SUPPOSITORIES. RECTAL. VAGINAL. NASAL AURAL. URETHRAL. MANUFACTURED BY JOHN WYETH & BROTHER, Manufacturing Chemists, PHILADELPHIA, Entered according to Act of Congress in the year 1886, by John Wyeth & Brother, in the Office of the Librarian of Congress, at Washington, D. C. Wyeth’s Liquid Malt Extract. Containing all the Nutrient Properties of Malt, with the least possible amount of Alcohol. Fermented liquids prepared from malted grain, have been in use from the earliest times, and have always been highly prized for their strengthening and nutritive properties. Hitherto, however, the large amount of alcohol in proportion to nutritious matter contained in the malt liquors of commerce, has been a serious objection to their use, in many of the various forms of dyspeptic maladies, resulting from mal-nutrition, for which malt preparations are peculiarly adapted. Recognizing this fact, we have after numerous experiments, succeeded in pre- paring a liquid malt extract, possessing all the advantages of malt liquors, while it is not open to the objections, so frequently and justly urged against their use. It is especially adapted for administration to nursing mothers, and children, to patients suffering from nervous exhaustion, chilliness, etc., and, particularly, to those unable to digest starchy food. The diastase contained in our preparation of malt, renders such food immedi- ately soluble, by converting the'starch into malt-sugar and dextrine, in which form they can be readily assimilated by the system, thus creating animal heat, and aiding the formation of fat. Probably, its greatest value is, as a beverage, during lactation, as it not only supplies strength, to meet the unusual demands upon the system at that time, but improves the quality of the milk, by increasing the amount of sugar and phos- phates, nourishing the infant and sustaining the mother at the same time. In cases of consumptive tendencies, and in the latter stages of phthisis, it will be found to improve the appetite, and promote the assimilation of carbonaceous food, supplying the waste of elementary matter, fortifying the system, and enabling it to better resist the undermining effects of the disease. It also acts as a roborant in all cases of debility, and is the most valuable addition to the tonic and restora- tive treatment required in convalescence. Physicians will find, in many cases where Cod Liver Oil and Cream are inad- missible from want of digestive power, that the most susceptible patient can tolerate both, when given in conjunction with this liquid malt, if administered in small doses, gradually increased, as the tone of the stomach is strengthened. As it contains less than four per cent, of alcohol, it can be given to invalids- children, etc., without danger of secondary depressant effect, so frequently experi- enced from the administration of spirituous remedies; the ordinary dose of a wine, glassful representing less than forty grains of alcohol, and over one hundred and twenty-five grains of nutritious extractive matter, rich in diastase, preserved by our peculiar process of preparation; while in the malt-liquors, it is rendered inert by the boiling, to which they are subjected during manufacture. We claim that our Liquid Malt Extract will be found to contain all the nutritive virtues of the best malt-liquors, in a higher degree than any of the largely sold liquid malts, with which we have compared it, while it is free from the stimu- lating effect, which invariably follows their administration. Price, per dozen bottles, $3.00. JOHN WYETH & BROTHER, CHEMISTS, PHILADELPHIA. SUPPOSITORIES. URETHRAL. URETHRAL. NASAL NASAL. AURAL. AURAL. VAGINAL. VAGINAL. RECTAL. ACTUAL SIZES. RECTAL. THE extension of local methods in the treatment of diseases, both of systemic and local character, is a distinctive feature of modern therapeutics. This particular development received its chief stimulus from those pathological doctrines, which maintained the local character of most diseases, and of many which had long been held to rest on a constitutional basis. 2 In this development of local methods, the use of suppositories has grown pari passu with the necessities of practical therapeutics. We are convinced by multiplied evidence, that this mode of applying remedies is capable of immense extension as its advantages and utility are perceived. Suppositor- ies satisfy all the requirements of a suitable topical method. They are neat convenient, and efficient. They can be readily adapted to the various canals and outlets, so situated as to be reached by local or topical means, and their use. as a rule, can be accomplished by the patient without skilled assistance. Suppositories may be prepared for a merely local action; for systemic eflects; and for a combination of the two. They are especially efficient locally, as compared with solutions, in that the action may be maintained at a uniform rate, for a sufficient time. As compared with remedies, which introduced into the stomach, act after absorption, they have the advantage of a local impression in addition to the systemic eflects. Ihus, in the treatment of a nasal catarrh, the suppository employed for this purpose, may have a local action on the diseased membrane, and, also, an effect from the constitutional impression, the result of absorption. The eflects of suppositories comprehend a wide range of actions. As regards the local, they may be anodyne, antiseptic, alterant and astringent. As regards the systemic, they may be so compounded as to produce all of the eflects of which medicaments may be capable. The most superficial examina- tion suffices to demonstrate their multiform applicability, and their value as remedial agents To indicate the range of their uses, it will be most convenient to classify them in groups: 1st. Anodyne.—In many instances, the stomach is either intolerant of narcotics, or the patient has an invincible repugnance to taking them. Again, many anodynes act more efficiently by the rectum. This is the rule in in- flammatory and painful affections of the abdominal organs, for as all of the veins of the abdomen—except the renal—unite to form the portal, it is obvious that a local, as well as, a systemic action is obtained from diffusible anodynes put into the rectum. As the phenomenon called pain, has a complex mechanism, the remedies employed to relieve it, are more effective when they act upon the periphery of the nerve, as well as on the centre of conscious impressions. The mechanism of pain may be thus explained: The first element is, the irritation of the end organs (peripheral expansion) or trunk of the nerve affected ; 2, the trans- mission of the impulse, thus originating to the centre where it is translated into consciousness; B, the perception of the pain-sense, and 4, its reference outwardly to the point of origin, or to the periphery. An anodyne supposi- tory may act on the place of origin, on the lines of transmission, and on the centre of consciousness of the pain sense. An anodyne by the stomach, only acts on the last mentioned—on the centre of consciousness. As by combination, the efficiency of anodynes is increased, the defects of one supplied by the action of another, in preparing anodyne suppositories they may be made to contain various agents. Amongst the most useful of these are formulae, having the constituents indicated in the anodvne stoiid. 