Dual Regulation of Adenylate Cyclase by Endogenous Opiate Peptides

Dual Regulation of Adenylate Cyclase by Endogenous Opiate Peptides

Contributor(s):
Nirenberg, Marshall W.
Lampert, Arthur
Klee, Werner A.
Publication:
Elsevier/North-Holland Biomedical Press, 1976
Language(s):
English
Format:
Text
Subject(s):
Adenylyl Cyclases
Receptors, Opioid
Opioid Peptides
Genre(s):
Archival Materials
Monographs
Excerpts
Proceedings
Abstract:
This monograph expands on the relationship between morphine and other narcotics and the enzyme adenylate cyclase, arguing that endogenous opiate peptides act as dual regulators of adenylate cyclase exactly as morphine and other conventional narcotics. As potent, receptor mediated, inhibitors of adenylate cyclase activity in homogenates of hybrid cells, these peptides also have "addiction-like" qualities.
Copyright:
This item may be under copyright protection; contact the copyright owner for permission before re-use.
Extent:
4 pages
NLM Unique ID:
101584910X212 (See in Profiles in Science)
Profiles in Science ID:
JJBBND
Permanent Link:
http://resource.nlm.nih.gov/101584910X212
Archival Collection:
The Marshall W. Nirenberg Papers (Profiles in Science)