Some Relationships of Structure to Function in Ribonuclease Ribonucleases Oxidation-Reduction Protein Conformation Disulfides This study by White and Anfinsen on the renaturation of fully denatured ribonuclease, or RNase, required subsequent supporting investigations to establish what came to be called the "thermodynamic hypothesis." Here they reported that RNase activity depended upon a variety of structural features, but noted that it could be inferred from the results of their experimentation that only a small part of the enzyme molecule, what they termed the "active center," was necessary for catalyst. New York Academy of Sciences, 4 September 1959 The New York Academy of Sciences, 4 September 1959 Annals of the New York Academy of Sciences White, F. H., Jr Anfinsen, Christian B. Anfinsen, Christian B. Articles Archival Materials Text 9 pages nlm:nlmuid-101584571X166-doc 101584571X166 http://resource.nlm.nih.gov/101584571X166 Profiles ID: KKBBKY English Profiles in Science