3 2nd. Hypnotic.—As a rule, hypnotics act more favorably when adminster od by the rectum, and the most convenient form for administration, is the sup- pository. The practitioner has a large list from which to select. Some are prepared with, and others without opium or morphine. When pain is the cause of wakefulness, no substitute for opium exists. When spasm is the source of pain—as, for example, after-pains—chloral becomes the most useful agent. The combination of opium and chloral, is peculiary efficient, but as they aid each others action, especially on the respiratory centre, their con- joint administration requires prudence. The addition of belladonna, confers on the combination of chloral and morphine, increased powers, whilst it lessens the danger of cardiac and respiratory depression. The whole consti- tutes an hypnotic and analgesic combination of remarkable efficiency, and is unequalled as a means of relief in cases of pain and wakefulness combined especially when the former is the cause of the latter. The other hypnotic combinations, are intended for wakefulness in cases in which opium and chloral are contra-indicated, either in consequence of the nature of their powers, or of idiosyncrasy on the part of the patient. They may prove of signal utility in cases of the insomnia of nervous affections and insanity, and the lack of cerebral repose in acute diseases. We may mention in illustration of the latter condition, the use of the hypnotic combination, No. 60, composed of chloral, monobromide of camphor, and liyoscyamine, in the delirium and wakefulness of acute pneumonia. rI he rectal suppository is advised in all cases, requiring the ajiodvne and hvpnotic combinations—even in pelvifc pain, and inflammation involving the uterus and its appendages. For whilst absorption by the rectum, may be as, uciive as by the stomach—in the case of’some remedies, more so—by the va- ginal mucous membrane which closely approaches in structure the common integument,it is less so. In general, for the multiform applications of anodynes and hypnotics, rectal suppositories are to be used. Exceptions to this rule will be indicated hereafter. For applications to other mucous surfaces—to the vagina, urethra, nares, fauces, auditory canal, etc., various Antiseptic, Alterant, and Astringent suppositories are required. I he part acted by minute organisms—microbes, morbific germs—in the production of diseases, is so important that topical applications containing an- tiseptics, are amongst the most valuable remedial measure®. Especially in catarrhal affections, common and specific, of the vagina, urethra and nares, do we find antiseptic and astringent suppositories unequalled in curative value. The advantages which they possess over solutions and other liquid prepara- tions are—facility of application, thoroughness and continuity of action. I he foregoing statements, general in character, regarding the therapeu- tical value of suppositories, will serve to indicate the conditions requiring them. To these special applications, we now direct attention. Pursuing the subject in the same order, we will commence with the anodyne and hypnotic groups of remedial agents, which may be applied with the best results in the form of suppositories. 4 In the various cerebral diseases requiring hypnotics and anodynes, the stomach is often in such an irritable condition as to be unable to retain remedies. Quite irrespective of the state of the stomach, however, supposi- tories may be preferable. In acute meningitis, acute mania, maniacal delirium, and delirium tremens, the stomach is either so irritable as to reject medicines or absorption by it of medicaments is so delayed or imperfect, as to render their actions uncertain, or the patient is in a mental condition which precludes swallowing. The hypodermic use of hypnotics and anodynes, lias been so often followed by disastrous over-action, or subsequently dangerous depression, that this mode of giving these remedies, is embarrassed by apprehensions of calamity in some form; hence, the comfort and safety of rectal supposi- tories, which will accomplish the same objects without the danger of sudden, excessive action, or alter failure of vital organs. Furthermore in these acute affections, the powers of life need support in the only mode in which it can be effectually rendered—by suitable nutriment. The stomach is already in a condition which interferes seriously with assimilation. When to this condi- tion of the organs, is added the depressing effects of the usual anodyne and narcotic medicines—their impression on the end-organs of the nerves of the mucous membrane—it may be readily conceived how necessary it is to employ medicaments free from these serious consequences. By means of the hyp- notic and anonyne combinations, represented in the formulae of the two groups, or other desired combinations, administered by the rectum twice or thrice a day, the best effects of which these remedies are capable, are produced, without any of the hindrances and ill-results with which their stomachal use is attended. Abundant clinical experience has now demonstrated that chloral, especially, is far safer and more efficient by the rectum than by the stomach. If not so conspicuously better in action by the same channel, opium, at feast to some extent, acts more kindly, whilst its positively depressing effect on the nerves of the stomach, and consequent interference with digestion, is thereby avoided. One of the great advantages possessed by the rectal suppositories, in the acute affections above mentioned, is the manner in which the force po- tential in the remedies thus used, is rendered actual. The force is not liberated suddenly, as when the hypodermic injection is practised, and expiring as sud- denly as given out, but is evenly and continuously evolved maintaining a uni- form effect. In that large and important group of diseases, in which wakefulness is due to pain or spasm, or both combined, the rectal use of some of the anodyne and hypnotic combinations offers us the best resource available. Iseuralgia, from affections of nerves, and from functional disturbance of some organ, as ovarian neuralgia, dvsmenorrhoea, etc.; the pain of inflammation of a serous membrane, as pleuritis and peritonitis; the pain caused by the passage of a calculus, as hepatic and renal colic, are all conditions in which the rectal sup- positorv is most efficient. Of all of these various states thus relieved, the best results are had from rectal suppositories in abdominal and pelvic pain, inflam- mation and spasm. Even in the affections strictly limited to the uterus and its appendages, of a painful and inflammatory character, rectal suppositories are greatly more efficient than vaginal. On the other hand, mere local lesions 5 of the vaginal and uterine mucous membrane, requiring astringent or anti- septic medication, are best treated by suppositories applied to the afieeted part. Probably, the most important suppositories, are those for the local treatment of aural, nasal, faucial, rectal, urethral and vaginal affections. Aural.