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Monoclonal Antibody to a Plasma Membrane Antigen of Neurons
Monoclonal Antibody to a Plasma Membrane Antigen of Neurons
Contributor(s):
Eisenbarth, George S. Nirenberg, Marshall W. Walsh, Frank (Frank S.), 1953- Proceedings of the National Academy of Sciences of the United States of America
In the late 1970s and early 1980s, the biochemical lab at NIH undertook a series of studies with clonal and hybrid cell lines that produced antibody, which bound to certain neural tissues but not others. This article discusses a hybrid cell line that synthesizes an antibody, suggesting the need for studies of the synthesis, localization, and function of that antigen.
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