MEDLARS INDEXING INTEGRATED AUTHORITY FILE Chemical Section 1968 NATIONAL LIBRARY OF MEDICINE BIBLIOGRAPHIC SERVICES DIVISION INDEX SECTION z MII3 ?j Si ATES GOVERNMENT DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE PUBLIC HEALTH SERVICE Memxyramxkim TO Indexers, Intra- and Extramural date: December 1968 from Head, Index Section subject: Integrated Authority File, Chemical Section Enclosed is the first installment of the Chemical Section of the IAF. A typical entry carries the Chemical Abstracts Service (CA) registry number; synonyms; chemical formulae, if available; other descriptive material and indexing instructions. Capitalized entries indicate propietary names. Entries all in capitals are MeSH terms. CA registry numbers are supplied for verification with the Desktop Analysis Tool. (DATS). All available synonyms are provided. They may include chemical riuiaes, proprietary names, trivial names, etc. If available, structural and molecular formulae are provided. Indexing instructions include IM as well as NIM terms. Further installments will be distributed when ready. N. HELP ELIMINATE WASTE J1T3TV7 kSTE COST REDUCTION PROGRAM*"^ A abdo;vrilon Syn. appendilon Contains: Herba absynthii, Radix angelica, Rhizoma calami, Fructus carvi, Flores chamomillae, Crocus sativus, Cortex frangulae, Rad. gentianae, Folia melissae, Fol. menthae pip., Rhizoma rhei. Index PLANTS, MEDICINAL (68) abequose Reg. 644484 A methyl-desoxyaldopentose (C^H^^) from Salmonella abortus equi. Index. PENTOSES (68) abminthic see DITHIAZANINE accelerin see factor VI ACD see acid citrate dextrose Acderm lotion Reg. A lotion used in the treatment of acne vulgaris, containing propylene glycol, phenazone, triethanolamine, sulphestol solution, and precipitated sulfur. Index SULFUR (IM) (68) AMINO ALCOHOLS (IM) (68) acedicon see dihydrocodeinone-enol acetate AB03 l l see N ,N -anhydrobis(£-hydroxyethyl) biguanide abrodil see METHIODAL abscisic acid Reg. Syn. abscisin II; dormin. An abscission-accelerating substance isolated from higher plants. Index PLANT GROWTH REGULATORS (68) acenocoumarin see ACENOCOUMAROL ACENOCOUMAROL (D7) (68) Reg. 152727 Syn. acenocoumarin; 3-(c*-acetonyl« 4-nitrobenzyl)-4-hydroxycoumarin; 3-(2-acetyl-l-p-nitrophenylethyl)- 4-hydroxycoumarin; acinocouraarin; nicoumalone; sinthrom; sintrom; syncumar. CO-V-cy*** OH abscisin II see abscisic acid Abstem Reg. Used as an adjunctive therapy in alcoholism. Contains citrated calcium carbimide. ' Index CITRATES (IM) (68) . CYANIDES (IM) (68) CHtCCK. 0 abstinyl see DISULFIRAM aceperone see N-((l-(3-£p-fluorobenzoyl)propyl) 4-piperidyl)methyl)-acetamide *ACEPROMAZINE (D6) (68) Reg. 61007 Syn. CB-1522; acetopromazine; 3-acetyl-10-(3-dimethylaminopropyl)- phenothiazine; notensil; plegicil. A tranquilizing agent. ss AC3 see 2-acetylamino-5-chlorobenz- oxazole CCC1H5 CH^CK^CH^W^K^ 2 u^-t.'.' .. '."'O Syr.. OV 511 .. co-.v.bination of malic, benzoic and 6.ilicyi.ic esters in an aqueous sol- ution of propylene glycol. It is effective in the treatment of leg ulcer. Index 5ZNZ0ATES (IM) (68) MALAXES (IK) (68) SALICYLATES (IM) (68) cetabuton see N- C( 1-(3-(p-fluorobenzoyl)propyl) 4-piperidyl)methyl3 -acetamide 2-acetamido-4-(5-nitro-2-furyl)-thiazole Reg. 531828 Syn. furium Used in the treatment of vaginitis. Index THIAZOLES (68) 2-acetamido-5-nitrothiazole Reg. 140409 Syn. acinitrazole; aminitrozol; Entramin A. A thiazole with parasiticidal properties. Index THIAZOLES (IM)(68) ANTI-INFECTIVE AGENTS (IM)(68) «cetalphophajides Reg. Index PLASMALOGENS (68) p-acetamidophenol see ACETAMINOPHEN 5-acetamide-l,3,4-thiadiazole-2- sulfonamide see ACETAZOLAMIDE 5-acetamido-2,4,6-triiodo-n- methylisophthalamic acid see IOTHALAMIC ACID p-acetamidobenzaldehyde thiosemicarbazone see THIACETAZONE 1-(p-acetamidobenzylidene)-2- isonicotinoylhydrazine Reg. 1158414 Syn. INKA-17. An isoniazid derivative. Index ISONIAZID (68) C-K*-N:;cH-<£3-jvLcCrt: K* 2-acetair.idof luorene see N-2-fluorenylacetamide X-(4-ccetamido-l-naphthylsulfonyl)- dodecanamide 9 Reg. 3818722 Syn. 4-acetylaminonaphthalene-l- lauroylsulfonamide; PANS. A sulfonamide Index SULFONAMIDES (68) CO 5 ACETAMINOPHEN (D6) Reg. 103902 f Syn. p-acetamidophenol; p-acetamino- phenol; p-acetylaminophenol; N-acetyl- p. aminophenol; p-aminoacetophenol; APAP; Amadil; Apamide; hydroxyacetanilide; Lonarid; multin; NAPA; HAPAP; panadol; Paracetamol. An analgesic. LU2(Cc^H--acetoxy-20,20-bis-peroxy-pregnane- li-cne. Reg. A coronary vasodilator. Index VASODILATOR AGENTS (IM) (68) PREGNANES (IM) (68) C- °^ 2-acetoxy-4'-chloro-3,5-diiodobenz- anilide Syn. SYD-230 Index ANTHELMINTICS (IM) (68) ANILIDES (IM) (68) acetoxycycloheximide Reg. 1508629 Index PRYIDONES (IM) (68) CYCLOHEXANE (IM) (68) 7 ot -(acetoxyethane)-oxyflavone Reg. 119415 Syn. recordil Index VASODILATOR AGENTS (68) (IM) FLAVONES (IM)(6$) 17- c«^-c«i-^^c4 N-acetyl-2-fluorenamine see N-2-fluorenylacetamide 3-acetyl-5-(4-fluorobenzylidene)-4- hydroxy-2-oxo-2:5-dihydrothiophene Reg. Syn. ICI 47,776 A substituted thiophene which inhibits electon transport by ' isolated mitochondria and has a species specific capacity to inhibit production of antibodies. Index IMMUNOSUPPRESSIVE AGENTS (IK)(68) THIOPHENES (IM) (68) ANTIMETABOLITES (IM) (68) I N-acetyl-D-galactosamine Index HEXOSAMINES (68) N-acetylgjucosamine deacetylase Reg. An enzyme hydrolyzing N-acetyl- glucosamine to glucosamine and acetic acid. }Vndex AMIDOHYDROLASES (68) acetylglucosamine-4-galactosido- 1,5-4-acetylgalactosaminide-l,5 see gastro-N-trisaccharide' dihydroxy-5*-cholanoic acid allochrysin A sulfonated gold derivative of 1-mer cap to-2-propano1. Index DBiERCAPROL (Bl) (68) GOLD (Bl) (68) allocryptopine Reg. 4792114 Syn. homochelidonine Index ALKALOIDS (68) allocrysin see allochrysin Alloferine see diallylnortoxiferine 21 allokainic acid A stereoisomer of kainic acid. Index PYRROLIDINES (68) CH i5 C- -i-----r C.v\j.CoOH ^ l-allyl-6-amino-3-ethyluracil Reg. 642444 Syn. aminometradine; aminometramide; mictine; katapyrin. Index DIURETICS (IM) (68) URACIL (IM) (68) Cri,crt*c«2. allophanamide see carbamylurea allopregnandione Reg. 566654 Syn. 5*-pregnane-3,20-dione Index PREGNANES (68) O allopregnane-3/5,16o(.-diol-20-one An adrenal cortex hormone causing increased urinary sodium excretion (paradox of action of mineral corticoids).. Index ADRENAL CORTEX HORMONES (Bl)(68) PREGNANES (Bl) (68) c~0 HO OH p-allylanisole see estragole 5-allyl-5-cyclohexenyl-2-thiobarbituric acid Reg. 3546290 Syn. intranarcon; kemithal; thialbarbitone. Index BARBITURATES (68) n-allyl-n-desmethylmorphine see NALORPHINE 6-allyl-6,7-dihydro-5H-dibenz£c,e3 azepine Reg. 130836 Syn. Ro 2-3248; azapetine; Ilidar. Index SYMPATHOLYTICS (Bl) (68) AZEPINES (Bl) (68) ALL0PURIN0L (D9) (68) Reg. 315300 Syn. BW 56-158; 4-hydroxypyrazolo-, (3,4-d)pyrimidine; lH-pyrazolo [3, 4-d]-pyrimidin-4-ol; Zyloprim. A xanthine oxidase inhibitor, used in the suppression of gout. Allpyral Reg. KX8057667 An alum-precipitated-pyridine sting- ing insect extract, used in the hy- posensitization treatment of patients allergic to stinging insects. Index TISSUE EXTRACTS (Bl) (68) BISECTS (Bl) (68) Wci4aC<+s CH. Allyldromoran see LEVALLORPHAN A4-17<*.