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			<p begin="00:00:00.166" end="00:00:04,999" style="1">Joslin, Best and diabetes.  1963, Length: 00:27:03, Color, Sound.  16 mm to Beta SP </p>
			<p begin="00:00:05.000" end="00:00:20,833" style="1">[...]</p>
			<p begin="00:00:20.833" end="00:00:24,733" style="1">[ Music ]</p>
			<p begin="00:00:24.733" end="00:00:34,333" style="1">[Narrator:] It&apos;s rare indeed that these two world-famous men can be brought together in a film. Dr. Joslin died in 1962 at the age of 93.</p>
			<p begin="00:00:34.333" end="00:00:44,999" style="1">But, fortunately, Dr. Best, who with Dr. Banting discovered insulin, is still with us. When one realizes that there are some 1 and 1/2 million </p>
			<p begin="00:00:45.000" end="00:00:54,200" style="1">diabetics in United States, and another like amount yet undiscovered, or when at any time you or a member of your family can be afflicted with </p>
			<p begin="00:00:54.200" end="00:01:03,700" style="1">this disease, then and then only can one comprehend the full value of the contributions of Dr. Joslin, who devoted a lifetime to perfecting the </p>
			<p begin="00:01:03.700" end="00:01:10,866" style="1">treatment of diabetes, and of Dr. Best the co-discoverer of life-giving insulin.</p>
			<p begin="00:01:10.866" end="00:01:19,699" style="1">[Dr. Root:] Whether you boys know Dr. Best--Dr. Charles Best, who&apos;s coming here today, is the famous doctor who was the co-discoverer </p>
			<p begin="00:01:19.700" end="00:01:30,833" style="1">with Sir Frederick Banting of insulin 40 years ago. He&apos;s coming here to take part and to speak at the Elliott P. Joslin Memorial in Oxford.</p>
			<p begin="00:01:30.833" end="00:01:33,799" style="1">He was a friend of Dr. Joslin&apos;s for many years.</p>
			<p begin="00:01:33.800" end="00:01:37,833" style="1">[Howey:] Dr. Joslin was my doctor. He was great.</p>
			<p begin="00:01:37.833" end="00:01:46,333" style="1">I don&apos;t know? I know he was an old man and yet, somehow, he wasn&apos;t like a lot of other old people.</p>
			<p begin="00:01:46.333" end="00:01:53,633" style="1">[Dr. Root:] Well, he was 93 when he died.[Scott:] Yes, but he was always asking questions </p>
			<p begin="00:01:53.633" end="00:01:59,333" style="1">about our diabetes. Why, he even visited us here at camp just the summer before.</p>
			<p begin="00:01:59.333" end="00:02:01,666" style="1">[ Car horn ]</p>
			<p begin="00:02:01.666" end="00:02:07,066" style="1">[ Music ]</p>
			<p begin="00:02:07.066" end="00:02:18,332" style="1">[Dr. Best:] Dr. Garmin, I know that you and I agree on the tremendous importance of teaching these boys good control of their diabetes.</p>
			<p begin="00:02:18.333" end="00:02:24,466" style="1">As a matter of fact, you should set them a pretty good example; I think. You had diabetes yourself.</p>
			<p begin="00:02:24.466" end="00:02:31,499" style="1">[Dr. Garmin] Well, there are three things Dr. Best. First, the very close care that my mother gave me when I was a child.</p>
			<p begin="00:02:31.500" end="00:02:39,866" style="1">And second, the almost imperceptible transfer of responsibility during my adolescence.</p>
			<p begin="00:02:39.866" end="00:02:47,966" style="1">And finally, the factor common at all times was the close association and friendship with my physician.</p>
			<p begin="00:02:47.966" end="00:02:53,866" style="1">[Dr. Root:] Dr. Best, I would like to have you meet one of Dr. Joslin&apos;s former patients; Scott Currier.</p>
			<p begin="00:02:53.866" end="00:02:57,232" style="1">[Dr. Best:] Scott. How did you happen to come to this camp?</p>
			<p begin="00:02:57.233" end="00:03:04,599" style="1">[Scott:] Dr. White. She&apos;s at the clinic too.She suggested it to my folks. Dr. Joslin always </p>
			<p begin="00:03:04.600" end="00:03:09,000" style="1">used to tell me how important it was to take care of my own diabetes.</p>
			<p begin="00:03:09.000" end="00:03:16,733" style="1">[Howey:] He told everyone that. That&apos;s one reason he started the camp: to teach diabetics how to take care of themselves.</p>
