ANESTHETICS IN7 LABOR. \I ■f BY S. S. TODD, M. D. Professor of Obstetrics and Diseases of Women in the Kansas City College of Physicians and Surgeons; Late President and Honorary Member of the Medical Association of the State of Missouri, etc. REPRINTED FROM THE TRANSACTIONS OF THE MEDICAL ASSOCI- ATION OF THE STATE OF MISSOURI FOR 1875. ON THE USE OF ANESTHETICS IN LABOR. BY S. S. TODD, M. D. [.Reprinted from the Transactions of the Medical Asso- ciation of the State of Missouri for 1875.] In the prosecution of the duty imposed on me by your commit- tee I have sought to avail myself of nearly everything that has been written upon the subject during the past twenty-eight years. My suc- cess in this, however, has hardly equalled my expectations, for the field is so very broad, and covers such a lengthened period of pa- tient trial and acrimonious debate, and further, is so void of sta- tistics that I find myself in possession of a vast array of con- flicting opinions and but few facts. That these opinions have much value and will not fail to make their impress on those who have given the subject but little attention, cannot be denied, how- ever completely they may fail to satisfy the demands of scientific accuracy. In order to make our information as complete as may be I have not restricted this paper to my own observations, or the ob- servations of my immediate acquaintances, nor to the literature of the subject as we find it in our libraries; but have endeavored to avail myself also of the experience of a large number of silent, though generally competent observers distributed over a wide field of observation, as well as the most recent and matured views of those who have betimes contributed to the literature of the sub- ject. To effect this the following list of queries was prepared : i. Estimate the per - ntage of all cases of Normal Labor in which you administer Anesthetics. 2. Estimate the frequency 2 with which you employ anesthetics in turning, forceps delivery, and other painful obstetric operations. 3. At what period in nor mal labors do you begin with the use of anesthetics ? 4. To what extent is the induction of anesthesia carried in normal labors? 5. What anesthetic is used and by what kind of appliance? 6. What bad results to the woman have you known to follow anesthesia ? 7. What bad results to the child? 8. Have you ever known flood- ing, retention of the placenta, or rupture of the perineum to re- sult from the use of anesthetics? 9. Can you cite any case of death to the woman directly traceable to the use of anesthetics during labor? 10. From your own experience would you counsel a more extended use of anesthetics in Normal Labor ? Over six hundred circular letters embodying these questions were prepared, four hundred of which were addressed to obstetri cal writers and teachers, prominent obstetricians, leading surgeons and practitioners of medicine, both in this country and in Europe, embracing, among others less known, the greater part of those whose names have been in any way associated with the subject and whose present views were not otherwise known. About two hun- dred were addressed to country and village practitioners, resident of our own State and of Kansas. The result in replies, though not so great in point of numbers as might have been expected, ha been exceedingly gratifying in many respects. Two hundred and sixty-two replies have been received, though in some cases the writers have failed to answer all the questions asked. Many have not only answered the questions asked but have written long let- ters detailing their experience, giving history of cases, quotations from authors, citations of books, papers, etc. I may be permitted here to say, as a just tribute to the parties themselves and to the judgment of the masses of our profession whose award of distinc- tion is seldom misplaced, that the most courteous and elaborate replies, in the main, have come from those who are esteemed the best, the bravest, and the busiest men in the profession ! ANESTHESIA IN PAINFUL, PROTRACTED AND DIFFICULT DELIVERIES. The first announcements of painless surgery with ether, and subsequently by the use of chloroform, created the utmost amaze- ment all over .the civilized world. I well remember, being a student at the time, how the medical world was astonished with the startling news, and with what incredulity some received it. Nothing probably was more natural, and surely nothing was more certain, than that some made up their minds instantaneously— prejudice (prejudgment) you may call it,—saying to themselves, if not to others, “this will never do ; assuredly God will not permit man to do these things and live !” Is this not true ? It was even worse yet when that grand old man, Sir James Simpson—he whose sovereign made him a baronet, and whom God made a prince—it was, I say, even worse yet when Simpson proposed to introduce this diablerie