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Letter from Francis Crick to Aaron Klug
Letter from Francis Crick to Aaron Klug
Contributor(s):
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers Klug, Aaron Crick, Francis, 1916-2004
Crick here commented on results of Klug's X-ray crystallographic studies of chromatin, the assembly of DNA and proteins that form the genetic material on the chromosomes of higher organisms, and of nucleosomes. Nucleosomes are distinct complexes on the chromosomes of eukaryotic cells (cells with clearly-defined nuclei), and consist of eight histone molecules wrapped by a DNA segment of about 150 base pairs in length. Under the electron microscope nucleosomes, which are linked to each other by DNA sequences about fifty base pairs in length, appear as bead-like bodies on a string.
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