Letter from Francis Crick to Aaron Klug

Letter from Francis Crick to Aaron Klug

Contributor(s):
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Klug, Aaron
Crick, Francis, 1916-2004
Publication:
Produced: 30 June 1977
Language(s):
English
Format:
Text
Subject(s):
DNA
Nucleosomes
Crystallography, X-Ray
Genre(s):
Archival Materials
Letters (correspondence)
Abstract:
Crick here commented again on the draft of a paper by Klug on the spatial arrangement of DNA and histones (proteins associated with DNA) in nucleosomes, particularly on the dimensions of the DNA helix, whether the DNA helix was itself coiled in a nucleosome (forming a coiled coil, or superhelix), and the number of base pairs per turn of the superhelix. Crick also pointed out that as DNA shrank from its hydrated, elongated B form (or fiber form) to its shorter, drier A form, the X-ray diffraction patterns of DNA in nucleosomes changed in ways that might affect Klug's conclusions.
Copyright:
This item may be under copyright protection; contact the copyright owner for permission before re-use.
Extent:
2 pages
NLM Unique ID:
101584582X231 (See in Profiles in Science)
Profiles in Science ID:
SCBBQG
Permanent Link:
http://resource.nlm.nih.gov/101584582X231
Archival Collection:
The Francis Crick Papers (Profiles in Science)