into midwifery ! Not into surgical obstetrics only 3 did he propose to carry it, but into the home of every lying-in woman, despite ancestral curses and contemporaneous execrations! That I may not appear to exaggerate the consternation thus awak- ened, I recall one instance in the language of Dr. Robert Lee. “Very soon after the discovery of its physiological effects,” said Dr. Lee, speaking of chloroform,” I was confounded by the an- nouncement of its application to midwifery.” [Med. Times and Gazette, Sep. 1854.] Before studying this matter closely I was of opinion that the profession were so nearly of one mind with respect to the use of anesthetics in almost every form of departure from easy labor, that I had proposed dealing very briefly with this branch of the subject. I have learned, however, that there is much less un- animity than I had thought. In Painful and Protracted Labors.—With few excep- tions, still, it may be said, the most strenuous opposers of anesthe- sia in normal labor concede that in labor attended with excessive pain and mental disquietude, or which promises to be of long duration, moderate anesthesia is not only allowable but of positive benefit. Particularly is there great unanimity in this, if it shall seem that the excessive suffering and delay are caused by spasmod- ic or reflex rigidity of the os uteri, or perineum. Anesthetics can- not be too highly commended also in those cases rendered tedi- ous by reason of inefficiency of the pains; the inefficiency being due to the want of co-ordination and concert of action on the part of the expulsive forces. This want of reciprocal action (misdirec- ted nerve force), happens ordinarily in, labors at term, but which are precipitated a few days, or a few hours, by a general hyper- sensibility of the patient, or some local irritation more or less well defined. With reference to arrest of labor under these circum- stances, Dr. Robert Barnes, of London, uses the following lan- guage: “It is not a figure .of speech to say that here chloroform acts like a charm. It may even save the necessity of resorting to instruments.”—[Obstet. Operations, p. 70.] Closely allied to this class are those cases of permature labor made tedious from want of development of uterine muscular fibre and the absence of other physiological and anatomical changes that pave the way to easy labor at term. Though in both of these classes chloroform would render excellent service, yet here it is, and particularly in the character of cases last mentioned, that sub cutaneous use of morphia and the chloral hydrate are especially beneficial. In these cases it is not expected that labor will ter- minate speedily; rest, and it may be sleep, is required, and the persistent effects both of morphia and the chloral hydrate render them exceedingly valuable agents, and preferable in many instan- ces to all other anesthetics. Opposition to anesthesia in these cases springs from a variety of causes, some of which we shall con- sider hereafter, inasmuch as the objections to anesthesia in cases of extreme suffering, or unusual delay, apply with equal, even greater force to common labor. 4 In Difficult Delivery.—The question of anesthetic obstet- ricy acquires unusual importance, in some respects, where the la- bor involves manual or instrumental aid ; such cases, necessitating more profound narcosis, approach more nearly the conditions present in ordinary surgery and demand the same precautions against danger. Now what does the profession throughout the civ- ilized world to-day hold with respect to anesthesia in this class of labors ? That sudden death from the anesthetic might take place sometimes in these cases of deeper anesthesia, as in ordinary surg- ery, is just what we might expect, but, curiously enough—a prob- lem we shall again have occasion to advert to, there is not yet such a case of death on record, unless we except the one reported by Dr. Routh in a discussion before the London Obstetrical Society, May, 1863, and quoted by Sansom. [Chloroform: Its Action and Administration, p. 2 2 7]'in which death took place during de- livery by the forceps, chloroform being administered by the nurse. Two other cases are cited by Sansom in which death took place a short time after forceps delivery, one reported by Dr. Pomeroy, of New York, and the other by Dr. Faye in “Schmidt’s Jarbuecher.” But, as Sansom says, “such accidents have occurred aforetime in- dependently of chloroform,” and “the positive evidence of the preservation of life by anesthesia greatly outweighs these doubtful signs of its danger.” Concerning anesthesia in Embryotomy, and the Caesarean Operation there is no difference of opinion. One would as soon think of discarding it in amputations of the leg, as to think of discarding it here. Objection, however, is sometimes made to its use in cases of Adherent Placenta, and by those who concede its value in obstetric surgery; an