			<p begin="00:03:16.733" end="00:03:23,999" style="1">[Dr. Joslin:] We have had a wonderful group of patients. To all of those who had lived longer with </p>
			<p begin="00:03:24.000" end="00:03:34,466" style="1">their diabetes and they were expected to live if they didn&apos;t have it, Ms. Amelia Peabody made a life expectancy medal.</p>
			<p begin="00:03:34.466" end="00:03:49,899" style="1">This was given and now we even took two or three thousand patients. And they have cherished it because it showed how faithfully they had lived.</p>
			<p begin="00:03:49.900" end="00:04:04,000" style="1">But so many of them obtained it that later we had another medal for patients. And this was given to those who after 25 years of the disease; </p>
			<p begin="00:04:04.000" end="00:04:16,233" style="1">had perfect blood vessels, perfect eyesight, and perfect kidneys, and were generally sound in health.</p>
			<p begin="00:04:16.233" end="00:04:33,499" style="1">Of these, we have had now some 98 patients. Not one who has obtained this medal of perfection, ever was able to obtain it unless he </p>
			<p begin="00:04:33.500" end="00:04:41,100" style="1">had followed treatment meticulously just as [inaudible] and Alan prescribed.</p>
			<p begin="00:04:41.100" end="00:04:45,866" style="1">[Dr. Best:] Scott, what do you mean when you say take care of yourself?</p>
			<p begin="00:04:45.866" end="00:04:51,099" style="1">[Howey:] Well, I think I can show you better. Come on over to the clinic, we&apos;ll show you.</p>
			<p begin="00:04:51.100" end="00:05:00,033" style="1">Hey, tell Stevie to come here a minute. Steve is the youngest boy in camp who takes his own insulin injection, Dr. Best.</p>
			<p begin="00:05:00.033" end="00:05:03,799" style="1">He&apos;s only seven and already he&apos;s learned to take care of himself this way.</p>
			<p begin="00:05:03.800" end="00:05:07,600" style="1">[Camp staffer:] Okay, boys.[Steve:] What you want? I got to take my shot!</p>
			<p begin="00:05:07.600" end="00:05:31,366" style="1">[Howey:] Hey, Steve, how about giving Dr. Best a performance?</p>
			<p begin="00:05:31.366" end="00:05:36,999" style="1">[Steve:] Well, that&apos;s that. Me and Art have to go and eat.</p>
			<p begin="00:05:37.000" end="00:05:46,666" style="1">[Howey:] He&apos;s a cute kid but, boy, he can be a pill. Now we&apos;ll never hear the end of it: &quot;I shot myself for Dr. Best.&quot;</p>
			<p begin="00:05:46.666" end="00:05:52,199" style="1">[Scott:] Years ago when doctors didn&apos;t know what they know now, the kids just didn&apos;t get very tall.</p>
			<p begin="00:05:52.200" end="00:05:56,200" style="1">[Howey:] Sure, I know that. They used to call them diabetic dwarfs.</p>
			<p begin="00:05:56.200" end="00:06:04,600" style="1">[Scott:] It was because they didn&apos;t get enough protein in their diet. Now we know we must take care of our height, our weight, as well as our diet.</p>
			<p begin="00:06:04.600" end="00:06:10,666" style="1">[Dr. Best:] You mean that you weigh and measure your food and know how to prepare it?</p>
			<p begin="00:06:10.666" end="00:06:19,299" style="1">[Scott:] Here, let me show you in the diet kitchen. I have a diet of so much fat, protein, and carbohydrate and I use one of these scales</p>
			<p begin="00:06:19.300" end="00:06:25,533" style="1">to measure it.  I check myself about once a week now but I&apos;ve been doing it for so long,</p>
			<p begin="00:06:25.533" end="00:06:31,399" style="1">I think my estimates are perfectly all right; at least the doctor and the dietitian think so.</p>
			<p begin="00:06:31.400" end="00:06:40,700" style="1">[Dr. Best:] Do you find, Scott, that it takes a lot of time to weigh your food and take your insulin shots? Do you find it hard to do?</p>
			<p begin="00:06:40.700" end="00:06:47,400" style="1">[Scott:] Well, at first it was sort of a hard thing and then I became used to it. And now it&apos;s nothing at all.</p>
			<p begin="00:06:47.400" end="00:06:51,000" style="1">[Howey:] It&apos;s really not even as hard as seventh-grade math.</p>
