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			<p begin="00:00:00.000" end="00:00:30.000" style="1">*This machine-generated transcript may have errors. If remediation or a manually-generated transcript is needed, please contact NLM Support at https://support.nlm.nih.gov.*</p>
			<p begin="00:00:24.940" end="00:00:27.770" style="1">we&apos;re gonna talk today about double contrast </p>
			<p begin="00:00:27.770" end="00:00:30.160" style="1">examinations of the gastrointestinal tract </p>
			<p begin="00:00:30.840" end="00:00:33.780" style="1">for the non radiologic people here </p>
			<p begin="00:00:33.780" end="00:00:34.390" style="1">in the audience.</p>
			<p begin="00:00:34.390" end="00:00:36.300" style="1">Some of this will probably be review,</p>
			<p begin="00:00:36.850" end="00:00:39.830" style="1">some will be new material and I hope </p>
			<p begin="00:00:39.840" end="00:00:42.530" style="1">hopefully it&apos;s timely as virtually </p>
			<p begin="00:00:42.530" end="00:00:45.050" style="1">everybody at one time or another does order </p>
			<p begin="00:00:45.540" end="00:00:47.860" style="1">gastrointestinal studies on their </p>
			<p begin="00:00:47.870" end="00:00:50.830" style="1">patients for a variety of reasons.</p>
			<p begin="00:00:50.840" end="00:00:53.780" style="1">Obviously this is basically a radiologic </p>
			<p begin="00:00:53.790" end="00:00:54.480" style="1">talk,</p>
			<p begin="00:00:54.500" end="00:00:57.460" style="1">but I will orient as much as possible to </p>
			<p begin="00:00:57.460" end="00:00:57.940" style="1">it,</p>
			<p begin="00:00:57.950" end="00:01:00.870" style="1">to the clinicians uh when </p>
			<p begin="00:01:00.880" end="00:01:03.380" style="1">appropriate times make themselves </p>
			<p begin="00:01:03.380" end="00:01:03.920" style="1">available.</p>
			<p begin="00:01:04.330" end="00:01:07.030" style="1">I have really two themes that go out </p>
			<p begin="00:01:07.040" end="00:01:09.960" style="1">through this entire presentation and that </p>
			<p begin="00:01:09.960" end="00:01:12.880" style="1">is um double contrast techniques </p>
			<p begin="00:01:13.220" end="00:01:16.080" style="1">may be performed by any interested radiology </p>
			<p begin="00:01:16.090" end="00:01:16.870" style="1">department.</p>
			<p begin="00:01:16.880" end="00:01:18.760" style="1">They are not difficult to do.</p>
			<p begin="00:01:19.140" end="00:01:22.070" style="1">The reason I tell that to you clinically is that if you&apos;re ever working </p>
			<p begin="00:01:22.070" end="00:01:24.870" style="1">at other institutions and </p>
			<p begin="00:01:24.880" end="00:01:27.220" style="1">perhaps the radiology department is not perform these </p>
			<p begin="00:01:27.220" end="00:01:27.920" style="1">techniques,</p>
			<p begin="00:01:29.040" end="00:01:29.900" style="1">you know,</p>
			<p begin="00:01:29.900" end="00:01:31.530" style="1">that they can be performed with these.</p>
			<p begin="00:01:31.530" end="00:01:34.100" style="1">There there may be reasons why they don&apos;t perform them or differences in </p>
			<p begin="00:01:34.100" end="00:01:34.670" style="1">philosophy,</p>
			<p begin="00:01:34.670" end="00:01:36.980" style="1">but they can technically be performed readily.</p>
			<p begin="00:01:37.350" end="00:01:40.140" style="1">And the second theme is that uh at least </p>
			<p begin="00:01:40.140" end="00:01:41.240" style="1">in my opinion,</p>
			<p begin="00:01:41.240" end="00:01:42.180" style="1">in many instances,</p>
			<p begin="00:01:42.180" end="00:01:44.510" style="1">the diagnostic capabilities </p>
			<p begin="00:01:44.510" end="00:01:45.540" style="1">of G.</p>
			<p begin="00:01:45.540" end="00:01:48.350" style="1">I tract radiology are extended with these </p>
			<p begin="00:01:48.360" end="00:01:49.210" style="1">techniques.</p>
			<p begin="00:01:50.040" end="00:01:50.450" style="1">So,</p>
			<p begin="00:01:50.450" end="00:01:53.250" style="1">if we could have the first slide and the lights down,</p>
			<p begin="00:01:54.040" end="00:01:54.490" style="1">like </p>
			<p begin="00:01:58.340" end="00:02:00.900" style="1">double contrast examinations of the gastrointestinal </p>
			<p begin="00:02:00.910" end="00:02:03.890" style="1">tract can be performed virtually the entire gastrointestinal </p>
			<p begin="00:02:03.890" end="00:02:04.160" style="1">tract,</p>
			<p begin="00:02:04.160" end="00:02:04.940" style="1">the esophagus,</p>
			<p begin="00:02:04.940" end="00:02:05.470" style="1">the stomach,</p>
			<p begin="00:02:05.470" end="00:02:08.440" style="1">the duodenum and colon colon air contrast </p>
			<p begin="00:02:08.440" end="00:02:10.890" style="1">work has been known about for some time now,</p>
			<p begin="00:02:11.130" end="00:02:14.020" style="1">primarily popularized in uh </p>
			<p begin="00:02:14.030" end="00:02:14.510" style="1">europe.</p>
			<p begin="00:02:14.510" end="00:02:14.860" style="1">However,</p>
			<p begin="00:02:14.860" end="00:02:17.860" style="1">I think in this country it&apos;s been generally somewhat under utilized,</p>
			<p begin="00:02:18.240" end="00:02:21.200" style="1">but now there are techniques available to study these </p>
			<p begin="00:02:21.200" end="00:02:23.980" style="1">various sites with these techniques.</p>
			<p begin="00:02:23.990" end="00:02:24.750" style="1">Next line </p>
			<p begin="00:02:27.740" end="00:02:28.200" style="1">first,</p>
			<p begin="00:02:28.200" end="00:02:31.010" style="1">we&apos;ll talk about the esophagus and we&apos;ll follow the gastrointestinal </p>
			<p begin="00:02:31.010" end="00:02:32.630" style="1">track ab orally.</p>
			<p begin="00:02:33.010" end="00:02:35.940" style="1">There are various techniques that may be utilized in the technique that </p>
			<p begin="00:02:35.940" end="00:02:38.570" style="1">we have utilized here with considerable success </p>
			<p begin="00:02:38.930" end="00:02:41.860" style="1">is using the patient upright and </p>
			<p begin="00:02:42.240" end="00:02:45.200" style="1">having the patient hold barium in one hand and a </p>
			<p begin="00:02:45.200" end="00:02:47.360" style="1">cup and water in the other hand,</p>
			<p begin="00:02:47.740" end="00:02:50.550" style="1">patient has a mouthful of barium and then </p>
			<p begin="00:02:50.550" end="00:02:53.520" style="1">swallows the barium and quickly thereafter one mouthful of </p>
			<p begin="00:02:53.520" end="00:02:56.270" style="1">water so that you see we do not produce an heir </p>
			<p begin="00:02:56.270" end="00:02:58.840" style="1">contrast effect but rather a double contrast </p>
			<p begin="00:02:58.840" end="00:02:59.350" style="1">effect.</p>
			<p begin="00:02:59.740" end="00:03:02.590" style="1">That is the water washes through the </p>
			<p begin="00:03:02.590" end="00:03:04.670" style="1">barium that has previously been swallowed.</p>
			<p begin="00:03:04.830" end="00:03:07.710" style="1">Leaves a coating of barium on the esophagus and </p>
			<p begin="00:03:07.710" end="00:03:10.460" style="1">produces the double contrast effect we </p>
			<p begin="00:03:10.460" end="00:03:12.750" style="1">use for the variant preparation </p>
			<p begin="00:03:13.080" end="00:03:15.450" style="1">preparation that is formulated for air </p>
			<p begin="00:03:15.450" end="00:03:17.140" style="1">contrast colon work.</p>
			<p begin="00:03:17.200" end="00:03:20.040" style="1">It&apos;s a preparation that&apos;s a moderate moderately </p>
			<p begin="00:03:20.040" end="00:03:22.810" style="1">viscous and has excellent coding properties and </p>
			<p begin="00:03:22.810" end="00:03:25.090" style="1">spot films are obtained at the appropriate time.</p>
			<p begin="00:03:25.090" end="00:03:25.720" style="1">Next slide.</p>
			<p begin="00:03:27.530" end="00:03:30.330" style="1">This is a subject holding the barium in one hand and the </p>
			<p begin="00:03:30.330" end="00:03:32.910" style="1">water in the other hand taking a mouthful of </p>
			<p begin="00:03:32.910" end="00:03:33.460" style="1">barium.</p>
			<p begin="00:03:34.540" end="00:03:35.160" style="1">Next slide </p>
			<p begin="00:03:39.140" end="00:03:41.100" style="1">patient has the berry um in her mouth,</p>
			<p begin="00:03:41.110" end="00:03:44.030" style="1">water is ready and she&apos;s going to swallow the barium and </p>
			<p begin="00:03:44.030" end="00:03:47.010" style="1">follow that with a swallow of water as quickly as possible </p>
			<p begin="00:03:47.020" end="00:03:48.440" style="1">so that the water as we said,</p>
			<p begin="00:03:48.440" end="00:03:50.560" style="1">can wash the barium through next line.</p>
			<p begin="00:03:51.740" end="00:03:54.580" style="1">This is an example then of a normal double contrast to </p>
			<p begin="00:03:54.580" end="00:03:55.230" style="1">Sasha graham.</p>
			<p begin="00:03:55.230" end="00:03:57.160" style="1">A good one obtained with this technique.</p>
			<p begin="00:03:58.240" end="00:03:58.860" style="1">Next line.</p>
			<p begin="00:04:01.040" end="00:04:03.990" style="1">These are the clinical and radiologic uses uh </p>
			<p begin="00:04:04.000" end="00:04:05.970" style="1">for double contrast to soften biography.</p>
			<p begin="00:04:05.970" end="00:04:08.590" style="1">I should point out to you when when you&apos;re ordering this in your patients,</p>
			<p begin="00:04:08.590" end="00:04:09.800" style="1">we don&apos;t do this routinely.</p>
			<p begin="00:04:09.800" end="00:04:12.710" style="1">We do it if there are so fragile symptoms and </p>
			<p begin="00:04:12.710" end="00:04:15.120" style="1">or if there is a suspicious finding on a </p>
			<p begin="00:04:15.120" end="00:04:17.150" style="1">conventional esophageal examination.</p>
			<p begin="00:04:17.150" end="00:04:19.550" style="1">So it is not a routine examination in our department.</p>
			<p begin="00:04:19.550" end="00:04:21.550" style="1">As several other of these techniques are.</p>
			<p begin="00:04:22.240" end="00:04:25.090" style="1">It&apos;s obviously helpful for the detection of small esophageal </p>
			<p begin="00:04:25.090" end="00:04:25.510" style="1">tumors.</p>
			<p begin="00:04:25.510" end="00:04:28.250" style="1">I don&apos;t know that these small tumors are always early tumors,</p>
			<p begin="00:04:28.440" end="00:04:30.940" style="1">but one can detect smaller </p>
			<p begin="00:04:30.940" end="00:04:32.750" style="1">salvageable lesions with reliability.</p>
			<p begin="00:04:32.750" end="00:04:33.560" style="1">With this technique,</p>
			<p begin="00:04:33.940" end="00:04:36.810" style="1">it&apos;s helpful to delineate the morphological features </p>
			<p begin="00:04:36.970" end="00:04:38.280" style="1">of lesions in the esophagus.</p>
			<p begin="00:04:38.280" end="00:04:39.830" style="1">That is the surface characteristics.</p>
			<p begin="00:04:39.830" end="00:04:40.510" style="1">Is it smooth?</p>
			<p begin="00:04:40.510" end="00:04:41.190" style="1">Is it irregular?</p>
			<p begin="00:04:41.190" end="00:04:42.030" style="1">Is it also rated?</p>
			<p begin="00:04:42.540" end="00:04:43.320" style="1">And finally,</p>
			<p begin="00:04:43.320" end="00:04:46.090" style="1">to distinguish between mucosal and sub </p>
			<p begin="00:04:46.090" end="00:04:47.140" style="1">mucosal lesions?</p>
			<p begin="00:04:47.140" end="00:04:49.140" style="1">And I&apos;ll show you some examples of these things.</p>
			<p begin="00:04:49.430" end="00:04:52.310" style="1">And another use for this is to assess </p>
			<p begin="00:04:52.310" end="00:04:55.110" style="1">the total vertical extent of disease that is you have a </p>
			<p begin="00:04:55.110" end="00:04:55.860" style="1">neo plasm.</p>
			<p begin="00:04:56.540" end="00:04:59.230" style="1">The total vertical extent of this new plasm can be </p>
			<p begin="00:04:59.230" end="00:05:01.910" style="1">readily assessed with double contrast to soften </p>
			<p begin="00:05:01.910" end="00:05:02.410" style="1">geography.</p>
			<p begin="00:05:02.410" end="00:05:05.360" style="1">And this is obviously going to be helpful in treatment planning.</p>
			<p begin="00:05:06.040" end="00:05:06.760" style="1">Next line,</p>
			<p begin="00:05:08.740" end="00:05:11.270" style="1">this is an example of a lot dilated esophageal </p>
			<p begin="00:05:11.270" end="00:05:13.960" style="1">carcinoma that we had some time ago </p>
			<p begin="00:05:14.040" end="00:05:16.860" style="1">and this lesion would not be missed and was not </p>
			<p begin="00:05:16.860" end="00:05:17.670" style="1">missed on a conventional,</p>
			<p begin="00:05:17.670" end="00:05:18.420" style="1">say photography,</p>
			<p begin="00:05:18.420" end="00:05:21.380" style="1">but one can see it uh very readily with a </p>
			<p begin="00:05:21.380" end="00:05:23.970" style="1">double contrast technique and can tell the </p>
			<p begin="00:05:23.970" end="00:05:26.860" style="1">gross vertical limits of disease very readily here,</p>
			<p begin="00:05:27.540" end="00:05:29.790" style="1">much more readily than on the conventional technique.</p>
			<p begin="00:05:29.800" end="00:05:30.450" style="1">Next line.</p>
			<p begin="00:05:32.040" end="00:05:34.860" style="1">And this la belated mass in these various projections as an </p>
			<p begin="00:05:34.860" end="00:05:36.400" style="1">example of a carcinoma sarcoma.</p>
			<p begin="00:05:36.400" end="00:05:39.400" style="1">Now these several lesions no one is going to miss with </p>
			<p begin="00:05:39.400" end="00:05:40.510" style="1">conventional techniques,</p>
			<p begin="00:05:40.510" end="00:05:41.100" style="1">they&apos;re obvious.</p>
			<p begin="00:05:41.100" end="00:05:44.090" style="1">I think there may be more elegantly displayed here and one can see a little bit more </p>
			<p begin="00:05:44.090" end="00:05:44.700" style="1">about them.</p>
			<p begin="00:05:44.990" end="00:05:47.770" style="1">I&apos;m gonna show you some cases now where </p>
			<p begin="00:05:47.800" end="00:05:50.710" style="1">the double contrast technique was of definite value in </p>
			<p begin="00:05:50.710" end="00:05:53.380" style="1">comparison to conventional techniques.</p>
			<p begin="00:05:53.380" end="00:05:53.960" style="1">Next slide,</p>
			<p begin="00:05:55.640" end="00:05:58.560" style="1">This is a man that was being followed here for a gastric ulcer.</p>
			<p begin="00:05:58.560" end="00:06:01.350" style="1">He was referred here because it was felt that the gastric ulcer might be </p>
			<p begin="00:06:01.350" end="00:06:03.630" style="1">malignant and he did have a gastric ulcer,</p>
			<p begin="00:06:03.960" end="00:06:06.900" style="1">had a symptomatic patient </p>
			<p begin="00:06:06.900" end="00:06:09.180" style="1">in terms of his esophagus and on his esophagus,</p>
			<p begin="00:06:09.180" end="00:06:12.130" style="1">RAM had this obvious uh filling </p>
			<p begin="00:06:12.130" end="00:06:12.760" style="1">defect here.</p>
			<p begin="00:06:12.760" end="00:06:14.010" style="1">It&apos;s difficult to characterize it,</p>
			<p begin="00:06:14.010" end="00:06:16.280" style="1">but a definite filling defect there on multiple swallows.</p>
			<p begin="00:06:16.280" end="00:06:18.160" style="1">As you can see next slide </p>
			<p begin="00:06:19.440" end="00:06:21.660" style="1">and here with a double contrast techniques,</p>
			<p begin="00:06:22.040" end="00:06:24.950" style="1">we can see this lesion in profile </p>
			<p begin="00:06:25.940" end="00:06:28.180" style="1">and then interestingly we can see it on Fox here.</p>
			<p begin="00:06:28.180" end="00:06:30.670" style="1">It&apos;s a little unusual to see in esophageal lesion on fox,</p>
			<p begin="00:06:30.670" end="00:06:33.510" style="1">but this is analogous to how we see Palepoi defects in the </p>
			<p begin="00:06:33.510" end="00:06:33.990" style="1">colon.</p>
			<p begin="00:06:34.310" end="00:06:36.730" style="1">And this is a squamous carcinoma in this patient.</p>
			<p begin="00:06:36.730" end="00:06:39.460" style="1">I think that we can see this uh </p>
			<p begin="00:06:39.840" end="00:06:42.810" style="1">lesion considerably better with this technique than with a single </p>
			<p begin="00:06:42.810" end="00:06:43.950" style="1">contrast next live </p>
			<p begin="00:06:45.840" end="00:06:48.620" style="1">here&apos;s a very interesting patient and we&apos;ll use it to make another </p>
			<p begin="00:06:48.620" end="00:06:50.510" style="1">point to clinicians.</p>
			<p begin="00:06:51.040" end="00:06:54.010" style="1">This is a patient who had had a previous head neck tumor several years </p>
			<p begin="00:06:54.010" end="00:06:56.970" style="1">before he had a carcinoma of the tonsils and </p>
			<p begin="00:06:56.970" end="00:06:59.770" style="1">he was having difficulty swallowing and he indeed was </p>
			<p begin="00:06:59.770" end="00:07:00.970" style="1">having difficulty swallowing.</p>
			<p begin="00:07:00.970" end="00:07:03.600" style="1">You can see here that he&apos;s aspirated a fair amount of </p>
