKABAYASHI, T.; Experimentelle Erzeugung von diffuser Glomerulonephritis mit Herzaffektion durch Streptokokkeninfektion der Nasenhohle (Nasennebenhohle-Fenster-Methode) bei Kaninchen. (Experi- mentelle Fokalinfektion.} P. 131 End of Vol. V, No. 2, August, 1940 JAPANESE JOURNAL OF MEDICAL SCIENCES Part V, Pathology Vol. V, No. 3 October, 1940 CONTENTS AUTHOR ARTICLES YOSKIHIKO NAGAHARA : Experimentelle Studien über die histologischen Veranderungen des Geruchsorgans nach der Olfactoriusdurchschneidung. Beit- ragezur Renntnis des feineren Baus des Geruchsorgans. (Über die Kiechschleimhaut bei Sommerencephalitis.) P. 165 TEI-JU ITARURA : The Histo-pathological Studies on Teeth of the Lepers, Espe- cially on Its Gingiva and Other Supporting Tissues. P. 201 IKUO NISHIMURA: A Clinical Report on the Aniline Bladder Tumours (Four Oases). P. 221 End of Vol. V, No. 3. October, 1940 176 RESTRICTED M-AB ENCLOSURE (D), continued JAPANESE JOURNAL OF MEDICAL SCIENCES Part V, Pathology Vol. V, No. 4 December, 1940 CONTENTS AUTHOR ARTICLES TAKEDA, K. : Über die Bedeutung der allergischen Gewebsreaktion bei der Entstehung der Tuberkulose. I. Mltteilung, Über die tuber- kulose Allergie der serosen Elache (Pleura, Meningen und Gelenk) unter Beruchsichtigung der Serumallergie derselben. P. 227 MUTO, K. : Beitrag zur pathologischen Anatomie der Diphtherie, mit be- sonderer Berucksichtigung der Veranderungen des lymphatisc- hen Gewebes. P. 259 NITTONO, P. & HOSHIYAMA, J. : Ein Sektionsfall von rheumatischer Pneumonie. P. 31$ AMANO, S : Statistisch pathologisch-anatomische sowie hamatologische Untersuchungen über das Wesen der Leukamie. (I, Hauptteil der Pathologie der Leukamie.) P. 331 End of Vol. V, No. 4, December, 1940 JAPANESE JOURNAL OF MEDICAL SCIENCES Part V, Pathology Vol. VI, No. 1 October, 1941 CONTENTS AUTHOR ARTICLES NUMOI, S. : Histologisohe und cytologische Untersuchungen über die Nebe- nnlerenrinde der Maus, zugleich über das Auftreten von Ade- nomknoten der Rinde bei kastrierten Mauschen, P, 1 MARUYA, H. & TANAKA, S. : On the Distant Carcinogenic Effect of Butter Yellow. P. 69 KlißO, M. : The Cause of the Dermatitis in Manchoukuo. P. 75 KATASE, A. & BABA, T. ; Experimentell erzeugter Hydrozephalus mit besonderer Beruck- sicktigung der Atiologie des Hydrocephalus congenitus. P. 79 SHINDO, H. : On Panhemat©phthisis, P, 91 End of Vol. 71* No. 1, October, 1941 177 M-AB RESTRICTED ENCLOSURE ID), continued JAPANESE JOURNAL OF MEDICAL SCIENCES Part V, Pathology Vol. VI, No. 2 December, 1941 CONTENT AUTHOR ARTICLES TOKORO, Y. ; Pathologisch-histologlsche Untersuchungen über die primaren neurogliogenen Geschwulste des Zentralnervensysterns. P. 103 TWATA, K. ; Untersuchungen über die hyalintropfige Degeneration in den Epithelien des Harnkanalchens, Quantitative Veranderungen beim Wechsel der Jahreszeit in normalen Kroten. P. 161 MARUTANI, N. & MINAMI, S. : Ein Sektlonsfall von primarem Lebersarkom mit Metastase in Herzen. P. 175 End of Vol. VI, No, 2, December, 1941 JAPANESE JOURNAL OP MEDICAL SCIENCES Part V, Pathology Vol. VI, No. 3 September, 1942 CONTENTS AUTHOR ARTICLES KOBAYASHI, H. ; Studies on Trematoda in Hainan Island. I. Determination of the second intermediate hosts of trematodes and trematodes found in the intestinal tract of dogs by experimental feeding with fish in Halnan-Island. P. 181 KOBAYASHI, H. : Studies on Trematoda in Hainan Island. 11. Trematoda found in the intestinal tracts of dogs by experimental feeding with certain fresh and brackish water fishes. P. 187 TSUTSUI, Z. : Über die Histogonese der Tuberkel der Lunge mlt besonderer Beruckslchtigung der Neubildung der Silberfaser. P. 229 >End of Vol. VI, No. 3, September, 1942 178 RESTRICTED M-AB ENCLOSURE ID), continued JAPANESE JOURNAL OF MEDICAL SCIENCES Part V, Pathology Vol. VI, No. 4 September, 1942 CONTENTS AUTHOR ARTICLES Pathological Papers published in Japan during 1939. P. 1 End of Vol. VI, No. 4, September, 1942 JAPANESE JOURNAL OF MEDICAL SCIENCES Part V, Pathology Vol. VII, No. 1 November, 1942 CONTENTS AUTHOR ARTICLES MAKING, N. : Histologiscbe Studien über das Wesen des sogenannten Shwartz- man pbanomens, P. 1 TAKEDA, K, : Ueber die Bedeutung der allergiscben Gewebsreaktion bei der Entstebung der Tuberkulose. 11. Mitteilung: Ueber die tuberkulose Allergie der Lunge bei Kanincben, unter besond- erer Berucksichtigung der Entstebung der kasigen und der fibrinosen Pneumonle. P. 47 End of Vol. VII, No. 1, November, 1942 JAPANESE JOURNAL OF MEDICAL SCIENCES Part V, Pathology Vol. VII, No. 2 February, 1943 CONTENTS AUTHOR ARTICLES TAKAKI, F. : Morpbologiscbe Studien über die experimentelle japanische epidemiscbe Encephalitis (Sommerencephalitis). SAKAMOTO, A. MIYAGAWA, H. SATO, J. & OKUDA, Y. ; Experimentelle Studie über die Leukosen. P. 143 End of Vol. VII, No. 2, February, 1943 179 M-AB RESTRICTED ENCLOSURE (D), continued JAPANESE JOURNAL OF MEDICAL SCIENCES Part V, Pathology Vol. VII, No. 3 March; 1943 CONTENTS AUTHOR ARTICLES KOBAYASHI, C. ; On Endemic Goitre of Hogs in Goitrous Regions of Formosa (Taiwan), Japan. P. 161 INDGAMI, K. : Tiber Endocarditis verrucosa bei Tuberkulosefalien, insbeson- dere die Beziehung Zwischen Endocarditis und Tuberkulosefor- men bzw. rheumatischen Granulomen im Myokard. P. 185 HAMAZAKI, Y. WATANABE, T. & NAGASE, S. ; Ueber eigentumliche Kerneinschlusse, die bei an japanisoher bzw. amerikanischer Encephalitis epidemics erkrankten Mausen gefunden wurden. IV, Mitt.: Zeitliche Verfolgung des Auftretens der Kerneinschlusse im Bereich von Ohr und Nase. P. 191 End of Vol. VII, No. 3, March, 1943 JAPANESE JOURNAL OF MEDICAL SCIENCES Part V, Pathology Vol. VII, No. 4 December, 1944 CONTENTS AUTHOR ARTICLES TSTJNEMATSU, K.: Über die funktionelle Bedeutung der Shrapnellschen Membran des Trommefelles. P. 20? HAMAZAKI, Y. OKUDA, K. & YAMADA, K. : Tiber die lokale Kernelnschlussbildung der Impfstelle des Virus der epidemischen Encephalitis. P. 219 HAMAZAKI, Y. : Tiber die new entdeckten spezifischen Kerneinschlusskorper- cnen bei an Choriomeningitis erkrankten Mausen. P. 231 HAMAZAKI, Y. FUJIOKA, H. & SUGIHARA, T. : Tiber die spezifischen Kerneinschlusskorperchen bei an japan- ischer Oder amerikanischer Encephalitis epidemioa erkrankten Mausen. VII. Mitteilung entstehungsmechanismus der Kernei- nschlusskorperchen bei intravenoser Impfung des Virus. P. 243 End of Vol. VII, No. 4, December, 1944 180 RESTRICTED M-AB ENCLOSURE ID), continued JAPANESE JOURNAL OF MEDICAL SCIENCES Part VI, Bacteriology Sc Parasitology Vol. I, No. 4 January, 1940 CONTENTS AUTHOR ARTICLES CGASAV/ARA, K. 4. TSURUMI, M. : Studies on Influenza Virus (Feurth Report). A minute Corpus- cle in Lung Lesion of Mice Infected by Influenza Virus, P. 153 ZEN, T. Sc NOKI, Y. : Zur Bedeutung des Medium-pH bei der Extraktlon antigener Bak- terienleibsubstanzen (Experimente betreffs der analysierten Typhusbazillen-Antigene). P. 159 YAMAGUCHI, 3.: Studies on the Helminth Fauna of Japan. Part 30. Cestodes of Birds, 11. P. 175 YAMAGUCHI, S. Sc MIYATA, I. : Nippotaenia mogurnda n, sp. (Cestoda) from Mogurnda obscura \Temm, et Schleg,). P, 213 ACKI, Y. Sc SAI, Z. : Zur AnwendbarKelt der Osmesetheorie auf das Prazlpitemeter- Zentrifugat, das den 1m Standardmedlum unserer Farstoffreak- tion suspendierten Bakterien entstammt. P. 215 YAMAHA, M. : Experimental Studies on the Mechanism of Vaccinial Immunity. On the Immunological Significance of the Filterable and Non- inf ective Substance in Vaccinial Suspensions. P. 227 End of Part VI, Bacteriology Sc Parasitology, Vol. 1, No. A, January, 1940. JAPANESE JOURNAL OF MEDICAL SCIENCES Part VI, Bacteriology Sc Parasitology Vol. 11, No. 1 March, 1941 CONTENTS AUTHOR ARTICLES TSURULII, M. OGASAWARA, K. FUJII, K. & SASAKI, Y. : Studies on Influenza Virus (Fifth Report). Findings on the Elementary Bodies of Influenza Virus. P. 1 ISHIGURO, K. : Preservation of Complement by Drying it from the Frozen State. P. 9 181 M-AB RESTRICTED ENCLOSURE (D), continued AOKI, Y. & CHIN, R. : Über die Adsorptionsfahigheit von Kaolin gegenuber Typhus- teilagglutinlnen. P. 27 OTA, 1.. & FUKUDA, M. : Umschlag aus der Rauhform von Ohta-Ruhrbazillen in die Glatt- form vermittels Kultivierung in der mit abgetoteten hetero- logen Baktorienleibern versetzten Bouillon (Verfahren von Habs and Seitz). P. 35 AOKI, Y. KANEMITSU, J. : Zur Bedeutung des Medium-pH bei dem Übergang antigener, das : Verwandtschaftsverhaltnis bekundener Serumsubstanzen. P. 43 NAITO, T. & CHIN, R. ; Beitrage zur Kenntnis über die Agglutination von Sphictero- haemorrhagiae. Vorschlag einer Methods zur Abschatzung der Agglutination mit blossem Auge. P, $9 End of Vol, 11, No. 1, March, 1941 JAPANESE JOURNAL OF MEDICAL SCIENCES Part VI, Bacteriology & Parasitology Vol. 11, No. 2 torch, 1942 CONTENTS AUTHOR ARTICLES MATUBAYASHI, H. Studies on Dientamoeba fragilis with Special Reference to Viability Outside the Host, P. 67 YASUDA, S. : Experimentelle Studien über die Recktinogenaviditat des Antigens von Nakamura fur seine Sofortige Reaktion auf Typhus und Paratyphus. P. 8$ End of Vol. 11, No. 2, March, 1942 JAPANESE JOURNAL OF MEDICAL SCIENCES Part VI, Bacteriology &, Parasitology Vol. 11, No. 3 September, 1942 CONTENTS AUTHOR ARTICLES YAMAGUCHI, S. : Some nematode parasites from domestic animals of tonchoukuo. P. 95 YAMAGUCHI, S. : Studies on the Helminth Fauna of Japan. Part 37. Trematodes of Fishes, VIII. P. 10$ YAMAGUCHI, S. : Studies on the Helminth Fauna of Japan. Part 38. Larval Trematodes of Fishes. P. 131 182 RESTRICTED M-AB ENCLOSURE (D), continued TAKEUCHI, E. ; New Blood-Flukes of the Family Spirorchidae from Japanese Fresh-water Tortoise and Marine Turtles, P. 161 KANEDA, N. : Immunologjsche Studien über den wasserloslichen Bestandteil des Stuhles bei der bazillaren Dysenterie. I. Mitteilung. Antigenanalyse des Stuhles von einem Komagome-8111-Ruhrfall (Versuche seitens des Reaktinogens und des Immunogens). P. 175 SHIRAISHI, N. ; Experimentelle Studien über die elektive Anreicherung von Pathogenen Darmbakterien im Wasser. I, Mittellung. Zur Moglichkeit der elektiven Anreicherung auf Grund der Lage- differenz des isoelektrischen Pxmktes je nach der Artens der Bakterien. P. 189 HAKAZAKI, Y. NAGASE, S. & WATANABE, T. • Über eigemtumliche Kerneinschlusse, die bei an japanisoher Encephalitis epidemica erkankten Mausen gefunder wurden. V. Mitteilung. Zeitliche Verfolgung des Auftretens der Ker- neinschlusse in Zentralnervensystem. P. 20$ KUWAHATA, M. ; Studien über die Paratyphus-Enterltis-Erreger, welche auf dem chinesischen Festland und in Mandschukuo herausgezuchtet wurden. I. Mittellung. Typeneinteilung der im Jahre 1940 in Mandschukuo und in Shanghai gewonnenen Stamme. P. 221 KANEDA, A. : Immunologische Studien über den wasserloslichen bestandteil des Stuhles bei der bazillarem Dysenterie. 11. Mitterlung. Antigenanalyse des Stuhles von einem Komagome-8111-Ruhrfall (Studien seitens des Antikorperabsorbens). P. 233 End of Vol, 11, No. 3, September, 1942 JAPANESE JOURNAL OF MEDICAL SCIENCES Part VI, Bacteriology & Parasitology Vol. 11, No. 4 February, 1944 CONTENTS AUTHOR ARTICLES HIMURA, R. HIGASHI, N. & AKAZAWA, H. : Über die Zuchtung des Denguevirus auf der Chorioallantois- membran von Hubnereiern. P. 241 KAMAZAKI, Y. NAGASE, S. TAKAME, S. : Über die Einflusse des Virulicidins auf die Kernelnschluss- korperchen von Encephalitis epidemica. P, 247 End of Vol. 11, No. 4, February, 1944 183 M-AB RESTRICTED ENCLOSURE (D), continued JAPANESE JOURNAL OF MEDICAL SCIENCES Part VII, Social Medicine and Hygiene Vol. 111, No. 3 December, 1940 CONTENTS AUTHOR ARTICLES UYEYAMA, R. : Über das normale typenspezifische Pracipitin. P. 13-22 UYEYAMA, R. : Studien über die neuen Typensubstanzen in Sekreten. P. 23-25 End of Vol. 111, No. 3, December, 1940 JAPANESE JOURNAL OF MEDICAL SCIENCES Part VII, Social Medicine and Hygiene Vol. IV, No. 1 March, 1943 CONTENTS AUTHOR ARTICLES TERAJIMA, M. : Analyse der A-Typensubstanzen im Blutkorperchen und in den Organen von Menschen sowie Tieren. P. 1-9 KOIZUMI, T. : Erbbiologische Studien über des Wirbelmuster. P, 11-18 End of Vol. IV, No. 1, March, 1943 JAPANESE JOURNAL OF MEDICAL SCIENCES Part VIII, Internal Medicine, Pediatry and Psychiatry Vol. VI, No. 1 March, 1943 CONTENTS AUTHOR ARTICLES TORIKAI, T. : Experimentelle Studien über die antithyreotrope Substanz. P. 1 TAMAI, M. ; Studies on blood and urinary amylase. 11. The urinary amy- lase as a functional test of the kidney. A clinical observa- tion. P. 21 ISHIMORI, K. : Beitraf zur Kenntnis des Electrencephalogramms. P. 31 TAMAI, M. : Studies on blood and urinary amylase. 111. Amylase clearance at highly elevated level of blood amylase. P, 41 184 RESTRICTED M-AB ENCLOSURE (D), continued HEKI, M. & OSHIMA : Nachweis der Gallensauren 1m Earn. P. 51 KA’A'AI, M. : Ciiemotlierapeutische Studien gegen Tuberkulose. IV. Mittei- lung. Die Wirksamkeit einiger Derivate von Aminopyrldin gegan Tuberkulose. P. 55 End of Vol. VI, No. 1, March, 1943 JAPANESE JOURNAL OF MEDICAL SCIENCES Part VIII, Internal Medicine, Pediatry and Psychiatry Vol. VI, No. 2 March, 1943 CONTENTS AUTHOR ARTICLES KAWAI, M. ; Chemotherapeutische Studien über Tuberkulose. Y, Mittei- lung. Die Wirkung von Aminochinolinen und ihrer Methyl- jodide. P. 61 NAKAGEN, S. : Chemotherapeutische Studien über Tuberkulose. VI. Mlttei- lung. Die Spezifizitat der Wlrkung von 3, 6-Dlamlnoacri- dinium-10-methyljodid bezuglich der wachstumhemmung der TBK- Bacillen. P. 69 HEKI, M. : Die Gallensauren in dem Duodenalsalt, bes, bei Cholecystitis- Fallen. P. 83 TAMAI, M. : A therodynamical treatment of renal function; with special reference to isosthenuria. P. 91 ISKII, K. : Über die Pathogenese des Schwarzwasserfiebers. F. 103 .2nd. of Vol. VI. No. 2, March, 1943 Japanese Journal of medical sciences Part IX, Surgery, Orthopedy, & Odontology Vol. V, No. 3 December, 1941 CONTENTS AUTHOR ARTICLES KUWABARA, S. ; Q,uelques alterations des cheveux au goitre exophtalmique. P. 75 SAGARA, Y, : Untersuchung über die Prophylaxe und Theraple der Thrombose. F. 85 SAGARA, Y. : Klinische Erfahrungen über die Venentbrombose mit besonderer der Therapie. P, 103 End of Vol. V, No. 3> December, 1941 185 M-AB RESTRICTED ENCLOSURE ID), continued JAPANESE JOURNAL OF MEDICAL SCIENCES Part IX, Surgery, Orthopedics & Odontology Vol. VI, No. 2 November, 1943 CONTENTS AUTHOR ARTICLES SATO, S. : P. 1 KUWABARA, S. : Valeur diagnostique de la resistance electrique de goitre exophtalmique au courant alternatif. P, 77 End of Vol. VI, No. 2, November, 1943 JAPANESE JOURNAL OF MEDICAL SCIENCES Part X, Ophthalmology Vol. 11, No. 2 March, 1940 CONTENTS AUTHOR ARTICLES : Abstracts of ophthalmological papers published in Japan during 1935 and 1936. End of Vol. 11, No. 2, March, 1940 JAPANESE JOURNAL OP MEDICAL SCIENCES Part X, Ophthalmology Vol. 111, No. 1 March, 1942 CONTENTS AUTHOR ARTICLES : Abstracts of ophthalmologleal papers published in Janan during 1937 and 1938. End of Vol. 111, No. 1, March, 1942 186 RESTRICTED M-AB ENCLOSURE ID), continued JAPANESE JOURNAL OF MEDICAL SCIENCES Part X, Ophthalmology Vol. 111, No. 2 July, 1943 CONTENTS AUTHOR ARTICLES OKADA, K. & HAMAZAKI, Y. : Über die neurozytophoben Kerneinschlusse (Hamazaki) 1m Augen- gewebe der mit Encephalitis epldemica infizierten Mause. P. 1 Abstracts of ophthalmological papers published in Japan dur- ing 1939 and 1940. End of Vol. 111, No. 2, July, 1943 JAPANESE JOURNAL OF MEDICAL SCIENCES Part X, Ophthalmology Vol. IV, No. 1 July, 1944 CONTENTS AUTHOR ARTICLES ; Abstracts of ophthalmological papers published in Japan dur- ing 1941- End of Vol. IV, No. 1, July, 1944 JAPANESE JOURNAL OF MEDICAL SCIENCES Part X, Ophthalmology Vol. IV, No. 2 December, 1944 CONTENTS AUTHOR ARTICLES : Abstracts of ophthalmological papers published in Japan dur- ing 1942. End of Vol. IV, No. 2, December, 1944 187 M-AB RESTRICTED ENCLOSURE ID), continued JAPANESE JOURNAL OF MEDICAL SCIENCES Part XI, Gynecology and Tocology Vol. 11, No. 3 December, 1941 CONTENTS AUTHOR ARTICLES MAGARA, M. RIN, R. OKAMOTO, E. : A Study on a Cause of Abruption Placentae and Abortion. KAMAMURA, H. : On the Antagonistic Substance against Pituitrin in the Living Body, Part 1. The New Knowledge about the existence of the Antagonistic Substance against Pituitrin, P. 27 KAMAMURA, H. : On the Antagonistic Substance against Pituitrin in the Living Body. Part 11. Correlation between the Anti-Pituitrin Sub- stance and Pituitrin-Sensitivity of the Rabbit’s Uterus in Various Periods of the Pregnancy, P. 39 KAMAMURA, H. ; On the Antagonistic Substance against Pituitrin in the Living Body. Part 111, The Mechanism of Part uritlon from the Viewpoint of the Anti-Pituitrin Substance. P. 53 End of Vol. 11, No. 3, December, 1941 JAPANESE JOURNAL OE MEDICAL SCIENCES Part Xl, Gynecology and Tocology Vol. 11, No. 1 January, 1940 CONTENTS AUTHOR ARTICLES : Abstracts of Gynecological and Tocological Papers published in Japan during 1937* P. 1 End of Vol. 11, No. 1, January, 1940 JAPANESE JOURNAL OF MEDIC AX SCIENCES Part XI, Gynecology and Tocology Vol. 11, No. 2 February, 1941 CONTENTS AUTHOR ARTICLES MAGARA, M. : Recherches sur les cocci anaerobles de vagin de femmes nor- males et pathologiques. P, 1 188 RESTRICTED M-AB ENCLOSURE (D), con tinned OKAZAKI, S. ; Intravessel Hydatiform Mole and Ectopic Chorio-Epithelioma NIU, H. grown together in the Cardinal Ligament. Supplement; Ques- tions upon Metastasis of Clorio-Eplthelioma. P. 11 End of Vol. 11, No. 2, February, 1941 JAPANESE JOURNAL OF MEDICAL SCIENCES Part XII, Oto-Rhino-Laryngology Vol. 111, No. 1-2 April, 1940 CONTENTS Index of Subjects P. 1 Index of personal Names P. 43 End of Vol. 111, No. 1-2, April, 1940 JAPANESE JOURNAL OF MEDICAL SCIENCES Part XII, Oto-Rhino-Laryngology Vol. IV, No. 1 March, 1942 CONTENTS AUTHOR ARTICLES FUJIME F. Sc ONISHI, Y. : Maladie de I'oreille interne causee par la leucemie myeloide chronique, P. 1 FUJIMI, F. & UMEHARA, N. : Mastoidite qui a eclate au cours de "Kala-azar". P. 17 NIHO, S. : Einfluss der Kalte auf den Drehnachnystagmus. P. 23 End of Vol, IV, No. 1, March, 1942 189 M-AB RESTRICTED ENCLOSURE (D), continued JAPANESE JOURNAL OF MEDICAL SCIENCES Part XII, Oto-Rhino-Laryngology Vol. IV, No. 2 March, 1944 CONTENTS Proceedings of the Japanese Oto-Rhino-Laryngological Society, The XLIIth Annual Meeting, 1938, in Kioto. P. 1 The XLIIIth Annual Meeting, 1939, in Cheba. P. 58 Index of Titles. P. 1 Index of Authors. P. 13 End of Vol. IV, No. 2, March, 1944 JAPANESE JOURNAL OF MEDICAL SCIENCES Part XIII, Dermatology and Urology Vol. 11, No. 1 December, 1940 CONTENTS AUTHOR ARTICLES KITAMURA, K. HORIGUCHI, Y. : Gleichseitige Haut-und Hoden-metastase eines Adenokarzinoms. P. 1 ; Bemerkungen zur etiologie und pathogenese des Erytbemazodes. P. 9 YAMANOUCHI, G. ITO, H. KOJIMA., R. • Ein Fall von Urticaria pigmentosa mit Teleangiektasie. Zugleich über die Klassifikation der Urticaria pigmentosa sowie den Zusammenhang derselben mit der Teleangiektasle. P. 15 KOJIMA, R. : Ein Beitrag zur Erytbrodermia exfoliativa, besonders über ibre Beziehungen zur Nebennierenrinde. P. 25 HAMIKI, J. : Tiber eine neue statische Untersuchungsmethode der Behand- lungsresultate von Krankheiten, angevmndt auf unsere antilu- etische Kun bei geringerem Untersuchungsmaterial. P. 35 YANG, R. T. : Some Clinical Observations and Opinions on tbe Subject of Atriplicism. P. $3 KAWAKURA, T. : Pourneville-Pringlesche Phakomatose mit Mierentumor. P. 65 YAMA2AKI, J. NAKANO, I. ; Eine Fall von Lymphocytoma tumidum facei. P. 77 ; Tiber eine trichophytieahnliche Hauterkrankung bei einem Manne, Hervorgerufen durch eine Varietat des Bacillus mesen- tericus, P, 83 KANDA, B. OTA, M. 190 RESTRICTED M-AB ENCLOSURE (D), continued TAKAHASHI, A. IWASHITA, K. Gekreuzte Ektopie der Niere. P. 93 TSUCHIYa, F. OIMORI, S. : Über die Toxitat von Sulfonamldverbindungen, vom Standpunkt des Reststicksteffes des Blutes betracbtet. P. 113 SAITO, R. SATO, S. KAWAMURA, T. NAKANC, I. : Über das gleicbzeitige Vorkommen von Tuberkulose und Konkre- menten in einer und derselben Niere. P. 131 End of Vol. 11, No. 1, December, 1940 JAPANESE JOURNAL OF MEDICAL SCIENCES Part XIII, Dermatology and Urology Vol. 11, No. 2 June, 1941 CONTENTS AUTHOR ARTICLES : Über die Gescbwursbildung durcb subkutane Injektion des B. C. G. P. 145 KOYAMA, S. KAGAYA, J. : Über die neue statistiscbe Untersuchungsmetbode der Beband- lungsresultate von Krankheiten. 