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Synapse Formation by Neuroblastoma Hybrid Cells
Synapse Formation by Neuroblastoma Hybrid Cells
Contributor(s):
Fukui, H. Nirenberg, Marshall W. Ray, Radharaman Wilson, Steven P. Busis, N. Higashida, Haruhiro Krueger, K. Rotter, Andrej Adler, Michael Kenimer, James G. Molecular Neurobiology
This article maintains that both biological and environmental factors are important to consider in neural synaptic formation. Using the clonal line of neuroblastoma and somatic hybrid cells developed by Nirenberg and the biochemical genetics team at NIH, the experiment demonstrates that synaptogenesis can be influenced by the activation of the enzyme adenylate cyclase.
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