Antiblastic Immunity

Antiblastic Immunity

Contributor(s):
Avery, Oswald Theodore, 1877-1955
Dochez, A. R. (Alphonse Raymond)
Journal of Experimental Medicine
Publication:
Rockefeller University. Press, January 1916
Language(s):
English
Format:
Text
Genre(s):
Archival Materials
Articles
Abstract:
In this mildly controversial article, Dochez and Avery presented their theory of antiblastic immunity--the resistance to pneumococci as a result of the inhibition of particular pneumococcal enzymes by the serum from an infected person or animal--that promised to shed considerable light on the mechanisms by which parasitic bacteria establish themselves in animal tissue. Subsequent research conducted by others at the Rockefeller Institute determined that although antipneumococcal serum could retard the growth of pneumococci, it was not due to inhibition of enzymatic activity but the result of agglutination, which had few practical applications, effectively disproving Avery and Dochez's theory of antiblastic immunity.
Copyright:
The National Library of Medicine believes this item to be in the public domain. (More information)
Extent:
8 pages
NLM Unique ID:
101584575X529 (See in Profiles in Science)
Profiles in Science ID:
CCGMBJ
Permanent Link:
http://resource.nlm.nih.gov/101584575X529
Archival Collection:
The Oswald T. Avery Collection (Profiles in Science)