			<p begin="00:07:03.600" end="00:07:04.510" style="1">contrast material.</p>
			<p begin="00:07:04.510" end="00:07:07.280" style="1">We could not obtain very many films of his </p>
			<p begin="00:07:07.280" end="00:07:08.270" style="1">thoracic esophagus.</p>
			<p begin="00:07:08.270" end="00:07:10.760" style="1">But in this region once he&apos;s a little mucosal nodule </p>
			<p begin="00:07:11.140" end="00:07:13.430" style="1">and this proved to be a squamous carcinoma of the </p>
			<p begin="00:07:13.430" end="00:07:16.070" style="1">esophagus and a patient with a previous head and neck </p>
			<p begin="00:07:16.070" end="00:07:19.070" style="1">legion next slide and </p>
			<p begin="00:07:19.070" end="00:07:20.410" style="1">another more recent patient,</p>
			<p begin="00:07:20.410" end="00:07:23.340" style="1">another patient with a head and neck lesion a few </p>
			<p begin="00:07:23.350" end="00:07:24.440" style="1">years before.</p>
			<p begin="00:07:24.570" end="00:07:27.400" style="1">Again asymptomatic just being studied routinely for </p>
			<p begin="00:07:27.400" end="00:07:28.870" style="1">his head neck problem.</p>
			<p begin="00:07:28.870" end="00:07:31.790" style="1">We see this plaque like irregularity along this wall and this has </p>
			<p begin="00:07:31.790" end="00:07:34.550" style="1">been proven now to be a squamous carcinoma of the </p>
			<p begin="00:07:34.550" end="00:07:35.140" style="1">esophagus.</p>
			<p begin="00:07:35.140" end="00:07:38.020" style="1">I want to just stop here and make this point to any of </p>
			<p begin="00:07:38.020" end="00:07:39.510" style="1">the clinicians that are here </p>
			<p begin="00:07:39.870" end="00:07:42.720" style="1">who do see patients for head and </p>
			<p begin="00:07:42.720" end="00:07:43.390" style="1">neck problems,</p>
			<p begin="00:07:43.390" end="00:07:46.260" style="1">not necessarily head neck surgeons or </p>
			<p begin="00:07:47.140" end="00:07:47.340" style="1">E.</p>
			<p begin="00:07:47.340" end="00:07:47.470" style="1">N.</p>
			<p begin="00:07:47.470" end="00:07:47.670" style="1">T.</p>
			<p begin="00:07:47.670" end="00:07:50.410" style="1">People but anybody who comes in contact with these patients </p>
			<p begin="00:07:50.630" end="00:07:53.630" style="1">at the time they are initially diagnosed and thereafter when </p>
			<p begin="00:07:53.630" end="00:07:56.590" style="1">they&apos;re followed up one of the routine things that should be </p>
			<p begin="00:07:56.590" end="00:07:59.470" style="1">done with them at some regular periodicity.</p>
			<p begin="00:07:59.470" end="00:08:02.460" style="1">Maybe like every six months after the baseline examination is to </p>
			<p begin="00:08:02.460" end="00:08:05.290" style="1">do in a sofa graham because there is a definite </p>
			<p begin="00:08:05.290" end="00:08:08.120" style="1">increased incidents of esophageal carcinoma in </p>
			<p begin="00:08:08.120" end="00:08:10.650" style="1">patients with any sort of squamous head and neck tumors.</p>
			<p begin="00:08:10.940" end="00:08:13.920" style="1">And we have found a large number of them in a several year period </p>
			<p begin="00:08:13.920" end="00:08:16.860" style="1">of time where we&apos;ve been looking maybe maybe about as many as a </p>
			<p begin="00:08:16.860" end="00:08:17.320" style="1">dozen.</p>
			<p begin="00:08:17.570" end="00:08:19.760" style="1">Some of them quite small and others unfortunately,</p>
			<p begin="00:08:19.760" end="00:08:20.810" style="1">very large,</p>
			<p begin="00:08:20.810" end="00:08:21.570" style="1">bulky tumors.</p>
			<p begin="00:08:21.570" end="00:08:23.330" style="1">So this is an association,</p>
			<p begin="00:08:23.330" end="00:08:26.170" style="1">I think that it hasn&apos;t been entirely recognized here and then we need to look </p>
			<p begin="00:08:26.170" end="00:08:28.930" style="1">for it and maybe just as common as these people later </p>
			<p begin="00:08:28.930" end="00:08:31.060" style="1">developing squamous carcinomas of the lung.</p>
			<p begin="00:08:32.140" end="00:08:32.760" style="1">Next slide,</p>
			<p begin="00:08:34.340" end="00:08:35.420" style="1">another patient,</p>
			<p begin="00:08:35.430" end="00:08:38.380" style="1">this patient on multiple barium swallows had this </p>
			<p begin="00:08:38.380" end="00:08:40.440" style="1">vague area of narrowing in the esophagus.</p>
			<p begin="00:08:40.440" end="00:08:43.440" style="1">It was definite but not hard to characterize it.</p>
			<p begin="00:08:43.450" end="00:08:44.150" style="1">Next slide,</p>
			<p begin="00:08:45.440" end="00:08:48.160" style="1">mucosal pattern through this area was entirely normal.</p>
			<p begin="00:08:49.440" end="00:08:50.160" style="1">Next slide,</p>
			<p begin="00:08:51.040" end="00:08:52.610" style="1">but on a double contrast study,</p>
			<p begin="00:08:52.610" end="00:08:55.010" style="1">we can see some additional findings on the left here,</p>
			<p begin="00:08:55.010" end="00:08:57.570" style="1">we can see some shouldering effect that wasn&apos;t appreciated </p>
			<p begin="00:08:57.580" end="00:08:58.970" style="1">on the barren field study.</p>
			<p begin="00:08:58.970" end="00:09:01.520" style="1">And we see some irregularities on the contour of the </p>
			<p begin="00:09:01.520" end="00:09:02.950" style="1">esophagus on the opposite side.</p>
			<p begin="00:09:03.340" end="00:09:06.060" style="1">And this is another squamous carcinoma of the esophagus.</p>
			<p begin="00:09:06.740" end="00:09:07.460" style="1">Next live,</p>
			<p begin="00:09:08.640" end="00:09:09.810" style="1">here&apos;s an interesting patient.</p>
			<p begin="00:09:09.810" end="00:09:12.660" style="1">This is a brother of a physician here in this hospital </p>
			<p begin="00:09:12.670" end="00:09:15.260" style="1">who had this vision was examined at another </p>
			<p begin="00:09:15.260" end="00:09:17.940" style="1">hospital and had this filling defect in the </p>
			<p begin="00:09:17.940" end="00:09:18.680" style="1">esophagus.</p>
			<p begin="00:09:19.240" end="00:09:20.950" style="1">This filling defect identified.</p>
			<p begin="00:09:21.340" end="00:09:24.310" style="1">He was referred here and had some studies done </p>
			<p begin="00:09:24.310" end="00:09:24.540" style="1">here.</p>
			<p begin="00:09:24.540" end="00:09:27.300" style="1">Next line on this double </p>
			<p begin="00:09:27.300" end="00:09:28.070" style="1">contrast study,</p>
			<p begin="00:09:28.070" end="00:09:30.960" style="1">we see this nice smooth interim euro lesion.</p>
			<p begin="00:09:31.340" end="00:09:34.300" style="1">If you look very carefully here and I hope it projects There&apos;s another </p>
			<p begin="00:09:34.670" end="00:09:36.430" style="1">thing staring at us on foss.</p>
			<p begin="00:09:37.440" end="00:09:40.420" style="1">Next live turning the </p>
			<p begin="00:09:40.420" end="00:09:42.130" style="1">patient into the opposite of liquidy.</p>
			<p begin="00:09:42.360" end="00:09:43.560" style="1">We see the other lesion.</p>
			<p begin="00:09:44.150" end="00:09:44.340" style="1">Yes,</p>
			<p begin="00:09:44.340" end="00:09:44.660" style="1">sir.</p>
			<p begin="00:09:45.140" end="00:09:47.990" style="1">Are to lie on my mama&apos;s in this patient&apos;s esophagus,</p>
			<p begin="00:09:48.540" end="00:09:51.360" style="1">only the second one being recognized with double contrast </p>
			<p begin="00:09:51.360" end="00:09:51.740" style="1">study.</p>
			<p begin="00:09:51.750" end="00:09:52.350" style="1">Next slide,</p>
			<p begin="00:09:54.240" end="00:09:56.660" style="1">here&apos;s another interesting patient that has this obvious </p>
			<p begin="00:09:56.670" end="00:09:59.470" style="1">fungal irregular carcinoma with </p>
			<p begin="00:09:59.470" end="00:10:02.420" style="1">some extension seems to be going up into the esophagus as they </p>
			<p begin="00:10:02.420" end="00:10:03.470" style="1">commonly do.</p>
			<p begin="00:10:03.790" end="00:10:06.690" style="1">Next slide films of the </p>
			<p begin="00:10:06.690" end="00:10:09.320" style="1">esophagus do show some minor marginally </p>
			<p begin="00:10:09.320" end="00:10:10.030" style="1">regularities.</p>
			<p begin="00:10:10.030" end="00:10:12.450" style="1">And one would be suspicious that there is disease there.</p>
			<p begin="00:10:12.450" end="00:10:15.360" style="1">But it&apos;s a little hard to define next line.</p>
			<p begin="00:10:16.540" end="00:10:17.030" style="1">But again,</p>
			<p begin="00:10:17.030" end="00:10:18.180" style="1">with double contrast study,</p>
			<p begin="00:10:18.180" end="00:10:20.390" style="1">we can readily outline the total vertical extent.</p>
			<p begin="00:10:20.390" end="00:10:23.230" style="1">This is not a good study because this patient had relative obstruction </p>
			<p begin="00:10:23.230" end="00:10:23.570" style="1">here.</p>
			<p begin="00:10:23.570" end="00:10:25.850" style="1">One can always obtain a beautiful study.</p>
			<p begin="00:10:25.850" end="00:10:28.590" style="1">But even in a study here that somewhat compromised by an </p>
			<p begin="00:10:28.590" end="00:10:29.200" style="1">obstruction,</p>
			<p begin="00:10:29.310" end="00:10:31.900" style="1">one can still see this Neil players from crawling up the </p>
			<p begin="00:10:31.900" end="00:10:32.690" style="1">esophagus.</p>
			<p begin="00:10:34.240" end="00:10:36.660" style="1">This piece of tumor is up here.</p>
			<p begin="00:10:37.140" end="00:10:40.020" style="1">So we can see that virtually the distal half the esophagus is </p>
			<p begin="00:10:40.020" end="00:10:42.920" style="1">involved by this gastric nia plasm that&apos;s readily </p>
			<p begin="00:10:42.920" end="00:10:45.850" style="1">identified with double contrast examination next lot.</p>
			<p begin="00:10:47.740" end="00:10:48.630" style="1">And finally,</p>
			<p begin="00:10:48.630" end="00:10:50.850" style="1">just in terms of inflammatory disease.</p>
			<p begin="00:10:51.080" end="00:10:53.570" style="1">This is a patient with candid diocese and we see a nice </p>
			<p begin="00:10:53.570" end="00:10:56.460" style="1">cobblestone pattern throughout the assad because in </p>
			<p begin="00:10:56.470" end="00:10:58.560" style="1">this patient next line.</p>
			<p begin="00:10:59.740" end="00:11:02.320" style="1">So in summary relating to the esophagus </p>
			<p begin="00:11:02.620" end="00:11:05.460" style="1">double contrast of so photography is simple to perform.</p>
			<p begin="00:11:06.740" end="00:11:09.620" style="1">We do the technique of barium and water with successive </p>
			<p begin="00:11:09.620" end="00:11:12.290" style="1">swallows and we find that it is a useful </p>
			<p begin="00:11:12.290" end="00:11:14.600" style="1">adjunct to the morphological examination of the </p>
			<p begin="00:11:14.600" end="00:11:17.170" style="1">esophagus for the detection of small </p>
			<p begin="00:11:17.170" end="00:11:18.370" style="1">esophageal tumors.</p>
			<p begin="00:11:18.380" end="00:11:20.360" style="1">Hopefully early in some cases </p>
			<p begin="00:11:20.840" end="00:11:23.660" style="1">defining the morphological features of the tumors </p>
			<p begin="00:11:24.440" end="00:11:27.400" style="1">and finally the vertical extent of disease in </p>
			<p begin="00:11:27.400" end="00:11:28.190" style="1">the esophagus.</p>
			<p begin="00:11:28.640" end="00:11:29.360" style="1">Next slide,</p>
			<p begin="00:11:30.840" end="00:11:33.560" style="1">we&apos;ll go on to the stomach now and talk about </p>
			<p begin="00:11:33.940" end="00:11:36.550" style="1">air contrast or double contrast exams of the </p>
			<p begin="00:11:36.550" end="00:11:37.060" style="1">stomach.</p>
			<p begin="00:11:37.720" end="00:11:38.600" style="1">In this case,</p>
			<p begin="00:11:38.610" end="00:11:40.950" style="1">the way the technique is performed on your patients.</p>
			<p begin="00:11:41.440" end="00:11:44.250" style="1">We use 2-3 ounces of a high density berry.</p>
			<p begin="00:11:44.250" end="00:11:46.660" style="1">Um that has certain coding properties for the stomach </p>
			<p begin="00:11:47.340" end="00:11:50.320" style="1">to the barium is added an anti foaming agent that we&apos;ll discuss in </p>
			<p begin="00:11:50.320" end="00:11:52.750" style="1">a moment and we use a gas preparation </p>
			<p begin="00:11:52.750" end="00:11:55.710" style="1">effervescent powders to produce the gas in the </p>
			<p begin="00:11:55.710" end="00:11:58.690" style="1">stomach patient ingested the gas </p>
			<p begin="00:11:58.690" end="00:12:01.690" style="1">preparation the effervescent powders and follows this with a </p>
			<p begin="00:12:01.690" end="00:12:04.490" style="1">barium patients turned several times to make sure the </p>
			<p begin="00:12:04.490" end="00:12:07.350" style="1">stomach is coded and to dissipate the bubbles and then </p>
			<p begin="00:12:07.350" end="00:12:09.310" style="1">double contrast views are obtained.</p>
			<p begin="00:12:09.370" end="00:12:12.320" style="1">We routinely do four double contrast views </p>
			<p begin="00:12:12.650" end="00:12:15.430" style="1">in our examination and it&apos;s readily incorporated into the </p>
			<p begin="00:12:15.430" end="00:12:17.030" style="1">initial part of the examination.</p>
			<p begin="00:12:17.740" end="00:12:20.440" style="1">Blue dragon and other anti spasmodic </p>
			<p begin="00:12:20.440" end="00:12:23.420" style="1">agents may or may not be added uh to decrease </p>
			<p begin="00:12:23.420" end="00:12:26.040" style="1">gastric peristalsis uh and decrease </p>
			<p begin="00:12:26.040" end="00:12:27.730" style="1">gastric emptying if that&apos;s necessary.</p>
			<p begin="00:12:27.730" end="00:12:30.470" style="1">And we use a low killer voltage on </p>
			<p begin="00:12:30.470" end="00:12:33.220" style="1">these radiographs to obtain optimal contrast </p>
			<p begin="00:12:33.220" end="00:12:36.040" style="1">next line these are </p>
			<p begin="00:12:36.040" end="00:12:38.870" style="1">some of the preparations that have been available primarily </p>
			<p begin="00:12:38.870" end="00:12:41.680" style="1">manufactured in japan effervescent </p>
			<p begin="00:12:41.680" end="00:12:44.550" style="1">preparations and many of these had anti </p>
			<p begin="00:12:44.550" end="00:12:46.060" style="1">foam substances in them.</p>
			<p begin="00:12:46.070" end="00:12:46.760" style="1">However,</p>
			<p begin="00:12:46.760" end="00:12:49.420" style="1">they are generally not available in the United States.</p>
			<p begin="00:12:49.840" end="00:12:51.720" style="1">Uh at this time.</p>
			<p begin="00:12:51.720" end="00:12:52.760" style="1">Next slide,</p>
			<p begin="00:12:53.740" end="00:12:56.380" style="1">this is one of the preparations call unique Zorro.</p>
			<p begin="00:12:56.390" end="00:12:58.690" style="1">We see here that when the cap is opened,</p>
			<p begin="00:12:58.690" end="00:13:01.350" style="1">there are some japanese script here.</p>
			<p begin="00:13:01.350" end="00:13:03.600" style="1">A lot of people think that this is the instructions </p>
			<p begin="00:13:04.140" end="00:13:05.630" style="1">as to how to do the examination,</p>
			<p begin="00:13:05.630" end="00:13:08.560" style="1">but others feel that this perhaps represents new plans </p>
			<p begin="00:13:08.560" end="00:13:10.050" style="1">for an attack on Pearl Harbor.</p>
			<p begin="00:13:11.040" end="00:13:11.760" style="1">Next line </p>
			<p begin="00:13:13.840" end="00:13:16.710" style="1">we find that just plain old citric carbonate that one </p>
			<p begin="00:13:16.710" end="00:13:19.570" style="1">can obtain from any pharmacy is just as </p>
			<p begin="00:13:19.820" end="00:13:22.770" style="1">good as the other preparations of course here where </p>
			<p begin="00:13:22.770" end="00:13:25.260" style="1">there is no anti foam agent and one has to </p>
			<p begin="00:13:25.740" end="00:13:27.090" style="1">add the anti foam agent.</p>
			<p begin="00:13:27.090" end="00:13:30.000" style="1">We use about a teaspoonful of the gas </p>
			<p begin="00:13:30.000" end="00:13:30.960" style="1">powder next line </p>
			<p begin="00:13:33.240" end="00:13:34.800" style="1">and we add Millikan drops.</p>
			<p begin="00:13:34.800" end="00:13:35.150" style="1">In other words,</p>
			<p begin="00:13:35.150" end="00:13:37.330" style="1">this is signed with a cone to the berry,</p>
			<p begin="00:13:37.330" end="00:13:38.920" style="1">um maybe a CC or CC.</p>
			<p begin="00:13:38.920" end="00:13:41.660" style="1">And a half of these malecon drops are added to the 2 to 3 </p>
			<p begin="00:13:41.660" end="00:13:43.440" style="1">ounces of barium.</p>
			<p begin="00:13:43.580" end="00:13:44.160" style="1">Next line,</p>
			<p begin="00:13:45.040" end="00:13:45.250" style="1">yes.</p>
			<p begin="00:13:46.040" end="00:13:48.410" style="1">So the patient begins the examination </p>