			<p begin="00:06:51.000" end="00:07:00,300" style="1">[Scott:] Hi, Betty. I was just showing Dr. Best how we weigh and measure our food; the kind of thing that Dr. Joslin used to teach us.</p>
			<p begin="00:07:00.300" end="00:07:06,100" style="1">[Betty:] He was always interested in the children knowing how to do these things. Howey, where&apos;s Beetle.</p>
			<p begin="00:07:06.100" end="00:07:10,400" style="1">[Howey:] I think he&apos;s down by the lake.[Betty:] Well, when you see him, would you give </p>
			<p begin="00:07:10.400" end="00:07:16,133" style="1">this to him? [Howey:] Wow! Sure! This is for Beetle Daws. </p>
			<p begin="00:07:16.133" end="00:07:21,899" style="1">He&apos;s bugs about bugs.[Scott:] You know, the camp is for fun too.</p>
			<p begin="00:07:21.900" end="00:07:27,300" style="1">We do everything they do at any camp. You don&apos;t have to feel you&apos;re sitting on a bench if you&apos;re diabetic.</p>
			<p begin="00:07:27.300" end="00:08:11,133" style="1">[ Music and clapping ]</p>
			<p begin="00:08:11.133" end="00:08:17,399" style="1">[Dr. Best:] You know boys with all this activity around the camp, makes me think of another one of Dr. Joslin&apos;s great interests. </p>
			<p begin="00:08:17.400" end="00:08:23,100" style="1">He was always trying to find out the influence of exercise on diabetes.</p>
			<p begin="00:08:23.100" end="00:08:30,733" style="1">[Dr. Joslin:] Now, [inaudible] found this. And this puzzled him and embarrassed him.</p>
			<p begin="00:08:30.733" end="00:08:42,999" style="1">He found that the patients to whom he gave a diet--the same diet that he had in the hospital--and sent them home, that they did better when they </p>
			<p begin="00:08:43.000" end="00:08:53,533" style="1">were away from him at home on their farms than when he had them in a hospital. And it finally dawned upon him</p>
			<p begin="00:08:53.533" end="00:09:00,499" style="1">that exercise was the reason for it.[Dr. Best:] Thank you, Scott. </p>
			<p begin="00:09:00.500" end="00:09:06,200" style="1">Thank you, too, for acting as the host at the camp for us today.</p>
			<p begin="00:09:06.200" end="00:09:15,100" style="1">[Howey:] There&apos;s a girls&apos; camp, the Clara Barton camp, that has a program just like ours. Boy, won&apos;t they flip when they find out that you&apos;ve been here and not there.</p>
			<p begin="00:09:15.100" end="00:09:22,266" style="1">[Dr. Best:] Well, as matter of fact, I&apos;m going over to the Clara Barton camp tomorrow after the dedication.</p>
			<p begin="00:09:22.266" end="00:09:28,199" style="1">Are you boys going to be at the dedication?[Scott:] You bet! I wouldn&apos;t miss that for anything. [Howey:] Me too.</p>
			<p begin="00:09:28.200" end="00:09:38,000" style="1">[ Music ]</p>
			<p begin="00:09:38.000" end="00:09:46,300" style="1">[Dr. Root:] We are meant today to celebrate the 250th anniversary of the founding of Oxford, Massachusetts.</p>
			<p begin="00:09:46.300" end="00:09:54,566" style="1">In this city were born two persons who achieved distinction by their service to humanity.</p>
			<p begin="00:09:54.566" end="00:10:05,999" style="1">Clara Barton. Born in Oxford in 1821. She brought about the formation of the United States branch of the International Red Cross.</p>
			<p begin="00:10:06.000" end="00:10:16,266" style="1">Dr. Elliott P. Joslin, born here in 1869, became a professor of medicine, a distinguished physician and known the world over for his teachings </p>
			<p begin="00:10:16.266" end="00:10:21,666" style="1">in diabetes. But my real privilege today is the introduction of Dr. Charles H. Best.</p>
			<p begin="00:10:21.666" end="00:10:29,866" style="1">[Dr. Best:] Thank you Dr. Root. I enjoyed every time I ever met Dr. Elliott P. Joslin.</p>
			<p begin="00:10:29.866" end="00:10:35,699" style="1">And I&apos;m delighted to have this opportunity to pay a tribute to his memory.</p>
			<p begin="00:10:35.700" end="00:11:05,000" style="1">[ Music ]</p>
			<p begin="00:11:05.000" end="00:11:13,066" style="1">[Susie:] Dr. Best, many of us knew Dr. Joslin rather well too. And your speech at Oxford really meant a lot to us. Some of the things you said </p>