-allylestrene-17/S -ol see allylestrenol 22 allyiestrcnol Reg. 432600 Syn. A4-17c*-allylestrene-17/S-ol; gestanon. A progestogen or progesterone derivative. Index PROGESTATIONAL HORMONES (60) 5-allyl-5-ethylb'arbituric acid Syn. ethallymal Index BARBITURATES (68) ll-allyl-l,2,3,9,I0,10a-hexahydro-- 4H-10,4a-iminoethanophenanthrene •< see LEVALLORPHAN j-allyl-5-isobutyI-2-thiohydantoin ;^g. 830897 Syn. albutoin (Co-ord(R)) Index HYDANTOINS (67) H Hi l A---N-Crt^CH=C] ailylisopropylacetamide Index AMIDES (67) Uii3C ^-CH2CH=CH2 0 5-allyl-5-(3-hexyn-2-yl)-l-methyl- barbituric acid see METHOHEXITAL 5-allyl-5-(2-hydroxy-3-iodopropyl) barbituric acid Reg. 3258524 Syn. D]_ Index BARBITURATES (68) N-allyl-3-hydroxymorphinan see LEVALLORPHAN 5-allyl-5-(hydroxypropyl)-barbituric acid Syn. D1H; HH-184; axeen; Ipronal. A barbiturate without hypnotic properties which has been used to treat the side effects of PAS and streptomycin in tuberculosis therapy. Index BARBITURATES (66) or CH2-CHCH2CHCNH2 CH(CH3)2 allylisopropylacetylcarbamide Reg. 528927 Syn. (2-isopropyl-4-pentenoyl)- urea; sedormid. Index HYPNOTICS AND SEDATIVES (66) CH2=CHCH2 (H3C)2CH::CHC0NHC0NH2 5-tlllyl-5-isopropyl barbituric acid Reg. 77021 Syn. allional; aprobarbital.aiuratl Index BARBITURATES (68) ' 5-allyl-5-isobutyl-2-thiobarbituric acid Reg. 468655; 510907 Syn. baylinal; baytenal; baytinal; buthalitone; narkogen (sodium salt); thiaibutone; transithal; ulbreval. Index BARBITURATES (68) 4 allyl mercaptomethyl penicillin see penicillin 0 23 5-allyl-l-methoxy-2,3-(methylenedioxy) benzene Reg. 607910 Syn. myristicin Index ETHERS, CYCLIC (67) C^O ^o-^^>-CHiCH=CW: 2-allyloxy-3-methylbenzamide Index ANALGESICS AND ANTIPYPETICS (IM) (68) l-(o-allyloxyphenoxy)-3-isopropyl- amino-2-propanol HC1 Reg. Syn. CIBA 39,089-Ba Index SYMPATHOLYTICS (68) 2-(4-a 1ly1-2-methoxyphenoxy)-N,N- diethylacetamide Reg. 305135 Syn. 2-M-4-A; G-29,505; estil; 2-methoxy-4-allylphenoxyacetic acid-N,N-diethylamide. Index ANESTHETICS (Bl) (68) AMIDES (Bl) (68) CH2-CH=CH 0CH3 . . 0CH2CN(C2H5)2 0 3-aIlyl-5-methyloxazolidine-2,4-dione Reg. 526352 Syn. malidone Index OXAZOLES 5-allyl-5-neopentylbarbituric acid Reg. 561831 Syn. censedal; nealbarbitone; nevental. Index BARBITURATES (68) 0 Allylsate A garlic extract in alcohol solution used in the treatment of giardiasis. Index GARLIC (Bl) (68) PLANT EXTRACTS (68) prov. 5-allyl-5-sec-butylbarbituric acid Reg. 77269; 115446 Syn. butalbital; dormal; lotusate; ■ talbutal. Index BARBITURATES (68) H / xN-< NCH-CH1CH3 3-(allylsulfinyl)-alanine Reg. 556274 Syn. alliin Index ALANINE_(68) allylthiourea Reg. Syn. aminosine Index THIOUREA (68) allyrgal see mersalyl-theophylline N-allylnoroxymorphonehydrochloride Reg. 357084 Index NARCOTIC ANTAGONISTS (Bl) (68) ALKALOIDS (Bl) (68) /cM«.,CA^Ctta..t\££ alnico an alloy of aluminum, nickel.and cobalt used in the manufacture of magnets. Index ALLOYS (IM) (68) ALUMINUM (Bl) (6S) NICKEL ' (Bl) (68) COBALT (Bl) (68) 24 alodan see MEPERIDINE Aloinoside B A glycoside from Aloe Index GLYCOSIDES (66). Alotec see orciprenaline aloxiprin Syn. palaprin A polymeric condensation product of aluminum oxide and o-acetyl- salicylic acid. Index POLYMERS (66) alphadryl see l-(2-dimethylaminoethoxy)-l,l- diphenylethane ALPHAPRODINE (D6) (65) ---- Reg. 77203 Syn. Nu-1196; 1,3-dimethy1-4- phenyl-4-piperidyl propionate; *-l,3-dimethyl-4-phenyl-4- propionoxypiperidine; Nisentil, An analgesic. ch, alphosyl A lotion containing allantoin 6c coal tar extract used in the therapy of psoriasis. Index HYDANTOBJS, (Bl) (68) COAL TAR ' (Bl) (68) ALLANTOIN (prov.) alstonidine Reg. 1354263 An alkaloid extracted from root- bark of Alstonia constricta. Index ALKALOIDS (68) altafur see 5-(4-morpholinylmethyl)-3- (5-nitro-2-furfurylideneamino)- 2-oxazolidinone Altamin A preparation for a reducing diet containing egg and milk protein, fat, carbohydrates, vitamins and salts, in 900 calorie doses. Index DIET, REDUCBIG (66) alternariol Reg. 641383 A biphenyl compound from the fungus Alternaria tenuis. Index BIPHENYL COMPOUNDS (68) alternariol trimethyl ether Index BIPHENYL COMPOUNDS (68) alterton see phenaglycodol alubar Reg. MX8057678 Index CONTRAST MEDIA (68) Al-U-Creme see aluminum hydroxide gel aludrine see ISOPROTERENOL 25 Aludrox Reg. 115515 A combination preparation contain- ing antacids, a parasympatholytic, and a barbiturate. It consists of: aluminum hydroxide 0.23 gr.; magne- sium hydroxide 0.081 gr.; ambutonium 0.0025 gr.; and, butabarbital 0.008gr. Index ANTACIDS (Bl) (68) BARBITURATES (Bl) (68) * PARASYMPATHOLYTICS (Bl) (68) aluminum glycinate, basic Reg. 140910 Syn. alglyn; alzinox; aspogen; dihydroxy aluminum aminoacetate; dihydroxy aluminum glycinate. Index GLYCINE (Bl) (68) ALUMINUM (Bl) (68) alvityl V A polyvitamin preparation con- taining vitamins A, B complex, C, D, E and PP. Index VITAMINS (68) Alvodine see piminodine alyt see agnolyt alzinox see aluminum glycinate, basic Amadil see ACETAMINOPHEN amanozine see 2-amino-4-anilino-s-triazine (HC1) aluminum hydroxide gel Reg. 10361510 Syn. alkagel; al-u-creme Index ANTACIDS A1(0H). Alupent see orciprenaline ilurate see 5-allyl-5-isopropyl barbituric acid Alusac Polymerized complex of sucrose and aluminum hydroxide. Index ANTACIDS (68) alvinine see 2-diethylaminoethyl 3-phenylsal- icylate K-amanitin Reg. A mycotoxin found in the toadstool Amanita phalloides. Index MYCOTOXINS (68) AMANTADINE (D3) (68) Reg. 665667 Syn. EXP-105-1; 1-Adamantanamine (hydrochloride); Symmetrel. An antiviral agent. ua amar ine see 2,4,5-triphenyl-2-imidazoline ambazone see (4-oxo-2,5-cyclohexadien-i- ylideneamino)-guanidine thiosemi- carbazone 26 AM3EN0NIUM CHLORIDE (D5) (65) Reg. 115797 Syn. WIN-S077; N,N'-bis-2-[(chloro benzyl)diethylammonium chloride}- ethyloxamide; N,N'-bis(2-diethyl- aminoethyl)oxamide bis-2-chloro- benzylchloride; myorgal; mysuran chloride; mytelane; mytelase chlor ice; [bxalylbis(iminoethyl)|]bis (p- chlorobenzyl)diethylammonium chlor idej; [oxaly!bis(iminoethylene)3bi ^(o-chlorobenzyl)diethylammonium^d ,chloride. A cholinesterase inhibitor, resemb in action neostigmine, used in the management of myasthenia gravis. tjt. crtvc.H3 0 0 , • c«»cH\ c^- UlCHi CHtCW^ L^ s i- ling Id amberlite XE-96 see quinine carbacrylic resin Ambilhar see l-(5-nitrothiazol-2-yl)- imidazolin-2-one Ambosex A combination preparation containing 40 micrograms of ethinyl estradiol and 4 mg. of methyltestosterone in each tablet. Index ETHINYL ESTRADIOL (Bl) (68) METHYLTESTOSTERONE (Bl) (68) ambovegin A mixed preparation containing Pseudo-Cinchona africana alkaloids, Secale extracts, atropine, caffeine and aminopyrine. Index ANALGESICS AND ANTIPYRETICS (IM) (68) ALKALOIDS (Bl) (68) ATROPINE (Bl) (68) CAFFEINE (Bl) (68) AMINOPYRINE (Bl) (68) PLANT EXTRACTS (NB1) (68) ambozim A combination preparation of trypsin and chymotrypsin used for intra- musclar injection. Index CHYMOTRYPSBJ (Bl) (68) TRYPSB* (Bl) (68) ambistrin Equal parts of streptomycin and dihydrostreptomycin. Index STREPTOMYCIN • (Bl) (68) DIHYDROSTREPTOMYCB* (Bl) (68) ambodryl see p-bromodiphenhydramine ambramycin see TETRACYCLINE ambrazil A combination preparation containing tetracycline and a sulfonamide mix- ture of sulfacetamide, sulfadiazine and sulfamerazine. Index TETRACYCLINE (Bl) (68) SULFONAMIDE MIXTURES (Bl) (68) ambolin • . a carbutamide - choline bitartrate preparation. Index CARBUTAMIDE (Bl) (68) CHOLINE (Bl) (68) ambutonium bromide. see (3-carbamyI-3,3-diphenylpropyl) ethyldimethyl ammonium bromide ambonestyl see N-(2-diethylaminoethyl)-iso- nicotinamide Amenoron see ETHBTYL ESTRADIOL amethocaine see TETRACAINE 27 amethone see amolanone N-amidinoglycine see glycocyamine amethopterin see 4-amino-lO-methyl-pteroyl- glutamic acid ametocame see TETRACAINE amfrecin see sodium lauryl sulfate Amicar see AMINOCAPROIC ACID amicetin Reg. 514716 Index ANTIBIOTICS (68) amidazophen see AMINOPYRINE 9-(p-amidinobenzyIidene)-fluorene Syn. paranylene Index FLUORENES (68) amidinomycin see N-(2'-amidinoethyl)-3-amino- cyclopentanecarboxamide amidomycin Reg. 552330 A new antibiotic from Streptomyces PRL 1642. Index ANTIBIOTICS (68) N-amid ino t aur ine see taurocyamine amid on see METHADONE (may also be used to mean starch, especially in French journals.) amidone see METHADONE Amidopyrazoline see AMINOPYRINE Amidopyrine see AMINOPYRINE N-amid ino-3,5-d iamino-6-chloropyrazine- carboxamide HC1 Reg. 2016888 Index PYRAZBJES (Bl) (67) AMIDINES (Bl) (67) AMIDES (Bl) (67) N-(2' -amidinoethyl)-3-aminocyclo- pentanecarboxamide Reg. 3572609 Syn. amidinomycin; myxoviromycin. Index ANTIBIOTICS (Bl) (68) CYCLOPENTANE (Bl) (68) AMIDES (Bl) (68) AMIDINES (NBi) (68) u^ a Amidoschwarz A reagent used in the determination of proteins in serum, urine, CS?, etc. • Index INDICATORS AND REAGENTS (Bl) (68 AZO COMPOUNDS (Bl) (68 SULFONIC ACIDS (Bl) (63 __.....NAPHTHALENES______(Bl) (68 Amigen An enzymatic hydrolysate of - casein. Index PROTEIN HYDROLYSATES (Bl) (68) amimycin see OLEANDOMYCBi 28 aminazin see CHLORPROMAZINE amindan see sulfosalicylic acid sulfanil- amide aminitrozol see 