Evaluation of Toxicity in Long-Term Clinical Trials
- Contributor(s):
- Journal of the American Medical Association Freis, Edward D.
- Publication:
- American Medical Association, 1 February 1964
- Language(s):
- English
- Format:
- Text
- Subject(s):
- Hypertension Antihypertensive Agents Drug-Related Side Effects and Adverse Reactions Clinical Trials as Topic
- Genre(s):
- Archival Materials Articles
- Abstract:
- Along with being a pioneer in hypertension treatment, Freis was a pioneer in the evolution of controlled double-blind clinical trials. In this article, he argued that patients in clinical trials must be protected from hazards by prior trials in animals and acute trials in patients, as well as effective design, careful observation, and prompt reporting of toxicity.
- Copyright:
- The National Library of Medicine believes this item to be in the public domain. (More information)
- Extent:
- 4 pages
- NLM Unique ID:
- 101584929X82 (See in Profiles in Science)
- Profiles in Science ID:
- XFBBFY
- Permanent Link:
- http://resource.nlm.nih.gov/101584929X82
- Archival Collection:
- The Edward D. Freis Papers (Profiles in Science)