—The aural suppository is adapted to the shape of the canal, and can be antiseptic, astringent, and anodyne as required. The formulae in- clude the usual remedies for these purposes and are adapted to the treatment of otorrhoea, polypi, eczema, etc. The anodyne combinations, relieve the pain of merely neuralgic affections, and inflammatory troubles involving the mid- dle and internal ear. In the application of aural suppositories, the auditory canal is gently wiped dry with the cotton wrapped probe, the suppository is then carefully in- serted, and is kept in place by maintaining the head in a suitable position, or by a plug of cotton, to which a cord may be attached to insure its easy with- drawal. The superiority of such an application over ordinary methods is quite obvious. All the world knows the dangers accompanying the use of the syringe, —except in skilled hands. Lotions and ointments nowr so much used, do not have the thoroughness and continuity of action, so desirable in the various affections of the auditory canals. Nasal.—What is true of aural, is equally, even in a higher degree, true of nasal affections. In the nasal passages, more than in any other cavities and outlets ot the body, are deposited morbific germs, the pollen of plants and other noxious substances, contained in the respired air. In accordance with the general law of etiology, the nasal mucous membrane, being most taxed in the performance of its functions, is most ready to yield to morbid actions. It is both the point of reception of disease-producing materials, and the seat of localised morbid processes. Through the fifth nerve and its nu- cleus, the nasal mucous membrane has wide-spread associations, with various organs, and is a link in the chain of numerous reflex disturbances. Nasal suppositories offer an admirable resource in the treatment of various local and svtemic affections. Catarrh, acute and chronic, ulceration, catarrhal and specific, polypus, asthma, hay-fever, etc., are the most common of these. To get the best effects from nasal suppositories, the position of the patient must be such as to permit the medicament to come in contact with the affected mucous membrane. When the suppository is placed in the anterior nares. the head should be inclined backward, the face uppermost, so that as the composi- tion melts, the materials flow over the whole surface; when the mucous is thick, tenacious, and adheres, a preliminary washing of the surface may be useful. With the douche, or post-nasal syringe, the passage can be cleansed with water containing some salt, or sal ammoniac. The nasal douche is re- sponsible for many cases of middle-ear disease and impaired hearing, and the post-nasal syringe, though far less dangerous, has done much mischief. The rhinologists, by topical methods in their own hands, avoid the evils wrought by the instruments above named, but it is obvious that treatment at their 6 hands involves expense and time. By means of properly prepared supposi- tories, the agents found most elective in the treatment of diseases of the nasal passages, can be applied by the patient with but occasional skilled assistance. After the suppository has had time to acton the mucous membrane, and before another one is introduced, tepid salt-solution can be used to cleanse the surface. Vaginal,.—It has already been pointed out that, in the treatment ol pel- vic pain and inflammation, of conditions of disease which can be reached only by medicaments after absorption—rectal suppositories are required. The vaginal mucous membrane does not have the structure to permit adequate ab- sorption of medicaments applied to it. However, in morbid states of the vaginal and uterine mucous membrane, suppositories perform a function which cannot be executed by any other form of topical application. The remedies applied to the vaginal mucous membrane may be antiseptic or germicide, as- tringent, alterative and anodyne. For specific catarrh, those suppositories containing corrosive sublimate, iodoform, the antiseptic oils, are especially effective. For simple catarrh, those containing tannin and iodoform, bismuth and tannin, hydrastis, boracic acid, benzoic acid, copaiba, etc., will be found useful. Before the suppository is placed in position, a hot water, or hot salt solu- tion douche should be taken, and also several hours after it has been intro- duced, allowing time for thorough action of the medicaments, the vaginal canal should be well irrigated. By this means, a clear surface is presented for the unobstructed action of the remedies used, and the products of their action removed. Urethral,.—The chief obstacle to the successful treatment of urethral affections, has been in the attempts to reach the affected surface. Before the advent of the modern topical methods, the only route available was bv the stomach, through the kidneys, into the urine; and the remedies found most useful belonged to a group of which Copaiba was the representa- tive. When the local origin and clinical characteristics of gonorrhoea came to be understood, topical treatment assumed greater importance, until at pre- sent the old stomachal remedies are but little used. Various kinds of medi- cated injections constitute the chief resources of the practical therapeutist, in the management of the various forms of urethritis, simple and specific. The obvious hindrances to the successful use of injections, consist tin he uncertainty as to the precise seat of the morbid action, in the complicated structure of the parts, in the protection to pathogenic organisms, afforded by the folds and crypts of the mucous membrane, and in the transient, fugitive impression, made on the disease by solutions injected. Properly prepared suppositories ob- viate these hindrances for the most part, and successfully combat the local morbid process. For specific urethritis or gonorrhoea, those suppositories containing the most active germicides are the most efficient—i. e., corrosive sublimate, iodo- form, resorcin, thymol, etc. When we have to deal with a simple catarrhal process, tannin, iodotannin, iodoform and hydrastis, are examples of remedies which have a curative action. To achieve good results, it is essential that the 7 medicament come in contact with the diseased part, and every microbe. The cylindrical suppository should be pushed down the canal, until it rests in the diseased area, where it should remain undisturbed until it has entirely melted. Both before and alter the introduction of the suppository, the urethra may be washed out with warm water, or warm salt-solution. The suppository and its remains should not be disturbed until all the effects of which it is capable, are accomplished. Forms.