1. M7(R1) assessment and control of DNA reactive (mutagenic) impurities in pharmaceuticals to limit potential carcinogenic risk Publication: Silver Spring, MD : Center for Drug Evaluation and Research, March 2018 Subject(s): Carcinogenicity Tests -- standardsCarcinogensChemistry, PharmaceuticalDNA Damage -- geneticsDrug Contamination -- prevention & controlMutagenicity Tests -- standardsMutagensAcrylonitrile -- toxicityAniline Compounds -- toxicityBenzyl Compounds -- toxicityBis(Chloromethyl) Ether -- toxicityEthyl Chloride -- toxicityHydrazines -- toxicityHydrogen Peroxide -- toxicityMethyl Chloride -- toxicityNitrobenzenes -- toxicityNo-Observed-Adverse-Effect LevelQuality ControlToxicity Tests -- standardsHumansUnited StatesUnited States. Department of Health and Human Services.United States. Food and Drug Administration.
2. Letter from Paul Kotin to Mary Lasker Publication: Produced: 8 April 1966 Subject(s): CarcinogensFinancial Support Archival Collection: The Mary Lasker Papers (Profiles in Science)
3. Six suggested research activities to be initiated or expanded at the National Cancer Institute with additional funding Publication: Produced: 8 April 1966 Subject(s): CarcinogensCarcinogenicity TestsFinancial Support Archival Collection: The Mary Lasker Papers (Profiles in Science)
4. The Health Consequences of Smoking: Cancer: A Report of the Surgeon General Publication: United States. Office on Smoking and Health, 1982 Subject(s): Tobacco Use CessationTobacco Use DisorderTobacco Smoke PollutionCarcinogens Archival Collection: Reports of the Surgeon General (Profiles in Science)
5. The Health Consequences of Using Smokeless Tobacco Publication: United States Public Health Service, April 1986 Subject(s): NicotineTobaccoTobacco, SmokelessPrecancerous ConditionsNeoplasmsTobacco Use DisorderCarcinogensNicotine Archival Collection: Reports of the Surgeon General (Profiles in Science)
6. The Health Consequences of Involuntary Smoking: A Report of the Surgeon General Publication: United States. Office on Smoking and Health, 1986 Subject(s): Tobacco Smoke PollutionInhalation ExposureWorkplacePublic FacilitiesCarcinogens Archival Collection: Reports of the Surgeon General (Profiles in Science)
7. M7(R2) assessment and control of DNA reactive (mutagenic) impurities in pharmaceuticals to limit potential carcinogenic risk: guidance for industry Publication: Silver Spring, MD : Center for Drug Evaluation and Research, July 2023 Subject(s): CarcinogensDrug Contamination -- prevention & controlDrug DevelopmentDrug IndustryGovernment RegulationMutagenicity TestsMutagensUnited StatesUnited States. Food and Drug Administration
8. Letter from Sol Spiegelman to Van R. Potter Publication: Produced: 11 July 1945 Subject(s): EnzymesCarcinogensNeoplasms Archival Collection: The Sol Spiegelman Papers (Profiles in Science)