11, Mitteilung des Beband- lungresultates der Syphiliskranken, die wahrend dieser 11 Jabre durcb eine kontinuierlicbe antiluetische Kur von Prof, Hasbimoto behondelt warden. P. 153 SUZUKI, S. : Beitrag zur Kenntnis des Scbweissdrunsencarcinoms, mit bes- onderer Berucksicbtigung Seiner hastologischen Einteilung, P. 165 YaMAZAKI, J. GARADA, G. : Zwei Falle von Boeckschem Sarkoid mit positivem Tuberkel- bazillenbefund im Herde. P. 177 SUZUKI, ’S. NOMURA, Y. OHASHI, K. KOBAYASHI, R. : Gleichzeitiges Vorkommen von Sarkom und Tuberkulose in ein und derselben Niere. P. 183 TAKAHASHI, A. KUSUNOKI, T. TOZAMA, K. : Harnsteinkrankheit in Tokyo. P. 19$ TSUCHIYA, F. SHINDO, H. : Kliniscbe Beitrage zur Kenntnis von Myxom des Samenstrangs. P. 201 IWASHITA, K. MIZOGUCHI, S, YASUDA, T. : Behandlung der mannlichen Gonorrhoe durch intravenose Vera- brei chung des Paraaminobenzolsulfoacetamids. P. 213 191 M-AB RESTRICTED ENCLOSURE (D), continued SAITO, H. : Über die Kliniscbe und dlagnostiscbe Bedeutung des Schramm- scben Symptoms, P. 219 OMORI, S. : Kliniscbe und experimentelle Studien über die Behandlung und den Helungsmechanismus durcb Druckelnspritzung von Arzneilo- sung in das Nierebecken. P. 223 End of Vol. 11, No, 2, June, 1941 JAPANESE JOURNAL OF MEDICAL SCIENCES Part XIII, Dermatology and Urology Vol. XII, No. 3 August, 1942 CONTENTS AUTHOR ARTICLES MIURA, 0. MATSUOKA, S. : Ein seltener, an eine Lympbdrusen-tuberkulose um den Samen- strang errinnernder Fall von Nicolas-Favre* sober Krankheit. P. 235 MINAMI, S. WADA, T. : Über das Cbloasma palpebrarum. P, 241 MITSUMOTO, S. : Haut nnd Histamin. P. 247 KIRISHIMA, M. : Lichen ruber planus mit Blaseneruption. P, 263 KIRISHIMA, M. : Naevus lichenoides systematisatus. P. 281 KATSU, T. : Eine Art von Naevi epitbeliomatosi; Naevus epitbeliomatosus melanocystopbyallnicus. P. 293 TAMAE, N. ; Experimentelle Untersucbung über die Hodenallergie gegen Tuberkelbazlllengift. P. 303. YAMAMURA, T. ; Über den Einfluss der einseitigen Nierentuberkulose auf die Gewebsatmung der Leber und der Nieren. P, 317 TSUCHIYA, F. OMORI, S. . JINDO, P. SATO, S. YASUDA, T. MORIOKA, T. : Über die Forschungen der Sulfonamidverbindungen 1m Gebiete der Urologe und in ihrem Grenzgeblete. P, 321 OTA, M. YASUDA, T. : Drei Falle von Ehlers-Denlosschem Syndrem, P. 3AO YAMAMURA, T. : Experimentelle Studien über die Wirkung des Dermatitlsserums. P. 365 End of Vol. 11, No. 3» August, 1942 192 RESTRICTED M-AB ENCLOSURE (D), continued THE JAPANESE JOURNAL OF UROLOGY Vol. 31, No. 1 July, 1941 CONTENTS AUTHOR ARTICLES OCHIAI, K. ; Klinische Studien der Hydronephrose. I. Mitteilung: Inter- mittierende Hydronephrose. P. 1 TSUCHIYA, F. SHINDO, H. : Klinische Beitrage zur Kenntnis yon Myxom des Samenstrangs. P. 9 HIROSE, Y. : Über die Verletzungen der Harnorgane im jetzigen japanisch chinesischen Kriege. P. 32 KABO, K. : Kinema auf dem Gebiet der Urologie. P. 34 End of Vol. 31, No. 1, July, 1941 THE JAPANESE JOURNAL OF UROLOGY Vol. 31, No. 2 August, 1941 CONTENTS AUTHOR ARTICLES IWASHITA, K. : Beitrag zur Kenntnis der Nierenvenenthrombose. P. 75 HARADA, G. SHIKIMURA, T. : Ein Fall von Priapismus, verursacht durch das rethotelsarkom (Reticulosarkom) der Schwellkorper. P. 89 NONAKA, Y. YAMAZOE, F. KURODA, K. : Ein Fall von angeborenem Nierenkelchdivertikel. P. 108 INAGAKI, Y. : Über einen Fall von Divertikelsteln der Harnblase. P. 118 End of Vol. 31, No. 2, August, 1941 THE JAPANESE JOURNAL OF UROLOGY Vol. 31, No. 3, September, 1941 CONTENTS AUTHOR ARTICUIS TANAE, N. : Experimentelle Untersuchung über die Hodenallergie gegen Tuberkelbazillengift. 11. Mitteilung: Beobachtungdurch Fruhveranderung (besonders durch hyperergische Entzundung) P. 147 193 M-AB RESTRICTED ENCLOSURE (D), continued YAMAMOTO, K. : Ein Fall von postcavalem Ureter. P. 169 SATO, A. : Sphincterometry. P. 169 SAKAI, S. : Über Blasengeschwulste. I. Teil: Zur Klinik und Statistik der Blasengeschwulste. P. 187 End of Vol, 31, No. 3, September, 1941 THE JAPANESE JOURNAL OF UROLOGY Vol. 31, No. 4 October, 1941 CONTENTS AUTHOR ARTICLES MAEHARA, H. : Über die Leistung der Saure-Alkali- Umschlagsprobe zur Erken- nung der Nierenerkankungen. P, 231 IWASHITA, K. YONEYAMA, S. : Beitrag zur Kenntnis der pediatrischen Urologie. I. Mit- teilung: Statistische Beobachtungen über Cystitis acuta in- fantum. P. 260 YAMAMURA, T. : Über den Einfluss der Einseitigen Nierentuberkulose auf die Gewebsa tuning der Leber and der Niere. P. 274 OCHIAI, K. : Klinische Studien der Hydronephrose. 11. Mitteilung: Angeborene Hydronephrose. P. 291 End of Vol, 31, No. 4, October, 1941 THE JAPANESE JOURNAL OF UROLOGY Vol. 31, No. 5 November, 1941 CONTENTS AUTHOR ARTICLES YAMADA, M. : Statistische Beobachtungen über 542 Operationsfalle von Nierentuberkulose. I. Teil: Klinische Statistic, P. 321 TAKAHASHI, A. HARADA, G. ; Klinische Beobachtungen über die primar-cortikale Form der chronischen Nierentuberkulose. P. 346 TANAE, N. ; Experimentelle Untersuchung über die hodenallergle gegen Tuberkelbazillengift. F. 362 OCHIAI, K. : Klinische Studien der Hydronephrose, 111. Mitteilung: Kon- genitaler Hydroureter. P. 374 End of Vol. 31, No. 5, November, 1941 194 RESTRICTED M-AB ENCLOSURE ID), continued THE JAPANESE JOURNAL OF UROLOGY Vol. 31, No. 6 December, 1941 CONTENTS AUTHOR ARTICLES TANAE, N. : Experimentelle Untersuchung über die Hodenallergie gegen Tuberkelbazlllengift. IV. Mltteilung: Zyto orphologlsche Analyse von Allergischer Entzundung des Hodens. P. 401 YAMADA, M. : Statlstische Beobachtungen über $4 Operationsfalle von Nler- entuberkulcse. 11. Teil: Über die Prognose der Bleren- exstirpierten. P. 420 ITO, Y. : The Influence of male Sex hormone Upon the Morphological Changes of Endocrine Glands in Rabbits Fed on Lanolin mixed Diet. P. 439 TAGUCHI, Y. : Tiber die epidermoidalen Umwandlungen der Blasenchleimhaut bei chronischen Cystitiden. P, 470 End of Vol. 31, No. 6, December, 1941 THE JAPANESE JOURNAL OF UROLOGY Vol. 32, No. 1 January, 1942 CONTENTS AUTHOR ARTICLES OBASHI, T. TANAKU, K. : Über aen traumatischen Harnwegstein nach der Schussfraktur. P. 1 IWASHITA, K. : Zur Kasuistik der Luxation testis. P. 23 IMAIZUKI, K. : Cystometry: A preliminary report on the normal cystometro- gram. P. 41 ITO, Y. : The influence of male sex hormone upon the morphological changes of endocrine glands in rabbits fed on lanolin mixed diet. P. 96 End of Vol. 32, No. 1, January, 1942 195 M-AB RESTRICTED ENCLOSURE (D), continued THE JAPANESE JOURNAL OF UROLOGY Yol, 32, No. 2 February, 1942 CONTENTS AUTHOR ARTICLES : Über den Einfluss der Dekapsulation auf del betreffende niere und die Geschwisterniere. P, 147 NAMAHARA, K. KURAI, I. KITAMURA, G. YAMAMURA, T. IMAIZUMI, H. : Cystometry. Second report: On the intrinsic and external factors which influence the cystometrogram of the normal bladder. P. 171 HARADA, G. : Experimentelle Untersuchung über die Nlerentuberkulose, mit besonderer Beruckslchtigung des Verhaltens der Nierenrinde gegen Tuberkelbazillen. P. 197 End of Vol. 32, No. 2, February, 1942 THE JAPANESE JOURNAL OF UROLOGY Vol. 32, No. 3 February, 1942 CONTENTS AUTHOR ARTICLES YAMADA, M. : Statistische Beobachtung über 342 Operationsfalle von Nieren- tuberkulose. 111. Teil Rontgenuntersuchung der Lungen bei Nephrektomierten. P, 277 OKUNO, Y. ; Die Anwendung der Rontgenbestrahlung. Schwache Bestrahlung bei akuten Tripper. P, 297 IMAIZUMI, H. : Cystometry. Third report; Clinical cases. P, 301 IMAIZUMI, H. : Cystometry. Fourth report: On recording the intravesical pressure curve. P. 324 End of Yol. 32, No. 3, February, 1942 THE JAPANESE JOURNAL OF UROLOGY Vol. 32, No. 4 April, 1942 CONTENTS AUTHOR ARTICLES HAYASHI, R. : Studien über Sulfonamidpraparate. I, Mltteilung: Über die Resorption und Ausscheidung der Sulfonamide nach der elnmallgen Darreichung des Mittels. P. 391 196 RESTRICTED M-AB ENCLOSURE (D), continued MITSUSAWA, T. IT© , Y. : The influence of the male sex hormone on carbohydrate meta- holism. Part I: The variation of the blood sugar content in rabbits having abnormal testicular function, P, 417 NAKANO, I. : Ein Fall von pyelonephritischer Schrumpfniere. P, 433 End of Vol. 32, No, 4, April, 1942 THE JAPANESE JOURNAL OF UROLOGY Yol. 32, No. 5 May, 1942 CONTENTS AUTHOR ARTICLES HAYASHI, R. : Studien über Sulfonamidpraparate. 11, Mitteilung: Über die Resorption und die Ausscheldung von der Sulfonamidpraparaten nach der kontinuierlichen Darreichung. P. 391 End of Vol. 32, No. 3, May, 1942 THE JAPANESE JOURNAL OF UROLOGY Vol. 32, No. 6 June, 1942 CONTENTS AUTHOR ARTICLES SAKAI, S. : Über die Blasengeschwulste. 11. Teil, Zum Resultat der Blasengeschwulste. P. 537 HUZJI, N. : Über einen Operationsfall von subcutaner Nierenruptur und deren statistische Beobachtungen. P, 555 MITSUSAWA, T. ITO, Y. : The influence of the Male Sex Hormone on Carbohydrate meta- bolism. Part 11. The variation of the blood sugar content in rabbits having abnormal testicular function fed with fat- ty diet. P. 575 MITSUSAWA, T. ITO, Y. : The influence of the male Sex Hormone on Carbonhydrate meta- bolism. Part IV. The variation of the amount of liver glycogen in rabbits having abnormal testicular function. P. 575 TAKAHASHI, A. KUSUNOKI, T. : Fernresultate der Harnsteinkrankheit nach der Behandlung in der Urologischen Klinik der Kaiserlichen Universitat Tokyo in den letzten 13 Jahren. P, 581 End of Vol. 32, No. 6, June, 1942 197 M-AB RESTRICTED ENCLOSURE (DJ, continued THE JAPANESE JOURNAL OF UROLOGY Vol. 33, No. 1 July, 1942 CONTENTS AUTHOR ARTICLES HAN AI K. : Nierentuberkulose und Senkungsgescbwindigkeit des roten blut- ’ korperchens unter besonderer Berucksicbtigung der Operation. P. 10 : Über die Resorption und die Ausscbeidung verschiedener Sul- fonamidpraparate. P. 41 KANAGAMI, H. TAWARA, Y. KUSUNOKI, T. : Zur plastiscben Operation der Inkontinenz (Enuresis . P. 5' End of Vol. 33, No, 1. July, 1942 THE JAPANESE JOURNAL OF UROLOGY Vol. 33, No. 2 August, 1942 CONTENTS AUTHOR ARTICLES HOSODA T. : Experimentelle Untersucbungen über Blasentumor im Gefolge von Paratoluidin und m-Toluylendiamin (2-4 Diaminotoloen). I. Mitteilung. Versucne an Kanincben. P. 93 HAYASHI, R. : Studien über Sulfonamidpraparate. 111. Mitteilung: Über die Nebenerscheinungen, Leberfunktion und Harnreaktion. F. 107 KAGAYA J. WAKAMATSU", Y. ARAKI, G.’ : Über zwei Falle von maligner Hodengeschwulst, weicbe Gynako- mastie und andere positive Schwangerschstsreaktion des Harnes gezeigt batten. F, 121 IWASHITA, K. : Zur Anwendung der Tomographie fur intravenose Ureteropyelo- graphic im Kindeslater. P. 139 End of Vol. 33, No. 2, August, 1942 THE- JAPANESE JOURNAL OF UROLOGY Vol. 33, No. 3 September, 1942 CONTENTS AUTHOR ARTICLES NAKANO I. ; Studien über die mannliche Steriiitat. I. Mitteilung: Klinische Beobachtung. P. 179 198 RESTRICTED M-AE ENCLOSURE ID), continued TCKULI, I. NAKANC, I. KIMURA, K. YAZAWA, T. : Über die Urolithiasis. P. 212 End of Vol. 33, No. 3, September, 1942 THE JAPANESE JOURNAL OF UROLOGY Vol. 33, No. 4 October, 1942 CONTENTS AUTHOR ARTICLES AIKA, F. : Über die Elnlagerung der therapeutisch angewandten Silber- praparate in die Urethralschleimhaut bei Urethritis gonor- rhoica. P. 247 End of Vol. 33, No. 4, October, 1942 ‘THE JAPANESE JOURNAL OF UROLOGY Vol. 33, No. 5 November, 1942 CONTENTS AUTHOR ARTICLES SAKAI, S. : Über die Blasengeschvmlste. 11. Tell; Experimentelle Erzeugung von Blasengeschwulsten. P. 331 ICHIKAWA, T. TAMING, H. : Über ein grosses Embryoma testis. P. 363 TSUCHIYA, F. SHINDO, H'. OCHIAI, K. : Über die sogenante Purpura vesicae. P. 378 End of Vol. 33, No. 5, November, 1942 THE JAPANESE JOURNAL C? UROLOGY Vol. 33, No. 6 December, 1942 CONTENTS AUTHOR ARTICLES NAKANO, I. : Studien über die mannliche Sterilitat. 11. Mitteilung: Beitrag zur Epididymovasostomie. P. 427 199 M-AB RESTRICTED ENCLOSURE (D), continued OKUNO, Y. ; Über enen sekundar entstehenden Nierenbeckenstein zur Folge hatte. P. 458 OKOSHI, M. ; Drei Falle und statistische Beobachtungen in Japan von der zystischen Erwelterung des vesikalen Ureterendes (Uretero- cele). P. 462 End of Vol, 33, No* 8, December, 1942 THE JAPANESE JOURNAL OF UROLOGY Vol. 34, No. 1 January, 1943 CONTENTS AUTHOR ARTICLES ASAHARA, T. : Über die Einflusse von Gonadotropin auf das Wachstum der mannlichen Geschlechtsorgane des Meerschweinchens. P. 1 HORIO, H. HARADA, G. OKOSHI, M. Über die pyelograpbiscben Formveranderungen des oberen Harn- wegs bei dem dorsalen Ureterverlauf bei entwicklungsano- malie der unteren Hohlvene. P. 16 KUSUNOKI, T. : Über einen Fall von durch Dunndarmringplastik nach Scheele behandalter angeborener Kleinblase. P. 33 End of Vol. 34, No. 1, January, 1943 THE JAPANESE JOURNAL OF UROLOGY Vol. 34, No. 2 February, 1943 CONTENTS AUTHOR ARTICLES ASAWARA, T. : Experimentelle Studien über die Elnflusse der Endokrinen Organentrakte auf das Wachstum der mannlichen Geschlechts organe des Meerschweinchens. P, 6? TAKAHASHI, A. KOMATSU, K. ; Über die Curle-Therapie in Gebiete der Urologie, besonders Radiumemanations-behandlung Maligner Tumoren der Harnblase und Prostata. End of Vol, No. 2, February, 1943 200 RESTRICTED M-AB ENCLOSURE ID), continued THE JAPANESE JOURNAL OF UROLOGY Vol. 34, No. 3-4 April, 1943 CONTENTS AUTHOR ARTICLES KANAI, I. : The Tuberculin Reaction of the Bladder Wall. P. 159 KANUYARA, T. : Studien über die Antigene der Komplementbindunasreaktion bei der Gonorrhoe. P. 181 KAMAGAKI, K. : Über die Beziehungen zwischen der Konzentration im Blut bzw. im Urin und der teriziden Kraft des Blutserums bzw. des Ur- ins bei Verabreichung verschiedener Sulfonamidpraparate. P. 205 End of Vol. 34, No. 3-4, April, 1943 THE JAPANESE JOURNAL OF UROLOGY Vol. 34, No. 5 May, 1943 CONTENTS AUTHOR ARTICLES SATO, S. : Tiber die Ghemotherapie von Gonorrhoe mit aulfona midverbin- dung. (Mit Einschluss der Sulfonamid-Behandlung der Ureth- ritis simplex und Cystitis). P. 274 ISASHITA, I. : Primare Harnleitergeschwulst in Japan. P, 296 TONIKAWA, R. KITSURA, I. : Über einen Fall von Prostatasarcom. P. 306 End of Vol. 34, No. 5. May, 1943 THE JAPANESE JOURNAL OF UROLOGY Vol, 35, No. 3 September, 1943 CONTENTS AUTHOn ARTICLES TARAYASHI, F. ABE, B. ; Experimentelle Untersuchungen über die in das lebende Gewebe der hinteren Harnohre eindringende moglichkeit der Silber- praparate. P. 73 201 M-AB RESTRICTED ENCLOSURE ID), continued KAWAMURA, T. : Über die Resorption und die Ausscheldung von 3ulfonamidverb- indungen und ihre Verteilung im Korea. 111. Mitteilung: Übre die Verteilung des Sulfanilamides in Organismus und seine Resorption und Ausscheldung im Tlerversuch. P. 87 TAKAHASHI, A, KODATSU, B. KODA, Y. TODA, M. : Statistlsche beobachtungen von Blasentumoren an der Urologi- schen Klinik des Kaiserlichen Universitat Tokio. P. 129 End of Vol. 35, No. 3, September, 1943 THE JAPANESE JOURNAL OF UROLOGY Vol. 3s, No. 4 October, 1943 CONTENTS AUTHOR ARTICLES AKASAKA, H. : Klinische Beobachtungen der Nierengeschwulst. P. Is 3 ICHIKAWA, T. TAKAYASU, M. : Ein Fall von Anurie. P. 174 TAKAHASHI, A. HARADA,' G. : Ein kasuistischer Beitrag zur Klinik von primarem Karzinom des Harnleiters. P. 181 NAKANO, I. : Studien über die mannliche 111. Mitteilung; Endresultat. Anhang: Beitrag zur Schwellenwertfrage der befruchtungsfabigen Spermienzaiil. P. 196 End of Vol. 35, No. 4, October, 1943 THE JAPANESE JOURNAL OF UROLOGY Vbl. 35, No. 5“6 December, 1943 CONTENTS AUTHOR ARTICLES YANaGIHARA, A.: Über die intrakutane Reaktion bei Gonorrhea (1, Mitteilung). P. 223 ALAS AA, H. I Studlen über die Rontgenbilder der Nierengescnwulste, besond- ers über die Frage, ob jeder Tumor seir.en eigentumlichen pyelographischen Refund darstellt Oder nicht. P. 240 I CHULA'. r-., T, TAKAYASU, H. : Über die Nierenbeckenplastik bei Hydronephrosis. P. 29k 202 RESTRICTED M-AB ENCLOSURE ID), continued ICHIKAWA, T. KiMURA, K. : Über die Farbung der Tuberkelbazillen. P. 300 End of Vol. 35, No. 5-6, December, 1943 THE JAPANESE JOURNAL OF UROLOGY Vol. 35, No. 7-S August, 1943 CONTENTS AUTHOR ARTICLES 3i_o, S. : Über den Wirkungsmechanismus der Sulfonamidverbindungen und die Ursacbe des sog, Versagers bei der Gonorrhoebebandlung P. 1 End of Vol. 35, No. 7-8, August, 1943 HI JAPANESE JOURNAL OF UROLOGY Vol. 36, No. 1 January, 1944 CONTENTS AUTHOR ARTICLES IWASHITA, K. : Beitrag zur Kenntnis der pediatrisciien Urologie. 111. Mit teilung: Nierentuberkulose im Kindesalter unter besonderer Berucksichtigung ihrer Beziehung zu den anderen Tuberkulo- seherde. P. 1 3HINOHARA, M. ETC, K. : Klinische Beobachtung über das Verhaltnis der Hydronephrose zum Harnwegstein, besonder Ureterstein. P. 15 NAMIKI, J. NAKAMURA, M. KIZOUCHI, T. HONDA, H. HARADA, K. : Über eine neue Farbemethode der Niereninsel-Granule (Pol- kissen-Granule). P. 27 KOMATSU, K. : Experimentelle studien über die Radiumemanationsbehandlung der Blasentumeren. I, Mltteilung: Histologische Verande- rungen der mit Radonkapillaren eingespickten Blasenwand und Muskeln des Kaninchens. P. 31 ICHIKAWA, T. YA2AWA, T. ; Über retroperitoneale extrarenale Hypernephroide. P. 45 End of Vol. 36, No. 1, January, 1944 203 M-AB RESTRICTED ENCLOSURE (D), continued THE JAPANESE JOURNAL OF UROLOGY Vol, 36, No. 2 February, 1944 CONTENTS AUTHOR ARTICLES KOMATSUf K. : Experimentelle Studien über die RadiumemanatlonsbeJiandlung der Blasentumoren. 