Laboratory project: "Studies of Action Potential and Receptor Ionophores"

Laboratory project: "Studies of Action Potential and Receptor Ionophores"

Contributor(s):
Ray, Radharaman
National Heart and Lung Institute. Laboratory of Biochemical Genetics
Huang, L. M.
Catterall, W. A.
Publication:
Produced: September 1976
Language(s):
English
Format:
Text
Genre(s):
Archival Materials
Reports
Excerpts
Abstract:
Summary of work for this project as indicated on the report: "The objective of this project is to develop biochemical methods for studies of action potential and receptor ionophores leading eventually to isolation of these macromolecules and characterization at both the molecular and cellular levels. Our current efforts are directed toward developing reagents, mainly neurotoxins, which act on the action potential Na+ ionophore, preparing radioactively labelled (sic) derivatives, and using these reagents to characterize the ionophore at the cellular level and to solubilize and eventually isolate it. The nicotinic acetylcholine receptor ionophore is also under study at the cellular level."
Copyright:
The National Library of Medicine believes this item to be in the public domain. (More information)
Extent:
3 pages
NLM Unique ID:
101584910X233 (See in Profiles in Science)
Profiles in Science ID:
JJBBPG
Permanent Link:
http://resource.nlm.nih.gov/101584910X233
Archival Collection:
The Marshall W. Nirenberg Papers (Profiles in Science)