2-acetamido-5-nitrothiazole aminitrozole see 2-acetylamino-5-nitrothiazole aminoacetonitrile Reg. 540614 Syn. cyanomethylamine• Index NITRILES (68) UztlCH^C=A/ p-aminoacetophenol see ACETAMINOPHEN 3-(aminoacetyl)-propionic acid see 5-aminolevulinic acid D-AMINOACID OXIDASE (D9) (65) d-arainoacid:02oxidoreductase (de- aminating); IUB.1.4.3.3 It has been located in human brain stem, kidney and liver; its func- tion remains unknown. amino acid polymerase An enzyme system in E. coli z catalyzing the incorporation of amino acids into peptides and proteins. Index ENZYMES (Bl) (68) AMINO ACIDS (Bl) (68) 5-aminoacridine Reg. 90459 Syn. acrisan; 9-aminoacridine. An external antiseptic; a morphine antagonist. Index ACRIDINES (Bl) (68) ANTI-INFECTIVE AGENTS (Bl) (68) 9-aminoacr id ine see 5-aminoacridine 9-aminoacridinium 4-hexylresorcinolate Reg. 1839130 Syn. acrisorcin; Akrinol. A compound formed through the chemical union of 9-aminoacridine and 4-hexylresorcinol. It is usea in the treatment of fungal di- seases. Index RESORCINOL (Bl) (68) ACRBJINES (Bl) (68) 2-amino-4-anilino-s-triazine (HC1) Reg. 537177 Syn. W-1191-2; amanozine. A non-mercurial, non-carbonic an'ny- drase inhibitor diuretic. Index DIURETICS (Bl) (68) TRIAZINES (Bl) (68) 0 Hti -*\ H ti 4-aminoantipyrine Reg. 83078 An antipyrine derivative. Index ANTIPYRINE (68) (Bl) PYRAZOLES (68) (Bi) Amino-argin Reg. MX8057689 A preparation of essential amino acids, used in disorders of cereb. metabolism. Index AMINO ACIDS 29 2-amino-4-ar s eno sopheno1 see OXOPHENARSINE p-aminobenzoylaminoacetic acid see AMINOHIPPURIC ACH) o-arainoazo toluene see 4-o-tolylazo-o-toluidine p-aminobenzamidine Reg. Index TRYPSIN INHIBITORS (Bl) (68) AMIDINES (Bl) (68) 4-aminobenzoylglycine see AMINOHIPPURIC ACID D(l)-o(-aminobenzyl penicillin see AMPICILLIN p-aminobenzene-sulfamido-isopropyl- thiadiazole see N'-(5-isopropy1-1,3,4-thiadi- azol-2-yl) sulfanilamide p-aminobenzene-sulfamido-tertiobutyl- thiodiazol see N'-(5-t-butyl-l,3,4-thiadiazol- 2-yl)sulfanilamide p-aminobenzenesulfonamide see SULFANILAMIDE 2-p-aminobenzenesulfonamidoquinoxaline Reg. 59405 Syn. sulfacox; sulfanilamido- quinoxaline; sulquin. Index SULFONAMIDES (68) p-aminobenzenesulfonylguanidine see sulfaguanidine AMINOBENZOIC ACID (D2) (65) Reg. 150130 Syn. p-aminobenzoic acid; PABA; Paraminol; vitamin Bx. Used as a dietary supplement, as an antirickettsial agent, and with accompanying salicylates in rheumatic fever therapy. NH2-/~\-C00H p-aminobenzoic acid see AMINOBENZOIC ACID 5-amino-l,3-bis(beta-ethylhexyl)-5- me thylhexahydropyr imid ine see hexetidine 4-amino-3-butoxy-^-diethylaminoethyl benzoate Syn. benoxinate; 3-butoxyprocaine; dorsacaine; novesin. Index ANESTHETICS, LOCAL AMINOCAPROIC ACID (D7, D10) (64) Reg. 60322 Syn. Amicar; £-aminocaproic acid; aminocapronic acid; Caprocid; •vEACA; Ipsilon. An antifibrinolytic agent. MI,-(C MAs'"""* £-aminocaproic acid see AMINOCAPROIC ACID aminocapronic acid see AMINOCAPROIC ACID 30 4-amino-5-carboxamido-7(D-r ibofur an- osyl)-pyrrolo-p,3-d]pyrimidine Syn. sangivamycin. A nucleoside antibiotic. Index ANTIBIOTICS (Bl) (68) NUCLEOSIDES (Bl) (68) o D-4-amino-4-carboxy-n-butyl penicillin see synnematin B N-epsilon-(DL-2-amino-2-carboxyethyl)- L-lysine Syn. lysinoalanine. New amino acid formed on alkaline treatment of ribonuclease. Index DIPEPTIDES (3-amino-3-carboxypropyl)-dimethylsul- fonium chloride see vitamin U 2-amino-4-(m-chloroanilino)-1,3,5- triazine Reg. 718434 Syn. R-37 A heterocyclic compound with diur- etic properties. Index ANILINE COMPOUNDS (Bl) (68) TRIAZINES (BO (68) 2 -amino -5 -chlorobenzoxazole see ZOXAZOLAMINE 4-amino-5-chloro-N-^2-(diethyIamino) ethyl^-O-anisamide •Syn. Metocloramide Index AMB3ES (67) 4-amino-6-chloro-N,N'-dimethyl-m- benzenedisu1fonamide Syn. K-572. A sulfonamide diuretic. Index SULFONAMIDES (Bl) (68) DIURETICS (Bl) (68) 6-amino-2-(2-chloroethyl)-2,3-dihydro- 4H-l,3-benzoxazin-4-one • Syn. ICI-350. An antirheumatic compound. Index ANALGESICS AND ANTIPYRETICS (IM) (68). OXAZINES (Bl) (68) •HCJc 2-amino-l-(p-chlorophenyl)-2-methyl- propane see chlorphentermine 6-aminochrysene Reg. 2642980 A carcinogenic derivative of benzphenanthrene used for the treatment of splenomegaly. Index PHENANTHRENES (Bl) (68) CARCINOGENS (Bl) (68) aminocordin see NIKETHAMIDE 4-amino-5-cyano-7-^-D-ribofuranosyl- pyrrolo[2,3-d3-pyrimidine Reg. Syn. 7-cyano-7-deazaadenosine; toyocamycin. Index ANTIBIOTICS, ANTINEOPLASTIC (IM) (68) PYRIMIDINES (jflv CJ^RIBOSE J Kx^Jss^1 OCWt, (IM) (68) (NB1) (68) 31 1-aminocyclopentanecarboxylic acid Reg. 52528 Syn. NSC-1026 A cycloparaffin with minimal antineoplastic properties. Index CYCLOPENTANE (Bl) (68) AMINO ACIDS (IM) (68) aminodal see AMINOPHYLLINE pC-(D-6-amino-6-deoxyglucopyranosyl) deoxystreptamina Reg. An antibacterial degradation product of kanamycin. Index ANTIBIOTICS (68) Ctf^t. oH OM *--' 17-amino derivative of progesterone see 17-aminopregn-4-ene-3,20-dione 4-amino-3',5'-dibromobenzenesulf- anilide $yn. bemural Index SULFONAMIDES (68) 5-amino-2,3-dihydro-l,4-phthalazinedione Reg. 521313 Syn. 3-aminophthalic acid hydrazide; 3-aminophthalhydrazide; luminol. A heterocyclic chemiluminescent . compound that has been used as a 'diuretic and as an indicator and reagent. It has also been shown to be effective in promoting wound healing. Index PYRIDAZINES (68) CO: 5-amino-l,6-dihydro-7H-/-triazolo (4,5 -dj pyr imid in*- 7 -one see AZAGUANINE 2-aminoethanesulfinic acid Reg. 107357 Syn. hypotaurine. One of the sulfonic acids. Index TAURINE (Bl) (68) SULFONIC ACIDS (Bl) (68) 2-aminoethanethiol see CYSTEAMINE 3-amino-4-dichloroarsinophenol Reg. 536298 Syn. 3-amino-4-hydroxyphenyl- dichloroarsine; dichloromaphar- sen. An oxophenarsine derivative. Index OXOPHENARSINE (68) 2-amino-1,3-d ichloropropane A cytotoxic nitrogen mustard-like compound. Index PROPYLAMINES (Bl) (68) ANTBJEOPLASTIC AGENTS (Bl) (68) C1 -CH2 -CHNH2 -CH2 -C1 c-Q % *- M Mi l-m-aminophenyi.sulfonyl-3-butylurea Reg. Syn. sucrida; SB 1. An oral antidiabetic, closely related to carbutamide which has a p-amino group instead of a m-amino group. Index ANTIDIABETICS (68) 4 0-SO^H-^^CHiCil, ck/«3 3-aminoph thalhydr a z id e see 5-amino-2,3-dihydro-l,4- phthalazinedione .O ft* 2-amino-4-picoline camphorsulfonate Reg. Syn. Varunax Index SYPATHOMIMETICS (Bl) (68) PICOLINE (Bl) (68) 17-aminopregn-4-ene-3,20-dione Syn. 17-amino derivative of progesterone. Index PREGNANES (68) V aminopromaz ine see 10-[2,3-bis(dimethylamino) propy^ phenothiazine 3-aminophthalic acid hydrazide see 5-amino-2,3-dihydro-l,4- ph thala z ined ione aminopropionitrile (prov.) Syn. ^-aminopropionitrile. A cyanide which induced lathyrism. Index NITRILES (68) 38 p-aminopropiophenone Reg. 70699 A methemoglobinemizing cyanide antidote. Index ANTIDOTES (IM)(68) PR0PI0PHEN0NES (Bl)(68) o 4-aminopteroyl-triglutamic acid Reg. Syn. amino-teropterin Index FOLIC ACID (68) 2-aminopurine-6-thiol see THIOGUANINE A) 14, p-(2-aminopropyl)-phenol Syn. hydroxyamphetamine; paredrine; Pedrolon. Index SYMPATH0MB1ETICS (Bl) (68) PHENOLS (Bt) (68) l-(4-amino-2-propylpyrimidin-5- ylmethyl)-2-picolinium chloride HC1 Reg. 137882 Syn. amprolium Index PICOLINE (68) (IM) ANTIPROTOZOAL AGENTS (68)(Bl) 6-amino-9-D-psicofuranosyl purine . Reg. Syn. psicofuranine Index ANTIBIOTICS (68) c^°* ^^Mbiotics 9(7): 419, Jul 59 AMINO-PTERIN (D4) (59) Reg. 54626 Syn. 4-aminofolic acid 4-aminopteroylaminoadipic acid An antagonist and a closely related compound of folic acid, the differ- ence being that instead of the glutamic acid part of folic acid it has an adipic acid (amine) part. Index FOLIC ACID ANTAGONISTS (68) 2-aminopurine-6(lH)-thione see THIOGUANINE 4-aminopyra zolopyr imid ine Syn. APP An adenine analogue which suppres- ses growth of Escherichia coli and Bacillus cereus. Index PYRAZOLES (Bl) (68) PYRB1IDINES (Bl) (68) 4-J5-amino-3-(4-pyridyl)-l-pyrazolyl| - 1-methylpiperidine see 2-N-methylpiperidyl-(4) -3-amino-|, 5-(4,-pyridyl)-pyrazole HC1 AMINOPYRINE (D6) (60) Reg. 58151 Syn. amidazophen; amidopyrazoline; amidopyrine; aminophenazone; 4- dimethylaminoantipyrine; 4-dimethyl- amino-2,3-dimethyl-l-phenyl-3- pyrazolin-5-one; 