			<p begin="00:13:48.420" end="00:13:51.370" style="1">with citric carbonate powders and bury him in </p>
			<p begin="00:13:51.380" end="00:13:52.050" style="1">hand.</p>
			<p begin="00:13:52.060" end="00:13:54.870" style="1">Next line she ingests the powders and </p>
			<p begin="00:13:54.870" end="00:13:57.500" style="1">drinks down the uh the barium </p>
			<p begin="00:13:57.510" end="00:14:00.170" style="1">patients place in a recumbent position and turn from the </p>
			<p begin="00:14:00.170" end="00:14:03.140" style="1">supine to the prone position and back three or </p>
			<p begin="00:14:03.140" end="00:14:06.100" style="1">four times again to achieve as good </p>
			<p begin="00:14:06.100" end="00:14:08.960" style="1">at coding as possible and to uh </p>
			<p begin="00:14:09.440" end="00:14:12.060" style="1">make the bubbles disperse that are formed by the citric </p>
			<p begin="00:14:12.060" end="00:14:12.560" style="1">carbonate.</p>
			<p begin="00:14:13.040" end="00:14:15.510" style="1">Next line and then </p>
			<p begin="00:14:15.550" end="00:14:18.180" style="1">three films in the supine and soup.</p>
			<p begin="00:14:18.180" end="00:14:21.040" style="1">I know black positions are obtained in rapid succession.</p>
			<p begin="00:14:21.040" end="00:14:23.470" style="1">One wants to do this fairly rapidly so that not much </p>
			<p begin="00:14:23.470" end="00:14:26.270" style="1">gastric emptying of either barium or </p>
			<p begin="00:14:26.280" end="00:14:28.260" style="1">uh air takes place.</p>
			<p begin="00:14:28.270" end="00:14:28.950" style="1">Next live.</p>
			<p begin="00:14:30.640" end="00:14:33.400" style="1">This would be an example of a nice double contrast </p>
			<p begin="00:14:33.410" end="00:14:36.210" style="1">gastro gram in the supine position with </p>
			<p begin="00:14:36.210" end="00:14:39.050" style="1">just a small amount of barium and not much gastric </p>
			<p begin="00:14:39.050" end="00:14:39.350" style="1">emptying.</p>
			<p begin="00:14:39.350" end="00:14:40.380" style="1">Haven&apos;t taking place.</p>
			<p begin="00:14:40.500" end="00:14:41.150" style="1">Next line.</p>
			<p begin="00:14:43.340" end="00:14:44.450" style="1">one Old Black View.</p>
			<p begin="00:14:45.440" end="00:14:48.390" style="1">Next live the other </p>
			<p begin="00:14:48.390" end="00:14:49.160" style="1">old black view.</p>
			<p begin="00:14:50.840" end="00:14:52.700" style="1">Those are three routine views we obtain.</p>
			<p begin="00:14:52.700" end="00:14:55.590" style="1">Next lied at this point we stand the patient </p>
			<p begin="00:14:55.590" end="00:14:57.750" style="1">up and obtain an upright view of the fungus.</p>
			<p begin="00:14:58.240" end="00:15:00.810" style="1">And at this point then the rest of the examination </p>
			<p begin="00:15:01.070" end="00:15:03.470" style="1">is resumed as in a conventional way.</p>
			<p begin="00:15:03.470" end="00:15:06.210" style="1">And most people would at this point do pressure,</p>
			<p begin="00:15:06.210" end="00:15:09.150" style="1">mucosal views on the on the rest of the stomach and </p>
			<p begin="00:15:09.150" end="00:15:11.420" style="1">there&apos;s just a small amount of barium in the stomach at this time.</p>
			<p begin="00:15:11.420" end="00:15:14.300" style="1">And one can readily obtain these views.</p>
			<p begin="00:15:14.300" end="00:15:14.760" style="1">Next line,</p>
			<p begin="00:15:17.340" end="00:15:20.010" style="1">I&apos;m just gonna digress here for a moment and talk </p>
			<p begin="00:15:20.010" end="00:15:23.000" style="1">about one aspect of the </p>
			<p begin="00:15:23.010" end="00:15:25.730" style="1">stomach anatomy that we&apos;ve been able to appreciate with </p>
			<p begin="00:15:25.730" end="00:15:27.740" style="1">double contrast studies of the stomach.</p>
			<p begin="00:15:27.750" end="00:15:30.710" style="1">Should say that dr Dodd stimulated this work </p>
			<p begin="00:15:30.710" end="00:15:31.430" style="1">in our department.</p>
			<p begin="00:15:31.430" end="00:15:33.060" style="1">He has been interested in this for some time.</p>
			<p begin="00:15:33.060" end="00:15:35.850" style="1">And for any of you who are further interested in this and </p>
			<p begin="00:15:35.850" end="00:15:37.410" style="1">other aspects of stomach anatomy.</p>
			<p begin="00:15:37.410" end="00:15:39.510" style="1">He&apos;s going to be talking at jesse jones </p>
			<p begin="00:15:39.940" end="00:15:42.160" style="1">library building on the first floor </p>
			<p begin="00:15:42.660" end="00:15:45.480" style="1">to the Houston Gi Forum this afternoon at three </p>
			<p begin="00:15:45.480" end="00:15:45.960" style="1">o&apos;clock.</p>
			<p begin="00:15:47.940" end="00:15:49.620" style="1">The surface of the gastric mucosa,</p>
			<p begin="00:15:49.620" end="00:15:51.270" style="1">my gastric mucosa and yours.</p>
			<p begin="00:15:51.270" end="00:15:54.210" style="1">Everybody&apos;s is subdivided in addition to the Rue Guy that </p>
			<p begin="00:15:54.210" end="00:15:57.050" style="1">everybody knows about into small ovoid or </p>
			<p begin="00:15:57.050" end="00:15:59.970" style="1">political islands by a complex intersecting series </p>
			<p begin="00:15:59.970" end="00:16:01.160" style="1">of shallow grooves.</p>
			<p begin="00:16:01.840" end="00:16:04.680" style="1">The islands that will show you in a moment or turned the area </p>
			<p begin="00:16:04.680" end="00:16:07.500" style="1">gas tricky and the surrounding grooves are turned the </p>
			<p begin="00:16:07.500" end="00:16:09.860" style="1">salsa gastric next lot </p>
			<p begin="00:16:11.840" end="00:16:14.740" style="1">this is a stomach that&apos;s been opened </p>
			<p begin="00:16:14.740" end="00:16:14.970" style="1">up.</p>
			<p begin="00:16:14.970" end="00:16:16.030" style="1">And if you look carefully,</p>
			<p begin="00:16:16.030" end="00:16:16.220" style="1">you know,</p>
			<p begin="00:16:16.220" end="00:16:17.030" style="1">there are obvious ruby.</p>
			<p begin="00:16:17.030" end="00:16:20.000" style="1">I hear that everybody knows about in the stomach of course,</p>
			<p begin="00:16:20.000" end="00:16:22.480" style="1">and that we use to make diagnoses with.</p>
			<p begin="00:16:22.490" end="00:16:24.780" style="1">But there are other little </p>
			<p begin="00:16:25.340" end="00:16:26.280" style="1">islands here.</p>
			<p begin="00:16:26.290" end="00:16:26.740" style="1">In other words,</p>
			<p begin="00:16:26.740" end="00:16:29.640" style="1">a fine mucosal relief pattern in and amongst the </p>
			<p begin="00:16:29.640" end="00:16:32.060" style="1">Rue Guy and where the rug I are not in the stomach.</p>
			<p begin="00:16:32.440" end="00:16:33.060" style="1">Next line,</p>
			<p begin="00:16:35.040" end="00:16:37.480" style="1">this is the same stomach painted with </p>
			<p begin="00:16:37.480" end="00:16:39.920" style="1">barium and one can appreciate this </p>
			<p begin="00:16:39.920" end="00:16:42.540" style="1">network pattern uh in the </p>
			<p begin="00:16:42.540" end="00:16:45.430" style="1">stomach amongst the Rue Guy and in between them and on </p>
			<p begin="00:16:45.430" end="00:16:45.630" style="1">them,</p>
			<p begin="00:16:45.630" end="00:16:46.150" style="1">et cetera.</p>
			<p begin="00:16:46.160" end="00:16:46.770" style="1">Next line </p>
			<p begin="00:16:48.940" end="00:16:51.760" style="1">here is a close up of one aspect or one portion of the </p>
			<p begin="00:16:51.760" end="00:16:52.690" style="1">body of that stomach.</p>
			<p begin="00:16:52.690" end="00:16:54.350" style="1">So like here&apos;s a gastric crew guy.</p>
			<p begin="00:16:54.350" end="00:16:57.310" style="1">And there&apos;s one and then one can see on the Rue Guy and in </p>
			<p begin="00:16:57.310" end="00:17:00.160" style="1">between them these little political islands of </p>
			<p begin="00:17:00.160" end="00:17:00.490" style="1">tissue,</p>
			<p begin="00:17:00.490" end="00:17:01.840" style="1">the fine mucosal relief,</p>
			<p begin="00:17:01.840" end="00:17:04.610" style="1">the area gastric and then surrounding and </p>
			<p begin="00:17:04.620" end="00:17:07.300" style="1">actually making up these little islands are these </p>
			<p begin="00:17:07.310" end="00:17:10.060" style="1">intersecting grooves called the salsa </p>
			<p begin="00:17:10.060" end="00:17:10.770" style="1">gastric E.</p>
			<p begin="00:17:11.240" end="00:17:12.770" style="1">Those salty gastric.</p>
			<p begin="00:17:12.770" end="00:17:15.610" style="1">Those little tunnels is where the barium goes to </p>
			<p begin="00:17:15.610" end="00:17:16.960" style="1">make that network pattern.</p>
			<p begin="00:17:17.340" end="00:17:17.960" style="1">Next line.</p>
			<p begin="00:17:19.540" end="00:17:22.290" style="1">And this is a close up in vitro painted </p>
			<p begin="00:17:22.290" end="00:17:25.040" style="1">view of that portion of the stomach showing </p>
			<p begin="00:17:25.040" end="00:17:26.100" style="1">that appearance.</p>
			<p begin="00:17:26.840" end="00:17:27.460" style="1">Next line.</p>
			<p begin="00:17:29.540" end="00:17:32.480" style="1">Dr James Anderson in uh the </p>
			<p begin="00:17:32.480" end="00:17:35.040" style="1">laboratory associated with the </p>
			<p begin="00:17:35.050" end="00:17:36.810" style="1">diagnostic radiology department.</p>
			<p begin="00:17:36.820" end="00:17:39.220" style="1">Uh did some scanning electron </p>
			<p begin="00:17:39.230" end="00:17:41.910" style="1">microscopy of some stomachs.</p>
			<p begin="00:17:42.140" end="00:17:44.960" style="1">And this is an interesting appearance of this </p>
			<p begin="00:17:44.970" end="00:17:47.260" style="1">pattern with a scanning electron </p>
			<p begin="00:17:47.260" end="00:17:48.110" style="1">microscopy.</p>
			<p begin="00:17:48.640" end="00:17:51.040" style="1">One of these is an area gastric E.</p>
			<p begin="00:17:51.040" end="00:17:53.050" style="1">These are one of these islands blown up.</p>
			<p begin="00:17:54.140" end="00:17:55.670" style="1">And here are these tunnels.</p>
			<p begin="00:17:56.520" end="00:17:59.150" style="1">These intersecting grooves the salsa gastric E.</p>
			<p begin="00:17:59.150" end="00:17:59.940" style="1">And we can notice.</p>
			<p begin="00:17:59.940" end="00:18:02.870" style="1">Then each area gastric itself has a </p>
			<p begin="00:18:02.870" end="00:18:05.490" style="1">convoluted patterns like each area gastric has an area </p>
			<p begin="00:18:05.490" end="00:18:06.950" style="1">gastric pattern of itself.</p>
			<p begin="00:18:07.340" end="00:18:09.700" style="1">But we see a convoluted pattern on each area.</p>
			<p begin="00:18:09.700" end="00:18:11.360" style="1">Gastric Next line </p>
			<p begin="00:18:13.040" end="00:18:14.610" style="1">here&apos;s a close up of one of those.</p>
			<p begin="00:18:14.610" end="00:18:16.060" style="1">This is one area gas tricky.</p>
			<p begin="00:18:17.940" end="00:18:20.860" style="1">Here are these tunnels alongside the salsa gas tricky </p>
			<p begin="00:18:20.860" end="00:18:21.690" style="1">these grooves.</p>
			<p begin="00:18:22.240" end="00:18:22.580" style="1">Okay.</p>
			<p begin="00:18:22.580" end="00:18:24.450" style="1">And then we see this convoluted pattern.</p>
			<p begin="00:18:24.650" end="00:18:26.960" style="1">If you notice amongst the convoluted pattern,</p>
			<p begin="00:18:26.960" end="00:18:27.730" style="1">our little pits,</p>
			<p begin="00:18:27.730" end="00:18:28.590" style="1">little depressions.</p>
			<p begin="00:18:28.590" end="00:18:30.120" style="1">Those are the gastric pits.</p>
			<p begin="00:18:30.460" end="00:18:33.130" style="1">Those are the openings on the gastric </p>
			<p begin="00:18:33.130" end="00:18:36.030" style="1">mucosal surface into which gastric </p>
			<p begin="00:18:36.030" end="00:18:38.620" style="1">glands drain so that if you can see here </p>
			<p begin="00:18:38.630" end="00:18:40.410" style="1">each area gastric E.</p>
			<p begin="00:18:40.410" end="00:18:43.380" style="1">Each little island maybe has a dozen Of these </p>
			<p begin="00:18:43.380" end="00:18:46.370" style="1">gastric pits into which gastric Glands one or </p>
			<p begin="00:18:46.370" end="00:18:48.360" style="1">more drain next slide.</p>
			<p begin="00:18:49.840" end="00:18:52.180" style="1">So this schematic drawing </p>
			<p begin="00:18:52.180" end="00:18:54.340" style="1">summarizes what we&apos;ve just said.</p>
			<p begin="00:18:54.340" end="00:18:57.300" style="1">Then one of these islands is the area gas tricky.</p>
			<p begin="00:18:57.580" end="00:19:00.560" style="1">And then one can see these little black dots </p>
			<p begin="00:19:00.560" end="00:19:01.960" style="1">representing the cell site.</p>
			<p begin="00:19:01.970" end="00:19:04.780" style="1">Excuse me representing the gastric pits.</p>
			<p begin="00:19:04.780" end="00:19:06.890" style="1">And then we can notice here in the cross section.</p>
			<p begin="00:19:07.340" end="00:19:10.190" style="1">One or more gastric glands drains into each one of </p>
			<p begin="00:19:10.190" end="00:19:11.410" style="1">these gastric pits.</p>
			<p begin="00:19:12.240" end="00:19:15.150" style="1">Thanks line Radio </p>
			<p begin="00:19:15.150" end="00:19:17.890" style="1">graphically we can identify this pattern if we </p>
			<p begin="00:19:17.890" end="00:19:20.850" style="1">do double contrast techniques and have </p>
			<p begin="00:19:20.850" end="00:19:23.690" style="1">good coding variant preparations that are not too viscous so </p>
			<p begin="00:19:23.690" end="00:19:26.660" style="1">that the the barry um </p>
			<p begin="00:19:26.660" end="00:19:29.070" style="1">can enter the shallow sell side gastric.</p>
			<p begin="00:19:29.070" end="00:19:31.810" style="1">And we have identified three arbitrary </p>
			<p begin="00:19:31.810" end="00:19:32.370" style="1">patterns.</p>
			<p begin="00:19:32.370" end="00:19:34.790" style="1">We&apos;ve talked about a fine pattern,</p>
			<p begin="00:19:34.790" end="00:19:36.790" style="1">a course pattern in a nodule or pattern.</p>
			<p begin="00:19:36.790" end="00:19:39.790" style="1">And you will see this in your report sometime where we talk about </p>
			<p begin="00:19:39.790" end="00:19:42.560" style="1">a course fine mucosal relief pattern </p>
			<p begin="00:19:42.570" end="00:19:45.200" style="1">or a coarse or fine area gas tricky </p>
			<p begin="00:19:45.200" end="00:19:45.670" style="1">pattern.</p>
			<p begin="00:19:47.640" end="00:19:49.920" style="1">Next lot here are some </p>
			<p begin="00:19:49.920" end="00:19:51.000" style="1">examples.</p>
			<p begin="00:19:51.140" end="00:19:53.890" style="1">This fine little network pattern in the distal </p>
			<p begin="00:19:53.890" end="00:19:56.820" style="1">stomach here is an example of a of an average </p>
			<p begin="00:19:56.820" end="00:19:59.460" style="1">fine gastric find relief pattern.</p>
			<p begin="00:19:59.840" end="00:20:02.590" style="1">This would be uh not very </p>
			<p begin="00:20:02.600" end="00:20:03.340" style="1">spectacular.</p>
			<p begin="00:20:03.340" end="00:20:06.130" style="1">And we see this I guess in about 50% of our cases </p>
			<p begin="00:20:06.140" end="00:20:08.750" style="1">uh using double contrast </p>
			<p begin="00:20:08.750" end="00:20:09.390" style="1">techniques.</p>
			<p begin="00:20:09.430" end="00:20:12.160" style="1">Next live this would be a </p>
			<p begin="00:20:12.160" end="00:20:15.110" style="1">coarser pattern where the islands themselves are larger and the </p>
			<p begin="00:20:15.110" end="00:20:18.050" style="1">grooves themselves are denser appear more </p>
			<p begin="00:20:18.050" end="00:20:18.600" style="1">coarsened.</p>
			<p begin="00:20:19.640" end="00:20:20.360" style="1">Next line.</p>
			<p begin="00:20:22.240" end="00:20:24.810" style="1">Another example of a course area gastric </p>
			<p begin="00:20:24.820" end="00:20:25.360" style="1">pattern.</p>
			<p begin="00:20:27.740" end="00:20:30.690" style="1">Next line and finally </p>
			<p begin="00:20:30.690" end="00:20:32.770" style="1">a not very frequent appearance,</p>
			<p begin="00:20:32.770" end="00:20:35.480" style="1">the nodule er appearance of the </p>
			<p begin="00:20:35.490" end="00:20:37.960" style="1">fine mucosal relief pattern of the stomach.</p>
			<p begin="00:20:39.340" end="00:20:40.540" style="1">Now,</p>
			<p begin="00:20:40.570" end="00:20:42.690" style="1">uh anatomically </p>
			<p begin="00:20:42.960" end="00:20:45.870" style="1">this is interesting and I think certainly one </p>
			<p begin="00:20:45.870" end="00:20:48.740" style="1">thing it helps us with is that if we see this </p>
			<p begin="00:20:48.740" end="00:20:49.630" style="1">with regularity,</p>
			<p begin="00:20:49.780" end="00:20:50.530" style="1">we know,</p>
			<p begin="00:20:50.530" end="00:20:53.300" style="1">then we have an objective criterion to say that we are </p>