11. Mitteilung: Die bistologiscben Veranderungen der Blasentumoren mit engespickten Radongoldk- apillaren; Ein Beitrag zur Kenntnis der intratumoralen Bestrahlung mit Radonkapillaren. P, 79 ITAMI, N. : Über den Bau der inneren Uretiiralmundung. P. 91 KANEKO, C. HAMADA, G. ; Ein Fall von verkalkter und weiterhim verknocberter Hydrone- phrose. P. 101 ICHIKAWA, T. KIMURA, K. ; Über die Statistik der Nebenbodentuberkulose (Nebenhoden- tuberkulose, 1.) Studien der Urogenitaltuberkulose, 11, P. 107 End of Vol. 36, No, 2, February, 1944 THE JAPANESE JOURNAL OF UROLOGY Vol. 36, No. 3-4 April, 1944 CONTENTS AUTHOR ARTICLES AKIMA, T. KA, H. : Über eine neuen Nierenfunktionsprufung durch Sugiuron und der Reproduktion des Kontrastmittels aus der sugluronhalti- gen Harn. P. 129 TAKAHASHI, A. HORIO, H. OCHIAI, K. : Ein Fall von Blasenscheiteltumor—Urachustumor), P, 135 YAMADA, S. : Histamin in Niere. I, Mitteilung: Über die Schwankungen von Histaminmenge in Niere bei Traumen. P. 146 ICHIKAWA, T. KIMURA, K. : Über die Statistik der Prostatatuberkulose und Operation- sfalle (Prostatatuberkulose, 1.) Studien der Urogenitaltuber- kulose, 111. P. 16$ HANAI, K. : Bakteriologiscbe Untersuchungen bei der cbronischen Nieren- tuberkulose. P. 169 End of Vol, 36, No. 3-4, April, 1944 204 RESTRICTED M-AB ENCLOSURE ID), continued THE JAPANESE JOURNAL OF UROLOGY Vol. 36, No. 5 May, 1944 CONTENTS Table of Contents has been cut out. THE JAPANESE J-OURNAL OF UROLOGY Vol. 36, No. 6 June, 1944 CONTENTS AUTHOR ARTICLES YASUDA, T. : Zur Pathogenese der Harnsteinkrankheit. 11. Mltteilung: Über die Ursachlichen Beziehungen von Harnsteinbildung mit der experimentellen Hypervitamlnosis, D. P, 267 YASUDA, T. : Zur Pathogenese der Harnsteinkrankthelten.. 111, Mitteilung: Zur Frage der Harnsteinbilding in der Hypovitaminosis A. P. 278 HAMADA, N. : Rontgenologische Studien über die Bewegung des Samenleiters. P. 289 ITAMI, N. : Über den Schliessungsmechanismus der inneren Urethralmundung. P. 295 YAMADA, S. : Histamin in Niere. 111. Mitteilung: Der Histamingehalt in der Nlerenrinde und dem Nlerenmark bei Kaninchen. P. 302 NAGAI, H. : Über die Gefaseveranderungen bei der Nierentuberkulose. P. 305 SEKIMURA, T. : Die chemische Studien über die Harnsteine. P. 319 End of Vol. 36, No. 6, June, 1941 THE JAPANESE JOURNAL QF UROLOGY Vol. 36, No. 7-8 July, August, 1944 CONTENTS AUTHOR ARTICLES YASUDA, T. : Zur Pathogenese der Harnsteinkrankheiten. IV. Mitteilung: Harnsteinbildung und Zlrkulation der Nlere. P, 345 HAMADA, N. : Rontgenologische Studie über die Bewegung dee Samenleiters. Hite Mltteilung. P. 352 YAMADA, S. ; Histamln in Niere. IV. Mitteilung: Über die Schwankungen der Histaminmenge in Niere bei Rontgengestrablong. P. 355 End of Vol. 36, No. 7-8, July, August, 1944 205 M-AB RESTRICTED ENCLOSURE ID), continued THE JAPANESE JOURNAL OF UROLOGY Vol. 36, N0."9-10 October, 1944 CONTENTS AUTHOR ARTICLES YASUDA, T. : Zur Pathogenese Harnsteinkrankheiter. V. Mitteilung: Zur Pathologie der Nierenpahillen in der primare Nephrolithiasis. P. 393 SEKIMURA, T. : Studien über die Harnsteine. 111. Mlttellung: Rontgeno- logische Untersuchungen der Harnsteine. P. 407 ICHIKAWA, T. TAKAYASU, H. • Über die primare Blasentuberkulose. 1 Studien der Urogenit- altuberkulose. P. 417 OCHIAI, K. AKASAKA, Y. MAJIMA, K. : Dysurie durch die kleinen Prostatahypertrophie und die Blasehhalserkrankungen. P. 423 Vol. 36, No. 9-10, October, 1944 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXX, No. 1. January, 1941 CONTENTS AUTHOR ARTICLES KOBAYASHI, I. : Result of investigation of vitamin C in spinal liquid of the surgical cases in the Japanese Navy. FUKUDA, R. ; Study of finger-prints of Naval men. The First Chapter: Frequence of appearance of every type and index number of finger-prints. MIYATA, S. & KAYASHIMA, K. : Clinical observation of cases of scalding, OKAMURA',' T. ' : On the blood reaction of the tuberculous diseases. The First Chapter: Clinical observation of Weltman-Hayas’s serum coag- ulation band reaction compared with the reaction of sinking time of Red Blood Cells and Kopaozewskl’s serum lactogelific- ation. KISHIGAMI, S. TANAKA, Y. : On the para-type mannlte nonfermenting bacilli Isolated from dysentery patients who were stricken suddenly under prevail- ing conditions. DOSHO, H. : A cured case of Fibrom occuring in naso-pharyngeal cavity. TAKATORI, T. ; A case cured by operation of tumor in the spinal cavity caused by injury. End of Vol. XXX, No. 1, January, 1941 206 RESTRICTED M-AB ENCLOSURE ID), continued BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXX, too. 2. February, 1941 CONTENTS AUTHOR ARTICLES TAWARA, H. ; Experimental investigation of influence of low pressure and its sudden change upon body weight, number or quantity of red blood cells, and sinking time of red blood cells of rabbits. ABE, M. : Vitamin 81, excreted in urine of rabbits before and after ex- perimentally infected with tuberculous bacilli. OKAMURA, T. ; On the blood reaction of tuberculous diseases. The Second Chapter; On Laotogelification. DATE, T, : Study on mechanism of manifestation of Henry’s Melanofloc- culation. The First Chapter: Character of liquid used for reaction. End of Vol. XXX, No. 2, February, 1941 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION Vol. XXX, No. 3. March, 1941 CONTENTS AUTHOR ARTICLES KARIYA, K. YAMAMOTO, K. SHIBATANI, T. : Prophylaxis for Diphtheria among Naval men. TAWARA, H. : Experimental study on the influence of low pressure upon animals suffering from tuberculosis. (The Fi-rst Report). KONDO, Y. & MANABE, K. : A case of embryonal adenosarcom. YOKOKURA, S. & TAKAYAMA, K. : Study on the indirect Skiagraphy. (The Second Report). NAKAMURA, M. HAMADA, C. & ORIUCHI, 0. ; Report of autopsy on pellegra case IKEMOTO, K. & MIURA, T. Study on formation of abscesses in healthy rabbits OKABE, K. : A case of conjunctivitis due to diphtheria. End of Vol. XXX, No. 3, March, 1941 207 M-AB RESTRICTED ENCLOSURE ID), continued BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXX, No. 4. April, 1941 CONTENTS AUTHOR ARTICLES KAKISAKA, K. ; Study on wounds. The first chapter: Clinical Investigation * of haemo-thorax due to gunshot-wound of chest. SUDO, I. : Supplementary Report on Sohaltneuron-reflex. OKUYAMA, S. : Study on inflammation in the subcutaneous tissues due to Coc- cobacillus Foetidus Ozena isolated originally by Dr. Perez. The first chapter: Clinical investigation. MIYAZAKI, G. : Examination on the value of Chlite as a disinfectant. Ap- pendix: Disinfecting power of plum-juice. KISHIKAWA, H. : Study on an isolation of tuberculous bacilli by experiments on animals. Appendix: A case of tuberculous lymphadenitis from which tuberculous bacilli were isolated. FUKUDA, J. : Report of autopsy on Dr. Biermer’s anemia. End of Vol. XXX, No. 4, April, 1941 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXX, No. 5. May, 1941 CONTENTS AUTHOR ARTICLES KAKISAKA, K. : Study on wounds. The first chapter: Clinical Investigation of haemo-thorax due to gunshot-wound of chest. TABUGHI, G. : Symptoms in 6 appendicitis cases of fibroplastica. NAKAMURA, M. : Experimental investigation on the influence of vibration (rectilineal motion upon the internal ear). OKUYAMA, S. : Study on inflammation in subcutaneous tissues due to coco- bacillus faetidus ozena isolated by Dr. Perez. The second chapter: The character of isolated bacilli. ISHIHARA, I. : Result of load experiments of vitamin B1 in human body. MATSUDA, E. : Prophylaxis of mercury poisoning of employees handling mercury every day. End of Vol. XXX, No. 5, May, 1941 208 RESTRICTED M-AB ENCLOSURE (D), continued BUT.T/ETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXX, No. 6 June, 1941 CONTENTS AUTHOR ARTICLES KIYOHARA, S. : Experimental studies on adaptation of animals repeatedly ex- posed to high atmospheric pressure. The second report: On the phenomena of adaptation by training to high atmospheric pressure. KIYOHARA, S. : Experimental studies on the adaptation of animals repeatedly exposed to high atmospheric pressure. The first chapter: Influence of high atmospheric pressure on the blood carbon dioxide combining capacity, hemoglobin and blood cells of the untrained rabbit in high atmospheric pressure. FUKUDA, S. & USUDA, M. : Gunshot wounds in the abdomen. KAKISAKA, K. : Study on wounds. The first chapter: Clinical investigation of haemo-thorax due to gunshot wound of chest. ASHIHARA, S. : On Yoshida’s reaction and Brosamlen’s reaction of apparently healthy men whose sinking time of red blood cells accelerate continuously. SATO, S. : Eyesight of employees handling electric welding every day. End of Vol. XXX, No. 6, June, 1941 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXX, No. 7 July, 1941 CONTENTS AUTHOR ARTICLES NAKAUCHI, Y. : Investigation on wounds of urogenital organs caused by shoot- ing in recent campaign against China. TAKEI, n. : Investigation on kinds and distribution of anopheles in Hai- nan Island. MIYAGI, T. ; Study on growth of plasmodium prae-cox in the body organ of canary bird. TERAKADO, M. : A case of Kiyasthenia. MORI, T. : Cases of "Situs inversus viscerum" observed in brothers. : Study on the worth of Ogusol as a disinfectant HIGASHI, S. & lIOKA, 0. End of Vol. XXX, No. 7, July, 1941 209 M-AB RESTRICTED ENCLOSURE (D), continued BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXX, No. 8. August, 1941 CONTENTS AUTHOR ARTICLES TANIMURA, I. : Experimental investigation on the protective power and the effect by treatment with the derlvate of sulfonamid against the infection of meningo cocci. KONO, S. : Information on penetrative 'best wounds caused by shooting. SATO, K. : On color reaction of urine of malaria patients. (The second report). ENDO, T. : Study on the bacilli associated with gas gangrene isolated from dust in the naval ship. SHIINA, S. : Investigation on methods concerning vaccination. MUTO, T. ; Study on osteomyelitis caused by Coli bacilli. The first chapter: Clinical case. WATANABE, K. : Poisonous character of an industrial benzine and its influ- ence on the human body. MIYAO, I. TAKEI, H. HATORI, J. & NODA, H. : Investigation on the attack-rate of malaria of the inhabit- ants in Hai-nan Island. TAKEI, H. : Kinds and distribution of anopheles in Hai-nan Island. (Con- tinued ). End of Vol. XXX, No. 8, August, 1941 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXX, No. 9. September, 1941 CONTENTS AUTHOR ARTICLES ISHIHARA, I. : Experimental investigation on the influence of low atmos- pheric pressure upon the heart function of men who are in a deficient condition in vitamin. The first Chapter: Influ- ence of low atmospheric pressure upon heart function of men who are in a deficient in vitamin 81. MUTO, T. : Study on osteomyelitis caused by colon bacilli. DATE, T. : On the type of cholera vibrio isolated in middle and south China in 1939. 210 RESTRICTED M-AB ENCLOSURE (D). continued KIYOHARA, S. ; Experimental studies on adaptation of animals repeatedly ex- posed to high atmospheric pressure. The second report; On the phenomena of adaptation by training to high atmospheric pressure. MOTOYAMA, S, : Para-colon bacilli isolated from the patient showed severe symptoms like that of the shlga type bacillary dysentery. TANIMURA, I. : Experimental Investigation on the protective power and the effect by treatment with the derivate of sulfonamide against the influence of meningo cocci (continued). TAKEI, H. ; Investigation on the distribution of aedes aegypti in Hai- nan Island and its meaning observed from the point of epide- miology. HATTA, M. : A case of myelogenous leukaemia (promyelocytic) developed with the symptoms like angina in a pregnant patient who was suffering from nephritis. End of Vol. XXX, No. 9, September, 1941 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXX, No. 10. October, 1941 CONTENTS AUTHOR ARTICLES ONODA, H. ; Supplementary report on gas-gangrene. SATO, S. : Study on an occupational chronic poisoning of NO2 gas. SATO, N. : Four cases of infant appendicitis. FUJIMORI, B. : Investigation on the influence of high temperature upon wounded patients. NODA, K. : Investigation on the trouble of the hearing organ influenced by noise. The first report. MUTO, T. : Study on osteomyelitis caused by colon bacilli. The second chapter: The bacteriological experiment. (continued) ABE, I. : Study on the standardization to decide that the physical condition of employee who suffered tuberculous breast disease and improvement at present, is proper or not to commence their work. MURAKAMI, T. & CONDO, Y. : Result of Dick-test and preventive injection for scarlet fev- er practiced at the time when the scarlet fever prevailed in the Naval Engineering School in 1940. HATANO, K. : An interesting case of Filariasis. 211 M-AB RESTRICTED ENCLOSURE (D), continued MURAKAMI, T. A ISHIHARA, I. A case of colitis caused by a kind of Flagellate. OKURA, S. : A case of injury of cervical marrow caused by the spout (forming curved pipe like beak) of an oilcup. End of Vol. XXX, No. 10, October, 1941 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXX, No. 11 November, 1941 CONTENTS AUTHOR ARTICLES KAWAAI, S. : Supplementary opinion on the condition of patients and bacil- li carriers of para-typhoid A who had received the vaccine against this disease before they fell ill. TAKATORI, T. : Study on injury of the spinal cord. The first report. Sta- tistical and clinical investigation on injury of the spinal cord, ISHIHARA, I. ; Experimental investigation on the influence of low atmos- pheric pressure upon the heart function of men who are in a deficient condition in vitamin. The second chapter: Influ- ence of low atmospheric pressure upon heart function of men who are in a deficient in vitamin C, TANIMURA, I. : Study on Welchselbaum’s Diplococcus intracelluleris menin- gitidis. The first chapter: Isolating method and cultural medium. TOSHIBA, S. : Experiments of therapy of malaria during two years in the recent campaign against China. The first and second report. TAKEI, H. : Experimental study of the anopheles that grow in the sea water in Hainan Island. XONO, J. & lIOKA, 0. : Examination of the worth of Neo-xylon as an antiseptic sol- ution of spray and as a hand disinfectant. NAGAYAMA, C. & OKAMURA, T. : A case of osteomyelitis occured on the knee-cap. End of Vol. XXX, No. 11, November, 1941 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXX, No. 12. December, 1941 CONTENTS AUTHOR ARTICLES NOMA, M. : Supplementary opinion on the malaria prophylaxis. 212 RESTRICTED M-AB ENCLOSURE (D), continued KAWAAI, S. : 6 healed cases of para-typhoid A bacilli carrier. TANIMUHA, I. ; Study of Weichselbaum's Dlplococcus intracellularis menin- gitidis. The second chapter: Resistance of the bacilli. MURATA, S. : Statistical observation on the result of the reaction showed after the injection of B.C.G. KAKISAKI, K. 5 Two cases of poly-pseudo popliteal arterio-venous aneurysm. SUGIYAMA, S. & TAIRA, H. A case of eye wound caused by the propeller. HIROKAWA, H. & MURAKAMI, S. A case of exsudative diaphragmatic pleurisy that is diffi- cult to make diagnosis by the finding of X-Ray photograph. IMAI, T. : A simple apparatus which to be used to carry patients on board the ship. NODA, K. : Investigation on the trouble of the hearing organ Influenced by noise. The second report. End of Vol. XXX, No. 12, December, 1941 BULLETIN OF TEE NAVAL MEDICAL ASSOCIATION. Vol. XXXI, No. 1. January, 1942 CONTENTS AUTHOR ARTICLES IKEMOTO, K. : Experimental investigation of oligodynamic effect of metals in the sphere of surgery. The first chapter: Oligodynamic effect of metalic instrument used to join bones. TANAKA, T. : Eye troubles caused by the poisonous reaction of Sulfonami- de. MURAKAMI, S. HIROKAWA, H. : Observation of pulmonary tuberculosis of which symptoms were not noticed by patients themselves was found by the finding of X-Ray mass-photographing. KAKISAKA, K. : Study of war wounds. The second chapter; Clinical study on early second suture performed upon war wounds. HATTA, M. : Two cases of flbrom on tongue. ABE, I. : Statistical observation of Weil’s disease patients received treatment in Tsukiji Hospital of Tokyo municipality. HASHIMOTO, S. & SATO, T. : Investigation on an angle of upper abdomen of Naval men. SATO, S. : A case of degeneration of heart muscles observed calcified wheal of high grade found by autopsy. End of Vol. XXXI., No. 1, January, 1942 213 M-AB RESTRICTED ENCLOSURE ID), continued RTTT.T.F.TTN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXXI, No. 2. February, 1942 CONTENTS AUTHOR ARTICLES KAKISAKA, K. : Study of war wounds. The third chapter: Clinical investiga- tion of hematoma in muscles caused by gunshooting. ICHINOSEj H. ; Experimental investigation on the influence of low atmos- pheric pressure upon the oxydatlon in the body. The first chapter: On the oxydation quotient of the urine and the con- tent of the iodic acid in the blood of healthy mice and rat- bits and its relation with fodder taken. AKAKI, T. : Experimental Investigation of BCG. The first chapter: Viru- lence of BCG. TANIMURA, I. : Experimental study on the protective power and the effect of treatment with derivates of sulfonamide against the Infection of Weichselbaumfs diplocooous intracellularis meningitidis. SUZUKI, 0, : Increasing tendency of the patients of Flexner type dysentery occured in sudden prevalence. KONDO, A. : Relative annular scotoma observed in aviators. IKEMOTO, K. : Experimental investigation of oligodynamic effect of metals in the sphere of surgery. The second chapter: Oligodynamic effect of shell splinters. ITAZU, K. : A case of cartilagenous exostoma on the thighbone. ABJS, I. OKAMURA, T. & IKEDA, K. : Investigation on malaria of the Inhabitants (Mefu Li) of Buretsu Village in Hai-nan Island. End of Vol, XXXI, No, 2, February, 1942 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXXI, No. 3. March, 1942 CONTENTS AUTHOR ARTICLES KANAI, I. & MURAKAMI, R. : A case of stomach ulcus cancer accompanied, femoral vein trombosls of right side. YOKOKURA, S. & KCGO, M. : Prophylactic plan for the phthisis by the X-Ray indirect photographing. SATO, S. : Study on an occupational chronic poisoning of NO2 gas. (The second report). 