4-dimethylamino- 1,5-dimethy1-2-phenyl-3-pyrazolone; dipyrine; Novamidon; Pyramidon. An analgesic and antipyretic. cc^V aminopyrine 8-hydroxyquinoline-5- sulfonic acid Syn. causyth. An analgesic 6c antipyretic. Index AMBJOPYRINE (Bl) (68) QUINOLINES (Bl) (68) SULFONIC ACIDS (Bl) (68) 39 aminopyrine sodium sulfonate Syn. dipyrone; metaraizol; metami- zolum; methampyrone; methylmelubrine; nartate; neomelurbrin; novaldin; novalgin; novaminsulfon; Pyralgin; sodium 1,5-dimethy1-2-phenyl-4- dimethylamino-3-pyrazolone sulfonate. Index AMINOPYRINE (Bl) (68) SULFONIC ACIDS (Bl) (68) 3-amino-4H-pyrrolo [3,4-cj isoxazole- 5(6H)-carboxylic acid, ethyl ester Syn. CL 65263 An inhibitor of tyrosine hydroxylase. Index PYRROLES (Bl) (68) OXAZOLES (Bl) (68) ENZYME INHIBITORS (Bl) (68)* aminorex see 2-amino-5-phenyl-2-oxazoline 2-amino-N-ribosylacetamide-5'- phosphate transformylase Syn. glycinamide ribotide transformylase. Index TRANSFERASES (68) p-aminosalicylic acid Reg. Syn. aminosalyl Index AMINOSALICYLIC ACID (68) N-(3-aminosalicyloyl)-L-threonine Syn. antimycic acid Index THREONINE (68) aminosalyl see p-aminosalicylic acid aminosidine An antibiotic from a species of Streptomyces isolated from Tuscan soil. Used in the therapy of giardiasis. Index ANTIBIOTICS (68) aminosine see allylthiourea Aminosol fructose ethanol A parenteral solution containing in each 1,000 ml: Amino-acids (Aminosol-VItrum) 33 g.; fructose 150 g.; and ethanol 25 g. Index AMINO ACIDS (Bl) (68) FRUCTOSE (Bl) (68) ALCOHOL, ETHYL (Bl) (68) 2-amino-5-sulfanilylthiazole Reg. 473303 Syn. aminothiadiazolylsulfonamide; thiazolsulfone. Index SULFATHIAZOLES * (68) p-aminosalicylic acid hydrazide Reg. Syn. apacizina; apacizine. Index AMINOSALICYLIC ACID (Bl) (68) HYDRAZINES (Bl) (68) t X3 amino-teropterin see 4-aminopteroyl-triglutamic acid M^VfT}, 40 9-amino-l,2,3,4-tetrahydroacridine Reg. 321642 Syn. tacrine; tetrahydroaminacrin; THA. Index ACRIDINES (67) 2.(3-amino-2,4,6-triIodobenzyl)-butyric acid c68' 9 ethvl-3-(3-amino-2,4,6-tri- ^phenyl-propionic acid; *>pagnos, Ar-contrast medium. Index CONTRAST MEDIA (68) 2-aminotetralin see beta-tetrahydronaphthylamine aminothiadiazolylsulfonamide see 2-amino-5-sulfanilylthiazole aminothiols Index SULFHYDRYL COMPOUNDS (Bl)(67) AMINES (Bl) (67) <\-amino -p -t o luenesulf onamide Syn. benzylog; marfanil; sulf- benzamine. Index SULFONAMIDES (68) -androstene- 3>2,17/S-diol androfort see testosterone acetate ANDROGENS (D8) Male sex hormones, substances capa- ble of stimulating the development and functional activity of the male accessory structures and secondary sexual characteristics. Natural an- drogens in man are secreted by the testes, the adrenal cortex and the ovaries. The major androgen is testosterone. ______________ androisoxazole see 17/-hydroxy-17«-methylandro- stane-(3,2c)-isoxazole ____ androlone see STANOLONE andromedotoxin Reg. 1354365 Index VASODILATOR AGENTS 5/3-andr os tane-3 «:, 17-<-d io 1 Syn. S-x'-androstane-S*,17^-diol. The 5/3 isomer is isolated from normal human urine. The 5< isomer is a metabolite of testosterone by prostate. .Index ANDROSTANES (Bl) (68) STEROLS (NB1) (68) 17-HYDR0XYC0RTIC0STER0IDS. (B (68) (68) HO andro stane-3/3-o 1-17-one see epiandrosterone androstane-17^ -ol-3-one see STANOLONE ANDROSTANES (D2) (68) Steroids with methyl groups at C-10 and C-13 and with no more than one carbon at C-17. Kay include: Any degree of hydrogenation; Hetero sub' stitution in any of the rings; Any non-carbon derivatives except as specified. 46 androstanolone Reg. 521186 Syn. 17#-hydroxy~5«-androstan-3-one dihydrotestosterone Index STANOLONE (68) &. -androstene-3/3,17-diol Reg. 521175 17oc6c 17/3 epimers are found in normal human urine. Index ANDROSTANES (Bl) (68) STEROLS (NB1) (68) 17-HYDR0XYC0RTIC0STER0IDS (Bl) OH (68) A5-androstene-3<*-ol-17-one Reg. Syn. dehydrcandrosterone. An androgen. Index ANDROGENS (Bl) (68) ANDROSTANES (Bl) (68) 4-androstene-17/-ol-3-one-17*e»-3- propionic acid gamma lactone Reg. An aldosterone antagonist. Index ANDROSTANES (Bl) (68) ALDOSTERONE *antagonists(Bl) (68) androstenol (D2,D8) provisional Reg. Syn; androst-16-en 3 -ol. A urinary androgen. Index ANDROGENS (Bl) (68) ANDROSTANES _ (Bl) . (68) A5-androsten-33-ol-17-one see DEHYDROEPIANDROSTERONE androst-4-ene-6/3,17/*-diol-3-one see 6/3-hydroxytestosterone 3^-androsterone see epiandrosterone Androtex see 4-androstene-3,17-dione 4-androstene-3,17-dione Reg. 63058 Syn. Androtex. n Index ANDROSTANES 17-KET0STER0H>S anectine see SUCCINYLCHOLINE (IM) (68) (IM) (68) anergen see 10-(2-dimethylaminoethyl)- phenothiazine 4-androstene-ll/-ol-3,17-dione Reg. An androgen secreted by the adrenals. Index ANDROGENS (IM) (68) ANDROSTANES (IM) (68) Anergex a Rhus extract, "the exact compo sition of which has not yet been determined, prepared from Toxico• dendron quercifolia (Rhus)"; pro duct of Mulford Colloid Lab., Philadelphia. It is supposedly useful in allergic diseases. Index PLANT EXTRACTS (68) 47 anervan Syn. Kabi 805 A caffeine - chlorcyclizine - ergotamine tartrate - mepro- bamate preparation used in the therapy of migraine. Index CAFFEINE ERGOTAMINE MEPROBAMATE % CHLORCYCLIZINE prpv. anesthesin see BENZOCAINE (IM) (68) (IM) (68) (IM) (68) (NIM) (68) ane tho cur ar ium see b Is-p-dime thy Iamino - e thoxypheny1-3-methyIbutane diiodome thane anetholetrithione see 5-(p-methoxyphenyl)-l,2- dithiole-3-thione aneural see MEPROBAMATE (68) aneurin disulfide see thiamine disulfide aneuxo1 see AMBJOPYRINE anginasin An antiseptic aerosol preparation used mainly in therapy of the in- fections of the upper respiratory tract. It contains iodine, camphor, rosemary oil and ammonia in alcohol. Index ANTI-INFECTIVE AGENTS (68) angiotanase see ANGIOTENSINASE ANGIOTENSIN AMIDE (D4) Reg. 53736 Angiotensin amide is a nonproprie- tary name adopted by the World Health Organization and the USAN Council to designate a synthetic substance which, chemically,iis a minor structural variant of the naturally occurring angiotensin II, It is N-Cl-CN-(N-(N-fN-(N2-aspara- ginylarginyl) valiylj tyrosyU valyl] - histidylj prolyl]-3-phenylalanine. ANGIOTENSINASE (D9) (68) Proteolytic enzymes which are capable of destroying angiotensin. Syn. angiotanasej angiotonase; hypertensinase. angiotensinogen Syn. hypertensinogen; renin-sub- strate. The precursor of hypertensin. Index ALPHA GLOBULIN (Bl) (68) ANGIOTENSBJ AMIDE (Bl) (68) angiotonase see ANGIOTENSINASE angiotrofine a 2-benzimidazoline-2-phenylbenzyl- aminomethylimidazoline methane- sulfonate-tetraethylammonium bromide preparation. Index BENZB1IDAZ0LES (Bl) (68) B1IDAZ0LES (Bl) (68) TETRAETHYLAMMONIUM COMPOUNDS (Bl) (68) angiopac see ethyl diiodostearate angocin An Echinacea and Tropaeolum maius extract. A homeopathic remedy. Index PLANT EXTRACTS prov. (68) 48 angustmycins (A,B,C) Antibiotics from Streptomyces hygroscopic var. angustmyceticus. Index ANTIBIOTICS (68) anhydro-4-epi-tetracycline Reg. Syn. anhydroauatrimycin An epimer of tetracycline Index TETRACYCLINE ANHYDRIDES (D2) (66) Compounds (usually acids) from which water has been removed; includes ring compounds, such as maleic anhydride, phthalie anhydrides, etc. v. 6 R-c 'S R'-cl or N ,N -anhydrobis(^-hydroxyethyl)- biguanide Syn. JD-1022; ABOB; vironil; virugon; Virumin; virustat; Wirumin. A guanidine with antiviral proper- ties, which in a preparation called flumidin (q.v.) has been used in treating influenza and herpes zoster. Index BIGUANIDES (Bl) (68) ANTIVIRAL AGENTS (Bl) (68) KH it N,N'-anhydro-bis-(beta-hydroxyethy1)-^ biguanide HC1 Syn. spenitol Index BIGUANIDES (Bl) (68) ANTIVIRAL AGENTS (Bl) (68) HK M anhydroformaldehyde aniline see l,3,5-triphenylhexahydro-8' triazine anhydrohydroxy-19-norprogesterone acetate A commercial preparation called Duogyn contains 5 mg. of anhydro- hydroxy-19-norprogesterone acetate and 0.01 mg. ethynyl- estradiol in each dragee. Index PROGESTATIONAL HORMONES (Bl) (68) ETHBTYL ESTRADIOL (Bl) (68) Anhydron see 6-chloro-3,4-dihydro-3- (5-norbornen-2-yl)-7-sulfamoyl- 1,2,4-benzothiadiazine-l,1-dioxide anhydroquatrimycin see anhydro-4-epi-tetracycline anicaine see diphenylacetic acid 2-piperi- dinoethyl ester anileridine (D6) provisional Reg. 144149 Syn. l-(p-aminophenethyl)-4- phenylisonipecotic acid ethyl ester; ethyl l-(4-aminphenethyl)- 4-phenylisonipecotate; leritine; nipecotan. Index ANALGESICS AND ANTIPYRETICS (Bl) (68) ISONIPECOTIC ACIDS (Bl) (68) C4s£42oc /-\X><^'0-^ 49 3-anilino-2,10-dihydro-2-imino- 10-phenylphenazine Reg. 4733215 Syn. B-283. A heterocyclic dye compound. Index PHENAZBJES (Bl) (68) DYES (Bl) (68) 0 still jj-l* 0 l-(2-anilinoethyl)-4-phenyliso- nipecotic acid ethyl ester Reg. Syn. Win-13,797; ethyl 4-phenyl-. l-(phenylaminoethyl)-piperidine- 4-carboxylate. Index ISONIPECOTIC ACIDS (Hi) (68) ANALGESICS AND ANTIPYRETICS (IM) (68) C.ocU2Ctf3 ^■O .