This program will analyze the structure of
cartilage.
We will examine the microscopic and the light and
electron microscopic appearance of highland
cartilage,
fiber cartilage and elastic cartilage.
Detailed objectives may be found in the accompanying study
guide.
All cartilage is a vascular
and has a characteristic gel type
matrix Within the matrix
cells termed the contra sides
are located in cavity is called Laconi.
The three types of cartilage differ in the
amount and the type of connective tissue
elements embedded within the gel matrix.
Let's begin our study with highland
cartilage.
This is a macroscopic
slide of the human trachea.
On the Luminal side.
You can see the covering
apathy via underlying the
epithelium.
We can see the connective tissue.
The lighter staining mass
is the highland cartilage.
We will now examine this area under the low power
objective of the light microscope.
The Luminal side
has a covering of pseudo
stratified,
silly ated kilometer apathy Veum
with an underlying loose connective tissue
and the cartilaginous plaque
prepare Conry um
is a connective tissue layer that surrounds the
body of cartilage.
It has an inner Condra
genic layer,
an outer fibrous
layer.
The highland cartilage has a light stained appearance
with Condra sides
present with an
Laconi.
Yeah the cartilage cells
or Congress sites originate from the
surrounding layer of the american dream
Cartilage may grow by two
methods oppositional and
interstitial oppositional growth
refers to growth from the
outside
of a cartilage mass and originates from the
american dream
interstitial growth
is from the inside and it's
due to division and subsequent
secretion by the Congress,
sides
cartilaginous growth is most active throughout embryonic
life and only the potential for
growth of these cells
exists in the adult.
The newly formed cells secrete both highland
matrix and all fibrous
components.
New cells tend to surround
themselves and isolate
themselves within a Laconi.
The sales may continue to divide and
subsequent with subsequent partitioning and
continued secretion of both fibrous
and highland material.
In the adult,
the small groups of cells are said to be
misogynists
since these represent progeny of a single
Condra side.
Yeah the matrix of island cartilage
has a unique light homogeneous
appearance.
Collage anus fibers are present but in
relatively small numbers and their refractive
indexes such that one
cannot easily distinguish between the highland matrix
and the collage.
Anus fibers.
Highland cartilage is characteristically found in
areas where a degree of rigidity is
required within the organ.
For example,
in the trachea and the larynx
on higher power.
Note the
clearness
of the highland matrix,
the cytoplasm of the cells.
It's quite clear and there is a degree of
shrinkage artifact.
The liquidity are typically
surrounded
by a deeper staining capsule
er or territorial matrix.
This deeper stained area suggests a
concentration of acid nuclear policy
Carides within the immediate vicinity of the
cells.
Now let's compare highland cartilage with fibrous,
cartilage.
Yeah.
This slide is taken from the inter vertebral disc
on low power.
The matrix appears to be quite fibrous.
In contrast to the highland cartilage,
the contra sides are
characteristically present as singles
and generally not present in misogynist groups.
When five Ricardelli just sectioned in the
appropriate plane,
it has a layered or herringbone
pattern which is unique too fibrous
card.
Yeah.
On high power we see
congress sites
within Laconi.
The predominant feature within the matrix
is a large number of collagen is
fibers.
Fibra cartilage serves as a transitional form
between cartilage and dense connective tissue
and is commonly found in the inter vertebral desk
and certain articular cartilage is.
It may also be found in sites of attachment between
certain tendons and bones.
Well.
Now compare highland cartilage and fibrous
cartilage with elastic cartilage.
This is a slide of epiglottis.
On low power we see
the stratified squamous
epithelium,
underlying loose connective tissue
and the lack of cartilage
note the characteristics common to all
types of cartilage.
The overlying pericardium
and the congress sides
present within the Laconi.
On the high power objective we see
the more intensely stained
capsule or zone.
And I.
Sergeant.
Is groups of cartilage cells
in the inter territorial matrix
between groups of cells.
We can now make out fibrous elements
composed primarily of elastic
fibers,
elastic cartilage is characteristically found in
areas in which flexibility
and elasticity is required,
such as in the internal ear
epiglottis or in the car Nicollet and
cuneiform cartilage is.
Mhm.
Yeah.
In this electron micrografx from an area of
highland cartilage we can see
to Kandra sides.
Mhm.
There is a large accumulation
unlimited within the cytoplasm
of each,
no the nuclear displacement
and the presence of short
micro villi extending from the cytoplasm
into the surrounding capsule
er Area.
This capsule er area consists of collagen
is fibers oriented
around individual Condra sides.
These oriented fibers then blend
with the felt work of randomly disposed
collagen fibers.
In this area we
see fiber sites located
within the surrounding Peric Andrea.
This completes the section on cartilage.