Evaluation of Toxicity in Long-Term Clinical Trials

Evaluation of Toxicity in Long-Term Clinical Trials

Contributor(s):
Journal of the American Medical Association
Freis, Edward D.
Publication:
American Medical Association, 1 February 1964
Language(s):
English
Format:
Text
Subject(s):
Hypertension
Antihypertensive Agents
Drug-Related Side Effects and Adverse Reactions
Clinical Trials as Topic
Genre(s):
Archival Materials
Articles
Abstract:
Along with being a pioneer in hypertension treatment, Freis was a pioneer in the evolution of controlled double-blind clinical trials. In this article, he argued that patients in clinical trials must be protected from hazards by prior trials in animals and acute trials in patients, as well as effective design, careful observation, and prompt reporting of toxicity.
Copyright:
The National Library of Medicine believes this item to be in the public domain. (More information)
Extent:
4 pages
NLM Unique ID:
101584929X82 (See in Profiles in Science)
Profiles in Science ID:
XFBBFY
Permanent Link:
http://resource.nlm.nih.gov/101584929X82
Archival Collection:
The Edward D. Freis Papers (Profiles in Science)