Ultraviolet Irradiation of Bacteriophage during Intracellular Growth

Ultraviolet Irradiation of Bacteriophage during Intracellular Growth

Contributor(s):
Journal of Bacteriology
Luria, S. E. (Salvador Edward), 1912-1991
Latarjet, Raymond, 1911-
Publication:
American Society for Microbiology, February 1947
Language(s):
English
Format:
Text
Subject(s):
Bacteriophages
Mutagenesis
Genre(s):
Archival Materials
Articles
Abstract:
In this paper, Luria and Latarjet described a subpopulation of E. coli, strain B infected with bacteriophage T2, with increased resistance to UV. They indicated that the infected bacteria initially showed a rapid increase in resistance due to increased resistance of the intracellular phage particles, possibly caused by accumulation of ultraviolet-absorbing material around the phage. With time, the resistance of infected bacteria to high doses of radiation decreases, likely indicating that, as phage multiplication proceeds, the apparent sensitivity of the intracellular phage particles returns to higher values. Luria spent the 1945-1946 academic year on leave in Cold Spring Harbor, directing a government research project on bacterial resistance to antibiotics. The research produced several papers, including this one.
Copyright:
This item may be under copyright protection; contact the copyright owner for permission before re-use.
Extent:
15 pages
NLM Unique ID:
101584611X90 (See in Profiles in Science)
Profiles in Science ID:
QLBBGJ
Permanent Link:
http://resource.nlm.nih.gov/101584611X90
Archival Collection:
The Salvador E. Luria Papers (Profiles in Science)