—The size and shape of suppositories are determined by the nature of the cavity to which applied. The doses of the medicaments are lixed by their character. Thus, remedies capable of absorption, as morphine and corrosive sublimate, must be apportioned as for stomachal administration, and those acting only locally, may be used in any quantity up to the capacity of tiie suppository. The period of their administration is determined by the character of the medicament, and the nature of the case. As a rule, two or three times a day will be proper and necessary; but, when the local action caused is considerable, it is best—generally speaking—to await the subsidence of the existing irrita- tion before starting a new one. In the local treatment of catarrh, this rule of practice is too often neglected, and a local action due to the medicament is confounded with the disease. The best time for administering a rectal suppository is at night on retir- ing, when the patient is not confined to the bed, or to the house. If bed-fast., they may be administered to the patient at any time, consistently with the state of the rectum. When the rectum is full of feces, it is necessary to empty it, and this may be readily accomplished by an enema of warm water. For convenience in ordering our Suppositories of the various forms and combinations, it is only necessary to specify the numbers; the prices quoted are for One Hundred Suppositories. They are put up in neat wooden boxes, each containing twenty suppositor- ies, and can readily be forwarded to any destination, by mail or express. The list of formula has been prepared with much care and research, having been submitted to several of our most eminent medical authorities, who have very cordially endorsed it, and to whom we are deeply indebted for many valuable suggestions as to doses and combinations. It embraces a great variety of for- mula, adapted to almost every symptom or emergency, and the utmost care, exact- ness and scrupulous attention to detail, so essential in preparing a class of agents containing such potent remedies, are exercised in their manufacture. Each suppository contains the exact amount of drug thoroughly and evenly in- corporated throughout the excipient, thus insuring the most prompt and effective action upon the economy. Our facilities for manufacturing special formula are unequalled, and any desired combination can be prepared in a few hours, upon the most reason- able terms. Quotations will be gladly furnished upon application. Those with whom we have_ no reoular correspondence, will please make remittance when sending order; unless this request is complied with, we will be compelled to decline forwarding. This is made imperative, owing to the fact that so many purchasers of small amounts pay little or no attention to the payment of such accounts Our prices are very moderate, and the small margin of profit necessitates our insisting upon the above reasonable request. JOHN WYETH & BROTHER, Chemists, Philadelphia. PRICE LIST and FORMULAE -OF SUPPOSITORIES Those with whom we have no regular correspondence, will please make remittance when sending order; unless this request is complied with, we will be compelled to decline forwarding. This is made imperative, owing to the fact that so many purchasers of small amounts, pay little or no attention to the payment of such accounts. Our prices are very moderate, and the small margin of profit necessitates our insisting upon the above reasonable request. ANODYNE. Price per 100. No. 16-— Morphinae Sulph. . . gr. No. 17.-$i-6o. Morphinae Sulph. . . gr. yz No. 18—«2.So. Morphinae Sulph. . . gr. I No. 19.—9Qcts. Morphinae Acetat. . . gr. No 20.—9°cts. Morphinae Acetat. . . gr. ]/% No. 21.—ti.2o. Morphinae Acetat. . . gr. %. No. 22.—#1.70. Morphinae Acetat. . . gr. No. 23.—$2.70. Morphinae Acetat. . . gr. I No. 24.-75 cts. Ext. Belladonnae, . . gr. % No. 25.-75 cts- Ext. Belladonnae, . . gr. yz No. 26.—80 cts. Ext. Belladonnae, . . gr. i No. 27.—3i.oo. Pulv. Opii, .... gr. 1 Pulv. Ipecacuanha;, . . gr. I No. 28—3130. Pulv. Opii, .... gr. 2 Pulv. Ipecacuanha;, . . gr. 2 No. 29.-90 cts. Pulv. Opii, . . • • gr- Ext. Belladonnae, . . gr. % Price per 100. No. 1— 75 cts. 01. Theobromse, No. 2.-75 cts. Pulv. Opii, . . . . gr. ]/% No. 3.-75 cts. Pulv. Opii, . . . . gr. £ No. 4.—75 cts. Pulv. Opii, . . . . gr. % No. 5.—80 cts. Pulv. Opii, . . . . gr. Yi No. 6.—90 cts. Pulv. Opii, .... gr. 1 No. 7.—#1.20. Pulv. Opii, . . . . gr. 2 No. 8.—$1.50. Pulv. Opii, . . . . gr- 3 No. 9.—$1.60. Pulv. Opii, . . . . gr. 4 No. 10.—80 cts. Aq. Ext. Opii, . . . gr. )■( No. 11.—9° cts. Aq. Ext. Opii, . . . gr. No. 12.—$1.20. Aq. Ext. Opii, . . . gr. I No. 13.-$ 1.50. Aq. Ext. Opii, . . . gr. 2 No. 14—9° cts. Morphina; Sulph. . . gr. -Jj No. 15.—9° cts. Morphinue Sulph. . . gr. y% 9 Price per 100 No. 30.—9octs. Pulv. Opii, .... gr. I Ext. Belladonna, . . gr. % No. 31.—$1.30. Pulv. Opii, .... gr. 2 Ext. Belladonna', . . gr. No 32.—$1.50 Pulv. Opii, . . . . gr. 3 Ext. Belladonnas, . . gr. ]/2 No. 33.—9octs. Aq. Ext. Opii, . . . gr. yz Ext. Belladonna, . . gr. No. 34.—$1.30. Aq. Ext Opii, . . . gr. I Ext. Belladonna, . . gr. */2 No. 35.- $ 1-50. Aq. Ext. Opii, . . . gr. \'/z Ext. Belladonna, . . gr. J No. 36.—$1.80. Aq. Ext. Opii, . . . gr. 2 Ext. Belladonna, . . gr. y No. 37.—£ I 80 Aq. Ext. Opii, . . . gr. 2 Ext. Belladonna, . . gr. i No. 38.—$2.00. Aq. Ext. Opii, . . . gr. Ext. Belladonna, . . gr. i No. 39.—$1.30. Ext. Hyoscyami, . . gr. 3 No. 40.—$170. Ext. Hyoscyami, . . gr. 5 No. 41.—$150. Ext. Hyoscyami, . . gr. 2 Aq. Ext. Opii, . . . gr. I No. 42.—$1.90. Ext. Hyoscyami, . . gr. 4 Aq. Ext. Opii, . . , gr. 1 Price per 100. No. 43.—9° cts. Ext. Opii, . . . . gr. Ext. Belladonna, . . gr. y Ext. Cocae, . . . gr. l/2 No 44.—$i.6o. Ext. Opii, gr. x/2 Ext. Belladonnae, . . gr. I Ext. Cocae, . . gr. 2 No. 45. —90 cts. Morphinae Sulph. . . gr. y Atropinae Sulph. . . gr. No. 46.—$1.80. Morphinae Sulph. . . «gr. y2 Atropinae Sulph. . . gr. No. 47.—$2.50. Morphinae Sulph. . . gr. J Atropinae Sulph. . . gr. Cocaina; Hydrochlor. . . gr. y No. 48.—$3.00. Morphina; Sulph. . . gr. l/2 Atropina; Sulph. . . gr. Cocaina; Hydrochlor. . . gr. £ No. 49.—#2.50. Morphinae Sulph. . . gr. J- Atropinae Sulph. , . . gr. T^5 Cocaina; Hydrochlor. . . gr. y Ext. Cannabis Indicae, . gr. x/2 No. 50.—$7.00. Morphinae Sulph. . . gr. l/2 Atropinae Sulph. . . gr. Cocaina; Hydrochlor . . gr. £ Ext. Cannabis Indicae, . gr. \ No. 51.—$5.00. Codeina;, . . . . gr. I Ext. Hyoscyami, . . gr. 1 Ext. Cannabis Indicae, . gr. y2 No. 52.