GEO. B. DOWLING, M, D., 
President. 
H. P. NICHOLS, 
Sect'y & Treas. 
The 
MEDICAL 
Qxygen Qompound Qo^, 
498 THIRD AVENUE, 
New York. 
Telephone, 243-38th, igtj-eetl ALFRED D. BEEKEN, 
13 PARK ROW, 
NEW YORK. In introducing to the Profession this new 
preparation, a compound of Oxygen and Nitro- 
gen we do not claim to have discovered any 
new virtues in a therapeutic agent which has been 
for some years on trial and which has demon- 
strated, to all who have made use of it, its great 
efficiency in conditions calling for its administra- 
tion. 
It has seemed to us, in view of the fact that the 
market has been over supplied with preparations 
of this gas, many of which were unstable com- 
pounds, liable to deteriorate between the time of 
production and the moment of use, and many too 
being of variable strength, and not infrequently 
containing very different propoitions of Oxygen 
and atmospheric air, retailed at extravagant prices, 
that there was open to us a field for the introduc- 
tion of an Oxygen compound which should be 
always the same strength, always free from adul- terations and dilution, and always containing 
exactly the proportions of Oxygen and Nitrogen 
which have been found by skillful practitioners to 
be the very best for the accomplishment of the 
desired ends. 
The therapeutic value of Oxygen, in the form 
supplied from the great laboratory of Nature* 
namely, fresh air, is well understood. Why do we 
send our invalids, convalescents and persons of 
delicate health to the plains of Texas, the heights 
of the Rocky Mountains, the wooded hills of the 
Adirondacks? Is it not that in these localities 
they may breathe an atmosphere free from impur- 
ity, and abounding in that life-giving and disease- 
destroying agent Oxygen ? Following on the line 
of thought suggested by this practice, a practice 
as old as the history of medicine itself, the idea is 
naturally conceived that Oxygen in some form 
will be of the greatest benefit if it can be supplied 
in a shape suitable to its administration at the 
bedside and in the physician’s office to those 
whose strength, business occupation or means do 
not permit them to journey to the lands where this 
vitalizing agent may be found in greatest quan- 
tities. 
Oxygen in its pure state is too powerful a sub- 
stance to be used to any extent in medicine. To 
accomplish its best results it must be diluted with some other substance. This being the case, what 
is to be preferred to Nitrogen, a substance selected 
by Nature herself as a medium for the dilution of 
a gas too powerful to be allowed to come in con- 
tact in its pure state with organic matter. No 
secret is made of the formula of this well recog- 
nized curative agent. After careful experiment it 
has been found that Oxygen, combined with Nitro- 
gen monoxide in the proportions of two atoms of 
the former with one of the latter, produces a com- 
pound in part a mechanical mixture, and in part a 
true chemical union of its component parts, which 
has been found to possess singularly remarkable 
powers in controlling many disease processes 
affecting many different organs of the body. As 
referred to in the opening sentences of this brief 
statement there is ground for belief that many 
preparations now on sale are largely diluted, and 
not at all what their makers claim them to be. In 
order to supply a remedy constant in its composi- 
tion, and which may therefore be expected to be 
constant in its operation, the manufacturers of this 
preparation have spared no time and patient 
investigation, and believe that with their improved 
methods of manufacture, and careful supervision 
by competent chemists, they have succeeded in 
placing upon the market a compound of Oxygen 
and Nitrogen which will meet the wants of the practising physician and which will be absolutely 
reliable, leaving no margin of doubt for the possi- 
bility of a failure in its therapeutic action due to 
careless methods of manufacture. 
Owing to these same improved methods of pro- 
duction, reference to the price lists annexed will 
show that this company is prepared to supply this 
superior article at a price less extravagant and 
more within the reach of all, rich and poor alike. THERAPEUTIC ACTION OF OXYGEN. 
With a proper realization of the important share 
Oxygen has in the organism of animals and 
plants, it seems incredible that physicians and 
surgeons have until recently failed to perceive the 
immense possibilities in its use as a therapeutic 
agent in many forms of disease. 
