Synapse Selection Based on Differences in Synapse Turnover

Synapse Selection Based on Differences in Synapse Turnover

Contributor(s):
Thompson, Jeffrey M.
Eisenbarth, George S.
Ruffolo, Robert R.
Nirenberg, Marshall W.
International Journal of Developmental Neuroscience
Publication:
Pergamon Press, Inc., 1983
Language(s):
English
Format:
Text
Genre(s):
Archival Materials
Articles
Abstract:
As a continuation of Marshall Nirenberg's work in neurobiology in the early 1980s, the study in this article shows different degrees of synapse formation in neurons and muscle tissue cells. The experiment shows that "rat retinal neurons form transient synapses with rat muscle cells only during a discrete period in development, whereas chick embryo spinal cord neurons form synapses with rat muscle cells at all developmental stages tested." Findings suggest that different rates of turnover with synapses can result in the selective retention of one population of synapses and loss of the other.
Copyright:
This item may be under copyright protection; contact the copyright owner for permission before re-use.
Extent:
6 pages
NLM Unique ID:
101584910X167 (See in Profiles in Science)
Profiles in Science ID:
JJBBKZ
Permanent Link:
http://resource.nlm.nih.gov/101584910X167
Archival Collection:
The Marshall W. Nirenberg Papers (Profiles in Science)