\mJiAtsT y*~ (u*s^u^^dk ^X ffc- c^zJLrt. ,. 83 THE INVENTION ANAESTHETIC INHALATION; "DISCOVERY OF ANESTHESIA." BY WILLIAM J. MOETON, M. D., membbh of the new york academy op medicine -, op the new york academy op sciences; op the new yobk medico-legal society; op the new york county medical society; of the American neubological association; assist- ant to the chair op diseases op the mind and nervous system, in the medical department op the university op the city op NEW YORK; member and secretary OF THE NEW YORK NEUROLOGICAL SOCIETY, ETC., ETC. » [REPRINT, WITH ADDITIONS AND ALTERATIONS, FROM " THE VIRGINIA MEDICAL MONTHLY:' MARCH, 1880.] NEW YORK: D. APPLETON AND COMPANY, 1, 3, and 6 BOND STREET. 1880. THE INVENTION OF ANAESTHETIC INHALATION; OK, "DISCOVERY OF ANESTHESIA." BY WILLIAM J. MORTON, M. D., MEMBER OT THE NEW YORK ACADEMY OF MEDICINE ; OF THE NEW YORK ACADEMY OF SCIENCES; OF THE NEW YORK MEDICO-LEGAL eOCIETY; OF THE NEW YORK COUNTY MEDICAL SOCIETY; OF THE AMERICAN NEUROLOGICAL ASSOCIATION; ASSIST- ANT TO THE CHAIR OP DISEASES OF THE MIND AND NERVOUS SYSTEM, IN THE MEDICAL DEPARTMENT OP THE UNIVERSITY OF THE CITY OF NEW YORK; MEMBER AND SECRETARY OP THE NEW YORK NEUROLOGICAL SOCIETY, ETC., ETC. [REPRINT, WITH ADDITIONS AND ALTERATIONS, FROM " THE VIRGINIA MEDICAL MONTHLT,n MARCH, 1880.] NEW YORK: D. APPLETON AND COMPANY, 1, 3, and 6 BOND STREET. 1880. WlOA THE INVENTION OF ANAESTHETIC INHALATION, OR "DISCOVERY OF ANAESTHESIA." " The invention all admired, and each how he To be the inventor missed, so easy it seemed, Once found, which yet unfound most would have thought Impossible." Milton. That a new " discoverer of Anaesthesia " has been discov- ered, at this late date even; that extraordinary and novel claims for him have been recently brought before the medical and general public with energy and persistency by a special advocate ;*that, in short, the Ether controversy, long since con- sidered as a res adjudicata. has been again reopened, forms in itself a sufficient apology for presenting a fresh review of the subject in a manner which shall include the claims made for this third and latest after-claimant. And whether this * Dr. J. Marion Sims, "Virginia Medical Monthly," May, 18V7, and subsequent editions of reprints. A third position assumed by the same writer, who, in 1861» following the lead of Parker, Mott, Francis, and hundreds of others of the best- known physicians of this city, appended his name to the memorial stating that " for this discovery, the first great triumph of placing in the hands of the profes- sion an agent capable of rendering the patient safely and at will utterly insensible to the stroke of the surgeon's knife, the world is indebted to Dr. W. T. G. Morton, of Boston " ; who again, in 1873, said in a public address, " To my mind it is as clear that Wells was the discoverer of Anaesthesia as it is that Columbus was the discoverer of America " ; and who now, in 1877, thinks " that Long was the first man to intentionally produce Anaesthesia for surgical operations," and was therefore " the true discoverer of Anaesthesia." 4 modern revival of a claim never viable will be found to be based upon an accession of new and reasonably valid proofs and facts, or whether it is a needless resurrection of long- buried antiquarian remains, unwarranted by any new fact de- veloped, and interesting merely in an incidental and histori- cal way, is a point which will best appear upon making a plain presentation of the case. Before 18^6, in all time, surgery was agony. The universal practice of Anaesthesia, as it is understood to-day, began in 1846. Before this date pain was inevitable. Mankind in hospitals, in homes, on all occasions of pain inci- dent to surgery and medicine, suffered without relief. After this date pain was avoidable. Mankind was offered and accept- ed immunity, and every physician and surgeon in the world held in his hand the means and the method of annihilating it. Thus voluntary escape from pain forms an epoch in the world's history, as definite as the beginning of the Christian era, of vaccination, or of telegraphy; an epoch marked, more- over, by results to humanity more important and more endur- ing than those gained by any single contribution ever made to medicine.* The practice of surgery underwent at this date a striking revolution, brought about by the revelation of the fact that sulphuric ether, properly managed, would produce complete insensibility to the pain of surgical operations. This revelation to the world was made by Dr. W. T. G. Morton, of Boston ; f he was the issuer of the new facts. At * "If America had contributed nothing more to the stock of human happiness than Anaesthesia, the world would owe her an everlasting debt of gratitude." —Professor S. D. Gross, Address delivered April, 1879. " It is probable that the American inventor of the first anaesthetic has done more for the real happiness of mankind than all the moral philosophers from Soc- rates to Mill."