—$12.00. Codeinae, . . . . gr. 2 Ext. Hyoscyami, . . gr. 2 Ext. Cannabis Indicae, . gr. 2 10 Price per 100. No. 53.—5 1.50. Ext. Cannabis Indicae, . gr. y2 Ext. Hyoscyami, . . gr. i Ext. Cocae, . . . gr. 2 No. 54—$2.50. Ext. Cannabis Indicae, . gr. 2 Ext. Hyoscyami, . . gr. 4 Ext. Cocae, . . . gr. 5 HYPNOTIC. No. 55.—$2.00. Chloral Ilydrat. . . gr. 10 Atropinae Sulph. . . gr. Morphinae Sulph. . . gr. i No. 56.—£4-00. Chloral Hydrat. . . gr. 30 Atropinae Sulph. . . gr. T^5 Morphinae Sulph. . . gr. '/2 No. 57.—$10.00. Urethane, . . . . gr. 10 No. 58.—5i4-oo. Urethane, . . . . gr. 15 No. 59.—#4-oo. Chloral Hydrat. . . gr. 15 Camphor Monobromat. . gr. 5 Hyoscyamin. Hydrochlor. . gr. No. 60— $5.°o. Chloral Hydrat. . . gr. 20 Camphor Monobromat. . gr. 10 Hyoscyamin. Hydrochlor. . gr. No. 61—52.50. Chloral Hydrat. . • gr- 15 Morphinae Sulph. . . gr Atropinae Sulph. . . • gr- yy^ No. 62.-54 00. Chloral Hydrat. . . gr- 20 Morphinae Sulph. . . gr- Yz Atropinae Sulph. . . gr- yjy Price per 100. No. 63.—$2.00. Ext. Opii gr. Ext. Cannabis Indicoe, . gr. i Lupulini, . . . . gr. 5 Ext. Hyoscyami, . . gr. 1 No. 64.—#2.50. Ext. Opii gr. 1 Ext. Cannabis Indicoe, . gr. 2 Lupulini, . . . . gr. 15 Ext. Hyoscyami, . . gr. 2 No. 65.—$ 1.80. Ext. Cannabis Indicoe, . gr. l/2 Lupulini, . . . . gr. 5 Ext. Hyoscyami, . . gr. 1 Camphor Monobromat. . gr. 2 No. 66.—£2.50. Ext. Cannabis Indicoe, . gr. 1 Lupulini, . . . . gr. 15 Ext. Hyoscyami, . . gr. 2 Camphor Monobromat. . gr. 5 No. 67.—£9-00. Hyoscinoe Hydrobromat. . gr. Codeinae, . . . . gr. 1 Lupulini, . . . . gr. 5 No. 68.—$ 15-00. Hyoscinoe Hydrobromat. . gr. Codeinoe, . . . . gr. 2 Lupulini, . . . . gr. 10 ANTISEPTIC. No. 69.—#2.50. Iodoformi, . . . . gr. 2 Thymol, .... gr. 1 Resorcin gr. 5 No. 70.-$6.00. Iodoformi, . . . . gr. 5 Thymol gr. 1 Resorcin gr. 10 11 Price per lOO. No. 71.— £2.50. Iodoformi, .... gr. 5 Acid. Tannic. . . . gr. 10 No. 72-.#3-25- Iodoformi, . . . . gr. 5 Acid. Tannic. . . . gr. 20 No. 73.—*2.25. Acid. Boric. . . . gr. 5 Thymol gr. 2 Ol. Eucalypti, . . . M. 1 No. 74.—$3.50. Acid. Boric. . . . gr. 10 Thymol. . . . . gr. 1 Ol. Eucalypti, . . . M. 3 No. 75.—#400. Acid. Benzoic. . . . gr. 5 Hydrarg. Chlor. Cor. . . gr. -fa Resorcin. . . . . gr. 10 No. 76.—$4 50. Acid. Benzoic. . . . gr. 10 Hydrarg. Chlor. Cor. . . gr. Resorcin. . . . . gr. 10 No. 77.—$1.80. Kapthalini, . . . gr. 2 Sodii Biborat. gr. 10 Hydrarg. Chlor. Cor. . . gr. Ol. Eucalypti, . . . M. 2 No. 78.-$ 1.80. Napthalini, . . . gr. 3 Sodii Biborat. . . . gr. 10 Hydrarg. Chlor. Cor. . . gr. Ol. Eucalypti, . . . M. 2 No. 79.—$2.25. Acid. Salicylic. . . . gr. 5 Acid. Boric. ... . gr. 5 Thymol gr. 2 No. 80.—$3 00. Acid. Salicylic. . . . gr. 10 Acid. Boric. . . . gr. 10 Thymol gr. 5 Price per 100. No. 81.—$1.20. Iodoformi, . . . . gr. 2 No. 82—$1.40. Iodoformi, . . . . gi. 3 No. 83—80 cts. Acid. Boric. . . • gr. 5 ASTRINGENT. No. 84.—$i.2o. Pulv. Opii gr. 1 Acid. Tannic. . . . gr. 2 No. 85.—$1.50- Pulv. Opii, .... gr. 2 Acid. Tannic. . . . gr. 2 No. 86.—$i.4°- Pulv. Opii gr. 1 Acid. Tannic. . . . gr. 5 No. 87.-$i-7°- Pulv. Ppii, .... gr. 2 Acid. Tannic. . . . gr. 5 No. 88.—$1.00. Pulv. Opii, .... gr. I Plumbi Acetat. . . . gr. 2 No. 89—$1.3°. Pulv. Opii, . . . . gr- 2 Plumbi Acetat. . . . gr. 2 No. 90.—$J.oo. Pulv. Opii, . . . . gr. 1 Plumbi Acetat. . . . gr. 5 No. 91.—$1.30. Pulv. Opii, .... gr. 2 Plumbi Acetat. . . . gr. 5 No. 92.-75 cts- Ext. Belladonnae, . . gr. % Plumbi Acetat. . . . gr. il/j No. 93.—80 cts. Ext. Belladonnae, . . gr. Plumbi Acetat. . . . gr. 3 No. 94.—90 cts. Acid. Tannic. . . . gr. 2 No. 95.—$1.10. Acid. Tannic. . . . gr. 5 No 96—$1.80. Acid. Tannic. . . . gr. 10 12 Price per 100. 0. 97.—80 cts. Ext. Stramonii, . . . gr. i Plumbi Acetat. . . . gr. 2 No. 98.—9° cts. Ext. Stramonii, . gr. y2 Acid. Tannic, . . ' . gr. y2 Plumbi Carbonat. . . gr. i Liquor Plumbi Subacetat. . M. 2 Creasoti, . . . . M. y2 No. 99.—$200. Plumbi Iodidi, . . . gr. 3 Ext. Belladonna;, . . gr. y2 Morphinae Sul] h. . . gr. Acid. Tannic. . . . gr. 5 No. 100.—$ 1 20. Ext. Stramonii, . . . gr. 1 Acid. Tannic. . . . gr. 5 No. 101— #1.00. Ext. Krameriae, . . . gr. 3 No. 102.-^120. Ext. Krameriae, . . . gr. 5 No. 103—#1.80. Ext. Krameriae, . . . gr. 10 No. 104.-^1.20. Acid. Tannic. . . . gr. 5 Acid. Gallic. . . . gr. 2 Ext. Krameriae, . . . gr. 1 No. 105.—®2.4o. Acid. Tannic. . . „ gr. 10 Ext. Krameriae, . . . gr. 5 Acid. Gallic. . . . gr. 4 No. 106.—^2.oo. Acid. Gallic. . . gr. 2 Ext. Ergotae, . . . gr. 5 Digitalis, . . . . gr. I No. 107.-^2.50. Acid. Gallic. . . . gr. 5 Ext. Ergotae, . . . gr. 10 Digitalis, . . . . gr. 2 [ Prioe per 100. No. 108 —*2.25. Bismuthi Subnitrat. . . gr. io Acid. Tannic. . . . gr- 5 No. 109.—#3-50. Bismuthi Subnitrat. . . gr. 20 Acid. Tannic. . . . gr. 10 No. 110.-^2.25. Bismuthi Subnitrat. . gr. 10 Thymol. . . . . gr. 2 No. lll.-J3.50. Bismuthi Subnitrat. . . gr. 20 Thymol. . . . . gr. I NO. 112—$2.20. Acid. Tannic. . . . gr. 5 Eucalyptol. . . . M. 1 Iodoformi, . . . gr. 2 No. 113.—$300. Acid. Tannic. . . . gr. 20 Eucalyptol. . . . M. 2 Iodoformi, . . . . gr. 5 No. 114.—#1.80. Acid. Tannic. . . . gr. 5 Bismuthi Subnitrat. . . gr. 5 Hydrarg. Chlor. Cor. . . gr. No. 115.-^2.50. Acid. Tannic. . . . gr. 10 Bismuthi Subnitrat. . . gr. 10 Hydrarg. Chlor. Cor. . . gr. VAGINAL. No. 116.—#300. Iodoformi. . . . gr. 5 Hydrarg. Chlor. Cor. . . gr. fa No. 117.- $4-oo. Iodoformi. . . . gr. 10 Hydrarg. Chlor. Cor. . . gr. fa No. 118.— $4.00. Iodoformi. . . . gr. 5 Acid. Tannic. . . . gr. 15, 13 Price per 100. No. 119—#4-5°- Iodoformi. . . . gr. 5 Acid. Tannic. . . . gr. 30 NO. 120.—#8.00. Copaibse, . . . . gr. 30 Acid. Tannic. . . . gr. 20 Ol. Caryophylli, . . . M. 1 No. 121.-^5-00. Copaibse, . . . . gr. 15 Acid. Tannic. . . . gr. 10 Ol. Caryophylli, . . . M. 2 No. 122.-J5S5.oo. Acid. Tannic. . . . gr. 40 Acid. Boric. . . . gr. 5 No. 123.-^5-00. Acid. Tannic. . . . gr. 40 Acid. Boric. . . . gr. 10 No. 124.—#4.00. Acid. Salicylic. . . . gr. 10 Acid. Boric. . . . gr. 5 Acid. Tannic. . . . gr. 20 No. 125.-^4.50- Acid. Salicylic. . . . gr. 15 Acid. Boric. . . . gr. 5 Acid. Tannic. . . . gr. 20 No. 126 —3500. Bismuthi Subnitrat. . . gr. 20 Acid. Tannic. . . . gr. 20 NO. 127.-36.50. Bismuthi Subnitrat. . . gr. 40 Acid. Tannic. . . . gr. 20 No. 128.—33.50. Potassii Chlorat. . . . gr. 10 Potassii Bromidi, . . gr. 15 Acid. Tannic. . . _ gr 2Q No. 129.—3450. Potassii Chlorat. . . . gr. 15 Potassii Bromidi, . , gr 2o Acid. Tannic. . . . gr. 30 Prioe per 100. No. 130—3 2.00. Plumbi Nitrat. . . . gr. 2 Plumbi Acetat. . . . gr. 5 No. 131—$2.25. Plumbi Nitrat. . . . gr. 5 Plumbi Acetat. . . . gr. 10 No. 132—#3-5°- Bismuthi Subcarb. . . gr. 10 Plumbi Carbonat. . . gr. 5 Eucalyptol. . . . M. 2 No. 133.—#4.00. Bismuthi Subcarb. . . gr. 20 Plumbi Carbonat. . . gr. 10 Eucalyptol. . . . M. 2 No. 134.—#3.25. Zinci Oxidi, . . . gr. 5 Zinci Sulphocarbolat. . . gr. 10 Thymol. . . . . gr. 2 No. 135.—$5.00. Zinci Oxidi, . . . gr. 10 Zinci Sulphocarbolat. . . gr. 20 Thymol, . . . . gr. 5 No. 136.