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			<p begin="00:00:00.000" end="00:00:08,633" style="1">Now in 1928 there occurred in Great Britain,</p>
			<p begin="00:00:08.633" end="00:00:16,499" style="1">a discovery which was terribly upsetting to all of us, and especially to Dr. Avery.</p>
			<p begin="00:00:16.500" end="00:00:31,333" style="1">Namely, an officer of the British Ministry of Health, Fred Griffith,</p>
			<p begin="00:00:31.333" end="00:00:34,699" style="1">demonstrated to his satisfaction,</p>
			<p begin="00:00:34.700" end="00:00:38,766" style="1">very, very crude experiments in mice.</p>
			<p begin="00:00:38.766" end="00:00:42,166" style="1">That those pneumococcus types, </p>
			<p begin="00:00:42.166" end="00:00:45,932" style="1">that all of us were so convinced were so stable,</p>
			<p begin="00:00:45.933" end="00:00:55,399" style="1">were, in reality, could be changed from one to the other in the bodies of mice. </p>
			<p begin="00:00:55.400" end="00:00:58,466" style="1">These experiments were extremely complicated;</p>
			<p begin="00:00:58.466" end="00:01:03,199" style="1">technically, they were not very convincing,</p>
			<p begin="00:01:03.200" end="00:01:10,566" style="1">except that Fred Griffith was a person of such technical mastery</p>
			<p begin="00:01:10.566" end="00:01:13,532" style="1">that one had to take notice of it.</p>
			<p begin="00:01:13.533" end="00:01:22,866" style="1">Well, we took notice of it.  We had countless discussions in the laboratory about the possibility</p>
			<p begin="00:01:22.866" end="00:01:28,932" style="1">that specific pneumococcus types could change one into the other.</p>
			<p begin="00:01:28.933" end="00:01:31,766" style="1">But Dr. Avery could not accept it.</p>
			<p begin="00:01:31.766" end="00:01:40,166" style="1">It went too much against all that he had taught for ten or 15 years,</p>
			<p begin="00:01:40.166" end="00:01:44,266" style="1">and too much against the achievements of his laboratory.</p>
			<p begin="00:01:44.266" end="00:01:50,766" style="1">So that, we did not repeat the experiments of Fred Griffith,</p>
			<p begin="00:01:50.766" end="00:01:53,532" style="1">even though we were fully aware of them.</p>
			<p begin="00:01:53.533" end="00:02:02,233" style="1">[Avery] left for his summer vacation in 1929,</p>
			<p begin="00:02:02.233" end="00:02:06,766" style="1">going to Deer Isle in Maine, where he went every summer,</p>
			<p begin="00:02:06.766" end="00:02:11,399" style="1">and I stayed in the laboratory as I did in those days,</p>
			<p begin="00:02:11.400" end="00:02:17,500" style="1">and if I mention myself, it is not for my participation in the problem,</p>
			<p begin="00:02:17.500" end="00:02:21,666" style="1">it is that I was witness of the experiments</p>
			<p begin="00:02:21.666" end="00:02:28,866" style="1">and participated a bit in the experiments that confirmed Griffith&apos;s studies,</p>
			<p begin="00:02:28.866" end="00:02:33,199" style="1">here, on the 6th floor of the hospital.</p>
			<p begin="00:02:33.200" end="00:02:38,500" style="1">I shared the laboratory with a Canadian.</p>
			<p begin="00:02:38.500" end="00:02:48,433" style="1">A Canadian physician who took care of patients suffering from lobar pneumonia, </p>
			<p begin="00:02:48.433" end="00:02:51,466" style="1">but who also worked in the laboratory,</p>
			<p begin="00:02:51.466" end="00:02:55,466" style="1">as we all did in that time.</p>
			<p begin="00:02:55.466" end="00:02:58,732" style="1">Now, Henry Dawson was a Canadian,</p>
			<p begin="00:02:58.733" end="00:03:02,733" style="1">he was a British Canadian, very important.</p>
			<p begin="00:03:02.733" end="00:03:11,799" style="1">And he was absolutely convinced that anything done in England had to be right [laughter]. </p>
			<p begin="00:03:11.800" end="00:03:18,733" style="1">And I can assure you this, I am not trying be to play with this fact.</p>
			<p begin="00:03:18.733" end="00:03:21,499" style="1">He was intensely [emotional?] about it.</p>
			<p begin="00:03:21.500" end="00:03:24,800" style="1">Because he was so [emotional?] about it,</p>
			<p begin="00:03:24.800" end="00:03:29,800" style="1">he decided he would try to repeat the experiments, during the summer, </p>
			<p begin="00:03:29.800" end="00:03:33,800" style="1">that&apos;s the time when I participated in the project with him,</p>
			<p begin="00:03:33.800" end="00:03:38,933" style="1">and he actually duplicated Griffith&apos;s results.</p>
			<p begin="00:03:38.933" end="00:03:44,399" style="1">If I mention this it is to convey to you</p>
			<p begin="00:03:44.400" end="00:03:50,866" style="1">that in scientific life there are all sorts of human elements</p>
			<p begin="00:03:50.866" end="00:03:54,566" style="1">that are not sufficiently recognized.</p>
			<p begin="00:03:54.566" end="00:04:00,132" style="1">I think it probably confirmed in our laboratory if Henry Dawson</p>
			<p begin="00:04:00.133" end="00:04:05,399" style="1">had not been a British Canadian.  [Indistinct chatter]</p>
			<p begin="00:04:05.400" end="00:04:07,633" style="1">So he did repeat the experiment,</p>
			<p begin="00:04:07.633" end="00:04:12,899" style="1">and very soon he did what Griffith had not been able to do.</p>
			<p begin="00:04:12.900" end="00:04:20,200" style="1">He showed that the transformation of the pneumococcus types could occur not only in the mouse,</p>
			<p begin="00:04:20.200" end="00:04:25,866" style="1">through very messy, complicated experiments, but could be done in the test tube,</p>
			<p begin="00:04:25.866" end="00:04:29,666" style="1">and this was an achievement of phenomenal importance,</p>
			<p begin="00:04:29.666" end="00:04:37,399" style="1">because it meant that from then on it could be studied by all sorts of techniques.</p>
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