—Lecky, " History of European Morals," vol. i., p. 88. f At the time of the invention of anaesthetic inhalation Dr. Morton was a young man of twenty-six years, industriously making his own way through the world. Early thrown upon his own resources by an unfortunate business venture of his father's, but with a good New England academy education, moderate ambition, courage, and a clear conscience to back him, he had started out, and had met with those obstacles which usually attend the career of the self-made man—obstacles which, while they delay success, at the same time develop character. His final goal was the attainment of a medical degree and the practice of medicine. With this in 5 hand stood a Bigelow, with the incisive insight to welcome and counsel, and the will and the ability to sweep aside the prejudice and doubt of the hospital surgeons, and within the historic walls of the Massachusetts General Hospital were found a Warren and a Hayward to verify the revelation with judicial fairness, and to place upon it verified the stamp of their scientific and professional approval; and a Holmes sug- gested the terms Anaesthesia and Anaesthetics.* Thus issued, fostered, verified, and christened, the revela- tion went forth into the world in 1846, perfect at its outset. view, he had already, in 1844, entered his name as a student in the office of a physician in Boston, and had shortly afterward matriculated in the Harvard Medical School, where he faithfully attended the courses of lectures. While still a student of medicine, practicing the allied branch of dentistry by the way as a means of support, his attention became fixed upon the anaesthetic properties of sulphuric ether. Soon came his announcement of success in its use, and the all-absorbing controversy which ensued of course precluded further medical studies. Afterward the honorary degree of M. D. was conferred upon him by the Washington University, of Baltimore, Md. That Dr. Morton was " ignorant of medicine and without a degree " has been so often repeated by the tireless and bitterly personal detractors of the early days of the controversy, and thought- lessly reiterated since, justifies this brief allusion to a branch of the subject slightly apart from the points at issue. * Professors Henry J. Bigelow, George Hayward, John C. Warren, and 0. W. Holmes, of the Harvard Medical School. Only lately a distinguished American writer states that the word Anaesthesia " was coined and introduced into our med- ical nomenclature in 1847, by the late Sir James Y. Simpson." The following characteristic letter establishes the fact that the word originated in America. Dr. Morton at first used the term Letheon, suggested by the fabled river Lethe, to denote oblivion both to pain and to consciousness, but quickly adopted the new word. " Boston, November 21, I846. " My dear Sir : Everybody wants to have a hand in a great discovery. All I will do is to give you a hint or two as to names or the name to be applied to the state produced and the agent. " The state should, I think, be called ' Anaesthesia '; this signifies insensibility, more particularly (as used by Linnaeus and Cullen) to objects of touch. The ad- jective will be ' anaesthetic' Thus we might say, the state of anaesthesia or the anaesthetic state. The means employed would be properly called the anti- aesthetic agent. Perhaps it might be allowable to say anaesthetic agent, but this admits of question. ... I would have a name pretty soon, and consult some accomplished scholar, such as President Everett or Dr. Bigelow, senior, before fixing upon the terms which will be repeated by the lonpues of every civilized race of mankind. You could mention these words which I suggest for their con- sideration; but there may be others more appropriate and more agreeable. Yours respectfully, 0. W. Holmes. " Dr. Morton." 6 The news quickly reached Europe. So sudden was this conquest of pain that, as is well said by Sir James Paget,* in referring to the event, " it might almost be said that in every place, at least in Europe, where the discovery was promoted more quickly than in America, the month might be named before which all operative surgery was agonizing, and after which it was painless." Anaesthesia came into universal prac- tice ; ether remained alone in the field as an anaesthetic for more than a year, when Dr., afterward Sir James Y. Simp- son f suggested chloroform as a substitute for it. % A number of other substitutions have since been made, but have failed to supplant the original ether. And we may note, in passing, the gratifying fact that the practice of Anaesthesia is wholly of American origin. Proof that previous to 184-6 surgery was agony. But it may be asked, was this knowledge new to the world? "Was