objection based upon a supposed liability to hemorrhage from paralysis of uterine muscular fibre in- duced by the anesthetic. That no such paralysis occurs unless under the most profound, and needless narcosis, will presently be shown. Its use in Turning is objected to by others, because, as they say, the act is easily and quickly accomplished, often with- out introducing the hand, and in a large proportion of cases causes little pain ; that insensibility to pain and relaxation of the cervix sufficient to allow the easy introduction of the hand, cannot be had, without narcosis to the extent of endangering life, directly, or subsequently through post partum hemorrhage, and that there- fore no adequate compensation is yielded for the risk incurred. Prof. Fordyce Barker, of New York, [Trans. New York Acad, of Med. 1861,] is undoubtedly correct when he says, “Its value in these cases is beyond controversy.” Agam, objections are urged against anesthesia in Forceps cases. It is said that the operation is not necessarily painful; that if the instrument be carefully introduced, properly applied, and dexter- ously used, the entire operation may be completed with little pain and but trifling constitutional disturbance. I can but admit that this is true of many cases, especially in the hands of those who constantly use the forceps where there is even inconsiderable de- 5 lay of the head at the outlet, but I am sure it is far from being true of all, even of a majority. Whoever has labored for an hour to seize the head at the superior strait, or a disproportionate head in the pelvic cavity, or drag a like head and the shoulders of an overgrown fetus through the inferior strait of an irritable, not to say irascible primiparous woman, without an anesthetic, must have seen the need of some such agent, else he has studied his own comfort and the patient’s welfare to little profit. The terror, too, inspired by the sight or thought of instruments probably con- tributes not a little to the untoward result that sometimes follows instrumental deliveries. It must not be forgotten also that a large number of forceps deliveries are hastened deliveries, as in asphyx- ia, eclampsia, concealed, and unavoidable hemorrhages, and that such rapid birth greatly endangers the perineum ; but if a suffi- cient degree of narcotism be induced this risk is much lessened, by reason of relaxation of the soft parts, save in those exceptional cases where distension is hindered by the presence in the vagina or at the vulvar outlet of cicatrices or a superabundance of adipose tissue. The objection that anesthesia removes a valuable index to the extent of any injury likely to be inflicted by the in- strument was well met, at the moment of its birth, by Prof. Simp- son when he asked Prof. Meigs, “would it be right and moral in a surgeon to deny to his patients the advantages of anesthesia, in order that their sensations and sufferings should make up for his want of anatomical and operative knowledge?” ; and further when he says in that same memorable “answer,” speaking of the introduction of the forceps, “it enables you without any pain to the patient, to Introduce your fingers for this purpose far more deeply between the head and maternal structures than you could do if the patient were awake, and in her usual sensitive state.”—[Works of Sir James Y. Simpson, Bart. Vol. 2, p. 1x8.] In considering the validity of objections to anesthesia in re- moval of adherent placenta, turning and extraction with the for- ceps, which objections reach me by letter from many excellent and unimpeachable sources, and which I find elsewhere, I cannot help half suspecting that in some instances, at least, the opposition should be imputed to an unsuspected and pre-conceived aversion to anesthesia in toto, save perhaps in the rarer cases of obstetric surgery, rather than to the results of experience. The remark will apply with equal propriety to some objections to anesthesia in nor- mal labor. No one, we presume, is rash enough to counsel the indiscrim- inate use of anesthetics in the cases we have been considering. The warmest advocates of anesthesia recognize and teach, to the contrary, the necessity of an adjudication in every individual case. While each must decide in a particular case for himself, what cases are in a general way suitable for its use, and what advantages are claimed for its employment in any case, the authority therefor, may now engage our notice. “Pain,” says Prof. Simpson, [loc. cit. p. 112.] “whenever it 6 is great in degree or great in duration, is in itself deleterious; and by shielding our patients by anesthetic measures against the more severe portions of the pains of parturition, we not only preserve them from the agony of their more immediate sufferings, but we preserve their constitutions also from the effects and consequences of these sufferings.” Again, [p. 25.] “When the state of