The necessity of a constant supply of Oxygen 
for purposes of respiration is well understood, and 
this fact has been dwelt upon and impressed upon 
all, by those who have made a study of the laws of 
hygiene. 
This is well as far as it goes, but it remains for a 
few earnest workers to materialize and proclaim its 
advantages in the treatment of disease. It is 
needless to recapitulate the function of Oxygen in 
the various chemical processes going on in the 
human economy. These are well understood by 
all, and it is equally well understood that a diminu- 
tion in the proper supply of Oxygen to the organ- 
ism, produces results far reaching and destructive, 
and that its total deprivation insures speedy death 
to animal life. This being the case, it is irrational 
to suppose that certain conditions characterized by 
mal-nutrition, lack of proper assimilation and gen- 
eral lack of vitality and health, will be not greatly benefited by the exhibition of this agent in a form 
suitable for ready introduction into the system. 
This fact seems to be so well established that 
argument is unnecessary to convince all of its truth. 
It is true objections may be raised against the 
inhalation of Oxygen. Why, it is said, give Oxy- 
gen artificially prepared when we find it, especially 
in the country under normal conditions, and in a 
mixture appropriate to our needs ? Truly it would 
be desirable if we could put all our invalids and 
convalescents under such happy surroundings. 
This, however, cannot be done, and admitting it 
we do not know but that, if the thorough oxygen- 
ation of the blood gives such therapeutic results, 
an artificially increased arterialization wouldnotput 
us in condition to more easily resist certain disease- 
producing influences. Again it may be said that 
breathing air too highly oxygenated may be harm- 
ful to the system. This is true, and it is for this 
reason that in the preparation of this Oxygen com- 
pound such care has been taken to present it in a 
form incapable of doing injury to the most sensi- 
tive animal structure. 
Another property of Oxygen is its well known 
antiseptic power ; disease germs cease to be active 
in an atmosphere composed entirely of Oxygen, 
and an abundance of this agent tends to delay and 
destroy their growth and reproduction. Hence the value of Oxygen in diseases of the lungs, which 
are now known to be produced by the multiplica- 
tion of disease germs in these organs. In addition 
to this sphere of action, an inhalation of the 
Oxygen compound under moderate pressure tends 
to open up air cells which have become closed, 
owing to relaxation and partial adhesion of their 
walls. This combined with certain gymnastic exer- 
cises calculated to expand the chest, is of the 
greatest service in warding off incipient phthisis. 
Enough has been said to indicate the general 
benefit to be derived from the administration of 
the Oxygen compound in the treatment of disease. 
A brief statement of some of the special con- 
ditions in which it is indicated, with a few of the 
beneficial results will be in order. 
Bronchial Disorders. 
In cases of acute bronchitis, particularly of the 
capillary variety, this remedy will be found of 
service. Especially is this the case in old persons 
with weak-acting hearts, where owing to insuffi- 
cient oxygenation of the blood, cyanosis and 
dyspnoea are prominent features. In these cases 
it acts like magic, a few inhalations give a sense 
of relief, which by repetition can be renewed, and 
which will do much to tide the patient over the critical stage of the disease. The relief is great, 
and often distressing orthopnoea is entirely re- 
lieved, and comfort and quiet rest secured. This 
alone would be sufficient excuse for retaining the 
Oxygen compound in the list of remedial agents. 
Emphysema of the Lungs. 
This disease in its pronounced form is often 
characterized by attacks of bronchial asthma. 
The lungs become distended during the attacks, 
but owing to the lack of elasticity in the walls of 
the air vesicles, air cannot be expelled, and as 
new air cannot be taken in, that which is already 
there soon loses its oxygen, and becomes unfit for 
respiration. This accounts for the great oppres- 
sion and cyanosis characteristic of these attacks. 
Mechanically, the lungs are prevented from prop- 
erly supplying the blood with oxygen. Here it is 
that the inhalation of the oxygen compound by 
supplying a quantity of oxygen greater than that 
normally existing in the air vesicles, acts like 
magic in relieving the distressing symptoms and is 
a remedy unexcelled. 