214 RESTRICTED M-AB ENCLOSURE (D), continued HANAWA, H. : Statistical observation of gastric and duodenal ulcer and stomach cancer received surgical treatment. The first chapt- er: 89 cases of gastric and duodenal ulcer. SAKURAI, Y. : A case of big ozaenous appendicitis. AKAKI, T. : Experimental investigation of B.C.G. The second Chapter: Experiments on immunity. TAKEMURA, T. : An experience of the Inoculation of 8.C.G., administered nurses. ICHINOSE, H. ; Experimental investigation on the influence of low atmos- pheric pressure upon the oxydation in the body. The second chapter: Influence of low atmospheric pressure upon the oxy- dation quotient of the urine and the content of the iodic acid in the blood. End of Vol. XXXI, No. 3> March, 1942. BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXXI, No. 4. April, 1942 CONTENTS AUTHOR ARTICLES ABE, I. & FUJIWARA, H. : On paratyphosus A prevailed recently in the Japanese Navy. HANAWA, H. : Statistical observation of gastric and duodenal ulcer and stomach cancer received surgical treatment. The second chap- ter: 113 cases of stomach cancer. ICHINOSE, H. : Experimental investigation on the influence of low atmos- pheric pressure upon the oxydation in the body. The third chapter: Influence of accelerating agents of oxydation upon the oxydation quotient of the urine of mice under low atmos- pheric pressure. ICHINOSE, H. ; On the oxydation quotient of the urine in case of Liver dis- eases and its results of the examination of liver function by several methods. INOKUCHI, S. : Sciatica and its treatment by injection. KARIYA, K. : Excreting condition of cholera bacilli in the faeces of cholera patients and cholera bacillus carriers. KOMATSU, S. & TAMURA, T. : 3 cured cases of "Scalenus anticus syndrom" by operation. KOYAMA, H. ; A case of Gas Gangerene occured on board the war ship. End of Vol. XXXI, No. 4, April, 1942 215 M-AB RESTRICTED ENCLOSURE (D) * continued BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXXI, No. 5- May, 1942 CONTENTS AUTHOR ARTICLES ABE, I. : Study on S, Paratyphosus A Var. Durazzo. The first chapter: Biological and serological character. KIMURA, M. : Observation on the relative annular sectoma observed aviators. MATSUDA, F. ; Investigation concerning poisonous character of the Shale- oil. The second report. TAKAMURA, H. : Prognosis of the pleurisy patients in the Beppu Naval hosp- ital, especially clinical and statistical observation of the patients accompanied the tuberculous complication with above written pleurisy. SATO, S. : Study on an occupational chronic poisoning of NO2 gas. The third report. OKUYAMA, S. : 2 cured cases of costal tuberculosis and purulent costal osteomyelitis by operation. KOMATSU, S. : Bohler’s treatment for the fracture of the backbone caused by overpower. AKAKI, T. : Supplementary opinion on the cholera red reaction. End of Vol. XXXI, No. 5, May, 1942 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION Vol. XXXI, No. 6 June 15, 1942 CONTENTS AUTHOR ARTICLES MIYAO, I. : On the Prevention of Malaria in the Japanese Navy prepared for the Great East Asian War, especially on the Result of The Investigations on the Prevention of Malaria. TANIMURA, I. : Anaerobic Bacilli isolated from the earth. \ MATSUDA, F. : Investigation concerning poisonous Character of the Shale- oil. The second report. OKUYAMA, S. : Experimental Investigation on the Influence of low atmos- pheric Pressure upon the Content of the iodic Acid in the Blood Serum. SATO, S. ; Statistical Observation of round Ulcer of the Stomach found out by Autopsy in Tsukiji Hospital of Tokyo Municipality. 216 RESTRICTED M-AS ENCLOSURE tj), continued ABE, I. ; Study on Paratyphosus A Var. Durazzo. The second Chapter: biological Behaviour: ABE, I. : Study on Paratyphosus A Var. Durazzo. The third Chapter: Clinical and epidemiological Observation. IGUCHI, M. : A Case of malignant Syphilis, End of Vol, XXXI, No. 6, June 15, 1942 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION Vol. XXXI, No. 7 July 15, 1942 CONTENTS AUTHOR ARTICLES 3EKUZU, EIICHI: Note on the War Wounds for young Surgeons. TANAKA, YASUYCSHI : Supplementary Opinion of Light Sense. The first Chapter: Experimental Investigation on Light sense of the Patients who have each different Diseases. MASUOKA, SATORU : Supplementary Opinion on Gunshot wounds. (The first report) JCRI, TADO & OKADA, YUJI : Positive Rate of Tubercle Bacilli found by the Cultivation Method of Sputa among un-opened Patients suffering from Tuberculosis in the respiratory Organs. MIYAZAKI, GORO : Influence of the Excretors of Tubercle Bacilli in Sputa upon surrounding Persons who are living in Mass Formation on Board the War-ship, OKUYAMA, SHIN-ICHI : Study on an Inflammation in subcutaneous Tissues due to Coc- cobacillus Faetidus Ozena originally Isolated by Dr. Perez. The third Chapter: Experimental Investigation. HAYASS, SHOJI ; Study on the wandering circumscribed Edema found often in the Region along Yangte River in Middle China. ABE, ISAO : A Case of Mixed Infection of Amaeboid and bacillary Dysenteiy. YANAGAWA, TOSHIO, : and other five: Observation on Diphtheria prevailed in Mid- summer in Kure Marine Corps. End of Vol. XXXI, No. 7, July 15, 1942 217 M-AB RESTRICTED ENCLOSURE (D), continued BULLETIN OF THE NAVAL MEDICAL ASSOCIATION Vol» XXXI, No. 8 August 15, 1942 CONTENTS AUTHOR ARTICLES KAMBAYASHI, YOSHIHARU : Malaria Treatment in the front line. ONO, KENKICHI ; Study on a latent Strabismus observed among Aviators in an Air-port. TANAKA, TSUYOSHI : Supplementary Opinion of Light Sense. The first Chapter: Experimental Investigation on Light sense of the Patients who have each different diseases, (continued) MASUOKA, SATON : 10 Cases of the Fracture of an Anklebone. HOSHIO, KAWAKUBO & KANEO, KIKUCHI : Animal Experiments concerning on the poison in Poisonous Fishes in the South Seas and a Case of the Fish Poisoning. OKUYAMA, SHIN-ICHI : Study on an inflammation in subcutaneous tissues due to Coc- cobacillus Foetidus Ozena originally isolated by Dr. Perez. The third Chapter: Experimental Investigation, (continued) KARIYA, KAZUO : On Salmonella Paratyphi "east-africa" isolated from a seaman returned from China, found by am examination of faeces. : On Cholera Bacillus isolated from a patient contracted the disease in a certain ship entered in Saseho Naval Port. KARIYA, KAZUO SHIINA, SABRUO : New finding method of Malaria Plasmodium. KOBAYASHI, KATSURO : A case of Plasmochin (used for Malaria Treatment) Toxicosis observed peculiar symptoms which have never been reported in Literature. MIYATA, SATON & OKUYAMA, SHIN-ICHI : Report of a patient showed Gas-gangrenoid symptoms due to the mixed infection of a Bacillus resembling Perez's Coccobacil- lus and Coli Bacillus. End of Vol, XXXI, No. 8, August 15, 1942 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION Vol. XXXI, No. 9 September 15, 1942 CONTENTS AUTHOR ARTICLES Y. KODO : Recent tendency of research work on Tetanus. 218 RESTRICTED M-AB ENCLOSURE ID), continued I. NOBORU : Study on Fistula of abdominal wall. K, MASAYOSHI : Prognosis of so-called chronical Bronchitis in the Japanese Navy. S. KAZUHIKO : Clinical observation and finding of autopsy of Subtertian Malaria showed brain symptoms. M. TADAO ; Resistence of the red blood cells and influence of Tuberculin liquid by injection in Phthisis patients. T. TSUYOSHI : Supplementary opinion of light Sense of the patients who have each different diseases. M. SATORU : Simple sterilizer diviced for the purpose to sterilize surg- „ ical material for wound. K. KAZUO, and two others : Two cases of skin cancer originated from a scar due to heat wound. M. SATORU : Supplementary opinion on Gunshot wounds of bones. The second chapter. M. KANEO : A case of Poly-arthritis occured in the course of Bacillary Dysentery. 3. TOSHIO : Result of operation of Appendicitis, practiced in a submarine. H. TSUNEO : Clinical experiments on Neo-toxo?d of Staphylococcus. End of Vol. XXXI, No, 9, September 15, 1942 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION Vol. XXXI, No. 10 October, 1942 CONTENTS AUTHOR ARTICLES TANAKA, T. : Supplementary opinion of Light Sense. P. 805 IDOGAKI, T. : Studies on urobilinogen in the urine. P. 817 MURAKAMI, T. FUJIWARA, N. TOYAMA, K. HAYASHI, T. ; New culture media for early diagnosis of diphtheria. P. 830 MIURA, F. : Statistical observation of amoebae-dysentery patients who received treatment in the Sasebo Naval Hospital in this war. P. 833 MUTO, T. & HIRUKAWA : A case of cillindercell-sarcoma which produced metastasio in many internal organs, especially a large one in the heart, P. 842 219 M-AB RESTRICTED ENCLOSURE (D), continued KATO, M, : A case in which serious nervous symptoms appeared after the syringing of the sinus maxillaris. P. 846 KAUIMA, K. & YOSHINO, Y. : A case of tatanus following a wound on board ship. P. Bso OKAMURA, T. & KAUIMA, K. : Two cases of acute gangrenous appendicitis with hematuria. P. Bsl End of Vol. XXXI, No. 10, October 1942 BUTJETIN OF THE NAVAL MEDICAL ASSOCIATION Yol. XXXI, No. 11 November 1942 CONTENTS AUTHOR ARTICLES MATSUOKA, H. : Effect of the Ureshino Hot Springs on the Secretion of the Stomach. P. 874 TSUZUKI, N. : Crythrocyte sedimentation when using MgSO4 as an aati-coagul- tive medium. P, 883 SHIBATA, S. : The value of seawater for transfusion. P. 889 MASUOKA, S. : Supplementary opinions on gunshot wounds of bones. (The 3rd chapter) P. 89$ HIRUKAWA, Y. : Ozone therapy for spontaneous gangrene. P. 903 JTNNAI, H. & FUJIWAEA, N. KAKIHARA s S. ASHIHARA, S. : A case of tumor of the canda equina cured by operation P. 912 SUZUKI, K. : Hygienic conditions in Hainan Island. P. 915 End of Vol. XXXI, No. 11, November, 1942 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION Vol. XXXI, No. 12 December, 1942 CONTENTS AUTHOR ARTICLES MA.SUOKA, S. ; Supplementary opinions on gunshot wounds of bones. (The fourth chapter) P. 1088 MOTOYAMA, S. : Studies on the Schmitz's bacilli. (The first chapter) P. 1102 220 RESTRICTED M-AB ENCLOSURE (D), continued HIRUEAWA, Y. & SAITO, M. ; A case cured of a serious hemotoma of the pericardium, fol- lowing a slight trauma. P. 1115 INOUE, K. : On the discovery of active lung tuberculosis among the new sailors, by indirect x-ray photographs. KARIYA, K. & MEHARA, A : Paratyphoid B bacilli in the Sasebo epidemy. P. 1132 OHTSUKI, K. : Clinical and statistical observations on the epidemy of scar- let fever in Pure in 1939. P. 1147 SAWA, Y. : Fractures of the patella. P. 1156 ABE, I. : Two cases of idiosyncrasies against hydrochloric chlnine. End of Vol. XXXI, No. 12, December 1942 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION Vol. XXXII, No. 1 January, 1943 1. An Exhortion to Diligent Study. 2. Research on the Schmitz Bacillus {Shigella Ambigua). 3. Research on Twilight Vision. 4. A Comparative Study on the Effects of the Hot Springs at the Beppu Naval Hospital on the Wound Area, 5. Clinical Studies on Malaria Patients admitted to the Ureshino Naval Hosp- ital (Especially concerning one type of extra cellular pathogen). 6. Concerning Malaria Induced by Typhus Innoculatlons. 7. Data on Discovering the Kala Azar Pathogen and data on Marrow. 8. The Preparation of Facial Masks, particularly as related to Combat In- juries . 9. One Example of Primary Cancer of the Gall Bladder, 10. An Example of Scar Cancer of the Right Heel Bone, resembling a Tuberculous Ulcer. 11. rui Example of Typhoid Meningitis observed among Convalescent Typhoid Patients. 12. Regarding Extreme Ossification of the Right External Thigh Muscle and an Example of Ossifying Myositis of an external wound of the Medial Thigh Muscle. End of Vol. XXXII, No. 1, Jan, 1943 221 M-AB RESTRICTED EfICLOSHii (DJ, continues BULLETIN OF THE NAVAL MEDICAL ASS.TIATICN Vol. XXXII, No. 2 February, 1943 1. Research on Cerebral Electric l_rrents (Ft. 1. Basic Studies). 2. X-Ray studies on the Tubercular Tendencies of the Terminal Bronchial Lymphatics. 3. Research on the Schmitz Bacill-S Shigella Antigua, Pt. 3). 4. Clinical Observations of Typhoid Fever Patients aboard the Hospital Ship "Maru Maru". 5. Results of Focal Tests on evacuated Naval combat casualties, particularly as regards Amoebic Dysentery Pathogens. 6. Clinical observations of Epidemic Jaundice. 7. A case of Testicular Seminom. 8. An Example of the Excisior of an Encysted Tuner of the Pancreas. 9. One Example of Malignant Melons sarcoma in the Anus. 10. A clinical case in which both Sarcoma and Carcinoma occurred together. 11. Reports of the Medical Society. End of Vol. XXXI-, No. 2, Feb. 1943 BULLETIN OF THE NWAL MEDICAL - T l-TIE: Vol. XXXII, No. 3 March, 1943 1. Concerning Simple Chronic Ulcer of the Lower leg, occurring frequently in the Tropics. 2. Experimental research in the -effect of Lou iressure on Visural Respira- tion. 3. Clinical and latho-Histological study of Air-end iual Fecaliths. 4. A Statistical Observation of 1- serious cases of malaria which have given rise to Cerebral symptons. 3. Comparative study of (a) Variations in Electro-cardiograms and (b) Patho- Histological Cardiac Variations in the Human Being. 6. Effect of low pressure on Cc_l_r -hock foilßotation, especially . observation of cases of Pune t are d 7. New Ideas on the Treatment of Athlete’s Poet. 8. Concerning cultures of Cholera Bacilli isolated from cases which occurred aboard the Sumiyoshi Maru, ccjJLng from Hone long to Takao Harbor, ..arch. 1941. ~ 222 RESTRICTED M-AB ENCLOSURE ID), continued 9. Concerning Chronic Ulcers of the Lower Leg, or so-called "Chukoku" dis- ease on Hainan Island. 10. Insect bites as an important cause of Chronic Simple Ulcers, occurring in the Tropics. 11. An example of Epidemic Parotitic Encephalitis, 12. An example of Operation upon Hernia, caused by external injury. 13. An example of Pyothorox as the chief symptoms of Tumor of the Right inte- rior portion of the Heart. 14. An example of an Operation on Tuberculosis of the Stomach. End of Vol. XXXII, No. 3, March, 1943 BULLETIN OF NAVAL MEDICAL ASSOCIATION Vol. XXXII, No. 4 April, 1943 1. .-nti-Tuberculosis Measures by use of Indirect X-Ray Photography. 2. Research on the supplementary Aggutinative Reactions of the serum taken from Small Pox Patients and "Vaccination Normal" Subjects. 3. Experimental Research on the Influence of Low Pressure on Visceral Respir- ation. 4. Research of Techniques of Taking Lateral Sectioned X-Rays of the Skull. 5. Comparative study of (a) Variations in Electro-cardiograms and (b) Pattio- Histological Cardiac Variations in the Human Being. 6. Research on The Schmitz Bacillus (Shigella Ambigua) Pt. 4 Biological and Serological Aspects. 7. Cne example of Fibrogenous Appendicitis recognized among Naval Personnel. £. Three examples of Spasm of the Oesophagus and one example of Cancer of the Oesophageal Orifice of the Stomach, wrongly diagnosed as a case of the Above. 9. An Autopsical Example of Cellular Sarcoma, 10. Discovering Latent Vitamin C Deficiencies among Recruits, by Subcutaneous Pigment Reaction. End of Vol. XXXII, No. 4, April, 1943 223 M-AB RESTRICTED ENCLOSURE ID), continued BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. aXIX, No. 1. 15 January, 1540 CONTENTS AUTHOR ARTICLES SAKAI, T. : A clinical observation on the influence of pressure of eye- balls upon myopia. I ASHIBA, M. : Influence of the lack in the atmosphere small lon upon the Aschner’s Reaction and pulse. SUZUKI, 0. ; Biometrical studies on vertical movement of acromion in deep respiration. Part 11. Correlation and practical use. KISHIGAMI, S. : On Gaertner’s bacilli that were isolated from rats caught in the Kure Naval Port. YOSHIDA, H. : A practical application upon the diagnose of surgical tuber- culose as the result of cultivation of tuberculosis bacilli contained in gargle-water. TOKUDA, T. & TANAKA, T. : Ein Fall von einer über 20 jahren zuruckgebliebenen Zilie als fremdkorper im vorderkammer. End of Vol. XXIX, No. 1, January, 1940 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXIX, No. 2. February, 1940 CONTENTS AUTHOR ARTICLES MURAKAMI, S. : Two cases of so-called Tietze's suppurative white tumor, (Tumor albus). MURAKAMI, R. : A case of primary lung carcinoma ascertained by autopsy, but apt to be taken as plumonary phthisis by X-Ray picture of breast. HATAKEYAMA, I.: A case of temporary infiltration of the lung caused by a high grade tuberculous allergy. MATSUDA, F. : Cases of exostosis bursata. SUGIMOTO, T. : On the active movement of the blood picture and nuclear shift ascertained by examination of Japanese naval pilots engaged in the recent campaign against China. ODA, K. SHINDO, C. & NISHIHARA, H. : On types of cholera vibrio isolated in Shanghai in 1938. (First Report) 224 RESTRICTED M-AB ENCLOSURE (D), continued NAGAYAMA, C. HANAWA, T. & KURABANE, S. ; Relation between the sinking time of red blood cells and Syphilis. End of Vol. XXIX, No. 2, Feb. 1940 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXIX, No. 3. March, 1940 CONTENTS AUTHOR ARTICLES MURAKAMI, S. ; Study on compensative liquid for blood transfusion at the time of danger of death from acute hemorrhage. OKUYAMA, S. : On the effect of hot-spring on secondary symptoms of bone- fracture observed from skin temperature. NAGAYAMA, C. HANAWA, T. Sc KUROHANE, S. : Results of the combined examination on the early detection of tuberculous diseases in the respiratory organs. NAGATO, S. : Investigation concerning the infecting condition of Phthisis in naval ship life. NAKAMURA, M. : Über 2 falle von labyrinehntkrose. KONDC, Y. : Clinical and experimental study concerning treatment of Y type bacillary dysentery. End of Vol. XXIX, No. 3, March, 1940 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXIX, No. 4. April, 1940 CONTENTS AUTHOR ARTICLES MATSUO, D. : Study on respiratory phase of pleurisy patients by pneumo- graph. TAKAO, R. & KONDC, Y. Treating material for wounds prepared with sea-water, and fundamental study concerning the influence of sea-water on Incised wounds. SUZUKI, 0. : On the biometrical studies of diametrical thorax-expansibi- lity. MXYAGI, M. : Clinical observation of malaria prevailing in Boko Island {near Formosa) in 1937. 225 M-AB RESTRICTED ENCLOSURE (D), continued YOKOYAMA, G. : A case of blind bullet wound in the brain. KONO, S. : A case of necrose of costal cartilage complicated by serious gas gangrene and tetanus. IKEGAMI, K. & MANABE, K. : A case of pseudo peritoneal mixoma. End of Vol. XXIX, No. A, April 1940 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXIX, No. 5. May, 1940 CONTENTS AUTHOR ARTICLES KONLO, Y. : Experimental study on wounds caused by yellow phosphor. SUZUKI, 0. : On the biometrical studies of diametrical thorax-expansibi- lity. Part 11. The relation of the other measurement of thorax-expansibility. MORI, T. : Observation on pulmonal chalicosis of sand spray operators. SATO, K. : On color reaction of urine of malaria patients. NAKAMURA, M. : Ein fall von fibroblastensarkom mit atypischen riesenzellen in der kieferhohle. KOBAYASHI, I. ; A case of abnormal wedge-shaped vertebra that was diagnosed erroneously as bone fracture. End of Vol. XXIX, No. 5, May, 1940 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXIX, No. 6. June, 1940 CONTENTS AUTHOR ARTICLES TASHIRO, K. : Experimental studies on the susceptibility of rats fed with vitamin B deficient food to the paradysentery infection. (I. Report). TAKAMURA, K. : Clinical observation on the Frisch-Starlinger’s reaction ap- plied to tubucular patients. SAKAI, T. Sc ONE, I. : A case of so-called zinc-gas pneumonia. 