—#5-50. Resorcin gr. 5 Bismuthi Subnitrat. . . gr. 20 Salicini,_ . . . . gr. 10 No. 137.—$8.oo. Resorcin. ... gr. 10 Bismuthi Subnitrat. . . gr. 30 Salicini, . . . . gr. 10 No. 138— 5900. Cocainae Hydrochlorat. . gr. )£ Salicini, . . . . gr. 20 No. 139 —$15.00. Cocainas Hydrochlorat. . gr. 1 Salicini, .... gr. 40 14 URETHRAL. Price per IGtt No. 152.-li.8o. Salicini, . . . . gr. 2 Copaiba; M. 2 01. Cubeba;, . . . M. i No. 153.—^i.90- Salicini, .... gr. 3 Copaibae, . . . . M. 2 01. Cubeba;, . . . M, 1 No. 154.—90 cts. Zinci Sulph. . . . gr. I Cupri Sulph. . . . gr. 1 No- 155—9° cts. Zinci Sulph. . . . gr. 3 Cupri Sulph. . . . gr. 1 No. 156.-^150. Iodoformi. . . gr. 2 Acid. Tannic. . . gr. I Thymol. . . . gr. No. 157.—#1.60. Iodoformi. . . . gr. 2 Acid. Tannic. . . . gr. 2 Thymol gr. AURAL. No. 158.-75 cts. Bismuthi Subnitrat. . . gr. I Acid. Benzoic. . . . gr. 1 No. 159.-9° cts. Bismuthi Subnitrat. . . gr. 2 Acid. Benzoic. . . . gr. 1 No. 160.—$ 1.20. Iodoformi. . ■ . . gr. 1 Acid. Tannic. . . . gr. 2 No. 161.—iPi.oc. Iodoformi. . . . gr. 1 Acid. Tannic. . . . gr. 3 No. 162.—60 cts. Acid. Boric. . . . gr. Acid. Tannic. . . . gr. I Price per 100. No. 140.—#1.20. Ilydrarg. Chlor. Cor. . . gr. Hydrarg. Chlor. Mite, . gr. i Ol. Eucalypti, . . . M. i No. 141.—#1-25. Hydrarg. Chlor. Cor. . . gr. Hydrarg. Chlor. Mite, . gr. 5 Ol. Eucalypti, . . . M. 1 No. 142—#100. Bismuthi Subcarb. . . gr. 2 Plumbi Carb. . . gr. 1 No. 143.-# 1.20. Bismuthi Subcarb. . . gr. 3 Plumbi Carb. . . . gr. 1 No. 144.—#1.25. Copaiba, . . . . M. 2 Acid. Tannic. . . . gr. 2 No. 145.-#i-60. Copaiba;, . . . . M. 3 Acid. Tannic. . . . gr. 3 No. 146.-#160. Copaiba*, . . . . M. 2 Bismuthi Subnitrat. . . gr. 3 No. 147— #2od. Copaiba, . . . . M. 3 Bismuthi Subnitrat. . . gr. 5 No. 148.—9°cts. Hydrarg. Chlor. Mite, . gr. 1 Potassii Chlorat. . . . gr. I No- 149.—#1-20. Hydrarg. Chlor. Mite, . gr. 2 Potassii Chlorat. . . . gr. 3 No. 150.— # 1.80. Hydrastini, . . . gr. Salicini, . . . . gr. 2 No. 151 —#2.50. Hydrastini, . . . gr. 1 Salicini, .... gr. 3 15 Price per 100. No. 163—7° cts. Acid. Boric. . . . gr. i Acid. Tannic. . . . gr. 2 No. 164.—60 cts. Zinci Sulphocarbolat. . . gr. I Zinci Sulph. . . . gr. i No. 165.—65 cts. Zinci Sulphocarbolat. . . gr. 2 Zinci Sulph. . . . gr. 1 No. 166.-75 cts- Hydrarg. Oxidi Flavi, . gr. 1 No. 167.—#1.00. Hydrarg. Oxidi F'lavi, . • gr. 3 No. 168.—65 cts. Hydrarg. Chlor. Cor. . . gr. Hydrarg. Chlor. Mite, . gr. 1 No. 169.-7° cts. Hydrarg. Chlor. Cor. . . gr. Hydrarg. Chlor. Mite, . gr. 2 No. 170.-75 cts. Acid. Salicylic. . . . gr. 1 Acid. Boric. . . . gr. Acid. Tannic. . . . gr. 1 No. 171 —9° cts. Acid. Salicylic. . . . gr. 2 Acid. Boric. . . . gr. 1 Acid. Tannic. . . . gr. 2 No. 172.—$i. 20. Thymol. . . . . gr. yz Eucalyptol. . . . M. 1 Chloral Hydrat. . . . gr. 1 NO. 173.—$ 1.80. Thymol. . . . . gr. 1 Eucalyptol. . . . M. 2 Chloral Hydrat. . . . gr. 1 No. 174.-9° Cts. Morphinae Sulph. . . gr. yfc Atropinae Sulph, . . gr. Price per 100. No. 175.—31.50. Morphinx Sulph. . . gr. Atropinx Sulph. . . gr. ; * 0 No. 176 — $3.50. Cocainx Hydrochlorat. . gr. 1 Morphinx Sulph. . . gr. % No. 177—314-00. Cocainx Hydrochlorat. . gr. I Morphinx- Sulph. . . gr. | No. 178 —3330. Cocainx Hydrochlorat. . gr. I Potassii Chlorat. . . . gr. 1 No. 179.—$12.00. Cocainx Hydrochlorat. . gr. 1 Potassii Chlorat. . . . gr- 3 No. 180.—80 cts. Morphinx Sulph. . . gr. % Acid. Tannic. . . . gr. 1 No. 181.—31.50. Morphinx Sulph. . . gr. | Acid. Tannic. . . . gr. 2 No. 182.-37-00. Morphinx Sulph. . . gr. Atropinx Sulph. . . gr. TJj0 Cocainx Hydrochlor. . . gr, £ NASAL. No. 183.-90 cts. Potassii Chlorat. . . . gr. 2 Thymol. . . . . gr. i No. 184.—9° cts. Potassii Chlorat. . . . gr. 3 Thymol. . . . . gr. £ No. 185.-3i.oo. Bismuthi Subnitrat. . . gr. 1 Euca'yptol. . . . M. 1 No. 186.—3i.6o. Bismuthi Subnitrat. . . gr. 3 Eucalyptol. . . . M. 1 No. 187.—31.20. Iodoformi. . . . gr. I Thymol gr. i. 16 Price per 100- No. 188.—$i.oo. Iodoformi. • . . gr. I Acid. Tannic. . . . gr. 2 No. 189—$1-20. Iodoformi. . . . gr. 2 Acid. Tannic. . . . gr. 2 No. 190— 60 cts. Hydrarg. Chlor. Cor. . . gr. Potassii Chlorat. . . . gr. I No. 191—65 cts. Hydrarg. Chlor. Cor. . . gr. Potassii Chlorat. . . . gr. 2 No. 192.-9° cts. Acid. Boric. . . . gr. 1 Sodii Biborat, . . . gr. 2 Thymol gr. \ No. 193.—^i.io. Acid. Boric. . . . gr. 1 Sodii Biborat, . . . gr. 2 Thymol . . . . gr. j No. 194.—*1.00. Acid. Benzoic. . . . gr. 1 Iodoformi. . . . gr. 1 Hydrarg. Chlor. Cor, . . gr. No. 195.—*4.00. Acid. Benzoic. . . . gr. 2 Iodoformi. . . . gr. 1 Hydrarg. Chlor. Cor. . . gr. Cocainse Hydrochlorat. . gr. £ No. 196.-*i2.oo. Cocainse Hydrochlor. . . gr. 1 No. 197 —$3.50. Cocainae Hydrochlor. . . gr. | Morphinse Sulph. . . gr. Price per 100. No. 198.—$12.00. Cocainae Hydrochlor. . gr. i Morphinae Sulph. . . gr. J. No. 199.—$3.50. Cocainae Hydrochlor. . gr. Morphinae Sulph. . . gr. Atropinae Sulph. . . gr, 2 No. 200.—$12.00. Cocainae Hydrochlor. . gr. I Morphinae Sulph. . . gr Atropinae Sulph. . . gr. . No. 201.—$3-5°- Cocainae Hydrochlor. . gr. Eucalyptol. . . . M. I Thymol. . . . . gr. | No. 202.—$12.00. Cocainae Hydrochlor. . gr. I Eucalyptol. . . . M. 2 Thymol. . . . . gr. i No. 203.-9° cts. Morphinae Sulph. . . gr. Zinci Oxidi, . . . gr. 2 No. 204.—$i 6o. Morphinae Sulph. . . gr. i- Zinci Oxidi, . . . gr. I Bismuthi Subnitrat. . . gr. 2 No. 205.—$4 20. Bismuthi Subnitrat. . . gr. 3 Cocainae Hydrochlor. . . gr. i No. 206—$425. Acid. Tannic. ... gr. ij Iodoformi. . . . gr. i Cocainae Hydrochlor, . . gr. JOHN WYETH & BROTHER, Philadelphia. ERRATUM. Formula No. 193 should read, Acid. Boric., . . gr. 2 Sodii Biborat., . . gr. 3 Thymol, . . . gr. 1 17 WINE OF TAR. Formula of Prof. Samuel Jackson, late professor of the Theory and Practice of Medicine, University of Pennsylvania. The formula for the Wine of Tar, together with the method by which the best product can be obtained, was furnished us quite thirty years since, by Dr. Samuel Jackson, a celebrated Professor in the University of Pennsylvania .viedi- cal College. He prescribed it largely, either alone, or in combination, in every case of Pulmonary disease—in phthisis, chronic bronchitis, and the catarrhs of the broncho pulmonary tract. He also, gave it freely, and with much success, in the catarrhal affections of the mucous membranes in general, and especially, besides the pulmonary—in those of the genito-urinary passages. Dr. Jackson’s success in the use ot this remedy, induced some of the most eminent practitioners of the time—amongst whom we particularly remember, Professor William Pepper and Dr. William W. Gerhard—to begin its employment in the same affections, and they had equally good results. Notwith- standing the remarkable success achieved by the Wine of Tar, newer and more popular if less efficient remedies, for a time displaced it, but, in the course of those revolutions of professional favor, by no means uncommon, it has again assumed its rightful place as a remedy. The recent developments in the pathogeny of