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Kinetics of Folding of Staphylococcal Nuclease
Kinetics of Folding of Staphylococcal Nuclease
Contributor(s):
Anfinsen, Christian B. (Christian Boehmer), 1916-1995 Schechter, Alan N. Science Chen, Raymond F.
Publication:
American Association for the Advancement of Science, 6 February 1970
In this article, Anfinsen, Schecter, and Chen reported one of the first direct measurements of the folding of proteins to their native conformation from a disordered state by use of a stopped-flow spectrofluorometer. Understanding protein folding was seen as an essential intermediate step to obtaining the information of the genetic code for the biological function of the corresponding protein or polypeptide chain.
Copyright:
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