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Oxprenolol vs Propranolol: A Randomized, Double-Blind, Multiclinic Trial in Hypertensive Patients Taking Hydrochlorothiazide
Oxprenolol vs Propranolol: A Randomized, Double-Blind, Multiclinic Trial in Hypertensive Patients Taking Hydrochlorothiazide
Contributor(s):
Hypertension Veterans Administration Cooperative Study Group on Antihypertensive Agents
In this article, Freis's team compared oxprenolol and propranolol, both beta-adrenergic blocking agents, in mild and moderate hypertension patients who had not responded well to the diuretic hydrochlorothiazide. They found that after six months a significant reduction in blood pressure occurred in half of the patients that took propranolol along with the diuretic, whereas only twenty-seven percent of the patients that took oxprenolol with a diuretic achieved similar results.
Copyright:
The National Library of Medicine believes this item to be in the public domain. (More information)