Relationship Between Plasma and Extracellular Fluid Volume Depletion and the Antihypertensive Effect of Chlorothiazide

Relationship Between Plasma and Extracellular Fluid Volume Depletion and the Antihypertensive Effect of Chlorothiazide

Contributor(s):
Circulation
Wilson, Ilse M.
Freis, Edward D.
Publication:
American Heart Association, December 1959
Language(s):
English
Format:
Text
Subject(s):
Hypertension
Antihypertensive Agents
Chlorothiazide
Genre(s):
Archival Materials
Articles
Abstract:
Freis and Wilson collaborated on several papers on various treatments for hypertension in the 1950s. In this article, they discussed the effect of the diuretic chlorothiazide on extracellular fluid and plasma, noting that it significantly reduced both plasma volume and body weight during the first two to three days of treatment. They noted, however, that continued use resulted in no further reduction of extracellular fluid.
Copyright:
The National Library of Medicine believes this item to be in the public domain. (More information)
Extent:
9 pages
NLM Unique ID:
101584929X122 (See in Profiles in Science)
Profiles in Science ID:
XFBBHX
Permanent Link:
http://resource.nlm.nih.gov/101584929X122
Archival Collection:
The Edward D. Freis Papers (Profiles in Science)