anesthe- sia is adequately deep, it renders the patient quiet and unresisting during the required operative procedures; it prevents, on her part, those sudden shrinkings and changes of position which the boldest and firmest woman cannot sometimes abstain from when her mind and body have been worn out, as happens in most operative cases, by a previous long and protracted endurance of exhausting but still ineffectual labor pains;—the introduction of the hand into the maternal passages, or of the hand to guide our instruments, is greatly facilitated both by the passiveness and apathetic state of the mother, and by that relaxation of the passages which deep an- esthesia almost always induces ; and, lastly, this state of relaxation and dilatability renders the process of the artificial extraction of the infant through these passages alike more easy for the practi- tioner, less dangerous for the child, and more safe for the struc- tures of the mother.” With regard to the value of anesthesia in forceps delivery, Prof. Fordyce Barker, of New York, says: “If all due precau- tions are taken in introducing and locking the blades, the danger of injury to the mother and child is greatly decreased, because the perfect quietude and tranquillity of the patient is secured, and the operation can be performed with the greatest deliberation and carefulness, which is often impossible when the patient is under great excitement. Especially is this the case with regard to the safety of the perineum.” The same eminent authority, also, in a very brief and comprehensive way sums up its advantages thus, in turning : “There is much less resistance to the introduction of the hand ; as it is introduced without pain to the patient, it rarely requires to be withdrawn and re-introduced on account of the paralyzing effect of the uterine contraction ; the external and in- ternal manipulations are much more safely and expeditiously ac- complished, and there is less danger of injury to the internal sur- face of the uterus."—[Trans. N. Y. A.cad. of Med. 1861.] “In instrumental labor there can be no doubt that chloroform has tended to the presevation of life. Labors have thus been com- pleted, the patient being in a state of insensibility, when other wise delivery would have been impossible, and death would have occurred. * * * * The value of chloroform in operative midwifery is that it renders the patient passive in the hands of the practitioner, favors relaxation of the rigid tissues, lessens the suf- fering of the patient, and promotes convalescence by reducing the effects of shock and exhaustion.”—[Sansom, loc. cit. p. p. 226, 236.] Prof. Byford, of Chicago, uses the following language : “In tedious, difficult, and operative cases of labor, I feel as much 7 under obligation to use the anesthetic, and make as profound an impression with it, as in the performance of any of the more pain- ful surgical operations, and for all the same reasons.”—[Theory and Prac. of Obstetrics, 1873, P* 227-] “In all difficult, and especially in painful operations,” says Dr. Karl Schroeder, of Erlangen,” it is of immeasurable benefit to the patient; it also materially facilitates operations, and there- fore deserves to be always used in such cases.”—[Manual of Mid- wifery, 1873, P- 96-] Prof. Leishman, of Glasgow, thus indorses anesthesia: “The question of anesthetics seems to stand thus. In eclampsia, in some cases of mania, and in all cases of operative midwifery, it is without exaggeration, invaluable.”—[System of Midwifery, 1873, p. 693.] From the letters of one hundred and thirty-three correspon- dents, resident of the United States, the kingdom of Great Britain and Ireland, and continental Europe, who give precise data from their own practice, I find that : 86, or 64 per cent, use anesthesia in all operative cases of midwifery except when forbidden by some peculiarity of the case. 12, or 9 per cent, use it in all operative procedures except forceps cases. 5, or 3-7 Per cent, use it in all operative cases except in turn- ing. 7, or 5 per cent, use it in all operative cases except in turning and forceps cases. 11, or 8 percent, use it in 50 per cent, or less, of all opera- tive cases. 121, or 90.9 per cent, use it in a greater or lesser number of operative \:ases. 12, or 9.01 per cent do not use it in any of these cases. Among the 47 correspondents who discard anesthetics in operative midwifery, in whole (12) or in part (35), are the sub- joined names. To the question : “Will you give the frequency with which you employ Anesthetics in Turning, Forceps Delivery, and other painful Obstetric Operations,” the following replies were made : Dr. W. H. Bryant, Savannah, Mo.—“I use chloroform in delay- ed labor from rigidity of the os uteri and perineum, and in version; during the last seven years I have used the forceps once in every eight cases of labor, and without anesthetics in a single case.” Dr. J. P. Chesney, St. Joseph, Mo.