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Unpublished transcript of the Columbia University Symposium on the Relationship between Biological and Physical Sciences
Unpublished transcript of the Columbia University Symposium on the Relationship between Biological and Physical Sciences
Professors Devons and Rabi provide introductions to Nirenberg's speech. Rabi jokes that Nirenberg's "translation" efforts sound more like physics or linguistics than biology, and on that note Nirenberg emphasizes the collaborative nature of the project. The determination of the sequence of triplets allowed Nirenberg and others to synthesize 63 of the 64 possible triplets by the time of the symposium. According to Nirenberg, remaining problems included an explanation for why the code looks like it does, an answer to the question of meaning within the code, and a precise explanation for the relationship between differences in codons and biological roles.
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