			<p begin="00:11:13.066" end="00:11:18,032" style="1">were just the way we felt about him. [Dr. Best:] Thank you, Susie. Dr. Joslin knew </p>
			<p begin="00:11:18.033" end="00:11:24,066" style="1">how to say things wonderfully well.I&apos;ve enjoyed having the tour of the Clara Barton </p>
			<p begin="00:11:24.066" end="00:11:29,732" style="1">camp with you three girls. And I&apos;m amazed at how many things you&apos;ve learned to do well.</p>
			<p begin="00:11:29.733" end="00:11:36,933" style="1">[Cathy:] We&apos;ve been wondering just what did happen to the children in the days before insulin? What was it like?</p>
			<p begin="00:11:36.933" end="00:11:45,966" style="1">[Dr. Best:] Well, Cathy, there were thousands of years after diabetes was discovered when there wasn&apos;t much you could do for children.</p>
			<p begin="00:11:45.966" end="00:11:55,232" style="1">You fed them as little as possible and they lived for a time.  Then in 1921 and 22, when we had insulin, </p>
			<p begin="00:11:55.233" end="00:11:59,866" style="1">the first children did very well. But we didn&apos;t have much insulin.</p>
			<p begin="00:11:59.866" end="00:12:09,999" style="1">And with one or two of the children, we ran out of insulin and we lost a little girl. One little girl and one boy.</p>
			<p begin="00:12:10.000" end="00:12:14,133" style="1">[Susie:] You know, Dr. Best, that Dr. Joslin took care of my mother?</p>
			<p begin="00:12:14.133" end="00:12:17,333" style="1">[Dr. Best:] Yeah.[Susie:] In fact he warned her that I had a good </p>
			<p begin="00:12:17.333" end="00:12:23,899" style="1">chance of becoming a diabetic.[Dr. Best:] Yes, we know Susie that diabetes does run in families</p>
			<p begin="00:12:23.900" end="00:12:32,333" style="1">and it&apos;s passed down from the mother or the father to some of the children.  Linda, someone told me that you&apos;ve been in the </p>
			<p begin="00:12:32.333" end="00:12:36,366" style="1">camp here for seven summers. You&apos;d come for seven summers.</p>
			<p begin="00:12:36.366" end="00:12:39,299" style="1">[Linda:] Yes, I&apos;ve been coming to Clara Barton for seven summers now.</p>
			<p begin="00:12:39.300" end="00:12:44,066" style="1">[Dr. Best:] And what are your parents think about your coming?  Do you think that they&apos;re very pleased?</p>
			<p begin="00:12:44.066" end="00:12:48,066" style="1">Have you learned something that gives them satisfaction?</p>
			<p begin="00:12:48.066" end="00:12:50,499" style="1">[Linda:] Yes. They&apos;re pleased that I&apos;ve come to camp.</p>
			<p begin="00:12:50.500" end="00:12:57,666" style="1">Because by coming to camp, I&apos;ve learned to take care of myself by adjusting my diet and my insulin. Taking the right amount of exercise so I </p>
			<p begin="00:12:57.666" end="00:13:00,832" style="1">can control my diabetes by myself.[Dr. Best:] Yeah.</p>
			<p begin="00:13:00.833" end="00:13:04,799" style="1">[Linda:] Which puts them at ease. Because when I go away from home, they won&apos;t have to worry about me.</p>
			<p begin="00:13:04.800" end="00:13:09,800" style="1">[Dr. Best:] Well, I think you&apos;re right, Linda. This is a wonderful camp.</p>
			<p begin="00:13:09.800" end="00:13:19,966" style="1">I&apos;ve been to a lot of other camps. And after thinking about them, I feel that they do a great deal not only for the children but for the parents.</p>
			<p begin="00:13:19.966" end="00:13:30,632" style="1">Well, girls, Dr. Joslin was very much interested in these diabetic camps too. He used to talk about them when I saw him in Boston.</p>
			<p begin="00:13:30.633" end="00:13:37,899" style="1">And I remember he mentioned them when came to Toronto to see the opening of our research institute.</p>
			<p begin="00:13:37.900" end="00:13:48,066" style="1">Dr. Joslin was interested in investigation, you know, research.  And he was interested in the camps.  And he told us at that time</p>