—“Have never used them but once in version, and am entirely opposed to their use in instrumental interference.” Dr. D. W. Stormont, Topeka, Kan.—“Always to complete anesthesia, in forceps delivery and other painful opera- tions. For the last six years I have turned by postural, or ‘breast and knee’ position ; and so easy and comparatively painless is the operation, in this position, that I am surprised that it has not re- ceived more consideration at the hands of the profession generally. The use ofanesthetics would interfere with the position.” Dr. F. 8 M. Johnson, Platte City, Mo.—“I always employ anesthetics in turning, but sparingly in forceps delivery.” Prof. H. T. Cleaver, Keokuk, Iowa.—“In all cases where the hand has to be inserted (they are very rare)—but seldom in forceps cases.” Dr. David Prince, Jacksonville, 111.—“Always in turning, never in forceps cases.” Dr. J. S. Cleveland, Cincinnati, Ohio.—“Probably io per cent. I prefer operating without anesthesis.” Dr. C. D. Palmer, Cincinnati.—“Usually in turning ; very seldom in forceps delivery, unless demanding previous craniotomy.” Prof. S. Loving, Columbus, Ohio.—“Never in using the forceps, which should not give pain. In turning, if the woman is very timid, or if the contractions of the womb are so strong as to interfere ser- iously with the operation, I consider it proper to use chloroform or ether, and maintain anesthesia till the foot is secured, not after- ward.” Prof. D. N. Kinsman, Columbus, Ohio.—“I never use anesthetics in forceps deliveries, and have nevtr done so but once in turning.” Dr. J. M. Toner, Washington, D. C.— “In about 20 per cent, of turning. Do not use them in ordinary forceps de- liveries.” Of the 86 practitioners who resort to anesthesia in all opera- tive cases where it is not specially forbidden, 12 are members of this association, though it is proper to say that reports have not been received from all of its members. From among these 86 the following are selected and their reports are given in their own language. Says Dr. Bryant Grafton, Wyandotte, Kas.: “In all painful operations.” Dr. J. A. Coons, Spring Hill, Kas.: “I administer them in all cases of turning, forceps, and painful operations of whatever nature.” Dr. G. W. Haldeman, Paola, Kas.; “I never fail to use them under any of the aforementioned circum- stances.” Dr. W. W. Cochrane, Atchison, Kas : “I use them in all of these cases.” Dr. A. W. Reese, Warrensburg, Mo.: “I always use them.” Prof. J. Adams Allen, Chicago: “Almost without exception.” Prof. A. Sager, Ann Arbor, Mich.: “Always, except when hemorrhage from relaxation exists, or when the patient objects.” Prof. A. B. Palmer, Ann Arbor, Mich.— “I always use them in such cases.” Prof. R. N. Todd, Indian- apolis—“I use them in all such cases.” Prof. D. W. Yandell, Louisviile, Ky.—“In every case, unless the woman objects.” Res. Physician of Louisville Hospital—“Always.” Dr. John S. Sea- ton, Louisville, Ky.—“In all cases if used at all. In 1640 cases of labor I have never used instruments of any kind, but have turned often.” Dr. B. W. Avent, Memphis, Tenn.—“In all.” Dr. Jerome Cochrane, Mobile, Ala—“Always in turning and painful operations, and usually in forceps cases.” Prof. W. H. Daughty, Univ. Ga.—“Almost invariably.” Prof. M. Schuppert, New Orleans, who claims to be the discoverer of what is known as Nelaton's method of resuscitation in chloroform narcotism—“In every one of the named conditions.” Prof. T. G. Simons, Charleston, S. C.—“Always, unless special contra-indications 9 exist.” Prof. T. L. Latimer, Baltimore—“In all cases.” Prof. T. R. Brown, Baltimore—“In all cases where considerable pain is to be inflicted.” Prof. John Morris, Baltimore—“I always em- ploy anesthetics in turning, and think it good practice to use them in all instrumental cases.” Dr. W. Symington Brown, Stoneham, Mass.—“Invariably in all such cases.” Dr. W. L. Atlee, Phila- delphia (retired from the practice of midwifery)—“I employed anesthetics nearly always in turning, forceps delivery and painful obstetric operations.” Dr. W. R. Gillette, New York, “I always use them in obstetric operations.” Prof. Montrose A. Pallen, N. Y.—“Always when there are no cardiac or pulmonary contra-in- dications.” Prof E. S Bunker, Brooklyn, N. Y—“In turning always, and for all painful operations ; in forceps deliveries 90 per cent.” Prof. Fordyce Barker, New York—“In all cases of the kind, except where there has been previously dangerous hemor- rhage, as in placenta previa. ” Dr. Lombe Atthill, Dublin—“In turning always; in forceps delivery, about 50 per cent.