Heart Disease, Organic Lesions. 
A great field for the administration of oxygen, 
and one .in which it has won many laurels, is the condition of pulmonary engorgement and oedema 
so common in the later stages of valvular disease 
of the heart, that organ by its gradual giving out, 
allowing the venous system to become overloaded, 
with consequent stasis and congestion of the 
pulmonary circulation resulting in accumulation 
of serum in the air vesicles themselves. This of 
course, interferes by its very presence with the 
entrance of a proper supply of air into the air- 
vesicles and by infiltration of thin walls destroys 
their elasticity thus preventing the expulsion of 
air which has already been deprived of its oxygen 
and become overloaded with carbonic acid. In 
these cases the oxygen gas will do wonders, sup- 
plying as it does, at the very point where it is 
most needed, oxygen in a state to be easily and 
quickly taken up by the blood and carried as a 
vitalizing agent to every part of the debilitated 
organism. A single case will illustrate this. 
Mrs. S—, aged 55. Mitral insufficiency of long 
standing. From over exertion and anxiety seized 
with palpitation and irregular action of the heart. 
Examination showed that the heart was greatly 
dilated, and that its action was very feeble. 
Temperature sub-normal, strength diminished, 
extremities cold, cyanosis very marked. Inhala- 
tions of oxygen were ordered every two hours in 
addition to the proper remedies. Each inhalation gave relief, respiration became easier, heart action 
stronger and cyanosis disappeared. In a few days 
the acute dilatation of the heart subsided and 
patient shortly after returned to her normal con- 
dition, or that which had been normal for several 
years previous. 
This is only one of a number of such cases in 
the writer's experience. 
Fatty Degeneration of the Heart. 
In this condition, essentially a giving out pro- 
cess, we find the same conditions of the respiratory 
organs that occur in cases of valvular lesions of 
the heart. The lungs are overloaded with blood, 
the amount of air in them is necessarily dimin- 
ished, and the normal interchange of oxygen and 
carbonic acid is to a great extent interfered with. 
Here again the administration of the Oxygen com- 
pound is indicated and if used in time will work 
wonders. 
Pulmonary Phthisis. 
Pathologists recognize a form of chronic de- 
struction of lung tissue, not characterized by the 
presence in the diseased tissue of the tubercle 
bacilli. It is in this variety of pulmonary disease 
that the Oxygen compound has won its greatest 
laurels. It aids in delaying and often stops the necrotic process going on. It supplies oxygen to 
the blood, which, owing to the diseased condition 
of many air vesicles, is receiving a supply of that 
substance far less than necessary for the healthful 
state of the system. By its inhalation under press- 
ure it aids in expanding and opening up air vesi- 
cles which are not yet diseased, but which have 
collapsed and whose walls are adherent, thus ren- 
dering them fit localities for the starting of fresh 
points of lung necrosis. 
With the above facts well known and proved, 
what conscientious physician will fail to try, in 
cases calling for its administration, this agent so 
potent for good ? The time is past for deriding it, 
and placing it in the same category with much- 
advertised nostrums. It is not a “ cure all,” but it 
has certain well-defined and well-understood fields 
of action and in these conditions it is supreme. 
In justice to patients, every physician should in- 
vestigate and make a trial of this powerful agency. 
Having once seen its effects, it is easy to prophecy 
that its administration will constantly become 
more and more frequent, with consequent increas- 
ing benefit to patients suffering from disease which 
come within its legitimate sphere of action. 
We are prepared to furnish Oxygen Compound 
Gas in cylinders containing one hundred and fifty 
gallons, together with all the apparatus for admin- istration, at the nominal price of $10.00. The 
apparatus we loan (never sell) fora period of sixty- 
days free of charge ; if retained longer a charge of 
one dollar per month will be made. 
We do a medical business ; after which state- 
ment it need scarcely be added that all orders are 
filled immediately. Out of town orders will be 
shipped by express the same day and as soon as 
received 
Address or send to 
Medical Oxjjp Compound Co. 