			<p begin="00:13:48.066" end="00:13:55,832" style="1">that he hoped someday he&apos;d have a wonderful clinic where he could do all or many things that he had in his mind to do for diabetics.</p>
			<p begin="00:13:55.833" end="00:14:03,499" style="1">Well, as you know, that clinic really has come into being and I hope to go there again tomorrow.</p>
			<p begin="00:14:03.500" end="00:14:18,733" style="1">[Dr. Joslin:] To predict the future diabetic: we hope to erect in Boston a hospital teaching clinic in which ambulatory diabetics can return at much </p>
			<p begin="00:14:18.733" end="00:14:35,233" style="1">less than regular hospital costs--fully a third less--receive instruction, encouragement, and such development of character that life and health </p>
			<p begin="00:14:35.233" end="00:14:43,433" style="1">hither to unrecorded for diabetics will be obtained.</p>
			<p begin="00:14:43.433" end="00:14:57,599" style="1">[ Music ]</p>
			<p begin="00:14:57.600" end="00:15:07,900" style="1">[Dr. Best:] It&apos;s nearly 10 years ago now since Dr. Joslin came to Toronto to take part in the opening of the institute which they named after me. </p>
			<p begin="00:15:07.900" end="00:15:14,666" style="1">Two years later, the cornerstone of this Joslin clinic was laid.</p>
			<p begin="00:15:14.666" end="00:15:23,332" style="1">and here we are now in the completed clinic which Dr. Joslin had so much desired.</p>
			<p begin="00:15:23.333" end="00:15:34,966" style="1">[Dr. Root:] Yes, Dr. Best. This clinic has fulfilled not only the ideals which he expressed there in founding your institute, but also the hopes which </p>
			<p begin="00:15:34.966" end="00:15:39,299" style="1">you know he had as long ago as 1922 when you first came to Boston.</p>
			<p begin="00:15:39.300" end="00:15:50,566" style="1">And here are the opportunities for training patients an adequate and proper diet is more important today in the treatment of diabetes than </p>
			<p begin="00:15:50.566" end="00:16:01,032" style="1">ever before. And here we emphasize the doctors teaching patients how to measure and evaluate food.</p>
			<p begin="00:16:01.033" end="00:16:12,399" style="1">When a child develops diabetes, it helps tremendously if the child and her mother can together in the same room be treated and the </p>
			<p begin="00:16:12.400" end="00:16:23,833" style="1">mother learn firsthand the best methods for the care of that child. Perhaps the most important single thing for a diabetic patient to learn is how to </p>
			<p begin="00:16:23.833" end="00:16:31,499" style="1">test the urine for sugar and when to do it.  One important aspect of our program is the</p>
			<p begin="00:16:31.500" end="00:16:42,700" style="1">doctors&apos; teaching of patients. Mrs. Cohan. You have known the teaching and training in diabetes over many years which Dr. Joslin inculcated.</p>
			<p begin="00:16:42.700" end="00:16:49,333" style="1">May I ask you how you feel about it?[Mrs. Cohan:] When I first came here 25 years </p>
			<p begin="00:16:49.333" end="00:16:59,799" style="1">ago with my daughter, who was then a child diabetic and myself; I was worried, alarmed, tortured how I was going to care for both herself </p>
			<p begin="00:16:59.800" end="00:17:07,733" style="1">and myself. After being a week at the clinic in the teaching unit, I learned how to take care of us.</p>
			<p begin="00:17:07.733" end="00:17:19,433" style="1">I learned all about diet and food, exercise, the care of the infant to such a great degree that I was completely in confidence. I had the absolute </p>
			<p begin="00:17:19.433" end="00:17:23,433" style="1">confidence that I can go home and take care of all my problems.</p>
			<p begin="00:17:23.433" end="00:17:29,833" style="1">My fears were gone, and I felt that I could do all that was necessary for the best for both of us.</p>
			<p begin="00:17:29.833" end="00:17:35,399" style="1">[Woman speaker 1:] Can you have diabetes without having any apparent symptoms?</p>
			<p begin="00:17:35.400" end="00:17:43,600" style="1">[Dr. Krall:] Why, yes, of course. Very early in diabetes sometimes there are no symptoms and you have to find elevated blood sugars or urine </p>