			<p begin="00:20:53.300" end="00:20:55.800" style="1">achieving excellent double contrast </p>
			<p begin="00:20:55.800" end="00:20:57.080" style="1">examinations of the stomach.</p>
			<p begin="00:20:57.080" end="00:20:58.350" style="1">If one can see this pattern,</p>
			<p begin="00:20:58.350" end="00:21:00.770" style="1">one knows he&apos;s achieving ah </p>
			<p begin="00:21:01.140" end="00:21:03.660" style="1">good double contrast work of the stomach </p>
			<p begin="00:21:04.240" end="00:21:07.120" style="1">what their functional significance is and if they can </p>
			<p begin="00:21:07.120" end="00:21:10.060" style="1">be used in diagnosis is </p>
			<p begin="00:21:10.060" end="00:21:11.950" style="1">a little more questionable at this time,</p>
			<p begin="00:21:11.950" end="00:21:14.920" style="1">we have had some cases where the pattern&apos;s been course </p>
			<p begin="00:21:14.920" end="00:21:17.250" style="1">or Nigel er that has been diagnosis gastritis.</p>
			<p begin="00:21:17.510" end="00:21:20.140" style="1">We&apos;ve had one or two cases where it&apos;s been helpful in malignant </p>
			<p begin="00:21:20.140" end="00:21:20.770" style="1">disease,</p>
			<p begin="00:21:21.140" end="00:21:23.740" style="1">but at this time it would be hard to make a </p>
			<p begin="00:21:23.740" end="00:21:26.490" style="1">definitive statement about its real diagnosable </p>
			<p begin="00:21:26.490" end="00:21:26.900" style="1">value.</p>
			<p begin="00:21:26.900" end="00:21:27.130" style="1">Well,</p>
			<p begin="00:21:27.130" end="00:21:29.940" style="1">sometimes in our reports say this to the </p>
			<p begin="00:21:29.940" end="00:21:30.500" style="1">clinicians,</p>
			<p begin="00:21:30.600" end="00:21:33.600" style="1">you&apos;ll see a report that discusses this pattern the fund because of </p>
			<p begin="00:21:33.600" end="00:21:35.450" style="1">relief pattern of the area gastric pattern.</p>
			<p begin="00:21:35.840" end="00:21:38.730" style="1">And there will be a statement made that it could suggest </p>
			<p begin="00:21:39.050" end="00:21:41.740" style="1">diagnose of gastritis and you have to correlate that </p>
			<p begin="00:21:41.740" end="00:21:43.900" style="1">clinically with your clinical findings.</p>
			<p begin="00:21:44.050" end="00:21:46.900" style="1">But at this time there is no definitive statement that can be </p>
			<p begin="00:21:46.900" end="00:21:49.410" style="1">made regarding its its functional </p>
			<p begin="00:21:49.420" end="00:21:51.550" style="1">significance as diagnostic significance.</p>
			<p begin="00:21:51.550" end="00:21:52.060" style="1">Next line,</p>
			<p begin="00:21:54.340" end="00:21:54.740" style="1">okay,</p>
			<p begin="00:21:54.740" end="00:21:54.920" style="1">now,</p>
			<p begin="00:21:54.920" end="00:21:57.750" style="1">back to double contrast gastro graffiti and some </p>
			<p begin="00:21:57.760" end="00:22:00.650" style="1">quick examples of diagnoses that are made very </p>
			<p begin="00:22:00.650" end="00:22:03.420" style="1">readily with double contrast uh studies </p>
			<p begin="00:22:03.430" end="00:22:04.600" style="1">here on the post year.</p>
			<p begin="00:22:04.600" end="00:22:07.480" style="1">While the stomach is the evidence of a healed ulcer </p>
			<p begin="00:22:07.890" end="00:22:10.690" style="1">with multiple radiating folds right into a little gastric </p>
			<p begin="00:22:10.700" end="00:22:11.050" style="1">pit.</p>
			<p begin="00:22:12.740" end="00:22:13.460" style="1">Next slide </p>
			<p begin="00:22:15.940" end="00:22:18.660" style="1">here&apos;s another lesion on the posterior wall of the </p>
			<p begin="00:22:18.660" end="00:22:19.120" style="1">stomach,</p>
			<p begin="00:22:19.120" end="00:22:21.910" style="1">a central ulcer crater with radiating folds.</p>
			<p begin="00:22:22.530" end="00:22:23.980" style="1">This surprises.</p>
			<p begin="00:22:23.980" end="00:22:24.430" style="1">Incidentally,</p>
			<p begin="00:22:24.430" end="00:22:27.360" style="1">one can see this network pattern the area gas tricky and the more distal </p>
			<p begin="00:22:27.360" end="00:22:27.770" style="1">stomach.</p>
			<p begin="00:22:28.140" end="00:22:29.750" style="1">We thought that this,</p>
			<p begin="00:22:29.760" end="00:22:30.320" style="1">you know,</p>
			<p begin="00:22:30.320" end="00:22:33.020" style="1">in this projection at least had the appearance of a </p>
			<p begin="00:22:33.030" end="00:22:35.010" style="1">benign ulcer with radiating foals </p>
			<p begin="00:22:35.300" end="00:22:38.160" style="1">dr nelson and his group endoscope this </p>
			<p begin="00:22:38.160" end="00:22:40.960" style="1">patient and took some biopsies and I understand that on this </p>
			<p begin="00:22:40.970" end="00:22:43.800" style="1">one or two of the folds up super early there </p>
			<p begin="00:22:43.800" end="00:22:46.790" style="1">was lymphoma patient did have known </p>
			<p begin="00:22:46.790" end="00:22:49.790" style="1">lymphoma in his liver and this turned out to be a lymphoma.</p>
			<p begin="00:22:49.790" end="00:22:52.670" style="1">This involvement of the stomach and this unusual presentation </p>
			<p begin="00:22:53.040" end="00:22:55.360" style="1">of a ulcer with radiating folds.</p>
			<p begin="00:22:55.370" end="00:22:56.060" style="1">Next line,</p>
			<p begin="00:22:58.240" end="00:22:59.620" style="1">here&apos;s a very interesting case.</p>
			<p begin="00:22:59.620" end="00:23:02.540" style="1">It&apos;s not something that&apos;s going to be seen very much probably at </p>
			<p begin="00:23:02.550" end="00:23:05.260" style="1">this hospital but will be seen at other hospitals where this </p>
			<p begin="00:23:05.260" end="00:23:06.400" style="1">technique is performed.</p>
			<p begin="00:23:06.630" end="00:23:09.550" style="1">This is a standard right Ontario </p>
			<p begin="00:23:09.550" end="00:23:11.910" style="1">black view of the stomach that&apos;s perfectly normal in a patient.</p>
			<p begin="00:23:11.910" end="00:23:12.560" style="1">Next line.</p>
			<p begin="00:23:14.540" end="00:23:15.180" style="1">This patient,</p>
			<p begin="00:23:15.180" end="00:23:17.990" style="1">if you notice on the double contrast study has multiple </p>
			<p begin="00:23:18.310" end="00:23:21.200" style="1">punk Tate and </p>
			<p begin="00:23:21.200" end="00:23:23.230" style="1">linear collections of barium.</p>
			<p begin="00:23:23.270" end="00:23:23.800" style="1">Next slide,</p>
			<p begin="00:23:23.800" end="00:23:25.860" style="1">I think there&apos;s a close up in a different projection.</p>
			<p begin="00:23:27.040" end="00:23:30.040" style="1">Multiple punkt eight and linear collections of barium and </p>
			<p begin="00:23:30.040" end="00:23:32.600" style="1">many of the punk take collections are surrounded </p>
			<p begin="00:23:32.600" end="00:23:33.910" style="1">by nuisances.</p>
			<p begin="00:23:33.910" end="00:23:36.660" style="1">Can we go back to the other slide out and it seems from here.</p>
			<p begin="00:23:36.660" end="00:23:37.770" style="1">It projects a little better.</p>
			<p begin="00:23:38.090" end="00:23:41.010" style="1">Many of these little collections are surrounded by licenses and this </p>
			<p begin="00:23:41.010" end="00:23:43.850" style="1">is a pretty classic radiologic example of </p>
			<p begin="00:23:43.850" end="00:23:46.730" style="1">erosive gastritis with multiple fine </p>
			<p begin="00:23:46.730" end="00:23:49.700" style="1">linear and and dot like superficial ulceration surrounded </p>
			<p begin="00:23:49.700" end="00:23:51.170" style="1">by small halos of oedema.</p>
			<p begin="00:23:51.730" end="00:23:54.670" style="1">And this is a diagnosis that can be made only with </p>
			<p begin="00:23:54.670" end="00:23:57.320" style="1">this technique and with some frequency according to the </p>
			<p begin="00:23:57.320" end="00:23:57.710" style="1">literature.</p>
			<p begin="00:23:57.710" end="00:23:57.960" style="1">Again,</p>
			<p begin="00:23:57.960" end="00:24:00.840" style="1">we don&apos;t see that kind of patient here.</p>
			<p begin="00:24:00.840" end="00:24:01.560" style="1">Very often,</p>
			<p begin="00:24:01.940" end="00:24:04.670" style="1">I should comment at this point that </p>
			<p begin="00:24:05.040" end="00:24:07.600" style="1">these techniques were originally evolved in </p>
			<p begin="00:24:07.600" end="00:24:08.960" style="1">Japan primarily.</p>
			<p begin="00:24:09.340" end="00:24:11.950" style="1">Certainly they were popularized from Japan </p>
			<p begin="00:24:11.960" end="00:24:14.850" style="1">for the earlier diagnosis of focal,</p>
			<p begin="00:24:14.860" end="00:24:17.170" style="1">non invasive carcinomas in that country.</p>
			<p begin="00:24:17.540" end="00:24:20.470" style="1">And judging from the literature and from our own experience here,</p>
			<p begin="00:24:20.470" end="00:24:23.190" style="1">although it may be a little skewed by the type of institution that this </p>
			<p begin="00:24:23.190" end="00:24:23.660" style="1">is,</p>
			<p begin="00:24:24.040" end="00:24:26.590" style="1">we don&apos;t find many early malignancies,</p>
			<p begin="00:24:26.900" end="00:24:29.460" style="1">certainly not add no carcinomas with this technique </p>
			<p begin="00:24:29.590" end="00:24:32.010" style="1">that may relate to the fact that we don&apos;t see early </p>
			<p begin="00:24:32.010" end="00:24:35.010" style="1">patients or that gastric carcinoma is not as common </p>
			<p begin="00:24:35.010" end="00:24:37.520" style="1">a disease here as it is in japan or perhaps </p>
			<p begin="00:24:37.890" end="00:24:40.800" style="1">to some extent the fact that we are not surveying patients in this </p>
			<p begin="00:24:40.800" end="00:24:43.460" style="1">country for this problem as is done in many </p>
			<p begin="00:24:43.460" end="00:24:45.060" style="1">parts of Japan.</p>
			<p begin="00:24:45.440" end="00:24:48.050" style="1">So I think that the yield in gastric </p>
			<p begin="00:24:48.050" end="00:24:50.590" style="1">malignant diseases not nearly going to be as high as it </p>
			<p begin="00:24:50.590" end="00:24:53.450" style="1">is in the orient.</p>
			<p begin="00:24:53.840" end="00:24:54.410" style="1">However,</p>
			<p begin="00:24:54.410" end="00:24:57.180" style="1">there are diagnoses that are made in this country?</p>
			<p begin="00:24:57.190" end="00:24:59.950" style="1">Uh that are coming here that can be made really only with this </p>
			<p begin="00:24:59.950" end="00:25:01.500" style="1">technique and that&apos;s why I stopped here.</p>
			<p begin="00:25:01.500" end="00:25:02.720" style="1">This is such a diagnosis.</p>
			<p begin="00:25:02.720" end="00:25:05.470" style="1">The case of a gi bleeder bleeding from erosive </p>
			<p begin="00:25:05.470" end="00:25:06.300" style="1">gastritis.</p>
			<p begin="00:25:06.670" end="00:25:09.110" style="1">Uh This is going to be a high yield </p>
			<p begin="00:25:09.110" end="00:25:11.730" style="1">diagnosis with this technique uh in the United </p>
			<p begin="00:25:11.730" end="00:25:13.460" style="1">States and north America in general.</p>
			<p begin="00:25:13.540" end="00:25:16.060" style="1">Next line and the next </p>
			<p begin="00:25:18.040" end="00:25:19.170" style="1">a gastric polyp.</p>
			<p begin="00:25:20.640" end="00:25:23.640" style="1">Next line and another </p>
			<p begin="00:25:23.640" end="00:25:26.340" style="1">gastric pile up and we can see her again the network </p>
			<p begin="00:25:26.340" end="00:25:29.050" style="1">pattern the area gastric pattern that you&apos;ll see discussing the </p>
			<p begin="00:25:29.050" end="00:25:30.170" style="1">reports periodically.</p>
			<p begin="00:25:31.940" end="00:25:34.830" style="1">Next line here&apos;s a pretty </p>
			<p begin="00:25:34.830" end="00:25:35.720" style="1">obvious case.</p>
			<p begin="00:25:35.730" end="00:25:38.510" style="1">Uh I don&apos;t think one is going to miss this with any technique </p>
			<p begin="00:25:38.630" end="00:25:40.880" style="1">large sub mucosal mass and other nodule.</p>
			<p begin="00:25:40.880" end="00:25:43.740" style="1">A rude guy representing lymphoma in this patient </p>
			<p begin="00:25:43.740" end="00:25:46.560" style="1">but a very elegant example of the entire extent of </p>
			<p begin="00:25:46.560" end="00:25:48.060" style="1">disease in this patient&apos;s stomach.</p>
			<p begin="00:25:48.740" end="00:25:49.670" style="1">Next line,</p>
			<p begin="00:25:51.340" end="00:25:53.080" style="1">another large ulcerated mass.</p>
			<p begin="00:25:53.080" end="00:25:53.950" style="1">On the lesser curvature.</p>
			<p begin="00:25:53.950" end="00:25:55.450" style="1">This was an adenocarcinoma.</p>
			<p begin="00:25:56.040" end="00:25:56.760" style="1">Next slide </p>
			<p begin="00:25:58.940" end="00:26:01.160" style="1">now we were talking about primary malignancies.</p>
			<p begin="00:26:01.160" end="00:26:03.430" style="1">We have had a yield in about three or four patients </p>
			<p begin="00:26:03.650" end="00:26:06.150" style="1">of one form of malignant disease in the stomach.</p>
			<p begin="00:26:06.150" end="00:26:08.030" style="1">Not diagnosable with conventional techniques.</p>
			<p begin="00:26:08.030" end="00:26:09.120" style="1">And here is such a case.</p>
			<p begin="00:26:09.440" end="00:26:12.390" style="1">This is a single isolated metastatic melanoma </p>
			<p begin="00:26:12.390" end="00:26:15.360" style="1">deposit on the greater curvature of the stomach that was only diagnosed </p>
			<p begin="00:26:15.360" end="00:26:18.070" style="1">on this film with double contrast techniques.</p>
			<p begin="00:26:18.380" end="00:26:21.080" style="1">Next slide and another more </p>
			<p begin="00:26:21.080" end="00:26:21.670" style="1">recent case.</p>
			<p begin="00:26:21.670" end="00:26:24.410" style="1">In this upright view of the fund is there is a small sub mucosal </p>
			<p begin="00:26:24.410" end="00:26:27.350" style="1">mass in this patient with melanoma,</p>
			<p begin="00:26:28.440" end="00:26:30.290" style="1">isolated lesion.</p>
			<p begin="00:26:30.300" end="00:26:32.990" style="1">So we have had yield in this form of malignant </p>
			<p begin="00:26:32.990" end="00:26:35.290" style="1">disease although not primary malignant disease.</p>
			<p begin="00:26:35.290" end="00:26:35.850" style="1">Next line </p>
			<p begin="00:26:38.240" end="00:26:41.240" style="1">okay that finishes discussion of the stomach and I </p>
			<p begin="00:26:41.250" end="00:26:43.550" style="1">have a few brief words now on the duodenum.</p>
			<p begin="00:26:43.940" end="00:26:45.670" style="1">Hi platonic doing ethnography.</p>
			<p begin="00:26:45.670" end="00:26:48.400" style="1">That is the use of a pharmacologic agent to paralyze the </p>
			<p begin="00:26:48.400" end="00:26:51.160" style="1">duodenum and obtain better films of the duodenal </p>
			<p begin="00:26:51.160" end="00:26:53.300" style="1">pancreatic interface has been </p>
			<p begin="00:26:53.310" end="00:26:56.240" style="1">uh pretty popular in this country for about </p>
			<p begin="00:26:56.250" end="00:26:57.840" style="1">10 years or so now.</p>
			<p begin="00:26:58.020" end="00:27:00.990" style="1">And uh air contrast portion of that </p>
			<p begin="00:27:00.990" end="00:27:03.530" style="1">exam is is a routine portion of double </p>
			<p begin="00:27:03.530" end="00:27:06.510" style="1">contrast of high platonic doing </p>
			<p begin="00:27:06.510" end="00:27:06.990" style="1">ethnography.</p>
			<p begin="00:27:06.990" end="00:27:09.900" style="1">And here is an example of a paralyzed duodenum with a nice </p>
			<p begin="00:27:10.340" end="00:27:12.740" style="1">perry ambulatory or perry vegetarian duodenal </p>
			<p begin="00:27:12.740" end="00:27:15.550" style="1">diverticular one can appreciate the very nice mucosal </p>
			<p begin="00:27:15.550" end="00:27:18.420" style="1">pattern here is the longitudinal fold extending down from the </p>
			<p begin="00:27:18.420" end="00:27:19.460" style="1">area of the ambulance.</p>
			<p begin="00:27:19.940" end="00:27:22.800" style="1">Uh So this is certainly a very helpful technique not only </p>
			<p begin="00:27:22.800" end="00:27:25.080" style="1">for the diagnosis of disease and the head of the pancreas,</p>
			<p begin="00:27:25.080" end="00:27:27.150" style="1">but for primary duodenal disease as well,</p>
			<p begin="00:27:27.150" end="00:27:30.030" style="1">it&apos;s gonna be helpful in ulcer disease and occasional </p>
			<p begin="00:27:30.030" end="00:27:31.270" style="1">duodenal tumors as well.</p>
			<p begin="00:27:31.740" end="00:27:34.640" style="1">Next line indications for this </p>
			<p begin="00:27:34.640" end="00:27:36.650" style="1">exam or if a conventional upper G.</p>
			<p begin="00:27:36.650" end="00:27:36.780" style="1">I.</p>
			<p begin="00:27:36.780" end="00:27:39.480" style="1">Series is suspicious for primary duty or </p>