226 RESTRICTED M-AB ENCLOSURE (D), continued MANABE, K. & KONDO, Y. : A case of stomach cancer perforating to the abdominal wall TERAKADO, M. Sc KIKUCHI, T. : A case of familial eosinophilia MASUOKA, S. : A healed case of intestinal and abdominal wall perforation caused by a swallowed foreign body. MATSUDA, F. : A healed case of agranulocytosis caused by the application of sulfanilamld and acridin dye-stuff. End of Vol. XXIX, No. 6, June 1940 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXIX, No. 7. July, 1940 CONTENTS AUTHOR ARTICLES SASAKI, K. ; Experimental studies on the Guttadiaphot Test of Naval men MIYAGI, M. : Clinical observation of malaria prevailing in Boko Island (near Formosa) in 1937. (The second Chapter). SEGAWA, T. : Graphical calculation of CO2 content in the air. KOBAYASHI, I. : Cases of spontaneous tibia fracture due to running. MURAKAMI, S. : A healed case of hydronephrosis caused*by retroperitoneal cystoma. NAKAMURA, M. : Über einen fall von primar in der Nahe der Schneidezahnen entwickelten gaumenkrebs. End of Vol. XXIX, No. 7, July 1940 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXIX, No. B, August, 1940 CONTENTS AUTHOR ARTICLES KIYOHARA, S. : An improved method for the micro-determination of blood carbon dioxide combining capacity. SHIINA, S. : A new wound-washing solution made by the author. 227 M-AB RESTRICTED ENCLOSURE ID), continued SHIBATA, T. MURAKAMI, S. TASHIRO, K. & SHINDO, C. : Bacteriological investigation of staphylococci isolated from wounds. TASHIRO, K. : Experimental studies on the susceptibility of rats fed vita- min B deficient food to the paradysentery infection. (II Report). MDRATA, S. : Supplementary studies on the clinical findings of tuberculosis of the kidney. TOKUYAMA, Y. : Two cases of suppurative osteomyelitis of clavicle. End of Vol. XXIX, No. 8, August, 1940 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXIX, No. 9. September, 1940 CONTENTS AUTHOR ARTICLES YOKOKURA, S. : Studies on the indirect Skiagraphy (I Report). HATAKEYAMA, I.: A case of mediastinal pleurisy complicated by an unusual disturbance in the circulation of blood. MIYAGI, M. : Clinical observation of malaria prevailing in Boko Island (near Formosa) in 1937. The third chapter: Treatment. MIURA, F. : Clinical observation on the patients of paratyphoid A admit ted in Sasebo Naval Hospital and the antigenic specificity of the strains isolated from the patients. HOSHINO, M. ABE, M. : A case of primary duodenal cancer KITAMURA, S. : A case of honeycomb lung. KOBAYASHI, I. ; A case of the detect of processus articularis vertebram. End of Vol. XXIX, No. 9, September 1940 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXIX, No. 10. “ October, 1940 CONTENTS AUTHOR ARTICLES HASHIMOTO, S. : Observation upon structure of body of naval men. KAYASHIMA, K. : Study on electrocardiogram. The third chapter. On elect- rocardiogram of the patients suffering from respiratory tuberculosis diseases, especially pleurisy. 228 RESTRICTED M-AB ENCLOSURE (D), continued NAGAYAMA, C. : On the ability to hang by the hands es decided by testing with the entrants to the Navy. NAGAOKI, M. & FUJINO, S. : A case of pseudo-femoral aneurysm arising from complications in wounds received during the present campaign against China. KISHGAMI, S. ; Observation upon the strains of cholera bacilli isolated from the patients in the town of Ondo in Hiroshima Rrefecture. HOSEINO, M. : Two healed cases of caries of the Huckle-bone. End of Vol. XXIX, No. 10, October, 1940 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Voi, mx, No. ii. November, 1940 CONTENTS AUTHOR ARTICLES ONO, K, : Untersuchung über die akkomodationszeit am auge des marin- efliegers. KAYASHIMA, K. : Die klinische und experimentelle erforschung über das elek- trokardiogramm. MIYAGI, T. : Result of after-experiments of malaria serum reaction and consideration for same. ISHIHAHA, I. : On excretive quantity of vitamin B, in urine of Beri-Beri patients. TAKATORI, T. : A case of chronic stiffness of vertebral joint. NAGAYAMA, C. & YOKOYAMA, G. : Ein fall von erschopfungsfraktur, KISHIKAWA, H. : A new isolating method of tuberculous bacilli from liquid in pleural, abdominal or cerebrosyinal cavity. (Preliminary Report). End of Vol. XXIX, No. 11, November, 1940 BULLETIN OF THE NAVAL MEDICAL ASSOCIATION. Vol. XXIX, No. 12. December, 1940 CONTENTS AUTHOR ARTICLES FUKUDA, 1941 THE JOURNAL OF BIOCHEMISTRY Volume 34 1941 CONTENTS AUTHOR ARTICLES TAKEUCHI, M. : Über den Abbau des Hi tidins, P, 1 YOSHIDA, S, ; Studien über die Phosphodiesterase. P. 23 FUNE, F. : Studien über Polysaccharide aus pathogenen Pllzen. I. Mit- teilung. P. 39 SAITO, H. : Über die Bakterienenzyme. I. Mitteilung. Beitrage zur Ken- ntnis der Asparaginase und der Aspartase der Bakterien. P. 49 CHANG, F. 5. : Über das Vitamin H. P. 71 232 RESTRICTED M-AB ENCLOSURE (D), continued CHANG, F. S. : Über die Niktoinsaure, P. 77 OKASAKI, K. : Über die Bildung der Reduktodehydrocholsaure {a-3-Oxy-7, 12- Diketocholansaure) aus Cbolsaure ImKarzinomgewebe. P. 83 KATAOZA, Y. : Über den Bildungsmechanlsmus der Cbeniodesoxycholsaure im Crganismus, I, Über das SchicKsal der Chenodesoxycbolsaure im Leberbrei von Meerschweinchen. P. 87 11. Über die biocbemiscbe Reduktion der Dehydrochenodesoxycholsaure im Lebersciinitt des Meerscbweinchens und Huhns, P. 93 111. Über das Scbicksal der Chenodesoxycholsaure ia Krotenorgan- ismus. F. 99 SAITO, H. : Über die Bakterienenzyme. 11. Mitteilung. Über die Gart- ner- Amid a sen. P. 103 KUBOTA, T. : The reactions of sugars with amino acids under mild condi- tions. F. 119 KOBAYASHI, T. : Biochemical studies on Carbohydrates. Lilli, Blood group a substance from pig pastrie mucus. P. 143 KOBAYASHI, T. OHARA., T. SHINOKAWA, T. YASUCKA, T. ADATA, M. : Biochemical studies on carbohydrates. LXIV, Group specific substances in human urine. P. 149 H ALIAS AT 0, Y. AKAKURA, K. : Biochemical studies on carbohydrates. LXV. An improvement of the Masamune-Nagazuml method for estimation of hexosamine in protein hydrolytes. P. 159 SUZUKI, H. : Biochemical Studies on carbohydrates. LXVT. Separation of the prosthetic group of seromucold. P. 167 KTUTOKU, T. : Die biochemische Untersuchung der Leberfunktion in den tokologischen und gynakologischen Gebieten. I. Abtellung. Tiber die gesunden Nichtswangeren und Schwangeren. Page 173 11. Abteilung. Tiber die schwangeren Kaninchen mit exper- imenteller Leberschadigung. F, 193 SAITC, K. : Über die Bakterienenzyme. 111. Ivlitteilung. Über die Gartner-Froteasen. P. 213 SAIT'O, H. : Über die Proteasen und Amidasen des Llycobacterium Phlei (Timotheebakterien). P. 223 FUJIMURA, S. : Studies on the organ specificity. P. 233. FUKE, F. : Gtudien über Polysaccharide aus pathogenen Pilzen. 11. Mit- teilung. Über die Gartner-Proteasen. P. 213 FUKE, F. : Studien über Polysaccharide aus pathogenen Filzen, 11. Mit- teilung. P. 251 KOCHI, D. : Über die Kanincbenarginase. I. IJitteilung. Dber die Gewe- bearinase nacb der Metallsalzinjektion unter besonderer Berucksichtigung der Blutarginase (Arglnasarnie). P, 257 233 M-AB RESTRICTED ENCLOSURE (D), continued 11, Mitteilung. Über das Auftreten der Blutarginase (Argin- asamie) nach der Metallsalzlnjektion. P. 281 111. Mit- teilung. Tiber das Verhalten des Harnstoffs in Blut und Harn des Kaninchens nach der Mangansulfatinjektion. P. 295 IV. Mitteilung, Über die Arginasewirkung bei der Urany- Initrat und Cantharidinvergiftung. P. 307 FUJITA, A. DOI, K. KAWACHI, S. : Über die Hydrolyse des veresterten Aneurins durch Gewebe- phosphatase. (Bemerkung über die Bestimmung des freien Anurins im Gewebe) P. 315 ONISHI, T. : Tiber die Protease-, Amldas'b- und Esterase-wirkung der saur- efesten Bakterien. P. 325 KAZAMA, T. : Bemerkungen zu der Arbeit, "Über die Hydrolyse der Acylpep- tlden" Enzymologia 9» 356 (1941) von Moritsune Nishlhlra, P. 335 NISHIHIRA, M. ; Antwort auf obige Bemerkungen von T, Kazama. P. 337 MIZUNO, H. : Untersuchungen über den partiellen Abbau der Proteine, V. Mitteilung. Partielle Spaltung der Gelatine durch aufein- anderfolgende Anwendung von Natronlauge und Salzsaure. P. 339 KURANARI, Y. : A method of determining sucrose content in the blood. P. 371 TAEEDA, Y. WATANABE, S. : Das gereiningte Tuberkulln-Protein aus Altfcuberkulin. P. 385 TAKI, M. : Über die Aktivierung der Arginase. P. 399 AJISAKA, M. : Isolierung des Kryotoxanthins aus Schalen von Ponkan (Citrus pooensis Hort) sowie aus Fruchthaut von Togarasi (Capsicus annuum L.) P. 421 TOSHIBA, T. FUKUYAMA, S. : Tiber die im Tierkorper stattfindenden Veranderungen as N substituierten Aminosauren. 7. Mitteilung: Tiber die Demethylase I. P. 429 KTJSDNOKI, M. ; Studien über die Zahnsteinbildung (II). P. 441 End of Volume 34, 1941 THE JOURNAL OF BIOCHEMISTRY Volume 35 1942 CONTENTS AUTHOR ARTICLES STJEYCSHI, Y. TOYAMA, K. ; Tiber die Zuckerbildung aus Fett im Tierkorper. I. Mlttel- lung. Tiber Leberglykogen bei kohlehydratfreier Fettdiat. P. 1 234 RESTRICTED M-AB ENCLOSURE ID), continued TOYAMA, K. : Über die Zuckerbildung aus Fett im Tierkorper. 11. Kit- teilung. Über die Bp-Avitaminose bei kohlehydratfreler Fet- tdiat. P. 9 FUJIIvTURA, S. : Further studies on the organ specificity. P. 25 HORIKOSHI, K. : Studien über die Carbodydrase. 5- Mitteilung. Über B- Glukosidase und B-Galaktosidase von Takaund Emulsln-Typus. P. 39 KOYANAGI, J, : Über die Ablagerung des Chaulmoograols in den Organen. P. 61 FUKASAEO, T. : Studium über das Blutphosphatid. I. Mitteilung. Über die Beziehung zwischen den Serumphosphatiden und den Fraktionen des Serumeiweisses. P. 67 FUJITA, A. MATSUKAWA, D. Bemerkungen über die kolorimetrische Bestimmung des Vitamin B]_ in tierischen und pflanzlichen Geweben. P. 79 FUJITA, A. MATSUKAY/A, D. : Über die Verteilung des Vitamin Bp in tierischen und pflanz- lichen Geweben. I. P. 89 UTSUNOMIYA, T.: Studies on carboxypeptidase. P. 103 AJISAKA, M. : Über die Bestiramung des Provitamin A. 11. Bestimmung des Kryptoxanthins. P. 119 KOYANAGI, I. : Über den Stoffwechsel der Tiere bei der Ciiaulmoograol in jek- -4 tion. Über den Einfluss des Chaulmoograols auf die Phosphor- verbindungen im Blute. P. 133 IWAKI, K. : Über das Schicksal der Trioxy-bufosterocholensaure im Meer- schweinchenorganismus. P. 139 IWAKI, K. : Über das Schicksal der Trioxy-isosterocholensaure im Kanin- chenorganismus. P. 149 KANEMITSU, T. : Über die Alligatorschildkrotengalle. 111. Über die chem- ische Konstitution des Trioxy-sterocholansaurelaktion. P. 155 IV. Über den abbau des Trioxy-sterocholansaure-laktons bis zur Bisnorcholsaure. P. 173 SEI, Y. : Über racemisciie Isomere des Leucyl-isoserins. P. 187 OZAWA, R. ; Über den St of fwechsel des mit Ciiaulmoograol injizierten Tieres. Über ihre Wirkung auf den Blutzucker des Kaninchens. P. 193 KANAZAWA, K. : Über den Stoffwechsel des mit Ciiaulmoograol injizierten Tieres. Über ihre Wirkung auf die Menge der Fraktionen des Eiweisses im Blutplasma des Kaninchens. P. 203 AtyANO, M. : Über den Stoffwechsel bei niedriger Temperatur. I. Mit- teilung: Über den Zusammenhang zwischen niedriger Temperatur und dem Serumkephalin. P. 219 IWAKI, K. : Über das Schicksal des Pentaoxy-bufostans im Meerschweinchen- organismus, P. 225 235 M-AB RESTRICTED ENCLOSURE (D), continued SUGANAMI, T. YAMASAKI, K. : Über die Alligatorschildkrotengalle 11. Trioxystero und Trioxy-isostero-cholansaurekalton. P. 233 SAITO, H. : Studies on tyrosinase. VII. The action of the potatoe tyrosinase on trihydric phenols. P. 243 FUKE, F, : Studien über Polysaccharide aus pathogenen Pilzen. 111. Mitteilung. P. 259 IV. Mittellung. P, 263 AJISAKA, M. NUMATA, I. DOI, K. OKUBO, S. : Über die Anderung des Gehalts an Vitamin A, Bi, B2 und C in Gemusen und Obst wahrend der Aufbewahrung. P. 271 TOKUNAGA, K. : Beitrag zur Kenntnis der Takadiastase. P» 281 KUGA, T. : Über die katalytische Decarboxylierung der B-Ketocarbonsaure. P. 293 FUJIMURA, S. : Studies on the heterogenetic antigen. 111. Studies on the antibody producing substance. P. 307 OKUGAWA, Y. : Experimentelle Untersuchungen über die Beizehungen zwlschen B-Vitamin und Kohlehydratstoffwechsel, P, 325 ISHIMOTO, K. : Über einen Inhibitor der Glyoxalese. P. 351 SHIBUYA, S„ : Biochemical studies on guanidine-bodies. I. Reaction be- tween ammonia and amino compound in the presence of charcoal. P. 379 YAMASAKI, S. : Biochemical studies on the rice of Chosen. 111. On the fat of the rice-bran. P. 393 KANEMITSU, T. : Über eine isomere Cholsaure, Hetercholsaure aus der Alligat- orschildkrotengalle. P. 409 KANEMITSU, T. : Bildung von a- und B-3-Oxy-7-ketocholansaure aus Dehydro- chenodesoxycholsaure im Krotenorganismus, P. 413 DOI, K. : Über die Verteilung des Vitamin Bi in tierischen und pflan- zlichen Geweben. 11, 111. P. 419-431 End of Volume 35, 1941 THE JOURNAL OF BIOCHEMISTRY Volume 36 1944 C PITT ENTS AUTHOR ARTICLES AKA, K. ; Über die Verwertung der Fettsauren in der Leber und den Musk- el beim Hungern, P, 1 MATSUBARA, K. t Über den Gehalt der Gewebe an verschledenen ungestattigten Fattsauren im Fett und Phosphatid bei Normal- sonle Fettdist. P. 17 236 RESTRICTED M-AB ENCLOSURE ID), continued OYAMADA, Y. : Die Mlkrobestimmungsmethode des Histidins im Harn, P. 43 KATAOKA, Y. : Über den Bildungsmechanismug der Chenodesoxycholsaure im Organismus. IV. Über das Schicksal der 3-oxy -Cholensaure in Kaninchen- und Meerschweinchenorganismus. P. 55 V. • Über das chicksal der 3.7-Dioxy-12-ketocholarsaure im Kaninchen- organismus. P. 6l OKASAKI, Y. : Über die Gallensauren von Wassersalamandern. I. Über die Gallensaure und Steroide in der Galle des Wassersalamanders (Diemyctylus Pyrrhoaaster). P. 65 11. Über die Synthase von Homocholan C 25 und Isuohomocholen aus Tetraoxylso- homocholan aus der Galle von Wassersalamandern. P. 77 OKASAKI, Y. : Über die Extraktivstoffe der Leber von Wassersalamandern (Die myctylus phrrhoaster) im winterschlaf. P, 85 SUGAI, K. : Studies on protease. VI. The effect of the addition of various salts on the triatic activity, P, 95 AJISANA, J, : Über die Verteilung des Kryptoxanthins in pflanzlicben Ge- weben, I. P. 101 NOGUCHI, S. : Über die lezitoinspaltenden Fermente. P. 113 NAITO, Y. : Biochemical studies on d-ribose, with special reference to the mechanism of absorbtion of sugars from intestinal tract. P. 131 KANAMIRU, T. IWAKI, K. : Über den Bildungsmechanismus der Chenodesoxycholsaure im Organismus. VI, Über das Schicksal der 3«7-Droxy-12-Keto- cholansaure sowle der 3.7.12-Triketocholansaure im Meersch- weinchenorganismus, P, 163 MATSUMOTO, K. : Synthese der B-3-aDloxy-allocholansaure und der B-3-a 12 Dioxy-cholansaure. P. 173 MATSUMOTO, K. : Über die Synthese der B-Allodesoxycholsaure aus Cholsaure, P. 183 IWAKAWA, Y. : Studies on the pasteur reaction in muscle. P. 191 OYAMADA, Y. ; Der enzymatische Abbau der Histidins. P. 227 NAKAMURA, B. : Über die Spezifltat der Arginase, P. 243 A JIB AKA, M. ; Über die Vertelllung des Krypthxanthins in pflanzlicben Ge- weben. 11, P. 263 KANDO, K. : Über die Konstitution des Olhigers, reines N-Haltigen Extr- aktivstoffe der Scblangenmuskel. P. 265 MOTOKURA, S. : Über eine garbeschleunigende Wirkung der Zahnpulpa. P. 277 MOTOKURA, S. ; Üben den Elnfluss des Carnosins und Orhldins auf die alko- bolischen Garung, P. 283 TANAKA, H, : Chemie der Meerschlldkroten. I. Über die N-naltigen Extr- aktivstoffe der Muskeln von Meerschlldkroten. P. 289 ll* Über die Fermente der Meerschlldkrotenorgans. 111, Chem- 237 M-AB RESTRICTED ENCLOSURE ID), continued ische Untersuchungen des Hams von Chelonia japonica Thumb, P. 289-313 MARU3AIIA, Y. : Chemische Untersuchungen der Schaerlen. (Misgurnus Anguil- licandatus Cantor). P. 317 I.'IARUSAIKA, Y. : Chemie des L/lalariaharns. P. 329 IMAMURA, K. : Über das Auf tret en der Milchsaure 1m Harn nach dem Kardia- zolkrampf. P. 335 TANITA, M. TANAKA, T. : Über den respiratonlschen Stoffwechsel beim Embryo der Rep- tilien. P. 337 TAMITA, M. TANADA, T. : Verwirkllchung der phytochemischen Reduktion von Trimethyl- aminoxyd. P, 345 YOSHIDA, T. FUKUYAMA, S. : Über die im Tierkorper stattfindenden Veranderungen der an N substituierten Aminosauren. 8. Mitteilung: Über die Demethylase 11. Ihre Verteilung. P. 349 YOSHIDA, T. : 9. Mitteilung: Über die Demethylase 111. Ihre Eigen- schaften und Komponenten, P. 355 SHINKAI, K. : Über die Zuckerbilder der Haut bei normalen und pathologis- chen Stoffwechsel. P, 369 SAKAI, T. : Über die Geweb proteolyse. 11. Mitteilung: Über die ereptasefreie Katheptase-Wirkung und die kathe tische Acyl- dlpeptidase-Wlrkung. P. 383 SUZUKI, H. : Biochemical studies on carbohydrates. DOCK, On neutral polysaccharides of glycoproteins, A supplementary note of the LIX and LXVI information. P. 395 KOBAYASHI, T. : studies on carbohydrates. L2QDCI, Chondrosin. i'hrid Report: On so-called Chondridin. P. 399 TAKEDA, Y. DATA, T. SATO, N. : Studien über des Endotoxin von Calmonella Typhl, I. Mit- teilung: Die Isolierung der antigenen und hoch toxischen Substanz aus Salmonella typhi, P, 407 TAKEDA, Y. OHTA, T. SEN, Y. ; Studien über das Endotoxin von Pacillus Oysenteriae Shiga, I. Mitteilung: Die Isollerung der toslxchen und antigenen Substanz von Bacillus dysanteriae Shiga, P, 419 SAKAI, T. : Dber die Gewebeproteolyse. 111. Mitteilung: Über die katheptische Bestorspaltung. P. 427 IV. Mitteilung: Unterschelduiig der Katheptischen Peptenasewirkung von der proteinasewirkung. P, 443 KAWAKURADA, F.: Über die Aktivierung der tryptischen Wlrkung des Pankreae- saftea des Hundes. I, Mitteilung: Saure-und Saure-Cystein- Aktivierung der tryptischen Wlrkung des Pankreassaftes. P. II. Mitteilung: Beitrage zur Kenntnis der Kinase- Aktivierung der tryptischen Wlrkung des Pankreassaftes. P. 485 111. Mitteilung: Die Wlrkung des Darmsaftes auf die Aktivierung der tryptischen Wlrkung des Pankreassaftes. P. 509 IV, Mitteilung: Die Wlrkung der Gewebemazeration auf die Aktivierung des Pankreassaftes. P. 521 238 RESTRICTED M-AB ENCLOSURE (D), continued TAKEDA, Y. OTA, T. lUCHI, I : Versuch zum Ozonabbau des Leprotains. P, 535 lUCHI, I. : Über das Verhalten verschiedener Kohlenhydrate der Organs und Gewebe im Hungerzustand und wahrend des Winterschlafs. P. 539 End of Volume 36, 1944 ACTA SEROLOGICA ET IMMUNOLOGICA Vol. 1, No. 1 June, 1940 CONTENTS AUTHOR ARTICLES KAGAYA, Y. : Über das Eislersche heterogenetische Menschenblutantigen, P. 1 FURUHATA, T. : Über die typenspezifische Prazipitation and die neuen Typen- substanzen, T, Al, 81, Cl, und 01 in Sekreten. P. 15 KASUYA, I. : Recent Advances in the Investigation on the Active Principles of Tuberculin. P, 2$ SHIGA, K. : Ehrlich’s Studien über das Toxin und Antitoxin. Diskussion zwischen dem Biologen und Physikochemiker. P. 41 IMAI, B. : Studies on the Relation between the Nerve and Anaphylaxis. P. 71 IKUTA, Y. : Experimental Anaphylaxis Induced by Picric Acid. P. 103 OTA, T. : Critical Observation on the Preservation of Complement Serum for a Long Period of Time. P. 123 End of Vol. 1, No. 1, June, 1940 ACTA SEROLOGICA ET IMMUNOLOGICA Vol. 1, No. 2 August, 1940 CONTENTS AUTHOR ARTICLES : List of Serological and Immunological Papers Published in Japan During 1939. P. 193 : From: ’’Third International Congress for Microbiology, New York, Report of Proceedings, 1939*" P. 263 End of Vol. 1, No. 2, August, 1940 239 M-AB RESTRICTED ENCLOSURE ID), continued ACTA SEROLOGICA ET IMMUNOLOGICA Vol. 1, No. 3 October, 1940 CONTENTS AUTHOR ARTICLES NAKAMURA, K, ; Neue Anschauung über die Entstehung des anaphylactischen Schocks, insbesondere die Bedeutung von Acetylcholln in der Anaphylaxie. P. 318 OGATA, T. ; Studies on the Precipitation Reaction. V. On the Symbols for the Designation of the Antigen and Antibody Titers. P. 335 OGATA, T. et al. ; Studies on the Precipitation Reaction. VI. On the exactness of the Antigen and Antibody Titers. P. 339 SHIMADA, M. : Studies on the Precipitation Reaction, VII. Syntheses and Reanalysis of the Forms of "Field of Reaction". P. 343 IMIO, B, : On the Ability of Organ Extracts to Induce Shwartzman Pheno- menon. P. 359 MAKIHATA, S. : Experimental Anaphylaxis Induced by Laxatol. P. 377 MURASUGI, T. ; Über die Technik der "verbesserten" Flockungszahlreaktion. P. 385 End of Vol. 1, No. 3, October, 1940 ACTA SEROLOGICA ET IMMUNOLOGICA Vol. 1, No. 4 December, 1940 CONTENTS AUTHOR ARTICLES IMIO, B, : Alleviating Effect of Evipan-Natrium upon Anaphylactic Re- actions. P. 453 MAKIHATA, S. : On the Influence of Hypertonic Sugar Solutions upon Anaphy- latic Reactions. P, 461 UMEZAWA, H. : On the Henry Reaction. 