^crt l-(3-anilinopropyl)-4-phenylisonipecotic acid ethyl ester (ethanesulfonate) see piminodine anilinothiamine see 2-methyl-4-aminopyrimidyl-5- methylaniline anirrit see 5-methyl-5-C2-(l,2-dibromophenyl) ethylj-hydantoin anisindione see 2-p-anisyl-l,3-indandione anisomycin see 2-p-methoxyphenylmethyl-3- acetoxy-4-hydroxypyrro1idIne anisotropine methylbromide (D5) prov. Reg. 80502 Syn. 8-methytropinium bromide-2- propylvalerate; octatropine methylbromide; 2-propylpentanoyl- tropinium methylbromide; Valpin. A parasympatholytic used in the treatment of gastrointestinal disorders. Index PARASYKPATHOLYTICS (Bl) (68) NORTROPANES (Bl) (68) AMMONIUM COMPOUNDS (Bl) (68) --p-anisyl-l,3-indandione Reg. Syn. anisindione; miradon. An anticoagulant. Index ANTICOAGULANTS (Bl) (68) INDENES (Bl) (68) anisidine Reg. Index ANILINE COMPOUNDS (67) ocU Anovlar A combination of ethinyl estradiol and norethindrone. Index ETHINYL ESTRADIOL (Bl) (63) NORETHINDRONE (Bl) (68) ANR formula A nicotinic acid - vitamin A - vitamin B 2 preparation. Syn. provasin Index VITAMIN A (Bl) (*3) NICOTINIC ACID (Bl) (63) RIBOFLAVBJ (IM) (63) 50 ansadol see salicyl anilide ansolysen see PENTOLBJIUM TARTRATE antaethyl see disulfiram Antallergan see pyrilamine Antallin see EDTA Antamine see pyrilamine antapentan see 3,4-dimethy1-2-phenyl-1,4- tetrahydro-oxaazine Anteron A gonadotropin from the serum of a pregnant mare used to induce ovulation. Index GONADOTROPINS, EQUBIE (68) antheraxanth in Index CAR0TEN0B)S (68) antheridiol Reg. A sex hormone isolated from the water mold Achlya bisexualis (Phycomycetes). Index SEX HORMONES (Bl) (68) PHYCOMYCETES (Bl) (68) anthiomaline see antimony sodium thiomalate anthiphen see 2,2'-dihydroxy-5,5,-dichloro d iphenylmethane antaphron see methylpolysiloxane antazoline see 2-(N-benzyl-anilinomethyl)- 2-imidazole anternesin Reg. 5768503 A 2-(benzohydryloxy)-N,N-dimethyl- ethylamine 8-bromotheophyllinate - chlorobutanol preparation. Index THEOPHYLLINE (Bl) (68) ETHYLAMINES (Bl) (68) Anthisan see pyrilamine anthralin see 1,8,9-antjhratriol anthramycin An antitumor principle produced 1 from the fermentation broth of Streptomyces refuineus variety thermotolerans. Index ANTIBIOTICS, ANTBJEOPLASTIC (IM) (68) antepar see piperazine citrate 1,8,9-anthratriol Syn. anthralin; cignolin; 1,8-dihydroxyanthranol; aithranol Used in the treatment of dermatitis Index ANTHRACENES (jm) (68) and ANTIFUNGAL AGENTS (Bl) (68) or ANTI-INFECTIVE AGENTS, LOCAL (IM) (68) 51 anthyrin This is a potassium perchlorate - reserpine preparation. Index PERCHLORIC ACH>S (IM) (68) RESERPINE (Bl) (68) ANTIDOTES (D8) (63) Remedies for counteracting poisons antiduol see MEPERIDINE antibiolymphins see lymphotrophic antibiotics antibiotic 899 see staphylomycin antibiotic 900 see streptogramin antibiotic X-948 see under numbered compounds antibiotic 1600 see amminosidine antibiotic 1943 see under numbered compounds antibiotic 23572 see under numbered compounds ANTIBIOTICS, ANTIFUNGAL (D3) (68) , Antibiotics whose activity is specific for fungi. ANTIBIOTICS, ANTINEOPLASTIC (D4,D3)(68) Antibiotics which suppress or destroy tumor growth. ANTICHOLESTEREMIC AGENTS (D4) (68) Agents which cause reduction of blood cholesterol levels and have been postulated to be useful in the prevention of arteriosclerosis; also known as hypochloesteremic agents. .: antielastase A protease antagonist. Index PEPTHJE HYDROLASES *antagonists (68) anti-ethyl see DISULFIRAM ANTIFIBRINOLYTIC AGENTS (D4) (68) Agents which prevent the activa- tion of the fibrinolytic system and are used, consequently, in the treatment of hemorrhage asso- ciated with excessive fibrinolysis, antifoam A see dimethylsiloxane antiftihnon An cuphorizing CNS stimulant combination, containing ephedrine, caffeine, acetophenetidin, carbromal, nitric acid esters and Convallaria glucosides. Used in the therapy of mcteorotropic diseases, unfavorable reactions to weather, in depression, vegetative neurosis, etc. Index EPHEDRINE (IK) (68) CAFFEINE ((IM) (63) PHENACETIN (IM) (68) GLYCOSIDES (Bl) (68) ANTIFUNGAL AGENTS (D3) (67) Agents destructive to fungi, or suppressing their reproduction or growth; effective against fungus infections. 52 anti-.istrin sec 2-phcnyl-2-(2-pyridyl) thioacetamide antihisan see pyrilamine antihistamine-penicillin This is a l-p-chlorobenzyl-2- pyrrolidylmethylbenzimidazole - penicillin preparation. Index BENZIMIDAZOLES (Bi)((68) PENICILLIN (Bl)(68) antihydral see METHENAMINE ANTI-INFECTIVE AGENTS, LOCAL (D3)(67) Agents which are applied locally to counteract infection; they include antiseptics, germicides, bactericides, fungicides, etc., when applied to tissue, but not DISINFECTANTS, which are applied to Inanimate objects. May include surface active agents, such as hexachlorophene, which are merely . bacteriostatic. ANTI-INFLAMMATORY AGENTS (D4, D5)(65) Agents which alter the normal inflammatory responses of the body; they suppress not only the "useless" reactions which are characteristic of many connective tissue disorders but also those inflammatory responses through which the body resists and walls off invading microorganisms; they also slow the development of granulation tissue and may delay healing of wounds and fractures. ANTI-INFLAMMATORY AGENTS, TOPICAL ' (D5) (68) Anti-inflammatory agents (q.v.) used in the treatment of inflam- matory, allergic and pruritic skin conditions; also in anogeni- tal pruritus and other inflam- matory conditions of the lower intestinal and genitourinary tracts. They are applied direct- ly to the affected area as creams, ointments, lotions, aerosol solu- tions, etc. antikinetotic drugs are motion sickness remedies Antikol see DISULFIRAM antimicina see ISONIAZID antimony sodium thiomalate Reg. Syn. anthiomaline Index ANTB10NY (68) antimycic acid see N-(3-aminosalicyloyl)-L-threonine ANTIKYCIN A (D3) (65) An antibiotic substance produced by Streptomyces spp.; it exhibits a characteristic ability to inhi- bit oxidative phosphorylation in mitochondria. anti-5-nitro-2-furaldoxime Syn. micofur; nifuroxime. Index NITROFURANS (68) 53 antipar see dicthazine anti-perinuclcar factor An antibody of the 7S gamma glob- ulin type directed against the "kcratohyaline" granules present in epithelial cells of human buccal mucosa. Nature of granules* not known but thought to be pre- cursor of keratin. Anti-perinucle- ar factor does not seem to be re- lated to the anticytoplasmic factors found in sera of patients with systemic lupus erythematosus. Index AUTOANTIBODIES (68) antiphlogistic hormones are those such as hydrocortisone, cortisone and other adaptation hormones. antiphlogistine An antiphlogistic preparation containing iodine solution, boric acid, glycerol, salicylic acid, methyl salicylate, kaolin powder, peppermint oil & eucalyp- tus oil. Index ANTI-INFLAMMATORY AGENTS ' (68) antipodes (of a compound) these are optical isomers compounds which differ only in the rotation of polarized light (and consequently in their spatial arrangement); D & L, + & -, or dextra and levorotatory forms. ANTIPROTOZOAL AGENTS (D3) (68) Agents that destroy protozoa, or check their growth or reproduc- tion; includes trichomonacides. antipsorinticum An ointment containing tri- chlorocthylamine and petrolatum or autol oil. It is used in the treatment of psoriasis. Index NITROGEN MUSTARD COMPOUNDS (IM) (63) PETROLATUM (IM) (68) ANTIPYRINE (D6) (60) Reg. 60800 Syn. Analgesine; 2,3-dimethyl-J.