			<p begin="00:27:39.480" end="00:27:40.620" style="1">pancreatic disease.</p>
			<p begin="00:27:40.900" end="00:27:43.510" style="1">And if there is a strong clinical suspicion of </p>
			<p begin="00:27:43.510" end="00:27:46.210" style="1">pancreatic disease despite an apparently normal upper </p>
			<p begin="00:27:46.210" end="00:27:49.020" style="1">gastrointestinal uh series </p>
			<p begin="00:27:49.590" end="00:27:52.300" style="1">technique can be done with a tube or without a tube </p>
			<p begin="00:27:52.300" end="00:27:55.230" style="1">and uh we have done them both ways in the </p>
			<p begin="00:27:55.240" end="00:27:55.770" style="1">department.</p>
			<p begin="00:27:55.770" end="00:27:58.600" style="1">So this is a technique that you can order on patients </p>
			<p begin="00:27:58.600" end="00:28:00.880" style="1">where you fit these indications.</p>
			<p begin="00:28:01.150" end="00:28:03.570" style="1">And very often we will just incorporate it into our </p>
			<p begin="00:28:03.570" end="00:28:06.570" style="1">examination when uh when that </p>
			<p begin="00:28:06.570" end="00:28:08.850" style="1">is necessary to come to a more </p>
			<p begin="00:28:08.850" end="00:28:11.390" style="1">accurate diagnosis.</p>
			<p begin="00:28:11.670" end="00:28:12.270" style="1">Next line,</p>
			<p begin="00:28:14.440" end="00:28:16.710" style="1">there&apos;s an interesting patient we had not long ago.</p>
			<p begin="00:28:16.710" end="00:28:19.640" style="1">This is a patient who had a lot of nice spot films of duodenum </p>
			<p begin="00:28:19.760" end="00:28:22.760" style="1">and had an apparent pad effect or mass along the medial </p>
			<p begin="00:28:22.760" end="00:28:25.670" style="1">contour of that duodenum do deny </p>
			<p begin="00:28:25.670" end="00:28:27.350" style="1">graham was performed next slide,</p>
			<p begin="00:28:29.140" end="00:28:31.850" style="1">which is perfectly normal and shows us that this </p>
			<p begin="00:28:31.870" end="00:28:34.460" style="1">pseudo mass appearance was formed by this </p>
			<p begin="00:28:34.460" end="00:28:37.390" style="1">longitudinal fold extending down from this </p>
			<p begin="00:28:37.390" end="00:28:38.830" style="1">somewhat prominent and pula.</p>
			<p begin="00:28:38.890" end="00:28:41.870" style="1">So sometimes normal anatomical variants in </p>
			<p begin="00:28:41.870" end="00:28:44.600" style="1">the duodenum can be mistaken for </p>
			<p begin="00:28:44.600" end="00:28:47.500" style="1">masses and can be resolved with HIPPA tonic doing </p>
			<p begin="00:28:47.500" end="00:28:48.180" style="1">ethnography.</p>
			<p begin="00:28:48.320" end="00:28:51.320" style="1">Next line and this is an </p>
			<p begin="00:28:51.320" end="00:28:53.820" style="1">example of a carcinoma of the </p>
			<p begin="00:28:53.830" end="00:28:56.460" style="1">excuse me of the duodenum with traction </p>
			<p begin="00:28:56.460" end="00:28:56.840" style="1">changes.</p>
			<p begin="00:28:56.840" end="00:28:57.660" style="1">I hope you can see that.</p>
			<p begin="00:28:57.660" end="00:28:58.810" style="1">I can&apos;t see it too well from here,</p>
			<p begin="00:28:58.810" end="00:29:01.030" style="1">traction changes on the duodenum in this portion.</p>
			<p begin="00:29:01.030" end="00:29:03.550" style="1">So air contrast work is a,</p>
			<p begin="00:29:03.550" end="00:29:03.880" style="1">let&apos;s say,</p>
			<p begin="00:29:03.880" end="00:29:06.490" style="1">a routine part of hip a tonic doing ethnography and </p>
			<p begin="00:29:06.670" end="00:29:09.000" style="1">not infrequently the air contrast films </p>
			<p begin="00:29:09.010" end="00:29:11.540" style="1">uh are the highest yield </p>
			<p begin="00:29:11.540" end="00:29:14.350" style="1">among in the examination performed with a high </p>
			<p begin="00:29:14.350" end="00:29:16.260" style="1">platonic agent of the duodenum.</p>
			<p begin="00:29:16.640" end="00:29:17.170" style="1">Excellent.</p>
			<p begin="00:29:17.640" end="00:29:17.840" style="1">Yeah.</p>
			<p begin="00:29:18.440" end="00:29:18.950" style="1">Next line.</p>
			<p begin="00:29:20.440" end="00:29:21.960" style="1">Well all that&apos;s been good.</p>
			<p begin="00:29:21.960" end="00:29:23.800" style="1">And we&apos;ve talked about the upper gastrointestinal tract.</p>
			<p begin="00:29:23.800" end="00:29:26.630" style="1">But now we really come to the money and that&apos;s the colon at </p>
			<p begin="00:29:26.630" end="00:29:29.170" style="1">least the money for neo plastic </p>
			<p begin="00:29:29.540" end="00:29:30.350" style="1">disease.</p>
			<p begin="00:29:31.750" end="00:29:34.270" style="1">This is really where I think we can most help </p>
			<p begin="00:29:34.640" end="00:29:37.520" style="1">our patients here is a place </p>
			<p begin="00:29:37.520" end="00:29:39.470" style="1">where when we say a small tumor,</p>
			<p begin="00:29:39.630" end="00:29:42.380" style="1">we almost talks anonymously with an early tumor.</p>
			<p begin="00:29:42.530" end="00:29:45.170" style="1">Unlike other anatomical parts in the gastrointestinal </p>
			<p begin="00:29:45.170" end="00:29:47.700" style="1">track in other areas of the </p>
			<p begin="00:29:47.720" end="00:29:48.900" style="1">body here.</p>
			<p begin="00:29:48.900" end="00:29:51.240" style="1">A small tumor is means </p>
			<p begin="00:29:51.250" end="00:29:52.380" style="1">early tumor.</p>
			<p begin="00:29:52.380" end="00:29:55.260" style="1">And we want to be able to make the diagnosis of small uh </p>
			<p begin="00:29:55.440" end="00:29:56.920" style="1">colonic tumors.</p>
			<p begin="00:29:56.920" end="00:29:59.900" style="1">And let&apos;s talk about the colon preparation.</p>
			<p begin="00:29:59.900" end="00:30:00.890" style="1">And let me say to you,</p>
			<p begin="00:30:00.890" end="00:30:02.810" style="1">although you know this,</p>
			<p begin="00:30:02.810" end="00:30:03.360" style="1">you know,</p>
			<p begin="00:30:03.740" end="00:30:06.260" style="1">this is the most important part of the examination.</p>
			<p begin="00:30:06.260" end="00:30:07.160" style="1">This is the whole thing.</p>
			<p begin="00:30:07.160" end="00:30:07.770" style="1">In fact,</p>
			<p begin="00:30:07.780" end="00:30:10.690" style="1">the exam is not very difficult and it </p>
			<p begin="00:30:10.690" end="00:30:12.800" style="1">doesn&apos;t require particularly sophisticated equipment,</p>
			<p begin="00:30:12.810" end="00:30:15.600" style="1">but you do have to have the colon prepared in </p>
			<p begin="00:30:15.600" end="00:30:16.110" style="1">some ways,</p>
			<p begin="00:30:16.110" end="00:30:16.980" style="1">colonoscopy,</p>
			<p begin="00:30:16.980" end="00:30:18.440" style="1">which we&apos;ll talk about in a few minutes,</p>
			<p begin="00:30:18.450" end="00:30:21.420" style="1">which has come in some centers to rival </p>
			<p begin="00:30:21.430" end="00:30:22.510" style="1">uh,</p>
			<p begin="00:30:22.520" end="00:30:25.480" style="1">barium studies of the colon really has done us a little </p>
			<p begin="00:30:25.480" end="00:30:27.960" style="1">bit of help there because </p>
			<p begin="00:30:27.970" end="00:30:30.490" style="1">clinicians now at least people are doing colonoscopy </p>
			<p begin="00:30:30.490" end="00:30:33.380" style="1">realized that when we were talking about all the filling </p>
			<p begin="00:30:33.380" end="00:30:35.950" style="1">defects in the colon really can be a problem making a </p>
			<p begin="00:30:35.950" end="00:30:36.610" style="1">diagnosis.</p>
			<p begin="00:30:36.610" end="00:30:38.030" style="1">So they colonize space,</p>
			<p begin="00:30:38.030" end="00:30:38.600" style="1">appreciate,</p>
			<p begin="00:30:38.610" end="00:30:41.170" style="1">appreciate now the value of a clean </p>
			<p begin="00:30:41.180" end="00:30:41.620" style="1">colon,</p>
			<p begin="00:30:41.620" end="00:30:42.600" style="1">the entire colon.</p>
			<p begin="00:30:43.240" end="00:30:43.940" style="1">Um,</p>
			<p begin="00:30:43.950" end="00:30:46.590" style="1">please please please please </p>
			<p begin="00:30:46.590" end="00:30:49.140" style="1">please encourage your patients to take the </p>
			<p begin="00:30:49.140" end="00:30:49.770" style="1">preparation.</p>
			<p begin="00:30:50.340" end="00:30:52.460" style="1">Don&apos;t tell him our it&apos;s okay if you skip something,</p>
			<p begin="00:30:52.940" end="00:30:53.300" style="1">you know,</p>
			<p begin="00:30:53.300" end="00:30:56.110" style="1">encourage them to take the preparation and we&apos;ll discuss what </p>
			<p begin="00:30:56.110" end="00:30:57.030" style="1">we use here.</p>
			<p begin="00:30:57.030" end="00:30:57.180" style="1">You know,</p>
			<p begin="00:30:57.180" end="00:31:00.010" style="1">the preparation is I&apos;m not saying it&apos;s the most pleasant thing to get up </p>
			<p begin="00:31:00.010" end="00:31:01.900" style="1">in the morning and go and have a very minimal,</p>
			<p begin="00:31:01.900" end="00:31:02.520" style="1">but you know,</p>
			<p begin="00:31:02.530" end="00:31:03.450" style="1">it has to be done,</p>
			<p begin="00:31:03.450" end="00:31:03.670" style="1">you know,</p>
			<p begin="00:31:03.670" end="00:31:06.260" style="1">it has to be done and we want to do it well and </p>
			<p begin="00:31:06.270" end="00:31:07.340" style="1">help the patient.</p>
			<p begin="00:31:07.350" end="00:31:10.240" style="1">So please encourage your patients to </p>
			<p begin="00:31:10.240" end="00:31:11.310" style="1">take the preparation.</p>
			<p begin="00:31:11.740" end="00:31:12.370" style="1">Okay,</p>
			<p begin="00:31:12.380" end="00:31:13.270" style="1">that&apos;s number one.</p>
			<p begin="00:31:13.840" end="00:31:14.770" style="1">Number two.</p>
			<p begin="00:31:15.140" end="00:31:18.050" style="1">Um four </p>
			<p begin="00:31:18.440" end="00:31:20.940" style="1">patients who are in patients in this hospital,</p>
			<p begin="00:31:20.960" end="00:31:23.760" style="1">we are unable to write for routine,</p>
			<p begin="00:31:23.760" end="00:31:25.020" style="1">very minimal preparation.</p>
			<p begin="00:31:25.140" end="00:31:26.950" style="1">The orders have to be written out.</p>
			<p begin="00:31:27.240" end="00:31:27.430" style="1">Well,</p>
			<p begin="00:31:27.430" end="00:31:30.120" style="1">there is in every nurse&apos;s station at this hospital,</p>
			<p begin="00:31:30.120" end="00:31:31.690" style="1">we&apos;ve checked any number of times,</p>
			<p begin="00:31:32.230" end="00:31:33.330" style="1">at least one copy.</p>
			<p begin="00:31:33.330" end="00:31:36.270" style="1">If not more of our routine barium enema preparation,</p>
			<p begin="00:31:36.640" end="00:31:37.450" style="1">follow it,</p>
			<p begin="00:31:37.940" end="00:31:40.110" style="1">sit down with it and write it into the chart.</p>
			<p begin="00:31:40.120" end="00:31:41.510" style="1">I don&apos;t say it&apos;s a pleasant task,</p>
			<p begin="00:31:41.520" end="00:31:42.650" style="1">but it has to be done.</p>
			<p begin="00:31:42.790" end="00:31:44.720" style="1">So follow it on your impatience.</p>
			<p begin="00:31:44.980" end="00:31:47.840" style="1">If there&apos;s any question as to why a patient can&apos;t take a preparation,</p>
			<p begin="00:31:48.040" end="00:31:48.870" style="1">You can call us,</p>
			<p begin="00:31:48.870" end="00:31:49.130" style="1">you know,</p>
			<p begin="00:31:49.130" end="00:31:51.680" style="1">you can call us the department and we can discuss it and we&apos;ll </p>
			<p begin="00:31:51.680" end="00:31:53.010" style="1">modify it if necessary,</p>
			<p begin="00:31:53.010" end="00:31:55.800" style="1">but please write for our entire preparation.</p>
			<p begin="00:31:55.800" end="00:31:57.670" style="1">So we don&apos;t have a compromised exam.</p>
			<p begin="00:31:58.240" end="00:31:59.120" style="1">Let me tell you that.</p>
			<p begin="00:31:59.120" end="00:32:01.820" style="1">We will not hesitate in the radiology department to </p>
			<p begin="00:32:01.820" end="00:32:03.670" style="1">cancel the patient&apos;s examination.</p>
			<p begin="00:32:04.040" end="00:32:06.890" style="1">Uh If he has not taken a preparation or it </p>
			<p begin="00:32:06.890" end="00:32:08.960" style="1">hasn&apos;t been ordered for him as an inpatient.</p>
			<p begin="00:32:08.960" end="00:32:10.140" style="1">We do our best to,</p>
			<p begin="00:32:10.250" end="00:32:10.580" style="1">you know,</p>
			<p begin="00:32:10.580" end="00:32:12.070" style="1">to accomplish the examination.</p>
			<p begin="00:32:12.070" end="00:32:13.280" style="1">We will will go so far,</p>
			<p begin="00:32:13.280" end="00:32:15.470" style="1">we&apos;ll give multiple enemies in our own department.</p>
			<p begin="00:32:15.560" end="00:32:16.260" style="1">But you know,</p>
			<p begin="00:32:16.260" end="00:32:17.540" style="1">we need cooperation.</p>
			<p begin="00:32:17.540" end="00:32:20.360" style="1">We don&apos;t feel we&apos;re going to do the patients a favor or you a </p>
			<p begin="00:32:20.360" end="00:32:23.150" style="1">favor if we do an inadequate examination and MS </p>
			<p begin="00:32:23.150" end="00:32:25.790" style="1">a potentially curable colon lesion.</p>
			<p begin="00:32:26.240" end="00:32:28.960" style="1">And another point I want to make before we look at some </p>
			<p begin="00:32:28.970" end="00:32:31.970" style="1">cases is that many times you may order a barium </p>
			<p begin="00:32:31.970" end="00:32:34.390" style="1">enema and we&apos;ll do an air </p>
			<p begin="00:32:34.390" end="00:32:36.960" style="1">contrast or occasionally vice versa.</p>
			<p begin="00:32:37.320" end="00:32:39.810" style="1">Please give us adequate history on the </p>
			<p begin="00:32:39.810" end="00:32:42.720" style="1">requisition so that we can make a reliable judgment as to </p>
			<p begin="00:32:42.720" end="00:32:45.210" style="1">what kind of examination the patient needs.</p>
			<p begin="00:32:45.210" end="00:32:47.900" style="1">There are certain indications that we follow that I&apos;m going to show you in a few </p>
			<p begin="00:32:47.900" end="00:32:48.350" style="1">moments.</p>
			<p begin="00:32:48.740" end="00:32:51.180" style="1">And uh if we don&apos;t have reliable history </p>
			<p begin="00:32:51.350" end="00:32:53.930" style="1">written down there or we can&apos;t communicate with the patient,</p>
			<p begin="00:32:53.930" end="00:32:56.850" style="1">it&apos;s difficult for us to make a good decision about what </p>
			<p begin="00:32:56.850" end="00:32:58.780" style="1">examination is best for that patient.</p>
			<p begin="00:32:58.890" end="00:33:01.720" style="1">So uh please give us adequate history </p>
			<p begin="00:33:01.720" end="00:33:03.110" style="1">so that we can make the judgment.</p>
			<p begin="00:33:03.280" end="00:33:06.230" style="1">But you will find times when a conventional enemy is ordered </p>
			<p begin="00:33:06.230" end="00:33:09.170" style="1">or just it&apos;s written barium enema and we do in air contrast and </p>
			<p begin="00:33:09.170" end="00:33:10.310" style="1">occasionally vice versa.</p>
			<p begin="00:33:10.310" end="00:33:12.550" style="1">But we do what we think is most indicated to </p>
			<p begin="00:33:12.940" end="00:33:15.540" style="1">make an accurate diagnosis in that patient </p>
			<p begin="00:33:15.560" end="00:33:18.500" style="1">after we&apos;ve talked to them and seeing the history </p>
			<p begin="00:33:18.500" end="00:33:19.060" style="1">requisition.</p>
			<p begin="00:33:19.060" end="00:33:22.060" style="1">So this is the colon preparation that&apos;s used in this hospital.</p>
			<p begin="00:33:22.640" end="00:33:25.610" style="1">We do our upper jeez first and we have done that for </p>
			<p begin="00:33:25.610" end="00:33:27.080" style="1">the last several years.</p>
			<p begin="00:33:27.080" end="00:33:28.250" style="1">And here is the rationale,</p>
			<p begin="00:33:28.250" end="00:33:30.790" style="1">I&apos;ve had a lot of phone calls on this if a </p>
			<p begin="00:33:30.790" end="00:33:33.490" style="1">patient is going to have both exams that is an </p>
			<p begin="00:33:33.500" end="00:33:36.010" style="1">upper gastrointestinal series and a barium </p>
			<p begin="00:33:36.010" end="00:33:36.580" style="1">enema.</p>
			<p begin="00:33:36.690" end="00:33:38.420" style="1">We do the upper gi first,</p>
			<p begin="00:33:38.420" end="00:33:40.290" style="1">our scheduling people know to do that.</p>
			<p begin="00:33:40.300" end="00:33:42.960" style="1">And the reason we do that examination first is </p>
			<p begin="00:33:43.340" end="00:33:46.100" style="1">so that we use the berry um that they&apos;ve ingested as a </p>
			<p begin="00:33:46.100" end="00:33:48.560" style="1">marker to tell us if the colon is clean.</p>
			<p begin="00:33:48.940" end="00:33:51.930" style="1">That is to say if a patient has an upper gastrointestinal </p>