phthisis, and in the therapeutics of catarrhal affections, have demonstrated the utility of remedies possessed of the antiseptic powers, and the stimulating and nutritive properties of the Wine of Tar, as made by us. In a complexus of symptoms, by no means rare—bronchial and stomachal catarrh combined—the Wine of Tar has special efficacy; it moderates the cough, promotes expectoration, and, at the same time, allays nausea, and increases appe- tite and digestive power. Practical physicians need hardly be told, how ordinary cough remedies and expectorants fail under such circumstances; the agents that relieve the cough, disorder the stomach. It is a misfortune of the action of most remedies used against cough, that they are apt to distress the stomach, and impair the appetite. As, in all cases of chronic cough, it is of vital importance to maintain the nutrition, the value of a remedy acting as our Wine of Tar, can be readily appreciated. There is another class of cases, in which the Wine of Tar is capable of effect- ing very great relief;—cases of bronchitis, in which there is coincident catarrh of the urinary passages. In the latter affections alone, whether examples of pyone- phrosis, or vesical catarrh, it must be ranked amongst the most efficient remedies. In irritability of the bladder, and in some instances of urinary incontinence, requir- ing the exhibition of a stimulating remedy, it may be expected to do good. When the inhalation of the vapor of Tar is indicated, our Wine of Tar will be found the most effective and agreeable way to administer it, either with an atomizer, or by an inhaler. As an Expectorant, the adult dose is a dessertspoonful every three or four hours. As a Tonic, take a tablespoonful an hour before meals, the physician graduating: the dose for children, according: to age. Pome practitioners, claiming that the gradual increase of the dose is an advantage, prescribe double the above dose to patients who have already taken it, for a considerable time. DIRECTIONS. Price, per dozen pints, JOHN WYETH & BROTHER. $4.00. CHEMISTS, PHILADELPHIA. 18 Fluid Extract of Ergot. In presenting to the Medical Profession our Fluid Extract of Ergot, we fully realize the responsibility assumed, in making the representations we do in regard to our preparation. No article in the Materia Medica has so often disappointed the practitioner, and scarcely any drug is more susceptible of change, deterioration, and in time, to become entirely inert. We have hesitated to ask the unconditional endorsement of the Profession, until we had fully demonstrated for ourselves, the value of the Fluid Extract we make, but, after nearly ten years continued evidence of its successful use in the hands of medical men throughout the country, during which time, we have manufactured many thousands of pounds, we confidently claim for it, a value and efficacy superior to any other preparation of this drug. The menstruum used, is that best adapted for extracting all the active matter, and retaining its full power. Each minim represents one grain of the freshly powdered drug. It is entirely free from acid, and can be used subcutaneously, without irritation in most cases, having in this respect, a great advantage over the watery solutions, which decompose very rapidly. Our menstruum is simply Water, Alcohol and Glycerine, no heat whatever being used in its manufacture. Since adopting this formula, a number of valuable papers from foreign authorities have endorsed our views. Our large operations and long experience enable us to select the choicest importations of Ergot as offered, thus insuring material of unexceptionable quality. It will always give us pleasure, to send samples to any member of the Profession who may desire to test its value, or confirm our representations, by experiment in private practice, or in institutions with which he may be connected. Our list of Fluid Extracts embraces all those generally manufactured. We claim for them, careful selection of Crude Material, intelligent and accurate manipulation, and conscientious exactness in every detail. Complete lists will be furnished upon application. JOHN WYETH & BROTHER. CHEMISTS, PHILADELPHIA. 19 Spencer’s Chloramine Pastilles For the cure of Hoarseness, Sore Throat, Bronchitis, Cough, and other Derangements of the Breathing Tubes and Lungs. These are absolutely, the most pleasant and efficacious Pastilles yet introduced, for the relief of the various disorders of the respiratory organs, induced by the changeableness of the climate. As the name implies, the principal ingredient of these Pastilles is Muriate of Ammonia, which is itself a valuable remedy for the cure of many bronchial affec- tions, and is here associated with other medicines, having a powerful calmative influence, over the mucous membrane of the respiratory tubes, thereby adding effectiveness to the Pastilles, and extending their range of usefulness. Influenza, Hoarseness, Soreness of Throat, or any irritation of the throat arising from cold, will almost invariably be relieved by the use of a few of the Tablets. kor clearing and strengthening the voice, they will be found very serviceable. Direction's.—Allow one of the Tablets at a time, to dissolve slowly in the mouth, taking from eight to twelve during twenty-four hours. The Spencer Chloramine Pastilles were largely prescribed by Physicians, a few years since, in Philadelphia and vicinity, the speedy relief from their use giving them greater popularity, wherever known, than any lozenge prepared, for Coughs, Colds, Inflammation of the mucous membranes, etc., etc. Doctors and patients have united in commendation of their effect. In our judgment, the combination is an improvement upon the ingredients in Jackson's Ammonia Lozenges. The formula was devised, we understand, by Mr. Lenher, an Opeiative Chemist, held in high esteem in this city, for many years; certainly, he has united, most judiciously, Chloride of Ammonium and Chloride of Potassium, Extracts of Dulcamara and Ilyoscyamus, as calmative anodynes, the pectoral Balsams, Tolu and Peru, with Senega, Squills and a minimum of Ipecac. In fact, we think more highly of it, than any prescription known to us, our long experience making us familiar with the composition of all this class of remedies. We have no hesitation in endorsing it unreservedly, as likely to prove of more immediate benefit, than any of the popular cough remedies, being free from anv of the many objections attending the use of Syrups and Lozenges, that so often derange the digestive organs, nauseate, and destroy the appetite, ihe effect in these cases, being due, usually, to an excess of morphia, tartar emetic or both, doin" harm rather than good. Owing to Mr. Spen'cer relinquishing the drug business, and the death of Mr. Lenher, we were induced to purchase the formula and right to manufacture, our appliances and experience enabling us to prepare these Pastilles, so as to prove more permanent, than when manufactured by former proprietors. JOHN WYETH & BROTHER, CHEMISTS, Philadelphia. 