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Receptor-Mediated Shifts in cGMP and cAMP Levels in Neuroblastoma Cells
Receptor-Mediated Shifts in cGMP and cAMP Levels in Neuroblastoma Cells
Contributor(s):
Nirenberg, Marshall W. Matsuzawa, Hiroshi Proceedings of the National Academy of Sciences of the United States of America
Publication:
National Academy of Sciences (U.S.), September 1975
Nirenberg's interest in neuroblastoma research defined his work by the early 1970s. In this article, neuroblastoma cells are used to examine the various responses of neurons to neurotransmitters based on differences in tissue and cell type. The experimental strategy is to use the relatively homogeneous clonal neuroblasts, which have excitable membranes and respond well to chemical and electrical stimuli, to define receptor mediated responses more clearly.
Copyright:
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