it in 1846 for the first time placed in the pos- session of mankind ? That it was, absolutely and without * " Escape from Pain: the History of a Discovery." By Sir James Paget, Bart. "The Nineteenth Century," December, 1879. f In sending to Dr. Morton his first publication upon chloroform, Dr. Simpson writes : " My dear Sir : I have much pleasure in offering for your kind acceptance the accompanying pamphlet. In the ' Monthly Journal of Medical Science' I have a long article on Etherization, vindicating your claims over those of Jackson. " Of course the great thought is that of producing insensibility, and for that the world is, I think, indebted to you. , " With very great esteem for you, allow me to subscribe myself, yours very faithfully, J. Y. Simpson. " Edinburgh, November 19, 1847." Afterward Dr. Simpson diffused this credit over a great number of observers and experimenters, leaving the main idea ascendant that the settled and fixed practice of Anaesthesia as known to-day did not begin until 1847. The files of all medical journals throughout all countries published between October, 1846, and November, 1847, are sufficient refutation of this view of the case. % This interval of a year is sometimes strangely forgotten, as witness the fol- lowing recent remark: " The men who taught us had seen the introduction of chloroform rendering possible prolonged operations, and an accuracy of surgical dissection which was before unattainable."—" Advances in Surgery during the Past Twenty Years." By Roderick Maclaren, M. D., etc. " Lancet," January 31, 1880. If we say, rather, that they had seen all this by ether for a year before chloroform was mentioned as an anaesthetic, we shall utter the fact. 7 reservation, is established by the common consent of all emi- nent authorities, tracing them up to the very day even of Dr. Morton's first demonstration. In 1839 the distinguished surgeon Yelpeau wrote: " To avoid pain in surgical operations is a chimera which it is not allowable to pursue at the present day. The cutting instru- ment and pain are two words which never present themselves singly to the mind of the patient, and of which we must ne- cessarily admit the association." And Orfila, in his " Toxicol- ogy," declares " absolute insensibility to pain under surgical operations by etherization to be a discovery entirely new." Professor J. C. Warren, already referred to, says: " The discovery of a mode of preventing pain in surgical operations has been an object of strong desire among surgeons from an early period. I have freely declared, that, notwithstanding the very large doses of narcotic substances, this desideratum had never been satisfactorily obtained." And again, January 6, 1847: " I hereby declare and certify that I never heard of the use of sulphuric ether by inhalation as a means of pre- venting the pain of surgical operations, until it was suggested by Dr. William T. G. Morton in the latter part of October, 1846." Sir Benjamin Brodie, in an address delivered at St. George's Hospital, London, in October, 1846, said: "There is no greater desideratum either in medicine or surgery than to have the means of allaying or preventing bodily pain, not only in surgical operations, but in other cases also; but there is good reason to apprehend that it has not been reserved for the revival of animal magnetism under a new name to accom- plish that for which all physicians and surgeons have been looking in vain from the days of Hippocrates down to the present time." What Brodie despaired of became an accom- plished fact within twenty-four hours of the delivery of his. address. The facts thus far detailed are fixed and immutable. Not a word admits of discussion or denial; they demonstrate clearly that something novel was revealed to the world in 1846—something not yet in the possession of mankind; in themselves they are prima facie evidence that what was new 8 was a discovery—the discovery of Anaesthesia as applied to surgery—and that this discovery was made in 1846. The discovery was made in 184-6 • it went forth from Dr. Morton's hands. He alone vms known or heard of in connection with it until after its success was established. And but one man was known as author in relation to these events, and that man was Dr. Morton. He it was who asked for an opportunity to administer the ether, and his hand ad- ministered it before a crowded amphitheatre of skeptical wit- nesses; his, the responsibility of failure and its attendant ridicule, and his, the risk of an almost certain indictment for manslaughter, in case of the death of any one of the patients upon whom the preliminary experiments were made which led to this public trial. During this trying and crucial period he alone was known or heard of as originator in connection with the use of ether until after its safety, efficacy, and utility had been established beyond a