Clinical Trial of Guanethidine, a New Type of Antihypertensive Agent

Clinical Trial of Guanethidine, a New Type of Antihypertensive Agent

Contributor(s):
The Medical Annals of the District of Columbia
Frohlich, Edward D.
Freis, Edward D.
Publication:
Medical Society of the District of Columbia, August 1959
Language(s):
English
Format:
Text
Subject(s):
Hypertension
Antihypertensive Agents
Guanethidine
Genre(s):
Archival Materials
Articles
Abstract:
Throughout the 1950s and 1960s several ganglionic-blocking agents were introduced that provided a variety of options for clinicians treating high blood pressure. These agents reduced blood pressure by interfering with nerve impulses from the brain that constricted blood vessels. In this article, Freis and Frohlich reported that one of these agents, guanethidine, exhibited a potent, orthostatic, antihypertensive effect similar to other ganglionic-blocking agents.
Copyright:
The National Library of Medicine believes this item to be in the public domain. (More information)
Extent:
4 pages
NLM Unique ID:
101584929X49 (See in Profiles in Science)
Profiles in Science ID:
XFBBDJ
Permanent Link:
http://resource.nlm.nih.gov/101584929X49
Archival Collection:
The Edward D. Freis Papers (Profiles in Science)