Treatment of Essential Hypertension with Chlorothiazide (Diuril): Its Use Alone and Combined with Other Antihypertensive Agents

Treatment of Essential Hypertension with Chlorothiazide (Diuril): Its Use Alone and Combined with Other Antihypertensive Agents

Contributor(s):
Journal of the American Medical Association
Wanko, Annemarie
Wilson, Ilse M.
Parrish, Alvin E.
Freis, Edward D.
Publication:
American Medical Association, 11 January 1958
Language(s):
English
Format:
Text
Subject(s):
Hypertension
Antihypertensive Agents
Chlorothiazide
Genre(s):
Archival Materials
Articles
Abstract:
In this article, Freis and his colleagues reported the results of their initial trials of the new diuretic, chlorothiazide, in patients with moderate hypertension. Chlorothiazide often reduced blood pressure when used alone; when used together with other antihypertensive drugs, it potentiated their effects, so that lower doses of the other drugs could be used, and side-effects could be avoided. Chlorothiazide represented a major advance in the treatment of hypertension.
Copyright:
The National Library of Medicine believes this item to be in the public domain. (More information)
Extent:
4 pages
NLM Unique ID:
101584929X135 (See in Profiles in Science)
Profiles in Science ID:
XFBBJP
Permanent Link:
http://resource.nlm.nih.gov/101584929X135
Archival Collection:
The Edward D. Freis Papers (Profiles in Science)