Characteristics and Stabilization of DNAase-Sensitive Protein Synthesis in E. Coli Extracts

Characteristics and Stabilization of DNAase-Sensitive Protein Synthesis in E. Coli Extracts

Contributor(s):
Nirenberg, Marshall W.
Matthaei, Heinrich
Proceedings of the National Academy of Sciences of the United States of America
Publication:
National Academy of Sciences (U.S.), October 1961
Language(s):
English
Format:
Text
Subject(s):
Escherichia coli
Deoxyribonucleases
Genre(s):
Archival Materials
Articles
Abstract:
This innovative article is one of Nirenberg's most important early contributions to the coding problem. Published along with "The Dependence of Cell-Free Protein Synthesis in E. coli Upon Naturally Occurring or Synthetic Polyribonucleotides," this article provides experimental evidence that an extract prepared from bacterial cells can make protein even when intact living cells are not present. This revelation is a crucial step in the history of breaking the genetic code.
Copyright:
This item may be under copyright protection; contact the copyright owner for permission before re-use.
Extent:
9 pages
NLM Unique ID:
101584910X49 (See in Profiles in Science)
Profiles in Science ID:
JJBBDJ
Permanent Link:
http://resource.nlm.nih.gov/101584910X49
Archival Collection:
The Marshall W. Nirenberg Papers (Profiles in Science)