Alirocumab for treatment of high cholesterol: effectiveness and value : new evidence update

Alirocumab for treatment of high cholesterol: effectiveness and value : new evidence update

Collection:
Health Policy and Services Research
Author(s):
Tice, Jeffrey A., author
Chapman, Rick M., author
Rind, David M., author
Pearson, Steven D., author
Kazi, Dhruv S., author
Coxson, Pamela G., author
Penko, Joanne, author
Bibbins-Domingo, Kristen, author
Contributor(s):
Institute for Clinical and Economic Review, issuing body.
Publication:
[Boston, Massachusetts] : Institute for Clinical and Economic Review, February 15, 2019
Language(s):
English
Format:
Text
Subject(s):
Hypercholesterolemia -- drug therapy
Proprotein Convertase 9
United States
Genre(s):
Technical Report
Abstract:
ICER’s New Evidence Update for alirocumab (Praluent®, Regeneron/Sanofi) is based on results from the ODYSSEY outcomes trial published in the New England Journal of Medicine on November 7, 2018. We used the results published in the manuscript to update our preliminary cost-effectiveness analyses and associated value-based price benchmarks for this drug. ICER’s value-based price benchmarks suggest a price range that would align fairly with the added benefits of new treatment options for patients and the health care system. ICER previously assessed the cost-effectiveness of alirocumab and evolocumab (Repatha®, Amgen Inc.) shortly after these drugs were first granted regulatory approval in the United States in 2015, and performed a New Evidence Update for evolocumab in September 2017 following the release of outcomes data from the FOURIER trial. A preliminary new evidence update for alirocumab was published on March 10, 2018, following presentation of the results at the American College of Cardiology’s 2018 Scientific Session.
Copyright:
Reproduced with permission of the copyright holder. Further use of the material is subject to CC BY license. (More information)
Extent:
1 online resource (1 PDF file (12 pages))
Illustrations:
Illustrations
NLM Unique ID:
9918401083006676 (See catalog record)
Permanent Link:
http://resource.nlm.nih.gov/9918401083006676