498 Third Avenue, 
BY TELEPHONE l NEW YORK CITY. 
No. 343—88th Street. 
Our Gas can be obtained 
DAY and NIGHT from 
She Wilson E?hai^magy, 
Southwest cor. 34th St. and. Broadway 
4.1TD 
(ZaSwell, Massey G©. 
Cor. 25th Street. 1121 BROADWAY. AGENCIES. 
FOR THE BENEFIT OF OUR PATRONS at a distance, 
WE HAVE PLACED OUR GAS WITH THE FOLLOWING PROMINENT 
DRUGGISTS:— 
BOSTON, MASS. 
Theodore Metcalf & Co., Otis Clapp & Son, 
Copley Square and 39 Tremont St. Park Square. 
SPRINGFIELD, MASS. 
H. & J. Brewer, 463 Main Street. 
PROVIDENCE, R. I. 
Otis Clapp & Son, Leith & Danforth, 
307 Westminster Street. 163 Westminster Street. 
NEWPORT, R. I. 
Hazard, Hazard & Co. 
NEW HAVEN, CONN. 
E. A. Gessner, Apothecaries Hall. 
HARTFORD, CONN. 
Philo W. Newton, Chas. A. Rapelye, 
Allyn House Drug Store. 325 Main Street. 
BRIDGEPORT, CONN. 
F. S. Stevens & Co., 315 Main Street. 
CINCINNATI, OHIO. 
Max Wocher & Son, 105 West Sixth Street. 
NEWARK, N. J. 
Lewis Bros., 238 & 240 Market Street. GAS HOLDERS # PRESSURE GUAGES. 
Rubber Gas Bags covered with silk of three gallons 
capacity, for the convenience of physicians wishing to trans 
fer gas from their office to the house of their patient will be 
furnished for three dollars each. 
Pressure Guages for testing amount of gas in the cylin- 
der can be had on application for three dollars each. 
MEDICAL OXYGEN COMPOUND CO. 
498 Third Ave., New York.  238 88th? 
OXYGEN COMPOUND G0.,«€ 
498 THIRD AVENUE, 
NEAR 34th STREET. 
A. CARD. 
New York, October 15, 1891. 
We would call your attention to the fact that we are now enabled to furnish Oxygen 
Compound Gas of superior quality for the nominal price of $10 for one hundred and fifty gallons. 
This gas is manufactured with great care under the most experienced supervision and is exactly what 
we represent it to be, viz. two parts oxygen and one part nitrogen mon-oxide, there being absolutely 
no dilution by atmospheric air. 
This fact is of the utmost importance to physicians, as they are certain of the agent pre- 
scribed and can then note the effect in different cases. 
We would direct your attention to the following conditions in which this gas is highly 
recommended and where its efficiency is well known : 
Asphixiation by coal gas, sewer gas, illuminating gas and by drowning. 
In these cases the oxygen acts as nothing else can, its effect is immediate and the patient is 
instantly revived. 
In Phthisis Dvspnoea from all causes. Pneumonia, Heart Failure, CEdema of the lungs, and 
Anaemia the gas will furnish all the life giving properties of pure air without any exertion in breathing 
on the part of the patient. The treatment allows the patient to recuperate by the additional strength 
acquired in easy respirations. 
Our gas is put up in a convenient shape for handling, in cylinders containing one hundred and 
fifty gallons, and is ready for immediate use, being supplied with tubing, inhaler bottle, and mouth- 
piece. This apparatus we loan fora period of two mouths without charge, but as an especial favor, we 
ask that cylinders be returned as soon as empty. 
We can furnish this gas in all emergency cases at the shortest possible notice, being connected 
by telephone, No. 243 38th. All orders in the city we will fill immediately, and those out of town 
will be shipped by express the same day as when received. 
For detailed particulars with cases cited and treatment discussed by the physicians in charge, 
send for pamphlet. Soliciting your patronage, we remain, yours truly, 
MEDICAL OXYGEN COMPOUND CO. 
N. B.—See that all cylinders are painted brown and have our name plate and address.