11. The Reaction between Malaria Sera and Various Sols. P. 479 DMEZiAWA, H. : On the Henry Reaction. 111. A Comparison of Mastix Sol Re- action and Melanoflocculation for Malaria Diagnosis. P. 485 NAKAGAWA, Y. : Studies on the Components of Complement. Part I. Haemolytic Complement Action of a few Proteins other than Serum. P. 499 240 RESTRICTED M-AB ENCLOSURE (D), continued NAKAGAWA, Y. : Studies on the Compenents of Complement. Part 11. Studies on the Components of Haemolytic Complement by Means of the Ultrafiltration. P, 521 AKIMOTO, S. : A. Contribution to the Inhibitory Effect (Gross-Ogata) of the Shwartzman Phenomenon. P. 531 OKABAYASHI, A.; Experimentelle Erzeugung von Karditls vom Pheumatyp durch Streptokokkeninfekt on der Nasennebenhohle bei Kaninchen. P. 539 OKABAYASHI, A.: Experimentelle Studien über die Fokalinfektion. P. 547 OSUKA, K. : Experimentslie Untersuchungen über die Anaphylaxis. Insbes- ondere über die Bedeutung von Acetylcholin in der Anaphylaxie. P. 565 FUKUDA, T. RIN, T. K. OGATA, T. : Treatment of Erysipelas by Infection of the Shwartzman Fil- trate. P. 619 End of Vol. 1, No. 4, December, 1940 ACTA SEROLOGICA ET IMMUNOLOGICA Vol. 2, No. 1 March, 1941 CONTENTS AUTHOR ARTICLES TAKITA, I. : The influence of Physical Conditions of Culture Media upon Biological Properties and Toxin-Prodnotion of Bacteria. P. 1 OGATA, T. SHIMADA, M. : Studies on the Precipitation Reaction. VIII. Fundamental Observations on Cross-Reaction. P. 17 OGATA, T. SHIMADA, M. : Studies on the Precipitation Reaction. IX. Some observa- tions of Precipitation Reaction with Serum Obtained by Anti- gen Adsorbed by Aluminum Hydroxide. P. 31 SHIMADA, M. : Studies on the Precipitation Reaction. X. Studies on the Essential Feature of Specificity of the Precipitation Reac- tion of Sera. P. 35 KATO, K. OTA, N. OKADA, Y. : Anaphylactic Reactions of the Pigeon (I). P. 89 AOKI, M. : Relation of Pollens to Seeds and Bulb as Shown by Anaphylactic Reactions. P. 97 NAKAGAWA, Y. : Studies on the Components of Complements, Part VIII, Dif- ference between Haemolytic and Bacteriolytic Complements, P, 10? 241 M-AB RESTRICTED ENCLOSURE (DJ, continued BANDO, Y. : Über fluchtiges Toxin, entstanden durch Destination von Nahrbouillon zusammen mit den darin gezuchteten Tuberkel- bazillen. P, 117 End of Vol. 2, No. 1, March, 1941 ACTA SEROLOGICA ET IMMUNOLOGICA Vol. 2, No. 3 September, 1941 CONTENTS AUTHOR ARTICLES HIRANO, N. : On the Immunity of the New-Born, P. 295 YAOI, K. : Recent Advances in the Cow-Pox Vaccine Production. P. 307 SHIGA, K. : On the Pure Culture Vaccine Virus. P. 323 MIKAMI, Y. : Die Antikorper bei Kaltblutern, Über die Anwesenheit des immunisierten Antigens bei Kaltblutern. P. 333 SAKURAYAMA, Y.: Experimental Anaphylaxis Induced by Chromium Compounds. P. 351 IGUCHI, T. : Anamnestic Reaction of the Kyersensitive Skin Reaction. P. 361 TASHIRO, K. : Über die Prazipitlnogenitat koagulierten Serumeiweisses. P, 365 NAKAGAWA, Y. ; Studies on the Analysis of Antibodies. Part I, Studies by the Absorption Tests. P. 373 1 NAKAGAWA, Y. : Studies on the Analysis of Antibodies. Part 11, Studies by the Method of Ultrafiltration. P. 363 End of Vol. 2, No. 2, June, 1941 ACTA SERCLOGICA ET IMOJNOLOGICA Vol. 2, No. 2 June, 1941 CONTENTS AUTHOR ARTICLES TAKATA, M. MURASUGI, T. TAKATk , S . : Grand-legende Untersuchungen über die Kosmobiologie Exist- enzfrage der "vierten" Sonnenstrahlung. P. 165 UEHARA, M. : Studies on the Precipitation Reaction, XI. A New Theory on the Fluctuation of the Antigen Titer in the Precipitation Reaction. P. 26l End of Vol. 2, No, 3> September, 1941 242 RESTRICTED M-AB ENCLOSURE ID), continued ACTA SEROLOGICA ET IMMUNOLOGICA Vol. 2, No. 4 December, 1941 CONTENTS AUTHOR ARTICLES FUKUDA, T. : Clinical Application of the Shwartzman Filtrate. P. 443 OGATA, T. ISIDA, E. ; Studies on Factors Determining the Arthus Phenomenon I. Cor- relativeness between Antibody, Antigen and Tissue Reactivity. P. 453 ISHIDA, E, : Studies on Factors Determining the Arthus Phenomenon. 11. Observation of the Arthus Phenomenon in the Multiple Reac- tion Systems, P, 487 AKAZA, H. : Concerning Anaphylaxis and Tolerance of the Guinea Pig to Quinine. P. 503 NEMOTO, H. : On the Sensitising Ability of Hormone Preparations of the Ovary. P. 511 IGUCHI, T. : Effects of Vitamins, Morphine and Calcium upon Reactions Caused by Acetylcholine. P. 517 OSHIMA, K. ; Relationship between Pollens, Leaves and Bulbs, as shown by Anaphylacitic Phenomena. P. 527 MIYATA, K. : On Denaturation of Mixed Milks by Heat. P. 539 SAICUHAYAMA, Y.; On alleviation of the Anaphylactic Reaction by Cholineester- ase and Hlstamlnase, Applied Simultaneously. P. 545 OOEI, J. ; Untersuchungen über den Kammel, aem das Forssmamsche Antigen fehlt. P. 551 UENO, S. CHUNG, S. H. : Konservierung der Antikorper durch Zusatz von Kochsalz. F. 585 FUKUDA, T. RIN, T. K. IWATSUKI, D. OGATA, T. : Therapeutic Influences of the Shwartzman Filtrate upon Several Inflammatory Diseases. P, 597 End of Vol. 2, No. 4, December, 1941 ACTA SEROLOGICA ET IMMUNOLOGICA Vol. 3, No. 1 April, 1942 CONTENTS AUTHOR ARTICLES ANDO, E. : Problems in the Study of Bacterial Vaccines. P. 1 243 M-AB RESTRICTED ENCLOSURE ID), continued BASUGI, K. : Studies on the Complement Action. I. On the Nature of the Brand Modification. P. 33 BASUGI, K. ; Studies on the Complement Action. 11, On the Mechanism of the Complement Fixation Reaction. P. 53 MATSURA, T, ; On the Specificity of the Lens as Seen from a New Point of View. I, Observation of the Lens as a Whole. P. 73 MATSURA, T. : On the Specificity of the Lens as Seen from a New Point of View. 11. Observation of the Kristalline Fractions of the Lens, ?. 97 MIYATA, K. GOTODA, K. : Production of Anaphylactic Antibodies for Two Antigens. P. 109 SAKURAYAMA, Y.; An Experiment of Sensitisation and Provocation by Oral Ap- plication of the Yolk and White of the Egg. AOKI, M. : Shwartzman Phenomenon Induced by Pollens of Quercus acutis- sima, Quercus serrate and Alnus japonica. P, 123 EISHI, N. : Über das Verhaltnls zwischen den Typen der Cholera-Vibrionen und den Residuen-Antigen. P, 133 SATO, M. : Über die Beziehungen zwischen der Entstehung der experimen- tellen Pneumonie durch den Frlendlander'schen Pneumobazillus und der Immunitat (I. Mitteilung). P. 141 AOSHIMA, 3. : Über die Formolgel-reaktion bei verschiedenen Hautkrankheiten usw., insbesondere bei Viruskrankheiten. P. 157 End of Vol. 3, No. 1, April, 1942 ACTA SEROLOGICA ET IMMUNOLOGIGA Vol. 3, No. 2 August, 1942 CONTENTS AUTHOR ARTICLES FUKE, F, ; Die immunoblologisohe Bedeutung der bakteriellen Polysaccha- ride. P. 18? SATO, M. ; Über die Beziehungen zwischen der Entstehung der experimen- tellen Pneumonie durch den Friedlander'schen Pneumobazillus und der Immunitat. (11, Mitteilung) P. 203 SHIBATA, N. : Serological Studies of the Cerebrospinal Fluid. I. Serolog- ical Constituents of the Normal Cerebrospinal Fluid. P, 217 SHIBATA, N. : Serological Studies of the Cerebrospinal Fluid, 11. Sero- logical Constituents of the Cerospinal Fluids in Various Diseases. P. 231 244 RESTRICTED M-AB ENCLOSURE ID), continued UENO, S. LI, K. T. : Beitrage zur Serodiagnose der Lues. P. 241 YAMAMORI, A. : Theoretical Considerations on the Precipitation Reaction (I). On Various Phenomena in the Mixture Tests. P, 255 YAMAMORI, A. : Theoretical Considerations on the Precipitation Reaction (II). On Various Phenomena in the Ring Tests. P. 273 End of Vol. 3, No. 2, August, 1942 ACTA SEROLOGICA ET IMMUNOLOGICA Vol. 3, No. 3 December, 1942 CONTENTS AUTHOR ARTICLES ANDO, K. : Serological Studies on Serum Fractions, On the Antigenicity of Antibody Globulins. P. 307 YAMAZAKI, Y. YAMAZAKI, H. : Experimental Anaphylaxis Induced by Formaldehyde. P. 341 MARUTA, T. : An Investigation of Anaphylactic Antibody in the Cerebrospin- al Fluid of the Rabbit. P. 351 OSHIMA, K. : Experimental Anaphylaxis Induced by Nickel Compounds. P. 359 RI, 0. KAYAMA, T. ; The Influence of the Acidosis and Alkalosis upon the Serum Anaphylaxis in Animal Experiments. P. 369 KUROYA, M. KAWAKAMI, H. : A New Diagnostic Method for Typhus Fever by Precipitation Reaction of Polysaccharide Antigen Isolated from B. Proteus Xl 9 from the Blood of Patients. P. 377 KITAMURA, I. Serologiscb-bistopatbologiscbe Untersucbungen über das thus-Phanoraen. I. Histopatbologlscbe Veranderungen beim ohus-Phanomen mit Berucksuchtigung auf der serologischen saktionen. P. 3&9 KIT AMUR A, I. : Serologisch-histopathologische Untersuciiungen über das Arthus-Phanomen. 11, Über die Spezifitat der histologischen Veranderung beim Arthus-Phanomen. Vergleich mit der geweb- licben Ausserungen des Shwarztman-Phanomens, P, 401 End of Vol. 3, No. 3, December, 1942 245 M-AB RESTRICTED ENCLOSURE (D)t continued ACTA SEROLOGICA ET IMMUNOLOGICA Vol. 4, No. 1 March, 1943 CONTENTS AUTHOR ARTICLES ANDO, K. : On the nature of Antibodies. P, 1 HAYASIDA, T. : Experimentelle Untersuchungen über die Wechelbeziehungen zwischen bakteriellen Infektionen und Gewebsumstlmmung. P. 33 HOJIMA, M. : Über den serologischen Nachweis des Kasestoffes bei der Tuberkulose. P. 51 AKIMOTO, S. : Serological Reinvestigations on Hemoglobin. P. 81 HIBINO, H. : On the Mechanism of Action of Virulicidin for Vaccine Virus. P. 99 HIBINO, N. A New Micromethod for Detecting Vaccine Virus in the Blood Stream of the Vaccine Inoculated Rabbit, End of Vol. 4, No, 1, March, 1943 ACTA SEROLOGICA ET IMMUNOLOGICA Vol. 4, No. 2 August, 1943 CONTENTS AUTHOR ARTICLES KAWAKITA, Y. : Serum Therapy in Virus Diseases, P. 157 HOJO, S. : Contribution to the Rieckenberg Phenomenon. I. Experiments with Bacteria. P. 197 HOJO, S. : Contribution to the Rieckenberg Phenomenon. 11, Experiments with Erythrocytes. P. 223 KIYOKAWA, T. ; Uher Brandsche Modifikation. P. 235 KIYOKAWA, T. : Uher Wasserkomplement. P. 259 KIYOKAWA, T. : Uher die Hamolysegeschwindigkeit, P. 277 KONDO, K. : Pharmacological Studies on the Toxin of Bacillus Dysenteriae Shiga. P. 281 End of Vol, 4, No, 2, August, 1943 246 RESTRICTED M-AB ENCLOSURE (D), continued ACTA SEROLOGICA ET IMMUNOLOGICA Vol. 4, No. 3 December, 1943 CONTENTS AUTHOR ARTICLES SATO, T. : Studies on the Lipoid Agglutination. I, Agglutination test with Syphilitic Serum. P. 369 SATO, T. : Studies on the Lipoid Agglutination. 11. Practical Applica- tion of the Agglutination Test for Syphilis. P. 395 INUZUKA, T. : Serological Studies of Fibrinogen. I. On Specificity of Fibrinogen, P. 405 INUZUKA, T. : Serological Studies of Fibrinogen. 11. On the Action of Antibody against Fibrinogen in the Blood Coagulation. P, 421 KIKUCHI, T. : Studies on the Relationship between Precipitation Reaction and Allergic Reaction. P. 433 YAMADA, N. : On Conditions Determining the Production of the Serum Figure by the Special Drying Method. P. 457 End of Vol. 4, No. 3, December, 1943 ACTA SEROLQGICA ET IMMUNOLOGICA Vol. 5, No. 1 April, 1944 CONTENTS AUTHOR ARTICLES MATSUMOTO, M. ; A Theoretical considerations of the precipitation reaction. Amelioration of the Yamamori’s theory. P, 43 ENDO, T. YEYAMA, M. : The enforcing ability of alum and gum arable in sensitizing guinea pigs. P. 53 NAKAGAWA, Y. : Studies on the Analysis of antibodies. Part 111. 0, H. and Vi antibodies of typhoid bacillus. P. 61 NAKAGAWA, Y. : Studies on the analysis of antibodies. Part IV. Studies on normal antibodies. P. 65 TAKEDA, Y. SEN, Y. : Experimental symmetrical cortical necrosis of kidneys pro- duced by the endotoxin of B. dysenteriae Shiga. P. 75 SUZUKI, K. : Specifity of serum protein fractions observed by the precip- itation reaction. P. 79 SEN, Y. : Tiber die Immunitat der Tuberkulose auf dem Grunde vom Gesich- tspunkt aus der Komplementbindungsreaktion (I. Mitteilung.). P. 97 End of Vol. 5, No. 1, April, 1944 247 M-AB RESTRICTED ENCLOSURE (D), continued THE JAPANESE JOURNAL OF DERMATOLOGY AND VENEREOLOGY Vol. 51, No. 1 January, 1942 CONTENTS AUTHOR ARTICLES ; Ein Fall von Haemangloperitheliom der Haut. P. 1 KITAMURA, S. ARIMOTO, T. lUCHI, I. : Klinische Untersuohungen auf dem Gebiete der Dermatologic über den wahren Blutzuckerspiegel, insbesondere über den hydrolysierbaren Blutzuckergehalt. P. 3 TAKEMURA, T. : Biologische und tierexperlmentelle Beitrage zu den Akti- nomyceten, bebst Bemerkungen zur Therapie der Aktinomykose. End of Vol. 51, No. 1, January, 1942 THE JAPANESE JOURNAL OF DERMATOLOGY AND VENEREOLOGY Vol. $l, No. 2 February, 1942 CONTENTS AUTHOR ARTICLES MITSUMOTO, S. : Histamingehalt der gesunden Menschenhaut. P, 89 KITA, A. : Über die Leberfunktion bei Syphilis und bei antiluetlscher Behandlung. I. Mitteilung; Über die Leberfunktion bei Syphiliskrahken. P. 92 ABE, F. : Studien über Antikorper der Haut. I. Mitteilung: Antikor- pergehalt der haut bei aktiver und passiver Inmunisierung. 11. Mittielung: Über die lokale Immunitat und die Antikor- perbildung der Haut bei perkutaner Inmunisierung (L). 111. Mitteilung: Über die lokale Immunitat und die Antikorper- bildung der Haut bei perkutaner Inmunisierung. (2) P. 10-1$ ARAKI, M. : Studien über die Dermatomykosen und ihre Erreger in Chosen. IV, Mitteilung: Über die Trichophytie in der Provinzen Kankyo-Nando und Kankyo-Fukuo (Nord-Korea). V, Mitteilung: Nochmals über die Trichophytie in Keijo und dessen Umgebung. Anhang: Zusammenfassung fur die Verbreitung der Trichophy- tonpilzin in Chosen. P, 162 End of Vol. 52, No. 2, February, 1942 248 RESTRICTED M-AB ENCLOSURE ID), continued THE JAPANESE JOURNAL OF DERMATOLOGY AND VENEREOLOGY Vol. 51, No. 3 March, 1942 CONTENTS AUTHOR ARTICLES MITSUMOTO, S. ; Reiz und Haut-Histamin. P. 185 KAWAMURA, T. : Über 15 Falle von Bourneville-Pringlescher Phalomatose. P. 188 ABE, F. : Studien über Antikorper der Haut. 17, Mitteilung: Exper- imentelle Untersuchung über die Einflusse auf Antikorper- gehalt der Haut, Einfluss der Blaokade des R.E.S. auf ant- ikorpergehalt rsp. Vermogen der Antikorperbildung der Haut. (L). IV. Mitteilung: Experimentelle Untersuchung über die Einflusse auf Antlkorpergehalt der Haut. Einflusse der Ar- zeneimitteln auf Antikorper rsp. Vermongen der Antikorper- bildung der Haut. (2). P. 245 URABE, K. : Studien über Pellagra in Chosen (Korea). XI. Mitteilung: Experimentelle Untersuchungen über die Entstehung des Ery- thems bel Pellagra. P. 257 End of Vol. 51, No. 3, March, 1942 THE JAPANESE JOURNAL OF DERMATOLOGY AND VENEREOLOGY Vol. 51, No. 4 April, 1942 CONTENTS AUTHOR ARTICLES NOMURA, H. TOYAMA, S. : Krankenstat stik der dermato-urologlschen Klinik an der Kaiserlichen Thoku-Universitat zu Sendai (1929-1936). P. 283 NAKAJO, A. : Über die Studie des Hautpigmentes (melanins) I. Mitteilung: Über die Einflusse Des Dioxybenzols auf Hautpigment. P. 295 MITSUMOTO, S. : Histamingehalt im Blut beim Insulin und elektrischen Shock. P. 309 NAKAMURA, I. : Einfluss des Dermatitlshautextrakts auf des Glykogen der Leber (I. Mitteilung). P. 314 OHARA, K. : Über die Tinea imbricate in Formosa. P, 339 End of Vol. $l, No. 4, April, 1942 249 M-AB RESTRICTED ENCLOSURE ID), continued THE JAPANESE JOURNAL OF DERMATOLOGY AND VENEREOLOGY Vol. 51, No. 5 May, 1942 CONTENTS AUTHOR ARTICLES HARADA, A. : Beltrage zur Sclerodermia diffusa. P. 379 SAITO, H. SEKIMURA, T. SAITO, K. ; Acrosclerosls. P. 424 End of Vol. 51, No. 5, May, 1942 THE JAPANESE JOURNAL OF DERMATOLOGY AND VENEREOLOGY Yol. 51, No. 6 “ June, 1942 CONTENTS AUTHOR ARTICLES MITSUMOTO, S. ; Der Einfluss der Formaldhyd-Traubenzudker-Losung gegen lokale Anaphylaxie. P. 519 OKUMA, T. : Über den Einfluss von verschiedenen Hormonen, vegetativen Nervengiften und Histamin entfiftenden Mitteln auf die Salva- rsananaphylaxie. P. 525 YOSHIHIRO, I. ; Beitrage zur Kenntnis von Elinik und Pathologie der Osmi- drosis axillae. I. Mitteilung: Statische Beobachtungen über Osmidrosis axillae. 11. Mitteilung: Über die Hist- ologischen Befunde der Achselaut. P. 557 End of Vol. 51, No, 6, June, 1942 JAPANESE JOURNAL OF ZOOLOGY Transactions and Abstracts Vol. IX, No. 2 March 30, 1941 CONI’ENTS AUTHOR ARTICLES IMAI, S. : Seven New Deep-Sea Fishes Obtained in Sagami Sea and Suruga Bay. P. 233 KINOSHITA, H. : Initiation of Entrapped Circuit Wave in a Scyphomedusa, Mastigias papua. P. 209 250 RESTRICTED M-AB ENCLOSURE (D), continued KINOSITA, H. : Conduction of Impulse in Superficial Nervous System of Sea- urchin. P. 221 MIKAMI, Y. ; Experimental Studies on the Development of the Eye in Urodele Triturus pyrrhogaster. P, 303 MUCAMI, Y. : Experimental Analysis of the Wolffian Lens-Regeneration in Adult Newt, Triturus pyrrhogaster. P. 269 MIYASHITA, Y. : Observations on an Entomiscid Parasite of Erioohoir japon- icus de Haan, Entiomella fluviatilis n. g., n. sp,. P. 251 NAKAMURA, N. : Effect of Light on the Regeneration in Synceryne nipponica. P. 165 NAKAMURA, N. : Secondary Formation of Gills in Branchiura sowerbyi by the Transformation of Trunk Segments. P. 195 SUGINO, H. : Homopolar Union in Planaria gonocephala. P. 175 End of Vol. IX, No. 2, March 30, 1941 JAPANESE JOURNAL OF ZOOLOGY Transactions and Abstracts Yol. X, No. 1 January 15, 1942 CONTENTS AUTHOR ARTICLES SUEHIRO, Y. ; A Study on the Digestive System and Feeding Habits of Fish. P. 1 End of Vol. X, No. 1, Januray 15, 1942 JAPANESE JOURNAL OF ZOOLOGY Transactions and Abstracts Vol. X, No. 2 July 20, 1942 CONTENTS AUTHOR ARTICLES FUJIWAGA, M. : Reproduction, Development and Hearing of Penaeus Japonicus Bate. P. 305 End of Vol. X, No. 2, July 20, 1942 251 M-AB RESTRICTED ENCLOSURE (DJ, continued JAPANESE JOURNAL OF ZOOLOGY Transactions and Abstracts Vol. X, No. 3 November 10, 1943 CONTENTS AUTHOR ARTICLES ANDO, B. ; Über die Leber, die Gallengange und den Pankreadgang von Delphinus mit vergleichend-anatomischen Bemerkungen. P, 395 ONODA, B. : Notes on the Development of Some Japanese Echinoids. Report IV. Hybridization Experiments with Some Japanese Echinoids. P. 407 YAMAGUCHI, S. : Studies on the Helminth Fauna of Japan. Part 43. Mammalian Nematodes, IV, P, 427 YAMAGUCHI, S. : Life History of a Frog Tapeworm Ophiotaenia ranae Yamaguchi, 1938. P. 455 YAMAGUCHI> S. : On the Morophology of the Larval Forms of Pasagonimus west- ermanii, with Special Reference to their SXcretory System, Page 461 KITADA, T. . : Disturbances Initiated from Naked Surface of Muscle Proto- plasm. P, 469 End of Vol. X, No, 3, November 10, 1943 THE JAPANESE JOURNAL OF EXPERIMENTAL MEDICINE Vol, 199 »Nos. 1-3 February-June, 1941 CONTENTS AUTHOR ARTICLES SUAGI, T. OBAYASHI, Y. NCGAMI, T. : The influence of sulfanilamide upon experimental tuberculo- sis. P. 1 ISHII, N. SHIMIZU, S. : The effect of sulfapyrldine on experimental spirochaetosis recurrentis. P. 5 TETSUMOTO, S. : Sterilizing action of aromatic acids. P. 11 TETSUMOTO, S. : Sterilizing action of phenols. P. 17 CHIGIRA, S. : Experimentelle Untersuchung über die anaphylaxie. I. Teil. Acetylcholinshock und dessen Beziehung zu dem anaphylaktisch- en shock. P. 23 CHIGIRA, S. : Experimental!e Untersuchung über die anaphylaxle. 