			<p begin="00:17:43.600" end="00:17:46,833" style="1">sugars.[Male speaker 1:] Is necessary to keep insulin in </p>
			<p begin="00:17:46.833" end="00:17:49,699" style="1">the refrigerator?[Dr. Krall:] The insulin you are storing should be </p>
			<p begin="00:17:49.700" end="00:17:53,566" style="1">kept in the refrigerator. But the insulin that you&apos;re using can be kept at room temperature.</p>
			<p begin="00:17:53.566" end="00:18:01,532" style="1">[Woman speaker 2:] If one member of the family has diabetes, should the other members of the same family be checked?</p>
			<p begin="00:18:01.533" end="00:18:09,299" style="1">[Dr. Krall:] Why, certainly. Diabetes has hereditary tendencies and other members of family should be checked particularly those who </p>
			<p begin="00:18:09.300" end="00:18:13,566" style="1">are overweight; if any.[Male speaker 2:] These pills sound exciting. </p>
			<p begin="00:18:13.566" end="00:18:18,032" style="1">Can all diabetics use these pills?[Dr. Krall:] No, I&apos;m afraid not. While many of the </p>
			<p begin="00:18:18.033" end="00:18:26,133" style="1">diabetics who are milder get by with pills perfectly well, most diabetics and certainly more severe ones still require insulin.</p>
			<p begin="00:18:26.133" end="00:18:35,333" style="1">[Dr. Best:] We all agree that one of the most important things in looking after diabetics is to teach them. I know that this has done </p>
			<p begin="00:18:35.333" end="00:18:41,633" style="1">extremely well in the clinic here.  I&apos;ve seen Dr. Joslin, Hugh Howard and many others</p>
			<p begin="00:18:41.633" end="00:18:52,333" style="1">giving a great deal of their time to patient education. Dr. Root, I know that Dr. Joslin has been interested for many, many years in training </p>
			<p begin="00:18:52.333" end="00:18:58,199" style="1">physicians in the various aspects of diabetes.And that they&apos;ve come to him from all over the world.</p>
			<p begin="00:18:58.200" end="00:19:02,733" style="1">[Dr. Root:] Yes.  And today we have a group of doctors from many countries</p>
			<p begin="00:19:02.733" end="00:19:08,933" style="1">in various types of training. In fact, they have a number of questions to ask you, Dr. Best.</p>
			<p begin="00:19:08.933" end="00:19:17,133" style="1">[Doctor 1:] I&apos;ve always wondered, Dr. Best, how you happen to find insulin and many other researchers have failed?</p>
			<p begin="00:19:17.133" end="00:19:28,233" style="1">[Dr. Best:] I suppose there&apos;s an element of good fortune and all successful research. We had several assets really.</p>
			<p begin="00:19:28.233" end="00:19:34,166" style="1">We had good surgery. Fred Banting was an excellent surgeon.</p>
			<p begin="00:19:34.166" end="00:19:45,832" style="1">And then we had the micro methods for doing blood sugar which all our predecessors had lacked. And then we had youth.</p>
			<p begin="00:19:45.833" end="00:19:49,266" style="1">We weren&apos;t too much concerned about what happened before we started.</p>
			<p begin="00:19:49.266" end="00:19:56,232" style="1">[Doctor 2:] Dr. Best, you have a long-range picture of the diabetes mellitus problem. Could you tell us what advances you hope will be made </p>
			<p begin="00:19:56.233" end="00:20:01,766" style="1">for the diabetic patient in the next 10 years?[Dr. Best:] Well, of course, no one can be </p>
			<p begin="00:20:01.766" end="00:20:13,432" style="1">completely certain about any research problem--about the solution of any research problem until it&apos;s actually accomplish. But I think the indications </p>
			<p begin="00:20:13.433" end="00:20:19,433" style="1">are that we will have synthetic insulin.It won&apos;t be any different perhaps in potency than </p>
			<p begin="00:20:19.433" end="00:20:26,399" style="1">the natural insulin. But we&apos;re going to need some day more insulin than you can make from natural sources.</p>
			<p begin="00:20:26.400" end="00:20:35,566" style="1">[Doctor 3] I think we all like to be interested, Dr. Best, to know how you went about getting the first insulin and also getting enough of it?</p>
