Laboratory project: "Acetylcholine Receptors"

Laboratory project: "Acetylcholine Receptors"

Contributor(s):
Daniels, Mathew P.
Vogel, Zvi
Nirenberg, Marshall W.
National Heart and Lung Institute. Laboratory of Biochemical Genetics
Nelson, Phillip G.
Maloney, G.
Christian, Clifford
Publication:
Produced: September 1976
Language(s):
English
Format:
Text
Genre(s):
Archival Materials
Reports
Excerpts
Abstract:
Summary of work on this project as indicated on the report: "Our aim is to study the distribution of nicotinic acetylcholine receptors in intact and cultured tissues of the peripheral and central nervous system in relationship to the development and function of synapses. To this purpose histochemical localization of alpha-bungarotoxin bound to the receptors is used in conjunction with light and electron microscopy. In the past year we have studied the ultrastructural distribution of receptors on cultured skeletal muscle fibers and have initiated the following investigations: 1) location and characterization of synapses formed by neuroblastoma hybrid cells in culture 2) modification of histochemical methods in order to permit ultrastructural analysis of receptor distribution in the central nervous system and 3) analysis of the distribution of receptors in the visual system of the goldfish with relationship to optic nerve damage and regeneration."
Copyright:
The National Library of Medicine believes this item to be in the public domain. (More information)
Extent:
3 pages
NLM Unique ID:
101584910X228 (See in Profiles in Science)
Profiles in Science ID:
JJBBNZ
Permanent Link:
http://resource.nlm.nih.gov/101584910X228
Archival Collection:
The Marshall W. Nirenberg Papers (Profiles in Science)