			<p begin="00:33:51.930" end="00:33:54.800" style="1">series on monday of a given week and </p>
			<p begin="00:33:54.800" end="00:33:57.450" style="1">on Tuesday they begin their colon preparation </p>
			<p begin="00:33:57.460" end="00:33:58.870" style="1">on Wednesday morning.</p>
			<p begin="00:33:58.870" end="00:34:01.660" style="1">If there is any significant amount of barium retaining their </p>
			<p begin="00:34:01.660" end="00:34:02.170" style="1">colon,</p>
			<p begin="00:34:02.290" end="00:34:05.240" style="1">we have an opaque barium marker to tell us that </p>
			<p begin="00:34:05.240" end="00:34:06.560" style="1">the colon is not clean.</p>
			<p begin="00:34:06.940" end="00:34:09.930" style="1">That is the rationale for us doing a upper gastrointestinal </p>
			<p begin="00:34:09.930" end="00:34:12.790" style="1">series first in most routine patents obviously if there </p>
			<p begin="00:34:12.790" end="00:34:14.430" style="1">is a suspicion of colon obstruction,</p>
			<p begin="00:34:14.430" end="00:34:14.980" style="1">we don&apos;t,</p>
			<p begin="00:34:15.310" end="00:34:18.060" style="1">but in the routine patient that&apos;s being worked up for </p>
			<p begin="00:34:18.060" end="00:34:19.260" style="1">bleeding or whatever.</p>
			<p begin="00:34:19.510" end="00:34:21.760" style="1">Upper gastrointestinal series is done first.</p>
			<p begin="00:34:22.540" end="00:34:25.490" style="1">It&apos;s basically an 18 hour preparation that begins </p>
			<p begin="00:34:25.750" end="00:34:28.500" style="1">at noon the previous day and it consists of </p>
			<p begin="00:34:28.500" end="00:34:29.210" style="1">hydration.</p>
			<p begin="00:34:29.230" end="00:34:31.080" style="1">You got to drink a lot of water juice,</p>
			<p begin="00:34:31.540" end="00:34:34.340" style="1">a minimal low residue diet at eight </p>
			<p begin="00:34:34.340" end="00:34:36.850" style="1">p.m. The patient takes magnesium citrate </p>
			<p begin="00:34:37.540" end="00:34:38.380" style="1">at 10 PM.</p>
			<p begin="00:34:38.380" end="00:34:41.220" style="1">Doug relax pills and the morning of the examination,</p>
			<p begin="00:34:41.290" end="00:34:42.850" style="1">a dull colak suppository.</p>
			<p begin="00:34:42.930" end="00:34:45.740" style="1">Probably not the best thing to have to do in life but you know,</p>
			<p begin="00:34:45.740" end="00:34:48.060" style="1">it&apos;s an important preparation and with this preparation </p>
			<p begin="00:34:48.540" end="00:34:50.030" style="1">we can get most Coghlan&apos;s clean.</p>
			<p begin="00:34:50.030" end="00:34:52.600" style="1">Occasionally it takes a second day in patients who are particularly not </p>
			<p begin="00:34:52.600" end="00:34:53.360" style="1">ambulatory.</p>
			<p begin="00:34:53.740" end="00:34:56.540" style="1">We do have uh facility and we&apos;ll have </p>
			<p begin="00:34:56.540" end="00:34:59.270" style="1">further facility I guess in the new department dr </p>
			<p begin="00:34:59.280" end="00:35:02.080" style="1">Dodd as uh designed for a </p>
			<p begin="00:35:02.090" end="00:35:04.990" style="1">uh enema to be given to the patient uh </p>
			<p begin="00:35:05.000" end="00:35:07.470" style="1">if possible and we&apos;ll give those in our </p>
			<p begin="00:35:07.470" end="00:35:08.020" style="1">department,</p>
			<p begin="00:35:08.020" end="00:35:10.190" style="1">I must say relating to air contrast work.</p>
			<p begin="00:35:10.190" end="00:35:13.010" style="1">I personally don&apos;t like to do animals prior to air </p>
			<p begin="00:35:13.010" end="00:35:15.600" style="1">contrast work because most patients don&apos;t evacuate </p>
			<p begin="00:35:15.940" end="00:35:18.520" style="1">of the water and can affect the coating of the burial.</p>
			<p begin="00:35:18.520" end="00:35:20.070" style="1">But others do do this routinely.</p>
			<p begin="00:35:20.070" end="00:35:22.250" style="1">But we rely primarily on this preparation.</p>
			<p begin="00:35:22.250" end="00:35:24.810" style="1">So please make sure as much as you </p>
			<p begin="00:35:24.810" end="00:35:27.800" style="1">can that the Coghlan&apos;s of your patients are </p>
			<p begin="00:35:27.800" end="00:35:30.750" style="1">prepared so that we don&apos;t do them injustice and make an inaccurate </p>
			<p begin="00:35:30.750" end="00:35:31.510" style="1">diagnosis.</p>
			<p begin="00:35:31.630" end="00:35:32.160" style="1">Excellent </p>
			<p begin="00:35:34.640" end="00:35:35.960" style="1">patients done prone,</p>
			<p begin="00:35:36.340" end="00:35:38.350" style="1">we run bury him into part of the colon,</p>
			<p begin="00:35:39.040" end="00:35:41.120" style="1">shake the berry um into the rest of the colon,</p>
			<p begin="00:35:41.130" end="00:35:42.660" style="1">drained the rectum and put the area.</p>
			<p begin="00:35:42.660" end="00:35:45.600" style="1">It&apos;s a very simple technique that can be be </p>
			<p begin="00:35:45.600" end="00:35:48.240" style="1">done can be done in any radiology department and then a number of </p>
			<p begin="00:35:48.240" end="00:35:50.670" style="1">radiographs are obtained both spot films taken that </p>
			<p begin="00:35:51.040" end="00:35:53.670" style="1">Flora&apos;s copy and what we call overhead </p>
			<p begin="00:35:53.670" end="00:35:56.120" style="1">radiographs taken by the uh technical </p>
			<p begin="00:35:56.130" end="00:35:56.710" style="1">people.</p>
			<p begin="00:35:56.720" end="00:35:57.250" style="1">Again,</p>
			<p begin="00:35:57.250" end="00:35:58.860" style="1">this idea of low killer voltage,</p>
			<p begin="00:35:58.870" end="00:36:01.540" style="1">which means higher contrast on the pictures.</p>
			<p begin="00:36:01.930" end="00:36:02.550" style="1">Next line,</p>
			<p begin="00:36:04.730" end="00:36:07.670" style="1">these are commercial burying preparations that we are now using for a </p>
			<p begin="00:36:07.670" end="00:36:07.990" style="1">time.</p>
			<p begin="00:36:07.990" end="00:36:09.940" style="1">We were mixing several commercial bearing preparations.</p>
			<p begin="00:36:09.940" end="00:36:12.890" style="1">But now there are good commercial products available for all of </p>
			<p begin="00:36:12.890" end="00:36:14.020" style="1">these techniques to use.</p>
			<p begin="00:36:14.300" end="00:36:17.300" style="1">This comes as a liquid and we just poured into the bag and put that into the </p>
			<p begin="00:36:17.300" end="00:36:18.050" style="1">patient&apos;s colon.</p>
			<p begin="00:36:18.140" end="00:36:20.910" style="1">Next this is the </p>
			<p begin="00:36:20.910" end="00:36:21.430" style="1">enema tip.</p>
			<p begin="00:36:21.430" end="00:36:23.820" style="1">It&apos;s a soft plastic enema tip and </p>
			<p begin="00:36:23.820" end="00:36:26.450" style="1">piggybacked into the enema tip is a fairly </p>
			<p begin="00:36:26.450" end="00:36:27.350" style="1">large bore needle,</p>
			<p begin="00:36:27.350" end="00:36:30.310" style="1">like a 16 gauge needle that&apos;s tips just right in through the enema </p>
			<p begin="00:36:30.310" end="00:36:31.320" style="1">tip into the aluminum,</p>
			<p begin="00:36:31.650" end="00:36:31.990" style="1">aluminum,</p>
			<p begin="00:36:31.990" end="00:36:34.860" style="1">the enemy tip and stigma nanometer bulb introduces the </p>
			<p begin="00:36:34.860" end="00:36:35.890" style="1">air when we&apos;re ready for that.</p>
			<p begin="00:36:35.890" end="00:36:38.590" style="1">So the barium goes through here and the air through here.</p>
			<p begin="00:36:38.600" end="00:36:39.750" style="1">Very easy setup.</p>
			<p begin="00:36:39.760" end="00:36:40.350" style="1">Next line,</p>
			<p begin="00:36:42.330" end="00:36:44.990" style="1">so this is about ready to begin the bag of </p>
			<p begin="00:36:44.990" end="00:36:47.910" style="1">barium with large bore tubing so that this moderately viscous </p>
			<p begin="00:36:47.910" end="00:36:50.800" style="1">barium will flow through and patients began prone.</p>
			<p begin="00:36:50.800" end="00:36:53.740" style="1">Next line we said that barium does </p>
			<p begin="00:36:53.740" end="00:36:55.960" style="1">have to be squeezed in next line </p>
			<p begin="00:36:57.810" end="00:37:00.620" style="1">and the Baron&apos;s run so that the colon is approximately </p>
			<p begin="00:37:00.620" end="00:37:01.540" style="1">halfway field.</p>
			<p begin="00:37:01.930" end="00:37:04.770" style="1">Next line and the patients turned on the </p>
			<p begin="00:37:04.770" end="00:37:07.680" style="1">right side and shaking a little bit and usually this will advance the barium into </p>
			<p begin="00:37:07.680" end="00:37:10.400" style="1">the right colon and we&apos;ll go ahead and drain the rectum.</p>
			<p begin="00:37:10.400" end="00:37:13.140" style="1">Next slide after the rectums </p>
			<p begin="00:37:13.140" end="00:37:16.070" style="1">drain will instill the air we put as much air in as </p>
			<p begin="00:37:16.070" end="00:37:18.810" style="1">the patient can reasonably and comfortably tolerate or </p>
			<p begin="00:37:18.810" end="00:37:21.680" style="1">until reflux into the small bowel occurs and </p>
			<p begin="00:37:21.680" end="00:37:24.530" style="1">then we begin to take spot films at that point </p>
			<p begin="00:37:24.530" end="00:37:26.450" style="1">we&apos;ll take spot films of the rectum.</p>
			<p begin="00:37:26.650" end="00:37:27.250" style="1">Next line.</p>
			<p begin="00:37:28.830" end="00:37:30.750" style="1">Let&apos;s take spot films of the fletchers.</p>
			<p begin="00:37:31.290" end="00:37:32.680" style="1">These are done in the upright position,</p>
			<p begin="00:37:32.680" end="00:37:33.290" style="1">many of them.</p>
			<p begin="00:37:33.700" end="00:37:34.350" style="1">Next live </p>
			<p begin="00:37:36.630" end="00:37:37.640" style="1">spot films of the Sikh.</p>
			<p begin="00:37:37.640" end="00:37:40.600" style="1">Um There are certain anatomical areas in the colon that we spot in </p>
			<p begin="00:37:40.600" end="00:37:42.450" style="1">various positions.</p>
			<p begin="00:37:42.830" end="00:37:45.570" style="1">Next line and then large </p>
			<p begin="00:37:45.580" end="00:37:48.240" style="1">overhead films are obtained by the technician.</p>
			<p begin="00:37:48.240" end="00:37:49.280" style="1">Supine films.</p>
			<p begin="00:37:49.280" end="00:37:49.850" style="1">Next line,</p>
			<p begin="00:37:52.630" end="00:37:53.450" style="1">upright films.</p>
			<p begin="00:37:53.450" end="00:37:53.950" style="1">Again,</p>
			<p begin="00:37:55.330" end="00:37:58.090" style="1">these are particularly helpful these upright films and to cuBA to </p>
			<p begin="00:37:58.090" end="00:38:01.080" style="1">films that I&apos;m gonna show you particularly helpful because if there is a </p>
			<p begin="00:38:01.080" end="00:38:03.980" style="1">small amount of fecal residue remaining in the colon,</p>
			<p begin="00:38:04.240" end="00:38:04.940" style="1">if it&apos;s free,</p>
			<p begin="00:38:04.950" end="00:38:07.940" style="1">freely moving and not attach the wall with these upright </p>
			<p begin="00:38:07.940" end="00:38:10.830" style="1">films that fecal material will fall into the Bering land.</p>
			<p begin="00:38:10.830" end="00:38:13.370" style="1">We can resolve whether an area is normal or </p>
			<p begin="00:38:13.370" end="00:38:13.850" style="1">abnormal.</p>
			<p begin="00:38:13.850" end="00:38:15.490" style="1">With these techniques.</p>
			<p begin="00:38:15.500" end="00:38:18.140" style="1">Next line and this to cuBA&apos;s </p>
			<p begin="00:38:18.140" end="00:38:20.960" style="1">position that is the patient laying on his side and </p>
			<p begin="00:38:20.960" end="00:38:23.750" style="1">the x ray beam directed horizontally at the </p>
			<p begin="00:38:23.750" end="00:38:26.710" style="1">abdomen patient in this case was laying on her patients right </p>
			<p begin="00:38:26.710" end="00:38:27.240" style="1">side.</p>
			<p begin="00:38:27.820" end="00:38:28.450" style="1">Next line.</p>
			<p begin="00:38:31.620" end="00:38:33.840" style="1">Just a word about colonoscopy.</p>
			<p begin="00:38:34.420" end="00:38:35.790" style="1">Uh There&apos;s been,</p>
			<p begin="00:38:35.790" end="00:38:38.270" style="1">I think in the medical and surgical literature in the </p>
			<p begin="00:38:38.270" end="00:38:39.570" style="1">last few years,</p>
			<p begin="00:38:39.570" end="00:38:42.480" style="1">a fair amount of competition between </p>
			<p begin="00:38:42.490" end="00:38:45.480" style="1">radiographic examinations of the colon and </p>
			<p begin="00:38:45.490" end="00:38:46.450" style="1">colonoscopy.</p>
			<p begin="00:38:47.020" end="00:38:49.840" style="1">Most of these have been written by uh </p>
			<p begin="00:38:49.850" end="00:38:51.360" style="1">gastro neurologists and surgeons,</p>
			<p begin="00:38:51.360" end="00:38:54.240" style="1">particularly one group in new york and they have kind of </p>
			<p begin="00:38:54.240" end="00:38:56.250" style="1">condemned the barium enema examination.</p>
			<p begin="00:38:57.520" end="00:38:57.910" style="1">Well,</p>
			<p begin="00:38:57.910" end="00:39:00.910" style="1">I think that dr nelson agrees here I </p>
			<p begin="00:39:00.910" end="00:39:03.430" style="1">think and probably this is the appropriate,</p>
			<p begin="00:39:03.970" end="00:39:06.950" style="1">the appropriate ah </p>
			<p begin="00:39:07.720" end="00:39:10.210" style="1">point to make on it is that they are complementary exams.</p>
			<p begin="00:39:10.210" end="00:39:12.830" style="1">That&apos;s kind of almost a trite statement about so many things.</p>
			<p begin="00:39:12.830" end="00:39:14.100" style="1">But I think in this case is true.</p>
			<p begin="00:39:14.100" end="00:39:16.960" style="1">There are some things that we can do that colonoscopy can </p>
			<p begin="00:39:16.960" end="00:39:17.400" style="1">do.</p>
			<p begin="00:39:17.410" end="00:39:18.180" style="1">For example,</p>
			<p begin="00:39:18.180" end="00:39:20.510" style="1">colonoscopies can&apos;t get to the seek them every time.</p>
			<p begin="00:39:20.510" end="00:39:23.460" style="1">And we always can if there&apos;s an obstructing lesion of </p>
			<p begin="00:39:23.460" end="00:39:24.880" style="1">colonoscopies can&apos;t get by it.</p>
			<p begin="00:39:24.880" end="00:39:27.620" style="1">And we usually can to see if there are other lesions in the </p>
			<p begin="00:39:27.620" end="00:39:28.040" style="1">colon.</p>
			<p begin="00:39:28.120" end="00:39:30.750" style="1">And there are things that colonoscopy can do </p>
			<p begin="00:39:30.760" end="00:39:33.700" style="1">or detect that we can&apos;t detect not </p>
			<p begin="00:39:33.700" end="00:39:36.340" style="1">to mention the therapeutic applications </p>
			<p begin="00:39:36.340" end="00:39:38.070" style="1">of uh colonoscopy.</p>
			<p begin="00:39:38.070" end="00:39:40.840" style="1">So I think they are complementary techniques </p>
			<p begin="00:39:41.220" end="00:39:43.280" style="1">and uh should be considered.</p>
			<p begin="00:39:43.290" end="00:39:43.960" style="1">So,</p>
			<p begin="00:39:44.120" end="00:39:46.200" style="1">certainly from a on a screening basis.</p>
			<p begin="00:39:46.210" end="00:39:47.040" style="1">Uh you know,</p>
			<p begin="00:39:47.050" end="00:39:49.770" style="1">the time and money involved in doing screening,</p>
			<p begin="00:39:49.770" end="00:39:50.600" style="1">colonoscopy is,</p>
			<p begin="00:39:50.610" end="00:39:51.010" style="1">you know,</p>
			<p begin="00:39:51.020" end="00:39:53.470" style="1">be virtually impossible when in comparison to </p>
			<p begin="00:39:53.480" end="00:39:54.730" style="1">uh barium study.</p>
			<p begin="00:39:54.730" end="00:39:54.880" style="1">So,</p>
			<p begin="00:39:54.880" end="00:39:57.380" style="1">the barium barium enema examination,</p>
			<p begin="00:39:57.380" end="00:40:00.140" style="1">as has been said by a number of </p>
			<p begin="00:40:00.140" end="00:40:00.420" style="1">people.</p>
			<p begin="00:40:00.430" end="00:40:01.390" style="1">It&apos;s not a bad example,</p>
			<p begin="00:40:01.390" end="00:40:02.840" style="1">a very fine examination.</p>
			<p begin="00:40:02.840" end="00:40:04.250" style="1">It&apos;s just not always done well.</p>
			<p begin="00:40:04.250" end="00:40:07.150" style="1">And part of that is our own fault perhaps is the worst </p>
			<p begin="00:40:07.150" end="00:40:09.690" style="1">radiologic examination performed in the United States,</p>
			<p begin="00:40:10.110" end="00:40:12.490" style="1">but we take responsibility for that.</p>
			<p begin="00:40:12.490" end="00:40:15.060" style="1">And uh but you need to take some responsibility too and </p>
			<p begin="00:40:15.060" end="00:40:17.460" style="1">ensuring as much as you can that your patients </p>
			<p begin="00:40:17.800" end="00:40:20.440" style="1">do take the colon preparation and that their Coghlan&apos;s </p>