			<p begin="00:20:35.566" end="00:20:44,332" style="1">[Dr. Best:] Well, our first insulin was made from dog pancreas. It was very good material, but of course you can&apos;t collect a lot of pancreas from </p>
			<p begin="00:20:44.333" end="00:20:50,466" style="1">dogs.  Then we went to beef pancreas. And this proved to be an excellent source. </p>
			<p begin="00:20:50.466" end="00:20:56,599" style="1">We had to change the technique of extraction a bit, use different strengths of alcohol and acid,</p>
			<p begin="00:20:56.600" end="00:21:01,966" style="1">and so on. But the main problem at that time was to get into large-scale production.</p>
			<p begin="00:21:01.966" end="00:21:11,466" style="1">We did some of the preliminary work in the University of Toronto, but we were fortunate to have the cooperation of one of the great family </p>
			<p begin="00:21:11.466" end="00:21:21,366" style="1">companies in the United States the Eli Lily company. And their engineers were expert in doing the sort of thing that needed to be done.</p>
			<p begin="00:21:21.366" end="00:21:31,732" style="1">I remember that I went there nine times in the first year to try to tell them what I knew. And they taught us a very great deal.</p>
			<p begin="00:21:31.733" end="00:21:42,633" style="1">And I think the insulin committee of the University of Toronto was very happy that we selected the Eli Lily company to work with us for the first </p>
			<p begin="00:21:42.633" end="00:21:49,533" style="1">preliminary difficult year in the large-scale production of insulin.</p>
			<p begin="00:21:49.533" end="00:22:02,233" style="1">[Doctor 4:] Dr. Best, in your travel around the world, do you find the society of free people developing programs in the field of diabetes?</p>
			<p begin="00:22:02.233" end="00:22:12,033" style="1">[Dr. Best:] Well, Dr. Joslin and I had the honor of being the first honorary presidents of the International Diabetes Federation. </p>
			<p begin="00:22:12.033" end="00:22:18,899" style="1">And over the years, I&apos;ve been in a great many countries where societies devoted to the interest of diabetics have been formed.</p>
			<p begin="00:22:18.900" end="00:22:27,533" style="1">In some countries, these societies are doing a wonderful work. And in others, of course, it&apos;s slow.</p>
			<p begin="00:22:27.533" end="00:22:39,833" style="1">But the idea of the International Diabetes Federation is to use the knowledge gained in the more active countries and to apply this in the </p>
			<p begin="00:22:39.833" end="00:22:50,133" style="1">effort to help those countries which are not so fortunate. Dr. Lozano, you&apos;re finishing your two years here in the clinic and you&apos;re going back to </p>
			<p begin="00:22:50.133" end="00:22:54,466" style="1">Mexico. Do you feel that you will be able to apply a lot of </p>
			<p begin="00:22:54.466" end="00:22:57,732" style="1">the new information which you gained while you were here?</p>
			<p begin="00:22:57.733" end="00:23:08,199" style="1">[Dr. Lozano:] Yes, I do. I will work in the Hospital of Nutrition Disease where, like many other places in Mexico, we have a high standard of medicine.</p>
			<p begin="00:23:08.200" end="00:23:19,233" style="1">Of course, there are areas in Latin America as in other parts of the world where getting enough food for the children is a special problem.</p>
			<p begin="00:23:19.233" end="00:23:25,066" style="1">[Dr. Root:] And finally, now, his best hope: his deepest hope:</p>
			<p begin="00:23:25.066" end="00:23:36,832" style="1">a new laboratory for research. One of Dr. Joslin&apos;s most absorbing interest in the last 20 years has been the study and prevention </p>
			<p begin="00:23:36.833" end="00:23:40,533" style="1">of blood vessel disease. Dr. Reese, you are conducting research in this field.</p>
			<p begin="00:23:40.533" end="00:23:45,433" style="1">Tell us about it.[Dr. Reese:] Our research has been directed at </p>