20 COMPRESSED LOZENGES OF THE UNITED STATES PHARMACOPCEIA, BRITISH PHARMACOPCEIA, LONDON THROAT HOSPITAL, (Dr. MorellMackenzie) AND UNOFFICINAL FORMULA. The kind favor and cordial endorsement, extended by the Drug Trade and Medical Men to our Compressed Pills, Compressed Tablets and Compressed Hypodermic Tablets, have induced us to extend our line, and to manufacture the above class of preparations, which are in more general popular demand than almost any other, containing active medicinal ingredients. We do not desire that this- series of preparations, as prepared by us, shall be confused with the numerous confections and pasty mixtures, so much in vogue. Our Lozenges are intended, strictly and exclusively, for medicinal pur- poses. They embrace all those authorized by the United States Pharmacopoeia, British Pharmacopoeia, the London Hospital for Dis- eases of the Throat, and a number of unofficinal combinations that have long been recognized by the profession, as almost standard remedial agents, as well as having a wide-spread and popular demand. Our novel and peculiar process of compressing from perfectly dry powders, insures permanency and freedom from atmospheric influ- ences, so apt to affect and render unsightly, these preparations, as generally manufactured; this, together with the perfection of our machinery, enables us to produce a Lozenge of exact weight, accu- racy of dose, beauty of finish, and thorough admixture of active medicinal ingredients, which must commend them to all, and supply a want long felt. We feel assured from the favor already evinced, wherever we have shown our Lozenges, they will receive the cordial endorsement of the profession, and consumers generally. Price List, with formula, will be sent by mail to those who desire it. JOHN WYETH & BROTHER. PHILADELPHIA. CHEMISTS, HYPODERMIC TABLETS Price-List of Soluble Compressed The following formulae and combinations embrace all those in general request. Others will be added, as the demands of the profession warrant their manufacture. We claim for our Hypodermic Tablets: Absolute accuracy of dose. Ready and entire solubility. Perfect preservation of the drug. Their convenience and utility will at once be apparent on examination. EXACT SIZE OP TUBE. No. I Morphia Sulphas 1-2 grain, Soda Sulphas 1-4 grain, $2.50 2 Morphia Sulphas 1-3 grain, Soda Sulphas 1-4 grain, 2.00 “ 3 Morphia Sulphas 1-4 grain, Soda Sulphas 1-4 grain, 2.00 “ 4 Morphia Sulphas 1-6 grain, Soda Sulphas 1-4 grain, 2.00 “ 5 Morphia Sulphas 1-8 grain, Soda Sulphas 1-4 grain, 2.00 “ 6 Morphia Sulphas 1-12 grain, Soda Sulphas 1-4 grain, 2.00 ■“ 7 Morphia Sulphas 1-2 grain, Atropia Sulphas 1-100 grain, Soda Sulphas 1-4 grain, 2.50 “ 8 Morphia Sulphas 1-3 grain, Atropia Sulphas 1-120 grain, Soda Sulphas 1-4 grain, 2.00 41 9 Morphia Sulphas 1-4 grain, Atropia Sulphas 1-150 grain, Soda Sulphas 1-4 grain, 2.00 44 10 Morphia Sulphas J-6 grain, Atropia Sulphas 1-180 grain, Soda Sulphas 1-4 grain, 2.00 44 11 Morphia Sulphas 1-8 grain, Atropia Sulphas 1-200 grain, Soda Sulphas 1-4 grain, 2.00 ■“ 12 Morphia Sulphas 1-12 grain, Atropia Sulphas 1-250 grain, Soda Sulphas 1-4 grain, 2.00 44 13 Atropia Sulphas 1-60 grain, Soda Sulphas 1-4 grain, 1.50 4‘ 14 Atropia Sulphas 1-100 grain, Sodte Sulphas 1-4 grain, 1.50 41 15 Atropia Sulphas 1-150 grain, Soda Sulphas 1-4 grain, 1.50 16 Strychnia Sulphas 1-60 grain, Soda Sulphas 1-4 grain, 1.50 “ 17 Strychnia Sulphas 1-100 grain, Soda Sulphas 1-4 grain, 1.50 “ 18 Strychnia Sulphas 1-150 grain, Soda Sulphas 1-4 grain, 1.50 “ 19 Apomorphia Mur. 1-10 grain, Soda Sulphas 1-8 grain, 3.00 Per case of io tubes or 200 tablets. No. 20 Apomorphia Mur 1-20 grain, Sodse Sulphas 1-8 grain, - $2.00 ‘‘ 21 Pilocarpin Mur. 1-4 grain, Sodse Sulphas 1-4 grain, 5.00 “ 22 Pilocarpin Mur. 1-8 grain, Sodse Sulphas 1-4 grain, 3.00 “ 23 Pilocarpin Mur. 1-20 grain, Sodse Sulphas 1-4 grain, 2.00 “ 24 Pilocarpin Mur. 1-2 grain, Sodse Sulphas 1-4 grain, 9.00 “ 25 Pilocarpin Mur. 1-3 grain, Sodse Sulphas 1-4 grain, 6.50 “ 26 Pilocarpin Mur. 1-10 grain, Sodse Sulphas 1-4 grain, 2.50 “ 27 Aconitia 1-60 grain, Sodse Sulphas 1-4 grain, 3.00 “ 28 Aconitia 1-130 grain, Sodse Sulphas 1-4 grain, 2.00 “ 29 Aconitia 1-260 grain, Sodse Sulphas 1-4 grain, 1.50 “ 30 Morph. Bi-Meconas 1-3 grain, Sodse Sulphas 1-4 grain, 3.00 “ 31 Morph. Bi-Meconas.1-4 grain, Sodse Sulphas 1-4 grain, 2-50 “ 32 Morph. Bi-Meconas 1-6 grain, Sodse Sulphas 1-4 grain, 2.00 “ 33 Morph. Bi-Meconas 1-8 grain. Sodse Sulphas 1-4 grain, 2.00 “ 34 Hydrarg, Chlor. Corros. l-30gr., Sodse Sulphas 1-4 grain. 1.50 “ 35 Hydrarg. Chlor. Corros. 1-60 gr., Sodse Sulphas 1-4 grain, 1.50 “ 36 Digitalin 1-100 grain, Sodse Sulphas 1-4 grain, 1.50 “ 37 Atropise Sulphas 1-200 grain, Sodse Sulphas 1-4 grain, 1.50 “ 38 Cocaine Hydrochlor. 1-6 gr., Sodse Sulphas 1-4 grain, 3.50 “ 39 Cocaine Hydrochlor 1-8 gr., Sodse Sulphas 1-4 grain, 3.00 “ 40 Cocaine Hydrochlor. 1-10 gr., Sodse Sulphas 1-4 grain, 2.50 They are put up in Cylindrical Tubes, convenient for carrying in Hypodermic or Pocket Case, ten Tubes in a box, with twenty tablets in each Tube. Note.—It will only be necessary in ordering, to specify the Numbers as above. These Tablets will be sent by mail, on receipt of the proper amount. JOHN WYETH & BROTHER. CHEMISTS. PHILADELPHIA. THE Model Vaccine Propagating Establishment the United States. BOVINE VIRUS. \\ 7E take pleasure in advising Physicians and Druggists, that we have recently organized on a very extensive scale, a vaccine propagating estab- lishment in Chester County, and are now prepared to furnish bovine virus of the highest quality, from Lymph obtained for us by Dr. Chas. E. Sajous, of this city, from the Belgian Government Bureau of Vaccination, and School of Veterinary Medicine, having assured ourselves after an extended inauiry, that the best virus was cultitvated in Belgium. An exhaustive pamphlet on Bovine Virus, its production and preservation, with a comparison of the respective merits of Bovine and Humanized Lymph, containing, also, a description of our Vaccine Farm, will be sent by mail to those who desire it. We particularly recommend the use of ivory points in preference to Quill Slips, as, experience has i*oven the results from the former to be much more satis- factory. We are prepared, however, to supply the latter when desired. Our points will remain active for three -weeks, if kept in a cool dry place, after which time we will not guarantee them. We will replace with other virus, all vaccine points which fail in primary vaccinations, when used within the time mentioned above, but not, if used after that lapse of time. PRICE-LIST. Ten Ivory Points, (in vial), - - $1.00 Single Points, each, - - - - .20 Vaccinators, each, - .60 A liberal discount to dealers. The above will be sent by mail on receipt of the proper amount. JOHN WYETH & BROTHER, PHILADELPHIA.