			<p begin="00:40:20.440" end="00:40:23.330" style="1">are clean next line.</p>
			<p begin="00:40:25.010" end="00:40:27.920" style="1">So some examples of uh of the colon here is </p>
			<p begin="00:40:27.920" end="00:40:30.920" style="1">a classic podunk related polyp in this patient&apos;s </p>
			<p begin="00:40:30.920" end="00:40:33.630" style="1">descending colon next line.</p>
			<p begin="00:40:38.110" end="00:40:38.310" style="1">Yeah.</p>
			<p begin="00:40:41.910" end="00:40:42.650" style="1">And here,</p>
			<p begin="00:40:42.970" end="00:40:45.330" style="1">seeing this on fox is a cecil polyp.</p>
			<p begin="00:40:47.710" end="00:40:48.430" style="1">Next line </p>
			<p begin="00:40:50.810" end="00:40:52.160" style="1">along the right colon here,</p>
			<p begin="00:40:52.160" end="00:40:54.950" style="1">I hope you can see them are a </p>
			<p begin="00:40:54.950" end="00:40:56.530" style="1">number of small polyps.</p>
			<p begin="00:40:59.110" end="00:41:01.820" style="1">We will routinely find little polyps or </p>
			<p begin="00:41:01.820" end="00:41:04.590" style="1">Palepoi expressions is 123 millimeters in </p>
			<p begin="00:41:04.590" end="00:41:07.520" style="1">size when we have a good clean colon.</p>
			<p begin="00:41:07.520" end="00:41:09.350" style="1">And are studying patients very often,</p>
			<p begin="00:41:09.350" end="00:41:12.020" style="1">they&apos;re not symptomatic in regard to </p>
			<p begin="00:41:12.710" end="00:41:15.410" style="1">bleeding or what one would expect from </p>
			<p begin="00:41:15.410" end="00:41:15.830" style="1">polyps.</p>
			<p begin="00:41:15.830" end="00:41:18.710" style="1">And sometimes we don&apos;t really know what to do or say about little polyps like </p>
			<p begin="00:41:18.710" end="00:41:18.900" style="1">this,</p>
			<p begin="00:41:18.900" end="00:41:21.520" style="1">but we will document them and put them into the patients </p>
			<p begin="00:41:22.210" end="00:41:22.900" style="1">record.</p>
			<p begin="00:41:22.900" end="00:41:24.390" style="1">So that&apos;s certainly at a later time.</p>
			<p begin="00:41:24.390" end="00:41:26.810" style="1">If the patient is re examined or become symptomatic,</p>
			<p begin="00:41:26.840" end="00:41:29.700" style="1">one can direct his attention to that area.</p>
			<p begin="00:41:29.730" end="00:41:31.780" style="1">But fairly routinely one will follow.</p>
			<p begin="00:41:31.790" end="00:41:34.730" style="1">One will discover small 1 to 3 </p>
			<p begin="00:41:34.730" end="00:41:36.530" style="1">millimeter polyps in the colon.</p>
			<p begin="00:41:36.710" end="00:41:37.330" style="1">Next line,</p>
			<p begin="00:41:39.310" end="00:41:42.140" style="1">typical annular apple core carcinoma of </p>
			<p begin="00:41:42.140" end="00:41:44.880" style="1">the distal sigmoid or rectal sigmoid </p>
			<p begin="00:41:44.880" end="00:41:45.350" style="1">colon.</p>
			<p begin="00:41:45.410" end="00:41:46.030" style="1">Next line </p>
			<p begin="00:41:48.710" end="00:41:51.650" style="1">here are the indications that we use in this department and are </p>
			<p begin="00:41:51.650" end="00:41:54.530" style="1">generally used by people who advocate um </p>
			<p begin="00:41:55.110" end="00:41:56.860" style="1">Double contrast examination of the colon.</p>
			<p begin="00:41:56.860" end="00:41:59.650" style="1">Certainly rectal bleeding is an indication of the classic </p>
			<p begin="00:41:59.650" end="00:42:01.920" style="1">indication for air contrast colon examinations.</p>
			<p begin="00:42:02.300" end="00:42:03.320" style="1">Also other symptoms,</p>
			<p begin="00:42:03.320" end="00:42:04.440" style="1">ontology or findings,</p>
			<p begin="00:42:04.440" end="00:42:05.360" style="1">constipation,</p>
			<p begin="00:42:05.370" end="00:42:05.910" style="1">anemia,</p>
			<p begin="00:42:05.910" end="00:42:06.460" style="1">weight loss.</p>
			<p begin="00:42:06.460" end="00:42:08.980" style="1">Those things that might suggest a colonic </p>
			<p begin="00:42:08.980" end="00:42:11.920" style="1">malignancy pilots having been </p>
			<p begin="00:42:11.920" end="00:42:14.920" style="1">discovered on a practice ka pik examination or any other kind of </p>
			<p begin="00:42:14.920" end="00:42:15.710" style="1">an examination.</p>
			<p begin="00:42:16.070" end="00:42:18.900" style="1">Any previous history of polyps or cancer of the </p>
			<p begin="00:42:18.900" end="00:42:19.250" style="1">colon.</p>
			<p begin="00:42:19.250" end="00:42:21.750" style="1">Any kind of history like that leads us to do an air contrast </p>
			<p begin="00:42:21.750" end="00:42:22.460" style="1">examination.</p>
			<p begin="00:42:22.760" end="00:42:24.860" style="1">Any family history of polyps or cancer.</p>
			<p begin="00:42:24.860" end="00:42:27.010" style="1">And I&apos;m not even talking about Paula poses of the colon.</p>
			<p begin="00:42:27.010" end="00:42:29.670" style="1">Just a family history of polyps or cancer.</p>
			<p begin="00:42:30.000" end="00:42:32.520" style="1">And then certainly previous colon surgery </p>
			<p begin="00:42:32.800" end="00:42:35.390" style="1">For polyps uh </p>
			<p begin="00:42:35.400" end="00:42:36.120" style="1">cancer.</p>
			<p begin="00:42:36.120" end="00:42:37.980" style="1">We all know about the increased incidents,</p>
			<p begin="00:42:37.980" end="00:42:40.510" style="1">maybe 5% associated </p>
			<p begin="00:42:40.510" end="00:42:43.240" style="1">frequency of synchronous and asynchronous carcinomas of the </p>
			<p begin="00:42:43.240" end="00:42:43.600" style="1">colon.</p>
			<p begin="00:42:43.600" end="00:42:45.260" style="1">So we&apos;re looking for the second lesion,</p>
			<p begin="00:42:45.550" end="00:42:48.440" style="1">the second smaller leading to make sure that the operation </p>
			<p begin="00:42:48.440" end="00:42:50.180" style="1">is complete.</p>
			<p begin="00:42:50.190" end="00:42:52.840" style="1">These are the indications we use them for </p>
			<p begin="00:42:52.990" end="00:42:55.880" style="1">many years patients that you send to us for with pelvic mass.</p>
			<p begin="00:42:56.300" end="00:42:59.260" style="1">Uh Those don&apos;t normally get air contrast in the department unless </p>
			<p begin="00:42:59.260" end="00:43:02.190" style="1">there are other symptoms patients who&apos;ve had radiation </p>
			<p begin="00:43:02.190" end="00:43:05.170" style="1">uh probably having symptoms from radiation practice </p>
			<p begin="00:43:05.450" end="00:43:06.200" style="1">practice.</p>
			<p begin="00:43:06.200" end="00:43:09.120" style="1">Sigmoid itis don&apos;t usually get uh air contrast </p>
			<p begin="00:43:09.120" end="00:43:09.820" style="1">examinations.</p>
			<p begin="00:43:09.820" end="00:43:12.390" style="1">And also if the patient has an unknown </p>
			<p begin="00:43:12.390" end="00:43:15.190" style="1">primary where there is already known malignant disease to </p>
			<p begin="00:43:15.190" end="00:43:17.060" style="1">deliver to the bone to the notes.</p>
			<p begin="00:43:17.400" end="00:43:19.290" style="1">Very common patient in this hospital.</p>
			<p begin="00:43:19.440" end="00:43:21.260" style="1">Those patients don&apos;t get air contrast.</p>
			<p begin="00:43:21.260" end="00:43:23.940" style="1">We feel that we&apos;ll find the tumor if the tumor is the </p>
			<p begin="00:43:23.940" end="00:43:24.610" style="1">unknown primary,</p>
			<p begin="00:43:24.610" end="00:43:26.430" style="1">we&apos;ll find it on a conventional examination.</p>
			<p begin="00:43:27.200" end="00:43:27.730" style="1">Next line,</p>
			<p begin="00:43:29.200" end="00:43:32.120" style="1">here&apos;s an example of a carcinoma of the </p>
			<p begin="00:43:32.120" end="00:43:33.430" style="1">recto sigmoid colon.</p>
			<p begin="00:43:33.430" end="00:43:36.230" style="1">We have a nice feature of it in denting the wall from which it </p>
			<p begin="00:43:36.230" end="00:43:38.440" style="1">arises or pulling in the wall from which it arises.</p>
			<p begin="00:43:38.440" end="00:43:39.370" style="1">A small carcinoma.</p>
			<p begin="00:43:39.370" end="00:43:42.090" style="1">Next line a </p>
			<p begin="00:43:42.090" end="00:43:45.020" style="1">plaque like carcinoma along the posterior wall with the rectum.</p>
			<p begin="00:43:46.900" end="00:43:47.620" style="1">Next line,</p>
			<p begin="00:43:49.800" end="00:43:52.360" style="1">here&apos;s a lobular mass in the ascending colon that </p>
			<p begin="00:43:52.370" end="00:43:53.730" style="1">represented a lie poma.</p>
			<p begin="00:43:54.400" end="00:43:55.120" style="1">Next line,</p>
			<p begin="00:43:56.900" end="00:43:59.310" style="1">here&apos;s a case that was lent to us by dr </p>
			<p begin="00:43:59.320" end="00:44:02.270" style="1">horrible from Hermann Hospital that illustrates </p>
			<p begin="00:44:02.270" end="00:44:02.730" style="1">this.</p>
			<p begin="00:44:03.110" end="00:44:06.010" style="1">This was a barium study done on a patient and the sigmoid </p>
			<p begin="00:44:06.010" end="00:44:08.660" style="1">colon in this region does look abnormal,</p>
			<p begin="00:44:08.660" end="00:44:09.400" style="1">looks very peculiar,</p>
			<p begin="00:44:09.400" end="00:44:10.850" style="1">but it&apos;s a little hard to define.</p>
			<p begin="00:44:11.090" end="00:44:12.810" style="1">There is kind of a scallop defect here,</p>
			<p begin="00:44:12.810" end="00:44:14.570" style="1">but hard to define what&apos;s going on there.</p>
			<p begin="00:44:14.570" end="00:44:15.750" style="1">And appropriately,</p>
			<p begin="00:44:15.760" end="00:44:18.460" style="1">air contrast study was performed the next day or several days </p>
			<p begin="00:44:18.460" end="00:44:18.800" style="1">later.</p>
			<p begin="00:44:19.090" end="00:44:22.030" style="1">Next slide and the question </p>
			<p begin="00:44:22.030" end="00:44:22.790" style="1">is resolved.</p>
			<p begin="00:44:22.790" end="00:44:24.430" style="1">There is a carcinoma of the colon,</p>
			<p begin="00:44:24.430" end="00:44:27.430" style="1">a cecil carcinoma of the colon here and then in addition,</p>
			<p begin="00:44:27.430" end="00:44:29.300" style="1">there is a large sentinel polyps </p>
			<p begin="00:44:31.190" end="00:44:33.720" style="1">in this region that arises from the colon wall </p>
			<p begin="00:44:33.720" end="00:44:35.210" style="1">adjacent to the carcinoma.</p>
			<p begin="00:44:36.490" end="00:44:39.350" style="1">It&apos;s said that as many as 5% we said,</p>
			<p begin="00:44:39.350" end="00:44:42.210" style="1">5% of patients have multiple invasive carcinomas of the </p>
			<p begin="00:44:42.210" end="00:44:42.650" style="1">colon.</p>
			<p begin="00:44:43.290" end="00:44:46.210" style="1">Another 12% of patients who have won carcinoma </p>
			<p begin="00:44:46.210" end="00:44:48.840" style="1">will have associated polyps or carcinomas </p>
			<p begin="00:44:48.840" end="00:44:51.680" style="1">insight to and as maybe as many as 40% of </p>
			<p begin="00:44:51.680" end="00:44:54.430" style="1">patients that have a carcinoma will have at least one other polyps in the </p>
			<p begin="00:44:54.430" end="00:44:57.350" style="1">colon may not always be adjacent to it in some other place </p>
			<p begin="00:44:57.350" end="00:44:57.870" style="1">in the colon.</p>
			<p begin="00:44:57.870" end="00:45:00.420" style="1">So it&apos;s very important to do a complete examination </p>
			<p begin="00:45:00.790" end="00:45:01.800" style="1">prior to surgery.</p>
			<p begin="00:45:01.810" end="00:45:02.410" style="1">Next line.</p>
			<p begin="00:45:04.490" end="00:45:07.440" style="1">Now here makes a point that we&apos;re kind of talking about here </p>
			<p begin="00:45:07.440" end="00:45:10.220" style="1">was a patient that was referred in for this obvious annular </p>
			<p begin="00:45:10.230" end="00:45:12.460" style="1">apple core carcinoma of the sigmoid colon.</p>
			<p begin="00:45:12.470" end="00:45:14.110" style="1">But as we looked around this colon,</p>
			<p begin="00:45:15.990" end="00:45:18.600" style="1">there&apos;s all kinds of filling defects in another carcinoma.</p>
			<p begin="00:45:18.600" end="00:45:21.570" style="1">Up here and here&apos;s a place where colonoscopy will </p>
			<p begin="00:45:21.570" end="00:45:24.280" style="1">be very valuable but wouldn&apos;t be able to get past this </p>
			<p begin="00:45:24.280" end="00:45:25.210" style="1">obstructed area.</p>
			<p begin="00:45:25.220" end="00:45:25.780" style="1">So,</p>
			<p begin="00:45:25.780" end="00:45:26.190" style="1">you know,</p>
			<p begin="00:45:26.200" end="00:45:29.040" style="1">this is an example of where a radiology is important and </p>
			<p begin="00:45:29.040" end="00:45:31.610" style="1">where colonoscopy uh </p>
			<p begin="00:45:32.390" end="00:45:34.830" style="1">can&apos;t be of much use past this area.</p>
			<p begin="00:45:34.830" end="00:45:36.580" style="1">And there are examples to the contrary,</p>
			<p begin="00:45:36.580" end="00:45:36.990" style="1">of course.</p>
			<p begin="00:45:36.990" end="00:45:37.610" style="1">Next slide,</p>
			<p begin="00:45:38.890" end="00:45:41.610" style="1">this same patient also had a third carcinoma </p>
			<p begin="00:45:42.650" end="00:45:43.730" style="1">in the Seattle area,</p>
			<p begin="00:45:43.740" end="00:45:44.420" style="1">descending colon,</p>
			<p begin="00:45:44.420" end="00:45:44.970" style="1">cervical area.</p>
			<p begin="00:45:44.970" end="00:45:47.710" style="1">So this was a patient with three carcinomas and </p>
			<p begin="00:45:47.710" end="00:45:50.180" style="1">multiple other polyps and only one </p>
			<p begin="00:45:50.180" end="00:45:53.090" style="1">identified on an outside study the major </p>
			<p begin="00:45:53.090" end="00:45:54.080" style="1">annular carcinoma.</p>
			<p begin="00:45:54.110" end="00:45:55.420" style="1">Obvious one next line,</p>
			<p begin="00:45:57.890" end="00:46:00.250" style="1">here&apos;s another interesting patient we had not long ago with this </p>
			<p begin="00:46:00.250" end="00:46:03.210" style="1">large villas tumor right here that </p>
			<p begin="00:46:03.210" end="00:46:04.070" style="1">has an obstruction.</p>
			<p begin="00:46:04.280" end="00:46:06.170" style="1">But if we look over here in the ascending colon,</p>
			<p begin="00:46:06.170" end="00:46:07.080" style="1">there&apos;s another lesion.</p>
			<p begin="00:46:07.230" end="00:46:07.790" style="1">Next live,</p>
			<p begin="00:46:09.480" end="00:46:11.380" style="1">here&apos;s a close up of this beautiful villas </p>
			<p begin="00:46:11.380" end="00:46:13.800" style="1">adenocarcinoma of the colon with </p>
			<p begin="00:46:14.180" end="00:46:14.530" style="1">these.</p>
			<p begin="00:46:14.540" end="00:46:17.450" style="1">This is has a network pattern to caused by the very um </p>
			<p begin="00:46:17.450" end="00:46:20.350" style="1">being trapped and interspersed among the </p>
			<p begin="00:46:20.350" end="00:46:23.230" style="1">fronds of the villas tumor and this angular component of the </p>
			<p begin="00:46:23.230" end="00:46:25.040" style="1">tumor indicating it&apos;s malignant nature.</p>
			<p begin="00:46:25.370" end="00:46:28.320" style="1">Next slide and then a close up of this lesion in </p>
			<p begin="00:46:28.320" end="00:46:30.290" style="1">the ascending Siegel region.</p>
			<p begin="00:46:30.780" end="00:46:33.260" style="1">Another example of double primary is not </p>
			<p begin="00:46:33.260" end="00:46:35.070" style="1">uncommon and needs to be examined.</p>
			<p begin="00:46:35.070" end="00:46:36.000" style="1">For next slide </p>
			<p begin="00:46:38.380" end="00:46:40.390" style="1">example of Paula poses of the colon.</p>
			<p begin="00:46:40.390" end="00:46:42.400" style="1">This happened to be a patient with Gardner syndrome.</p>
			<p begin="00:46:42.980" end="00:46:43.600" style="1">Next live </p>
			<p begin="00:46:46.180" end="00:46:47.250" style="1">cone down to you to see them.</p>
			<p begin="00:46:47.250" end="00:46:48.860" style="1">This is kind of the classic examination.</p>
			<p begin="00:46:48.860" end="00:46:51.820" style="1">Everybody knows about air contrast colon examinations for but </p>
			<p begin="00:46:51.820" end="00:46:53.520" style="1">it has obviously many other uses.</p>
			<p begin="00:46:54.080" end="00:46:54.710" style="1">Next line,</p>
			<p begin="00:46:56.080" end="00:46:58.980" style="1">another case of paul opposes the colon with a </p>
			<p begin="00:46:58.980" end="00:47:00.070" style="1">somewhat different appearance,</p>
			<p begin="00:47:00.070" end="00:47:01.430" style="1">more of a carpeting appearance.</p>
			<p begin="00:47:01.590" end="00:47:02.200" style="1">Next lie,</p>
			<p begin="00:47:03.880" end="00:47:05.710" style="1">here&apos;s a gross specimen on that patient.</p>
			<p begin="00:47:06.680" end="00:47:07.430" style="1">Next line,</p>