11. Teil. Über die 1m Serum der Ratte und Maus im anaphylaktischen Schock nachweisbaren wirkstoffe. P. 27 NAKAMURA., K. ; Nouvelle opinion sur la production du choc anaphylactique, specialement sur le role de 11acethylcholine dans L’anaphy- laxie. P. 31 End of Vol. 19, Nos. 1-3, February-June, 1941 252 RESTRICTED M-AB ENCLOSURE (E) RESTRICTED M-AB ENCLOSURE (E) MATERIEL AND EQUIPMENT COLLECTED BY FIELD UNIT NO. 4 5250 TECHNICAL INTELLEGENCE COMPANY, MEDICAL SECTION LIST OF BOX NUMBERS Box "A” Page 254 Box "B" Page 254 Box "C" Page 255 Box "D" Page 256 Box "E" Page 256 Box "F" Page 256 Box "G" Page 257 Box "H" Page 258 Box "I” Page 258 Box "J" Page 259 Box "K" Page 259 Box "L" Page 259 Box "M" Page 260 Box "N" Page 260 Box "0? Page 261 Box "P" Page 264 Box "Q" Page 266 Box "R” Page 270 Box "S" Page 271 Box MT" Page 271 Box "U" Page 272 Box "V" Page 273 Box "W" Page 274 Box "X" Page 276 Box "Y" Page 277 Box "AA" Page 277 Items Packed Separate By Number Page 278 Addendum To Items Separately Packed Page 279 253 M-AB RESTRICTED ENCLOSURE (E) MATERIEL AND EQUIPMENT COLLECTED 3Y FIELD UNIT NO. 4 5250 TECHNICAL INTELLEGENCE COMPANY, MEDICAL SECTION FIELD UNIT NO. 4 5250 TECHNICAL INTELLIGENCE COMPANY Medical Section ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500. SHIPPING LIST, BOX "A". ITEM NUMBER TENTATIVE NOMENCLATURE 79 Kit, surgical instrument, Navy 80 Paper, X-ray, Navy 81 Blood Plasma, human M-9 82 Charts, wound, type "A", Navy 83 Charts, wound, type "A", Navy 84 Set, still heads for As. det. 85 Apparatus, lung-tying, Kilsinar's 86 Set, absorbing tubes, As. det. 87 Set, comparator, PH det. 88 Accessories, As. det. 89 Set, syphilis test M-10 90 Set, amputation knives 91 Hygrometer, hair 92 Set, pipette and syringe 93 Colorimeter and accessories 94 Set, bougies, metal 9$ Set, artery clips 96 Set, "heating lever” 97 Set, accessories, As. det. 93 Still, glass small ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500. SHIPPING LIST, BOX "B". ITEM NUMBER TENTATIVE NOMENCLATURE 99 Meter, blood pressure, large 100 Microcamera, new type 101 Set, cranial drills 102 Goggles, white, cotton 103 Kit, chlorine oet., OT 104 Psychometer, electric 105 Conductlvitymeter 106 Microsaccharimeter M-10 107 Case, instrument, plastic 108 Set, hypodermic, small 254 RESTRICTED M-AB ENCLOSURE IK), continued ITEM NUMBER TENTATIVE NOMENCLATURE 109 Set, scalpel 110 Set, arsenic test MlO 111 Accessories, microscope, Leitz 112 Stereoscopes, 2 each, (different) 113 Goggles, "Malikl"-type 114 Appliance, chest measuring. Navy 115 Cap, surgery. Navy 116 Flashlight, Navy 117 Instrument "automatic filling", Navy 118 Scissors, bullet. Navy 119 Extractor, bullet. Navy 120 Accessories, incubator 121 Catathermometer 122 Tonometer 123 Lever, jaw 124 Set, microprinting, "Suzuki*s” 125 Apparatus, vision-testing 126 Set, test lenses, spherical 127 Set, small 128 Opthalmoscope, new type 129 Meter, touch perception 130 Meter, pulse 131 Kit, dental accessories MO2 132 Set, disecting, large 133 Set, probe 134 Attachments, diathermy 135 Set, As, det., "Katsue Ishi" 136 Set, test leases, cylindrical ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "C" ITEM NUMBER TENTATIVE NOMENCLATURE 15 Lung capacity meter 137 Microcamera, small 13S Set, battery, with rheostat 139 Goggles, X-ray 140 Instrument, orthopedic, Sheiaar 141 Set, bottles, small 142 Set, instrument, post-mortem 143 Case, first aid, large, Navy 144 Set, eye surgery 145 Set, test lenses, cylindrical 146 Searchlight, 4-5 volt. Navy 147 Searchlight, 3,0 volt, Navy 146 Kit, water testing, field 149 Apron, X-ray operators 150 Mash, X-ray operators 151 Gloves, X-ray operators 152 Stage, microscope, electrically heated 255 M-AB RESTRICTED ENCLOSURE (E), continued ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "D". ITEM NUMBER TENTATIVE NOMENCLATURE 22 Indirect blood-transfusion set 34 Camera, X-ray, 33mm, Navy type, 2 each 153 Set, dental surgery, No, 2, Navy 154 Microtome, small 155 Set, surgical instrument, nasal 156 Set, electric drill 157 Apparatus, anaesthesia, 2 each 158 Restraining apparatus, 2 each ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500. SHIPPING LIST BOX "E". * ITEM NUMBER TENTATIVE NOMENCLATURE 33 Camera, 35mm,, X-ray, Army type, 2 each 159 Set, lead characters, X-ray marking 160 Set, syringe 161 Viewer, X-ray 162 Set, pH det., colorimeter MlO 163 Meg-ohmmeter 164 Cup, suction 165 Sleeves, rubber 166 Bandage, eye, celluloid 167 Set, electric cautery 168 Set, burette 169 Set, Instrument, orthopedic, "Osage" 170 Set, pulmonary 171 Set, urine analysis MlO 172 Liners, boot, white cotton ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST BOX "F". ITEM NUMBER TENTATIVE NOMENCLATURE 30 Microscope, fold., med., Leitz 31 Microscope, fold., med., new type 173 Set, flexible bougie 174 Plate counters 175 Set, arsenic test MlO 176 Microtomes, 2 each 177 Colorimeter 173 Apron, rubber 256 RESTRICTED M-AB ENCLOSURE (E), continued ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO $OO SKIPPING LIST, BOX "G". ITEM NUMBER TENTATIVE NOMENCLATURE 26 Polygraph, with case 179 Sun lamp, type 1 180 Haenoglobinometer MXO 181 Vulcanizer, dental, complete MO2 182 Stand, laboratory, dental MO2 183 Vulcanizing mould, large, dental MO2 184 Vulcanizing mould, small, dental MO2 18$ Asbestos block, dental MO2 186 Anvil, dental MO2 187 Mallet, dental MO2 188 Blowpipe, dental MO2 189 Kit, dental, field, Navy MO2 190 Ladle, dental MO2 191 Jaw holders, impression, full jaw, assorted, 2 each MO2 191 Jaw holders, impression, partial, 2 each MO2 192 Denture holder, large MO2 193 Denture holder, small MO2 194 Gas generator, small, dental MO2 19$ Burner, Bunsen, lab, 197 Set, retractors 198 Splints, arm and hand, wooden, 2 each 199 Braces, 3 each 200 Screws, medical, assorted 201 Bone plates, orthopedic, assorted 202 Catathermometer, Army type 203 Stage micrometer 204 Splints, foot, metal, 2 each 20$ Brace, neck 206 Tube, fused quartz 207 Braces, orthopedic, metal, assorted 209 Accessories, blood counting app. 210 Set, eye dropper syringe 211 Tourniquets, with special clamp 212 Thermometers, incubator 213 Plate, glass 214 Plates, Red Cross 21$ Reservoir, whole blood 216 Bougie, flexible, plastic 217 Drill, hand 218 Shoulder brace, leather 219 Covers, med. microscope, 3 each 220 Traction hooks, 2 each 221 Cages, insect, 2 each 222 Bags, urine, paper 223 Cover, medical 0 instrument, substitute 257 M-AB RESTRICTED ENCLOSURE (E). continued ITEM 3 TO Bjs SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "H". ITEM NUMBER TEATATIVE NOMENCLATURE 224 Surgeon’s clothing, white, 2 sets 225 Kit, Gas casualty, new type QP 226 Kit, Gas casualty, new type QC 227 Kit, first aid, pilots, type A 228 Kit, first aid, pilots, type B 229 Kit, first aid, small, new type 230 Kit, first aid, for tank crew 231 Test chart, color blindness 232 Otogoniometer 233 Polygraph, Dr. Kure-Sakai*3 234 X-ray exposuremeter ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SKIPPING LIST, BOX "I". ITEM NUMBER TENTATIVE NOMENCLATURE 238 Film viewer, 35jam. individual X-ray photographs 239 Double boiler, tin-lined, for preparation of medicine 241 Accessories, incomplete, for diathermy set, large 244 Set, body measurement 249 Tank, developing, 35mm. ind. X-ray plates 256 Tourniquet, pneumatic 251 File, glass cutting, 2 each 252 Set, abdominal retractor 253 Holder, platinum wire, 2 each 254 Insignia, patients, officers and enlisted men 255 Knives, splint-making, 2 each 256 Kit, tool, splint making, 2 each 259 Kit, first aid, first modification 260 Kit, first aid, aircraft, second modification 263 lamp, darkroom. X-ray 265 Set, film marking. X-ray 266 Cup, medium, feeding 267 Set, aspirator, with attachments 268 Books, color perception charts 269 Books, color perception charts in English 258 RESTRICTED M-AB ENCLOSURE IE), continued ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "J". ITEM NUMBER TENTATIVE NOMENCLATURE 245 Set, amputation instruments, small 246 Set, mechanical eyechart 247 Tensometer, back muscles 257 Set, surgical instrument in canvas carrying case 258 Kit, field, Medical Officers, substitute type, 2 each 264 Set, nasal washing 270 Penicillin mold Ml 2 ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "K". ITEM NUMBER TENTATIVE NOMENCLATURE 271 Apparatus, examination, 3 types, vet. 272 Apparatus, castrating, vet. 273 Apparatus, clysterizing, vet. 274 Set, pregnancy examination, vet. 275 Set, water testing, vet, Ml 2 276 Apparatus, clysterizing, siphon-type, vet. 277 Hone 278 Apparatus, urine-absorption, vet. 279 Canvas, irrigator, vet. 280 Set, syringe, successive, vet. 281 Kit, medical, vet. 282 Psychometer, 2 each, vet. 283 Apparatus, liquid medicine, vet. 284 Kit, surgical, vet. 235 Kit, surgical, vet. ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 50C SHIPPING LIST, BOX "L". ITEM NUMBER TENTATIVE NOMENCLATURE 286 Colorimeter, vet. 287 Microtome, vet, 288 Kit, decontaminating, vet. QC 289 Mirror, headband, vet. 290 Set, water testing, vet. 291 Syringe set, vet, 292 Calipers, vet. 293 Apparatus, surgical, Russian type, vet. 259 M-A B RESTRICTED ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 294 Balance, vet. 295 Sphygmomanometer, American type, vet. 296 Sterilizer, Russian type, vet. ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO $OO SHIPPING LIST, BOX "M". ITEM NUMBER TENTATIVE NOMENCLATURE 297 Set, castrating, vet, 298 Set, surgical instrument, vet. 299 Set, surgical instrument, vet. 300 Apparatus, castrating, vet. 301 Scissors, vet. 302 Lamps, kerosine, 4 types, vet. 303 Lamps, gasoline, 3 types, vet. 304 Bellows, vet. 305 Syringe, "Julafer", vet. 306 Instrument, mouth inspecting, vet. 307 Lamp, operating, vet. 308 Syringe, vet. 309 Colorimeter, vet. 310 Tail cutter, vet. 311 Irrigator, vet, 2 each 312 Searchlamp 313 Splint, horse leg, vet. 314 Set, syringe, vet. 315 Instrument, surgical, vet. 316 Set, syringe, vet. 317 Curettes, vet. 318 Syringe, saline, vet. ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO $OO SHIPPING LIST BOX "N". ITEM NUMBER TENTATIVE NOMENCLATURE 319 Kit, veterinary medicine, 7 types 320 Kits, gas casualty, veterinary, 5 types QP 321 Kit, dental, vet. MO2 322 Kit, veterinary medicine, German, 2 types 323 Kit, syringe, veterinary, 3 types 324 Kit, First Aid, tank, medical 325 Kit, gas scout 326 Pack, medical, back, privates 260 RESTRICTED M-AB ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 327 Kit, medical, bach, NCO'S 328 Pouch, medical, enlisted man's 329 Pouch, medical officers 330 Pack, medical, tropical countries, privates MOl 331 Pack, medical, tropical countries, NCO’S ITEM TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "0" ITEM NUMBER TENTATIVE NOMENCLATURE 332 Vulcanizer, dental 333 Kit, "iron and needle", vet. 334 "Binder", vet. 335 Container, cloth, water resisting, vet. 336 Support, horse knee, vet. 337 Filter, type undetermined, glass and metal, vet. 338 Set, knives, dissecting, vet. 339 Lamp, electrid, vet. 340 Syringe, small, vet. 341 Thermometer, vet, 342 Shears, vet. with leather case. 343 Furnace, petroleum 344 Instruments, dental, 7 types, vet. 345 Condenser, glass, vet. 346 Sampler, fecal matter, horse 347 Syringe pump, vet, 2 types 348 Instrument, type undetermined, vet. 349 Holder, needle, vet. 350 Curette, vet, 3sl Retractor, vet. assorted, 7 types. 352 Sound 353 Scissors 354 Needle, spinal 355 Tail cutter 356 Bone saw 357 Flag, hospital, vet. 353 Ureters, two types, vet. 359 Banners, vet. commissary, 2 each 360 Saws, Gigle, vet. 361 Curettes, plastic, vet. 4 types 362 Syringe, small, vet. 363 Medicine feed bag, horse, vet. 364 Samples of brushes, combs, etc. vet. 36$ Syringe, glass with pipettes 366 Kit, gas casualty treatment, vet, 367 Muzzle, dog, vet. 368 Filtration apparatus, vet. 369 Set, orthopedic instru., vet. 370 Gutter, tail, vet. 261 M-AB RESTRICTED Eh CLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 371 Hood, horse, vet. 372 Stethoscope, vet. 373 Kit, vet medicine, cloth bag. 374 Container, leather Tor surgical instruments, vet. 375 Kit, vet. small 376 Speculum, vaginal, vet. 5 types 377 Catheters, rubber, vet. 373 Forceps, vet. 379 Cutters, vet. 380 Rongeurs, vet. 2 each 381 Scissors, vet. 2 each 310 Lucene sol. MO2 511 Lactylphenetidin pdr. Ml 2 512 Lodlnon amps. Ml 2 513 Luetenol amps. Ml 2 514 Lienalin Ml 2 515 Livealin amps. Ml 2 516 Labon sol. Ml 2 517 Migozai tab. Ml 2 518 Miniglin amps. Ml 2 519 Mogrol amps. Ml 2 520 Moljudol amps, Ml 2 521 Myotanin amps. Ml 2 522 Mizuhonin pdr. Ml 2 523 Mibunol pdr. Ml 2 524 Mizuhonin sol. Ml 2 525 Madarmon pdr. Ml 2 526 Neobosan amps. Ml 2 527 Neo Psychorin Ml 2 528 Neo Resin Ml 2 529 Neo Cain Ml 2 530 Neo Dispetal Ml 2 531 Neo Albasil Ml 2 532 Neo Ehramisol amps, Ml 2 533 Neo Geburti amps. Ml 2 534 Neo Urihin Ml 2 535 Nutrogen Ml 2 536 Natagon Ml 2 537 Normalactol sol. Ml 2 538 Normaton pdr. Ml 2 539 Neo Chramisol Ml 2 540 Otolysin Ml 2 541 Opostatin tab, Ml 2 542 Opogenin amps. Ml 2 543 Opogenin pdr. Ml 2 544 Opostatin crys. Ml 2 545 Ovaharmon tab, Ml 2 546 Oophormin amps. Ml 2 547 Oporenin Ml 2 548 Ovastron amp, Ml 2 549 Oryzanin amps. Ml 2 550 Osvarsan Ml 2 551 Oranln amp, Ml 2 552 Ozaenol Ml 2 553 Ovisan tab, Ml 2 * 554 Perosulf amps. Ml 2 262 RESTRICTED M-AB ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 555 Pyogenol amps. Ml 2 556 Puberogen amp. Ml 2 557 Para Thlosalcol amps. Ml 2 558 Panos pdr. Ml 2 559 Prokliman tab. Ml 2 560 Phosphoric Acid tab. Ml 2 561 Philopon tab. Ml 2 562 Prostigmln "Roche" amps. Ml 2 563 Peristatin amps. Ml 2 564 Peer San amps. Ml 2 565 Prae Harmon Ml 2 566 Ponsil sol. amps. 567 Ponsil pdr. 568 Pyriseptin 569 Proseptin tab, 570 Pelanin amps. 571 Pelanin Benzoat amps. 572 Phytin crys. $73 $74 s7s $76 $77 $7B $79 580 $Bl 582 583 584 $B5 586 $B7 588 589 590 591 592 $93 $94 s9s 596 Sulfaguanidum tablets 597 Samidol amps, 598 Solustlbosan amps. 599 Solustibosan sol. 600 Syphilis Serodiagnostlgum 601 Seragazome Black Hair Dye 602 Strychnine Nitrate pdr. 603 Salicylo Salicylic acid pdr. 604 Slaso Brocanon amps. 605 Sulzol pdr, 606 Sajaurln amps. 607 Suguiron amps. 608 Silinal amps. 609 Salomethyl ointment 610 Skoka Ikenyo tab. 611 Sedalon tab. 263 M-AB RESTRICTED ENCLOSURE (E), continued ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "P”. ITEM NUMBER TENTATIVE NOMENCLATURE 419 Aethynal Ml 2 420 Alctor amps. Ml 2 421 Aluesin amps. Ml 2 422 Antistreptococcic Serum for Scarlet Never MlO 423 Anti Serum against Weil’s disease MlO 424 Antireysipelatic Vaccine MlO 425 Acetoanilid pdr. Ml 2 426 Antasthol amps. Ml 2 427 Atonin Y. T. amps. Ml 2 428 Athinon amps. Ml 2 429 Adiplon amps. Ml 2 430 Antimoiiin amps. Ml 2 431 Agomensln amps. Ml 2 432 Anti-Typhoid vaccine tabs. MlO 433 Allestin amps. Ml 2 434 Antimonal amps. Ml 2 43$ Argent Colloidal /Vagin Ml 2 436 Agomensin tablets Ml 2 437 Antitussin MlO 433 Baccain Sol. amps. 439 Blutose, pdr. 440 Bi-Distilled Water, amps. 441 Bluklan amps. 442 Bitomason tablets. 443 Bromiveton amps. 444 Borroginol Ointment. 445 Blood Plasma, normal, human MO9 446 Crysotan Ml 2 447 Ciba Ephinephrinechloride, amps. Ml 2 443 Cumarin pdr. Ml 2 449 Cruculon liq. Ml 2 450 Cornidin amps. Ml 2 451 Cardinon amps. Ml 2 452 Cepharanthin amps. Ml 2 453 Cepharanthin tablets Ml 2 454 Garcon Ml 2 455 Calysanin pdr. Ml 2 456 Ciba Epinephrine sol. Ml 2 457 Choleretin amps, Ml 2 458 Gonvalon amps, Ml 2 459 Campanol sol. Ml 2 460 Cocatin pdr. Ml 2 461 Cholegol pdr. Ml 2 462 Chininum Aethyl Carbonicum pdr. Ml 2 463 Gibalbumin amps. 464 Dazol sol. Ml 2 465 Digifoline sol. Ml 2 466 Epirenamine amps. Ml 2 467 Epirenamine sol. Ml 2 468 Ephedrine Nagai, 5 grams Ml 2 469 Epheptol amps. Ml 2 470 Equijodin pdr. Ml 2 471 Equbromin pdr. Ml 2 264 RESTRICTED M-AB ENCLOSURE (E), continued ITEM number tentative nomenclature 472 Evipan Natrium Ml 2 a 73 Fondent ointment Ml 2 474 Ferrophytin Pills Ml 2 475 Ferrophytin crystals Ml 2 476 Gynadol amps. Ml 2 477 Gono Ostran tablets Ml 2 478 Glubrom pdr. Ml 2 479 Gono-Serovacclne Ml 2 480 Guajacolum Ml 2 481 Guajacolum camphorate pdr. Ml 2 482 Gono Broccanon amps. Ml 2 483 Gerbamin Ml 2 484 Guajacol Exihose Ml 2 485 Gitosan amps. Ml 2 486 Homoflavin amps. Ml 2 487 Hodin amps. Ml 2 488 Kydein pdr. Ml 2 489 Hydnocarin amps. Ml 2 490 Hellmin amp. Ml 2 491 Hiscoval amps. Ml 2 492 Helsgen sol. Ml 2 493 Haematype Ml 2 494 Heminal Ml 2 495 Hydrocodeln Phosphoricurn Ml 2 496 Ichthol Vagin Ml 2 497 Interenln amps. Ml 2 498 Isatole tablets Ml 2 499 Iflon amp. Ml 2. 