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The Behavior in Successive Nuclear Divisions of a Chromosome Broken at Meiosis
The Behavior in Successive Nuclear Divisions of a Chromosome Broken at Meiosis
Contributor(s):
McClintock, Barbara, 1902-1992 Proceedings of the National Academy of Sciences of the United States of America
After reporting her observations of ring chromosomes, McClintock followed broken chromatids through successive cycles of cell division, in which she could observe the behavior of the "monstrous" chromosome 9 through meiosis and crossing-over. McClintock reported in a long series of articles that the chromatid breakage-fusion-bridge (BFB) cycle occurred only in the germ cells and endosperm, while the chromosome BFB continued in the sporophyte, which meant that she could selectively produce persistent variegation in plant tissues.
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