			<p begin="00:23:45.433" end="00:23:55,066" style="1">the relationship between the control of diabetes and the progression of small blood vessel disease. </p>
			<p begin="00:23:55.066" end="00:24:00,499" style="1">Studies today clearly indicate that good control retards the progression of small blood vessel disease in diabetes.</p>
			<p begin="00:24:00.500" end="00:24:10,933" style="1">Another aspect of our research focuses upon the blood vessels of children who have a high index or chance of developing diabetes.  </p>
			<p begin="00:24:10.933" end="00:24:19,133" style="1">With this camera, we can pick up abnormalities a blood vessel before there&apos;s any evidence of diabetes by the usual clinical criteria.</p>
			<p begin="00:24:19.133" end="00:24:33,266" style="1">[Dr. Best:] I suppose, Dr. Root, that this clinic has a very special meaning for you personally. You are Dr. Joslin&apos;s first associate, </p>
			<p begin="00:24:33.266" end="00:24:37,832" style="1">and I believe that you gave the first dose of insulin that was administered in New England.</p>
			<p begin="00:24:37.833" end="00:24:43,766" style="1">[Dr. Root:] Yes, Charlie. But let me say this...eEven before the discovery of insulin, </p>
			<p begin="00:24:43.766" end="00:24:52,132" style="1">Dr. Joslin had demonstrated that devotion to the care of the patient. That keen interest in learning and in teaching.</p>
			<p begin="00:24:52.133" end="00:25:05,666" style="1">When we learned that you and Dr. Banting had each given yourselves a dose of insulin, although neither of you had diabetes</p>
			<p begin="00:25:05.666" end="00:25:10,032" style="1">[Dr. Best:] Right.[Dr. Root:] I should not have been so terrified as I </p>
			<p begin="00:25:10.033" end="00:25:21,333" style="1">was on that day on August 7, 1922 when there stood before me this frail nurse. The diabetes which had reduced her weight from 135 pounds </p>
			<p begin="00:25:21.333" end="00:25:24,433" style="1">to 65 pounds. How much insulin should I give her?</p>
			<p begin="00:25:24.433" end="00:25:27,799" style="1">[Dr. Best:] How much did you actually give her?[Dr. Root:] I have to admit, Charlie, I gave her one unit and my heart beat.</p>
			<p begin="00:25:27.800" end="00:25:33,200" style="1">[Dr. Best:] Yeah.</p>
			<p begin="00:25:33.200" end="00:25:39,533" style="1">[Dr. Root:] And there, there she is. The nurse who learned to give insulin.</p>
			<p begin="00:25:39.533" end="00:25:42,633" style="1">She was then the lovely Ms. Peterson. And now Mrs. Simons.</p>
			<p begin="00:25:42.633" end="00:25:47,333" style="1">Mrs. Simons, what do you remember of that period in 1922?</p>
			<p begin="00:25:47.333" end="00:25:55,899" style="1">[Mrs. Simons:] I remember particularly the children because they started to grow and thrive and live happily.</p>
			<p begin="00:25:55.900" end="00:26:07,233" style="1">[Dr. Root:] And in those next months, she was the nurse first instructed to teach the administration of insulin among the nurses</p>
			<p begin="00:26:07.233" end="00:26:10,299" style="1">[Dr. Best:] Yes.[Dr. Root:] of the Deacons Hospital.</p>
			<p begin="00:26:10.300" end="00:26:19,066" style="1">[Dr. Best:] Dr. Elliott Proctor Joslin was one of the greatest men whom I&apos;ve ever known. I heard his name when I was seven years old.</p>
			<p begin="00:26:19.066" end="00:26:30,332" style="1">I met him in Toronto in 1922 and I was in very close touch with him throughout the rest of his life. I&apos;m sure that I speak for everyone who&apos;s </p>
			<p begin="00:26:30.333" end="00:26:34,799" style="1">taken a part in making this record. We all feel highly honored.</p>
			<p begin="00:26:34.800" end="00:26:45,633" style="1">[Narrator:] And so, since 1922, with the discovery of insulin by doctors Banting and Best and the leadership of Dr. Elliott P Joslin </p>
			<p begin="00:26:45.633" end="00:26:56,733" style="1">in development of a program of patient care, there has evolved a new life; a normal life for millions of diabetics and their families. </p>
			<p begin="00:26:56.733" end="00:27:03,799" style="1">[ All singing ]</p>
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