- phenyl-3-pyrazolin-5-one; 1,5- dimethyl-2-phenyl-3-pyrazolone; Parodyne; Phenazone. An analgesic and antipyretic. ANTIRETICULAR CYTOTOXIC SERUM (D l-> A serum made by inoculating hors^ with an extract of spleen and bo»._ marrow: said to have, in srr.ali doses, a stimulating effect on zZ^ reticuloendothelial system, and in large doses a cytotoxic effect on that system. antistine see 2-(N-benzyl-anilinomethyi)-2- imidazoline antistrept see SULFANILAMIDE antistreptohyaluronidaso see streptococcal antihyal- uronidase 54 ANTITOXINS (D7) (68) Antibody to the toxin of a microorganism, usually the bacterial exotoxins, that combines specifically with the toxin, in vivo and in vitro, with neutralization of toxicity. antitrichomonal agents (prov.) Agents used for the treatment of vulvovaginitis through specific action against the causative organism, Trichomonas vaginalis. Index PARASITICIDES (LM) (68) TRICHOMONAS INFECTIONS (Bl) (68) alpha-1-antitrypsin A protease inhibitor occurring in the alpha globulin fraction of plasma. Index TRYPSIN INHIBITORS (IM) (68) ALPHA GLOBULIN (Bl) (68) anti-ulcer factor see vitamin U ■ .•■'• ANTIVENINS (D7) (68) Venom-neutralizing globulins obtained from serums of animals immunized against animal or insect venoms. antivcrt This is a meclizine-nicotinic acid preparation. Index MECLIZINE (Bl) (68) NICOTINIC ACID (Bl) (68) antiycast factor Syn. AYF. A compound conatining 2 hepta-ene antibiotics isolated from Streptomyces aureofaciens; it has antifungal and antiyeast actions. Index ANTIBIOTICS, ANTIFUNGAL (68) antoxol see DIMERCAPROL Antrenyl see oxyphenonium bromide antrycide see quinapyramine antrypol . see SURAMIN antu see <<-naphthylthiourea anturan see SULFINPYRAZONE anusol The chemical components are: BioOo, Resorcinol, Bismuthoxy- iodide, zinc oxide, peru balsam, boric acid, hydrocortisone acetate (Cortisol). Index HYDROCORTISONE, TOPICAL (67) aoxin see bis-fp-(N-isopropyl-N-methyl- amino)phenyl] -sulfate 6-APA see 6-aminopenicillanic acid apacizina see p-aminosalicylic acid hydrazide apacizine see p-aminosalicylic acid hydrazide apalgin An aminpyrine-urethane preparation. Index AMINOPYRINE (IK) (68) URETHANE (Bl) (6S) t 55 see ACETAMINOPHEN APA? see ACETAMINOPHEN APATITES (Dl) (68) Includes apatite (calcium fluopho- phnte, calcium chlorophosphate) and hydroxyapatite (calcium phosphate hydroxide). Ca3(P04)vCaF2 Ca3(P04)2.CaCl2 3Ca3(P04)2-Ca(0H)2 APB see 5-allyl-5-(l,l-dimethylpropynyl) barbituric acid APC A combination of acetylsalicylic acid with acetophenetidin and caffeine. Index ASPIRIN (Bl) (68) PHENACETIN (IM) (68) CAFFEINE (Bl) (68) apertase see HYALURONIDASE APG see vitamin B 15 APG.H8 see vitamin B 15 H8 apholate sec 2,2,4,4,6,6-hoxahydro-2,2,4,4, 6,6-hcxakis-(aziridinyl)-1,3,5,2/ . 4,6-triazatriphosphorine apidyk see royal jelly apifortyl see royal jelly apiol Reg. 523808 Syn. l-allyl-2,5-dimethoxy-3,4- methylenedioxybenzene. Parsley camphor, a white crystal- line solid with a faint odor of _ . parsley. Liquid apiol is the oleoresin(01eroresina petroselini, USP IX, oil of parsley seed). Formerly employed as an antipy- retic and emmenagogue (Merck Index). Index ETHERS, CYCLIC (68) D-apiose see 3-C-hydroxymethyltetrose apiserum see royal jelly aplysioviolin Reg. A bile pigment isolated from the sea hare Aplysia. Index BILE PIGKENTS (Bl) (68) PORPHYRINS (Bl) (68) APM see acid precipitable material apolamine A combination containing pheno- barbital, atropine sulfate, scopolamine HBr, ethylaminoben- zoate, riboflavin, pyridoxine HC1 and nicotinamide. Used in therapy of vomiting, motion sickness, Meniere's disease with sedative and tranquilizing effects. Index HYPNOTICS AND SEDATIVES (IM)(6S) TRANQUILIZING AGENTS (Bl) (6S) 56 Aponiere see 4-chloro-m-benzenedisulfonamide aprofen see 2-diethylaminoethyl-2,2' diphenylpropionate HC1 apoplectal A combination preparation contain- ing: 7-(2-hydroxyethyl)-theophyl- line, 220 mg. and Aesculus hippo- castanum extract, 250 mg. Index THE0PHYLLB1E (Bl) (68) AESCULUS (Bl) (68) APORPHINES (D2) (69) Parent alkaloid rings having the indicated structure: includes structures having any configuration, any degree of hydrogenation, or any substi- tuents except other fused rings APP see 4-aminopyrazolopyrimidine appendilon see abdomilon aprophen see 2-diethylaminoethyl-2,2' diphenylpropionate HC1 apurinic acid A hydrolysate of desoxyribo- nucleic acid produced by mild acid hydrolysis. Index NUCLEOTB)ES (68) apyrase see ADENYLPYROPHOSPHATASE Aquamephyton Reg. An aqueous colloidal solution containing 10 mg. vitamin K-l in 1 ml. For the treatment of pre- sent or threatened hemorrhage due to overdosage of anticoagulants (not heparin); hemorrhagic disease of the newborn. Index VITAMIN K aprobarbital see 5-allyl-5-isopropyl barbituric acid aprobit Reg. The N%(2-hydroxyethyl)- derivative of promethazine. Index PROMETHAZINE (68) C0GutlO cu 1 ^v ui ■ic 4 Svensk Lakartidn 57(22):1669, 27 May 60 aqua mistol A benzalkonium chloride-phenyl- ephrine -pyri lamine aerosol. Index BENZALKONIUM CHLORIDE (Bl) ^PHENYLEPHRINE (Bl) ANTIHISTAMINICS (Bl) Aquamox see QUINETHAZONE aquasol see VITAMIN A (68) (6S) (66) ■a 57 aquatyl A cathartic preparation contain- ing: dioctyl sodium sulfosuccinate 50 mg., and chdlic acid 100 mg. Index CATHARTICS (Bi) (68) BILE ACIDS AND SALTS (Bl) (68) SURFACE-ACTIVE AGENTS (JH) C68^ Aquedux see 4-chloro-m-benzenedisulfonamide aquocobalamin see HYDROXOCOBALAMIN 1-^-D-arabinofuranosylcytosine Reg. 147944 Index CYTARABINE (68) ARACHIDONIC ACID (Dll) (68) 5,8,11,14-eicosatetraenoic acid (CH3(CH2)4CH=(CHCH2CH=)3CH(CH2)3C00H); one of the polyunsaturated fats which apparently is not synthesized by the body and must be supplied by the diet. aralen see CHL0R0QUINE aramine bitartrate see \-(1-aminoethyl)-m-hydroxybenzyl alcohol arbide A cathartic preparation of protopectin and bark of Rhamnus frangula. Index CATHARTICS (68) arcofac A hypocholesteremic preparation containing vitamin B6 and safflower oil as active ingred- ients with tocopherols, propyl gallate, citric acid and sodium benzoate added. Index ANTICHOLESTEREMIC AGENTS (Bl)(68} PYRIDOXBJE (Bl) (68) FATTY ACIDS, ESSENTIAL (Bl) (68) arcosal see TOLBUTAMIDE arcton 63 see l,l,2-trichloro-l,2,2-tri- fluoroethane arctuvan An antiseptic preparation used in infections of the urinary and respiratory tracts. Index ANTI-INFECTIVE AGENTS, LOCAL (68) aramite see 2-(p-tert-butylphenoxy)-l- methylethyl 2-chloroethyl sulfite Arbid Reg. A combination preparation con- taining: nylidrin, ascorbic acid, rutin, aminpyrine and diphenyl- ■• pyraline. It is used in the treatment of the common cold. Index PHENETHYLAMINES (IM) (68) ASCORBIC ACID (Bl) (68) RUTIN (Bl) (68) AMINOPYRINE (IM (68) PIPERIDINES (Bl) (68) ardesyl see vitamin U arecaidine see 1,2,5,6-tetrahydromethyl nicotinic acid arecaine see 1,2,5,6-tetrahydromethyl nicotinic acid Arechin see chloroquine diphosphate 58 arfonad see TRIMETHAPHAN argicillin see hydroxymethylgramicidin arginine vasopressin A vasopressin isolated from bovine pituitary glands and containing arginine as one of the constituent amino acids instead of lysine as in the vasopressin isolated from hog pituitary glands. Index VASOPRESSIN (68) Aristamid see SULFISOMIDINE aristocillin A penicillin-sulfisomidine prep. Index PENICILLIN (Bl) (68) SULFISOMIDINE (Bl) (68) aristocort see TRIAMCINOLONE aristogyn A combination of sulfadimetine with carboxymethylcellulose. Index SULFISOMIDINE (IM) (68) METHYLCELLULOSE (Bl) (68) aristolochic acid A phenanthrene derivative isolated from the plant Aristolochia clematitis. Index PKENANTHRENES (68) o <*.«>* nox 1 i 1 Arlef see fiufenamic acid Arlidin see l-(p-hydroxyphenyl)-2-(l methyl-3-phenylpropyIamino) propanol armazal see cyanacetic acid hydrazide armil see cetyldimethylbenzylammonium chloride armin A preparation containing compound ethers of alkyl phosphinic acids with anticholinesterase action; used in the therapy of glaucoma. Index CHOLINESTERASE INHIBITORS (IM) (68) PHOSPHINIC ACIDS (Bl) (68) Arobon • see carob flour arovit see vitamin A Arpenal see N-(3-diethylaminopropyl)- 2,2-diphenylacetamide arsobal Syn. Mel B. An arsenical. Index ARSENICALS (68) ARSPHENAMINE (D3) (60) Reg. 150447 Syn. 606; arsaminol; arsenobenzene; 3,3'-diamino-4,4'-dihydroxyarseno- benzene dihydrochloride; Salvarsan; Sanluol. The oldest antisyphilitic arsenical. 