Synapse Turnover: A Mechanism for Acquiring Synaptic Specificity

Synapse Turnover: A Mechanism for Acquiring Synaptic Specificity

Contributor(s):
Thompson, Jeffrey M.
Eisenbarth, George S.
Ruffolo, Robert R.
Nirenberg, Marshall W.
Proceedings of the National Academy of Sciences of the United States of America
Publication:
National Academy of Sciences (U.S.), May 1978
Language(s):
English
Format:
Text
Subject(s):
Neuromuscular Junction
Synapses
Genre(s):
Archival Materials
Articles
Abstract:
In previous studies on synapse formation, "chick embryo retina neurons were shown to form synapses rapidly with striated muscle cells" but were transient and eventually disappeared. This report uses striated muscle cells to define the number of neurons that are able to form synapses at different stages of development and suggests that both correct and incorrect synapses are formed during normal embryonic development, with correctly matched synapses being retained.
Copyright:
This item may be under copyright protection; contact the copyright owner for permission before re-use.
Extent:
5 pages
NLM Unique ID:
101584910X65 (See in Profiles in Science)
Profiles in Science ID:
JJBBFC
Permanent Link:
http://resource.nlm.nih.gov/101584910X65
Archival Collection:
The Marshall W. Nirenberg Papers (Profiles in Science)