			<p begin="00:47:07.470" end="00:47:09.110" style="1">the first patient had no malignant tumors.</p>
			<p begin="00:47:09.110" end="00:47:10.000" style="1">This particular patient,</p>
			<p begin="00:47:10.000" end="00:47:12.990" style="1">this last one had three areas of Dominant mass </p>
			<p begin="00:47:12.990" end="00:47:14.860" style="1">or carcinomas in his colon.</p>
			<p begin="00:47:14.860" end="00:47:16.180" style="1">This was one of them in the rectum.</p>
			<p begin="00:47:16.180" end="00:47:17.090" style="1">There were two others.</p>
			<p begin="00:47:18.080" end="00:47:18.590" style="1">Next line.</p>
			<p begin="00:47:20.930" end="00:47:22.530" style="1">I hope this project again.</p>
			<p begin="00:47:22.530" end="00:47:25.350" style="1">I can&apos;t see it from up here but this is an entity seen in Children with </p>
			<p begin="00:47:25.350" end="00:47:28.010" style="1">some frequency called lymphoid hyperplasia.</p>
			<p begin="00:47:28.060" end="00:47:30.720" style="1">It&apos;s common in the terminal ilium and it&apos;s also very common in the </p>
			<p begin="00:47:30.720" end="00:47:31.240" style="1">colon.</p>
			<p begin="00:47:31.490" end="00:47:34.380" style="1">And these little filling defects can look like pops but </p>
			<p begin="00:47:34.380" end="00:47:36.240" style="1">should not be mistaken for polyps.</p>
			<p begin="00:47:36.550" end="00:47:39.350" style="1">These patients are usually asymptomatic and one doesn&apos;t want to </p>
			<p begin="00:47:39.350" end="00:47:42.030" style="1">perform a collecting me on these patients </p>
			<p begin="00:47:42.030" end="00:47:44.100" style="1">for benign lymphoid hyperplasia.</p>
			<p begin="00:47:44.480" end="00:47:47.440" style="1">Next line and here&apos;s </p>
			<p begin="00:47:47.440" end="00:47:50.360" style="1">a most unusual case given to us from texas Children&apos;s hospital </p>
			<p begin="00:47:50.360" end="00:47:53.340" style="1">recently of a long juvenile pilot just showed it </p>
			<p begin="00:47:53.340" end="00:47:56.300" style="1">because of its unusual nature usual appearance.</p>
			<p begin="00:47:57.580" end="00:47:58.210" style="1">Next line </p>
			<p begin="00:48:00.470" end="00:48:03.210" style="1">now we do uh air contrast work </p>
			<p begin="00:48:03.210" end="00:48:04.720" style="1">occasionally for benign disease.</p>
			<p begin="00:48:04.730" end="00:48:07.110" style="1">Uh but not not always.</p>
			<p begin="00:48:07.110" end="00:48:07.770" style="1">Here&apos;s a patient.</p>
			<p begin="00:48:07.770" end="00:48:09.300" style="1">An interesting problem that was resolved.</p>
			<p begin="00:48:09.300" end="00:48:10.020" style="1">Benign diseases.</p>
			<p begin="00:48:10.020" end="00:48:12.940" style="1">Patient had this filling defect in the cycle </p>
			<p begin="00:48:12.950" end="00:48:15.740" style="1">tip on several outside </p>
			<p begin="00:48:15.750" end="00:48:17.120" style="1">uh conventional studies.</p>
			<p begin="00:48:17.120" end="00:48:19.900" style="1">Next slide and with double </p>
			<p begin="00:48:19.900" end="00:48:20.400" style="1">contrast,</p>
			<p begin="00:48:20.400" end="00:48:23.320" style="1">we can see this smooth filling defect and this turned out to </p>
			<p begin="00:48:23.320" end="00:48:26.270" style="1">be an intercepted appendix patient had not </p>
			<p begin="00:48:26.270" end="00:48:27.100" style="1">had his appendix out.</p>
			<p begin="00:48:27.100" end="00:48:29.850" style="1">It&apos;s just that his appendix was intercepted and causing this </p>
			<p begin="00:48:31.550" end="00:48:34.360" style="1">smooth sub mucosal defect in the </p>
			<p begin="00:48:34.370" end="00:48:35.790" style="1">single tip next line.</p>
			<p begin="00:48:37.470" end="00:48:40.460" style="1">And here&apos;s an example of diverticulitis with multiple </p>
			<p begin="00:48:40.460" end="00:48:42.900" style="1">diverticular here and a sigmoid </p>
			<p begin="00:48:43.570" end="00:48:46.240" style="1">vaginal officially diagnosed by double </p>
			<p begin="00:48:46.240" end="00:48:46.990" style="1">contrast,</p>
			<p begin="00:48:47.000" end="00:48:49.320" style="1">this patient had rectal bleeding and was not suspected of having </p>
			<p begin="00:48:49.320" end="00:48:51.710" style="1">diverticulitis and that&apos;s why the patient had an air </p>
			<p begin="00:48:51.710" end="00:48:52.360" style="1">contrast.</p>
			<p begin="00:48:52.370" end="00:48:55.320" style="1">So one can use this technique to diagnose diseases </p>
			<p begin="00:48:55.320" end="00:48:56.220" style="1">such as diverticulitis,</p>
			<p begin="00:48:56.220" end="00:48:58.580" style="1">but this would not normally be an indication </p>
			<p begin="00:48:58.580" end="00:49:01.500" style="1">for uh double contrast work next line </p>
			<p begin="00:49:03.770" end="00:49:05.470" style="1">and inflammatory bowel disease.</p>
			<p begin="00:49:05.470" end="00:49:05.730" style="1">Again,</p>
			<p begin="00:49:05.730" end="00:49:07.810" style="1">we don&apos;t see too much of that at this particular institution,</p>
			<p begin="00:49:07.810" end="00:49:10.520" style="1">but some people have advocated for the more accurate and earlier </p>
			<p begin="00:49:10.520" end="00:49:13.020" style="1">diagnosis of inflammatory policies.</p>
			<p begin="00:49:13.020" end="00:49:14.280" style="1">Here is one such case.</p>
			<p begin="00:49:14.490" end="00:49:17.490" style="1">This is a spot film taken in the distal transverse colon </p>
			<p begin="00:49:17.490" end="00:49:19.900" style="1">and one sees this cobblestone pattern.</p>
			<p begin="00:49:19.900" end="00:49:22.630" style="1">Next slide and in the </p>
			<p begin="00:49:22.640" end="00:49:25.440" style="1">ascending colon there were four areas in this </p>
			<p begin="00:49:25.440" end="00:49:26.160" style="1">patient&apos;s colon.</p>
			<p begin="00:49:26.160" end="00:49:27.440" style="1">You are seeing two of them of this.</p>
			<p begin="00:49:27.440" end="00:49:28.000" style="1">Finally,</p>
			<p begin="00:49:28.000" end="00:49:30.810" style="1">Nigel er cobblestone appearance in this patient with Crohn&apos;s </p>
			<p begin="00:49:30.810" end="00:49:31.200" style="1">disease.</p>
			<p begin="00:49:31.200" end="00:49:31.790" style="1">Of the colon.</p>
			<p begin="00:49:33.170" end="00:49:33.790" style="1">Next line </p>
			<p begin="00:49:35.870" end="00:49:36.580" style="1">finally,</p>
			<p begin="00:49:36.580" end="00:49:39.300" style="1">we&apos;re gonna spend a few moments talking about the post </p>
			<p begin="00:49:39.310" end="00:49:40.280" style="1">operative colon.</p>
			<p begin="00:49:40.280" end="00:49:43.210" style="1">We said that one of the indications was in the postoperative patient to </p>
			<p begin="00:49:43.210" end="00:49:45.390" style="1">find the asynchronous arm attack Cronus </p>
			<p begin="00:49:45.840" end="00:49:48.740" style="1">carcinoma and one can do this in any </p>
			<p begin="00:49:48.740" end="00:49:49.890" style="1">type of post op patient.</p>
			<p begin="00:49:49.900" end="00:49:52.300" style="1">This is a patient that had a primary anastomosis </p>
			<p begin="00:49:53.770" end="00:49:56.750" style="1">and one can visualize the nest emotions very readily with double contrast </p>
			<p begin="00:49:56.750" end="00:49:57.190" style="1">techniques.</p>
			<p begin="00:49:57.190" end="00:49:59.880" style="1">Next live and here is a </p>
			<p begin="00:49:59.880" end="00:50:02.460" style="1">patient who had a right hemi collected me and one can see the </p>
			<p begin="00:50:02.470" end="00:50:05.200" style="1">elio transverse colon anastomosis.</p>
			<p begin="00:50:05.200" end="00:50:07.680" style="1">Not to mention looking at the rest of the colon.</p>
			<p begin="00:50:07.680" end="00:50:10.270" style="1">So we do this in all post op patients where we can </p>
			<p begin="00:50:10.860" end="00:50:13.650" style="1">next line and we&apos;ve </p>
			<p begin="00:50:13.650" end="00:50:16.390" style="1">also been able to evolve a technique here of examining </p>
			<p begin="00:50:16.390" end="00:50:19.170" style="1">colostomy Coghlan&apos;s with air contrast </p>
			<p begin="00:50:19.170" end="00:50:19.690" style="1">techniques.</p>
			<p begin="00:50:19.690" end="00:50:22.510" style="1">We do that by asking the patient to insert a soft </p>
			<p begin="00:50:22.510" end="00:50:24.490" style="1">rubber catheter in through their colostomy.</p>
			<p begin="00:50:24.490" end="00:50:26.440" style="1">Similar to their irrigation practices.</p>
			<p begin="00:50:26.960" end="00:50:29.870" style="1">We tamponade the colostomy stoma with an infant </p>
			<p begin="00:50:29.870" end="00:50:30.650" style="1">feeding nipple.</p>
			<p begin="00:50:30.880" end="00:50:33.840" style="1">And do the conventional examination as I showed you with running the </p>
			<p begin="00:50:33.840" end="00:50:36.080" style="1">barium in part of the way and then introducing air.</p>
			<p begin="00:50:36.460" end="00:50:37.180" style="1">Next slide.</p>
			<p begin="00:50:38.260" end="00:50:41.210" style="1">These are usually these tubes are about 26-30 French and </p>
			<p begin="00:50:41.210" end="00:50:43.570" style="1">they&apos;re about the exact same size as um </p>
			<p begin="00:50:43.960" end="00:50:46.050" style="1">as the colostomy </p>
			<p begin="00:50:46.050" end="00:50:48.980" style="1">irrigating tubing is given to patients in </p>
			<p begin="00:50:48.980" end="00:50:49.660" style="1">this hospital.</p>
			<p begin="00:50:49.670" end="00:50:52.660" style="1">Next line and this is an </p>
			<p begin="00:50:52.660" end="00:50:55.570" style="1">in vitro picture the patient&apos;s introduce this and they always are </p>
			<p begin="00:50:55.570" end="00:50:58.180" style="1">the one to introduce them because they are familiar with the feel of the </p>
			<p begin="00:50:58.560" end="00:51:00.480" style="1">irrigating tube entering their colon,</p>
			<p begin="00:51:00.480" end="00:51:03.470" style="1">introduced this into the descending colon patients holding the </p>
			<p begin="00:51:03.470" end="00:51:06.220" style="1">nipple against the stomach to tamponade the </p>
			<p begin="00:51:06.230" end="00:51:09.180" style="1">stomach to prevent leakage and then the barium and air </p>
			<p begin="00:51:09.180" end="00:51:10.380" style="1">will subsequently be introduced.</p>
			<p begin="00:51:10.380" end="00:51:10.990" style="1">Next slide.</p>
			<p begin="00:51:13.260" end="00:51:15.750" style="1">So this is an upright air </p>
			<p begin="00:51:15.750" end="00:51:17.490" style="1">contrast colostomy enema.</p>
			<p begin="00:51:18.060" end="00:51:21.050" style="1">Next live and </p>
			<p begin="00:51:21.050" end="00:51:21.910" style="1">a cubit is view.</p>
			<p begin="00:51:21.910" end="00:51:24.270" style="1">All the same views are obtained as much as possible.</p>
			<p begin="00:51:25.260" end="00:51:28.220" style="1">Next line an upright spot </p>
			<p begin="00:51:28.220" end="00:51:30.880" style="1">film in the splendid lecture tubes in a little </p>
			<p begin="00:51:30.880" end="00:51:32.780" style="1">farther next line </p>
			<p begin="00:51:34.560" end="00:51:36.530" style="1">and this is the most dramatic case.</p>
			<p begin="00:51:36.530" end="00:51:39.010" style="1">We&apos;ve had to illustrate the value of this technique.</p>
			<p begin="00:51:39.070" end="00:51:40.800" style="1">This was a patient who had a carcinoma,</p>
			<p begin="00:51:40.800" end="00:51:43.630" style="1">the rectum and a colostomy performed about </p>
			<p begin="00:51:43.630" end="00:51:46.380" style="1">four years before and then for the past two years the </p>
			<p begin="00:51:46.380" end="00:51:49.380" style="1">patient had anemia and this patient had four </p>
			<p begin="00:51:49.420" end="00:51:52.210" style="1">uh colon examinations in our department for </p>
			<p begin="00:51:52.210" end="00:51:52.980" style="1">conventional animals.</p>
			<p begin="00:51:52.980" end="00:51:55.780" style="1">I personally did one of them and called it normal.</p>
			<p begin="00:51:56.260" end="00:51:58.990" style="1">Uh in retrospective one looks at the system.</p>
			<p begin="00:51:59.360" end="00:52:01.620" style="1">There does appear to be a vague filling defect,</p>
			<p begin="00:52:01.630" end="00:52:04.250" style="1">but this was a difficult seek them to palpate many times after </p>
			<p begin="00:52:04.250" end="00:52:04.680" style="1">colostomy,</p>
			<p begin="00:52:04.680" end="00:52:07.680" style="1">to seek them will occupy the pelvis and they&apos;re difficult to palpate and put </p>
			<p begin="00:52:07.680" end="00:52:08.770" style="1">pressure on in that region.</p>
			<p begin="00:52:09.350" end="00:52:09.980" style="1">Next line,</p>
			<p begin="00:52:10.850" end="00:52:13.730" style="1">the fifth time we examine this patient with their contrast and found </p>
			<p begin="00:52:13.730" end="00:52:15.970" style="1">this obvious lesion in the second.</p>
			<p begin="00:52:16.750" end="00:52:19.070" style="1">Um This is the </p>
			<p begin="00:52:19.650" end="00:52:20.230" style="1">best case.</p>
			<p begin="00:52:20.230" end="00:52:23.090" style="1">I have to illustrate the value of this technique to this </p>
			<p begin="00:52:23.090" end="00:52:23.480" style="1">point.</p>
			<p begin="00:52:24.050" end="00:52:24.680" style="1">Next slide.</p>
			<p begin="00:52:26.050" end="00:52:28.650" style="1">So in summary double contrast,</p>
			<p begin="00:52:28.660" end="00:52:31.150" style="1">gastrointestinal examinations are simple to </p>
			<p begin="00:52:31.150" end="00:52:31.770" style="1">perform.</p>
			<p begin="00:52:32.550" end="00:52:34.880" style="1">Commercial tools and products are available </p>
			<p begin="00:52:35.350" end="00:52:38.070" style="1">and any department therefore is capable of performing them.</p>
			<p begin="00:52:38.740" end="00:52:41.140" style="1">The esophagus stomach duodenum and colon,</p>
			<p begin="00:52:41.140" end="00:52:44.130" style="1">Both the intact and postoperative colon can be examined with these </p>
			<p begin="00:52:44.130" end="00:52:46.380" style="1">techniques and I hope I&apos;ve tried to </p>
			<p begin="00:52:46.750" end="00:52:49.610" style="1">show you and convince you that these techniques enable </p>
			<p begin="00:52:49.610" end="00:52:52.550" style="1">diagnostic accuracy not possible with conventional barium </p>
			<p begin="00:52:52.550" end="00:52:53.030" style="1">studies.</p>
			<p begin="00:52:53.650" end="00:52:54.610" style="1">I have two more slides.</p>
			<p begin="00:52:54.610" end="00:52:56.610" style="1">I wish there were more clinicians here to see these slides.</p>
			<p begin="00:52:56.610" end="00:52:59.580" style="1">But this is a message from our department at </p>
			<p begin="00:52:59.580" end="00:53:02.350" style="1">least from most of the members of our department to the clinical </p>
			<p begin="00:53:02.350" end="00:53:02.820" style="1">people.</p>
			<p begin="00:53:03.170" end="00:53:03.770" style="1">Next line,</p>
			<p begin="00:53:04.850" end="00:53:07.700" style="1">these are past concepts of radiologists and clinicians have </p>
			<p begin="00:53:07.700" end="00:53:10.530" style="1">had ugly do bizarre things in the </p>
			<p begin="00:53:10.530" end="00:53:10.970" style="1">dark,</p>
			<p begin="00:53:11.650" end="00:53:12.570" style="1">not too bright,</p>
			<p begin="00:53:13.450" end="00:53:15.210" style="1">couldn&apos;t really make it in clinical medicine.</p>
			<p begin="00:53:15.210" end="00:53:16.490" style="1">That&apos;s why they&apos;re in radiology.</p>
			<p begin="00:53:17.020" end="00:53:19.890" style="1">Need a lot of help from clinicians never can make up </p>
			<p begin="00:53:19.890" end="00:53:22.470" style="1">his mind passive and rich.</p>
			<p begin="00:53:22.950" end="00:53:25.770" style="1">Next line these are what present </p>
			<p begin="00:53:25.770" end="00:53:27.190" style="1">concepts and appropriate concept.</p>
			<p begin="00:53:27.190" end="00:53:28.370" style="1">We are all good looking,</p>
			<p begin="00:53:28.750" end="00:53:29.920" style="1">highly intelligent.</p>
			<p begin="00:53:30.290" end="00:53:32.070" style="1">This is the leading medical specialty.</p>
			<p begin="00:53:32.550" end="00:53:34.260" style="1">We are indispensable to clinicians.</p>
			<p begin="00:53:34.650" end="00:53:36.800" style="1">Many of us have never even seen a pair of red goggles,</p>
			<p begin="00:53:36.800" end="00:53:38.950" style="1">let alone warn them were decisive,</p>
			<p begin="00:53:38.950" end="00:53:40.920" style="1">aggressive but we are struggling financially.</p>
			<p begin="00:53:40.930" end="00:53:42.060" style="1">Thank you.</p>
			<p begin="00:53:42.850" end="00:53:43.170" style="1">Yeah.</p>
			<p begin="00:53:44.250" end="00:53:44.590" style="1">Okay.</p>
			<p begin="00:53:47.550" end="00:53:47.870" style="1">Yeah.</p>
		</div>
	</body>
</tt>