—this refers solely to private practice. In other painful operations I use it (chloroform) nearly invariably.” Dr. J. Matthews Duncan, Edin- burg, Scotland—“In all.” Mr. Lawson Tait, Birmingham, Eng- land—“Invariably.” Dr. Arthur Steele, Liverpool, England— “In nearly all such cases I use anesthetics. In the tedious labors of irritable primiparge they are invaluable. In all operations it wonderfully aids the accoucheur, but here, of course, anesthesia must be pushed to the surgical degree, and an assistant to watch the administration should be insisted on.” Dr. J. Braxton Hicks, London—“In all cases of turning and other obstetric operations, though in some forceps cases I avoid their use unless full anesthe- sia is intended.” Prof. B. S. Schultze, Univ. of Jena—“I always use chloroform, if not especially contra-indicated, in turning, forceps delivery, and other painful operations.” Prof. Carl Braun- Fernwald, Univ. of Vienna—“In the above named operations, an- esthetics have always been used (in the great Vienna Hospital) with the best results for the last twenty-five years, and in one hun dred thousand cases.” For the last six years, I have myself resorted to anesthesia by chloroform in all protracted, painful and instrumental labors, unless some special reason existed for not doing so. The excep- tional cases are now rare. I quite agree with Dr. Brown, of Stoneham, Mass., “that no patient has ever persistently objected under such circumstances.” The number of exceptional cases would be still further reduced could I fully agree with the late Dr. Anstie, who says : “It is my firm persuasion that, with proper care, chloroform may be safely administered to any patient who is fit to undergo an operation at all, whether there be any existing dis- ease of heart, lungs or brain or not. I have never allowed the ex- istence of such disease to prevent my administering it, and I have never found any evil result.”—[Stimulants and Narcotics, p. 330.] During the ten years just passed, I have given chloroform in 34 cases requiring manual or instrumental aid ; part of them oc- 10 curing in my own practice, and part of them seen by me in con- sultation. Twenty-one of these were forceps cases, of which two died, one from eclampsia, and one from inter-current dysentery. Eleven were cases requiring version, of which number one died from eclampsia; one was a case of adherent placenta, and the other was a case of placenta previa, both of whom recovered. The ag- gregate of recoveries is 31, with 3 deaths. There was laceration of the perineum to the sphincter ani in one of the forceps cases, but in no case did hemorrhage follow, or was there retention of the placenta, except the case of adherent placenta already re- ferred to, and in no instance did the forceps seem to have been required as a result of the anesthetic. The results to the children were three still born, two of them being delivered by the forceps and one by turning. In no case was the fatal result, either to mother or child, imputed to the chloroform. The degree of narcosis ordinarily induced in these cases, is, so far as I have been able to learn, determined by the character of the case and the effects witnessed. Adopting Dr. Sansom’s divis- ion of narcosis into three stages—that of sopor, stupor and stertory between which, of course, there is no definite line of demarca- tion—we may say that in cases of painful or protracted labor, not requiring operative interference, anesthesia to the first degree, in which pain is abolished without loss of consciousness, is deemed to be sufficient. In all operative measures it is enough if the second degree, that of stupor, be induced and maintained, in which stage there is entire loss of consciousness, and a state of perfect quietude. It is certainly not the accepted belief that nar- cosis to the extent of causing complete relaxation of the uterus is ever necessary in version, as Dr. Barnes [Obstetric Operations, p. 184,] seems to think. Indeed, when we remember that the func- tions of the sympathetic system, of which the uterine force is one, are ordinarily the very latest to be extinguished in fatal cases of chloroform-narcotism, it is difficult to see how the “perfect flac- cidity,” which he deems essential, can be reached short of the very verge of dissolution. This flaccid condition of the uterus is therefore practically unattainable, and, we believe, wholly un- necessary in any case. ANESTHESIA IN NORMAL LABOR What are the advantages claimed for anesthesia in Normal Labor l Several of my correspondents say to me that they have never used anesthetics and much prefer the “old fashioned way.” This leads me to ask, “what benefits do the friends of anesthesia say are conferred on the parturient woman by its use, that any of us should seek to abandon the old way?” Briefly stated, they are these : The pains of child birth are abolished, and its dangers lessened. Is this true, and if so why is not the practice universal ? It is unsafe, say objectors, in this : (0) It may result in sudden death to the woman from drug poisoning. (b) It hazards the 11 life of both mother and child by retarding labor. (V) It increases the liability to hemorrhage. (d) It favors retention of the pla- centa. (