59 artabasine Reg. A pharmacologically active principle from Artemisia absinthium. Index TERPENES (IM) (68) LACTONES (Bl) (68) SO HO CH, J )~a,i artrazone A TBj^ preparation containing N- dimethylaminoethy1-N'-p-chloro- benzyl-a-aminopyridine, phenyl- dime thylpyrazolonemethyIamino- sodium methanesulfonate, vitamin C and methionine. Used in rheumatism therapy. Index PYRB)INES (IM) PYRAZOLES (Bl) SULFONIC ACIDS (Bl) ASCORBIC ACID (Bl) METHIONINE (Bl) (68) (68) (68) (68) (68) artemisetin see 5-hydroxy-3,6,7,3',4'-penta- me thoxy flavone arteparon Index MUCOPOLYSACCHARIDES (68) artesan A 55 A preparation of acetylsalicylic acid, acetophenetidin, para- aminobenzoic acid and salicylamide, Index ASPIRIN (IM) (68) PHENACETIN (Bl) (68) AMINOBENZOIC ACID (Bl) (68) SALICYLAMIDES (Bl) (68) arylamidase Index AMIDOHYDROLASES (67) aryl-formylamine amidohydrolase see formamidase asahydrin see CHLORMERODRIN asarone A tranquilizing principle obtained from the volatile oil of Acorus calamus. Index TRANQUILIZING AGENTS (68) arthripax A dihydroxyaluminum glycinate- mephensin-salicylamide preparation, Index ALUMINUM (Bl) (68) MEPHENESIN (IM) (68) SALICYLAMIDES (Bl) (68) asbestos Index MINERALS (68) ascaroside A, B, C Glycoside components of ascarylic alcohol from Parascaris equorum. Index GLYCOSIDES (68) Arthrodestal • . . see 2-(dimethylamino)-1-methyl- ethyl-2,2-diphenyl-2-ethoxyacetate artisone see 21-acetoxypregnenolone artosin see TOLBUTAMIDE ascarylic alcohol A liposoluble unsaponifiable substance from the egg membrane of Parascaris equorum containing hydroxyl groups and consisting of 3 glycosides ascaroside A, B and C, Empirical formula C 33, H 68, 0 4 Index GLYCOSIDES (68) 60 ascarylose A 3,6-didesoxy-aldohexose, the sugar component of, ascarosides. Index HEXOSES (68) CMC i CM a. I C-MOM CHI-, Bull Soc Chim Biol 40(2-3):315, 1958 asiatic acid The aglycone of asiatlcoside. Index PLANTS, MEDICINAL (Bl) (63) TERPENES (Bl) (68) HocHt ascensil see 2-amino-4-picoline ascorbigen A An indole-bound ascorbic acid, Index ASCORBIC ACID (68) asiatlcoside Reg. 1400277 Syn. madecassol A rhamnose glycoside of asiatic acid isolated from a plant source and used in the treatment of vaginitis. Index GLYCOSIDES (Bl) (68) TERPENES (Bl) (68) ascorbigen B Ascorbic acid not bound to an indole moiety. Index ASCORBIC ACID (68) Asilone pediatric granules Granules containing 100 mg. activated polymethylsiloxane per 1 g. in a sweetened absorbent base. Index SILICON (68) ascriptin An acetylsalicylic acid - magnesium aluminum hydroxide preparation. Used in the treatment of headache and arthritis. Index ASPIHIN (Bl) (68) MAGNESIUM (Bl) (68) ALUMINUM (Bl) (68) asgoviscum forte A combination preparation contain- ing mistletoe, Allium sativum, Crataegus oxyacantha and vitamin P. Index PLANT EXTRACTS prov. (NB1) (68) BIOFLAVONOIDS (IM) (68) asmacilline A preparation of go salts of riboflavin theophylline, lobel and calcium bromide asthma therapy. Index ASTHMA *drug RIBOFLAVINS THEOPHYLLINE LOBELINE QUININE CALCIUM asolectin A commercially available soy bean lecithin. Index LECITHINS (im) (68) SOY BEANS (NBi) (68) Id and silver pyrophosphate. p ine, quinine . Used in therapy (Bl) (63) (NBI) (68) (NBI) (68) (NBI) (68) (NBI) (68) (NBI) (68) 61 ASPARAGINASE (D9) (68) An amidohydrolase, catalyzing the reaction: ^.-asparagine + H20 - ^-aspartate + NH3; 1^-asparagine amidohydrolase. asperthee in A pigment found in Aspergillus '. nidulans. Index PIGMENTS (Bl) (68) ASPERGILLUS (NBI) (68) aspartate transcarbamylase Index TRANSFERASES (67) aspartic aminopherase see glutamic-aspartic transaminase aspartocin Reg. An antibiotic isolated from Streptomyces griseus var. spiralis, and from Streptomyces violaceus. Index ANTIBIOTICS (68) aspartokinase Reg. A transphosphorylase which catalyzes the phosphorylation of aspartate. Index PHOSPHOTRANSFERASES (Bl) (68) ASPARTIC ACID (l^Bl) (68) c* \\v~s? *; sodium bromide, caleium bromide and thymus extract. Index EPHEDRINE (Bl) (68) THIOCYANATES (Bl) (68) BROMIDES (Bl) (68) 62 sterolc see 6-(2-diethylaminoethoxy)-2- dimethylaminobenzothiazole di-HCl asthma-6 An anti-asthmatic drug containing ephedrine HC1, khellin, caffeine, senega extract, potassium sulfo- guaiacolate, potassium iodide, Grindel's tincture and sodium benzoate. Index ASTHMA *drug therapy (Bl)(68) EPHEDRINE (NIM)(68) KHELLIN (NBI) (68) CAFFEINE (tfIM)(68) POTASSIUM IODIDE (NBI) (68) PLANT EXTRACTS (NBI) (68) asthma-Becker A mixture of ephedrine, isopropyl- antipyrine, papaverine and scopolamine. Index EPHEDRINE (Bl) (68) ANTIPYRINE (Bl) (68) PAPAVERINE (Bl) (68) SCOPOLAMINE (Bl) (68) asthma-frenon There are several asthma-frenon preparations each containing a great variety of ingredients. (For individual preparations and their compositions see Gehex Codex) asthmocaine A posterior pituitasry hormone - procaine - theophylline preparation. Index PITUITARY HORMONES, POSTERIOR (IM) (68) PROCAINE (IM) (68) THEOPHYLLINE (IM) (68) asthmo-kranit A preparation containing lobeline, theophylline, papaverine, spasmo- lytic benzyl compounds, atropine, antihistaminics, ephedrinerhodanate, and molecular combinations of phenobarbital with antipyrine. Index appropriate disease *drug ther (IM) (68) ANTIHISTAMINICS (NBI) (68) LOBELINE (NIM) (68) THEOPHYLLINE (NIM) (68) PAPAVERINE (NIM) (68) ATROPINE (NBI)- (68) EPHEDRINE (NBI) (68) PHENOBARBITAL (NBI) (68) asthmon A preparation containing dihydrocodeine, phenobarbital, agaric acid, Belladonna alkaloids, ephedrine, caffeine, sodium salicylate, theophylline, amido- pyrine and calcium gluconate. Used in the prevention and therapy of asthma. Index ASTHMA *drug therapy (68) asthma-longoral A prolonged action dragee used in the therapy of asthma, containing atropine sulfate, theophylline, caffeine, ethylpapaverine, ephedrine KC1, diphenhydramine HC1 and aminopyrine. Index ASTHMA *drug therapy (IM) (68) ATROPINE (NBI) (68) CAFFEINE (NIM) (68) EPHEDRINE (NBI) (68) PAPAVERINE (NBI) (68) THEOPHYLLINE (NBI) (68) DIPHENHYDRAMINE I- (NBI) (68) AMINOPYRINE (NBI) (68) asthremedin Consists of denatured protein ingredients from cowpox vaccine lymph, used in therapy of allergies, asthma, etc. by self- regulation of parasympathetics. Index BIOLOGICAL PRODUCTS (Bl) (68) PROTEINS (!M) (68) astiban see sodium antimony-2,3-meso- dimercaptosuccinate 63 astracillin see potassium («-phenoxyethyl) penicillin astrafer see dextriferron astreptine see SULFANILAMIDE atenual A combination preparation contain- ing: meprobamate, pentaerythrityl tetranitrate, and phenobarbital. It is used for the prevention of anginal attacks. Index MEPROBAMATE (IM) (68) PHENOBARBITAL (LM) (68) PENTAERYTHRITOL TETRANITRATE (IM) (68) astrocid see SULFANILAMIDE astrocillin A combination of penicillin with sulfadimetine. Index PENICILLIN (Bl) (68) SULFISOMIDINE (Bl) (68) Astrophyllin see 7-(2,3-dihydroxypropyl) theophylline astrumal see potassium perchlorate asulfidine see SALICYLAZOSULFAPYRIDBJE atan see BENZENE HEXACHLORIDE atarax see HYDROXYZBJE ateroid Reg, A heparinoid extracted from the intestinal mucosa. Index HEPARINOID (68) Atheran see 16cc-chloro-3-methylestrone athrombon see ETHYL BISCOUMACETATE atofan (Sp) Syn. cinchophen Index CINCHOPHEN (68) atonyl see CARBACHOL atophanyl Reg. A mixture of cinchophen and sodium salicylate. Index CINCHOPHEN (Bl) (68) SODIUM SALICYLATE (IK) (63) ataraxoid A hydroxyzine-prednisolone preparation. Index HYDROXYZBJE (Bl) (68) PREDNISOLONE (Bl) (68) atebrin see QUBJACRINE atosil see 10-(2-dimethylamino-2-methyl- ethyl)-phenothiazine ATP:creatine phosphotransferase see CREATINE KBJASE 64 ATP: glutamine synthetase adenylyl- transferase Reg. An enzyme contained in Escherichia coli which catalyzes covalent attachment of the adenylyl moiety of ATP to glutamine synthetase I. Index NUCLEOTH)YLTRNASFERASES (Bl) (68) LIGASES (Bl) (68) atriphos see ADENINE TRIPHOSPHATE atrocaine A combination of atropine with procaine with diuretic effects. Index ATROPINE (Bl) (68) PROCAINE (XM) (68) DIURETICS (Bl) (68) ATP:L-methionine-S-adenosyltransferase see methionine-activating enzyme atrolactamide see 2-hydroxy-2-phenylpropionamide ATP:pyruvate phosphotransferase see PYRUVATE KINASE atractylic acid Reg. A poisonous glycoside from Atractylis gummifer. Index GLYCOSIDES (68) Atromid see ethyl •*-(p-chlorophenoxy)- isobutyrate Atromid-S see ethyl «*--(p-chlorophenoxy)- isobutyrate atractyligenin Reg. A diterpenoid derivative which exerts an inhibitory action on oxidative phosphorylation without any uncoupling effect. Index TERPENES (68) ,^> Cc** atractyloside Reg. Index GLYCOSIDES ANTIMETABOLITES (Bl) (68) (Bl) (68) atrasine Reg. A herbicide which influences amino acid metabolism of soil bacteria. Index HERBICIDES (68) atrovenetin Reg. Syn. desoxynorherqueinone. A pigment from Penicillium atrovenetum; closely related to herqueinone and norherqueinone; a hydroxyperinaphthenone; empirical formula C 19, H 18, 0 6. Index PIGMENTS (68) A.T.S. A term used in the French litera- ture for trichloracetic acid and sulfosalicylic acid. Index TRICHLOROACETIC ACID (Bl) (68) SALICYLIC ACID (Bl) (68) SULFONIC ACIDS (Bl) (68) 65 attapulgite A mixture of aluminum silicate and magnesium silicate. Index ALUMINUM SILICATES )(B1) (68) MAGNESIUM (IM) (68) SILICATES (Bl) (68) Atumin see 2-diethylaminoethyl bicyclo- hexyl -1-carboxyla.te aturban see 3-(2-diethylaminoethyl)-3- phenyIglutarimide Aturgyl see 2-isopropyl-2-phenoxymethyl- imidazoline aurantins (D3) Provisional Antibiotics from the actinomycin group, isolated from Actinomyces aurantiacus. Aurantin is active against some gram-positive bacteria and against certain experimental cancers. Index ANTIBIOTICS, ANTINEOPLASTIC (68) aurantiogliocladin see 2,2-dimethoxy-5,6-dimethyl- benzoquinone aureofungin A new heptaene antibiotic produced by Streptomyces cinnamomeus Bene- dict var terricol, Thirum. Index ANTIBIOTICS (68) Atussil see 2-(2-diethylaminoethoxy)- ethyl-1-phenylcyclopentyl-l- carboxylate aureomykoin see CHLORTETRACYCLINE Au-Bi-01 suppository A preparation containing gold sodium dithiosulfate, bismuth . camphorcarbonate and aminppyrine. Index GOLD (Bl) (68) THIOSULFATES (IM) (68) BISMUTH ' (Bl) (68) AMINOPYRINE (Bl) (68) aureoquin see 4-(2-dimethylaminoethylamino) 6-methoxyquinoline diethylamino- tetrahydrophthalate auricillin C 305 see monacillin Auracet ear drops A preparation containing aluminum acetotartrate, lead subacetate, polyvinyl pyrroli- done and peppermint water. Index ALUMINUM (Bl) (68) LEAD (IM) (68) POLYVINYLPYRROLIDONE (Bi) (68) aurimbol A combined drug used in the local therapy of rheumatic conditions. Its active ingredients are gold and quinoline. It contains auro- isoquinoline-indole-dihydropyridine- hydroxydekalinecarboxylic acid methyl ester, procaine, honey, formaldehyde and formic acid. Index GOLD (Bi) (68) QUINOLINES (Bl) (68) 66 Auroi ..x APF or animal protein factor. A rermentation product of Streptomyces aureofaciens and a by-product of the manufacture of aureomycin. Contains at least tour factors in each 250 mg. cap- sule. APF, aureomycin 6.7mg, vitamin B 12a 1 microgram, vitamin 3 I2b 1 microgram and and unknown factor. Index VITAMIN B 12 (IM) (68) CHLORTETRACYCLINE (BO (68) aurovertin Reg. .An antibiotic which inhibits oxidative phosphorylation. Index ANTIBIOTICS ' (Bl) (68) ANTIMETABOLITES (Bl) (68) auxinutril see 2,2-bis-hydroxymethyl-l,3- propanediol avacalm A promoxolane-reserpine preparation. Index ETHERS, CYCLIC (Bl) (68) RESERPBJE (Bl) (68) avagal see METHANTHELINE avalon A chlorobutanol-salicylic acid preparation used in the therapy of skin mycosis. Index CHL0R0BUTAN0L (Bl) (68) SALICYLIC ACID . (Bi) (68) avapena see 2- p-chlorobenzyl-(2-dimethyl- aminoethyl)amino pyridine __ AVC see allantomide aveeno ointment Reg. 70304 An improved Lassar's paste preparation. Index HEXACHLOROPHENE (68) avenacin Reg. A fungicide isolated from oat roots. Chemically it is a tri- terpenoidal saponin having a carbohydrate chain of 3 units and an aromatic acid bound to the triterpene. Index ANTIFUNGAL AGENTS (Bl) (68) SAPONINS (Bl) (68) Aventyl see NORTRIPTYLINE avidin Reg. 1405692 A highly purified protein from egg white which specifically binds biotin and inhibits fatty acid synthesis. Index PROTEINS. (68) avlosulfone see DAPSONE avomine see 8-chloropheophyllinate-10- (2-dimethylaminopropyl)phenothia zine axeen see 5-allyl-5-(hydroxypropyl)- barbituric acid ___. axiquel see valmethamide ¥ Axiten see MEBUTAMATE 67 ayamycin * An antibiotic isolated from the culture filtrate of Streptomyces strain 0-80. Index ANTIBIOTICS (68) AZASERINE (D3,D4) 1963 Reg. 115026 Syn. o-diazoacetyl-L-serine An antineoplastic antibiotic from Streptomyces strains. AYF see antiyeast factor iJ C d.C ooc^^tnAr O l-O Coo ,4 8-azaadenine see 7-amino-v-triazolo£4,5-dJ pyrimidine azacon see PROTHIPENDYL azacytidine Index NUCLEOSIDES (68) AZAGUANINE (D2, D4) (63) Reg. 134587 Syn. 5-amino-l,6-dihydro-7H-2- triazolo [4,5-d3pyrimidin-7-one; azan. A purine derivative with antimeta- bolite properties. \ H Hi. K Azalumazine Index THIAZINES (68) azan aee AZAGUANINE 4-(3-azaspiro 5,5 undec-3-yl)-4'- fluorobutyrophenone Reg. Syn. WY-3457. A butyrophenone capable of reducing hallucinations in schizophrenics; the marked psycho-active effects warrants it classification as an " antidepressive agent. Index ANTIDEPRESSIVE AGENTS (Bl) (6 BUTYROPHENONES (Bl) (6 (30^^2.c^xcH3^ AZATHIOPRINE (D4) 1965 Reg. 446866 Syn. NSC-39084; BW-57-322; Imuran; 6-(l-methyl-4-nitroimidazol-5- ylthio)-purine. A drug used to suppress the immune reaction to tissue transplantation. ^J- azapetine see 6-allyl-6,7-dihydro-5H- dibenz Vc, e3 azepine azapiperonium see methyl-bis(^-N'-methyl- piper idiniumethyl) amine dibromide azauracil (D2) provisional Reg. Syn. 6-azauracil; as-triazine- 3,5(2H,4H)-dione. Index TRIAZINES (68) ii '/ 0 o 68 6-azauracil see azauracil 6-azauracil riboside see 6-azauridine 6-azauridine Reg. 54251 Syn. 6-azauracil riboside. Index TRIAZINES (68) azetidine-2-carboxylic acid Reg. 2517046 A cyclic amino: acid found in plants. Index AMINO ACIDS (68) Q-c-ooH azimethylene see DIAZOMETHANE azepinamide see l-(p-chlorophenylsulfonyl) 3-^iexahydro-l-azepinyl) -urea azeTEPA (D3) provisional Reg. 125451 Syn. P,P-bis-(l-aziridinyl)-N- ethyl-N-(l,3,4-thiadiazol-2-yl)- phosphinic amide. An alkylating agent, under in- vestigation in therapy of breast cancer. Index ALKYLATING AGENTS PHOSPHINIC ACIDS AZIRINES ES r 1 (IM) (68) (IM) (68) (IM) (68) ,v—*J 1 i azethion see 0,0-diethyl-S-methylcarboxy- « rnethylene-dithiophosphate aziridines A series of compounds based on aziridine. Are also called ethylenimines. Index AZIRBJES (68) Uil-CUjC^ °r R-N^2.^^ AZIRBJES (D2) 1968 A series of heterocyclic compounds with the structure # He. ^>c,S Includes aziridines(hydrogenated) ; also multi-ring heterocycles having an azirine or aziridine ring. azoangin see 2,4-diaminoazobenzene citrate EC1 azobenzeme see azobenzene azobenzene Reg. 103333 Syn. azobenzeme Index AZO COMPOUNDS (68) O-'-O 69 AZOCINES (D2) 1965 CH=CH-CH=CH-CH=CH-CH=N 1___________1 azohel see 2,4-diaminoazobenzene citrate HCl azoiprite see MECHLORETHAMINE azojod see 2,4-diaminoazobenzene citrate HCl azotase see nitrogenase azotox see DDT azotrex A phenylazo-diamino-pyridine - sulfamethizole - tetracycline preparation. Syn. uropol. Index PYRIDINES (Bl) (6S; TETRACYCLINE (Bl) (68) SULFATHIAZOLES (Bl) (68) azo-kur-salbe see 2,4-diaminoazobenzene citrate HCl Azoman see 4-cyclohexyl-3-ethyl-4H-l,2,4- triazole Azozol see 4-cyclohexyl-3-ethyl-4H- 1,2,4-triazole azulene see cyclopentacyclppentane azorhodan see chrysoidine monothiocyanate azulfadine see SALICYLAZOSULFAPYRIDINE azorhodanide H see chrysoidine monothiocyanate Azoseptyl T Reg. Index SULFONAMIDES (68) o LU; j azosulfamide see disodium 2-(4'-sulfamylphenyl- azo)-7-acetamido-l-hydroxynaphthal- ene-3,6-disulfonate azulone see l,4-dimethyl-7-isopropyl- azulene azure A carbacrylic resin see azuresin azuresin Reg. Syn. azure A carbacrylic resin; diagnex blue. An ion exchange resin used in the tubeless analysis of gastric acidity. Index ION EXCHANGE RESINS (63) I /