Letter from Francis Crick to Sewell Champe

Letter from Francis Crick to Sewell Champe

Contributor(s):
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Crick, Francis, 1916-2004
Champe, Sewell
Publication:
Produced: 6 March 1967
Language(s):
English
Format:
Text
Subject(s):
Genetic Code
Genre(s):
Archival Materials
Letters (correspondence)
Abstract:
Crick here responded to Champe's report of results from his research with the rII mutants of the bacterial viruses T2 (phage) which had been used since the early 1950s in genetic mapping experiments. Crick himself discussed results of research with acridine mutants of bacteriophage T2, a different family of mutants in whose study Crick's laboratory specialized and which he used to provide evidence for the three-letter composition of the genetic code. The specific experiments to which Crick referred were with acridine mutants called amber (the triplet UAA) and ochre (UAG) and with the triplet UGA, all three of which signal the end of the polypeptide chain in protein synthesis.
Copyright:
This item may be under copyright protection; contact the copyright owner for permission before re-use.
Extent:
2 pages
NLM Unique ID:
101584582X206 (See in Profiles in Science)
Profiles in Science ID:
SCBBNZ
Permanent Link:
http://resource.nlm.nih.gov/101584582X206
Archival Collection:
The Francis Crick Papers (Profiles in Science)