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Low-Dose Captopril for the Treatment of Mild to Moderate Hypertension
Low-Dose Captopril for the Treatment of Mild to Moderate Hypertension
Contributor(s):
Hypertension Veterans Administration Cooperative Study Group on Antihypertensive Agents
Publication:
American Heart Association, [September-October 1983]
In this article, the Veterans Administration Cooperative Study Group reported on their double-blind trial involving the new antihypertensive agent, captopril, an angiotensin converting enzyme (ACE) inhibitor. Like all ACEs, captopril prevents the synthesis of angiotensin II, a hormone that usually causes blood vessels to constrict. Although acknowledging the need for further study, the group determined that captopril appeared to be a very effective antihypertensive agent, especially when administered in combination with the diuretic hydrochlorothiazide.
Copyright:
The National Library of Medicine believes this item to be in the public domain. (More information)