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Letter from Salvador E. Luria to Arthur B. Pardee
Letter from Salvador E. Luria to Arthur B. Pardee
Contributor(s):
University of California, Berkeley Pardee, Arthur B. (Arthur Beck), 1921- Luria, S. E. (Salvador Edward), 1912-1991 American Philosophical Society. Library. Salvador Luria Papers
Here, Luria responds to an inquiry by Pardee, who--along with Francois Jacob and Jacque Monod--had just one year earlier shown that the enzyme beta-galactosidase is induced by changes in culture conditions. It was the first example of negative control of induction due to a repressor protein. This discovery set the stage for additional experiments that further delineated the interaction of a regulatory protein with a site on DNA that controls expression of other genes. With this letter, Luria also enclosed a copy of his 1949 article with Rene Dulbecco.
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