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Letter from Sydney Brenner to Francis Crick
Letter from Sydney Brenner to Francis Crick
Contributor(s):
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers Crick, Francis, 1916-2004 Brenner, Sydney
Brenner here reported results from his research with mutations of the phages (bacterial viruses) T2 and T4, research designed to match a mutation in the fine structure of a phage gene to changes in a protein whose synthesis the virus triggered when it infected a bacterial cell. Brenner sought to give experimental support to Crick's sequence hypothesis: that the sequence of the bases in DNA specified the order of the amino acids in the polypeptide chain of proteins.
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