500 Iveton amps. Ml 2 501 Jodkali Vagin Ml 2 502 Juvamon amps. Ml 2 503 Jecora Ml 2 $O4 Jod Brocanon amps. 505 Jod Polytamin Ml 2 506 Kavidol pdr. Ml 2 507 Kalium Sulfaguajacol cry. Ml 2 s>oB Kaeflose sol. Ml 2 509 Katol Ml 2 612 Soxyl pdr. 613 Secartin amps. 614 Sexanol 615 Staplon tab, 616 Splenogen amps. 617 Tubconln amps. M 2 613 Tuberculin MlO 619 Tanvonin Ml 2 620 Taltarin pdr. Ml 2 621 Taltarin tab. Ml 2 622 Takastin Atropin amps. Ml 2 623 Taka Diastase tablets Ml 2 624 Tetropotoxine amps. Ml 2 625 Thymitussin sol. Ml 2 620 Tussiast amps. Ml 2 627 Tropococain hydrochloride amps. Ml 2 628 Thyradin amps. Ml 2 629 Thyradin sol, Ml 2 265 M-AB RESTRICTED ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 630 Thymophogen amps. Ml 2 631 Thymophogen pdr. Ml 2 632 Toricalo Ml 2 633 Tonirop Ml 2 634 Tonikum "Roche” sol, Ml 2 635 Tusoln pdr. Ml 2 636 Tenesmin amps. Ml 2 637 Utro Proseptin amps. Ml 2 638 Utro Brocanon amps. Ml 2 639 Umarmon amps. Ml 2 640 Urinon pdr. Ml 2 641 Urargol amps. Ml 2 642 Viton amps. Ml 2 643 Vioform antiseptic Ml 2 644 Yatren Casein amps. Ml 2 ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "Q". ITEM NUMBER TENTATIVE NOMENCLATURE 645 Blood Serum, Human MlO 646 Phosphoric Acid tablets Ml 2 647 Godein pdr. Ml 2 , 64S Philopon tablets Ml 2 649 Neo-Calgonogen amps. Ml 2 650 Detoxol "Banyu" Ml 2 651 Berinose solution Ml 2 652 Carotin amps. Ml 2 653 Percamin-ol amps. Ml 2 654 Tomipron Ml 2 655 Kromozin sol, Ml 2 656 Sapltone sol. Ml 2 657 Mayer’s reagent Ml 2 658 Bismutin Ml 2 659 Lienalin Ml 2 660 Salo Urtin Ml 2 661 Folia Digitalis Concisa Ml 2 662 Bluklagen Ml 2 663 Bismisol Ml 2 664 Gylotropin Ml 2 665 Gasoedem-Serum, ’’Behring” MlO 666 Cocaine Hydrochloride amps. Ml 2 667 Kehsin pdr. Ml 2 668 Neothesin pdr. Ml 2 669 Pituglasin amps. Ml 2 670 Kypoform Ml 2 671 Tubunlc "Roche” Ml 2 672 Tacarose Ml 2 673 Pronptin amps. Ml 2 674 Salmon Ml 2 266 RESTRICTED M-AB ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 675 Monponin Ml 2 6?6 Natro-astivarsan Ml 2 677 Javamon Ml 2 678 Saveolnatrium Ml 2 679 Arsaminal Ml 2 68C Spirocid Ml 2 631 Galkose Ml 2 582 Hlsogasuiin Ml 2 683 Peniocol Ml 2 684 Sulfehramisol Ml 2 685 Neo Arzenol Ml 2 686 Magna-G Ml 2 687 Lobelinum Hydrochloride Ml 2 688 Lacarnol Ml 2 689 Cornldin Ml 2 690 Sajodin Ml 2 691 Myo-Arsemin Ml 2 692 Neosavial Ml 2 693 Numal '’Roche” Ml 2 694 Hospitan Ml 2 695 Isopral Ml 2 696 B. Z. tablets Ml 2 697 Analgesia Ml 2 698 Thromberry Ml 2 699 Pyridinin-Qiglucoseschwefligesaures Natrium Ml 2 700 Scoloid Ml 2 701 Tanapan Ml 2 7G2 Scopon Ml 2 703 Ergotin "Futaba" Ml 2 704 Tamaokisery akusho Ml 2 705 Fastase Ml 2 706 Tepuchi-Matsu Ml 2 707 Neo-Thrombin Ml 2 708 Ovobral Ml 2 709 Clauden Pellets Ml 2 710 Icterosan Ml 2 711 Rateol Ml 2 712 Teberan amps. Ml 2 713 Totumit Ml 2 714 Beninese amps. Ml 2 715 Triblsmin Ml 2 716 Jusonin Ml 2 717 Brotanin Ml 2 718 Pltuglasin Ml 2 719 Mono Acigul Ml 2 720 Mecikre Ml 2 721 Trubaratin Ml 2 722 Gataflavin Ml 2 723 Papayotase Ml 2 724 Homunaharmon Ml 2 725 Provitamin A Ml 2 726 Kuhtamin Ml 2 727 Spirobismol Ml 2 728 Gynergen Ml 2 729 Myo Salvarsan Ml 2 730 Renuharmon Ml 2 267 M-AB RESTRICTED ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 731 Aktcor Ml 2 732 Digilanogen sol. Ml 2 734 Digilanogen amps. Ml 2 735 Pyolysin Ml 2 736 Acykal Ml 2 737 Sandorman Ml 2 738 Kiosin Ml 2 739 Neocain Ml 2 740 Danmeck Ml 2 741 Endojodln Ml 2 742 Kallikron Ml 2 743 Indoramln Ml 2 744 Brotacin Ml 2 745 Ganyakusui Ml 2 746 Aneme Ml 2 747 Lechtenin Ml 2 748 Coca colae tab. Ml 2 749 lodipin Ml 2 750 Orthofom Ml 2 751 Langela Ml 2 752 Edera Ml 2 753 Shltsu Ml 2 754 Blustin Ml 2 755 Omnadln Ml 2 756 Adnaldin Ml 2 757 Coagulln "Ciba" Ml 2 758 TJirombrin Ml 2 759 Arabrogen Ml 2 760 Globin sol. Ml 2 761 Ipecacuanhas amps, Ml 2 762 Uabanin Ml 2 763 Pandiglfol Ml 2 764 Amolisin amps. Ml 2 765 Diathylenoxyd Ml 2 766 Azur II Ml 2 767 Galaktose Ml 2 768 Glykokll Ml 2 769 Triketohydrindenhydrat Ml 2 770 Dimethylgloxin Ml 2 771 Benzildioxim Ml 2 772 Rosolsaure Ml 2 773 Xylose Ml 2 774 Rhamnose Ml 2 775 Thymolphthalein Ml 2 776 Diphenylamin Ml 2 777 Indolessigaaure Ml 2 778 Dichlnrphenolendopholnatrium Ml 2 779 Inosite Ml 2 780 Dulcit Ml 2 781 Trypaflavin Ml 2 782 Kinine tab. Ml 2 783 Lebanarin Ml 2 784 Antimalarla Mittel Ml 2 785 Roimetil Ml 2 786 Haisung Ml 2 787 Anti D. M. Ml 2 268 RESTRICTED M-AB ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 788 Hunterin Ml 2 789 Pituglandol Ml 2 790 Comet Omlnin Ml 2 791 Lebanarin 792 Neo Minoalin 793 Quinophenum 794 Otox B 795 Marukofen 796 Yome Oil 797 Hexamin-Salicyl-Coffein 798 Premaline 799 Perabrodll 800 Omunal 801 Novonol 802 Theoxan 803 Kidonln 804 Methylen Creosote 805 Sumikomo 806 Blenolin 807 Hexopban 808 Eutolmin 809 Fibrogen 810 Malaria tabs. Ml 2 811 Tokakina tabs. 812 Karojin ointment 813 Toriharomin 814 Glob, Olei Santali 81$ Eratin 816 Arushiren tabs, 817 Borraginol Ointment 818 Anaptol 819 Kachifer Tablets 820 Sovolin 821 Aterlan pdr. 822 Taugen 823 Iszilin 824 Apellagrin 82$ Igrosin 826 Kativ 827 Antivenom Serum, 4 vials MlO 828 Camphora Depurata "Pulv" 829 Neoarsaminel 830 A. M. C. 831 Neosporicide 832 Annaka sol. 833 Gluceserria 834 Sal Carolinum Factitium 83$ Unguentum Hhoicum 836 Mercury Ointment 837 Sporcide 338 Creolin 839 Base Plate Paraffin 840 Frlstle Discs, #9 and #ll 841 Blanor MO2 842 Wax Sheets, #1 MO2 843 Crown and bridge cement MO2 269 M-AB RESTRICTED ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 844 False teeth 845 Polishing disks MO2 847 Carborundum wheels MO2 348 S.P.M. Flux MO2 849 Platinum Flask MO2 846 Triolite MO2 850 Solder MO2 851 Paper disks MO2 852 Dental paint MO2 853 Oden MO2 854 Dental sterilizer, solution MO2 855 Dental floss MO2 856 Temporary stopping, 2 each MO2 857 Platinum solder MO2 858 Jeweler’s rough MO2 859 Wax, sticky MO2 860 Rustless alloy MO2 861 Borax Paste MO2 862 Dura Silver MO2 863 Carborundum disks MO2 864 Carborundum speed wheels MO2 865 Cement MO2 866 Silver alloy 867 Formocresa MO2 868 Blue Inlay Wax MO2 869 Dental Burrs MO2 870 Brass Ligature MO2 871 Rubber, distilled MO2 8?2 X-ray film, dental MO2 873 Orden MO2 874 Carbolite disks MO2 875 Bite blocks MO2 876 "Theoe" MO2 877 Gold wire MO2 878 Dental "Neogie" MO2 ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "R " • ITEM NUMBER TENTATIVE NOMENCLATURE 382 Apparatus, Thermocautery, German, vet. 383 Gutter, type undetermined, W/case, vet. 384 Set, surgical instrument, vet. 385 Set, syringe, 20 cc, vet., w/wooden case 380 B©t, syringe, 30 cc, vet., w/wooden case -337 Set, syringe, 50 cc, vet., w/wooden case Set, syringe, 5 cC, vet., w/metal case 388 Board, cutting, rifled 389 Flask, graduated, w/case 390 Set, "tumor-treatment”, vet. * 270 RESTRICTED M-AB ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 391 Set, trephaning instrument, vet. 392 Set, microscopic accessories, vet. 393 Set, histological preparation, vet 66 Instrument, horse measurement, 3 types 394 Syringe, glass, 10 cc, w/filling stopper, 2 each 395 Applicator, powder, bakelite, vet. 2 types 396 Inhaler, oxygen, dog, vet. 397 Set, vulva operator, vet, 398 Set, syringe, w/rubberoid case 399 Kit, clysterizlng, Chinese, vet. 400 Instruments, vet. Samples from China, 2 doz. assorted 401 Apparatus, glass, type undetermined vet, 402 Accessories, microscope, Leitz 403 Kit, vet. med, w/leather case 404 Records, vet. blank forms 405 Lamp, electric, vet. 406 Container, portable, type undetermined, vet. 407 Bucket, rubber ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "S". ITEM NUMBER TENTATIVE NOMENCLATURE 879 Apparatus, X-ray, field, vet, 880 Accessories, "Shiron" incubator, vet. 881 Instrument type undetermined 882 Apron, lead, X-ray, vet. 883 Vulcanizer, vet. 884 Case, canvas, for lamp electric, vet, 885 Lamp, kerosene 886 Bucket, canvas and metal, vet. ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "T". ITEM number tentative nomenclature 887 Set, testing, urine and water 888 Viewer, X-ray plates, vet. 889 Slings, for carrying cutter, medical, 2 each 890 Pouches, medical, leg, paratrooper, 2 pair 891 Set, First aid, vet. 892 Gloves, rubber, gas casualty treatment, vet. 893 Bandage, horse, vet., assorted, 6 each 271 M-AB RESTRICTED ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 894 Funnel, leather, vet. 895 Hood, horse, vet. 896 Suit, veterinary’s, all rubber 897 Pouch, rubberized, vet, 2 each 898 Pads, flexible, wool, vet., 5 types 899 Harness, restraining, vet., 4 types 900 Markers, route, hospital, vet. ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "U”. ITEM NUMBER TENTATIVE NOMENCLATURE 901 Normal horse serum 902 Exama Medicine 903 "Enema'1 904 "Colloid liquor" 905 Camels, hair 906 Pepper Oil 907 Camphor tar 90S Gold varnish, dental 909 Leather cream 910 Horse serum 911 Ryrisuron 912 Greosol pdr. 913 Tar of Flea Dung 914 Tincture of lodine w/contalner 915 Peruvian Balsem 916 Kreollnum 917 Neo Poleon 913 Sucwalen 919 Pomegranate skin 920 "Nutrious food for Sick Horses" 921 "Stirrup sore" medicine 922 Carbanoylcholinchloride 923 Neollser solid 924 "Effective ointment" 925 Wilson oint, 926 Vaseline substitute 927 "Supo" acid 928 Arrowroot roo 929 Centinol ointment 930 Concentrated tar 931 "Gland serum" 932 Oxfull tabs. 933 Injection for "soft bone disease" 934 Rape seed oil 935 Dried serum pdr. 936 - Camphor solution 937 New Sterilizer liquid 938 Coconut oil 939 Dlsulfanllamlde 272 RESTRICTED M-AB ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 940 Cresol solid 941 Charbon test sol. 942 Morphine Chloride ITEMS TO BE SHIPPED TO TECHINGAL INTELLIGENCE DEPOT, APO 500 SHIPPING LISTT BOX "V". ITEM NUMBER TENTATIVE NOMENCLATURE 943 Ovisot amps, 944 Osuban tablets 945 Gonometon amps. 946 Thorogestin amps. 947 Frostbite cream 948 Dlazo Reaction solution, 2 bottles 949 Wax ointment 950 Cholera vaccine MlO 951 Antityphus vaccine MlO 952 Dried agar media MlO 953 Dried Ox Gall MlO 954 Epidemic Meningitis vaccine MlO 955 Prophylactic against Paratyphoid "A" MlO 956 Paratyphoid type A and B MlO 957 Antigasgangraen serum MlO 958 Prophylactic against Paratyphoid "B" MlO 959 Prophylactic against Typhoid MlO 960 Tetanus vaccine MlO 961 Plague vaccine MlO 962 Gasgangraen vaccine MlO 963 Antitetanus vaccine MlO 964 Diphtheria prophylactic MlO 965 Antivenom serum MlO §66 Diagnostic serum for typhoid MlO 967 Test paper for poisoned water, (cyanic acid) 968 Test paper for poisoned water, (sublimate and heavy metals) 969 Diagnostic serum for early Typhus MlO 970 Endo media tablets MlO 971 Artificial Lacianuamolke MlO 972 Kaufman media tab. MlO 973 Dysenterie bacillus med. tab. MlO 974 Diagnostic serum for Paratyphoid B MlO 975 Antitetanus serum MlO 976 Diagnostic serum for cholera MlO 977 Diagnostic serum for B paradysenterie Y MlO 978 Reagent for Wassermann reaction MlO 979 Diagnostic serum for B Gaetnerie MlO 980 Diagnostic serum for BPfs 981 Diagnostic serum for B Dysenterie MlO 982 Tuberculosis media tablets MlO 983 Neutral red media tablets MlO 984 Diagnostic serum for paratyphoid bacillus MlO M-AB RESTRICTED ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 985 Anti Serum against Weil's disease MlO 986 Paratyphoid bacillus type ”C" MlO 987 Bacillus Proteus X-19 diagnostic for Widal's reaction MlO 988 Diphtheria toxin sol. for Shick test 989 Paratyphoid Bacillus type "A" MlO 990 Paratyphoid Bacillus type "B" MlO 991 Typhoid Bacillus MlO 992 Tuberculin MlO 993 Antigasgangraen serum MlO 994 Anti Typhus vaccine MlO 995 Anti Tetanic serum MlO 996 Anti Tuberculosis prophylactic (8.C.G.) MlO 997 Standard blood typing serum MlO 998 Aronson media tablet MlO 999 Dried Lingershelm media with lactose MlO 1000 Dried Lingershelm media MlO 1001 Ducrey vaccine MlO 1002 Wassermann reaction MlO 1003 Dried neutral peptone 1004 Rassel media tablets MlO 1005 Dried vaccine (anti-pock) MlO 1007 Diagnostic serum for Paratyphoid bacillus "C" MlO ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "W". ITEM NUMBER TENTATIVE NOMENCLATURE 1008 Taurin N.G. 1009 Anthenln pdr. 1010 Aleviatln pdr. 1011 Cement, dental, 9 shades MO2 1012 "Schleich II" sol, amps. 1013 Emplaste, saponat, German 1014 Ekien Magotin 1015 Borotopin 1016 Mercury "Resorbin" 1017 Dikezal amps. 1018 Pneumosil sol. 1019 Theociso amps, 1020 Mutterpflaster, German 1021 Neo Furomon 1022 Neo Cystol 1023 Neo Staagen 1024 "Mex" 1025 Aiwajin 1026 Adberin 1027 Electoid Sulphur 1028 Decocti Uva Ursi 1029 Atominose 1030 Hydnocaln 274 RESTRICTED M-AB ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 1031 Hydnol 1032 Jodonascin 1033 Guleon 1034 "Neo Sarat" 1035 "Kion" crystals 1036 Halorain 1037 Sangostop (Dutch) 1033 Marukopan 1039 Regerot Salbe 1040 Novasurol 1041 Bismuth sublodlde 1042 Taeniol 1043 Sanarin 1044 Sanarin 1045 Kavlkan 1046 Bren Paste 1047 Slangengif serum 1048 Leucoteer 1049 Zellatmin 10$0 Alkanza 1051 Peryth 1052 Gono Goccen vaccine MlO 1053 Pyrabitalum 10$4 Barbitalura 1055 Percamin 1056 Aethyluim Aminobenzoicum 1057 Karbunken 1058 Neohexal 1059 Eustoimin 1060 Hoppus 1061 Flavinin 1062 Nelkegan 1063 Imamicol 1064 Anocuron 1065 Nagravon 1066 Lynosol 1067 Sexcol 1068 Lypase 1069 Matxin 1070 Urlzinol 1071 Phthlsol 1072 Eatan 1073 Neo Pieron 1074 Borovertin 1075 p-Oxydiphenylacetase 1076 Erlsot-"Comet" 1077 Ericatin 1073 Fischlin 1079 Papain 1080 Depromin 1081 Phloxin 1082 Utalmol 1083 Neothesin 1084 Leprol 1085 Agotin 1086 Neu Maruconinum 275 M-AB RESTRICTED ENCLOSURE (E), continued 1087 Hectalin 1088 Humanin 1089 Ghinaselin 1090 Ymolin 1091 Smilgen 1092 Tuberculin MlO 1093 Strong sterilizer, liquid 1094 Livenol amps. 1095 Tabellim 1096 Pile cure 1097 "Tonsilitls" pdr. 1098 Qma pdr. 1099 Purgative tablets 1100 Halomin amps, 1101 Oxygen sublimate 1102 Army drug for Influenza, 2 bottles 1103 Frostbite solution 1104 "Poison gas destroyer" QC 1105 Adaper tablets 1106 Liver tab. 1107 Tectral tablets 1108 "Gelp" sol. 1109 Heherin yeast pdr. 1110 Guen extract 1111 Datuloid tab. 1112 Neo cycitol 1113 Dandellla, dried 1114 Hifuoru, (sore cure) 1115 Parpltone 1116 Burn ointment QE LIST OF ITMES TO BE SHIPPED TO TECHNICAL INTELLIGENCE CENTER, APO 500 SHIPPING LIST, BOX "X". ITEM NUMBER TENTATIVE NOMENCLATURE 1126 Kit, dental, small, substitute 1127 Tachometer 1128 Urethral speculum 1129 Amphotropine 1130 "Tussiast" powder 1131 "Vaccine tablet, antl-typhique" 1132 "Gasoeden serum" solution 1133 Lamp, electric, portable 1134 Tensometer, hand, small 1135 "Soxyl" 1136 "Flzilin" solution 1137 Thermometers new type 1133 Sharpener, cork borers 1139 Stapler, surgical 1140 Kit, nasal surgery 1141 Dressing, wet, "No. 900" 1142 Set, dental surgery, large 1143 Set, cork-borers 276 RESTRICTED M-AB ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 1144 Part for fluoroscope (item 18) 1145 Lamp, examination, with headband H46 Surgeon's clothing, assorted 1147 Kit, orthopedic clamps 1148 Forceps, gauze, wooden 1149 Clamp, Ice bag, new type 1150 Kit, enema 1131 Paper, oilsilk, for dressings 1132 Kit, "liquid absorbing", accessories 1133 Lamp, nasal examination 1154 Clock, interval-recording 1135 Rabies vaccine LIST OF ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE CENTER, APO 500 SHIPPING LIST, BOX "Y". ITEM NUMBER TENTATIVE NOMENCLATURE 1156 Kit, alcoholometer 1157 Kit, cautery, large 1158 Kit, urethral speculum 11$9 Kit, joint flexibility measurement 1160 Kit, proctoscope 1161 Kit, bone fixation 1162 Kit, animal dissection 1163 Pouch, medical soldier, canvas and fur 1J.64 Kit, first aid, aircraft, original type MO6 1165 Microscope, folding, small, leather case 1166 Balance, folding case, small 1167 Balance, Harvard beam, medium ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST, BOX "AA". ITEM NUMBER TENTATIVE NOMENCLATURE 1227 Scales, 500 gram capacity- -1228 Kit, insect collection 1229 Kit, canules 1230 Pins, orthopedic, (Steiman), 2 types 1231 Microscope, folding, small. (This item and item #1163 differ from previously reported microscope in construction of case only). 1232 Hone, four-sided, large 277 M- A B RESTRICTED EH CLOSURE (E), continued ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE DEPOT, APO 500 SHIPPING LIST; ITEMS ARE PAG ICED SEPARATE BY NUMBER. ITEM NUMBER TENTATIVE NOMENCLATURE CASES 1 Set, water testing, portable, small 2 2 Laboratory, field, portable, (Army) 61 3 X-ray, field, portable, w/generator 15 4 Laboratory, gas and water testing portable 9 5 Hospital, gas casualty, horse-carried Q.G 4 6 Chest, water filter 1 7 Chest, gas casualty 1 8 Chest, Hypodermic 1 9 Chest, microscope accessories 1 10 Chest, field sterilizer 1 11 Chair, dental, folding 1 12 Generator, ozone 1 13 Electrometer 1 14 Container, water, air-drop 1 15 Meter, lung capacity 1 17 Parachute, cargo, medical, cotton 1 18 Fluoroscope, camera style 35nim 2 19 Litter, bamboo, folding 1 20 Dynamometer, bach mlscles 1 23 Dispensing kit, wooden 1 24 Reservoir for stomach pump 1 32 Microscope, type undetermined 1 40 Laboratory, field, portable, (Division) 47 41 Hospital, field, portable 18 42 Chest, sterilizer, hospital, field 1 43 Set, meat inspection 9 44 Set, meat inspection 11 4$ Hospital, field, vet, 5 46 Hospital, field, vet. 7 47 Set, gas casualty treatment, field, vet. 2 43 Set, disease prevention, vet. 17 49 Hospital, shipboard, portable, vet. 5 50 Set, examination, (purchasing), vet. 3 51 Set, surgical instrument, vet. 2 52 Set, surgical instrument, vet. 2 53 Set, meat Inspection 2 54 Set, surgical instrument, shipboard, vet. 3 55 Set, dispensing, vet. 3 56 Set, surgical, vet. 9 57 Set, dog treatment 1 53 Chest, gas casualty, vet. 1 59 Chest, horse examination 1 60 Set, surgical hospital, vet, 7 61 Chest, laboratory, portable, vet, 1 62 Chest, dog examination, (Purchasing), vet. 1 63 Chest, surgical instrument, vet. (German) 1 64 Kit, surgical, vet. 1 65 Unit, X-ray, field, vet. 2 68 Chest, laboratory, portable, small, vet. 1 69 Chest, laboratory, portable, vet. 1 70 Sterilizer, field, vet, 1 71 Power unit, X-ray, field, portable, vet. 1 72 Meter, -CO2 in air 1 278 RESTRICTED M-AB ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 73 Tubes, X-ray, new type 9 74 Tubes, diathermy, new type 2 242 Cnest, surgical instrument, type 99, box #1 (Box #2 recovered June 1945) 1 243 Chest, surgical instrument, newest type 1 243 Chest, surg. instrument, basic, type undet. 1 261 Balance, torsion, 500mg, 1 262 Sphygmopiezograph 1 408 Chest, first aid, aircraft, sub. type 1 409 Cover, litter, metal 1 410 Meter, gas in blood 1 411 Heater, individual patient, gasoline 1 412 Tent, individual patient 1 413 Container, air-drop, med. sup. w/parachute 2 each 2 4-14 Set, treatment, military pigeon, vet, 1 415 Set, treatment, military dog, vet. 1 416 Kit, developing, X-ray 1 417 Can, gasoline 1 418 Kit, X-ray, accessories I 1 1117 Infra Red Ray apparatus 3 1118 Hospital, field, portable, (Regimental) 16 1119 Hospital, shipboard 19 1120 Gas casualty treatment station 2 1121 Crate, medical supply, sub. type 1 1122 Anti gas casuslty Kit, sub. type, officers 2 1123 Kit, anti gas casualty, sub. type, NGO 1 1124 Kit, anti gas casualty, sub. type, privates 1 LIST OP ITEMS TO BE SHIPPED TO TECHNICAL INTELLIGENCE CENTER, APO 500. ADDENDUM TO SHIPPING LIST OP ITEMS SEPARATELY PACKED. ITEM NUMBER TENTATIVE NOMENCLATURE 1125 Set, gas casualty treatment, 2 cases 1168 Pouch, medical soldier’s, fur 1169 Kit, "blood circulation treatment" 1170 Set, abdominal retractors, large 1171 Generator, oxygen 1172 Barometer, mercury 1173 Accessories, oxygen apparatus 1174 Kit, surgical instrument, type undetermined 279 M-AB ENCLOSURE (E), continued ITEM NUMBER TENTATIVE NOMENCLATURE 1233 Gastrograph 1234 Vison tester, new type 1235 Scales, 100 kg capacity 1236 Goniometer 1237 Kit, X-ray accessories, small 1238 Microscope Camera, in case 1239 Accessories, microscope camera in case 1240 Set, laboratory, small, 2 case 1241 Meter, depth perception, in case 1242 Perimeter, for visual test 1243 Pulmotor, oxygen, 2 types 1244 Film, X-ray, large, in case 1245 Camera, X-ray, "for motor car" 1246 "Reducing Camera" in case 1247 Set, bacteriological laboratory, incomplete, 22 cases 280 NTJ