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Letter from Michael Heidelberger to A. M. Pappenheimer, Jr., University of Pennsylvania School of Medicine
Letter from Michael Heidelberger to A. M. Pappenheimer, Jr., University of Pennsylvania School of Medicine
Contributor(s):
Heidelberger, Michael Pappenheimer, A. M. (Alwin Max), 1908-1995 University of Pennsylvania. School of Medicine
In this exchange of letters Heidelberger and Pappenheimer discussed hypotheses and evidence regarding the location of the sites at which antibody molecules (later shown to be Y-shaped) bind to antigens. One hypothesis, proposed by the preeminent physical chemist Linus Pauling and discussed in this letter, held that these binding sites were located at the ends of a symmetrical molecule.
Copyright:
The National Library of Medicine believes this item to be in the public domain. (More information)