
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Letter from D. Carleton Gajdusek, The Children&apos;s Hospital (Cincinnati, Ohio) to Michael Heidelberger</dc:title>
  <dc:subject>Complement System Proteins</dc:subject>
  <dc:subject>Serology</dc:subject>
  <dc:description>Gajdusek here discussed experimental and clinical approaches to studying the connection between disease, in particular nephritis, and the level of complement in sera.  Gajdusek hypothesized that complement levels declined with the onset of disease, and rose again during recovery.  Complement is a complex system of over twenty serum proteins that play an essential enzymatic role in host defense mechanisms against invading organisms.</dc:description>
  <dc:publisher>Produced: 28 February 1948</dc:publisher>
  <dc:contributor>Children&apos;s Hospital (Cincinnati, Ohio)</dc:contributor>
  <dc:contributor>The Children&apos;s Hospital (Cincinnati, Ohio)</dc:contributor>
  <dc:contributor>Gajdusek, D. Carleton</dc:contributor>
  <dc:contributor>Gajdusek, D. Carleton</dc:contributor>
  <dc:type>Letters (correspondence)</dc:type>
  <dc:format>Archival Materials</dc:format>
  <dc:format>Text</dc:format>
  <dc:format>2 pages</dc:format>
  <dc:identifier>nlm:nlmuid-101584940X96-doc</dc:identifier>
  <dc:identifier>101584940X96</dc:identifier>
  <dc:identifier>http://resource.nlm.nih.gov/101584940X96</dc:identifier>
  <dc:identifier>Profiles ID: DHBBGQ</dc:identifier>
  <dc:language>English</dc:language>
  <dc:relation>Profiles in Science</dc:relation>
</oai_dc:dc>