doubt. Claimant he was not, for from whom could he claim anything? No one else had claimed to have discovered Anaesthesia. It did not exist—or the testimony of Orfila, of Brodie, of Warren, and of all con- temporaneous and eminent authorities is false. It was not therefore claimable from any one. It originated then and there, in 1846. At that moment it was revealed, announced, verified, introduced, and popularized, and the discovery went forth to the world—issued by Morton, indorsed by the Hospital. Antiquarian exploration, prompted, whether it be by sophistical or by honest partisanship, assails this position in vain, and on this basis posterity will render that verdict unani- mous which promoters of confusion now seek to delay. From this elevated plane Dr. Morton, living, combated assaults with a forbearance not accorded to him in return, but with a per- sistency which was convincing of his faith in the justice of his cause; and in his grave he awaits the world's unanimous ver- dict of confirmation and approval. After-claimants arise ; their characteristics. But at this point in the history of Anaesthesia, clear-cut, defined, and impregnable as Dr. Morton's position would seem 9 to be, we are brought straightway to the unfortunate period of controversy, the inevitable sequel of every great discovery and invention. Numerous after-claimants arose and bid fair yet to arise. The after-claimant, whether with good intentions or with bad, seems to be the natural parasite of the discoverer or in- ventor. If honest, he claims that certain prior efforts of his own were of a nature sufficiently definite to constitute the dis- covery or invention. And such a claim may possess a certain amount of merit if these efforts have been put on record at the time, with proper dates and witnesses, it may be; if this has not been done, their value can not be relied upon, for every one knows how easy a thing is to repeat after it has been once accomplished. The puzzle solved, its solution seems ridicu- lously simple, and each wonders how he failed to do it. But it is obviously unjust, with another's solution in hand, to inter- pret previous steps and attempts as equivalent. The little misstep on this side or that is set straight, and such an after- claimant comes conscientiously to believe, since he was so near being, that therefore he was, at this prior time, the dis- coverer. He forgets that, while he paused onthe verge, an- other by chance or intent pushed on, by the same route per- haps, and took the final step of success. But the after-claim- ant ignores this final step. He substitutes his imperfect results previously obtained for the now perfect ones ; exchanges his own uncertainties for the new certainties; and is now said to " antedate " the unfortunate discoverer. The injustice of this is so glaring that the scientific world has been driven to admit the law that an observer can not claim credit for his observa- tions unless they have been submitted to some proper scientific tribunal, and thus at least, if not in print, become published. The reasons for and the elements of every discovery soon to come, for instance, are uow working in many human minds. When the prospective discovery is born, each worker may be- lieve that the discovery is his. But the world must honor some one of them, and it has always selected him whose work was coincident with the public birth of the discovery, who both detected the main fact or principle involved and demon- strated its application, and who also issued, announced, and proclaimed it, especially if he did this against difficulties and 10 prejudices. And such issuer's position is many times stronger if he has had absolutely no relation personally, or in writing or print, with the after-claimant, and if, in addition, the latter has not a scrap of published record to show for his alleged prior discovery. But there is another kind of after-claimant whom words can not too strongly denounce. With nothing to lose, since he has done nothing, and everything to gain, he makes up in au- dacity what he lacks in facts. He advances his claims " with a presumption exactly proportioned to his inability to estab- lish them." He thrives in the confusion he creates, and takes advantage of mankind's intuitive love of fair play to inspire a doubt which the world, occupied or perhaps indifferent, may not at once dispel. The inventor and revealer of the Anaes- thesia of 1846 was to have an experience of both these classes. Definition of terms, "discovery of ancesthesia." But we must pause a moment at this point to ask what is meant by the " discovery of Anaesthesia." The terms in them- selves have been responsible for much confusion. Do they comprise the conception—the theory, an attempt to carry out the theory in practice, or the perfected and now familiar re- sult ? The word Anaesthesia (from a, non, and a'lcrdr)